188 views

Uploaded by Chandraprakash Shah

BSc V-VI Syllabus 2017-18 by Christ College - Rajkot

- Physics I 2011-12
- UT Dallas Syllabus for math3312.501.11s taught by Mieczyslaw Dabkowski (mkd034000)
- 1802.00227 - Is Quantum Mechanics Creationism, And Not Science
- Wave Funtion and Born Interpretataion of Wave Function Plus Schrodinger Wave Equation
- Kinematics and Dynamics of Lower body of Autonomous Humanoid Biped Robot.docx
- Calc_Var.pdf
- UT Dallas Syllabus for phys6400.001.09f taught by Joseph Izen (joe)
- M.Sc. Mathematics syllabus 2017-19.pdf
- 033 - Pr 20 - Quartic Lagrangian
- Seminar Paper
- Chapter 3
- lec10
- Resumen del capítulo 1 de Mecánica Clásica de Landau y Lifshitz
- 3C25 Solid State Physics old notes 4 of 11 (UCL)
- Constrained Multibody Dynamics With Python
- Lesson Plan in Mathematics Lurica
- Time Crystals From Minimum Time Uncertainty
- 274802854-Engineering-Chemistry.pdf
- Explanation of Abstract Algebra for Non Mathematicians
- Physics II SP

You are on page 1of 53

r-;::Re-accredited by;::;l

L!c_J

CHRIST COLLEGE, RAJKOT

(Affiliated to Saurashtra University, Rajkot)

Bachelor of Science (Semester - V & VI)

BSc Syllabus 2017-18 Semester V & VI

CONTENTS

1. Physics 01

2. Mathematics 08

3. Chemistry 15

4. Biotechnology 30

5. Microbiology 39

BSc Syllabus 2017-18 Semester V&VI Physics

PHYSICS

SEMESTER-V

Mathematical Physics

(i) Fourier Series

Definition and derivation of the co-efficients of Fourier Series[7.1], Cosine & Sine Series[7.1], Solved

problems on Fourier Series, Applications of Fourier analysis(square wave & full wave rectifier)[7.9],

Problems.

Basic reference book : Mathematical Physics by Rajput, (Pragati Prakashan), Meerut, India.

Classical Mechanics

(i) Lagrangian Formulation

Constraints[8.1], Generalised coordinates[8.2], DAlemberts principle[8.3], Lagrange equations[8.4],

A general expression for kinetic energy[8.5], Symmetries and laws of conservation[8.6], Cyclic or

ignorable coordinates[8.7], Velocity-dependent potential of electromagnetic field[8.8], Rayleighs

dissipation function[8.9], Problems.

(ii) Variational Principle: Lagranges and Hamiltons Equations

Configuration space[11.1], Hamiltons principle[11.4], Equivalence of Lagranges and Newtons

equations[11.5], Advantages of the Lagrangian formulation-electro-mechanical analogies[11.6],

Lagranges undetermined multipliers[11.7], Applications of the Lagrangian method of undetermined

multiplies[11.9], Hamiltons equations of motion[11.10], Some applications of the Hamiltonian

formulation[11.11], Phase space[11.12], Problems.

Basic reference book for (i) & (ii) : Introduction to Classical Mechanics by Takwale and Puranik. (Tata McGraw

Hill Pub Comp. Delhi).

Quantum Mechanics

(i) The Schrodinger equation and Stationary States

Schrodinger equation: A Free Particle in One Dimension[2.1], generalization to Three Dimensions[2.2],

The Operator Correspondence and the Schrodinger equation for a Particle subject to forces[2.3], Physical

interpretation on , Normalization and Probability interpretation[2.4], Non-Normalizable Wave

Functions and Box Normalization[2.5], Conservation of Probability[2.6], Expectation Values,

Ehrenfests Theorem[2.7], Admissibility Conditions on the wave function[2.8], Stationary states: The

Time-Independent Schrodinger equation[2.9], A particle in a Square Well potential, Bound states in a

Square Well(E<0)[2.11]; (a) Admissible solutions of Wave equation (b) The Energy Eigenvalues-

Discrete Spectrum (c) The Energy Eigen functions:Parity (d) Penetration into Classically Forbidden

Regions, The Square Well:Non-localized States (E>0)[2.12].

(ii) General Formalism of Wave Mechanics

Schrodinger Equation and the Probability Interpretation for an N-Particle System[3.1], The Fundamental

Postulates of Wave Mechanics: (a) Representation of States (b) Representation of Dynamical

Variables[3.2], The Adjoint of an Operator, and Self-Adjointness[3.3], The Eigen value Problem;

Degeneracy[3.4], Eigen values and Eigen functions of Self-Adjoint Operators[3.5], The Dirac-Delta

function[3.6].

Basic Reference Book for (i) & (ii) :Text Book of Quantum Mechanics by Mathews and Venkateshan, (Tata

McGraw Hill Pub. Comp.)

Reference Books:

1. Mathematical Physics - P.K.Chattopadhyay

2. Mathematical methods in Physical Science - M.L.Bose, John Willy & Sons

3. Classical Mechanics - Gupta, Kumar and Sharma. Pragati Prakashan, Meerut, India

4. Classical Mechanics - Goldstein

5. Quantum Mechanics - Ghatak and Loknathan, Macmillan India Ltd., Delhi

6. Quantum Mechanics - Ajoy Ghatak

7. Elements of Quantum Mechanics - Kamal Singh and S.P.Singh, S.Chand Co.

BSc Syllabus 2017-18 Semester V&VI Physics

Electricity and Magnetism

(i) Electrostatics :

Electric flux and Gauss law (differential form) [2.2.1], Divergence of E [2.2.2], Curl of E [2.2.4],

Introduction to Potential [2.3.1], Poissons and Laplaces equation [2.3.3], the work done on a moving

charge [2.4.1]

(ii) Magnetostatics

Electric Current and current density [5.1.3], Magnetic field of steady current [5.2.1], Divergence of B

[5.3.2], Curl of B [5.3.3], Amperes law [5.3.4], Comparison of Magnetostatics and Electrostatics

[5.3.5], Vector potential [5.4.4]

(iii) Electrodynamics

Faradays law [7.2.1], Maxwells equations [7.3.1], Scalar and vector potentials of electrodynamics fields

[7.4.1], Poynting theorem[7.5.2]

Basic reference book for (i), (ii) and (iii) : Introduction to Electrodynamics by D.J.Griffiths [Prentice Hall of India

Pvt. Ltd, Delhi]

(iv) Motion of Charged Particles

Charged particle in a uniform magnetic field B [8.1], Force on a current in Magnetic field [8.4], Charged

particle in Electric and magnetic fields [8.8]

Basic reference book for (iv) : Electricity and Magnetism by A.S.Mahajan and A.A.Rangwala, [Tata McGraw

Hill]

(v) Power Systems

Generation of Electrical energy[1.2], Sources of Energy[1.3], Fuels[1.8 to 1.10], Power stations[2.1],

Thermal Power station[2.2, 2.3], Hydro power station[2.7, 2.8, 2.10], Diesel power station[2.11],

Nuclear Power station[2.13], Gas power plant [2.13]

Basic reference book for (v) : Principles of Power Systems by V.K.Mehta and Rohit Mehta, (S.Chand &

Company Ltd.)

Reference Books :

1 Electricity and Magnetism - Mahajan and Rangwala

2 Classical Electrodynamics J.D.Jackson

3 Electricity and Magnetism R. Murugeshan

4 Electromagnetics B.B.Laud

5 Electricity and Magnetism K.K.Tiwari

6 Electricity and Magnetism Berkeley Physics Course, Vol. II

Solid State Electronics

(i) Multi-stage Transistor Amplifiers

Multistage Transistor Amplifier[14.1], RC coupled Transistor Amplifier[14.3], Transformer coupled

Amplifier[14.4], Direct coupled Amplifier[14.5], Comparison of Different types of coupling[14.6].

(ii) Transistor Audio Power Amplifiers

Transistor Audio Power Amplifier[15.1], Difference between Voltage and Power amplifier[15.2],

Performance Quantities of power amplifier[15.3], Classification of Power amplifier[15.4], Expression

for Collector Efficiency[15.5], Efficiency of Class A Amplifier[15.6], Maximum Efficiency of

Transformer Coupled Class A Power amplifier[15.7], thermal Runaway[15.9], Heat sinks[15.10],

Mathematical Analysis[15.11], Push pull Amplifier[15.15], Complementary Symmetry

Amplifier[15.16].

(iii) Regulated D.C. Power Supply

Ordinary D.C. power supply[20.1], Important terms[20.2], Regulated Power supply[20.3], Types of

voltage regulators[20.4], Transistor series voltage regulator[20.6], Series feedback voltage

regulator[20.7], Short-circuit protection[20.8], Transistor shunt voltage Regulator[20.9]

Basic Reference book for (i), (ii) & (iii):Principles of Electronics by V.K.Mehta & Rohit Mehta. (S.Chand

& Company Ltd.)

(iv) Electronic Instruments

Laboratory Instrument: Analog and Digital Instruments[37.2], Functions of Instruments[37.3],

Electronic versus Electrical Instruments[37.4], Essentials of an Electronic Instrument[37.5], Digital

voltmeter[37.24], Cathode Ray Oscilloscope[37.25-26], Frequency Determination[37.36], Application

of CRO[37.37].

BSc Syllabus 2017-18 Semester V&VI Physics

Basic Reference book for (iv) : Basic Electronics by B.L.Theraja (S.Chand & Company Ltd.)

Reference Books

1. Electronic Devices & Circuits by Allen Mottershad, Prentice-Hall of India Pvt. Ltd. Delhi

2. Electronic Devices & Circuits Theory by Boylestead & Nashelsky

3. Handbook of Electronics by Kumar & Gupta, Pragati Prakashan, Meerut, India

4. Principal of Electronics by Malvino, McGraw Hill International Editions

Optics

(i) Interferometer :

Michelsons interferometer [15.7.1 15.7.7], Applications of Michelson interferometer [15.8.1 15.8.4],

Multiple beam interference [15.11.1 15.11.4], Fabry Perot Interferometer and Etalon [15.12.1

15.12.3], Lummer Gehreke Plate [15.13].

(ii) Polarization :

Polarization by Double refraction[20.5.5], Nicol Prism[20.6.1], Anisotropic Crystals[20.7], Calcite

Crystal[20.8.1 -20.8.3], Huygens explanation of Double Refraction[20.9.1 20.9.2], Phase Difference

between e-ray and o-ray[20.13], Superposition of waves linearly polarized at right angles[20.14], Types

of polarized light[20.15], Retarders or wave plates[20.17.1 20.17.2], Analysis of polarized light[20.20],

Babinet compensator(only construction)[20.21], Artificial double refraction[20.29.1 20.29.4],

LCDs[20.30].

Basic reference book for (i) and (ii) : A textbook of Optics by N.Subrahmanyam, Brij Lal &

M.N.Avadhanulu (S.Chand & Company Ltd.)

(iii) Electron Microscopy

Principles and Applications of SEM, TEM and AFM (from reference book).

Reference Books:

1 Principles of Optics Mathur & Pandya

2 Interferometry Tolanski

3 Fundamentals of Optics D.R.Khanna & H.R.Gulati

4 A Textbook of light D.N.Vasudeva

5 Fundamentals of Optics Jenkins & White

6 Optical Electronics A.K.Ghatak & K. Thyagarajan

7 Modern Physical Techniques in Material Technology Mulvey & Webster

Spectroscopy

(i) Atomic Spectroscopy

The spinning electron [3.1], Space quantization[3.2], Quantum numbers and their physical

interpretations[3.3], Zeeman effect and experimental study of Zeeman effect[9.1 and the introduction

before it], Classical interpretation of Normal Zeeman effect[9.2], Vector atom model and Normal

Zeeman effect[9.3], Vector atom model and Anomalous Zeeman effect[9.4 note: *in the equations may

be overlooked for convenience], Paschen-Back effect[9.5], Stark effect[9.11].

Basic Reference Book for (i): Elements of Spectroscopy by Gupta, Kumar, Sharma (Pragati Prakashan)

(ii) Molecular Spectroscopy

Introduction [Pg 764 to second paragraph of page 765], Theory of pure rotational Spectra [769 to second

para of 770], Theory of rotational vibrational Spectra[771 to second para of 772], Theory of electronic

band Spectra[773 to second para 774].

Basic Reference Book for (ii) : Atomic Physics by J.B.Rajam. (S.Chand & Company Ltd.)

(iii) Raman Spectra

Raman effect and its Salient features[4.0], Observation of Raman Spectra[4.1], Classical theory of

Raman effect[4.2], Quantum theory of Raman effect[4.3], Applications and its Importance.

Basic Reference Book for (iii): Elements of Spectroscopy: Gupta, Kumar & Sharma, (Pragati Prakashan)

Reference Books:

1. Atomic Physics - J.B.Rajam. (S.Chand & Company Ltd.)

2. Optics and Spectroscopy - R.Murugeshan & Kiruthiga Sivaprashatha. (S.Chand & Company Ltd.)

3. Optical Electronics - A.K.Ghatak and K. Thyagarajan. Cambridge Uni. Press.

BSc Syllabus 2017-18 Semester V&VI Physics

SEMESTER-VI

Nuclear Physics

(i) Accelerators (Construction and working of these)

Synchrocyclotron, Proton Synchrotron [11.7], Alternating gradient accelerator[11.9], Betatron.

Basic Reference Book for (i) : Nuclear Physics by D.C.Tayal, (Himalaya Publishing House)

(ii) Detector of Nuclear radiations

Interaction between Energetic Particle and matter [29.2], Ionization Chamber[29.3], Solid state

Detector[29.6], GM Counter[29.6], Scintillation Counters[29.12].

(iii) Nuclear Reaction

Rutherford experiment[34.1], Q-value of Nuclear reaction[34.3], Nuclear reaction[34.4], Energy balance

in Nuclear reaction[34.5], Threshold energy of Endoergic reaction[35.1], Nuclear Transmutation[34.7].

(iv) Nuclear Fission and Fusion

Nuclear fission[35.2], Energy released in fission[35.3], Bohr & Wheelers theory of fission, Chain

reaction[35.4], Atom bomb[35.5], Nuclear Reactors[35.6], Nuclear fusion[35.7], Source of stellar

energy[35.8], Thermonuclear reactions[35.9], Pressurized Water Reactor[36.1], Boiling Water

Reactor[36.2], Fast Breeder Reactor[36.3], Fusion Reactor[36.5], Plasma Confinement[36.6].

(v) Elementary Particles

Introduction [38.1], Particles & Antiparticles[38.2], Antimatter[38.3], The fundamental

Interactions[38.4], Elementary particle Quantum numbers[38.5], Conservation laws and

symmetry[38.6], Quark model[38.7].

Basic Reference Book for (ii), (iii), (iv) & (v):Modern Physics by R.Murugeshan & Kiruthinga Sivaprasatha,

(S.Chand & Company Ltd.)

Space Physics

(i) The Universe (description only)

Stars: Brightness, Colour, Temperature, Spectra, Size, HR diagram, Birth of stars, Red giant stars, White

dwarfs, Neutron stars, Black holes, Supernova, Types of Galaxies, Our Galaxy and External Galaxies.

(ii) Concepts and foundations of Remote Sensing

Energy restores and Radiation principles, Energy interactions in the atmosphere, energy interactions with

earth surface features, Data acquisition and interpretations, Reference data, The Global Positioning System, An

idea of remote sensing systems, Practical applications of remote sensing, Land and Geographic information

system(in brief).

Basic Reference Book: Remote Sensing and Image Interpretation by Lillesand and Kiefer, John Wiley & Sons,

4th Edi.

Reference books:

1. Nuclear Physics by D.C.Tayal

2. Nuclear Physics by Roy and Nigam

3. Nuclear Physics by Irving Kaplan

4. Nuclear Physics by S.N.Ghoshal, S.Chand & Co.

5. Atomic Physics by J.B.Rajam, S.Chand & Co.

6. Solar System by N.C.Rana

7. Structure of the Universe by Narlikar

8. Source Book on Space Science by Glasston.

PAPER P-602 (STATISTICAL MECHANICS, SOLID STATE PHYSICS & PLASMA PHYSICS)

Statistical Mechanics

(i) Classical Distribution Law

Phase Space(till the derivation of d>=h3)[1.1], Volume in Phase Space[1.2], Micro States and Macro

States(number of microstates accessible to a macroscopic system onwards not included)[2.1], Stirlings

approximation[2.2], Thermodynamic Probability[2.3], Division of Phase Space into Cells[2.6], Classical

Maxwell Boltzmann Distribution law[2.7].

BSc Syllabus 2017-18 Semester V&VI Physics

Derivation of the distribution law of Bose-Einstein Statistics[6.2], Derivation of the distribution law of

Fermi Dirac Statistics[6.3], Comparison of the Maxwell-Boltzmann, Bose-Einstein and Fermi-Dirac

Statistics[6.6], Blackbody radiation and the Plancks radiation law[6.10], Specific heat of Solids[7.2],

Dulong and Petit law[7.2.1], Einsteins theory of Specific heat of Solids[7.2.2], Debyes theory of

Specific heat of Solids[7.2.3], Free electron model and Electronic emission[9.3].

Basic Reference Book for (i) & (ii) : Elementary Statistical Mechanics by Gupta and Kumar, (Pragati Prakashan)

Solid State Physics

(i) X-Ray Diffraction

Determination of Crystal Structure[2.1], Laue Method[2.4], Rotating Crystal Method[2.5], Powder

Method[2.6].

(ii) Superconductivity

Experimental Aspects[16.1], Influence of external agents on Superconductivity[16.2], Meissner

effect[16.3], Critical field of Small Specimens[16.6], Thermodynamic of Superconducting

transition[16.7], Alloys & Compounds[16.10], Londons theory[16.14], Josephson effects[16.17], BCS

theory[16.18.1 to 4], Applications of Superconductivity(in brief from reference book).

(iii) Photoconductivity and Luminiscence

History[17.1], Photoconducting materials[17.2], Electronic transitions in Photo conductors[17.3], Photo

sensitivity[17.6], Trapping and its effects[17.11], Luminiscence effect[17.12], Models of Luminiscence

in Sulphide Phosphors[17.13], Electro luminescence[17.17].

Basic Reference Book for (i), (ii) & (iii) : Fundamentals of Solid state Physics by Saxena, Gupta and Saxena,

(Pragati Prakashan)

(iv) Liquid Crystals

Liquid Crystals[43.1], Thermotropic Liquid Crystals[43.2], Lyotropic Liquid Crystals[43.3],

Applications [43.4]

Basic Reference Book for (iv) : Modern Physics by R.Murugeshan and Kiruthiga Sivaprasath (S.Chand &

Company Ltd.)

