[KT 544] AUGUST 2008 Sub.

Code : 4065

SECOND M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations
Paper V – PHARMACOLOGY – I
Q. P. Code : 524065
Time : Three hours Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Essay Questions : (2 x 15 = 30)
1. (i) Classify antihypertensive drugs.
(ii) Write the mechanism of action and pharmacological action of captopril.
(iii) Therapeutic uses and adverse effects of captopril.
2. (i) Classify NSAID’s.
(ii) Write the mechanism of action and pharmacological action of salicylates.
(iii) Therapeutic uses and adverse effects of salicylates.

II. Write Short notes on : (10 x 5 = 50)

1. Treatment of organophosphorus poisoning.
2. Biotransformation.
3. Indications and contra – indications of B-blockers.
4. Write the differences between competitive & Non-competitive Neuromuscular blockers.
Write their therapeutic uses and adverse effects.
5. Intravenous general Anaesthetics.
6. Selective serotonin re-uptake inhibitors.
7. Pharmacotherapy of parkinsonism.
8. Therapeutic uses of prostoglandins.
9. High Ceiling Diuretics.
10. Pentazocine.

III. Short Answer Questions : (10 x 2 = 20)

1. Name two selective co x -2 inhibitors.
2. Rationale of giving adrenaline along with local anaestnetics.
3. Write two therapeutic uses of ONDANSETRAN.
4. Mention two advantages and disadvantages of sublingual route of drug administration.
5. Drug used in cardiogenic shock.
6. Centrally acting cough suppressants and their use.
7. Therapeutic uses of AMIODARONE.
8. Name two second generation Antihistamines and their therapeutic uses.
9. Therapeutic uses of organic nitrates.
10. Adverse effects of SPIRONOLACTONE.

*******
[KU 544] FEBRUARY 2009 Sub. Code : 4065

SECOND M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations
Paper V – PHARMACOLOGY – I
Q. P. Code : 524065
Time : Three hours Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Essay Questions : (2 x 15 = 30)
1. a) Classify Diuretics.
b) Write the mechanism of action and pharmacological actions of furosimide.
c) Therapeutic uses and adverse effects of Furosimide.
2. a) Classify sympathomimetic drugs.
b) Write the mechanism of action and pharmacological actions of adrenaline.
c) Therapeutic uses and adverse effects of adrenaline.

II. Write Short notes on : (10 x 5 = 50)

1. Carbamazepine.
2. Organic nitrates.
3. calcium channel blockers.
4. Succinyl choline.
5. Drug tolerance.
6. Uses and adverse effects of digoxin.
7. Atypical antipsychotics.
8. Define pharmacogenetics with two examples.
9. Tricyclic anti depressants.
10. Therapeutic uses of Lignocaine.

III. Short Answer Questions : (10 x 2 = 20)

1. Name two drugs used in trigeminal neuralgia.
2. Contra indications of adrenaline along with local anaesthetics.
3. Adverse effects of phenothiazines.
4. Therapeutic uses of alpha blockers.
5. Drugs used in status epilepticus.
6. Mention two drugs used in glaucoma with the rationale.
7. Mention two groups of drugs used in prophylaxis of migraine.
8. Treatment of methyl alcohol poisoning.
9. Mention two adverse effects of beta blockers.
10. Drugs used in anaphylactic shock.

*******
[KV 544] AUGUST 2009 Sub. Code : 4065

SECOND M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations
Paper V – PHARMACOLOGY – I
Q. P. Code : 524065
Time : Three hours Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Essay Questions : (2 x 15 = 30)
1. a) Classify Anti muscarinic drugs.
b) Mention pharmacological actions of atropine and its uses.
c) Enumerate atropine derivatives and its uses.
2. a) Classify H1 receptor blockers.
b) Pharmacology of mastcell stabilizers and its uses.
c) Enumerate H2 receptor blockers and its uses.

II. Write Short notes on : (10 x 5 = 50)

1. Bio availability.
2. Extra cardiac uses of β-blockers.
3. Enumerate calcium channel blockers write briefly on diltiazem.
4. Drug therapy of parkinsonism.
5. Neurolept – Analgesia.
6. Benzo diazepines.
7. Rationale of ethanol in methanol poisoning.
8. Quinidine.
9. Enumerate loop diuretics mention adverse effects.
10. Dopamine in cardiogenic shock.

III. Short Answer Questions : (10 x 2 = 20)

1. Name the two drugs eliminated through lungs.
2. Pre anaesthetic rationale of atropine.
3. Mention two uses of β-blockers.
4. Compare and contrast methylergometrine and oxytocin.
5. Dantrolene.
6. Mention two cardiac glycosides and two indications.
7. Mention two therapeutic uses of lignocaine.
8. Mention two drugs used as inhalation steroids two adverse effects.
9. Rationale of timolol in glaucoma.
10. Mention two selective cox-2 inhibitors and two adverse effects.

*******
[KW 544] FEBRUARY 2010 Sub. Code : 4065

SECOND M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations
Paper V – PHARMACOLOGY – I
Q. P. Code : 524065
Time : Three hours Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Essay Questions : (2 x 15 = 30)
1. a) Classify Anticonvulsant drugs.
b) Mechanism of action and pharmacological action of Benzodiazipines.
c) Therapeutic uses and adverse effects of Benzodiazipines.
2. a) Define Biotransformation reaction.
b) Explain phase I and phase II reaction with suitable examples.
c) Importance of Enzyme induction and enzyme inhibition.

II. Write Short notes on : (10 x 5 = 50)

1. Local routes.
2. Treatment of Glaucoma.
3. Balance anaesthesia.
4. Selective serotonin re-uptake inhibitors.
5. Osmotic diuretics.
6. Caverdilol.
7. Mechanism of action and uses of antiplatelet drugs.
8. Atarvostatin.
9. Iron preparations and uses.
10. Pre-anesthetic medication.

III. Short Answer Questions : (10 x 2 = 20)

1. Pro drug.
2. Rationale for use of dopamine in cardiogenic shock.
3. Therapeutic range.
4. Controlled release drugs.
5. Postural hypotension.
6. Zero order kinetics.
7. Mast cells modulators.
8. Mucolytic drugs.
9. Dissociative anesthesia.
10. COX – 2 Inhibitors.
*******
[KX 544] AUGUST 2010 Sub. Code : 4065

SECOND M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations
Paper V – PHARMACOLOGY – I
Q. P. Code : 524065
Time : Three hours Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Essay Questions : (2 x 15 = 30)
1. i) Classify antiepileptic drugs with examples for each group.
ii) Describe mechanism of action, adverse effects and therapeutic indications of
Diphenyl hydantoin.
iii) Role of Topiramate in epileptic patients.
2. i) Define drug and dose.
ii) Factors modifying drug action.

