INTEGRATIVE ONCOTHERAPY - LESSONS FROM OUR RESEARCH Sanjana.G’, Samuel Justin Raj.C’, Merish.S*, Thomas.M.Walter* * Thitd Year BSMS,Government Siddha Medical College,Palayamkottai ? Consultant,Walters'Siddha Research Centre, Tirunelveli www siddhawalter org, “Asst Prof, Department of Pharmacology, Government Siddha Medical College,Palayamkottai Lela leH + Cancer still remains as the number one dreaded disease of the World. + In the current scenario, the treatment modalities include prolonged hospitalization, treatment adherence and drastic side effects. + Integrated Medicine would be having immense positive effect over the existing + Our innovation - a Poly herbal formulation to alleviate undesired effects of Radiation and Chemo therapy. + Our study drug was given together along with the conventional chemotherapy and radiation. + The positive synergetic effects of the combined integrative medicine were noted. Ste tA + In vitro cel line studies were done using A549 carcinoma cells. + The cancer cell viability activity of the test drug was studied and evaluated by direct observation of cells by Inverted phase contrast microscope and followed by MTT assay. rei) Oso ole dustpd 2) Agape hcen€) Ca Shrkoge a (onsans bein fy Sovened nasa cometon (SEIS Wet + The study results revealed that the trail drug exhibits 62.59% of Viability even at the minimum concentration of 6.25 g/ml. + Besides anticancer property, the trial drug also exhibited lessening of the side effects involved in chemotherapy and radiation therapy. + The observed alleviations of side effects include nausea, vomiting, less pigmentation and lesser loss of hair Ses + This preliminary trial from our Walters’ Siddha Research Centre (WWSRC) clearly indicates the positive effect of Siddha formulations when combined with mainstream radiation and chemotherapy. + The trial drug itself exhibited anticancer property although its used or treating diseases other than cancer as per Siddha literatures which can be viewed as an accidental finding + This is only a preliminary tal with available infrastructure. Much more studies and mult- centric clinical trials are needed to explore the synergetic effect of integrative medicine in treating cancers. WSRC_ | CIMR,MANIPAL UNIVERSITY-2017