Plasma Physics

Introduction[19.1], Interaction of Particles[19.2], Concept of Collisions[19.3], Excitation of Atoms and

Molecules[19.7], Dissociation of Molecules[19.7.1], Ionization of Atoms and Molecules[19.7.2],

Recombination[19.7.3] and Photo Ionization[19.7.4], Excitation and Ionization by stages[19.7.5], Production of

Plasma[19.11], Plasma Oscillations[19.13], Properties of Plasma[19.14], Plasma Radiation, Applications of

Plasma(from reference book).

Basic Reference book: Fundamental of Solid State Physics by Saxena, Gupta, Saxena, (Pragati Prakashan)

Reference books:

1. Statistical Mechanics by Mayor and Mayor

2. Statistical Mechanics by Agrawal and Eisner

3. Introduction to Solid State Physics by Charles Kittle (7th edition), John Wiley & Sons

4. Solid State Physics by A.J.Dekker, Macmillan India Ltd.

5. Introduction to Solid by L.V.Azaroff, Tata McGraw Hill Pub.

6. Solid State Physics by Puri and Babbar, S.Chand Comp. Ltd.

7. Introduction to Plasma Physics by Chen

8. Superconductivity & Superconducting Materials by Narlikar and Ekbote.

(i) Solid State Switching Circuits

Switch[21.1], Mechanical switch[21.3], Electronic switches[21.5], Advantages of electronic

switches[21.6], Switching transistors[21.8], Switching action of Transistor[21.9], Multivibrators[21.10],

Types of Multivibrators[21.11], Transistor Astable Multivibrators[21.12], Transistor Monostable

Multivibrators[21.13], Transistor Bistable Multivibrators[21.14], Differentiating circuit[21.15],

Integrating circuit[21.16], Clipping circuits[21.18], Application of Clippers[21.19], Clamping

circuits[21.20], Basic idea of a clamper[21.21].

Basic Reference book for (i):Principles of Electronics by V.K.Mehta & Rohit Mehta, (S.Chand &Company

Ltd.)

(ii) Thyristor and their applications

BSc Syllabus 2017-18 Semester V&VI Physics

Two transistor analogy of SCR[4.8], Comparison between Thyristor and Transistor[4.10], Methods of

triggering a thyristor[4.11], DIAC[4.14], TRIAC[4.15], Rectifier circuits using SCR[4.17<1,2 and 3>],

Solid State Switching Circuits using Thyristor[4.18,<1,2,3and 4>], Choppers(in brief)[5.2].

(iii) Thyristor Control Circuit

Temperature Control[7.2], Illumination Control using DIAC & TRIAC[7.3.2], Light active Turn off

Circuit using DIAC, TRIAC & LDR[7.5], Off at Dark Circuit[7.6], Automatic Street Light Circuit Using

LDR & SCR[7.7], Emergency light[7.8], Automatic Water Level Indicator[7.9], Automatic Battery

Charger[7.10], Light Operated alarm[7.11], Burglar Alarm[7.12], Battery Operated Inverter[7.15].

Basic Reference Book for (ii) & (iii) : Industrial Electronics and Control by S.K.Bhattacharya & S.Chatterjee.

(Tata McGraw Hill Pub).

(iv) Integrated Circuits

Integrated Circuits[31.2], Advantages & Drawbacks of ICs[31.3 & 4], Scale of Integration[31.5],

Classification of ICs by Structure[31.6], Comparison between different ICs[31.7], Classification of ICs

by Function[31.8], Linear Integrated Circuits[31.9], Digital Integrated Circuits[31.10], Monolithic ICs

are Made[31.12], Fabrication of IC Components[31.14 & 15], Popular Applications of ICs[31.16], OP-

AMP[31.18], OP-AMP Symbol[31.19], Ideal Operational Amplifier[31.20], OP-AMP

Applications[31.24], Linear Amplifier[31.25], Adder[31.27], Subtractor[31.28], Integrator[31.29],

Differentiator[31.30], Comparator[31.31].

(v) Transducer

Transducer[36.1], Classification of Transducers[36.2 & 3], Resistive Position Transducer[36.4],

Resistive Pressure Transducer[36.5], Inductive Pressure Transducer[36.6], Capacitive Pressure

Transducer[36.7], Self-generating Inductive Transducers[36.8], Linear Variable Differential

Transformer(LVDT)[36.9], Piezoelectric Transducer[36.10], Strain Gauge[36.11], Temperature

Transducer[36.12], Resistance temperature detectors[36.13], Thermistor[36.14], Thermocouples[36.15],

Photoelectric Transducer[36.17], Various Types of Microphones[36.18].

Basic Reference Book for (iv) & (v): Basic Electronics by B.L.Theraja, (S.Chand & Company Ltd.)

(vi) Digital Logic Modules

Combinational and Sequential logic circuits. Multiplexer and Demultiplexer, Memory element, RS flip-

flop, Clocked RS flip-flop, D flip-flop, JK flip-flop, Clocked and 555 Timers (in brief)

Basic Reference Book : Digital Electronics by Malvino, McGraw Hill International Edition.

Reference Books:

1. Electronic Devices & Circuits by Allen Mottershad, Prentice-Hall of India Pvt. Ltd., Delhi

2. Electronic Devices & Circuits Theory by Boylestead & Nashelsky

3. Handbook of Electronics by Kumar & Gupta, Pragati Prakashan, Meerut, India

4. Principal of Electronics by Malvino, McGraw Hill International Editions

5. Modern Digital Electronics by R.P.Jain

6. A Text book of Digital Electronics by R.S.Sedha, S.Chand

7. Principles of Control Systems by Eugene Xavier and Joseph Cyril Babu, S.Chand

Semester V

LIST OF EXPERIMENTS

1. Determine the g using Katers Pendulum

2. Study of Damped Simple Harmonic Motion

3. Study of Fabry-Perot Etalon

4. Study of Lloyds Mirror

5. Study of Double Refraction in Calcite Prism

6. Study of Babinet Compensator

7. Study of Absorption spectra of Iodine

8. Comparison of Capacities by Mixture Method

9. Determine the constant of Ballistic Galvanometer

10. Determine the Self Induction of coils using Owens Bridge

11. Determine the Mutual Induction of coils using Ballistic Galvanometer

12. Study of Transformers coils using Bridge rectifier

13. Determine e/m using Magnetron/Helical Method

14. Study of h-Parameter of CE-Transistor using PCB

BSc Syllabus 2017-18 Semester V&VI Physics

16. Study of Complementary-Symmetry Power Amplifier

17. Study of Series Voltage Regulator using Transistor

18. Electronic voltmeter using FET

19. Study of Hartley/RC phase shift Oscillator using Transistors

20. Study of Hysterisis loop of Ferromagnetic Material

21. Study of Hall Effect

22. Measurement of frequency and phase using CRO

A minimum of 75% experiments shall be done by each student.

Semester VI

LIST OF EXPERIMENTS

1. Study of Resonance Pendulum

2. Determine the Youngs Modulus by Koeing Method

3. Determine the Elastic constants using Flat Spiral Spring

4. Study of Platinum Resistance Thermometer

5. Study of Searles Goniometer

6. Study of Edser-Butler Plate

7. Resolving power of Diffraction Grating

8. Study of the Output Wave form Clipping and Clamping circuit

9. Study of Astable Multivibrator

10. Study of Plancks constant using Photocell

11. Photo Conductivity of Selenium cell

12. Characteristics of SCR using PCB

13. Study of UJT as Relaxation Oscillator

14. Study of RS, D & JK Flip-flop

15. Study of OP-AMP using IC 741.(inverter, noninverter, adder and subtractor)

16. Study of IC 555 Timer circuit using PCB

17. Study of Multiplexer(4-1 line) and Demultiplexer(1-4 line) using IC 74153 and 74155 respectively

18. Study of Encoder & Decoder Circuit

19. Study of 4-bit Ripple Counter

20. Study of Modulation and Demodulation using IC 723

21. Study of Temperature ON-OFF Controller with Thermistor

22. Study of Linear Variable Differential Transformer(LVDT) Trainer

23. Study of Lamp Dimmer Circuit using DIAC and TRIAC

A minimum of 75% experiments shall be done by each student.

Basic Reference:

1. Practical Physics by C.L.Arora ( S.Chand)

2. Advanced Practical Physics by Chauhan & Singh. (Pragati Prakashan)

3. B.Saraf et al-Physics through experiments Vol.I & II

4. Electronic Laboratory Primer by Poorna Chandra & Sasikala, (S.Chand)

5. Practical Physics by Chattopadhyay, Rakshit & Saha.

Useful CD Rom for e-learning:

1. Hyper Physics 4. Virtual Physics Junior (Original PC CD

2. Encyclopedia of Science (D.K. Rom)

Multimedia) 5. Encyclopedia Britannica-2008

3. Physics Encyclopedia

Useful Website for e-learning:

1. www.wikipedia encyclopedia 5. www.howstuffworks.com

2. www.physic.about.com 6. www.colorado.edu/physics/2000

3. www.physic.org 7. www.idrs.org.physic.com

4. www.physicsclassroom.com 8. www.physlink.com

BSc Syllabus 2017-18 Semester V&VI Mathematics

Mathematics

SEMESTER V

Mathematical Analysis - 1

UNIT 1:

25 marks

[a] Riemann Integral:

Partitions and Riemann sums, Upper and lower R-integrals, R-integrability, The integral as

limit, Some classes of integrable Functions, Properties of integrable function.

[b] Continuity, Derivability of the integral functions, Fundamental theorem of integral calculus,

Mean theorem of Integral calculus.

[c] Metric Spaces :

Definition and examples of metric Space, neighborhood, limit points, interior points, open and Closed

sets, Closure, derived set and interior, boundary points. Continuity in metric space . Convergence and

completeness, Cauchys sequence completeness, Dense sets, Cantor sets [include Cantor set is Closed]

but [OMIT: - cantor set is compact and complete.]

Group Theory

UNIT 2: 25 marks

[a] Definition of Binary Operation, Properties of B. O. & examples, Group and its Properties, Examples

of Group, Subgroup & its properties, cosets & its properties, Lagranges theorem.

[b] Permutation, Transposition, Even & Odd Permutation, Symmetric Group, Inverse of Permutation,

Alternative Group & its Universal property.

[c] Cyclic Group &Cyclic Subgroup &its properties, Deduction of Lagranges Theorem. Definition of

Isomorphism, Equivalence Relation.

[d] Cayley Theorem, Automorphism, Properties of Isomorphism, Normal subgroup and quotient group.

Abstract Algebra, By: Dr. I. H. Sheth,Prentice Hall of India,New Delhi.

PROGRAMMING IN C (THEORY)

UNIT 1: 25 marks

[a] History of C, C character set, Constants, Variables, Keywords, Type Declaration, Type Conversion,

Hierarchy of operators, printf & scanf functions, If statement, if else statements, Nested if-else,

Logical operators, Conditional operators.

[b] While loop, for loop, do while loop, break statement, Continue Statement, goto statement,

Introduction to User Defined functions (see chapter 9 of Balaguruswamy for UDF),

[Omit: - switch case statement Pointers, and Recursion]

[c] Data types in C Integers: long and short types, signed and unsigned characters, signed and unsigned

Float and doubles, C processors, meaning, Only Macro Expansion, Macros with Arguments,

[OMIT: - File inclusion and various directives Conditional Compilation #if and #elif

Directives Miscellaneous Directives #undef Directive & pragma Directive.]

[d] Arrays, meaning: one dimensional and two dimensional, only Initialization and use in simple use in

programs. [OMIT: - no pointers and no three dimensional array, Arrays And functions. ]

NUMERICAL ANALYSIS- 1

UNIT 2: 25 marks

[a] Simultaneous linear algebraic equation:

Direct methods: Gauss elimination method, Gauss Jordan method, Method of factorization (L. U.

Decomposition), Crouts method.

Iterative methods: Jacobis method, Gauss Seidals method

BSc Syllabus 2017-18 Semester V&VI Mathematics

The linear law, Laws reducible to linear laws, Principle of least Square, Fitting a straight line, a

parabola and exponential curve and the curve y = axb

[c] Finite differences:

Finite differences (forward, backward and central), Differences of polynomials, Factorial polynomial,

Reciprocal Factorial polynomial, Polynomial factorial notation, Error Propagation in difference table,

other difference operators (Shift, Averaging, differential and unit) and relation between them.

[d] Interpolating with equal intervals:

Gregory Newton forward interpolation formula, Gregory- Newton backward interpolation formula,

Equidistance terms with one or more missing values.

Text Book for MATHEMATICS PAPER 502(A) :- (Theory)

Unit-1: PROGRAMMING IN C is as follows:

LET US C By : Yashvant Kanetker 5th Edition, BPB Publications New Delhi.

Unit 2: The scope of the syllabus is roughly indicated as under:

Numerical methods by Dr. V. N. Vedamurthy & Dr. N. Ch. S. N. Iyengar, Vikas Publishing house.

DISCRETE MATHEMATICS

UNIT 1: 25 marks

[a] Relations and different types of relations. Binary relations, Equivalence relations and partitions, partial

order relations, Posets, Hasse diagram, Lattices as posets, Properties of lattices , Lattices as algebraic

systems , sublattices , Direct product of two lattices, Homomorphism, , order isomorphism of two posets,

Isomorphic lattices, Complete lattices, Distributive lattices, Complemented lattices.

[b] Boolean algebra:

Definition, Examples BA, Direct product of two BA, homomorphism , atoms of BA , Anti atoms,

Stones representation theorem, The set A (x) of all atoms of BA and its properties. Isomorphism of

a finite of finite BA and (P (A), ), Boolean functions/ expressions, Minterms, Maxterms,

Representation of a B. expression as a sum of product canonical form, Karnaugh map. Minimization of

a B. expression by cube array representation and by Karnaugh map.

COMPLEX ANALYSIS 1

UNIT 2:

[a] Analytic functions:

Functions of complex variables, limits, theorems on limits, Continuity and differentiability of complex

functions, harmonic Functions, Entire functions and analytic functions, Cauchy Riemann conditions in

Cartesian and polar form.

[b] Definite integral contours, line integrals Cauchy Goursat theorem (without proof) , Cauchys integral

formula, Higher order derivative of analytic function, Moreras theorem, Cauchys inequality and

Liouvilles theorem, Fundamental theorem of algebra, Maximum modulus theorem.

Text Book of Mathematics Paper 503 section 2

Complex analysis 1:

Complex Variables and Applications,Fifth Edition, Rul V. Churchill and James Ward Brown.

Mc Graw Hill Publishing Company.

Numerical Analysis-1

Pr. No. (1) Fitting (1) a straight line and (2) y = eax

Pr. No. (2) Fitting (1) a parabola and (2) y = axb

Pr. No. (3) Gauss elimination

Pr. No. (4) Gauss Jordan method [OMIT: Triangularisation method and Crouts method.]

Pr. No. (5) Jacobis method

Pr. No. (6) Gauss Seidels method [OMIT: Relaxation method]

Pr. No. (7) Finite differences.

Pr. No. (8) Gregory Newtons forward Interpolation formula.

Pr. No. (9) Gregory Newtons backward Interpolation formula.

Pr. No. (10) Equidistance term With one or more missing values.

BSc Syllabus 2017-18 Semester V&VI Mathematics

PROGRAMMING IN C

Pr. No. (2) To write a program to find sum of the digits.

Pr. No. (3) To write a program to find prime number between two numbers,

Pr. No. (4) To write a program to find nPr and nCr.

Pr. No. (5) To write a program to print Armstrong numbers,

Pr. No. (6) To write a program to generate arithmetic and geometric progressions.

Pr. No. (7) To write a program to find compound interest for given years

Pr. No. (8) To write a program to find net Salary of the employee.

Pr. No. (9) To write a program to solve the quadratic equation,

Pr. No. (10) To write a program to find number of odd number and even numbers.

Pr. No. (11) To write a program to add and multiply two matrices.

Pr. No. (12) To write a program to solve the equation by Bisection method

Pr. No. (13) To write a program to solve the equation by N R Method.

Pr. No. (14) To write a program to verify a number whether it is palindrome or not.

PROGRAMMING with SCILAB

Pr. No. (1) To find the inverse of a matrix using Gauss-Elimination method

Pr. No. (2) To find the inverse of a matrix using Gauss-Jordan method

Pr. No. (3) To find Eigen values and eigen vectors of given matrix

Pr. No. (4) To find the inverse of a matrix using cayley hamilton theorem

Pr. No. (5) To solve given system of simultaneous linear algebraic equations using Gauss-Jordan method

Pr. No. (6) To solve given system of simultaneous linear algebraic equations using Gauss-Jacobi method

Pr. No. (7) To solve given system of simultaneous linear algebraic equations using Gauss-Seidal method

Pr. No. (8) To draw graphs of cycloid

Pr. No. (9) To draw graphs of catenaries

Pr. No. (10) To draw graphs of spiral r=exp(-theta/10)

SEMESTER VI

paper- 601(A) (Theory) GRAPH THEORY AND COMPLEX ANALYSIS

Graph Theory :

Unit 1:

[a] Graph theory (25 marks)

Basic definitions and simple examples, Directed, Undirected , multi graph, mixed graph. Incidence relation

and degree of the graph. Empty, complete, regular graphs .Sub graph, connected and disconnected graphs.

Walk and unilateral components ,Euler graphs, Unicursal graph, Operation of graph circuit and tree

.Hamiltonian path and cycles, tree, Binary and spanning trees

[b] Cut set ,connectivity and separability : (OMIT: 1-isomorphism,2-isomorphism)

Planar graphs and their different representation , Dual of a planar graph ,Eulers formula , Kuratowskis

first and second non-planar graph, vector space associated with a graph , Circuit subspace and cut sets

subspace , Orthogonal space.

Vertex coloring , Chromatic number ,Index number and partition , Cyclic graph and demyelization of cyclic

graphs , Matrix representation of a graph, Adjacency matrix, Incidence matrix, Path matrix

(OMIT: circuit matrix ,fundamental circuit matrix and cut set matrix, relationship of these matrices ,rank

of the adjacency matrix)

Complex Analysis-2

Unit 2 :

[a] Power series: (25 marks)

Definition of complex sequence, complex series and power series. Expansion of complex function in

Taylors series and Laurents series.