II. Write Short notes on : (10 x 5 = 50)

1. Classification and therapeutic uses of α (Alpha) – blockers.
2. Pharmacotherapy of migraine.
3. Thiazide diuretics – Mechanism of action, adverse effects and uses.
4. Drug therapy of chronic gout.
5. Heparin – mechanism of action, adverse effects and indications.
6. Therapeutic uses of prostaglandins.
7. Treatment of organophosphorus poisoning.
8. Drugs to be avoided in elderly and their safer alternatives.
9. Treatment of Myocardial infarction.
10. Enumerate statins. Write about mechanism of action and indications of statins.

III. Short Answer Questions : (10 x 2 = 20)

1. Mention four drugs bound to plasma albumin.
2. What is Rupatadine? Mention one indication for it.
3. Mention two Leukotriene antagonists used in bronchial asthma.
4. What is fomepizole? Mention one indication for it.
5. Mention any four preanaesthetic medicants.
6. Mention four angiotensin receptor blockers.
7. Drugs used in anaphylactic shock.
8. Mention two non benzodiazepine hypnotics.
9. Mention two selective dopamine agonists used in Parkinson’s disease.
10. Give two examples for physiological functional antagonism.

*******
[KY 544] FEBRUARY 2011 Sub. Code : 4065

SECOND M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations
Paper V – PHARMACOLOGY – I
Q. P. Code : 524065
Time : Three hours Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Essay Questions : (2 x 15 = 30)
1. (i) Classify adrenergic drugs.
(ii) Discuss the therapeutic uses of adrenergic drugs.
(iii) Outline the adverse effects and contraindications of Adrenaline.
2. (i) Classify antihypertensive drugs.
(ii) Discuss the mechanism of action & therapeutic uses of Angiotensin receptor blockers.
(iii) Outline briefly about hypertensive emergencies and urgencies.

II. Write Short notes on : (10 x 5 = 50)

1. Newer drug delivery system.
2. Therapeutic uses of atropine and its substitutes.
3. Therapeutic uses of H1 antihistaminics.
4. Centrally acting skeletal muscle relaxants.
5. Complications of spinal anaesthesia.
6. Phenytoin sodium.
7. Amiodarone.
8. Flurosemide.
9. Heparin.
10. Mast cell stabilizers.

III. Short Answer Questions : (10 x 2 = 20)

1. Mention four drugs delivered by transdermal patches.
2. Define Plasma half life. Mention two drugs with long Plasma half life.
3. Mention four methods of prolongation of drug action.
4. What is competitive antagonism?
5. Define Teratogenicity. Mention four Teratogenic drugs.
6. Mention four drugs used in the treatment of Glaucoma.
7. Mention four therapeutic uses of Prostaglandins.
8. Mention four contraindications for Aspirin.
9. Give four examples for DMARDs.
10. Mention four examples for HMG – CoA reductase inhibitors.

********
[KZ 544] AUGUST 2011 Sub. Code : 4065

SECOND M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations
Paper V – PHARMACOLOGY – I
Q. P. Code : 524065
Time : Three hours Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Essay Questions : (2 x 15 = 30)
1. (i) Enumerate the various sedative and hypnotic drugs.
(ii) Discuss the mechanism of action, uses and adverse effects of benzodiazepines.
(iii) Briefly discuss the management of acute barbiturate poisoning.
2. (i) Classify anticholinersterases
(ii) Discuss the mechanism of action and indications of reversible anti-cholisterases
(iii) Outline the management of acute organophosphorous poisoning.

II. Write Short notes on : (10 x 5 = 50)

1. Mydriatics.
2. Drugs used in prophylaxis of migraine.
3. Receptor antagonism of drugs.
4. Sublingual route of administration.
5. Blood-Brain barrier.
6. Therapeutic uses of loop diuretics.
7. Parenteral iron therapy.
8. Epsilon amino-caproic acid.
9. Therapeutic uses of prostaglandin analogues.
10. Uricosuric agents.

III. Short Answer Questions : (10 x 2 = 20)

1. Mechanism of action of Disulfiram.
2. What is potentiation of drug action? Mention two examples?
3. What is Eutetic mixture? Mention its indications.
4. Mention two uses, two advantages and two disadvantages of thiopentone sodium.
5. What is first order kinetics?
6. What is fixed dose combination? Give two examples
7. Mention two selective Cox-2 inhibitors. What are the advantages?
8. What are antitussives? Give two examples.
9. Mention 2 thiazide diuretics. Mention two uses of thiazides.
10. What is the mechanism of action and uses of Montelukast?

*******
[LA 544] FEBRUARY 2012 Sub. Code : 4065

SECOND M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations
Paper I – PHARMACOLOGY – I
Q. P. Code : 524065
Time : 180 Minutes Maximum: 40 Marks
Answer ALL questions in the same order.
Draw Suitable diagrams wherever necessary
I. Elaborate on :
1. a) Classify β blockers.
b) Discuss the pharmacological actions, kinetics, adverse effects and Usesof propronalol.
c) Mention the role of beta blockers in thyrotoxicosis. (10 x 1 = 10)
2. a) Classify antiepileptic drugs.
b) Discuss in detail about the mechanism of action, kinetics, adverse effects
and uses of phenytoin.
c) How will you manage a known epileptic with three months of enorrhoea.(5 x 1 = 5)

II. Write notes on : (10 x 1.5 = 15)

1. Essential drugs
2. Microsomal enzyme inducers
3. Antagonism
4. Pre anesthetic medication
5. Therapeutic uses of morphine
6. Treatment of Alzheimers disease
7. Glyceryl trinitrate
8. Inhaled steroids
9. Lignocaine
10. Osmatic diuretics.

III. Short Answers on : (10 x 1 = 10)

1. Define pharmacogenomics
2. Orphan drugs
3. Mechanism of action of digoxin
4. Loading dose
5. First dose effect
6. Name two sialogoges
7. Drugs used in acute gout
8. Mention four Atypical anti psychotics
9. Mention two uses of Dinoprostone
10. Name two central sympatholytic agents write two uses.

