COLOSTRUM

LIFE’S FIRST FOOD

THE
ULTIMATE
ANTI-AGING
WEIGHT LOSS
AND
B^IMMUNE
SUPPLEMENT
COLOSTRUM
LIFE'S FIRST FOOD

THE

ULTIMATE
ANTI-AGING
WEIGHT LOSS
AND

IMMUNE
SUPPLEMENT

DANIEL G. CLARK, MD
AND

KAYE WYATT

CNR PUBLICATIONS™
THE CENTER FOR NUTRITIONAL RESEARCH
 “If we could see beyond today,
as God can see,
The clouds would roll away,
He is our joy,
Our joy in sorrow,
Our hope for tomorrow,
He’ll give you as far as
you can see”.

Unknown Gospel Hymn

First Printing March, 1996; Second Printing July, 1996;

Third Printing February, 1998; Fourth Printing August, 1998.

Copyright © 1996 by CNR Publications.

All rights reserved. No part of this book may be reproduced or transmitted by any
means, electronic or mechanical, without the written permission from the publisher,
except in the case of brief quotations embodied in critical articles and reviews.
For information or letters to the authors address the publisher below:

CNR Publications, LC
4700 South 900 East Suite 30-257
Salt Lake City, Utah 84117
Printed in the United States of America

'Colostrum: Life’s First Food. The Ultimate Anti-Aging, Weight Loss and Immune
Supplement’; is not intended as medical advice. Its intention is solely informational
and educational. It is wise to consult your doctor for any illness or medical condition.

Credits:
Research: Douglas Wyatt, Kaye Wyatt
Various input provided: Kirk Robinson, Ph.D., Barbara Gilson RN, M.S.,
John Hammer DDS, Anthony Smith, M.S., Kimberly Smith B.S.
Editing: Kirk Robinson, Ph.D., Barbara Gilson, RN, M.S., Kimberly Smith, B.S.
Typesetting: CNR Publications
Cover design: EPC Electronic Publishing
Cover Photo: Douglas Wyatt
Art: Art Explosion

CNR Publications is a subsidiary of The Center for Nutritional Research

an independent research organization
WHAT DOCTORS HAVE TO SAY ABOUT
COLOSTRUM
Colostrum has a virus antibody that acts against viral
invaders. A wide range of antiviral factors were acknowledged
to be present in colostrum. This research was done at the US
Government’s Center for Disease Control in Atlanta, Georgia.
Dr. E.L. Palmer, et. al.; Journal of Medical Virology

Colostrum contains Non Specific Inhibitors that inhibit a wide

range of respiratory illness, notably Influenza viruses.
Colostrum is specifically cited for its unique effectiveness
against potentially deadly outbreaks of Asian Flu viruses that
emerge from animal/human mutations.
Drs. Shortridge, et.al.; Journal of Tropical Pediatrics

Glycoproteins, in bovine colostrum, inhibit the attachment of

the Helicobactor Pylori bacteria that cause stomach ulcers.
Colostrum contains significant amounts of lnterlukin-10
(a strong inflammation inhibitory agent), found significant in
reducing inflammation in arthritic joints and injury areas.
Dr. Olle Hernell, At the University of Ulmea, Sweden; Science

Colostrum and breast milk (from cows and humans)

stimulates the newborn’s immune system; as yet, unidentified
proteins speed the maturation of cultured B Lymphocytes
(type of white blood cell) and primes them for production of
antibodies.
Dr. Michael Julius Of McGill University, Montreal; Science News

Immunoglobulins (found in colostrum) are able to neutralize

the most harmful bacteria, viruses, and yeasts.
Dr. Per Brandtzaeg; Annals of the New York Academy of Sciences

Human clinical study: Immune factors in cow colostrum, when

taken orally, are effective against disease-causing organisms
in the intestinal tract. Ingestion of bovine colostrum’s
immunoglobulins may be a new method of providing passive
immunoprotection against a host of gut-associated disease
causing antigens (viral and bacterial).
Dr. R. McClead, et. al.; Pediatrics Research
Clinical studies show that IgE (Immunoglobulin), found in
bovine colostrum, may be responsible for regulating allergic
response.
Drs. Tortora, Funke & Cast; Microbiology