Mapping and Conformal mapping:

Elementary functions, mapping by elementary functions , mobius mapping, linear function. Bilinear

2 1

mapping w= (az+b)/(cz+d) ,w=z , w= ,w=exp(z)

z

(OMIT : w=sin z, w=cos z , w=coshz ,w=sinhz transformations, conformal mappings and their

examples)

BSc Syllabus 2017-18 Semester V&VI Mathematics

Definition of a singular point, Isolated singular points, Zeros of complex functions, Poles and residues of

complex function, Cauchys residue theorem, Evaluation of improper real integrals by residue theorem

and evaluation of definite integral of trigonometric functions by residue theorem

Text book for Mathematics PAPER BSMT - [601]:

Graph theory:

Graph theory with application to Engineering and Computer science, By- Narsingh Deo, Prentice Hall

of India Private Limited, New Delhi

Complex Analysis-2:

Complex Variables and Applications (fifth edition), By-Ruel V. Churchill and James Ward Brown, Mc

Graw-Hill Publishing Company

References:-

2. Theory of functions of a complex variables by Shantinarayan, Chand & Co.

3. Complex variables, Introduction and applications, by Mark Ablowitz and A.S. Fokas, Cambridge

University Press.

4. Graph theory with application to engineering and computer science by Narsingh Deo.1993, Prentice Hall of

India Pvt. Ltd.

5. Foundation of Discrete Mathematics, K.D. Doshi, New Age International Ltd. Publishers.

6. A first look at Graph theory, by Clark.

7. Discrete Mathematics Structures with application to computer science, by Trembly I.P & Manohar R.

8. Elements of Discrete Mathematics (2nd Edition) by L.Liu, Me.

9. Discrete Mathematics, by Vasta, Vikas Publications.

10. Introduction Graph Theory, By R.J.Willson

11. Discrete Mathematics Structure, By. Dugragi N.

Analysis -2

Unit 1: (25 marks)

a) Cover, Open cover, Finite sub cover , Compact set ,Properties of compact sets, Connected sets, separated

sets, Bolzano-Weistrass theorem, Countable set

b) Continuity and uniform continuity ,isometry and homomorphism of two metrics, Equivalent metrics,

compactness, sequential compactness, totally bounded space

c) Laplace Transforms

Definition of Laplace Transforms. Laplace Transforms of elementary function. Inverse Laplace

Transforms. Laplace Transforms of derivatives and integrals, Differentiation and integration of Laplace

Transforms. Convolution Theorem (Omit: Application to differential Equations)

Abstract Algebra -2

[a] Homomorphism, Kernel of homomorphism, Fundamental theorem of homomorphism, Ring and its

properties, Sub Ring (Omit: Boolean ring, Euclidean ring)

[b] Field, zero divisor, Integral domain , Characteristics of ring, Cancellation law. Ideals, principal ideal,

polynomial ring, (Omit: Quotient ring, Maximal ideal), Polynomial, Degree of polynomial, Factor and

remainder theorem of polynomial, Product, sum and division of polynomials

[c] Reducible and irreducible polynomials, Factorization of polynomials , unique factorization theorem

(without proof) (Omit: Eisensteins criterion), Division algorithm theorem of polynomials

[d] G.C.D. of polynomials, Quaternion (Omit : Ring homomorphism, Euler and Fermats theorem)

Analysis 2

For Laplace Transfoms

Advanced Mathematics for pharmacy Mahajan publishing House, Ahmedabad

Text book for Mathematics Paper BSMT 602(A)

Abstact algebra By- Dr. I.H.Sheth, Precntice Hall of India ,New Delhi

References:

1. Topics in Algebra, I.N. Herstein, Willey Eastern Ltd. New Delhi

BSc Syllabus 2017-18 Semester V&VI Mathematics

2. A text Book of Modern Abstract Algebra, by Shantinarayan, S. Chand & Co., New Delhi.

3. Fundamental of Abstract Algebra, D.S. Malik, J. N. Mordoson and M.K.Sen, McGraw Hill

International Edition-1997.

4. University Algebra, M.S. Gopalkrishna, Wiley Eastern Ltd.

5. Abstract Algebra, By Bhattacharya , Yallo Publications.

6. Modern Algebra, Kazi zamiudia & Sursit, Vikas Publication , Delhi.

7. Text Book : Abstract Algebra, Dr. I.H. Sheth, Nirav Prakashan, Ahmedabad.

8. Mathematical Analysis (2nd edition) by S.C. Malik & Arora, New Age Inter, Pvt.

9. Mathematical Analysis, By T. M. Apostol

10. Real Analysis, By R.R. Goldberg (Chap 4,5,6,7,9 & 10.1)

11. A course of Mathematical Analysis, by Shantinarayan, S. Chand & Sons.

12. Metric Space by E. T. Capson

13. Metric Space, P.K.Jain & Ahmad, Naroa Publishing House.

14. Real Analysis by Sharma and Vasishtha Krishna Prakashan , Meerut-2.

15. Mathematical Analysis by Dr. Goyal and Gupta , Krishna Prakashan ,Meerut-2

Optimization

[a] The linear programming problems , Formulation of LPP , Matrix form of the LPP, general form, Canonical

form, Standard form of the LPP ,Graphical method to solve LPP, Some definitions and basic properties of

convex sets, convex functions and concave functions. Basic definitions to use Simplex method, Simplex

method, Big M method (Penalty method), Two phase method to solve LPP (Without alternative solution and

unbounded solution)

[b] Principle of duality in LPP, Primary LPP and method to find its dual LPP (simple problems of above articles).

The transportation problems: Mathematical and matrix form of TP, Initial solution of TP by NWCM ,

LCM and VAM, Optimum solution of TP by Modi method (u-v method) (except degenerate

solution),Balanced and unbalanced TP (Simple problem),

Assignment problem: Mathematical and matrix form of AP, Hungarian method to solve method (simple

method)

Numerical Analysis -2

Unit 2 [25 marks]

a) Central difference interpolation formulae:

Gauss forward ,Gauss backward , Sterlings , Bessels and Laplace Evettes interpolation formulae

b) Interpolation with unequal intervals:

Divided differences, properties of divided difference, Relation between divided differences and forward

difference, Newtons divided difference formula, Lagranges interpolation formula, Inverse

interpolation, Lagranges inverse interpolation

c) Numerical Differentiation:

Numerical Differentiation, Derivatives using Gregory- Newtons forward difference formula, Derivatives

using Gregory- Newtons backward difference formula, Derivative using Sterlings formula

d) Numerical Integration

Numerical Integration, General quadrature formula, Trapezoidal rule, Simpsons 1/3 rule, Simpsons 3/8

rule, Weddles rule and errors in quadrature formulae

e) Numerical solution of ordinary differential equations

Solution by Taylors series method, Taylors series method for simultaneous first order differential

equations, Picards method, Picards method for simultaneous first order differential equations, Eulers

method ,Improved Eulers method, Modified Eulers method

f) Runges method,Runge-kutta methods, Higher order Runge-kutta methods, Runge- kutta methods for

simultaneous first order differential equations, Predictor- connector methods, Milnes method

Text book for Mathematics BSMT- 603(A) (Theory)

OPTIMIZATION

Operation Research theory and Application J.K.Sharma, second edition, Macmillan India Ltd

Text book for Mathematics Paper 603(A)

NUMERICAL METHODS

BSc Syllabus 2017-18 Semester V&VI Mathematics

Reference Books :

Introduction to Numerical Analysis (2nd Edition) by C.E. Froberg Addision Wasley, 1979.

1.

2.

Numerical Mathematical Analysis by J.B. Scarforough , Oxford & IBH Publi. Co. Pvt. Ltd.,1966.

3.

Numerical method, Problems & Solutions , by M.K. Jain, S.R. Iyengar , R.K. Jain, New Age

International Pvt. Ltd.,1996.

Mathematics paper- 601(B) (PRACTICAL)

Introduction to SAGE

Pr. No. 1 : Introduction to SAGE:

i.e. Introduction to variables , constants, data types, some inbuilt(library) constants and functions, how

to enter a matrix , how to enter a vector, operators, how to get help etc.

Pr. No. 2 : Operations on expressions :

(b) Solve ([f(x,y)==0,g(x,y)==0],x,y)

(c) Find a root of f(x) in the given interval [a,b] such that f(x) 0(approximate root)

(d) Finding sum and product of the given series from 1 to n terms (using sum() And prod() functinons)

(b) Find left and right hand side limits of a given function

(c) Find the derivative of a given function.

(d) Find maxima and minima of a given function f(x) in the given interval (a, b).

(e) Find the partial derivative of a given bi-variate function.

(f) Find the indefinite integral of a given function.

(g) Find the definite integral of a given function.

(h) Find numerical integral of a given function.

(i) Find Taylor series expansion of a given function f(x) about x=a upto degree n.

(b) Draw a polygon having the given points as its vertices.

(c) Draw a circle with the given point as center and with the given radius.

(d) Plotting the graph of a given function f(x).

(e) Draw the graph of the function f(x) (given in parametric form)

(f) Drawing graph of the function. (in polar form)

(g) Drawing combine graphs.

(h) Drawing graphs with animation.

(i) Using options in plotting 2D graphs.

(b) Draw a sphere with the given point as center and with the given radius.

(c) Drawing Platonic solids (tetrahedron, cube, octahedron, dodecahedron, icosahedrons).

(d) Draw the graph of given function f(x,y) in 3D.

(e) Draw the graph of given function f(x,y) in 3D (Parametric Form)

(f) Using options in plotting of 3D graphs.

Pr. No. 6 : Simplification and expansion of a given symbolic function:

BSc Syllabus 2017-18 Semester V&VI Mathematics

(c) To determine whether the entered matrix is square, zero, identity, scalar, Symmetric , invertible,

nilpotent, idempotent or not.

(d) Entering a square matrix and finding its inverse if exists.

(e) Finding rank, nullity no. of rows , no. of columns , trace, transpose of a given Matrix.

(f) Finding Echelon form of the entered matrix.

(g) Finding characteristic polynomial, eigen values and eigen vectors of the entered matrix.

(h) Performing row operations on the entered matrix.

(b) Find the next prime, previous prime next probable prime to the entered number.

(c) Finding primes p such that m p n .(using prime_range(m,n))

(d) Finding prime powers (using prime_powers(m,n))

(e) Finding continued fractions of x.

(b) Abelian group, Matrix groups (GL = General Linear Group and SL= Special Linear group), normal

subgroups

(c) Drawing graphs with given vertices and edges.

(d) Chromatic polynomial of graph G.

(e) Testing planarity of graph.

(f) Finding Shortest Path in a graph.

NUMERICAL ANALYSIS - II

Pr. No. 2 : Gauss backward interpolation formula

Pr. No. 3 : Sterlings or Bessels formula

Pr. No. 4 : Laplace- Everetts formula

Pr. No. 5 : Interpolation with unequal intervals

Pr. No. 6 : Numerical differentiation

Pr. No. 7 : Numerical Integration

Pr. No. 8 : Taylors or Picards Method

Pr. No. 9 : Eulers method

Pr. No. 10 : Runges method

Pr. No. 11 : Runge Kutta s method

Pr. No. 12 : Milnes method

OPTIMIZATION

Pr. No. 2 : Solve the following LPP using Simplex Method

Pr. No. 3 : Solve the following LPP using Big M Method

Pr. No. 4 : Solve the following LPP using Two Phase Method

Pr. No. 5 : Obtain dual of the following LPP

Pr. No. 6 : Find the initial solution of a given transportation problem using NWCM method

Pr. No. 7 : Find the optimum solution of the following Transportation problem using LCM method

Pr. No. 8 : Find the optimum solution of the following Transportation problem using VAM method

Pr. No. 9 : Find the optimum solution of the following Transportation problem using MODI method

Pr. No. 10 : Find the optimum solution of the following Assignment problem

BSc Syllabus 2017-18 Semester V&VI Chemistry

CHEMISTRY

SEMESTER V

[C-501]INORGANIC CHEMISTRY & INDUSTRIAL CHEMISTRY

Unit-I: Inorganic Chemistry [40 Marks]

1. Wave Mechanics

Outline of basic concepts of wave mechanics(Sem-III)

Operators algebra (addition, subtraction, multiplication), commutative property, linear operator,

commutation operator, the operator DEL & DEL SQUERED, momentum operator, Hamiltonian operator

Particle in one dimensional box; normalized wave equation and energy related to a particle moving in

one dimensional box, energy levels and interpretation of energy equation, linear polymers as one

dimensional box, examples.

Particle in three dimensional box : Derivation of normalized wave equation, energy related with it,

energy levels and degeneracy, examples.

Wave equation for hydrogen atom: To derive the relation between Cartesian and polar coordinates,

derivation of volume element in polar coordinates, Schrodinger equation in polar coordinates, separation

of variables.

Energy of 1s orbital, normalization condition and problems on it (in polar coordinates).

2. Crystal Field Theory-1

Introduction

Concept of crystal field theory

Splitting of d-orbitals in octahedral and tetrahedral crystal field with CFSE concept.

Factors affecting splitting energy.

Weak field and strong field ligands.

High spin and low spin complexes with pairing energy.

Magnetic behaviour of transition metal complexes.

Orbital angular momentum contribution to magnetic momentum of complexes.

Examples based on CFSE, Pairing energy and magnituc momentum.

3. Transition metal complexes of - acid ligands

Metal carbonyls: Definition, preparation, physical and chemical properties, nature of M-CO linear bond

based on M.O. Theory with spectral support, classification of metal carbonyls, types of CO groups and

detection of CO groups using IR spectra.

Structure of Ni(CO)4,Fe(CO)5,Fe2(CO)9,Co2(CO)8,Fe3(CO)12 and Mn2(CO)10

Metal nitrosyls.

List of Reference Books (Inorganic Chemistry) :

(1) Quantum Chemistry R.K. Prasad, New Age International Publishers

(2) Inorganic Chemistry- James E Huheey (3rd Edition) Harper International SI Edition

(3) Coordination chemistry Gurdeep Chatwal and MS Yadav, Himalaya publishing House

(4) Principles of Inorganic Chemistry B.R.Puri, L.R. Sharma & K.C. Kalia; Vallabh Publications, Delhi

(5) Modern aspects of Inorganic Chemitry- H.J. Emeleus and A.G. Sharpe; Routledge & Kegan Paul Ltd.,

39 Store street, London WCIE7DD

(6) Advance Inorganic Chemistry (3rd Edition)- F.A. Cotton and G. Wilkinson; Wiley Eastern Pvt. Ltd.

Unit-II: Industrial Chemistry [35 Marks]

1. Cement

Introduction

Type of cement

Raw material for manufacture

Cement rock benefication

Manufacturing Processes

(a) Dry Process (b) Wet Process

Setting and hardening of cement

(a) Hydrolysis (b) Hydration

Properties of cement

Indian Standard Institute (ISI) specification of cement

Mortar, concrete and RCC

BSc Syllabus 2017-18 Semester V&VI Chemistry

Uses of cement

2. Fertilisers

Introduction

Plant nutrients and its role

Classification of fertilisers

Properties of fertilisers

Nitrogenous fertilisers

Ammonium nitrate

(a) Manufacture by Prilling method

(b) Manufacture by Stengel method

Ammonium sulphate

(a) Manufacture from gypsum (Sindri Process)

(b) Action as fertiliser

Urea

(a) Manufacture from ammonium carbamate

(b) Action as fertiliser

Calcium cyanamide

(a) Manufacture by electric carbonate

(b) Action as fertiliser

Phosphate fertiliser

Normal super phosphate

Manufacture

Triple super phosphate

Manufacture

Ammonium Phosphate

(a) Manufacture of mono ammonium phosphate

(b) Manufacture of diammonium phosphate

Potassium fertilizer (K2SO4 & KNO3)

NPK fertiliser

Nomenclature

3. Petrochemicals

Introduction

Petrochemicals from Methane (C1), Ethylene (C2) and Propylene (C3)

Methane

(a) Manufacture of Chloromethanes (Chlorinated hydrocarbons)

(b) Manufacture of Synthetic gas

Ethylene

(a) Manufacture of ethylene glycol from

(1) Ethylene chlorohydrins

(2) Ethylene oxide

(b) Manufacture of ethyl alcohol by

(1) sulphuric acid process and

(2) catalytic hydration process

Propylene

(a) Manufacture of glycerol

(1) via allyl chloride and

(2) via acrolein

(b) Manufacture of acrylonitrile

List of Reference Books (Industrial Chemistry) :

1. A Text Book of Petrochemicals by Bhaskar Rao

2. Advanced Petrochemicals by Dr. G.N. Sarkar

3. Chemicals from Petrochemicals by A.L. Waddam

4. Reigels Handbook of Industrial Chemistry by James A. Kent

BSc Syllabus 2017-18 Semester V&VI Chemistry

6. Outlines of Chemical Technology by Charles Dryden

7. Industrial Chemistry by B.K. Sharma

[C-502]ORGANIC CHEMISTRY & SPECTROSCOPY

Unit-I: Organic Chemistry [40 Marks]

1. Name Reactions, Rearrangement and Reagents:

Reactions

a. Arndt Eistert Reaction

b. Bischler Napierski Reaction

c. Leuckart Wallach Reaction

Rearrangements

a. Hoffmann Rearrangement

b. Curtius Rearrangement

c. Fries Rearrangement

Reagents

a. Lithium Aluminium Hydride LiAlH4

b. Triphenyl phosphine

c. Sodamide

2. Alkaloids

Introduction, Occurrence, Classification, Isolation, General method of proving structure of Alkaloids,

Constitution, Properties and Synthesis of:

a. Coniine

b. Nicotine

c. Papaverine

3. Carbohydrates

Introduction, Classification and nomenclature, General reactions of Monosaccharides (with reference to

Glucose and Fructose)

Inter-conversions:

a. Conversion of Aldose to the corresponding Ketose

b. Conversion of Aldose to the next higher Ketose (Wolform method)

c. Conversion of Aldose to the Ketose having two more carbon atoms (Sowden method)

d. Conversion of Ketose to the corresponding Aldose

Step-up reactions (Ascending in Aldose series)

a. Kiliani Reaction

b. Swoden Nitromethane reaction

Step-down reactions (Descending in Aldose series - Aldohexose to Aldopentose) by Ruffs Method

Configuration of monosaccharides

Ring structure of Aldoses

Determination of ring size of Glucose by

a. Methylation method

b. Periodic oxidation method

Mutarotation of D (+) glucose

4. Synthetic Drugs, Dyes and Sweetening Agents

Only Synthesis and Uses of

Drugs: Ibuprofen, Atenlol and Adrenaline

Dyes: Orange II, Crysodine G, Auramine O

Sweetening Agents: Saccharin, p-anisylurea and Dulcin

5. Synthesis of Heterocyclic Compounds containing two hetero atoms

Preparation of:

1) Pyrazole

2) Imidazole

3) Isoxazole

4) Thiazole

5) Pyrimidine

6) Pyridazine

7) Oxazine

BSc Syllabus 2017-18 Semester V&VI Chemistry

8) Thiazine

9) Dioxane

Unit-II: Spectroscopy [35 Marks]

1. Molecualr symmetry

Introduction,

symmetry elements and symmetry operation with illustration

Definition of Properties of group , subgroup and classes

Products of symmetry operations

symmetry point group.C1, Cs, Ci, Cn, Cnv, Cnh, Dn, Dnh, Dnd, C, Dh, Td, Oh

Multiplication tables for C2v , C3v and C2h point groups. (Point Group are given in separate page )

2. U.V. spectroscopy

Introduction

Theory of ultra violate spectra

Instrumentation

Type of transition in organic molecules ; auxochrome, chromophore ;

Explanation of bathochromic shift and hypsochromic shift,

Hyper chromic effects

Types of bands

Effect of solvent, franck condon principles

Application of UV spectra

Calculation of -max (1) Dienes and conjugated dienes (2) enones and dienones ie. unsaturated carbonyl

compounds, (3) aromatic carbonyl system

3. Infra red Spectroscopy

Introduction

Range of IR , theory of IR

Modes of fundamental vibration

IR active, force constant

Vibration coupling

Fermi resonance

Finger print region

Instrumentation

Application of IR

Structure of organic molecules From IR

Interpretation of IR for given molecules and problems

Reference Books (Spectroscopy) :

(1) Spectrometric identification of organic compounds

By Silverstrin Bassler (16th Editim)

(2) Elementary organic spectroscopy by Y. R. Sharma.