*******
[LB 544] AUGUST 2012 Sub. Code : 4065

SECOND M.B.B.S. DEGREE EXAMINATION

Paper I – PHARMACOLOGY – I
Q. P. Code : 524065
Time : 180 Minutes Maximum: 40 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Elaborate on: Pages Time Marks
(Max.) (Max.) (Max.)
1. a. Classify the drugs used as peripherally acting skeletal
muscle relaxants. 16 30 10
b. Discuss in detail the pharmacological actions and
toxicity produced by d-Tubocurarine.
c. Add a note on the rationale of using Dantrolene sodium
in the management of Malignant Hyperthermia.
2. Discuss the role of sympathomimetics in the management 8 20 5
of Bronchial asthma.

II. Write notes on:

1. Drug responses in elderly. 3 8 1.5
2. Uroselective α adrenergic blockers. 3 8 1.5
3. Selective 5-HT 1B/1D agonist. 3 8 1.5
4. Mechanism of action and uses of Nimesulide. 3 8 1.5
5. Propofol as an inducing agents. 3 8 1.5
6. Role of Ethyl alcohol in Methyl alcohol poisoning. 3 8 1.5
7. Management of Status Epilepticus. 3 8 1.5
8. Malignant Neuroleptic Syndrome. 3 8 1.5
9. Contraindications for Digitalis use. 3 8 1.5
10. Mechanism of action and uses of Spironolactone. 3 8 1.5

III. Short answers on:

1. Citrovorum factor rescue. 2 5 1
2. Heparin Antagonist. 2 5 1
3. 4 extravascular uses of Clonidine. 2 5 1
4. Physiological Antagonism. 2 5 1
5. Dopaminergic agonist in Parkinsonism. 2 5 1
6. Uses of Diazepam. 2 5 1
7. Contraindications for β blockers. 2 5 1
8. Mechanism of action and uses of Nitrendipine. 2 5 1
9. Consequences of Microsomal inhibition. 2 5 1
10. Bupivacaine. 2 5 1
*******
[LC 544] FEBRUARY 2013 Sub. Code : 4065

SECOND M.B.B.S. DEGREE EXAMINATION

Paper I – PHARMACOLOGY – I
Q. P. Code : 524065
Time : 180 Minutes Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Elaborate on: (2 x 15 = 30)
1. a. Classify adrenergic drugs based on therapeutic uses.
b. Discuss about the pharmacological action adverse effects and uses of adrenaline.
2. a. Classify antiparkinsonian drugs.
b. Write about on Dopaminergic agonists.

II. Write notes on : (10 x 5 = 50)

1. Fixed dose ratio combinations.
2. Newer drug delivery system.
3. Pentazocine.
4. Potassium channel Openers.
5. Therapeutic use of atropine.
6. Adverse effect of high ceiling diuretics.
7. Mention the various Iron Preparation.
8. Seletive serotonin Reuptake inhibitors.
9. Venodilators.
10. Metachlopromide.

III. Short Answers on: (10 x 2 = 20)

1. What is cumulation.
2. Drug therapy for vertigo.
3. Omalizumab.
4. Therapeutic Index.
5. Modafinil.
6. Amakacin.
7. Uses Erthropoietin.
8. Name four Angiotensin Receptor blockers.
9. Esmolol.
10. Mention four adverse effects of Phenytoin.

*******
[LD 544] AUGUST 2013 Sub. Code : 4065

SECOND M.B.B.S. DEGREE EXAMINATION

Paper I – PHARMACOLOGY – I
Q. P. Code : 524065
Time : 180 Minutes Maximum: 40 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Elaborate on: (2 x 7.5 = 15)
1. a) Classify the drugs used for the treatment of Parkinsonism.
b) Discuss the Pharmacological actions, Adverse effects & Interactions of Levodopa.
2. Discuss the drug therapy of Anticholinesterase poisoning.

II. Write Notes on: (10 x 1.5 = 15)

1. Specialized active transport mechanism across biological membrane.
2. Beneficial effects of β blockers in Myocardial infarction.
3. Topiramate.
4. Effects of Aspirin on acid base & electrolyte balance.
5. Mucokinetic agents.
6. Local anaesthetics in the presence of inflammation.
7. Aldehyde dehydrogenase inhibitor.
8. Agents inhibiting Renin-Angiotensin system.
9. Pharmacovigilance.
10. Glycoprotein IIb/IIIa receptor antagonist.

III. Short Answers on: (10 x 1 = 10)

1. 2 merits & 2 demerits of rectal administration of drugs.
2. Sibutramine.
3. Advantages of topical β blockers over miotics in Glaucoma.
4. Uses of Cyproheptadine.
5. Name 2 Leukotriene receptor antagonists & their indications.
6. Thiazides as Antidiuretics.
7. Azelastine.
8. Adenosine in the management of Paroxysmal Supra Ventricular Tachycardia.
9. What are LMW Heparins & enumerate their advantages over regular Heparin.
10. Serotonin and Noradrenaline Reuptake Inhibitors (SNRI).

*******
[LE 544] FEBRUARY 2014 Sub. Code: 4065

SECOND YEAR MBBS DEGREE EXAMINATION

Paper I – PHARMACOLOGY – I
Q. P. Code: 524065
Time : 180 Minutes Maximum: 40 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Elaborate on: (2 x 7.5 = 15)
1. a) Classify Diuretics
b) Discuss the mechanism of action, therapeutic uses and complications of
Frusemide.
2. a) Classify antianginal drugs.
b) Discuss the mechanism of action and therapeutic uses of Glyceryl trinitrate.

II. Write Notes on: (10 x 1.5 = 15)

1. Drug therapy in myocardial infarction
2. Complications of General anaesthesia.
3. Therapeutic uses of prostaglandins
4. Sodium valproate.
5. Aectazolamide
6. Pre anaesthetic medication.
7. Management of status asthmaticus.
8. Therapeutic uses of cholinergic drugs.
9. Osmotic diuretics
10. Therapeutic uses of atropine and its substitutes

III. Short Answers on: (10 x 1 = 10)

1. Mention four antiasthmatic drugs
2. Enumerate four routes of drug administration
3. Mention four anti psychotic drugs.
4. Define anaphylaxis with a suitable example.
5. Mention four contraindication for morphine
6. Mention four drugs for Gout.
7. Give two examples of drugs administered by Transdermal route.
8. Enumerate the methods for prolongation of drug action.
9. Explain physiological antagonism with one example
10. Treatment of drug allergy

*******
[LF 544] AUGUST 2014 Sub. Code: 4065

SECOND YEAR M.B.B.S DEGREE EXAMINATION

Paper I – PHARMACOLOGY - I
Q. P. Code: 524065
Time: Three Hours Maximum: 40 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Elaborate on: (2 x 7.5 = 15)
1. Define Biotransformation.
Describe briefly the various biotransformation reactions.
2. Enumerate antiepileptic drugs.
Discuss the pharmacology of drugs acting on GABA receptors.

