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Global Rheumatoid Arthritis Drugs Market US$ 36.

3 billion by 2021

The global rheumatoid arthritis drugs market expected to reach US$ 36.3 billion by 2021, growing at CAGR 8.5% over
the forecast period 2017-2021, mainly due to number of promising RA therapies are in development and drug

Rheumatoid arthritis (RA) is a chronic autoimmune condition of the connective tissue in synovial joints characterized
by inflammation that can lead to impaired movement and disability. Small-molecule disease-modifying anti-
rheumatic drugs (DMARDs) include methotrexate (Trexall, Otrexup, Rasuvo), leflunomide (Arava),
hydroxychloroquine (Plaquenil) and sulfasalazine (Azulfidine). Biological drugs such as inhibitors of tumor necrosis
factor (TNF) blocks the activity of key inflammatory mediators that give rise to the main characteristics of RA. These
include infliximab (Remicade), adalimumab (Humira), etanercept (Enbrel), golimumab (Simponi) and certolizumab
pegol (Cimzia). Several other biological response modifiers such as checkpoint inhibitor, cytotoxic T lymphocyte-
associated protein 4 (CTLA4) inhibits the production of inflammatory cytokines such as TNF, interferon- and
interleukin-2 (IL-2). These include abatacept (Orencia), Rituximab (MabThera), and Tocilizumab
(Actemra/RoActemra). Janus Kinase (JAK) inhibitors such as Tofacitinib (Xeljanz), Filgotinib and baricitinib are
recently approved by the US FDA, while a number of promising RA therapies are in development. The RA therapies
by category in clinical pipeline (phase II and III) include JAK inhibitors (ABT-494, Baricitinib, Filgotinib), IL-6 inhibitors
or IL-6R antagonists (ALX 0061, Clazakizumab, Sarilumab, Sirukumab), and Others (Denosumab, Mavrilimumab).

Browse Rheumatoid Arthritis Drugs Market by Drug Class - Disease-Modifying Anti-Rheumatic Drugs (DMARDs),
Tumor Necrosis Factor (TNF) Inhibitors, Janus Kinase (JAK) Inhibitors, Other Biologics and Forecast 2017-2021. The
global rheumatoid arthritis drugs market research report provides market size (Revenue USD Million 2014 to 2021),
market share analysis, growth trends and forecast (CAGR%, 2017 to 2021). The global rheumatoid arthritis drugs
market research report is further segmented by geography into North America (U.S., Canada), Latin America (Brazil,
Mexico, Rest of LA), Europe (U.K., Germany, France, Italy, Spain, Rest of EU), Asia Pacific (Japan, China, India, Rest of
APAC), and Rest of the World. In addition, the global rheumatoid arthritis drugs market report provides the detailed
market landscape (market drivers, restraints, opportunities), market attractiveness analysis, and market profitability
analysis by key products and regions or countries. The report also tracks the major competitors operating in the
global market by company overview, financial snapshot, major products, technologies, services offered and recent
developments. Major players operating in the global rheumatoid arthritis drugs market and profiled in this report
include AbbVie, Ablynx, Alder Biopharmaceuticals, Amgen, Bristol-Myers Squibb, Centocor, Daiichi Sankyo, Eli Lilly,
Galapagos NV, Genentech (Roche), Gilead, GlaxoSmithKline, Incyte Corp., Janssen Biotech, Johnson & Johnson,
MedImmune, Merck & Co., Pfizer, Regeneron, Sanofi, and UCB.

1. Drug Class
1.1. Disease-Modifying Anti-Rheumatic Drugs (DMARDs)
1.2. Tumor Necrosis Factor (TNF) Inhibitors
1.3. Janus Kinase (JAK) Inhibitors
1.4. Other Biologics

2. Geography
2.1. North America (U.S., Canada)
2.2. Latin America (Brazil, Mexico, Rest of LA)
2.3. Europe (U.K., Germany, France, Italy, Spain, Rest of EU)
2.4. Asia Pacific (Japan, China, India, Rest of APAC)
2.5. Rest of the World

3. Company Profiles
3.1. AbbVie
3.2. Ablynx
3.3. Alder Biopharmaceuticals
3.4. Amgen
3.5. Bristol-Myers Squibb
3.6. Centocor
3.7. Daiichi Sankyo
3.8. Eli Lilly
3.9. Galapagos NV
3.10. Genentech (Roche)
3.11. Gilead
3.12. GlaxoSmithKline
3.13. Incyte Corp.
3.14. Janssen Biotech
3.15. Johnson & Johnson
3.16. MedImmune
3.17. Merck & Co.
3.18. Pfizer
3.19. Regeneron
3.20. Sanofi
3.21. UCB

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