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1st edition by Edward C. Klatt and Richard N. Mitchell

• Robbins and Cotran Pathology Flash Cards 1st edition by Edward C. Klatt and Richard N.

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The myocardial inflammatory lesions — called Aschoff bodies — are pathognomonic for rheumatic fever; these

The myocardial inflammatory lesionscalled Aschoff bodiesare pathognomonic for rheumatic fever; these are collections of lymphocytes (primarily T cells), scattered plasma cells, and plump activated macrophages called Anitschkow cells occasionally

punctuating zones of fibrinoid necrosis. The Anitschkow cells have abundant cytoplasm

and central nuclei with chromatin condensed to form a slender, wavy ribbon (so-called caterpillar cells). During acute rheumatic fever, Aschoff bodies can be found in any of the

three layers of the heartpericardium, myocardium, or endocardium (including valves).

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