II. Write Notes on: (10 x 1.5 = 15)

1. Selective serotonin reuptake inhibitors
2. Opioid receptors
3. Ipratropium bromide
4. Ocular hypotensives
5. Sumatriptan
6. Treatment of acute gout
7. Class 3 antiarrhythmics
8. Losartan
9. Bromocriptine
10. COX-2 inhibitors

III. Short Answers on: (10 x 1 = 10)

1. Drug potency vs efficacy
2. What is iatrogenic disease. Give 2 EXAMINATIONples
3. Eutectic mixture
4. Cholinergic crisis
5. Ebastine
6. Treatment of acute paracetamol poisoning
7. Ondansetron
8. What are the antihypertensives to be avoided in pregnancy. Give reasons
9. Contraindications of heparin
10. Uses of acetazolamide.

*******
[LG 544] FEBRUARY 2015 Sub.Code :4065

M.B.B.S. DEGREE EXAMINATION

SECOND YEAR
PAPER I – PHARMACOLOGY I

Q.P. Code: 524065

Time: Three hours Maximum : 40 Marks
Answer All Questions
I. Elaborate on: (1 x 10 = 10)

1. Classify Non-steroidal anti inflammatory drugs. Write the mechanism of

action, pharmacological actions, therapeutic uses and adverse effects of
Salicylates.

II. Write notes on: (4 x 5 = 20)

1. Drug therapy of Parkinsonism

2. Mechanism of action and uses of antiplatelet drugs
3. Pharmacotherapy of migraine
4. Mechanism of action of Phenytoin

III. Short answers on: (5 x 2 = 10)

1. Cholinesterase reactivators in organophosphorus poisoning

2. Heparin versus warfarin
3. Role of glucocorticoids in bronchial asthma
4. Drug therapy for chronic gout
5. Mechanism of action of d-tubocurarine

********
[LH 544] AUGUST 2015 Sub. Code: 4065

SECOND M.B.B.S. DEGREE EXAMINATION

PAPER I – PHARMACOLOGY - I
Q.P. Code: 524065
Time : Three Hours Maximum : 40 marks
Answer ALL questions
I. Elaborate: (1 x 10 = 10)
1. Discuss various factors modifying a drug’s actions.
Write briefly about Pharmacogenetics.

II. Write notes on : (4 x 5 = 20)

1. Atypical antipsychotics.

2. Salbutamol.

3. Dicyclomine.

4. Spironolactone.

III. Short answers on : (5 x 2 = 10)

1. Nimesulide.

2. Name four antiarrythmics.

3. Name four peripherally acting skeletal muscle relaxants.

4. Ketorolac.

5. Four adverse effects of furosemide.

*******
[LI 544] FEBRUARY 2016 Sub. Code: 4065

SECOND YEAR M.B.B.S. DEGREE EXAMINATION

PAPER I – PHARMACOLOGY - I
Q.P. Code : 524065
Time : Three Hours Maximum : 40 Marks
Answer ALL questions
I. Elaborate on: (1 x 10 = 10)
1. Classify Sedative - Hypnotics. Discuss the mechanism of action, uses and
adverse effects of Benzodiazepines. Write briefly on Flumazenil.

II. Write notes on: (4 x 5 = 20)

1. Pharmacovigilance.

2. Bromhexine.

3. Nasal decongestants.

4. Sodium nitroprusside.

III. Short answers on: (5 x 2 = 10)

1. Mention four uses of aspirin.

2. Mention four uses of furosemide.

3. Succinylcholine apnoea.

4. Types of synergism.

5. Uses of mast cell stabilizers.

*******
[LJ 544] AUGUST 2016 Sub. Code : 4065

SECOND YEAR M.B.B.S. DEGREE EXAMINATION

PAPER I – PHARMACOLOGY - I
Q. P. Code : 524065
Time : Three hours Maximum: 40 Marks
Answer ALL questions.
I. Elaborate on : (1 x 10 = 10)
1. Classify beta blockers. Mention the advantages of selective over non selective beta
blockers. Discuss the adverse effects of beta blockers.

II. Write notes on: (4 x 5 = 20)

1. Therapeutic uses of alpha blockers.

2. Mechanism of action of disulfiram.

3. Mechanism of action and therapeutic uses of digoxin.

4. Enumerate statins. Write about mechanism of action and indications for statins.

III. Short answers on: (5 x 2 = 10)

1. Potassium sparing diuretics.

2. First pass metabolism with suitable example.

3. Mechanism of action of tramadol.

4. Methanol poisoning.

5. Treatment of Glaucoma.

*******
[LK 544] FEBRUARY 2017 Sub.Code :5061

M.B.B.S. DEGREE EXAMINATION

SECOND YEAR
PAPER I – PHARMACOLOGY – I

Q.P. Code: 525061

Time: Three hours Maximum : 40 Marks
Answer All Questions
I. Elaborate on: (1 x 10 = 10)

1. Classify antianginal drugs. Discuss the mechanism of action, uses and adverse
effects of nitrates.

II. Write notes on: (4 x 5 = 20)

1. Mechanism of action, uses and adverse effects of sodium valproate.

2. Management of organophosphorus poisoning.
3. Mechanism of action, uses and adverse effects of ketorolac.
4. Enumerate and discuss the role of inhaled steroids in bronchial asthma.

III. Short answers on: (5 x 2 = 10)

1. Write four therapeutic uses of prostaglandins.

2. Give two reasons for using morphine in left ventricular failure.
3. Define plasma half life. Give two examples of drugs with short half life.
4. Write two indications and two adverse effects of thiazides.
5. What is phase IV clinical trial?