(3) Spectroscopy of organic compounds by John R. Dyer.

(4) Spectroscopy of organic compounds by P. S. Kalsi

(5) Chemical Application of Group theory by F Albert Cotton

(6) Symmetry in chemistry by H. M. Jahe.

(7) Molecular spectroscopy by B. K. Sharma.

(8) Organic Spectroscopy by B. K. Sharma

1. Second Law of Thermodynamics

Limitation of first law of thermodynamics

Spontaneous process

Carnot cycle and theorem

Statements of second law of thermodynamics

Perpetual motion of second kind (briefly)

Concept of entropy, Definition of entropy

BSc Syllabus 2017-18 Semester V&VI Chemistry

S in ideal gases

S of mixture of ideal gas

S in physical transformations

Entropy and second law of thermodynamics

Physical significance of entropy

Work function: its physical significance and variation with V and T

Free Energy: its significance and variation with P and T

G for ideal gases, Gibbs Helmholtz equation and its applications

Criteria for chemical equilibrium

Vant Hoff reaction isotherm

Vant Hoff isochore

Law of active mass

Clausius Clapeyron equation

3. Crystalline State

Difference between crystalline and amorphous solid, Crystal and crystallography

Three laws of crystallography

Structure of crystals

Space lattice and Unit cell, Bravice lattices

Type of cubic lattice and inter planar spacing

X- rays Diffraction: Brags equation, Experimental methods (Rotating crystal and Powder method),

Structure of Rock salt (NaCl) and Sylvin (KCl)

Liquid Crystals: Introduction, Definition and Classification of liquid crystals (Smectic, Nematic,

Cholesteric and Disc shaped)

4. Phase Rule

Three component system,

Method of graphical presentation,

Types of partially miscible three liquid systems:

(1) One partially miscible pair: (Effect of adding third compenent, Nature of tie line, Plait point, Binodle

curve, Characteristics of diagram, A is added to binery system, A is constant and B and C varied,)

(2) Formation of two pairs of partially miscible liquid,

(3) Formation of three pairs of partially miscible liquid.

Application of ternary liquid diagram

Reference Books (Physical Chemistry):

(1) Elements of Physical Chemistry, S Glasstone and D Lewis, Macmillon and Co Ltd., New Delhi.

(2) Principles of Physical Chemistry , S H Maron and C F Prutton, Oxford and IBH , New Delhi.

(3) Thermodynamics for Chemists, S Glasstone, Affiliated East West Press Pvt Ltd, New Delhi

(4) Elements of Physical Chemistry, B R Puri, L R Sharma, M S Pathania Vishal publishing Co Jalandhar.

(5) Advanced Physical Chemistry, J. N. Gurtu, Pragati Prakashan, Meerut.

(6) Physical Chemistry, N. Kundu and S. K. Jain, S. Chandand Co. New Delhi

(7) Physical Chemistry, K. L. Kapoor, Macmillan India Ltd. Delhi.

(8) Physical Chemistry, B. K. Sharma Goel Publishing House, Meerut.

(9) Thermodynamics, Dr. Gurdeep Raj, Goel Publishing House Meerut

Unit-II: Analytical Chemistry [35 Marks]

1. Errors and statistics

Introduction

Explanation of errors and mistakes.

Classification of errors, determinate and indeterminate errors, operational and personal error,

Instrumental errors and reagent errors, additive and proportional error

Accuracy and precision, minimization of error

Calibration of Instruments , blank measurement , independent method parallel method, standard

addition method

BSc Syllabus 2017-18 Semester V&VI Chemistry

Mean and standard deviation , variance and coefficient of variance

Absolute error and relative error , mean value , deviation and relative mean deviation. Gausian

curve and its explanation

Importance of Q test and T -test ( Student T test )

Example on errors, significant figures , Q test and T test

[2] Basic Principle of Qualitative analysis only separation

(1) Cl, Br , I (2) NO2 , NO3 , Br

(3) S2 , SO3 -2 , SO4-2 (4) PO4-3 , As O3-3, AsO4-3

(5) CO3-2 , SO3-2 , S-2 (6) Cu+2 , Cd+2

[3] Colourimetry

Introduction

Growth Drapper law, Lamberts Law, Beayers Law,Lamberts & Beayers Law and Derivation,

application and deviation of Lamberts Law

Spectro photometric titration with graph and proper explanation

(1) Deficit of absorbance by product and Titrant

(2) Deficit of absorbance by product and Reagent

(3) Deficit of absorbance by Reagent and Titrant

(4) Deficit of absorbance by product only

[4] Volumetric analysis with example of calculation based on pH, normality, molarity, Ksp etc.

Ostwalds law- Regarding indicator necessary derivation and formula of indicator used in

Neutralization, redox ,precipitation titration.

Primary and secondary standard explanation

(1) Explanation of neutralization titration with graph.

(i) Strong acid - Strong base titration

(ii) Weak acid - Strong base titration

(iii) Strong acid Weak base titration.

(iv) Poly protic acid - Strong base titration

(2) Redox titration :

Principle of external and internal indicator in redox titration. e.g. Diphenyl amine , starch

& K3[Fe(CN)6]

Redox Titration with graph and calculation

Iodometry and Iodimetry titration

Preparation of standard sodium thiosulphate solution

(3) Precipitation Titration :

Argentometric Titration (I) Mohars method (II) Fazans method (III) Olhards method

with use of proper indicator, graph and its practical application

Examples of calculation based on pH, Normality, Molarity,Ksp etc

Reference Books (Analytical Chemistry) :

(1) Fundamental of analytical chemistry by skoog & west

(2) Instrumental method of chemical analysis By B. K. Sharma 22 wilhim

(3) Water analysis and nater pollution by V. P. Kudesia

(4) Instrumental method of chemical analysis By Chatwal Amreli

(5) Thin layer chromatography by Egal stall

(6) Book for water analysis: By R.K. Trivali, V. P. Kulesiya.

(7) Analysis cal chemistry by click

(8) Inorganic inflictive analysis by Vogel and Gehani Parekh

(9) Electronic methods of analysis by brewing

(10) Principle of instrumental analysis by S korg.

BSc Syllabus 2017-18 Semester V&VI Chemistry

(1) Organic Separation ( Mixture of two compounds ) [30 marks]

[Minimum 12 mixtures should be done]

Separation & Analysis of an organic mixture containing:

(a) Two solid components using water, NaHCO3, NaOH and HCl for separation

(b) Liquid + liquid component - separation by physical method.

(c) Liquid + solid component - separation by physical method.

(2) Inorganic Volumetric Analysis [20 marks]

[Minimum 8 exercises should be done]

For volumetric exercise all the standard solutions are to be prepared by the students.

(i) Iodometry and Iodimetry

a. Estimation of Cu+2 and CuSO4.5H2O in the given CuSO4.5H2O using 0.05N Na2S2O3.5H2O

solution.

b. Estimation of As+3 and As2O3 in the given As2O3 using 0.05N Na2S2O3.5H2O solution.

(ii) Complexometric titration:

1. Estimation of the amount of Ni+2 in the given NiSO4.7H2O solution using 0.02 N EDTA

solution.

2. Estimation of the amount of Mg+2 and Pb+2 in the given solution containing a mixture of Mg+2

and Pb+2 using 0.02 N EDTA solution

3. Estimation of the amount of Ca+2 and Zn+2 in the given solution containing a mixture of Ca+2

and Zn+2 using 0.02 N EDTA solution

4. Estimation of the amount of Fe+3 and Cr+3 in the given solution containing a mixture of Fe+3

and Cr+3 using 0.02 N/ 0.01 M Pb(NO3)2 and 0.02 N/ 0.01 M EDTA solution.

(iii) Redox titration:

Determination of the amount of NO2-1 in the given NaNO2 or KNO2 solution by reduction

method using 0.1 N KMnO4 solution.

(iv) Water Analysis:

To determine the amount of chloride in the given sample of water using 0.02 N AgNO3

(v) To determine the purity of NaHCO3 in the given sample

[Minimum 12 exercises should be done]

Conductometry

1. To determine normality and gms/lit of xN HCl and also determine specific conductance by

conductometry.

2. To determine normality and gms/lit of the mixture of HCl+CH3COOH by conductometry.

3. To determine the normality of weak acid by conductometry.

4. To determine the concentration of Ni+2 using 0.1M EDTA solution.

5. To determine the normality of xNAgNO3 using 0.5N NaCl by conductometry.

pH metry

1. To determine normality of xN HCl by pH metry.

2. To determine normality and dissociation constant of weak acid (xN CH3COOH) by pH metry.

3. To determine normality and dissociation constant of dibasic acid (xN oxalic acid/malonic

acid/maleic acid) using 0.1N NaOH solution.

Colourimetry

1. Find out the amount of Ni+2 in the given solution by colourimetry method.

2. Find out the amount of Fe+3 in the given solution by colourimetry method.

Viscosity

1. To determine relative and absolute viscosity of pure liquid A, B, C, D by Ostwalds viscometer.

2. Prepare three different 10%, 5%, 2.5% aqueous solution of Glycerine. Find viscosity of these three

solutions as well as unknown concentration solution with the help Ostwalds viscometer.

Refractometer

1. To determine specific refractivity and molecular refractivity of given pure liquid A, B, C, D.

BSc Syllabus 2017-18 Semester V&VI Chemistry

2. To determine specific refractivity and molecular refractivity of glycerine (10%, 5%, 2.5%) and

unknown glycerine solution.

SEMESTER VI

Unit-I: Inorganic Chemistry [35 Marks]

1. Multi Electron System

Concept of spectral terms and term symbols.

s-s coupling, l-l coupling, l-s coupling, j-j coupling and L-S coupling with vector diagram.

Derivation of spectral term symbol for P1,P2,P3,&d1 to d9.

Micro states: definition, calculation and derivation of microstates for p1,p2,d1&d2 (pegion hole diagram).

Hund,s rules for the determination of ground state spectral term.

Jahn-Teller effect: Statement and explanation.

Tetragonal distortion with example.

Splitting of d-orbitals in square planar complexes with examples.

Hole formalism.

Splitting of D and F ground terms(using hole formalism).

Orgel Diagram of D and F states.

Selection rules for d-d transition.

Types of electronic transition in metal complexes.

Absorption spectrum of Ti +3,Cu +2 & Ni +2.

3. Magneto Chemistry

Introduction (Magnetic field, Magnetic pole, Intensity of magnetization).

Magnetic induction.

Permeability, intensity of magnetism, magnetic susceptibility, molar magnetic susceptibility.

Magnetic behaviour : Diamagnetism, Paramagnetism, Ferro magnetism and Antiferro magnetism.

Effect of temperature on magnetic behaviour of substances.

Derivation of equation for total angular magnetic momentum and diamagnetic momentum.

Determination of magnetic susceptibility by Gouy method.

Reference Books:

(1) Quantum Chemistry R.K. Prasad, New Age International Publishers

(2) Inorganic Chemistry- James E Huheey (3rd Edition) Harper International SI Edition

(3) Coordination chemistry Gurdeep Chatwal and MS Yadav, Himalaya publishing House

(4) Principles of Inorganic Chemistry B.R.Puri, L.R. Sharma & K.C. Kalia; Vallabh Publications,

Delhi

(5) Modern aspects of Inorganic Chemitry- H.J. Emeleus and A.G. Sharpe; Routledge & Kegan Paul

Ltd., 39 Store street, London WCIE7DD

(6) Advance Inorganic Chemistry (3rd Edition)- F.A. Cotton and G. Wilkinson; Wiley Eastern Pvt. Ltd.

UnitII : Industrial Chemistry [40 Marks]

1. Glass

Introduction

Physical and chemical properties of glass

Raw materials for manufacture

Chemical reactions involved

Method of manufacturing

o Formation of batch material

o Melting

o Shaping

o Annealing

o Finishing

Special types of glasses

BSc Syllabus 2017-18 Semester V&VI Chemistry

Fused silica glass, High silica glass, optical glass, borosilicate glass, lead glass, coloured glass, opal glass,

safety glass, fibre glass, glass wool, pyrex glass, photochromic glass, insulating glass, rare earth glass,

vitreosil, photosensitive glass.

2. Oil and Fats

Introduction

Distinction between oils and fats

Properties of fats and oils

Classification of fats and oils

Manufacturing of cotton seed oil

Expression method

Solvent extraction method

Refining of crude vegetable oil

Hydrogenation of oils

Optimum conditions for the process

Dry process

Wet process

Analysis of oils and fats

Saponification value

Acid value

Iodine value

Reichert Meissl (RM) value

3. Soaps and Detergents

Introduction to soap

Raw materials for manufacture

Methods for manufacture of soap

(a) Batch process

(b) Continuous process

Types of soap

Toilet soap, transparent soap, shaving soap, Neem soap, Liquid soap

Recovery of glycerine from spent lye.

Introduction to detergents

Principal group of synthetic detergents

Biodegrability of surfactants

Classification of surface active agents

Anionic detergents

Manufacture of anionic derergents

(a) Oxo Process

(b) Alfol Process

(c) Welsh Process

Cationic detergents

Manufacture

Non Ionic detergents

Manufacture by batch process

Amphoteric detergents

Manufacture of shampoo

4. Environmental Chemistry

Environment definition and introduction

Segments of environment

(a) atmosphere

(b) hydrosphere

(c) lithosphere

(d) biosphere

Air Pollution

Introduction

BSc Syllabus 2017-18 Semester V&VI Chemistry

Major sources of air pollution

Photochemical smog and acid rain

CFC and ozone depletion

Sources and effects of NOX and SOX

Control of Air pollution

Water pollution

Introduction

Classification of water pollution

(a) Physical pollution

(b) Chemical pollution

(c) Biological pollution

(d) Physiological pollution

Sources of water pollution

(a) Sewage and domestic waste

(b) Industrial effluents

(c) Agricultural discharges

(d) Fertilisers

(e) Toxic metals

(f) Siltation

(g) Thermal pollutions

(h) Radioactive materials

Water Pollution Control

Dissolved Oxygen (D.O.) determination

Chemical Oxygen Demand (C.O.D.) determination

Biological Oxygen Demand (B.O.D.) determination

Reference Books ( Industrial Chemistry):

(1) Environment Pollution Control Engineering by Rao C.S.

(2) Industrial Chemistry by B.K. Sharma

(3) Environmental Chemistry by A.K. De

(4) Environmental Solution of Analysis by S.M. Khopkar

(5) Engineering Chemistry by Jain & Jain

(6) Regiels Handbook of Industrial Chemistry by Jomes A. Kent

(7) Environmental Chemistry by Sharma & Kaur

(8) Outlines of Chemical Technology by Charles Dryden

Terpenoids

Introduction

Occurrence, Isolation, General characteristics of Terpenoids, Isoprene Rule

Constitution and Synthesis of :

a. Citral

b. -Terpineol

2. Amino acids, Peptides and Proteins

Introduction

Classification of amino acids name and formula

Synthesis of amino acids by:

a. Amination of -halogen acids

b. Gabriel pthalimide synthesis

c. Hofmann Degradation

d. Erlen-meyer azlactone synthesis

e. Hydantoin method

BSc Syllabus 2017-18 Semester V&VI Chemistry

Physical properties of amino acids, Chemical properties of amino acids, Isoelectric point

Introduction to Polypeptides

Synthesis of Polypeptides by:

a. Bergmann Method

b. Sneehans Method (use of Phthaloyl group)

c. Fischers Method (use of p-toluenesulphonylchloride)

Introduction and classification of proteins

Constitution of Thyroxine, Synthesis of Thyroxine

3 Synthetic Explosive, Perfumes and Insecticides

Synthesis and uses of :

Explosives :

a. RDX (Research Development Explosive)

b. TNT (Trinitrotoluene)

c. PETN (Pentaerythritol tetranitrate)

Perfumes :

a. Musk Xylene

b. Musk Ketone

c. Musk Ambrette

Insecticides :

a. Baygon

b. Carbendazin

c. Parathion

4. Polynuclear Aromatic Hydrocarbons

Introduction, Synthesis and chemical properties:

a. Biphenyl

b. Diphenyl methane

c. Naphthalene

d. Anthracene

5. Conformational Isomerism

Conformation of acyclic system

Conformational analysis of ethane

Conformational analysis of n butane

Conformation of cyclic system: Cyclohexane and cyclopentane

Conformational analysis of cyclohexane: Boat form and Chair form

Conformation of monosubstituted cyclohexane

(1) Synthetic Organic Natural Products (Volume I & II) by O.P Agrawal.

