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CD54 Endothelial cells ICAM-1 is a ligand for LFA-1, involved in strong ICAM-1
adhesion
CD56 NK cells 1. Adhesion molecule expressed by NK cells
2. CD56high NK cells are poorly cytotoxic but strong
secretors of cytokines
3. CD56low are the opposite
CD59 All "self" cells Inhibits the complement membrane attack complex by Protectin
binding C5b678 and preventing C9 from binding and
polymerizing
CD62E Endothelial cells Loosly bind to leukocytes (Sialyl-Lewis x) in venules, E-Selectin
resulting in a rolling adhesion
CD62L Naïve T cells Loosly bind to GlyCAM-1 in venules of lymphoid L-Selectin
tissues, resulting in a rolling adhesion
CD62P 1. Endothelial cells 1. Stored in granules Weibel-Palade bodies P-Selectin
2. Platelets 2. Loosly bind to leukocytes (Sialyl-Lewisx) in venules,
resulting in a rolling adhesion
CD69 T cells Earliest inducible cell surface glycoprotein acquired
during T cell activation
CD80+CD86 APC (Dendritic cells, 1. Binds to CD28 on T-cell to co-stimulate T-cell B7.1 & B7.2
macrophages) response to antigen binding
2. Without CD28/B7, T-cells become anergic on
binding to antigen
CD95 Endothelial cells VCAM-1 is a ligand for VLA-4, involved in strong Fas
adhesion
CD106 Endothelial cells VCAM-1 is a ligand for VLA-4, involved in strong VCAM-1
adhesion
CD127 IL-7 receptor α chain