********
 [LL 544] AUGUST 2017 Sub.Code :5061

M.B.B.S. DEGREE EXAMINATION

SECOND YEAR
PAPER I – PHARMACOLOGY – I

Q.P. Code: 525061

Time: Three hours Maximum : 40 Marks
Answer All Questions
I. Elaborate on: (1 x 10 = 10)

1. Classify drugs used in the treatment of parkinsonism. Explain the mechanism of

action and adverse effects of levodopa. What is the rationale for use of carbidopa
with levodopa? Write briefly on selegiline.

II. Write notes on: (4 x 5 = 20)

1. Pharmacogenetics.
2. Thiazide diuretics.
3. Adrenaline.
4. Inhalational corticosteroids.

III. Short answers on: (5 x 2 = 10)

1. Mention four antitussive drugs.

2. Name four anti-platelet drugs.
3. Mention four drugs used in migraine prophylaxis.
4. Serotonin syndrome.
5. Tachyphylaxis.

********
[KT 545] AUGUST 2008 Sub. Code : 4066

SECOND M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations
Paper VI – PHARMACOLOGY – II
Q. P. Code : 524066
Time : Three hours Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Essay Questions : (2 x 15 = 30)
1. a. Classify anti malarial drugs.
b. Mechanism of action and Pharmacological actions of chloroquine.
c. Therapeutic uses and adverse effects of chloroquine.
2. a. Classify macrolide antibiotics.
b. Write the mechanism of action and Anti bacterial spectrum of Erythromycin.
c. Therapeutic uses and adverse effects of Erythromycin.

II. Write Short notes on : (10 x 5 = 50)

1. Prokinetic drugs.
2. Drugs used in Bronchial Asthma and Write different techniques of Administration.
3. Fibrinolytic agents.
4. Tocolytic agents.
5. Alkylating agents and Therapeutic uses.
6. Retoconazole
7. Uricosuric Drugs.
8. Anti-Retroviral Drugs.
9. Doxycycline and their advantages over tetracylines.
10. Flouroquinolones and their Therapeutic uses.

III. Short Answer Questions : (10 x 2 = 20)

1. Adverse effects of Aminoglycosides.
2. Name two immunosuppresants and their uses.
3. Ivermectin Therapeutic uses.
4. Name two Anticancer antibiotic and write their therapeutic uses.
5. Name drugs of Third generation cephalosporin.
6. Dimercaprol.
7. Radio-active iodine.
8. Adverse effects of oral contraceptive pills.
9. Triple drug regime of peptic ulcer.
10. New routes of drug delivery system of insulin.

*******
[KU 545] FEBRUARY 2009 Sub. Code : 4066

SECOND M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations
Paper VI – PHARMACOLOGY – II
Q. P. Code : 524066
Time : Three hours Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Essay Questions : (2 x 15 = 30)
1. a. Classify penicillin group of antibiotics.
b. Write the mechanism of action and anti bacterial actions of aminopenicillins.
c. Therapeutic uses and adverse effects of ampicillin.
2. a. Classify anti amoebic drugs.
b. Write the mechanism of action and anti protozoal actions of Metronidazole.
c. Therapeutic uses and adverse effects of Metronidazole.

II. Write Short notes on : (10 x 5 = 50)

1. Clarithromycin.
2. Mechanism and pharmacological actions of sulfonyl ureas.
3. Anti motility drugs.
4. Desferrioxamine.
5. Primaquine.
6. Ketoconazole.
7. Indications and adverse effects of oral contraceptive pills.
8. Rifampicin.
9. Uses and adverse effects of anabolic steroids.
10. Ovulation inducing agents.

III. Short Answer Questions : (10 x 2 = 20)

1. Uses and toxicity of quinine.
2. Name two drugs used in motion sickness with the rationale.
3. Mention four 2nd generation cephalosporins.
4. Rationale of combining aluminium and magnesium salts in antacids.
5. Mention two anticancer antibiotics with their indication.
6. Mechanism of action of radio active iodine.
7. Name two drugs used in scabies with their route of administration.
8. Mention four inhalational corticosteroids.
9. Specific adverse effects of fluoroquinolones.
10. Mention two alpha glucosidase inhibitors and indication.

*******
[KV 545] AUGUST 2009 Sub. Code : 4066

SECOND M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations
Paper VI – PHARMACOLOGY – II
Q. P. Code : 524066
Time : Three hours Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Essay Questions : (2 x 15 = 30)
1. a. Classify drugs used in diabetes mellitus.
b. Write the mechanism of action, uses of oral hypoglycemic drugs.
c. Enumerate DNA recombinant derived insulins.
2. a. Define aminoglycoside antibiotics and enumerate them.
b. Mechanism of action, common adverse effects of aminoglycosides.
c. Write the therapeutic uses of gentamicin.

II. Write Short notes on : (10 x 5 = 50)

1. Third generation cephalosporins.
2. Drug regimen in H.Pylori.
3. Indications and contra indications of glucocortocoids.
4. Extra malarial uses of chloroquine and its rationale.
5. Anti thyroid drugs.
6. Oral contraceptives.
7. Define chemoprophylaxis give examples with rationale.
8. Pro kinetic drugs.
9. Sucralfate.
10. Repository preparations of penicillins.

III. Short Answer Questions : (10 x 2 = 20)

1. Tetracyclines not used in young children – Why?
2. Two uses of D-Penicilamine.
3. Mention two topically used sulfonamides and its uses.
4. Ondensetran as an antiemetic in cancer chemo therapy.
5. Monoclonal antibodies as carriers.
6. Two uses and two adverse effects of vitamin-D.
7. Rationale of L-Asparginase in malignancy.
8. Mention two tocolytic agents and its uses.
9. Therapeutic use and its rationale of finasteride.
10. Two indications of mebendazole.

*******
[KW 545] FEBRUARY 2010 Sub. Code : 4066

SECOND M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations
Paper VI – PHARMACOLOGY – II
Q. P. Code : 524066
Time : Three hours Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Essay Questions : (2 x 15 = 30)
1. a) Classify anti tubercular drugs.
b) Mechanism of action and bacterial spectrum of action of rifampicin.
c) Explain short course treatment of tuberculosis.
2. a) Classify dopamine receptors and mention its agonists and antagonists.
b) Write mechanism of action and pharmacological actions of metaclopramide.
c) Therapeutic uses and adverse effects of metaclopramide.