Studies with human volunteers found that the preservation of

the biological activity of IgG (Immunoglobulin), in the
digestive secretions of adults receiving bovine colostrum
orally, indicates passive enteral (intestinal) immunization for
the prevention and treatment of acute intestinal diseases.
Dr. L.B. Khazenson; Microbial & Epidemial Immunobiology

Colostrum stimulates the lymphoid tissue providing benefits

in aged or immunodeficient people. Nature has used the oral
route for the development of the immune system since the
origin of mammals (safe and effective). Oral administration of
immunofactors is simple, inexpensive, free of side effects and
may be vastly beneficial in veterinary and HUMAN medicine, to
correct immunodeficiency.
Drs. Bocci, Bremen, Corradeschi, Luzzi and Paulesu; Journal
Biology

Immunoglobulin from bovine colostrum effectively reduces

and prevents viral and bacterial infections in immune deficient
subjects: bone marrow recipients, premature babies, AIDS,
etc.
New England Journal of Medicine

Researchers reported that colostrum stimulates maturation of

B Lymphocytes (type of white blood cell) and primes them for
production of antibodies, enhances growth and differentiation
of white blood cells. Similar activity in cow and human
colostrum can also activate Macrophages.
Dr. M. Julius, McGill University, Montreal; Science News

Immunoglobulin in colostrum has been used to successfully

treat: Thrombocytopenia, Anemia, Neutropenia, Myasthenia
Gravis, Guillain Barre Syndrome, Multiple Sclerosis, Systemic
Lupus, Rheumatoid Arthritis, Bulluos Pamphigoid, Kawasaki’s
Syndrome, Chronic Fatigue Syndrome and Crohn’s disease,
among others.
Dr. Dwyer; New England Journal of Medicine
Concentration of Lactoferrin and Transferrin in bovine
colostrum found necessary to transport iron into blood.
Highest concentrations of both substances were found in the
first milking after birth.
Drs. Sanchez, et al, Biological Chemistry

PRP, in bovine colostrum, has the same ability to regulate

activity of the immune system as hormones of the Thymus
gland. It activates an underactive immune system, helping it
move into action against disease-causing organisms. PRP
also suppresses an overactive immune system, such as is
often seen in the autoimmune diseases. PRP is highly anti­
inflammatory and also appears to act on T-cell precursors to
produce helper T-cells and suppresser T-cells.
Drs. Staroscik, et. al., Molecular Immunology

PRP was found not to be species specific (transferable for

human use). Turns white blood cells into functionally active T
cells. Results were shown in treatment of auto-immune
disorders and cancer. An important Immune modulator
stimulates an underactive immune system and tones down an
overactive one.
Drs. Janusz & Lisowski; Archives of Immunology

Bovine Colostrum contains TgF-B which has an important

suppressive effect on cytoxic substances (anti-inflammatory).
Inhibits cell growth of human Osteosarcoma (cancer) cells
(75% inhibition). Mediator of fibrosis and angiogenesis
(healing of heart muscle and blood vessels), ( Roberts et al.,
1986), accelerates wound healing (Sporn et al.., 1983) and
bone formation (Centrella et al., 1987).
Drs. Tokuyama and Tokuyama; Cancer Research Inst. Kanazawa
Univ. Japan

Only Retinoic acids, found in colostrum, conferred protection

and reduced colonization of the Herpes Virus. Although not a
cure, Retinoic acids effectively reduce the Herpes Virus to
levels (1/100 to 1/10,000 viruses remained active after
treatment) where the body’s immune system could fight off an
outbreak.
Drs. Charles Isaacs, et. al.; Experimental Biology; Science
Colostrum contains Retinoic Acid which helps fight Herpes
Virus. Also contains Glycoprotein (kappa casein) that protects
against the bacteria that cause stomach ulcers.
Dr. Raloff, Science News

Reducing viral levels in the body and stimulating natural

immune capabilities holds the most promise in helping our
immune systems contain the HIV virus.
Drs. Nowa and McMichael; Scientific American

Growth factors in bovine colostrum were found to be very

effective in promoting wound healing. Recommended for
trauma and surgical healing. External and internal
applications.
Drs. Sporn, et. al.; Science

