Disclaimer and Notices: The information and recommendations in this material is not intended as a substitute for personalized

medical advice. The material proposes certain theoretical models of nutrition not necessarily mainstream. It is left to the
discretion and it is the sole responsibility of the user of the information indicated in the material to seek the professional advice of
a licensed medical professional to determine if the procedures and recommendations described are appropriate for the patient. The
author of this information cannot be held responsible for the information or any inadvertent errors or omissions of the
information.

Information contained in this program is not intended to provide treatment for any disease, disability, or medical condition, or to
substitute for personal, individual medical care from a qualified physician. The reader is advised to check with his or her own
physician prior to following any recommendations given in this book, or any of its references. Every attempt has been made to
provide accurate information. However, the reader is on notice that the information in this book has been compiled and written
to address general principles. It is not intended as specific advice for any individual. Thus, the personal application of any
information provided herein is the sole responsibility of the user and, if implemented, would be applied at his or her own risk.

The information in these materials should not be construed as a claim or representation that any procedure or product mentioned
constitutes a specific cure, palliative or ameliorative. Procedures and products described should be considered as adjunctive to
other accepted conventional procedures deemed necessary by the attending licensed doctor.

It is the concern of the Department of Health and Human Services that no nutritional supplements be used to replace established,
conventional medical approaches, especially in cases of emergency, serious or life-threatening disease or conditions. The author
shares in this concern, as replacing conventional treatment with such remedies, especially in serious cases, may deprive the
patient of necessary treatment.

Intended Use Statement: The content of this course is intended for informational purposes only. The medical information in this
course is intended as general information only and should not be used in any way to diagnose, treat, cure, or prevent any disease.
The goal of this course is to present and highlight nutritionally significant information, and offer suggestions and protocols for
nutritional support and health maintenance. The information, including nutritional protocols and suggestions, is based on the
authors clinical experience and research, and is not intended to represent any claims regarding product performance.

Copyright 2012 by Ultimate Wellness Systems, Inc.

All rights reserved.

No portion of this manual may be used, reproduced, or transmitted in any form or by any means, electronic or mechanical,
including fax, photocopy, recording, or any information storage and retrieval system by anyone but the purchaser for their own
personal use. This manual may not be reproduced in any form without the express written permission of Ultimate Wellness
Systems, Inc., except in the case of a reviewer who wishes to quote brief passages for the sake of a review written for inclusion in a
magazine, newspaper, or journaland these cases require written approval from Ultimate Wellness Systems, Inc. prior to
publication.

For more information, please contact:

Prograde Nutrition
19239 N. Dale Mabry Hwy.
#154
Lutz, FL 33548
Phone: 1-888-943-8776
Web: http://helpdesk.getprograde.com/
http://www.getprograde.com/
 URGENT NOTICE

Social support is one of the most important factors of a successful cleansing

program. In fact, the membership area for this program you have just
purchased is far more valuable than the price you paid.

To get the most out of the cleanse possible be sure to ask questions, post your
experiences and just simply interact with other like-minded Prograde cleanse
customers interested in improving their health. This is an invaluable part of
your program and should be utilized to get the most from your experience.

I will be in the member's only area frequently answering questions to help

guide you along your way. Congratulations on making the decision to start
the cleanse process and taking much better control of your health!

- Dr. Bryan Walsh

Welcome to the post WWII world. We now live in an era of plastics, pesticides,
preservatives and perfumes. We put lotions, creams, shampoos, dyes, deodorant and
make-up on our body. In our homes we use Teflon pans to cook our food, air
fresheners to make things smell nice, a wide array of cleaning products to keep things
shiny. Our carpets, mattresses, shelves and computers all pour chemicals into the air.
We inhale toxic air when we drive, absorb toxic water when we shower and eat toxic
food that has a wide array of chemicals on it and in it designed to make it last longer on
the shelves and taste better when we eat it.

We live in a veritable chemical soup to which our planet has never seen before.
Interestingly, over the past four to five decades where tens of thousands of chemicals
are being released into our environment each year, so too have the number of
autoimmune diseases been rising. Its ironic that we are studying the effects of pollution
in our environment but few people seem to be concerned with the effects of pollution
on ourselves. There have been some recent studies, however, that have started to take a
critical look at how chemicals affect our physiology.