II. Write Short notes on : (10 x 5 = 50)

1. Proton pump inhibitors.
2. Amikacin.
3. Doxycycline.
4. Bacterial resistance.
5. Chloroquine.
6. Carbimazole.
7. Combined pill.
8. Hormone replacement therapy.
9. Fluconazole.
10. Cyclosporin.

III. Short Answer Questions : (10 x 2 = 20)

1. DHF reductase inhibitors.
2. Antianerboic antibiotics.
3. Framycetin.
4. Radio-active iodine.
5. Oxytocin.
6. GNRH analogues.
7. Diloxanate furate.
8. Bromocryptine.
9. Vinca alkaloids.
10. Folinic acid.

*******
[KX 545] AUGUST 2010 Sub. Code : 4066

SECOND M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations
Paper VI – PHARMACOLOGY – II
Q. P. Code : 524066
Time : Three hours Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Essay Questions : (2 x 15 = 30)
1. i) Enumerate the antimetabolites used in neoplastic diseases.
ii) Write the mechanism of action and therapeutic uses of Methotrexate.
iii) Add a note on treatment of Methotrexate toxicity.
2. i) Classify antithyroid agents.
ii) Mention the pharmacological actions and therapeutic uses of carbimazole.
iii) Add a note on radioactive iodine.

II. Write Short notes on : (10 x 5 = 50)

1. INH.
2. Management of cerebral malaria.
3. Ketoconazole.
4. Treatment of scabies.
5. Management of diabetic ketoacidosis.
6. Selective Estrogen Receptor Modulators (SERMS).
7. Newer insulin preparations.
8. Low molecular weight heparins.
9. Vitamin – D.
10. British Anti-Lewisite (BAL).

III. Short Answer Questions : (10 x 2 = 20)

1. Rationale for giving chloroquine and primaquine in acute vivax malaria.
2. Rationale for using clofazimine in lepra reaction.
3. Two Uses and Two adverse effects of metronidazole.
4. Why ciprofloxacin is contraindicated in children less than 8 yrs of age?
5. Two indications of albendazole.
6. Sulfonylureas are not effective in Type I diabetes mellitus.
7. What is grey baby syndrome?
8. Rationale for using Bromocriptine in acromegaly.
9. Ranitidine is preferred to cimetidine in peptic ulcer.
10. Cisplatin.

*******
[KY 545] FEBRUARY 2011 Sub. Code : 4066

SECOND M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations
Paper VI – PHARMACOLOGY – II
Q. P. Code : 524066
Time : Three hours Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Essay Questions : (2 x 15 = 30)
1. i) Enumerate Anti Tubercular Drugs.
ii) Write the Mechanism of Action and Adverse effects of any one standard drug.
iii) Write briefly on short course chemotherapy.
2. i) Classify Glucocorticoids.
ii) Mention Pharmacological actions of Glucocorticoids.
iii) Enumerate adverse effects and uses of Glucocorticoids.

II. Write Short notes on : (10 x 5 = 50)

1. Adverse effects and uses of Metronidazole.
2. Anticancer antibiotics.
3. Clarithromycin.
4. Insulin Resistance.
5. Therapeutic uses of oxygen.
6. Bisacodyl.
7. Adverse effects of oral contraceptive pills.
8. Ketoconazole.
9. Iver mectin.
10. Bacterial drug resistance.

III. Short Answer Questions : (10 x 2 = 20)

1. Mention two Injectable contraceptives.
2. Mention two Betalactamase inhibitors and their uses.
3. Name two drugs used in Anerobic Infections.
4. Mention four Non malarial uses of chloroquine.
5. Name two Topical & two systemic drugs used in Psoriasis.
6. Write the mechanism of action and uses of Dimercaprol.
7. Mention two differences between oxytocin and Ergometrine.
8. Rationale in the use of Cotrimoxazole.
9. Mention two Monoclonal antibodies and their uses.
10. Justify the preference of Ranitidine over Cimetidine.

*******
[KZ 545] AUGUST 2011 Sub. Code : 4066

SECOND M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations
Paper VI – PHARMACOLOGY – II
Q. P. Code : 524066
Time : Three hours Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Essay Questions : (2 x 15 = 30)
1. i) What are the various methods of hormonal contraception?
ii) Discuss the mechanism of action of hormonal contraceptives.
iii) Mention the complications of contraceptive use.
2. i) Classify Antiamoebic drugs.
ii) Discuss the adverse effects and indications of Nitroimidazoles used in Amoebiasis.
iii) Write briefly on Nitazoxanide.
II. Write Short notes on : (10 x 5 = 50)
1. Pyrazinamide.
2. Drugs used in TYPHOID fever.
3. Insulin resistance.
4. Diethylcarbamazine citrate.
5. Methotrexate.
6. Prednisolone.
7. Propylthiouracil.
8. Ranitidine.
9. Raloxifene.
10. Pyrimethamine.

III. Short Answer questions : (10 x 2 = 20)

1. Mention two calcineurin inhibitors. Mention two uses.
2. What is Cisplatin? Mention two uses.
3. Name two conditions where multi drug therapy is indicated with antimicrobials.
4. Mention two examples each for bacteriostatic and bactericidal drugs.
5. What is the mechanism of action of Vinca alkaloids?
6. Which antithyroid drug inhibits hormone release from thyroid? Mention two uses.
7. Mention two insulin analogues.
8. Mention two Antioestrogens. Mention two indications.
9. Mention two conditions requiring Hormone replacement therapy.
What hormones are given?
10. Name the Mast cell stabilizers. What is their role in Bronchial asthma?