Cartilage Inducing Factor-A, found in colostrum, stimulates

cartilage repair.
Drs. Seyedin, Thompson, Bentz, et. al.; Journal of Biological
Chemistry

Bovine colostrum contains high levels of growth factors that

promote normal cell growth and DNA synthesis.
Drs. Oda, Shinnichi, et. al.; Comparative Biochemical Physiology

IGF-1, found in colostrum, stimulates bone and muscle growth

and nerve regeneration. Also found: topical administration to
wounds resulted in more effective healing.
Drs. Skottner, Arrhenius-Nyberg, Kanje and Fryklund, Acta.
Paediatric Scandinavia, Sweden

The failure of chronic wounds to heal is a major medical

problem. Drs. suggest that an important role for growth
factors is in promoting wound healing. Accelerated healing is
possible for treatment with trauma and surgical wounds.
Drs. Bhora, et. al.; Journal. Surg. Res.

High age is associated with reduced levels of growth

hormones: GH and lgF-1. Induction of GH and lgF-1 increase
body weight through muscle growth of aged subjects
Drs. Ullman, Sommerland & Skottner, Dept, of Pathology and
Pharmacology, Univ. of Gothenburg, Sahlgren Hospital &
HabiVitrum AB, Stockholm, Sweden
 TABLE OF CONTENTS

Introduction (Super Bugs are Coming)....................................1

He’ll Give You as Far as You Can See............... .....................3

Colostrum’s Healing Power: Daniel G. Clark, M.D.

Chapter One
Life Supporting Colostrum.................................................... 11

Chapter Two
Conditions that Allow Disease to Develop...........................17

Chapter Three
The Immune Response...........................................................23

Chapter Four
Components of Colostrum.....................................................27

Chapter Five
Colostrum and Disease........................................................... 33

Chapter Six
Healing, Weight Loss and Athletic Endurance......................43

Chapter Seven
Fountian of Youth.................................................................... 49

Effective Use............................................................................ 51

Conclusion............................................................................... 53

Testimonials............................................................................. 55

Bibliography. 59
INTRODUCTION

SUPER-BUGS
ARE
COMING !
We read about it on the front page of the newspaper or hear about
it on the evening news. The movie industry has capitalized on the
theme for the latest terror movies. SUPER BUGS ARE COMING
and they can’t be stopped. So far, this has not become real for us.
We need to pay attention and take responsibility for ourselves
NOW if we are going to survive.

The number one killer in the world today is immune

disease. It is now understood that all disease is immune related.
Immune deficiencies, autoimmune diseases, heart disease,
cancer, allergies, infections, diabetes, ulcers, even aging are
immune related. The onset and progressive development of
disease is the result of a weakened or overactive immune system.
Toxic accumulations in the body’s tissues and nutritional
deficiencies destroy the immune system. Unfortunately, healthy life
choices that protect our immune systems have been admittedly
elusive goals for many of us.

When our body systems break down and we get sick, we

automatically look to a drug to make us better. Drugs are useful for
life-saving emergencies or when other more natural methods have
been exhausted. We need to understand how our immune system
works, when drugs are called for and the sometimes dangerous
and irreversible side effects that drugs can produce in our body.
Antibiotic drugs can combat most bacterial illness but can’t harm a
single known virus. With antibiotic use, we have encouraged the
growth of yeast throughout the body and along with sulfa and
antihistamines, impaired our digestive systems’ ability to process
nutrients and eliminate toxins and pathogens. Drugs are capable
of combining with previously existing drug residues, chemicals and
heavy metals already in our bowel and body tissues, producing
extremely toxic effects and carcinogens. Lately, we’ve been
hearing that there is a growing list of bacteria and microbes that
have mutated and become resistant to antibiotics. What drug can
we depend on now?
1
 Many of us feel that we have taken a giant step toward
upgrading our health with natural preventative medicines. We self-
diagnose and prescribe based on the latest advice from would-be
“experts" without investigating the research or the credibility of the
research behind the claims. Isolating and megadosing on single
micro-nutrients or randomly combining them can upset our
homeostatic balance, creating dangerous conditions within our
body.