(2) A Text Book of Organic Chemistry (II Edition) by Raj K. Bansal

(3) Medicinal Chemistry by Ashutoshkar

(4) Pharmaceutical Chemistry by Axel Kleemann & Jugen Engel (IV Edition Thieme Stuttgart New York)

(5) Organic Name reactions by Gautam Brahmachari

(6) Chemistry of Alkaloids -University Granth Nirman Board Ahmedabad

(7) Reactions and Rearrangements by Gurdeep Chatwal

(8) Name Reactions in Organic Synthesis by Dr. A.R.Parikh et. al

(9) Organic Chemistry of Natural Products by Gurudeep Chatwal Vol L

1. NMR Spectroscopy

Introduction, principle

Nuclear quantum number

equivalent and nonequivalent protons with illustrations ; enantiomeric and diasteriomeric protons,

shielding and de shielding of protons;

Chemical shift

BSc Syllabus 2017-18 Semester V&VI Chemistry

Relative intensity of signals

Spin- spin coupling and coupling constant

Deuterium labeling

Application of NMR

Problems for determination of structure of organic molecules

2. Mass Spectroscopy

Introduction

Classification of spectroscopy origin and basic principles

Instrumentation

General fragmentation modes

Important future for the mass spectra of alkanes

3. Problems based on application of U.V. IR, NMR spectroscopy with empirical and molecular formula

Reference Books (Spectrosopy) :

(1) Spectrometric identification of organic compounds by Silverstrin Bassler (16th Editim)

(2) Elementary organic spectroscopy by Y. R. Sharma.

(3) Spectroscopy of organic compounds by John R. Dyer.

(4) Spectroscopy of organic compounds by P. S. Kalsi

(5) Chemical Application of Group theory by F Albert Cotton

(6) Symmetry in chemistry by H. M. Jahe.

(7) Molecular spectroscopy by B. K. Sharma.

(8) Organic Spectroscopy by B. K. Sharma

Unit-I : Physical Chemistry [35 Marks]

1. Third Law of Thermodynamics

Nernst heat theorm

Third law of thermodynamics

Determination of absolute entropies of solids, liquids and gases

Applications of third law of thermodynamics (S0, G0 and equilibrium constant of chemical

reaction)

Tests of third law of thermodynamics, Residual entropy

Definition

Concept of chemical potential, Gibbs-Duhem equation

Variation of chemical potential with temperature and pressure

Determination of partial molar properties by method of intercept

Applications of chemical potential (Henrys law, Raults law and Nernsts distribution law)

3. Activity of Electrolytes

Ionic Activity:

Introduction

Derivation of a2 = a++ a- - and a2 = a+ a- for 1-1 electrolyte

Mean Activity a , its relation with a+ and a-

Relationship between a2 and a i.e. a2 = a

Mean ionic activity coefficient f and f+ , f-

Ionic Strength: Definition, Explanation and Equation

Debye Huckel Limiting Law (Without derivation):

Derivation of - log f = Az+z- 1/2

Interpretation of Equation

Graph of - log f 1/2 and its explanation / discussion

Empirical correction of Debye Huckel Limiting Law for

(1) Size of ion and

(2) Orientation of solvent molecules

BSc Syllabus 2017-18 Semester V&VI Chemistry

Solubility method

emf methods: (1) Chemical cell with transference

(2) Concentration cell without transference

Examples based on theory.

4. Electrochemistry

Concentration cells: Definition, (1) Electrode concentration cells (2) Electrolyte concentration cells,

Concentration cells without transference,

Concentration cells with transference,

Liquid junction potential, Elimination of liquid junction potential.

Applications of emf measurements: Determination of

(1) Solubility of sparingly soluble salts,

(2) Valency of metal ion,

(3) Dissociation constant of weak acid,

(4) Transport number of ion,

(5) Ionic product of water,

(6) Degree of hydrolysis

(7) pH by different electrodes

Example

Reference Books (Physical Chemistry)

(1) Elements of Physical Chemistry, S Glasstone and D Lewis, Macmillon and Co Ltd., New Delhi

(2) Principles of Physical Chemistry , S H Maron and C F Prutton, Oxford and IBH, New Delhi

(3) Thermodynamics for Chemists, S Glasstone, Affiliated East West Press Pvt Ltd, New Delhi

(4) Elements of Physical Chemistry, B R Puri, L R Sharma, M S Pathania Vishal publishing Co Jalandhar.

(5) Advanced Physical Chemistry, J. N. Gurtu, Pragati Prakashan, Meerut.

(6) Physical Chemistry, N. Kundu and S. K. Jain, S.Chandand Co. NewDelhi

(7) Physical Chemistry, K. L. Kapoor, Macmillan India Ltd. Delhi

(8) Physical Chemistry, B. K. Sharma Goel Publishing House, Meerut.

(9) Thermodynamics, Dr. Gurdeep Raj, Goel Publishing House Meerut

(10) Introduction to Electrochemistry, S. Glasstone , Affiliated East West Press Pvt Ltd, New Delhi

Unit-II : Analytical Chemistry [40 Marks].

Electrochemistry ( conductometry )

Electric transport , conductance in metals and in electrolyte solution

Specific conductance, equivalent conductance

Importance of conductivity electrodes. and platinization of electrodes

Variation of specific conductance with dilution as well as area of cross section of dip type

electrode and distance between two plates of electrodes etc.

Kohl raurch law and its importance, cell constant and its importance.

Conductometric Titration :

(1) Strong acid - strong base

(2) Strong acid - Weak base

(3) Weak acid Strong base

(4) Weak acid Weak base

(5) Mixture of strong acid + Weak acid - strong base

Precipitation Titration :

(1) AgNO3 NaCl

(2) BaCl2 K2SO4

(3) Ba(OH)2 MgSO4

Replacement Titration :

(1) Salt of weak acid strong acid

(2) Salt of weak base strong base

Degree of hydrolysis and Hydrolysis constant

Determination of solubility and solubility product of sparingly soluble salt, for the measurement

of conductivity

Importance of conductivity water and temperature for the measurement of conductivity

BSc Syllabus 2017-18 Semester V&VI Chemistry

2. Chromatography

Introduction,

Classification of chromatography - types of chromatography

Detail study of

(1) Adsorption (Column) chromatography

(2) Partition chromatography paper and TLC.

(3) Gas chromatography- GLC & GSC

(4) Ion exchange chromatography.

Application such as main physical characteristic of chromatography: Solubility,

adsorption value, volatility , Rf value , Rx value , nature of adsorption etc.

(I) Column chromatography:

Principles,

Method of separation of green leat pigment , mixture of inorganic ,vitamins ,colors of

flowers etc. separation of , , carotene from carrot.

(II) Partition chromatography :

(1) Paper chromatography

(2) TLC

(1) Paper chromatography :

Principle of paper chromatography

Experimental methods like :

Ascending and Descending method containing one dimensional and two dimensional method;

circular method and its Rf value , Rx value ;circulation method, separation of amino acid, sugar, phenyl

amine glycine and Fe+2 , Co+2 , Ni+2 mixture using spray reagent ninhydrine and aniline phthalate

(b) TLC :

Introduction of principles ;

Method of preparation of chromatoplate, Experimental techniques, superiority of TCL. over

other chromatographic Techniques, Application of TLC.

(III) Gas chromatography

Introduction,

Principle of GLC and GSC

(1) GLC:

Instrumentation, evaluation selection and characteristic of carrier gas, Effect of temperature &

pressure of gas, application.

(2) GSC:

Methods and its application.

(IV) Ion Exchange chromatography :

Introduction

Principle

Type of resins

Properties of ion exchange resins

Basic requirement of useful resins

Method of separation with illustration curve

Application of ion exchange resins

3. Introduction of complexometry Titration

Method of preparation of standard E.D.T.A. Solution,

Velchers law explanation of pm EDTA vol.,Graph with stability constant value.

Types of EDTA Titration (I) Direct Titration (II) Back Titration (III) Substitution Titration (IV)

Alkalimetry titration mixture with the help of masking and demasking agent ;

Principle of metal ion indicator,Use of EBT, calcon , muroxide with structure and characteristic.

4. Potentimetric and pH metry :

Introduction and interpretation of pH metry and potantiomtry.

Importance of indicator and reference electrode in the measurement of EMF and pH

E.M.F. method :

(I) Study of acid base Titration

(II) Redox Titration

BSc Syllabus 2017-18 Semester V&VI Chemistry

(III) Argentometric Titration include mixture of Cl, Br , I with graph and proper explanation.

pH metry :

Definition,

Interpretation of various methods of determining pH value like pH paper method

(Demonstration only), potentiometric method using only hydrogen electrode as indicator

electrode and calomel electrode as reference electrode to determine pH value.

Weak acid strong base Titration with curve and determination of dissociation constant (Ka)

of weak acid.

Reference Books (Analytical Chemistry):

(1) Fundamental of analytical chemistry by skoog & west

(2) Instrumental method of chemical analysis By B. K. Sharma 22 wilhim

(3) Water analysis and water pollution by V. P. Kudesia

(4) Instrumental method of chemical analysis By Chatwal Amreli

(5) Thin layer chematography by Egal stall

(6) Book for water analysis: By R.K. Trivali, V. P. Kulesiya.

(7) Analytical Chemistry by click

(8) Inorganic inflictive analysis by Vogel and Gehani Parekh

(9) Electronic methods of analysis by brewing

(10)Principle of instrumental analysis by S korg.

[Minimum 12 inorganic mixtures should be analyzed]

To analyze the given inorganic mixture containing six radicals

[Minimum 8 synthesis should be done] [20 marks]

I. Acetylation / Benzoylation:

1. Acetylation of salicylic acid

2. Acelytation of aniline

3. Acelytation of phenol

4. Benzoylation of aniline

5. Benzoylation of phenol

II. Aliphatic Electrophilic substitution:

1. Preparation of iodoform from ethanol

2. Preparation of iodoform from acetone

III. Aromatic Electrophilic Substitution:

Nitration:

1. Preparation of m-dinitrobenzene,

2. Preparation of nitro acetanilide.

Halogenation:

1. Preparation of p-bromo acetanilide,

2. Preparation 2:4:6 -tribromo phenol

IV. Diazotization / Coupling:

1. Preparation of methyl orange

2. Preparation of methyl red

V. Oxidation: Preparation of benzoic acid from benzaldehyde

[Minimum 12 exercises should be done]

Potentiometry

1. To determine normality and dissociation constant of benzoic acid using 0.1N NaOH.

2. To determine normality of given acid xN HCl using NaOH solution.

3. To determine concentration of xN FAS using K2Cr2O7.

BSc Syllabus 2017-18 Semester V&VI Biotechnology

4. To determine normality of each halide in the mixture using 0.1N AgNO3 solution.

5. To determine normality and dissociation constant of benzoic acid using 0.1N NaOH.

Polarimeter

1. To determine specific rotation of three different concentration (10%, 5%, 2.5%) of dextrose solution.

From graph find out the unknown concentration by plotting concentration v/s rotation angle.

2. Study the inversion rate of sugar in presence of 1N HCl and determine the rate of reaction.

Surface tension:

1. Find the surface tension of the liquids A, B, and C by using Drop-weight method. Find the value of

Parachor of liquids and CH2 group.

Thermodynamics:

1. Calculate entropy of vapourization (Sv) of a given liquid by plotting a graph of log (1/time) vs

(1/temperature).

Chromatography:

2. To determine Rf value of individual and mixture of amino acid by ascending paper chromatography.

3. To determine Rf value of individual and mixture of amino acid by circular paper chromatography.

4. To determine Rf value of individual and mixture of amino acid by thin layer chromatography (TLC).

5. To determine Rf value of individual and mixture of metal ions by ascending paper chromatography.

6. To determine Rf value of individual and mixture of metal ions by circular paper chromatography.

[ Total Marks: 100 marks { 60 Project Report + 40 Presentation ]

Project Report must be submitted in 35 to 50 pages

Presentation using OHP or PowerPoint for 5 minutes

Biotechnology

SEMESTER V

BT 501 - Bioprocess and Biochemical Engineering

Theory

Unit - 1

1.1 General Consideration: Metabolic Pathways and Metabolic Control Mechanism, Primary and Secondary

Metabolites.

1.2 Enrichment Techniques for isolation and Screening of microorganism, Primary and Secondary screening

1.3 Strain Improvement : Nature of mutation, mutagenesis, isolation of mutants

1.4 Strain Improvement : Application of recombinant DNA technique in strain construction

1.5 Techniques for preservation and storage of cultures

Unit 2

2.1 Fermentor and bioreactor : Design and types of various fermentors

2.2 Introduction to Aeration and agitation, oxygen transfer rate, heat control

2.3 Basic concept of growth and growth kinetics

2.4 Batch, fed-batch and continuous culture operations, chemostat and turbidostat

2.5 Starter culture, its importance and preparation

Unit 3

3.1 Introduction and types of fermentation media

3.2 Raw materials used in fermentation media

3.3 Media optimization

3.4 Sterilization of media, air and equipments

3.5 Automation (process computerization)

Unit 4

4.1 Overview of downstream processing

4.2 Extraction and separation techniques;

Cell disruption disintegration

Flocculation & Floatation

Filtration

Centrifugation

BSc Syllabus 2017-18 Semester V&VI Biotechnology

Solvent-Solvent Extraction

Distillation

Membrane filtration and dialysis

Chromatographic methods

Crystallization and drying

4.4 Bioassay, Quality control procedure and

4.5 Fermentation Economics

Unit 5

5.1 Fermentation processes of alcohol, organic acids (Gluconic acid & Citric acid)

5.2 Fermentation processes of amino acids (Lysine), vitamins (Vit. B12), antibiotics (penicillin)

5.3 An overview of solid state fermentation

5.4 Immobilization Techniques: Immobilization of cell and enzyme: Basic concept of immobilization, principles,

mechanism and techniques of immobilization. Choice of immobilization methods, properties of immobilized

enzyme stability and kinetic properties.

5.5 Supporting matrices used and their properties. Examples of the techniques in biotechnology: Alcohol, semi

synthetic antibiotics and amino acids production

Practicals

Ex: -1 Isolation, Screening and characterization of Lipolytic, Proteolytic, Amylolytic microbes and enzymes

Ex: -2 Screening of antibiotic producing microorganisms (Crowded & Wilkins Method).

Ex: -3 Determination of growth phases of microorganisms

Ex: -4 Optimization of medium parameters (pH, Temperature, Salt, Carbon & Nitrogen) for the production of biomass

and enzymes (Invertase)

Ex: -5 To demonstrate various techniques of bioassay for antibiotic

Ex: -6 Typical fermentation of alcohol & Gluconic Acid.

Exp 7 Gel entrapment of yeast cells and to determine invertase activity by the immobilized cells

References

1. Mukhopadhyay. Process Biotechnology Fundamental. Viva Book

2. Shuler and Kargi, 1992. Bioprocess engineering. Prentice-Hall.

3. Bialy & Ollis. 1986. Biochemical Eng. Fundaments. McGraw-Hill.

4. Schugerl. 1987. Bioreaction engineering. J/W.

5. Stanbury and Whitaker. Principles of fermentation technology.

6. Sikyta. Methods in Industrial microbiology. Ellis Hardwood Ltd.

7. Krijsman. Product recovery in bioprocess technology.

8. T.K.Ghose. Bioprocess computation in biotechnology. Ellis Hardwood Ltd.

9. Murray Joh. 1997. Microorganisms and Biotechnology.

10. Demain (ED). 1999. Manual of mdustrial Microbiology and Biotechnology. Asm Press.

11. Bioprocess Engineering Principles by Doran (D); Academic Press, 1998

12. Cooney, A.E. Humphrey, Comprehensive Biotechnology: The principles and Regulation of

Biotechnology in Industry, Agriculture and Medicine, Vol.2, Pergamon Press, 1985

13. Doran. Bioprocess Engineering Principles - Academic Press - 2001

14. Michael L. Shuler and Fikret Kargi (2003). Bioprocess engineering basic concepts. (2nd edition). Prentice

Hall of India Pvt. Ltd. India.

15. Bioprocess technology: Fundamentals and applications, KTH Stockholm.

BT 502 - Genetics & Molecular Biology

Theory

Unit - 1 Classical Genetics

1.1 Gene structure & organization: Fine Structure of gene (Cistron, Recon, Muton) Structure of eukaryotic gene.

Organization of genes (Gene family) Pseudo genes, Allele, Multiple allele, Pseudo allele, Lethal genes,

Pleiotropic gene.

1.2 Mendelian inheritance: Inheritance patterns & Laws of Heredity.

1.3 Gene Interaction: Allelic Interaction (Dominance, Incomplete Dominance & Co-Dominance) Non allelic

Interaction (Supplementary, Complementary & Duplicative genes, Epistasis).

1.4 Linkage & Linkage Maps

1.5 Chromosomal Aberrations, Sex Determination

BSc Syllabus 2017-18 Semester V&VI Biotechnology

2.1 Genetic polymorphism, Genetic Drift & Hardy Weinberg Law of equilibrium.

2.2 Extra chromosomal Inheritance,

2.3 DNA as genetic material : Experimental evidences (Direct & Indirect Evidences)

2.4 Watson & Crick Model, Alternative forms of DNA, C-value paradox.

2.5 Genomic organization of prokaryotic & eukaryotic cells, Concepts of Central Dogma.

Unit - 3

3.1 Replication Experimental evidences of DNA replication & Enzymes involved in DNA replication

3.2 Process of replication in Prokaryotes & Eukaryotes (Overview of eukaryotic DNA replication with SV 40 as

an example)

3.3 DNA repair Mechanism: Preventative, Direct & Post Replication repair

3.4 Process of gene recombination: Mechanism of gene transfers transformation, conjugation and transduction.

3.5 Transposable elements: Structure & Mechanism of Transposition, Transposable elements in eukaryotes (Ac-

Ds Elements, P-elements, Retro-Transposons & retroposons)

Unit - 4

4.1 Transcription: Overview of Transcription & Types of RNA Molecules.

4.2 Process of Transcription, RNA Processing & Post Transcriptional Modifications.

4.3 Machinery of Protein Synthesis: Genetic code, Ribosomes & Role of t-RNA.

4.4 Process of Translation & Brief discussion of Post translational modifications

4.5 Regulation of gene expression Lac-operon & Trp operon

Unit 5 Concept of Gene Cloning

5.1 Steps of Genetic Engineering & Enzymes involved.

5.2 Cloning Vectors: Plasmids, Phages, Cosmids, YACs, BACs, Expression Vectors (Overview)

5.3 Cloning strategies: Shot gun method, Homopolymer tailing, Linkers and Adaptors.

5.4 Screening of Recombinants (Blue white screening, Nucleic Acid Hybridization Method)

5.5 Applications of Genetic Engineering

Practicals

Ex: -1 Preparation of genomic DNA from bacteria

Ex: -2 Isolation of genomic DNA from Blood

Ex: -3 Quantitation of DNA by spectrophotometry

Ex: -4 Isolation of plasmid DNA from bacteria

Ex: -5 Agarose gel electrophoresis of isolated DNA

Ex: -6 Bacterial transformation:

6.1 Preparation of competent cells

6.2 Transformation

Ex: -7 Restriction enzyme digestions and its analysis by gel electrophoresis

Ex: -8 U.V. Induced Mutagenesis.