*******
[LB 545] AUGUST 2012 Sub. Code : 4066

SECOND M.B.B.S. DEGREE EXAMINATION

Paper II – PHARMACOLOGY – II
Q. P. Code : 524066
Time : 180 Minutes Maximum: 40 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Elaborate on: Pages Time Marks
(Max.) (Max.) (Max.)
1. a. Classify the drugs used for the treatment of fungal infections.
b. Explain the mechanism of action, interactions, adverse
effects and uses of Ketoconazole. 16 30 10

2. Discuss the pharmacotherapy of Helicobacter pylori infection. 8 20 5

II. Write notes on:

1. Meropenem. 3 8 1.5
2. Adverse effects and uses of lodides. 3 8 1.5
3. Erythrocytic schizontocidal agents. 3 8 1.5
4. Enumerate the serious complications of oral contraceptives. 3 8 1.5
5. Indications for oral hypoglycemic agents. 3 8 1.5
6. Management of functional constipation. 3 8 1.5
7. Gentamicin – PMMA (Polymethyl methacrylate) chain. 3 8 1.5
8. Management of multi drug resistant Tuberculosis (MDR-TB). 3 8 1.5
9. Clofazimine in Leprosy. 3 8 1.5
10. Fusion inhibitors in HIV infection. 3 8 1.5

III. Short Answers on:

1. Mechanism of action of Cephalosporins. 2 5 1
2. Post antibiotic effect. 2 5 1
3. Cinacalcet. 2 5 1
4. Name two highly selective corticosteroids and give their 2 uses. 2 5 1
5. Precautions for use of tetracyclines. 2 5 1
6. Special pharmacokinetic properties of Azithromycin. 2 5 1
7. Mechanism of action of Paclitaxel. 2 5 1
8. What is Mycophenolate Mofetil and explain its mechanism
of action. 2 5 1
9. Name four antiseborrheics. 2 5 1
10. Ondansetron as an antiemetic. 2 5 1

*******
[LC 545] FEBRUARY 2013 Sub. Code : 4066

SECOND M.B.B.S. DEGREE EXAMINATION

Paper II – PHARMACOLOGY – II
Q. P. Code : 524066
Time: Three Hours Maximum: 100 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Elaborate on: (2 x 15 = 30)
1. a. Classify Anti Thyroid drugs.
b. Adverse effects and uses of propylthiouracil.
c. Treatment of thyroid storm.
2. a. Classify fluroquinolones.
b. Explain the mechanism of action and uses of second generation fluroquinolones.

II. Write notes on : (10 x 5 = 50)

1. Centrally acting muscle relaxants.
2. Complication of spinal anaesthesia.
3. Biological Response modifiers.
4. Therapeutic uses of Vitamin A.
5. Newer Macrolides.
6. Post Exposure prophylaxis of Rabies.
7. Dimercaprol.
8. Streptokinase.
9. Drugs for psoriasis.
10. Treatment of Bellodona poisoning.

III. Short Answers on: (10 x 2 = 20)

1. Semi synthetic Penicillin.
2. Imipenem.
3. Name four Topical Anti fungals.
4. Injectable contraceptives.
5. Adverse effects of Aminoglycoside Antibiotics.
6. Oxytocin Antagonist.
7. Uses of Methotrexate.
8. Treatment of lepra reaction.
9. Enfuvirtide.
10. Intra vaginal preparations for Trchomonas Vaginalis.

*******
[LD 545] AUGUST 2013 Sub. Code : 4066

SECOND M.B.B.S. DEGREE EXAMINATION

Paper II – PHARMACOLOGY – II
Q. P. Code : 524066
Time: Three Hours Maximum: 40 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Elaborate on: (2 x 7.5 = 15)
1. a. Enumerate and discuss the pharmacology of newer insulin analogues.
b. Add a note on insulin resistance.
2. Discuss the mechanism of action, Spectrum of activity and uses of Metronidazole.

II. Write Notes on: (10 x 1.5 = 15)

1. PUVA (Psoralen Ultra Violet A).
2. Explain the mechanism of action & uses of Calcineurin inhibitors.
3. Bleomycin.
4. Tegaserod.
5. Pharmacotherapy of Gastro Esophageal Reflex Disease.
6. Zoledronate.
7. Emergency Contraception.
8. Gatifloxacin.
9. Name 2 Superactive GnRH agonist & what are their uses.
10. Role of corticosteroids in Tuberculosis management.

III. Short Answers on: (10 x 1 = 10)

1. Advantages of Artemisinin based Combination Therapy (ACT).
2. Albendazole in Neurocysticercosis.
3. Oseltamivir.
4. Management of Lepra reaction.
5. Sulfasalazine as an antidiarrhoeal agent.
6. Atosiban.
7. Drugs used for Thyrotoxic crisis.
8. Chemoprophylaxis.
9. Ototoxicity produced by Aminoglycosides.
10. Vancomycin.

*******
[LE 545] FEBRUARY 2014 Sub. Code: 4066

SECOND YEAR MBBS DEGREE EXAMINATION

Paper II – PHARMACOLOGY – II
Q. P. Code: 524066
Time: Three Hours Maximum: 40 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Elaborate on: (2 x 7.5 = 15)
1. a. Classify the drugs used for Diabetes Mellitus.
b. Discuss the actions and the available preparations of insulin.
2. a. Classify the drugs used for the treatment of peptic ulcer.
b. Discuss the mechanism of action and uses of proton pump inhibitors.

II. Write Notes on: (10 x 1.5 = 15)

1. Plasma expanders
2. Drugs for Gastroesophageal reflux disease
3. Rifampin
4. Classification of anti cancer drugs.
5. Metformin
6. Therapeutic uses and adverse effects of Gonadotropins.
7. Artemisinin based combination therapy.
8. Albendazole.
9. Sitagliptin
10. Fourth generation cephalosporins

III. Short Answers on: (10 x 1 = 10)

1. Mention four anticoagulants used in vitro.
2. Mention four therapeutic uses of vitamin D.
3. Give four examples of Fluroquinolones.
4. Mention four antiretroviral drugs
5. Mention four antimalarial drugs
6. Mention four contraindication for heparin.
7. Mention four HMG-COA reductase inhibitors.
8. Mention four antiamoebic drugs.
9. Mention four first line Anti tubercular agents.
10. Mention four topical antifungal drugs

*******
[LF 544] AUGUST 2014 Sub. Code: 4066

SECOND YEAR M.B.B.S DEGREE EXAMINATION

Paper II – PHARMACOLOGY - II
Q. P. Code: 524066
Time: Three Hours Maximum: 40 Marks
Answer ALL questions in the same order.
I. Elaborate on: (2 x 7.5 = 15)
1. Classify immunosuppressants.
Describe the mechanism of action, adverse effects and therapeutic uses of
calcineurin inhibitors.
2. Classify antimalarial drugs.
Describe in detail about Chloroquine resistance Malaria treatment.
II. Write Notes on: (10 x 1.5 = 15)
1. Prophylaxis of HIV infection
2. Menopausal hormone replacement therapy
3. Human insulins
4. Sulfasalazine
5. 5HT3 antagonists
6. Antipseudomonal penicillins
7. 5 alpha reductase inhibitors
8. Radioactive iodine
9. Treatment of acne vulgaris
10. Short course chemotherapy in tuberculosis.