We have changed the face of our planet in just a few

generations. Food, our fuel for life, has been chemically altered
and laced with pollutants and antibiotics. Our nation is showing
evidence of malnutrition from nutrient-poor food due to erosion
losses and mineral depletion of its' topsoil. We have polluted our
precious air and water. We are dealing with environmental
chemicals, devices that produce stray electromagnetic fields and
social neglect. We are now becoming aware of how our destruction
of the rain forest has introduced viruses and bacteria that our
species has never had to contend with. What can we do to save
ourselves?
When we combine a weakened immune response,
inexpensive world travel and super bugs, we have a crisis in the
making that the world has yet to behold. How can we stop this
planetary nightmare?
Hold onto your seats and get ready for an eye opening
experience into the truth surrounding a product some have called
the discovery of our time - a rediscovery actually - COLOSTRUM,
Life’s First Food. Colostrum has been used successfully
throughout history by numerous cultures in the world. We invite
you to investigate the research by some of the most famous
universities and medical clinics in the world, evidencing
colostrum’s unprecedented immune and tissue repair benefits.

2
HE’LL GIVE YOU
AS FAR
AS YOU CAN SEE
BY KAYE WYATT

This evening, Mother Nature was about to

give one of her finest performances. As she
calmed the breeze, she gave all of summer’s
wondrous smells, sounds and sights center
stage - the fragrance of catalpa blossoms,
duck’s laughter and one of Salt Lake City’s
spectacular sunsets. Sitting next to my husband on our deck that
overlooks the valley, I realized that even after all these years, he
still had the power to make my heart skip a beat. The peace and
euphoria became intoxicating as we waited for the show to begin.
The sun had slipped behind the clouds in it's reach for the western
mountains. Pirate ships, illuminated in gold, took form in the clouds
as the slanting rays went into hiding. Their massive sails looked
innocent in shades of pink but suddenly graduated to fiery red
against the turquoise sea. Pirate ships - pirates - were they coming
for me? Quickly, I closed my eyes, willing these menacing images
to disappear. I allowed my mind to wander to the special people
who touch my thoughts daily ... a mother I adore, a supportive
brother and sister, three almost perfect children and five perfect
grandchildren.

It seems that my husband, Doug, and I have always had

the ability to know what the other was thinking at any given
moment, so it was no surprise that when my tears came, I saw
them mirrored in my husband. I've been accused of living in a
happy ever after world instead of the real world. I know that our
expectations create our reality. I’ve always held onto the belief that
any problem I encounter in life will eventually work out for the best,
no matter how hopeless it appears. This belief has become my
reality. This evening, with hope quickly dissipating, my beliefs were
being challenged. My immune system was losing it’s fight against
continual bacterial and viral infections - I was dying - there would
be no happy ever after for us.

3
 My entrance into this world set the precedent for how
I would approach every problem in my life - hit it head on and get it
behind you. My mother barely made it to the hospital in time. My
parents were thrilled that they had a boy first and that now they
had a little girl. Their elation was shattered after they brought me
home from the hospital and it seemed like I almost became allergic
to this world. During that first month of my life, my breathing
became increasingly more erratic and labored and they realized
that I was in serious trouble. There was no sleep for my mother, as
she lay by my side clutching my hand. It took only one time for me
to stop breathing altogether and turn blue, to make them insist on
an answer from the doctor. I think that I was born during the dark
ages of medicine because treatment for respiratory distress at that
time was heavy radiation of the thymus gland. I can’t imagine that
they didn’t know that the thymus gland is the master control of the
immune system.

As the years progressed, so did my allergies. I was very

allergic to cow’s milk, so my parents had to drive long distances to
farms for goat’s milk. To make sure that they could get enough to
last a couple of days, they had to get up at the crack of dawn and
find it before everyone else did. Despite all of my parents efforts to
keep me away from known allergens, I was continually struggling
with asthma, hives and eczema. I can vividly recall vacations that I
should have been too young to remember because of my serious
asthma attacks. My memory is of the bathrooms in motels - the
feeling of panic reinforced from my parent’s anxiety - waiting for
the steam from the shower to give me my breath back. I don't know
how I learned that these attacks weren’t as bad if I relaxed and
didn’t panic. When I was older, they were able to control the
severity of my asthma attacks with drugs and cortisone shots. The
stage had now been set for the fight of my life - a fight for survival
- equipped with a radiation weakened immune system and drugs
that proved to be deadly boomerangs.