How Toxic Are We?

We are toxic. Pure and simple. Anyone that tells you otherwise does not know what
they are talking about.
Sixty years ago the concept of synthetic chemicals was largely science fiction. Since
then an estimated 90,000 manmade chemicals have been released into our environment,
with the vast majority of not being adequately evaluated with regard to human
physiology.

Were toxic. Pure and simple. Anyone that tells you

otherwise doesnt know what they are talking
about.

Numerous government and private party organizations have found vast amounts of
toxic substances in peoples body around the globe. Insecticides, PCBs, heavy metals,
benzene, dioxin, phthalates, pesticides, Teflon byproducts, DDT metabolites, flame
retardants, styrene, xylene and dichlorobenzene have been routinely found in the stool,
urine and blood of people around the globe, including newborn infants not yet exposed
to the outside world.

For example, some of these statistics are downright alarming:

In 2003, the Mount Sinai School of Medicine tested the blood and urine of people
from different areas in America and found that each person contained an average
of 91 industrial chemicals that included insecticides, PCBs, heavy metals (i.e.
mercury, cadmium), benzene and dioxin. None of the participants lived near an
industrial facility or worked in a job that handled chemicals.

In 2004, the Center for Disease Control and Prevention tested blood and urine
from 2,500 people across the country and found traces of all 116 chemicals they
tested for.

In 2005, the American Red Cross took samples of fetal cord blood from 10
newborns and found a shocking 287 chemicals in the samples. Included dioxins,
phthalates, pesticides, Teflon byproducts, flame retardants and many others.

A study published in the journal Neurotoxicology took samples of the first bowel
movement of 426 infants.
o 84% contained mercury
o 27% contained lead
o 27% percent had DDT, a pesticide that had been banned in the US for the
previous 25 years.

These chemicals are very new to our planet and to the human species. Many of these
chemicals have only been created in the last fifty years and the long term effects of them
are still relatively unknown. However it is safe to say that from what is known about
these toxins, we should work to decrease our exposure as much as possible, not only for
health, but for fat loss as well.

What is Detoxification?
Detoxification has become a buzz word in recent years and as such, it is difficult to
know what to believe when someone mentions a detox or cleansing program. In
fact, when many people hear the word detoxification they picture a washed-up junkie
or ex-celebrity going through drug rehab.

More recently however, many new age followers have been using the term
detoxification to mean colon cleansing, or some other silly practices, which entails
purging themselves by taking cathartic laxatives and leaves them on the toilet for hours.

This is not detoxification or cleansing.

What used to work for detoxification one hundred

years ago may no longer be safe today . . .

High-end medical spas are also becoming increasingly popular today and many of
them are offering detoxification and cleansing programs ranging from the very good to
the very dangerous. On the other end of the spectrum, even the average stay-at-home
mom today can jump online to find a variety of detoxification programs from juice fasts,
to parasite cleanses, to eating nothing but apples for a few days.

Again, the word detoxification has come to mean so many things.

At Prograde, we consider a good cleansing program to be one that is scientifically-based

and uses established principles in human physiology and metabolism. What used to
work for detoxification one hundred years ago may no longer be safe today due to the
bombardment of toxic chemicals, the high level of stress we are under and the beating
our physiology takes because of it.

That is why we came up with the program you hold in your hands today.
Our bodies continuously detoxify substances as a natural day-to-day function.
However, when you combine the toxic assault we are bombarded with in todays
modern world with excessive amounts of stress, along with poor nutrition and lack of
exercise, our bodies can no longer keep up and we begin to become overloaded, which
is often when symptoms begin to occur.

The History of Cleansing

Though detoxification has gained recent popularity and exposure, it has a long history
spanning many thousand years across many different parts of the world. Fasting, for
example, is one of the oldest therapeutic practices in medicine.

According to the oldest medical textbook ever discovered the Ebers Papyrus found in
Egypt from 4,000 years ago physicians were already using enemas to help the body
cleanse and combat disease. A while later in 400 B.C. the father of Western medicine,
Hippocrates, gave his patients cleansing herbs to help their body heal and was an
advocate of fasting for improving health. Ayurvedic medicine, considered to be one of
the oldest forms of medicine, has used detoxification for a wide range of chronic
conditions and to prevent illness.

