Median eminence

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Not to be confused with Medial eminence.
Median eminence
HypothalamicNuclei.PNG
Median eminence is 'ME', at bottom-center, in light-green
Details
Identifiers
Latin eminentia mediana hypothalami
MeSH A08.186.211.730.385.357.352.435.249
NeuroNames hier-385
NeuroLex ID Median eminence
TA A14.1.08.409
FMA 74634
Anatomical terms of neuroanatomy
[edit on Wikidata]
The median eminence is part of the inferior boundary of the hypothalamus in the
human brain. A small swelling on the tuber cinereum posterior to the infundibulum
atop the pituitary stalk the median eminence lies in the area roughly bounded on
its posterolateral region by the cerebral peduncles, and on its anterolateral
region by the optic chiasm.

The median eminence is one of the seven areas of the brain devoid of a bloodbrain
barrier. It is sometimes considered one of the circumventricular organs.[1]

Physiology[edit]
The median eminence is a part of the hypothalamus from which regulatory hormones
are released. It is of great physiological importance, as it is integral to the
hypophyseal portal system, which connects the hypothalamus with the pituitary
gland. The pars nervosa (part of the posterior pituitary gland) is continuous with
the median eminence of the hypothalamus via the infundibular stalk. Parvocellular
neurons from the hypothalamus terminate in the median eminence of the hypothalamus.
To be specific, it is in the median eminence that the secretions of the
hypothalamus (releasing and inhibiting regulatory hormones, known as
"hypophysiotropic hormones") collect before entering the portal system. Such
hypophysiotropic hormones include: CRF (corticotropin-releasing factor), GnRH
(gonadotropin-releasing hormone), TRH (thyrotropin-releasing hormone), GHRH (growth
hormone-releasing hormone), and DA (dopamine). These hypophysiotropic hormones go
on to stimulate or inhibit the release of hormones from the anterior pituitary.

References[edit]
Jump up ^ Scott DE, Pepe GJ (July 1987). "The fetal baboon median eminence as a
circumventricular organ: I. Transmission electron microscopy". Brain Res. Bull. 19
(1): 8794. doi:10.1016/0361-9230(87)90170-5. PMID 3651843.
External links[edit]
http://thalamus.wustl.edu/course/hypo3.gif
[hide] v t e
Anatomy of the diencephalon of the human brain
Epithalamus
Surface
Pineal gland Habenula Habenular trigone Habenular commissure
Grey matter
Pretectal area Habenular nuclei Subcommissural organ
Thalamus
Surface
Stria medullaris of thalamus Thalamic reticular nucleus Taenia thalami
Grey matter/
nuclei
paired: AN Ventral VA/VL VP/VPM/VPL Lateral LD LP Pulvinar nuclei Metathalamus MG
LG P cell M cell K cell
midline: MD Intralaminar Centromedian Midline nuclear group Interthalamic adhesion
White matter
Mammillothalamic fasciculus Pallidothalamic tracts Ansa lenticularis Lenticular
fasciculus Thalamic fasciculus PCML Medial lemniscus Trigeminal lemniscus
Spinothalamic tract Lateral lemniscus Dentatothalamic tract Acoustic radiation
Optic radiation Subthalamic fasciculus Anterior trigeminothalamic tract
Medullary laminae
Hypothalamus
Surface
Median eminence/Tuber cinereum Mammillary body Infundibulum
Grey matter
Autonomic zones
Anterior (parasympathetic/heat loss) Posterior (sympathetic/heat conservation)
Endocrine
posterior pituitary: Paraventricular Magnocellular neurosecretory cell
Parvocellular neurosecretory cell Supraoptic oxytocin/vasopressin
other: Arcuate (dopamine/GHRH) Preoptic (GnRH) Suprachiasmatic (melatonin)
Emotion
Lateral Ventromedial Dorsomedial
White matter
afferent Medial forebrain bundle Retinohypothalamic tract efferent Mammillothalamic
fasciculus Stria terminalis Dorsal longitudinal fasciculus
Pituitary
Posterior is diencephalon, but anterior is glandular
Subthalamus
Subthalamic nucleus Zona incerta Nuclei campi perizonalis (Fields of Forel)
Categories: NeuroendocrinologyHypothalamus
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This page was last edited on 26 March 2017, at 04:42.
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