After the birth of my third child, my asthma seemed to

lessen but bacterial and viral infections in my bronchioles and
lungs took it's place. I was teaching at the junior high school.
Between the germs that my children brought home and the germs
that I picked up at school, I remember taking an antibiotic almost
every month. When I think back on that time of my life, I should
have at least questioned why my body was having more difficulty
with illness and healing than other people. When I was twenty
five, I had a partial hysterectomy and should have recovered fully
4
within a month’s time. Three weeks after the hysterectomy, I was
still in the hospital with infection and recurring hemorrhaging. I
came home looking like a skeleton and it took months, with my
mother’s help, to get me back on my feet. A couple of years after
that, I had all four wisdom teeth removed in two sessions. I
remember my dentist telling me how rare it was for a person to
have a dry socket, so I needn’t worry. Both teeth removed in the
first session left dry sockets that took months to heal. I remember
the pain being unbearable. He assured me that it couldn’t happen
again. With me it could and it did.

About ten years ago, I had finally reached the point where
I was unable to work because of constant dental surgeries and
associated infections. Of course, more antibiotics were called for.
Root canal surgeries could not be done the traditional way. They
had to go through the gums because my roots had calcified. My
dentist said he thought that this was caused from an allergy to the
metals that were used or prior trauma to the teeth from extensive
work. Is it possible that it had something to do with my body’s
inability to heal? It was right after that, that as much as I needed to
work and as much as I wanted to work, I couldn’t. I would last only
a couple of hours each morning before my temperature would soar
and I would collapse in bed. The nuisance of accompanying fever
blisters was unending. About this time, because I needed two or
three antibiotics in a row to control an infection, Doug told me that
there would be no more antibiotics. His mother had been using
Herbs to heal since he was a child. I would, from this day forward,
use natural antibiotics (Echinacea and Goldenseal) that didn’t
destroy the body.

Life was very difficult from that point on for both

i> * v Doug and me. We could never plan ahead to do
•"'ft anything - a vacation, a day’s adventure or even
an evening out. Eventually, I would get so angry
with myself and force myself to go out for a day or
kp-. an evening with my husband. Within a very short
time, my rising fever would forbid any enjoyment for me with
demanding thoughts of wanting to be home in bed. Sometimes
I think that there was only one bug that lived in my body for those
ten years. I needed to take at least one antibiotic each year for
pneumonia but I don’t think it killed him. He couldn’t have found a
safer home. I don’t remember, even one day, not feeling sick.

5
 During those years, Doug and I investigated everything
that might possibly lead to my healing. I enrolled in several
nutrition classes at the university and he bought health-related
cookbooks (his hobby is cooking). Every week, we would visit the
library and end up bringing home stacks of books. We found the
mind-body connection to be the most promising. I had the honor of
working with one of the finest hypnotherapists, known throughout
the world, Ormond McGill. I feel that this work made it possible for
me to survive until I found colostrum. And of course, like so many
people, we wasted a lot of time and money on miracle cures. This
was the reason that I refused to pay attention to colostrum when
my husband first brought it home. I felt that anything that made so
many promises would again prove to be too good to be true.

As the sunset’s brilliance gave way to shades of gray, with

tears in place of words, Doug took my hand and asked me not to
give up hope. A couple of days later, he brought home a jar of
bovine colostrum that he had purchased from a naturopathic
doctor for $160. He was so excited as he told me about the
immune and growth factors in colostrum. I felt that this was money
we could not afford to spend, especially on another
disappointment. I told him the last thing that I needed right now
was growth factors to make my feet grow bigger (they don't do that,
of course). It was only a couple of days later that I fell and
seriously injured my knee. I was hemorrhaging into the kneecap.
We immediately went to the emergency room where they put my
leg in a Velcro cast. They told me to stay off it and keep it elevated
for a couple of weeks. When I got home, I was trembling with pain
and told Doug, 'Okay, I’m ready to take your medicine’ (that’s not
quite how I said it). I took a heaping tablespoonful with some
water. I couldn’t sleep with the cast on, so Doug helped me take it
off. The next morning, Doug was the first one up, reading the
newspaper when I came in. I was pouring myself some juice, when
he looked at me funny and kept repeating my name. It took a
moment before I realized that I was standing pain free on a leg that
I couldn’t put any weight on the evening before. I pulled up my
nightgown and looked at a knee that showed no indication that
anything had ever happened to it.