Cleansing ones body has been around for a long time, and rightfully so. We produce a
number of toxic byproducts simply through the normal physiological processes of
digestion, metabolism, tissue regeneration, neuronal activity and various cellular
processes. Ammonia, for example, is something our body naturally manufactures and
needs to be cleared from our body.

We are also exposed to toxins from outside out body, which is a relatively new
phenomenon. At least to the degree we experience that today. These external toxins
include synthetic chemicals, pesticides, xenobiotics and even in otherwise healthy food
such as oxalic acid found in spinach.

The Great Processor: The Liver

The liver is responsible for a large number of functions in the body including protein
synthesis, production of chemicals required for digestion, storage of glycogen, break
down of red blood cells, hormone production and probably its most well-known
function, detoxification. For purposes of this publication, we will be focusing on the
last of those functions, detoxification, and how if it is not functioning properly, fat loss
will be difficult.

Healthy detoxification is critical for optimal health and fat loss for a number of reasons.
The liver has intimate connections with other systems of the body, including blood
sugar management, hormones, the gastrointestinal system and the immune system.
The liver is responsible for the metabolism and detoxification of a number of substances
in the body, including hormones and toxins.

In todays overly toxic environment, it is not uncommon to have a suboptimally

performing liver, resulting in a number of metabolic issues system wide. For example,
a defect in liver detoxification can lead to improperly metabolized hormones, leading to
hormone overload, imbalances and unhealthy hormone metabolites.

The liver has two distinct phases for detoxification and clearance, Phase I and Phase II.

The goal of liver detoxification is to transform fat-soluble compounds into water-soluble

compounds for elimination from the kidneys, skin (i.e. sweat) and stool. Fat-soluble
compounds include hormones, drugs, pesticides, and environmental chemicals. Phase I
detoxification involves a class of enzymes called the cytochrome P450 enzymes. After
having gone through Phase I, compounds can either be eliminated, or go through Phase
II.

One important point to note is that in many cases, when a toxin or molecule has gone
through Phase I conjugation, it becomes an intermediate compound capable of acting as
a free radical and causing damage to the body. In other words it becomes even more
toxic than the original compound being metabolized. Clinically this becomes relevant
when someone has upregulated Phase I activity in the liver and downregulated Phase II
capacities. These individuals, called pathological detoxifiers, will often have negative
reactions when exposed to toxic chemicals due to the number of free radicals produced
during Phase I detoxification.

Phase II detoxification in the liver has are six distinct pathways, each requiring its own
set of necessary compounds for optimal functioning. Proper functioning of these six
primary Phase II pathways include magnesium, potassium, vitamin C, some B vitamins
such as pantothenic acid, thiamin, folic acid and vitamin B12. It also requires certain
amino acids such as cystine, taurine, glycine, taurine, glutamine, arginine, ornithine,
methionine and glutathione.

Once a compound or toxin has been through Phase I and Phase II detoxification
pathways, it is combined with bile for elimination through the stool. Therefore if the
gall bladder, which stores bile, is not working properly, or if the large intestine is not
transporting stool properly (i.e. constipation), these toxins will not be properly
elimination and can negatively impact the body.
 Can Toxins Make Us Fat?
There is a new term floating around today called obesegens that was
created due to the strong correlation between certain chemicals and how they
seem to contribute to, or even cause, obesity.

Research Connecting Pesticides to Fat Gain

Small amounts of the pesticide, dieldrin, was given to rats, which lead to
a doubling of their body fat.

Another pesticide, hexachlorobenzene, caused rats to gain significant

body fat compared to a control group, even though the rats were eating
half as many calories.

Humans exposed to PCBs have shown that the greater the exposure to
PCBs, the greater the body fat.

Xenoestrogens found in our water and food supply cause a host of

estrogen-based hormonal issues, many of which lead to fat gain in human
and animal studies.

Synthetic chemicals were once used to be used to fatten up cattle for meat
production - animals fed organophosphates gain fat while eating less
food. While this practice is no longer used due to the toxic effects on the
animals themselves, organophosphates are still widely found in our
environment.

Numerous toxic chemicals used in our food supply negatively affect the
thyroid gland, slowing down metabolism and our ability to lose fat.

