Beruflich Dokumente
Kultur Dokumente
No - 40 |
BIOLOGY
INVESTIGATORY
PROJECT
ON RECENT DISEASES - EBOLA
Ebola Proteins
Initial symptoms are nonspecific - may
include fever, chills, myalgias, and
Symptoms of Ebola
malaise.
Other symptoms:
Epidemiology
Ebola Subtypes
Transmission Of Ebola
Symptoms Of Ebola
Diagnosis Of Ebola
Treatment Of Ebola
TRANSMISSION OF
EBOLA
Ebola Subtypes
Ebola-Zaire
Ebola-Zaire
(ZEBOV) (ZEBOV)
Ebola- Ebola-Sudan
Sudan (SEBOV)
Ebola Ivory-
(SEBOV)
Coast (ICEBOV)
Ebola Ebola-Reston
Ivory-Coast (REBOV)
(ICEBOV)
Ebola-Reston
(REBOV)
MOLECULAR STRUCTURE
Characterization of the
virus
Order: Mononegavirales
Family: Filoviridae
Genus: Ebolavirus
Species: Ebola-Zaire, Ebola-Sudan,
Ebola-Cote d-Ivoire, Ebola-Reston
Morphology under
electron microscope
filamentous, enveloped RNA virus
approx. 19 kb in length (1 kb =
1000 RNA
bases/nucleotides) or 60-80 nm in
diameter
single-stranded, linear, non-
segmented
negative-sense RNA (encoded in a
3 to 5 direction)
appears to have spikes due to
glycoprotein on outside membrane
Structure of Ebola
genome and proteins
Transcribed into 8 sub-genomic
mRNA proteins: 7 structural and 1
nonstructural
7 structural proteins:
nucleoprotein (NP)
glycoprotein (GP)