This was the beginning of a new life for me. It was a

couple of days later that I broke my temperature for the last time!
Also, no more fever blisters. There were so many changes in my
body, which I discovered after the fact, from research articles, that
were attributable to the colostrum. I noticed that my toenails were
6
growing in pink, flat and healthy. Before colostrum, the doctor was
considering removing them because of an advanced fungus which
was a result of years of antibiotic use.

Two years ago, my doctor tested me for Serotonin

(neurotransmitter) uptake because I was having episodes of
severe depression. He told me that my tests were the worst he’d
ever seen. He said that people in my condition were known, in a
split second, to drive off a cliff. I didn’t realize that I was that bad.
The antidepressants prescribed for me created frightening side
effects and did not help. When I started taking colostrum, I had no
idea that it could help with depression. Within a very short time, I
felt like a weight had been removed - life was beautiful and
meaningful! I had to find out if it was the colostrum so I purposely
stopped taking it for a couple of days. There was no mistake. Each
morning, I would wake up with the best of intentions to really
accomplish a lot that day. My good intentions and the energy to
carry them through fizzled before I even began. My thinking wasn’t
as clear and according to one of my friends, I wasn’t my happy
self. She told me after talking to me on the telephone for a few
minutes, “you’ve stopped taking your colostrum, haven’t you”.

I had another pleasant surprise. The Naturopathic Docto

that introduced us to colostrum, told me that it might help my
gingivitis. My dentist felt that I might have to consider gum surgery,
it was so advanced (very sensitive teeth and sore and bleeding
gums). I faithfully packed my gums with powdered colostrum every
evening for a couple of weeks. That’s all it took. On my next visit,
my dentist couldn’t believe that I showed no signs of gingivitis.
He’s recommending colostrum to all of his patients.

Recently, after reading some new research reports on the

critical importance of bowel health (something that we won't even
talk about to ourselves), I realized how seriously ill I was before
colostrum. I feel that this is the area that people will notice a
difference immediately and will be the most beneficial for their
health.

In my excitement, I wanted everyone to have a new

chance at life with colostrum. It was several months before I
remembered something I’ve known for a long time. There are a lot
of people that really want to be sick. Sickness has always had an
element of control and escapism in it. As a child, we were coddled
by our mothers whenever we ran a fever and seriously ill adults are

7
still given intensive care. I’ve witnessed people who hold the belief
that suffering is meaningful and inevitable, even a grace. These
emotions, beliefs and expectations that are connected to illness
are usually established in early childhood. They are so deeply
embedded in the subconscious mind that they probably won’t be
changed or even recognized in this lifetime.

For example, one lady, who suffers from a crippling

disease that the doctors have not been able to put a name to, has
her husband’s complete undivided attention. Most of their time is
spent traveling to exotic places around the world, seeking a cure. I
was distressed to hear how sick she was and so I gave her some
research information and free samples of colostrum. She returned
the samples a week later explaining that this wasn’t the right time
for her to start the colostrum. She told me that she was under a lot
of stress with the holidays coming up and felt that she might be
coming down with the flu. She said that she really thought it would
be best to wait until she felt better before she started taking the
colostrum.

A word of warning: If you take colostrum, you might never

get sympathy again. Doug went out of town on business for a
couple of days. I tripped on a chair leg and either broke or
seriously sprained my big toe. It swelled and turned purple clear up
to my ankle. My neighbor, a nurse, looked at my foot and said that
I probably wouldn't be able to wear a shoe for at least a month.
How was I going to pick up my husband in two days at the airport?
Miraculously, I walked the length of the airport to meet his plane -
no pain, no swelling, no discoloration and no sympathy!