Ex: -9 Problem solving on Mendelian Principles

Ex: -10 Problem solving on Hardy Weinberg Law of equilibrium

References

1. Genetics and Molecular Biology

2. Garder, Principles of genetics, Wiley Publications, 8th edition

3. Levin, Gene VI to Gene VIII, Oxford Pub.

4. Friefelder, Essentials of Molecular Biology, Panima Pub

5. T. A. Brown ,Genome-2 2nd Edition

6. Old & primrose, Principle of Gene Manipulation, Blackwell Pub.

7. Weaver Molecular Biology, Mc Graw Hill

8. Brown, Gene Cloning and DNA analysis, Blackwell Pub.

9. Winnacker, From genes to clones , Panima Pub.

10. P.C. Tumer, Instant notes in Immunology, Viva books Pub.

11. Griffith, Introduction to genetic analysis, Freeman publication, 8th edition

12. Robert Broker, Genetics, Mc Graw Hill

13. Strickberger, Genetics, Prentice Hall Pub.

14. T. A. Brown, Gene Cloning DNA analysis-Blackwell Pub.

15. Stephen Hunt, Functional Genomics Oxford, Tokyo

BSc Syllabus 2017-18 Semester V&VI Biotechnology

17. Verma,Cell biology ,Genetics ,Molecular Biology, Evolution & Ecology.2006

18. Karp,Cell & Molecular Biology: concepts & Experiments.4th Edition.

19. Lodish,Cell & Molecular Biology,W.H.Freeman.5th Edn.

20. Watson, Molecular Biology of the Genes. Pearson Publication.

21. Wilson, & Walker. 1995. Principles and techniques of practical Biochemistry.

22. Becker. 1996. Biotechnology: A laboratory course

23. Lenhinger. Principles of biochemistry,2nd Edn.

24. Glick, Molecular Biotechnology,ASM Publication.

25. Becker & Hardin, The world of the Cell, Pearson Pub.

26. C.B.Powar, Cell Biology, Himalaya Press.

27. Nelson & Cox, Lehninger Principle Biochemistry, Freeman Pub.

28. Desiker, Cell & Development Biology, Dominant Pub.

29. Albert, Essential Cell Biology,Garland Science.

30. Geoffrey Cooper ,The- Cell Molecular Approach, ASM Pub.

31. Ben Hui Liu, Statistical Genomics : Linkage, mapping & QTL Analysis, CRC press

32. Nicholl, An Introduction to Genetic Engg. - 2 ed, Cambridge

33. Primrose, Principles of Gene Manipulation - 6 ed, Blackwell

34. Winnacker, From Genes to Clones, Panima

35. Primrose, Principle of Gene Manipulation, Blackwell

36. Griffiths, Intro. to Genetic Analysis - 8ed, Freeman Pub.

37. Maxine singer-berg, Genes - Genomes, Uni. Sci. Book

38. T.A.Brown, Gene Clonning - DNA Analysis, Blackwell

39. John Witkowski, Recombinant DNA, Scientific American

40. Piramal, Molecular Biotechnology, Dominant Pub.

41. Maxine singer & Paul Berg, Exploring Genetic Mechanism, Uni.science Books

42. Bruce Patterson, Techniques in Quantification & Localization of Gene Expression, Birkhaus Pub.

43. Reed , Holmes, Jonathan Weyers, Practical Skills in Bimolecular Sciences

44. Anthony, Griffiths, William M, Modern Genetic Analysis :Integrating Genes and Genomes

BT 503 - IMMUNOLOGY

Theory

Unit - 1

1.1 Historical Perspective, Innate Immune response and its role in protection

1.2 Adaptive Immune response - Humoral and cellular component of the Immune response, Comparison

between Innate and adaptive immunity.

1.3 Hematopoiesis

1.4 Cells of the Immune System.

1.5 Organs of the Immune System : Primary and Secondary Lymphoid Organs

Unit - 2

2.1 Antigen: Characteristics of antigens, Factors that influence immunogenicity, Cross reactivity, Epitopes,

Haptens, Adjuvants.

2.2 Immunoglobulins: Structure, Classification & Functions.

2.3 Genetic events in synthesis of Ig Chains: Organization & Synthesis of Light chain genes & Heavy chain

genes, Class & Isotype Switching

2.4 Monoclonal Antibodies: Production by Hybridoma Technology & Applications

2.5 Antigen and Antibody Interactions-(Agglutination, Precipitation, ELISA, RIA, Immunoflorescence &

Western Blotting)

Unit - 3

3.1 MHC: MHC molecules and organization of their genes, Structure and function of MHC gene products

3.2 Antigen Processing and Presentation

3.3 T- Cell Receptor

3.4 T- Cell Maturation, Activation, Differentiation

3.5 B- Cell Maturation, Activation, Differentiation

Unit - 4

BSc Syllabus 2017-18 Semester V&VI Biotechnology

4.2 Complement System: Function, Component, Activation and Regulation

4.3 Cell Mediated Effector Responses

4.4 Inflammation

4.5 Vaccines

Unit - 5

5.1 Immune response to Infectious Diseases : Viral (Influenza), Bacterial (Tuberculosis), Protozoan (Malaria)

5.2 Immunodeficiency Diseases Primary (SCID) & Secondary (AIDS)

5.3 Autoimmune Diseases: Organ Specific (Graves disease, Insulin dependent diabetes mellitus) and Systemic

Autoimmune Diseases (Rheumatoid Arthritis, Multiple sclerosis).

5.4 Transplantation Immunology: Graft rejection, Evidence & Mechanism of Graft rejection, Prevention of

Graft rejection, Immunosuppressive Drugs

5.5 Hypersensitive Reactions

Practicals

Ex:-1. Total & Differential Count of blood cells

Ex:-2. Agglutination & Precipitation:

Blood Grouping

Widal Test (Slide /Tube)

Oucterlouny Double diffusion (ODD)

HIV detection rapid test

SRID (Single Radial Immunodiffusion)Test

Latex Agglutination

Ex:-3. Dot ELISA, ELISA Test

Ex:-4. Rocket Immunoelectrophoresis (Demonstration)

Ex:-5. Gel Techniques; SDS PAGE/Western blot

Ex:-6. Antigen-Antibody reactions Coombs test.

Ex:-7. Purification of Immunoglobulin (Demonstration)

References

1. Janis Kuby, Immunology, 5th Edition

2. Ivan Roitt, Essential Immunology, 9th Edn.

3. Ananthnarayan, Medical microbiology

4. Mary S. Leffell,& Noel R. Rose, Handbook of Human Immunology, CR

5. Tizzard, Immunology

6. Elgert Immunology

7. Lidyard, Instant notes in Immunology, 2nd Edition.

8. Darla J wise, Immunology-A comprehensive review : A Blackwell science Pub.

9. Todd & Spickett, Immunology

10. Delves & Roitte Encyclopedia of Immunology- Vol-1 to Vol.-4, 2nd Edition

11. A handbook of practical and clinical immunology. Talwar GP and Gupta SK (1992) CBS Publications

12. Using Antibodies: A Laboratory Manual. Harlow & Lane (1998) Cold Spring Harbor Lab Press.

13. Immunological Techniques Made Easy. Cochet, et al. (1998) Wiley Publishers, Canada.

14. Clinical Immunology Principles and Laboratory Diagnosis. Sheehan (1990)

SEMESTER VI

BT 601 - Principles of Biotechnology Applied to Plants and Animals

Unit - 1 Plant Tissue Culture - I

1.1 Introduction & History of plant tissue culture

1.2 Laboratory requirements

1.3 Aseptic techniques

1.4 Culture medium: Nutritional requirements of explants, PGRs & their in vitro roles, media preparation.

1.5 Explant: Characteristics, Sterilization & Selection

Unit - 2 Plant Tissue Culture - II

2.1 Principles of tissue culture: Totipotency, Cyto-differentiation.

BSc Syllabus 2017-18 Semester V&VI Biotechnology

2.3 Haploids: Anther & pollen culture

2.4 Somatic embryogenesis & synthetic seed production

2.5 Protoplast Culture: Principle, Methods of fusion, somatic hybridization, Identification of hybrids.

Unit - 3 Plant Tissue Culture - III

3.1 Genetic transformation in plants: Vector mediated & Non vector mediated methods.

3.2 Application of tissue culture in agriculture, forestry & flory culture.

3.3 Secondary metabolite production from plants using in vitro tools.

3.4 Bioreactors for cell culture techniques.

3.5 Transgenic plants applications - Plantibodies, Edible Vaccines & BT Cotton

Unit - 4 Animal Tissue Culture - I

4.1 Animal tissue culture: History, Scope & importance

4.2 Laboratory requirements & aseptic techniques

4.3 Culture medium: Requirements, Types: Natural, chemically defined & synthetic media

4.4 General procedure for tissue culture: Disaggregation (Enzymatic & Non enzymatic)

4.5 Maintenance, Quantitation.

Unit - 5 Animal Tissue Culture - II

5.1 Primary culture, Secondary culture (Transformed cell & continuous cell lines)

5.2 Cloning & Selection of Cell lines

5.3 In Vitro Fertilization: Need & general Methodology

5.4 Transformation method in animals: Biological, Physical & Chemical.

5.5 Application of transgenic animals

Practicals

1. Plant tissue culture: laboratory organization facilities & equipments

2. Aseptic techniques: Washing, Packing & Sterilization

3. Preparations of stock solutions

4. Preparation of Plant tissue culture media: MS, Nitsch & Whites medium.

5. Production of callus culture & study of characteristics

6. Preparation of synthetic seeds: Encapsulation Techniques

7. Isolation of Protoplast

8. Isolation of DNA from plants

9. Preparation of media for animal cells & tissues (Theory)

References

1. Introduction to Plant Tissue Culture: M.K. Razdan

2. Plant Tissue Culture Theory & Practical: S.S. Bhojwani & M.R. Razdan

3. Plant Tissue Culture: Kalyankumar Dey.

4. Slan A.C. (1996) Plant Tissue Culture- Oxford & BH Publishing co. Pvt. Ltd.

5. Lydiane kyle John Kleyin plant test tubes: An Introduction to micro propagation.

6. Introduction to plant biotechnology by H.S. Chawla

7. Animal Tissue Culture - Mathur

8. Animal Tissue Culture - Freshney

9. Animal biotechnology - Ranga

10. Cell & Tissue Culture in animals Masters

Theory

Unit - 1

1.1 Basics of Biochemical and Molecular biology studies

1.2 Quantitative biochemical measurements, Unit of measurements and safety in the laboratory

1.3 Radioisotope Techniques: The nature of radioactivity -atomic structure, atomic stability and radiation, types

of radioactive decay, units of radioactivity.

1.4 Detection and measurement of radioactivity. Geiger Muller Counters, Scintillation Counting.

autoradiography. safety guidelines

1.5 Applications of Radioactivity and health hazards associated with radioactivity

Unit - 2

BSc Syllabus 2017-18 Semester V&VI Biotechnology

2.2 Agarose electrophoresis, PAGE, SDS PAGE, 2D PAGE

2.3 Isoelectrofocussing, Capillary Electrophoresis

2.4 Centrifugation: Introduction, Basic Principle of Sedimentation, The basic components of

centrifuge{Electric rotar, Drive Shaft, Rotars to hold Tubes etc}

2.5 Preparative and analytical Centrifuges;Density gradient Centrifugation {Zonal and Isopycnic}, Differential

Centrifugation

Unit - 3

3.1 Spectroscopy: Properties of electromagnetic radiation, Interaction of EM radiation with matter. Physical

Phenomenon-Absorption, Emission, Refraction, Diffraction, Transmission.

3.2 Beer Lamberts Law, Extinction Coefficient, Principle and Application: UV-Visible light Spectroscopy.

3.3 Atomic Absorption & Emission Spectroscopy

3.4 Mass Spectroscopy, X ray Diffraction and Crystallization-Basic principle & biological applications.

3.5 Brief Overview of IR & NMR Principle & biological applications.

Unit - 4

4.1 Chromatography: Chromatography theory and principles

4.2 Partition theory: Retention and differential migration mechanism (impelling retarding forces) and

equilibrium between two phases, definition of key terms: retention time, peak shape, band broadenings,

column efficiency, Rate Theory (HETP), resolution, selectivity, normal chromatography & Reverse.

4.3 Properties of solvents (MP), stationary phase and supporting phase.

4.4 Classifications of the technique, Types: Paper Chromatography, TLC, Column Chromatography, Partition,

Adsorption, Ion exchange, size exclusion, Affinity chromatography.:

4.5 GC/GLC, FPLC and HPLC

Unit - 5

5.1 Biosensors:- Introduction, Principle, Characteristics of Ideal Biosensor, Application of Biosensor

5.2 Different types of biosensors

5.3 Nanotechnology: Fundamental Concept, Techniques & Applications.

5.4 Electroanalytical techniques, potentiometer, coulometry, voltametry

5.5 Patenting and IPR

Practicals

1. Laboratory safety rules

2. Computation of percent solution. Molarity, ppm, ppb and stock solution

3. Complementary color

4. Determining max of given solution using spectroscopy

Quantification of Protein using

5. Folin-Lowry assay

6. Bradfords method

7. Spectrometric assay

8. Centrifugation

(A) Principles and Instrumentation

(B) Problem solving g and RPM of centrifuge

Chromatography

9. Solvent-Solvent extraction

10. Separation of amino acids by Thin Layer chromatography

11. Separation of plant pigments by Paper Chromatography

12. Demonstration of gel filtration chromatography

13. Polyacrylamide gel electrophoresis

14. Ammonium Sulphate precipitation.

15. Desalting of protein by dialysis

References

1. Harmes. Biochemistry.2nd Ed. Viva Book.

2. Fisher. Chemistry for biologists. Viva Books.

3. Wilson, & Walker. 1995. Principles and techniques of practical Biochemistry. Cambridge Univ. Press.

4. Davidson V.L. & Sittman. 1993. Biochemistry.

5. Blood & other 1996. Laboratory DNA Science. Benjamin.

6. Boyer. 2001. Modern Experimental bioch. 3/e. Addison

BSc Syllabus 2017-18 Semester V&VI Biotechnology

8. Plumner. An introduction to practical Biochemistry.

9. J.Jayraman. Lab Manual in Biochemistry.

10. Chirikjian, J.P. 1995. Biotechnology Theory and Technique for undergraduate laboratories Vol.1. Jones

and Barlett Pub.

11. Tinoco . Iand others. 1995. Physical chemistry Principles and applications in biological Sciemnces.

Prentice-Hall.

12. Paul H. Teesdale & others. 2001. Essentials of Biological chemistry. J/W.

13. Switzer and Gauity. 1995. Experimental Biochemistry WH Freeman.

14. Voet Donald. 1999. Fundamentals of Biochemistry, J/W.

15. Athel Cornish-Bowder. 1999. Basic mathematics for biochemists. OUP.

16. Elliott & Elliott. 2001. Biochemistry and molecular bilogy. OUP.

17. Millar Thomas. (ED). 2000. Biochemistry explained: A practical guide to learning Biochemistry.

Hardwood Aca. Publ.

18. Haynie, D.T. 2001. Biological thermodynamics Cambridge Univ. Press.

19. Hargreaves and Thmpson (Ed). 1999. Biochemistry of Exercises X. Human Kinetics Publ.

20. Aldridge, Susan. 1994. Biochemistry: a textbook for A - level biology: Practical Guide. Cambridge Univ.

Press.

21. Seidman and Moore. 2000. Basic laboratory methods for biotechnology. Longman

BT 603 - Advanced Molecular Techniques & Bioinformatics

Theory

Unit - 1

1.1 DNA Amplification : PCR -Types and Applications

1.2 DNA Sequencing: Maxam Gillbert, Sangers Dideoxy, Automated, Pyrosequencing, PCR Based Methods

1.3 Artificial synthesis of DNA (Gene Machine/ DNA Synthesizer)

1.4 Autoradiography

1.5 Hybridization Techniques: Southern, Northern & Western Blotting

Unit - 2

2.1 Basic concepts of Molecular Markers: RFLP, RAPD, Micro satellite & Mini satellite

2.2 Primer Designing

2.3 Restriction Mapping

2.4 DNA Foot Printing

2.5 Chromosome Walking & Chromosome Jumping

Unit - 3

3.1 History & Future prospects of Human Genome Project

3.2 Microarray-Principle & Applications

3.3 Overview of Bioinformatics & Applications

3.4 Introduction, Need & Types of databases.

3.5 Biological Databases: Nature of Biological data, Importance of Biological Databases in Biological

Discovery

Unit - 4

4.1 Introduction to bibliographic databases: PubMed

4.2 Major Bioinformatics Resources: NCBI, EBI & ExPASY

4.3 Nucleic acid sequence databases: GenBank, EMBL, DDBJ

4.4 Protein sequence databases: Uniprot

4.5 Homology and similarity search tools: BLAST, FASTA

Unit - 5

5.1 Protein Structure data base: PDB

5.2 Structural Classification of Proteins

5.3 Multiple Sequence Alignment

5.4 Overview of Comparative & Functional Genomics

5.5 Phylogenetic Analysis

Practicals

1. Introduction to literature database at NCBI and querying the PUBMED database using the ENTREZ search

engine.

2. Getting the gene sequences by exploring and querying the nucleic acid databases. GenBank, EMBL & DDBJ

BSc Syllabus 2017-18 Semester V&VI Biotechnology

4. Multiple alignment of the given sequences by using ClustalW

5. Overview of OMIM & data retrieval

6. Getting the amino acid sequences by exploring and querying the protein sequence database. Swiss Prot,

Uniprot

7. 3-D Protein structure visualization and measurement of bond length, bond angle and torsion angles using

RasMol.

References

1. Introduction to Bioinformatics by T. Attwood and D. Parry-Smity, Prentice Hall

2. Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins by A.D. Baxevanis and B.F.F

Ouellette, Wiley Interscience.