Some scientists believe that our body actually creates more fat to deal
with the load of environmental toxins we are exposed to. Because toxins
are so damaging to our sensitive cellular DNA, in an effort to protect
itself from these toxins, the body may add more storage by increasing the
amount of fat we have, and protect us from future damage by holding
onto the toxins by not letting us release them back into our system.

Research is somewhat new on this and it does not create an excuse for
why were overweight, but it is something that cannot be ignored.
 THE PROGRAM
The Prograde 72 Hour Cleanse is different from most other three day cleanses. In it we
apply our knowledge and understanding of physiology into creating the most well-
rounded and therefore likely most effective three day cleanse on the market today, with
no additional supplements necessary.*

*While supplements are not necessary, they may enhance the program. Specifically
Genesis, the Prograde greens drink has a number of different nutrients and compounds
that may add additional health benefits to the program.

You will be consuming approximately 64 ounces of fruit and vegetable juice daily, and
it is designed to be easy with minimal equipment necessary. All you need is a blender
and a trip to the grocery store to make it work.

The Rationale
Without going too deep into the science, here is the basis for what is included in the 3-
Day Cleanse program.

Fruit and Vegetable Juice

The process of eating food included digestion and absorption of nutrients.

Digestion is the breakdown of food into its smallest components and includes
things like chewing, mechanical mixing in our digestive tract, and digestive
enzymes to break down food as much as possible. Absorption is the actual
passing of nutrients from our digestive tract into our body.

Consuming the Pulp

Juicing is very popular today, but completely lacks the otherwise indigestible
fibers that come in fruits and vegetables. We think this is a mistake. Consuming
the fiber that comes with fruits and vegetables has a number of potential health
benefits, including:

1. Decreasing the glycemic response. Depending on the fruits and

vegetables used, if the juice is consumed alone, this can cause excess
surges in glucose, or blood sugar, which has a number of negative health
consequences. We want to try to stabilize blood sugar as much as possible
and the inclusion of the fruit and vegetable pulp may help with this.

2. Provide toxin removal. Cleansing programs are often high in nutrients,

but low in calories and overall food-based bulk. Our digestive system
needs a certain amount of bulk to help most things along our digestive
tract and to help bind toxins for elimination. Toxins that have been
metabolized in the liver end up in the digestive system for elimination. If
 this doesnt happen, the toxins can be reabsorbed back into us, which
obviously negates the benefits of a cleansing program.

3. Improve satiety. Juices are absorbed relatively quickly, leaving people

feeling hungry during a juice fast or cleansing program. The addition of
the fruit an d vegetable pulp can help decrease hunger sensations, making
the cleansing process much easier.

4. Fuel for bacteria. Some insoluble fibers are not absorbed by the human
digestive tract and actually make their way down the entire length of our
gastrointestinal system to our large intestines, where bacteria use it as fuel
to make healthy compounds such as short chain fatty acids. Cleansing
programs that do not incorporate fiber completely miss out on this very
important part of health promotion.

Water

One of the pathways for eliminating toxins is via the kidneys. Therefore if toxins
are being liberated during a cleanse, it is important to consume optimal amounts
of water to help clear and remove water-soluble toxins from the kidneys and the
body.

Fat

Most cleansing programs do not include fat, which we think is a mistake.

Studies have shown that the absorption of certain nutrients found in vegetables
is greatly increased when consumed with a fat source. Therefore to maximize
absorption of the many nutrients being consumed during the cleanse, we include
fat in the smoothies to enhance this process. Also, consuming fat may help with
satiety and feelings of hunger during the cleanse, making for a more comfortable
experience.

Also, when fat is consumed certain digestive hormones are triggered to stimulate
the release of bile from the gall bladder. Bile is released to help digest and
emulsify fats, but is also used to help remove fat-soluble toxins and substances
from the body. During a cleanse, if toxins are being released and detoxified in
the liver, bile secretion and elimination can help remove these toxic substances
from the body.

Lastly, some more traditional cleansing programs, such as Panchakarma found in

the Ayurvedic tradition, believe that the addition of fat helps in ridding toxins
from the body.

Sea Salt

Very few cleansing programs include the consumption of salt in their fruit and
vegetable juice. Again, this is likely a mistake. Sodium and electrolyte balance is
 critical for proper cellular function, which includes the assimilation of healthy
nutrients and elimination of unhealthy ones.

