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Irritable
Bowel
Syndrome
- Overview
- Details of an independent study
carried out by University College
London to establish if 8 leading
probiotics are effective as they claim
1
+ Irritable Bowel Syndrome 2
2
+ IBS Sufferers 3
IBS is multi-faceted -
predominately only single
symptom products available
4
+ Probiotic consumers 5
Prevention Treatment
Those with no Those with
functional GI chronic,
disorder or debilitating
diagnosed disorders
health such as IBS
condition
View
Want to offset probiotics as Looking for a
Often
negative side a form of safe and
dissatisfied
effects relating daily effective way
with
to poor diet insurance to relieve
conventional
and lifestyle against ill symptoms
treatments
health long-term
5
+ Probiotic efficacy 6
Many claim to
Most
work" or
manufacturers
survive", but
have avoided
they all use
comparisons
different strains,
with realistic
tests and
tests
conditions
6
+ So do they work? 7
7
+ So do they work? 8
Scientists at
Do they contain University College
the claimed Do they possess London (UCL)
number of viable the robustness independently
organisms to transit through conducted compared
stated on the to the gut? leading probiotic
label? brands to find out the
truth
8
UCL SCHOOL OF PHARMACY
1.Actimel 5. Probio7
2.Align 6. Yakult
3.Symprove 7. VSL#3
4.Biobalance 8. Bio-kult
10
To subject the products to three
challenge tests to assess if the bacteria:
ARRIVED
In a live state
SURVIVED
Stomach acid transit
THRIVED
In the target area of the gut
11
1. Enumeration Test
Were the claimed number
of bacteria recoverable?
2. Tolerance Test
Do the bacteria survive
exposure to gastric Juices?
12
Did the bacteria arrive?
13
Only dairy-based (Actimel, Yakult) or water-
based (Symprove) probiotics delivered
100% or more than the claimed content
Arrived
Delivers at least 75%
of the amount claimed
for the product
Symprove
Yakult
Actimel
14
Did the bacteria survive?
15
Only two products survived stomach transit
time (120 minutes), with one of these
continuing to decline
Survived
After exposure, are the
surviving bacteria still
concentrated enough?
Symprove VSL#3
Did the bacteria thrive?
17
Only three products showed signs of
strong growth within 10 hours. Others
showed very slow, or even no growth
Thrived
Colony starts growing
strongly within 10
hours to hit the target
areas in the gut
VSL3
Actimel
Symprove
18
Summary
To be successful
probiotic product needs
to beat all three
challenge tests
Safely arrive,
survive stomach
acids, and thrive in
the target area of the
gut
19
Overall results
20
The big probiotic scam
21
Is your probiotic dead or alive?
22