III. Short Answers on: (10 x 1 = 10)

1. Mechanism of action of ciprofloxacin
2. Sulfone syndrome
3. Enumerate the differences between propyl thiouracil and carbimazole
4. Emergency contraception
5. Citrovorum factor rescue
6. Enumerate the contraindications of steroids
7. Super ORS
8. Mechanism of action of omeprazole
9. Write the mechanism of action and uses of Ivermectin
10. Newer formulations of Amphotericin B.

.*******
[LG 544] FEBRUARY 2015 Sub.Code :4066

M.B.B.S. DEGREE EXAMINATION

SECOND YEAR
PAPER II – PHARMACOLOGY II

Q.P. Code: 524066

Time: Three hours Maximum : 40 Marks
Answer All Questions
I. Elaborate on: (1 x 10 = 10)

1. Classify the drugs used for the treatment of fungal infections. Explain the
mechanism of action, drug interactions, adverse effects and therapeutic uses of
Griseofulvin.

II. Write notes on: (4 x 5 = 20)

1. Low molecular weight heparin

2. British Anti lewisite
3. Drug regimen in H. Pylori
4. Lepra reaction

III. Short answers on: (5 x 2 = 10)

1. Why imipenem is administered with cilastatin?

2. Mebendazole
3. Adverse effects of Aminoglycosides
4. Therapeutic uses of Metronidazole
5. Mechanism of action of Sulfonylureas

********
[LH 545] AUGUST 2015 Sub. Code: 4066

SECOND M.B.B.S. DEGREE EXAMINATION

PAPER II – PHARMACOLOGY - II
Q.P. Code: 524066
Time : Three Hours Maximum : 40 marks
Answer ALL questions
I. Elaborate: (1 x 10 = 10)
1. Classify Cephalosporins.
Discuss the mechanism of action, uses and adverse effects of Cephalosporins.
Write briefly about postantibiotic effect.

II. Write notes on : (4 x 5 = 20)

1. Methotrexate.

2. Cotrimoxazole.

3. Clinical uses of Somatostatin and Octreotide.

4. Classify antiemetic agents.

III. Short answers on : (5 x 2 = 10)

1. Name four microtubule damaging agents used for chemotherapy for cancer.

2. Danazol.

3. Artemisinin derivatives in Malaria.

4. Ezetimibe.

5. Thrombolytic drugs.

*******
[LI 545] FEBRUARY 2016 Sub. Code: 4066

SECOND YEAR M.B.B.S. DEGREE EXAMINATION

PAPER II – PHARMACOLOGY - II
Q.P. Code : 524066
Time : Three Hours Maximum : 40 Marks
Answer ALL questions
I. Elaborate on: (1 x 10 = 10)
1. a) Classify Beta lactam antibiotics.

b) Mention the mechanism of action, adverse effects and uses of Penicillins.

c) Write briefly about Beta-lactamase inhibitors.

II. Write notes on: (4 x 5 = 20)

1. Paclitaxel.

2. Domperidone.

3. Erythropoetin.

4. Statins.

III. Short answers on: (5 x 2 = 10)

1. Mention four drugs for Scabies.

2. Mention the toxicities of quinolones.

3. Mention four oral hypoglycemic drugs. Mention their mechanisms of action.

4. Mention four uses of thyroid hormone.

5. Antimotility drugs.

*******
[LJ 545] AUGUST 2016 Sub. Code : 4066

SECOND YEAR M.B.B.S. DEGREE EXAMINATION

PAPER II – PHARMACOLOGY - II
Q. P. Code : 524066
Time : Three hours Maximum: 40 Marks
Answer ALL questions.
I. Elaborate on : (1 x 10 = 10)
1. Classify the drugs used for tuberculosis.
Discuss the mechanism of action, pharmacokinetics and adverse effects of isoniazid.

II. Write notes on: (4 x 5 = 20)

1. Vinca alkaloids.

2. Oxytocin.

3. Bulk purgatives.

4. Prokinetic drugs.

III. Short answers on: (5 x 2 = 10)

1. Hepatitis B vaccine.

2. Vitamin K.

3. Mechanism of action of Cotrimoxazole.

4. Mention four uses of corticosteroids.

5. Mention four factors affecting the absorption of iron.

*******
[LK 544] FEBRUARY 2017 Sub.Code :5062

M.B.B.S. DEGREE EXAMINATION

SECOND YEAR
PAPER II – PHARMACOLOGY II

Q.P. Code: 525062

Time: Three hours Maximum : 40 Marks
Answer All Questions
I. Elaborate on: (1 x 10 = 10)

1. Classify drugs used in peptic ulcer. Discuss the mechanism of action, uses and
adverse effects of proton pump inhibitors.

II. Write notes on: (4 x 5 = 20)

1. Mechanism of action, uses and adverse effects of methotrexate.

2. Enumerate insulin analogs. Write their indications and advantages.
3. Mechanism of action, uses and adverse effects of metronidazole.
4. Bisphosphonates. 

III. Short answers on: (5 x 2 = 10)

1. Mention four drugs used for acne.

2. Write two adverse effects and two contraindications of corticosteroids.
3. Mention one use of fluconazole and write the advantage of fluconazole
over ketoconazole.
4. Write four general toxicities of cytotoxic drugs.
5. Write four adverse effects of oral contraceptive pills. 

********
 [LL 544] AUGUST 2017 Sub.Code :5062

M.B.B.S. DEGREE EXAMINATION

SECOND YEAR
PAPER II – PHARMACOLOGY II

Q.P. Code: 525062

Time: Three hours Maximum : 40 Marks
Answer All Questions
I. Elaborate on: (1 x 10 = 10)

1. Classify drugs used in the treatment of malaria. Outline mechanism of action and
advantages of chloroquine. Write a note on prophylaxis of malaria.

II. Write notes on: (4 x 5 = 20)

1. Treatment of scabies.
2. Triple regimen for H.Pylori infection.
3. Advantages and contraindications of OCP.
4. Mechanism of action and therapeutic uses and adverse effects of lovastatin.

III. Short answers on: (5 x 2 = 10)

1. Two uses and two adverse effects of Vitamin D.

2. Mupirocin.
3. Write four immunosuppressant’s and their uses.
4. Mention four newer oral anti-diabetic drugs.
5. Name two drugs used for filariasis. Mention the mechanism of action of these
drugs.

********