While this can be difficult for people to understand, it is possible to drink large
amounts of water but actually be dehydrated within our cells. Imagine raisins
versus grapes. The difference between the two is the amount of water contained
within them. When electrolyte imbalances exist, it is possible for water to stay
outside of our cells or even be worse, be pulled out of our cells, which is where
we need water most. Consuming small amounts of sea salt in the fruit and
vegetable smoothies may help prevent this from happening.

As an additional benefit, the inclusion of small amounts of sea salt may also help
improve the taste of the smoothies and somewhat reduce the amount of
urination that typically takes place during a cleanse.

Items Needed
- Blender
- Large 64oz bottle (or two to three 20-32oz bottles)

The Grocery List

Here are the following items you will need for the 3-Day Cleanse:

- Seven apples (fuji, gala, etc)

- One pound of carrots
- One bunch of celery
- One bunch of parsley
- 2 cups of nuts (almonds, cashews, walnuts, etc)
- 6 lemons
- 2 tomatoes
- One bulb of garlic
- One pineapple
- 2 Cucumbers
- One small cabbage
- One small bunch of broccoli
- One small head of cauliflower
- Three beets
- Two bunches of greens (spinach, kale, collard greens, etc)
 - Sea salt
- Two cans coconut milk
- One package fresh or frozen berries (blueberries, raspberries, strawberries, or a
mix of all three)
- Ginger (optional)
- Fresh mint (optional)

What To Do
Each day the goal is to make 64oz of a fruit and vegetable smoothie all at once, then
drink approximately 8oz every hour for 8 hours. In between the smoothie drinks, you
can consume herbal tea or water, with lemon added for taste if necessary.

Day One

Combine the following into a blender: three apples, one beet, two tomatoes, two carrots,
two celery stalks, two cucumbers, 1/3 pineapple, 2 cups cabbage, juice of two lemons,
cup coconut milk, cup nuts (almonds, walnuts, cashews)*, 1-3 garlic cloves**, -
tsp sea salt, fresh mint to taste.

Day Two

Combine the following into a blender: three apples, three large handfuls of greens (kale,
collard greens, spinach), one beet, three celery stalks, 2 handfuls of parsley, 2 cups
broccoli (or one cup of broccoli sprouts), 1/3 pineapple, juice of two lemons, cup
coconut milk, cup nuts (almonds, walnuts, cashews)*, 1-3 garlic cloves**, - tsp sea
salt, fresh mint to taste.

Day Three

Combine the following into a blender: three carrots, three celery stalks, one inch piece of
ginger (peeled), one beet, 2 cups cauliflower, 1/3 pineapple, 1 cup berries (blueberries,
strawberries, etc), one apple, juice of two lemons, cup coconut milk, cup nuts
(almonds, walnuts, cashews)*, 1-3 garlic cloves**, - tsp sea salt.

*Nuts soaked overnight will blend easier and are generally thought to be healthier than
raw, unsoaked nuts.

**Garlic has numerous health benefits but unfortunately some people find garlic to
negatively impact the taste of the smoothies. If this is the case for you, consider either
crushing the garlic into small pieces and chewing or directly swallowing the pieces, or
leaving out the garlic all together.

Additional Notes

The nutrients in fruits and vegetables are prone to oxidation and damage, and
therefore should be refrigerated during the day. Also salt and lemon juice are
included in each smoothie recipe, which may help decrease the amount of
oxidation until the juice is consumed.

In general it is a good idea to start by blending the more dense ingredients, such
as nuts, celery and broccoli, before adding the other less dense ingredients such
as pineapple and cucumbers.

Feel free to peel fruits and vegetables before blending, but if you dont, be sure to
thoroughly wash the vegetables first. Non-organic fruits and vegetables should
be peeled to reduce exposure to chemicals.

Organic produce is preferred but if certain ingredients are not available to you
locally, you can substitute where necessary. For example, if you cannot find
organic kale, organic spinach can be used instead.

As the smoothie sits in your refrigerator, it will likely become more sludgy then
when you first poured it in. Simply pour out approximately 8oz in to a large
glass and add as much water as is necessary to get the consistency you desire.