3. Essentials of Genomics and Bioinformatics by C.W. Sensen, John Wiley and Sons

4. Bioinformatics: Sequence and Genome Analysis by D.W. Mount, Cold Spring Harbor Laboratory Press.

5. Lesk, A.M. 2002, Introduction to Bioinformatics. Oxford University Press

6. Rastogi, S.C., Mendiratta, N. and Rastogi, P. 2004 Bioinformatics: Concepts, Skills & Applications. CBS

Publishers & Distributors

7. Andreas D. Baxevanis, Current Protocals in Bioinformatics, John Wiley & Sons

BSc Syllabus 2017-18 Semester V&VI Microbiology

Microbiology

SEMESTER - V

MB-501: Applied Microbiology

Unit - I: Microbiology of Soil

A. Properties of soil

1.1 Physical & Chemical Characteristics of Soil

1.2 Rhizosphere & Microbial flora of Soil

1.3 Interactions among soil microorganisms: Neutral, Beneficial & Harmful interactions

B. Biogeochemical cycles

1.4 Introduction of Mineralization & immobilization of elements

1.5 Nitrogen Cycle: Proteolysis, Ammonification, Nitrification, Nitrate reduction, Denitrificaiton;

Biochemistry & genetics of nitrogen fixation (nif gene technology)

1.6 Sulfur Cycle: Sulfur oxidation & Reduction, Winogradskys Column

1.7 Carbon cycle: Degradation of complex organic compounds, formation of humus and its important

Reference Books

1. Principles of Microbiology By Atlas R.M.: 2nd edition

2. Microbiology by Pelczar M.J. & Chain E.C.S. : 5th edition

3. Introduction to soil microbiology by Alexander M: 2nd edition

4. Biotechnology fundamental & applications By Purohit S.S.

5. Diseases of Crop plants in India by Rangaswami G.

6. Microbiology fundamental & applications By Purohit S.S.

7. Microbiology by Prescott L.M.

Unit II: Food Microbiology

2.1 Microbial flora of fresh food

2.2 Microbial spoilage of foods: Fresh foods & Canned foods

2.3 Food Borne infection & intoxication: Role of S.aureus,, C.botulinum & Salmonella Spp.in food

poisoning

2.4 Preservation of foods: General principles & methods of food preservation

2.5 Microbiological examination of food; Introduction to AGMark

2.6 Brief introduction about fermented foods: Pickles, Sauerkraut, Silage, Sausages & Bread

2.7 Microorganisms as food: Single Cell Protein, Mushrooms and Functional foods

Reference Books

1. Fundamentals of Microbiology By Frobisher M.: 9th edition

2. Microbiology by Pelczar M.J. & Chain E.C.S. : 5th edition

3. Industrial Microbiology by Prescott S.C. : 3rd edition

4. Food Microbiology by Frazier W.C. : 3rd edition

5. Food science & Experimental foods By Swaminathan M.

6. Modern food microbiology by J James

Unit III: Dairy Microbiology

3.1 Milk as a medium, normal flora of milk

3.2 Types of microorganisms in milk: Biochemical types, Pathogenic types, Temperature types

3.3 Spoilage of milk & milk products

3.4 Microbial analysis of milk: SPC, Direct count, MBRT, Resazurin test

3.5 Grading of milk

3.6 Fermented milk Beverages & Manufactured Dairy Products: Starter Culture, Cheese, Yogurt,

Buttermilk, Acidophilus milk, Kefir

3.7 Preservation of milk: Principles & methods of preservation

Reference Books

1 Fundamentals of Microbiology By Frobisher M.: 9th edition

2 Microbiology by Pelczar M.J. & Chain E.C.S. : 5th edition

3 Industrial Microbiology by Prescott S.C. : 3rd edition

4 Food Microbiology by Frazier W.C. : 3rd edition

5 Fundamentals of Dairy Microbiology by Prajapati J.B.

Unit IV: Aquatic Microbiology & Microbiology of Waste Water

A. Introduction

BSc Syllabus 2017-18 Semester V&VI Microbiology

4.2 Aquatic environment: Temperature, Hydrostatic pressure, Light, Salinity, Turbidity, pH, inorganic &

organic constituents

4.3 Distribution of microorganisms in the aquatic environment

B. Microbiology of drinking water

4.4 Sanitary survey, Bacteriological evidence of pollution, Bacteriological analysis & Sampling techniques

of water

4.5 Microorganisms other than Coliforms as nuisance organisms

C. Water purification

4.6 Sedimentation, Filtration use of Sand filters, Disinfection

D. Waste water

4.7 Chemical and Microbial Characteristics of waste water, B.O.D., C.O.D. as indicator of quality of waste

ater

4.8 Waste water treatment & Disposal - Single Dwelling Process & Municipal Treatment - Primary

Treatment, Secondary Treatment, Advanced & final treatment

4.9 Solid waste processing: Anaerobic Sludge digestion & Composting

Reference Books

1 Principles of Microbiology By Atlas R.M.: 2nd edition

2 Microbiology by Pelczar M.J. & Chain E.C.S. : 5th edition

3 Environmental microbiology by Rania Maier, Academic Press

4 Advanced Waste water Treatment by R.K. Goel

5 Microbiology fundamental & applications By Purohit S.S.

6 Microbiology by Prescott L.M.

Unit V: Environment and Biotechnology

A. Environment

5.1 Types of Pollutants, Sources & Effect on ecology

5.2 Pollution by pesticides, Biomagnifications of pesticide & their Biological control

5.3 Brief account on Water pollution (by Oil, Detergent, Heavy metal & industrial effluent) & their

Biological control

5.4 Role of microorganisms in Biodeterioration of Paper, Textiles, paints, woods & metals and their

control

5.5 Air Pollution & Air Sanitation

B. Biotechnology

5.6 What is Biotechnology, Biotechnology as interdisciplinary science

5.7 Ethical, Legal and Social Implications of Biotechnology

5.8 Bioleaching, Microbial enhanced oil recovery

5.9 Biofuels

5.10 Bioplastics

Reference Books

1 Principles of Microbiology By Atlas R.M.: 2nd edition

2 Biotechnology by Trevan M.D.

3 Environmental microbiology by Rania Maier, Academic Press

4 Biotechnology by Smith, Oxford

5 Biotechnology fundamental & applications By Purohit S.S.

6 Microbiology by Prescott L.M.

Practical

1 Isolation of nitrogen fixing bacteria

2 Cultivation of nitrifying and denitrifying bacteria (Demo)

3 Cultivation of cellulose decomposing microorganisms from soil(Demo)

4 Demonstration of oozing, and isolation of pathogen from diseased specimen of lemon leaf showing

citrus canker and isolation of Xanthomonas spp.

5 Standard qualitative analysis of milk

6 Methylene Blue Reduction Time test for milk

7 Estimation of DO.

8 Isolation and identification of coli forms from Water by Presumptive, Confirmed & Completed test

Reference Books

BSc Syllabus 2017-18 Semester V&VI Microbiology

1 International student edition: Microbiology- A laboratory Manual 4th edition. By James G. Chappuccino &

Natalie Sherman

2 Bacteriological Techniques By F.J. Baker

3 Introduction to Microbial Techniques By Gunasekaran.

4 Introductory Practical Biochemistry by S.K. Sowhney & Rundhir Singh

5 Standard Methods for Examination of waste water L.S. Clesceri, A.E. Greenberg & A.D. Eaton APHA

1998

MB-502- Bioprocess Technology

Theory

Unit I: Fermentation Technology & Industrially Important Microorganisms

A. Historical perspective and concept

1.1 General Concept and historical development of industrial microbiology

1.2 Range of Fermentation Processes

1.3 Component parts fermentation process

1.4 Economic aspects of fermentation industry

B. Isolation & improvement of industrially important microorganisms

1.5 Primary & Secondary Screening

1.6 Isolation methods using selection of desired characters

1.7 Improvement of industrially important microbes: Application of protoplast fusion and recombinant

DNA technology

1.8 Concept and application of bioinformatics in fermentation industry

Reference Books

1 Principles of Fermentation Technology By Stanbury & Whittaker : 2nd edition

2 Industrial Microbiology By Casida L. E.

3 A text book of industrial microbiology, 2nd edition By Wulf Crueger & Anneliese Crueger

4 Industrial Microbiology By A.H. Patel

5 Biotechnology: Food Fermentation Microbiology, Biochemistry & Technology Vol. 1 & 2 By V.K. Joshi &

Ashok Pandey

Unit II: Formulation of Fermentation media

2.1 Introduction, Types of Media and Medium formulation

2.2 Raw materials: Crude Carbon and Nitrogen sources

2.3 Minerals, Precursors, Growth Regulators, Buffers, Antifoam agents

2.4 Inoculum Medium

2.5 Media Optimization

Reference Books

1 Principles of Fermentation Technology By Stanbury & Whittaker : 2nd edition

2 Industrial Microbiology By Casida L. E.

3 A text book of industrial microbiology, 2nd edition By Wulf Crueger & Anneliese Crueger

4 Industrial Microbiology By A.H. Patel

5 Introduction to Bioinformatics by Institute of Bioinformatics, India

Unit III: Design and Aseptic Operation

3.1 Introduction and basic functions of fermentor

3.2 Types of bioreactors

3.3 Aeration and Agitation

3.4 Fermentation process: Batch Fermentation, Continuous fermentation and their comparative advantages

and disadvantages

3.5 Sterilization process in fermentation industries:

a. Fermentor sterilization

b. Medium sterilization

c. Sterilization of air and feed

3.6 Aseptic operation and Containment

Reference Books

1 Principles of Fermentation Technology By Stanbury & Whittaker : 2nd edition

2 A text book of industrial microbiology, 2nd edition By Wulf Crueger & Anneliese Crueger

3 Industrial Microbiology By A.H. Patel

Unit IV: Downstream Processes

BSc Syllabus 2017-18 Semester V&VI Microbiology

4.1 Methods of Cell separation: Broth conditioning, Precipitation, Sedimentation, Centrifugation, Filtration

4.2 Techniques of Cell Disruption: Mechanical and Non mechanical methods

4.3 Product Recovery: Liquid liquid extraction, Solvent recovery, Two Phase aqueous extraction, Super

critical fluid extraction

4.4 Physical, Chemical and Biological assay of fermentation products

Reference Books

1 Principles of Fermentation Technology By Stanbury & Whittaker : 2nd edition

2 Industrial Microbiology By Casida L. E.

3 A text book of industrial microbiology, 2nd edition By Wulf Crueger & Anneliese Crueger

4 Industrial Microbiology By A.H. Patel

Unit V: Studies of Selective Fermentation Processes

5.1 Production of organic solvents: Ethyl alcohol

5.2 Production of enzymes: Amylases and Proteases

5.3 Production of antibiotics: Penicillin and Streptomycin

5.4 Production of amino acids: Lysine

5.5 Production of organic acids: Citric acid

5.6 Production of vitamins: Riboflavin

5.7 Overview of Immobilization in fermentation process

Reference Books

1 Industrial Microbiology By Casida L. E.

2 A text book of industrial microbiology, 2nd edition By Wulf Crueger & Anneliese Crueger

3 Industrial Microbiology By A.H. Patel

4 Biotechnology: Food Fermentation Microbiology, Biochemistry & Technology Vol. 1 & 2 By V.K. Joshi &

Ashok Pandey

5 Biotechnology By M.D.Trevan

MB-502: Bioprocess Technology

Practical

1 Primary screening of industrially important microorganisms capable of producing: Antibiotics, Organic

acids, amylases

2 Bioassay of penicillin using B. subtilis

3 Laboratory fermentation & estimation of Ethyl Alcohol by Saccharomyces.

4 Laboratory fermentation & estimation of amylase by B. subtilis.

5 Sterility testing of fermentation products (Demo)

6 Immobilization of yeast cells by Ca- alginate entrapment method & Determination of viability of

immobilized cells by invertase activity. (Demo)

Reference Books

1 International student edition: Microbiology- A laboratory Manual 4th edition. By James G. Chappuccino &

Natalie Sherman

2 Bacteriological Techniques By F.J. Baker

3 Introduction to Microbial Techniques By Gunasekaran.

MB-503- Prokaryotic Metabolism

Theory

Unit I: Introduction to Metabolism, Bioenergetics and Enzyme Kinetics

1.1 Bioenergetics : The concept of free energy, Determination of G & Energy rich compounds

1.2 Energy metabolism: Role of ATP in metabolism, Role of reducing power in metabolism, Role of

precursor metabolites in metabolism

1.3 Non Regulatory Enzymes : Derivation of the Michaelis Menten Equation

1.4 Regulatory Enzymes : Conformational changes in Regulatory Enzymes

Reference Books

1 The physiology and Biochemistry of Prokaryotes, 2nd edition By David white

2 Outlines of biochemistry By- Conn E.E. and Stumpt P.K.: 4th Ed.

3 General microbiology by Stanier R.Y.: 5th Ed

4 Principles of Biochemistry By Lehninger

Unit II: Heterotrophic Mode of Metabolism

A. Catabolism of Carbohydrates :

2.1 Glycolysis and its regulation

BSc Syllabus 2017-18 Semester V&VI Microbiology

2.3 The Entner - Doudroff pathway

2.4 The Citric acid cycle and its regulation

2.5 The Glyoxylate cycle

B. Catabolism of protein and amino acids:

2.6 General reactions of amino acids catabolism, Stickland Reactions

C. Catabolism of lipids:

2.7 Oxidation of Fatty Acids, Beta- Oxidation of Fatty Acids

Reference Books

1 The physiology and Biochemistry of prokaryotes, 2nd edition By. David white

2 Outlines of biochemistry by Conn E. E. and Stumpf P. K. 4th Ed.

3 General microbiology by Stanier R.Y.: 5th Ed.

4 General microbiology by Powar and Daginawala Vol-1

5 Principles of Biochemistry By Lehninger

Unit III: Bioenergetics

3.1 Different modes of ATP generation

3.2 Electron transport chain : Introduction, Components of ETC and energy yield

3.3 Anaerobic Respiration

3.4 Methods of studying biosynthesis : Strategy of Biosynthesis, Use of Biochemical Mutants, Use of

Isotopic Labeling

3.5 Bacterial photosynthesis

3.6 Biosynthesis of peptidoglycan

Reference books

1 The physiology and Biochemistry of prokaryotes, 2nd edition By. David White

2 Outlines of biochemistry by Conn E.E. and Stumpt P.K. 4th Ed.

3 General microbiology by Stanier R.Y.: 5th Ed.

4 General microbiology by Powar and Daginawala Vol-1

Unit IV: Some Selected Aspects of Metabolism in Specific Microbial Systems

4.1 Chemo - autotrophs: Nitrifying Bacteria, Sulfur Oxidizers, The Iron bacteria, The Hydrogen Bacteria

4.2 The lactic acid bacteria: Patterns of carbohydrate fermentation in lactic acid bacteria

4.3 The Enteric group and related Eubacteria: Fermentative patterns of Gram negative Eubacteria

4.4 Archaebacteria: Energy metabolism and Carbon- Assimilation in Methanogens, photophosphorylation

in Halo bacterium

Reference Books

1 General Microbiology By Stanier R.Y.: 5th Ed.

2 The physiology and Biochemistry of prokaryotes, 2nd edition By. David

Unit V: Bacterial Membrane

5.1 Membrane lipids, Membrane carbohydrates, Membrane proteins, Membrane transport of small

molecules.

5.2 Specific Transport Systems : Mechanosensitive channels, ATP-binding cassette Transport family,

Chemiosmotic-driven transport, Establishing Ion gradients, Iron transport

5.3 The phosphotransferase system

5.4 Quorum sensing

5.5 Signal Transduction

Reference Books

1 General Microbiology By Stanier R.Y.: 5th Ed.

2 The physiology and Biochemistry of prokaryotes, 2nd edition by Devid

Practical

1 Determination of Vmax and Km for amylase enzyme by performing substrate curve with line weaver

Burk plot.

2 Determination of Vmax and Km for alkaline phosphatase by performing substrate curve with line

weaver Burk plot.

Reference Books

BSc Syllabus 2017-18 Semester V&VI Microbiology

1 International student edition: Microbiology- A laboratory Manual 4th edition. By James G. Chappuccino &

Natalie Sherman

2 Bacteriological Techniques By F.J. Baker

3 Introduction to Microbial Techniques By Gunasekaran.

SEMESTER - VI

MB-601: Immunology and Clinical Microbiology

Theory

Unit: I: Immunity and Immunogen

1.1 Types of immunity: Natural, Acquired, herd, Innate, specific

1.2 Cells and organs of immune system: An overview

1.3 Primary response and generation of memory

1.4 Antigen

a. Immunogenicity versus antigenicity

b. Factors influencing Immunogenicity

c. Adjuvant, Epitopes and Haptens

d. Antigen processing and presentation

Reference books

1. Immunology 5th edition J.Kuby, R. A. Goldsby , .J.Kindt , B.A. Osborne W.H. Freeman and

Company , New York

2. Principles of Microbiology- 2nd edition R.M.Atlas Wm.C.Brown Publishers

3. Microbiology 5th edition Prescott , Harley , Klein McGraw-Hill Publishers

4. Instant Notes in Microbiology P.M. Lyolyard , A. Whelan, M.W. Fanger

Unit II: Antigen and Antibody

2.1 Antibody

a. Basic structure of Antibody

b. Immunoglobulin classes and their Biological activities

c. Epitopes and Receptors on immunoglobulin molecule

d. Antibody Diversity and Clonal Selection Theory

e. Overview of Monoclonal Antibody

2.2 Strength of antigen antibody reaction: Antibody affinity and avidity

Reference books

1. Immunology 5th edition J.Kuby, R. A. Goldsby , T.J.Kindt , B.A. Osborne W.H. Freeman and

Company , New York

2. Principles of Microbiology- 2nd edition R.M.Atlas Wm.C.Brown Publishers

3. Microbiology 5th edition Prescott , Harley , Klein McGraw-Hill Publishers

4. Instant Notes in Microbiology P.M. Lyolyard , A. Whelan, M.W. Fanger

Unit III: Dysfunctional Immunity

3.1 Immunodeficiency Diseases

3.2 Hypersensitivity

3.3 Autoimmune diseases

3.4 Overview of Tumor immunity

3.5 Overview of Transplantation immunity

Reference books

1. Immunology 5th edition J.Kuby, R. A. Goldsby , T.J.Kindt , B.A. Osborne W.H. Freeman and

Company , New York

2. Principles of Microbiology- 2nd edition R.M.Atlas Wm.C.Brown Publishers

3. Microbiology 5th edition Prescott , Harley , Klein McGraw-Hill Publishers

4. Instant Notes in Microbiology P.M. Lyolyard , A. Whelan, M.W. Fanger

Unit IV: Infection and Prophylaxis

4.1 Introduction to the normal flora of healthy human host

4.2 Host microbe interactions

a. Process of Infection,

b. Pathogenicity

BSc Syllabus 2017-18 Semester V&VI Microbiology

d. Microbial adherence

e. Penetratation of epithelial cell layers,

f. Events in infection following penetration

g. Microbial virulence factors

4.3 Epidemiology of infectious disease: Markers, concepts and tools

4.4 Vaccines: Conventional and Modern

4.5 Microbial agent of Disease

a. Gram negative Bacteria Treponema, Salmonella, Shigella, E.coli ,Neisseria

b. Gram positive Bacteria Clostridium, Mycobacterium, Streptococci

c. Protozoa Amoebiosis, Malaria

Reference books

1. Immunology 5th edition J.Kuby, R. A. Goldsby , T.J.Kindt , B.A. Osborne W.H. Freeman and

Company , New York

2. Principles of Microbiology- 2nd edition R.M.Atlas Wm.C.Brown Publishers

3. Microbiology 5th edition Prescott , Harley , Klein McGraw-Hill Publishers

4. Instant Notes in Microbiology P.M. Lyolyard , A. Whelan, M.W. Fanger

1. Hematology

a. Discovery of human blood group system

b. Blood coagulation

c. Principle, significance and procedure of blood transfusion

2. Serology

A) In vitro antigen: antibody reaction

a. Precipitation (in fluid and gel, immunoelectrophoresis)

b. Agglutination (Haemagglutination , Bacterial Agglutination, Passive Agglutination and

agglutination inhibition)

c. Radioimmunoassay

d. ELISA

e. Western Blot

f. Immunofluoroscence

B) a. Methods of specimen collection

b. Identification of microbes from specimen

1) Microscopy

2) Rapid methods of identification

3) Molecular methods

Reference books

1 Immunology 5th edition J.Kuby, R. A. Goldsby , T.J.Kindt , B.A. Osborne W.H. Freeman and

Company , New York

2 Principles of Microbiology- 2nd edition R.M.Atlas Wm.C.Brown Publishers

3 Microbiology 5th edition Prescott , Harley , Klein McGraw-Hill Publishers

4 Instant Notes in Microbiology P.M. Lyolyard , A. Whelan, M.W. Fanger

Practical

1. Medical problem: Understanding of the problem and isolation & identification of microbes form clinical

specimen ( blood, urine, sputum, skin scraping, swabs, stool samples)

2. Antibiotic susceptibility of the pathogens isolated from the clinical specimen

3. Study of serological and hematological reactions

a. Agglutination ( blood grouping, serodiagnosis of enteric fever by Widal test)

b. Serodiagnosis of syphilis by RPR Test

c. Total count of RBC and WBC

d. Differential count of WBC

e. Haemoglobin estimation by Sahlis method

f. Bleeding time by filter paper technique and clotting time by capillary method

BSc Syllabus 2017-18 Semester V&VI Microbiology

4. Blood Chemistry

a. Blood sugar estimation by GOD / POD method

b. Blood urea by DAM method

c. Serum bilirubin (demonstration)

d. Cholesterol (demonstration)

5. Physical, chemical and microscopic analysis of urine

6. Microscopic study of pathogens ( permanent slides); Acid Fast Bacilli, Treponema, Malarial Parasite,

Entamoeba histolytic Clostridium tetanii, Neisseria species

Reference books

1 A Handbook of Practical and Clinical Immunology G.P.Talwar and S. K. Gupta CBS Publication

2 Medical Laboratory Technology Vol I , II , III Mukherji K.L.

3 A Text Book in Medical Laboratory Technology P.B.Godkar

4 Medical Bacteriology, Mycology and AIDS N.C. Dey, T.K. Dey, D.Sinha

Theory

Unit I: The History and Concept of Genetics

1.1 History of genetics and molecular biology

1.2 Mendelian Laws of inheritance The gene concept

1.3 Units of genetic structure and genetic function

1.4 Gene Cistron relationship in Prokaryotes and Eukaryotes

1.5 Gene structure and architecture

1.6 DNA is the universal genetic material

1.7 DNA Replication Mechanism and models

Reference Books

1 Advanced Molecular Biology, Twyman R. M.

2 Genes VII, Benjamin Lewin

3 Microbiology, Atlas R. M.

Unit II: Gene Expression and Regulation

2.1 Transcription and post transcriptional modifications

2.2 Genetic code and Ribosome

2.3 Translation and post translational modifications

2.4 Levels of gene expression and regulation

2.5 Types and principles of gene regulation

2.6 Transcriptional regulation

2.7 The Operon Model :Regulation of lactose utilization The lac operon

2.8 The Operon Model :Regulation of arabinose utilization The ara operon

2.9 The Operon Model :Regulation of tryptophan biosynthesis The trp operon

2.10 Post transcription control

Reference Books

1 Essential of Molecular Biology Malacinski G. M.

2 Advanced Molecular Biology Twyman R. M.

3 Molecular Genetics of Bacteria Synder L. & Champness

4 Microbial Genetics R. Maloy

5 Microbiology Prescott L. M.

6 Microbiology Atlas R. M.

Unit III: Gene Transfer and Recombination

3.1 Types of Recombination : Homologous recombination, Site specific recombination, Illegitimate

recombination,

3.2 Transformation: Natural transformation, competence, DNA uptake, role of natural transformation,

Artificial induced competence, electroporation

3.3 Transduction: Generalized transduction, specialized transduction and abortive transduction

3.4 Conjugation: Mechanism of DNA transfer in Gram positive and Gram negative bacteria

3.5 Transposable genetic elements

BSc Syllabus 2017-18 Semester V&VI Microbiology

Reference Books

1 Essential of Molecular biology Malacinski.G.M.

2 Advanced Molecular Biology Twyman R.M.

3 Molecular genetics of bacteria Synder L. & Champness

4 Microbial Genetics R. Maloy

5 Microbiology Prescott L.M.

6 Microbiology Atlas R.M.

Unit IV: Mutation and DNA Repair

4.1 Fluctuation analysis

4.2 Mutation and Mutation rate

4.3 Phenotypic effects of mutation, Phenotypic and Phenomic lag

4.4 Types of mutation :Spontaneous mutations and Induced mutations

4.5 Biochemical basis of mutation

4.6 Mutagenesis

4.7 Reversion and Ames test

4.8 DNA repair mechanisms - Mismatch repair, excision repair, photo reactivation,

Recombinational repair and SOS repair

Reference Books

1 Essential of Molecular biology Malacinski.G.M.

2 Advanced Molecular Biology Twyman R.M.

3 Molecular genetics of bacteria Synder L. & Champness

4 Microbial Genetics R. Maloy

5 Microbiology Prescott L.M.

6 Microbiology Atlas R.M.

Unit V: Genetic Engineering and Protein Engineering

5.1 Genetic engineering: aims and applications

5.2 Genetic manipulations of prokaryotes:

a. Isolation of DNA

b. Vectors of Recombinant-DNA Technology pBR 322, pUC, Bacteriophages, Cosmid, Phagmid,

BACs, YACs

c. Insertion of DNA molecules into a vector

d. Transformation and Growth

e. Detection of Recombinant molecules Colony Hybridization

f. Expression of foreign DNA

5.3 Genetic manipulations of eukaryotes: Genetic manipulation of plant cells, animal cells and yeasts

5.4 Site directed mutagenesis

5.5 Molecular Chaperons

5.6 Directed Evolution

Reference Books

1 Biotechnology Trevan M.D.

2 Advanced Molecular Biology Twyman R.M.

3 Microbiology Atlas R.M.

4 Microbiology Prescott L.M.

5 Microbial Genetics Freifilder. D

6 Principles of Gene Manipulation Old and Primrose

Practical

1 Isolation of DNA (only demonstration experiment)

2 Estimation of DNA

3 Conjugation in E.coli by plate method

4 Isolation of plasmid (Only demonstration experiment)

5 Transformation of plasmid

6 Isolation of RNA (only demonstration experiment)

7 Estimation of RNA

BSc Syllabus 2017-18 Semester V&VI Microbiology

9 Isolation of auxotrophic mutants by chemical mutagenesis (only demonstration experiment)

10 Isolation of antibiotic resistant bacterial population by gradient-plate method.

11 Isolation of streptomycin resistant mutants by Replica plating technique.

12 The Ames test: For detecting potential carcinogen (only demonstration experiment)

13 GFP cloning experiment ( Only demonstration experiment, Commercial teaching kits may be used to

demonstrate this experiment)

MB-603: Environmental Science

Theory

Unit I: Natural Resource

1.1 Introductions: Definition, Scope. Importance

1.2 Renewable and non-renewable resources

1.2.1 Natural resources and associated problems

1.2.2 Non-renewable resources

1.2.3 Renewable resources:

a. Forest Resources

b. Water Resources

c. Mineral Resources

d. Food Resources

e. Energy Resources

f. Land resources

Unit II: Ecosystems

2.1 Concept of an ecosystem

2.1.1 Understanding ecosystems

2.1.2 Ecosystem degradation

2.1.3 Resource utilisation

2.2 Structure and functions of an ecosystem

2.3 Producers, consumers and decomposers

2.4 Energy flow in the ecosystem

2.5 Ecological succession

2.6 Food chains, Food webs and Ecological pyramids

Unit III: Biodiversity and Its Conservation

3.1 Introduction Definition: genetic, species, ecosystem diversity

3.1.1 Genetic diversity

3.1.2 Species diversity

3.1.3 Ecosystem diversity

3.2 Threats to biodiversity

3.3 Conservation of biodiversity: in-situ and ex-situ

3.4 Biodiversity at global, national and local levels

3.5 India as a mega diversity nation

Unit: IV: Environmental Pollution

4.1 Definitions

4.2 Causes, effects and control measures of:

4.2.1 Air Pollution

4.2.2 Water Pollution

4.2.3 Soil Pollution

4.2.4 Marine Pollution

4.2.5 Noise Pollution

4.2.6 Thermal Pollution

4.2.7 Nuclear hazards

4.3 Solid waste management: causes, effects and control measures of urban and Industrial waste

4.4 Roles of individuals in pollution prevention

Unit V: Social Issues and the Environments

5.1 Climate change, global warming, acid rain, ozone layer depletion, nuclear accidents and nuclear

holocaust.

5.2 Environment protection act

BSc Syllabus 2017-18 Semester V&VI Microbiology

5.4 Forest conservation act

5.5 Issues involved in enforcement of environmental legislation and public awareness

5.6 Environment Impact Assessment (EIA)

5.7 What can I do?

Reference Books

1 Textbook for Environmental Studies For Undergraduate Courses of all Branches of Higher Education -

Erach Bharucha, for University Grants Commission

2 Agarwal KC, 2001. Environmental Biology, Nidi Publishers Ltd. Bikaner

3 Jadhav H and Bhosale VM, 1995. Environmental Protection and Laws. Himalaya Publishing House,

Delhi

4 Ecology and Environment P.D.Sharma

5 Odum EP, 1971. Fundamentals of Ecology. WB Saunders Co. USA,

MB-603: Environmental Science

Practical:

1 Chemical analysis of water: Chloride, Hardness, Nitrite Nitrogen, Alkalinity, Acidity, TDS, TSS, TS

2 Determination of air flora and air density from indoor & outdoor sources

3 Field Visit to Sewage treatment plant/Forest/Sanctuary/Soil Research Laboratory/GPCB Station and

preparation of report

4 Model Preparation as guided by faculty

- Physics I 2011-12Uploaded byArunava Samajpati
- UT Dallas Syllabus for math3312.501.11s taught by Mieczyslaw Dabkowski (mkd034000)Uploaded byUT Dallas Provost's Technology Group
- 1802.00227 - Is Quantum Mechanics Creationism, And Not ScienceUploaded byRzk-ro
- Wave Funtion and Born Interpretataion of Wave Function Plus Schrodinger Wave EquationUploaded byrabia_rabia
- Kinematics and Dynamics of Lower body of Autonomous Humanoid Biped Robot.docxUploaded byDeepak Bharadwaj
- Calc_Var.pdfUploaded byDiana Liza
- UT Dallas Syllabus for phys6400.001.09f taught by Joseph Izen (joe)Uploaded byUT Dallas Provost's Technology Group
- M.Sc. Mathematics syllabus 2017-19.pdfUploaded byBukera Aslam
- 033 - Pr 20 - Quartic LagrangianUploaded byBradley Nartowt
- Seminar PaperUploaded byLawrence Acob Eclarin
- Chapter 3Uploaded byBv Srikant
- lec10Uploaded byAnonymous 8f2veZf
- Resumen del capítulo 1 de Mecánica Clásica de Landau y LifshitzUploaded bypablo
- 3C25 Solid State Physics old notes 4 of 11 (UCL)Uploaded byucaptd3
- Constrained Multibody Dynamics With PythonUploaded byKevinPatrónHernandez
- Lesson Plan in Mathematics LuricaUploaded byMichelle Alejandrino
- Time Crystals From Minimum Time UncertaintyUploaded byforizsl
- 274802854-Engineering-Chemistry.pdfUploaded byJorn Doe
- Explanation of Abstract Algebra for Non MathematiciansUploaded byAhmed Haider
- Physics II SPUploaded byv
- A Group-Theoretic Construction With SpatiotemporalWavelets for the Analysis of Rotational MotionUploaded byss_barpanda8473
- Syllabus ITUploaded byManish
- BTech II Year Comp. Sc. & Engg. and Related Programs (Effective From 2017-18)Uploaded byYadav Deepankar
- A Classical Group of Neutrosophic Triplet GroupsUploaded byAnonymous 0U9j6BLllB
- AlgebraUploaded byHameed Khan
- Abstract Algebra Manual Problems and SolUploaded byRenata Malesevic
- Governing EquationsUploaded byrasyid93
- Bound QedUploaded byZaratustra Nietzche
- Milne Proof of Chevalley TheoremUploaded bybhaumiksaurav
- 2015 10 Sp Mathematics Sa1 Unsolved 03Uploaded byjagan

- The Shylock Show- Trial 3 Rules & Registration FormUploaded byChandraprakash Shah
- BSc III-IV Syllabus 2017-18 by Christ College - RajkotUploaded byChandraprakash Shah
- AQAR 2017-18Uploaded byChandraprakash Shah
- Top Alumni-Bioinformatics - Upto May 2018Uploaded byChandraprakash Shah
- Top Alumni-Bioinformatics - Upto May 2018Uploaded byChandraprakash Shah
- Top Alumni-Bioinformatics - Upto May 2018Uploaded byChandraprakash Shah
- Executive Summary Report MRPUploaded byChandraprakash Shah
- Felicitation 2017 18Uploaded byChandraprakash Shah
- BCA Syllabus 2017-18 By Christ College - RajkotUploaded byChandraprakash Shah
- BSc Bioinformatics Syllabus 2017-18 by Christ College - RajkotUploaded byChandraprakash Shah
- National Institutional Ranking Framework NIRF - 2017-18Uploaded byChandraprakash Shah
- BSc I-II Syllabus 2017-18 by Christ College - RajkotUploaded byChandraprakash Shah
- AQAR 2016-17Uploaded byChandraprakash Shah
- BCom Syllabus 2017-18 By Christ College - RajkotUploaded byChandraprakash Shah
- National Institutional Ranking Framework NIRF - 2016-17Uploaded byChandraprakash Shah
- The Shylock Show- Trial 3 Rules & Registration FormUploaded byChandraprakash Shah
- Creative Zone Inaugural CeremonyUploaded byChandraprakash Shah
- Cultural Week 2017Uploaded byChandraprakash Shah
- Top Alumni-Bioinformatics - Upto May 2018Uploaded byChandraprakash Shah
- Chrizellenz Rule Book-2017Uploaded byChandraprakash Shah
- BBA Syllabus 2017-18 By Christ College - RajkotUploaded byChandraprakash Shah
- BA Syllabus 2017-18 by Christ College - RajkotUploaded byChandraprakash Shah
- Felicitation 2015-2016Uploaded byChandraprakash Shah
- Felicitation 2016-2017Uploaded byChandraprakash Shah
- A Report On Gujarat Energy Development Agency (GEDA) Sponsored One Day Program On “Energy Conservation Awareness”Uploaded byChandraprakash Shah
- Orientation Program 2017Uploaded byChandraprakash Shah
- International Yoga Day 2017 CelebrationUploaded byChandraprakash Shah
- Felicitation 2013-2014Uploaded byChandraprakash Shah
- CIM Placement Brochure 2016-17Uploaded byChandraprakash Shah

- Chapter 8 Analysis of Differences in Species Composition 172Uploaded bySrivathsa Nallanchakravarthula
- 9781461495413-c1Uploaded byDiana Gil Vargas
- assesment 1Uploaded byASHUTOSH RAY 15BME0081
- BBET+TRE-2018-C-X-PAPER-1-AT+PCMUploaded bymsreddy86
- mm5docUploaded byKouider Moh
- Singular Value DecompositionUploaded byJohn Michael
- The Geometry of Discrete Groups (Alan F. Beardon)Uploaded bySaraya
- VectorsUploaded byDaniel Boenfie
- 12106_TPG1004g1Uploaded byJaismeer Singh
- Discriminant Analysis - MATLAB Classify - MathWorks IndiaUploaded byNamrata Singh
- MatlabSeminar MainUploaded byophank
- Appendix a MatlabTutorialUploaded byNick Johnson
- z7_0704Uploaded bym_zayan
- civilUploaded byapi-236544093
- Determinant Matlab ProjectUploaded byBrandon Simon
- Stone MethodUploaded byAnonymous RjJ7lCR
- SdtUploaded bytannguyenvan
- [Richard Bellman] Introduction to Matrix Analysis,(BookFi)Uploaded byPoil de Carotte
- Lecture Slides - Set 1Uploaded bySougata Roy
- m4l30 Lesson 30 The Direct Stiffness Method: Plane FramesUploaded byVitor Vale
- Introduction to MATLAB®Uploaded byqeddy
- MIMO Radar a Idea Whose Time Has ComeUploaded bytrongnguyen29
- Hipotesis de Riemann 151106Uploaded byJohn Battle
- On Matching Point ConfigurationsUploaded byAndrew Marrens
- cp1Uploaded byvamsi_4801762
- ENEE 660 HW Sol #3Uploaded byPeacefulLion
- 5.1 Structural Design BasisUploaded bylamki5436
- List of Experiments ItpUploaded byStrider_17
- Introduction to Parallel Programming_Student Workbook With Instructor's NotesUploaded byHoang Vu
- 1307.0803Uploaded byjuan perez arrikitaun