If youre used to drinking soda pop and juice bar smoothies, these smoothies
are going to taste different. Smoothies purchased at juice bars are designed to
taste good, not be healthy. If you want to sweeten the taste of the 72 Hour
Cleanse smoothies, you may experiment by adding small amounts of raw,
unprocessed honey to your smoothies. Limit it to no more than cup of honey
per daily smoothie batch.

If you have a small blender or you find it fills up before youre finished blending,
pour some of it off into a container, add the remaining ingredients, and mix the
final batch with the previous one in the bottle.

After the Cleanse

After three days of consuming fruit and vegetable smoothies, the last thing you want to
do is jump right back in to your typical way of eating. Therefore easing back into it is
highly recommended. Fortunately, the majority of people that do a cleanse find that
they have little desire for many of the processed foods they were consuming prior to the
cleanse.

The day after your cleanse has ended, consume only fruits, vegetables and nuts. You
will likely have some fruits and vegetables left over, and these can be freely consumed
as salads. You can also steam the vegetables with some salt and pepper, drizzled with
olive oil.

The second day after your cleanse, continue eating fruits and vegetables, but begin to
add in some light protein sources such as chicken, turkey bacon and egg whites.

Frequently Asked Questions

1. Id like to lose a few pounds. Will this program help me do this?

Although this program is not designed for weight loss, many people find they
lose a couple pounds while doing our cleansing regimen. Sometimes with
increased water intake, more efficient processing of toxins, eating a healthy
whole-food diet, reducing inflammation and avoiding food sensitivities, many
people improve their metabolism, which can result in weight loss.

2. What if I am constipated?

To properly do a cleansing program, you need to be having regular (daily or

more often) bowel movements. If you are not eliminating well, you may want to
add 400mg-800mg of magnesium to your program daily.

3. What if I cant find organic fruits and vegetables?

Fruits and vegetables that are consistently the most contaminated with pesticides
should be purchased organic. They are:

Apples Cherries Peaches Raspberries

Bell Peppers Grapes Pears Spinach
Celery Nectarines Potatoes Strawberries

If organic varieties are not available, fresh fruits and vegetables that consistently
have the lower levels of pesticides are the safest choices for conventionally
grown produce:

Asparagus Broccoli Kiwi Papaya

Avocado Cauliflower Mangos Pineapple
Bananas Corn (sweet) Onions Peas (sweet)

4. Is there anyone that should not do this detox?

Yes. This program is for relatively healthy people who want to look and feel
healthier. This program is not for anyone with serious health issues and is on
numerous medications. If you are taking certain medications or have a serious
medical condition, you must first talk with your doctor before doing this
program.
 5. Will it be uncomfortable?

There is bound to be differing opinions about the change in diet but this cleanse
is designed to be gentle and easy to follow. Remember, it is not a fast, nor is it a
colon cleanse, which are very harsh on your system. You will be consuming
nutrient-rich shakes to help support your body. Some people may feel a slight
withdrawal when they give up caffeine or sugar. But we have found this to be
the exception rather than the norm.

6. Will I be in the bathroom all day?

Due to the extra water and fluids that are consumed, many people urinate more
often than usual on this program. Additionally when people stop consuming
refined carbohydrates and sugar, many people report urinating more frequently
for a few days as fluids are being regulated differently.

7. Will I get headaches?

Some people experience headaches during a cleanse due to withdrawal from

sugar and caffeine. If this happens, you may drink green tea during the cleanse
to offer

8. Can I exercise?

If you are already exercising, you can continue to do so, though you might want
to decrease the intensity somewhat. If you find that you feel too fatigued, you
may want to limit yourself to gentle movement such as walking, stretching or
yoga.

9. Should I continue with my regular supplements?

If you are taking any medications, you must continue taking them unless
otherwise directed by your doctor. Vitamins and supplements can continue to
be taken as desired.

10. How often can I do this cleanse?

Many people like the benefits of the 3-Day Cleanse so much, they do it as often
as once a month.

Conclusion
By participating in the Prograde 3-Day Cleanse you have invested in the most
important asset you have - your health. If the wealthiest person in the world was in a
wheelchair and breathing on an oxygen tank, chances are he/she would be willing to
spend every dime to get their health back. Why wait until that point? By investing in
your health now you are taking the steps necessary to live a longer and healthier life.