I recently went to visit my daughter in a small town in

Wyoming. I was greeted with hugs and kisses by all of her
husband’s family that I hadn’t seen for quite awhile. I was told a
year ago that if I got pneumonia again, I couldn’t count on
antibiotics to help. Within days, I started getting a little nervous
when everyone suddenly got very sick. They had bad colds and
complained of raw sore throats. One was admitted to the hospital
with bacterial pneumonia. I knew that some of my choices in those
first couple of days of my vacation were not the best for my
immune system. We ate doughnuts for breakfast, went swimming
in the outdoor hot springs pool in freezing temperatures and ate
more of all those good things that you know you shouldn’t eat. This
would certainly be the ultimate test for colostrum. I had been taking
colostrum for almost eight months. A doctor explained to me that

8
sometimes it takes a couple of months for colostrum to strengthen
an immune system as weak as mine. It strengthened mine more
than I ever imagined. My daughter and I got the sniffles for about
an hour one morning and that was it (she also takes colostrum).
That was the first time in my life that my immune system won.

I received an unexpected compliment when I went

swimming with my daughter at the hot springs.
I forgot my bathing suit and had to borrow one from
her (it would have to be a bikini). The cute young
lifeguard at the pool was actually flirting with me. He
asked my daughter if I was her sister.

It’s hard for me to be complimentary about myself but

I have noticed some definite physical changes in my body.
Although I’ve always been slender, ever since I had children, I’ve
carried unwanted weight around my waist. It’s all gone and I’m now
able to wear the same size jeans that I wore in my early twenties.
My muscles are toned with no trace of cellulite and my vericose
veins have disappeared. The only exercise that I’ve had time for in
the last eight months is walking my dog. My hair is finally healthy,
shiny and all the same length which was impossible before with
breakage and split ends. I don’t know if it’s the radiance of health
and feeling on top of the world or the outward physical changes
but everyone who has taken colostrum, for at least a couple of
months, looks shockingly younger. Throughout history, we’ve been
searching for the fountain of youth - 1think the search is over.

I’ve talked with so many people about how colostrum has

dramatically changed their lives. One of my favorite stories is from
a lady who has suffered with crippling arthritis for years. Colostrum
has made it possible for her to walk again and resume the hobbies
she loves, without pain. Several months ago, her veterinarian
recommended that she put the family dog to sleep because he was
showing signs of heart failure. He was listless, barely eating and
his body was bloating. She and her grown children were
distraught. In desperation, she sprinkled colostrum in what little
food he would eat. Within days, he had his appetite back, his
bloating had disappeared and he was playfully acting like a puppy.
She recently shared with us that his coat is shiny again and that he
is so active, he seems to have forgotten his age. But most
important, she said, “He’s always smiling”. Her children were so
shocked at the changes in the dog, they’ve all started taking
colostrum.
9
 Colostrum works. It really works! But remember, each one
of us is unique in regard to age, weight, progression of illness and
lifestyle. We each require more or less of colostrum because it is
not a drug and it’s effects cannot be quantified. I understand that it
has no drug interactions and it is completely safe at any level with
no side effects. I’ve found that my body needs more colostrum than
most people. I take three capsules first thing in the morning on an
empty stomach and again, in the afternoon. You need to work with
your own body and let it tell you what you need. But most of all,
please be patient (although colostrum begins it’s healing and
tissue repair immediately, it may have some work to do).

I want to thank all of the people who have recently put

so much of their time and effort into gathering information,
researching and writing to help bring colostrum to the public’s
awareness. I especially want to thank Dan Clark, MD, for stepping
up and caring enough to write about this remarkable rediscovery.
I hear of so many children and adults today that are suffering from
life-threatening diseases. Dr. Clark has taken us one step closer to
reach out to these people and ask them not to give up hope for a
new life: COLOSTRUM.
COLOSTRUM’S
HEALING POWER
BY DANIEL G. CLARK, MD

CHAPTER ONE
LIFE SUPPORTING COLOSTRUM
When a mother gives birth to her offspring, her mammary
glands provide life supporting factors that she has acquired in her
lifetime. Her body concentrates these factors into a special (non­
milk) immune and growth supporting fluid called colostrum.
A mother produces true colostrum for only the first 24-48 hours
after giving birth. This pre-milk substance is mother natures’
perfect combination of immunoglobulins, specific antibodies and
broad based immune enhancers which protect the newborn
against future viruses, bacteria, allergens and toxins. These
immune factors, along with desirable acidophilus bacteria, “jump
start” immune function in the gut and prevent the development of
gastrointestinal infection. Colostrum also contains a perfect
combination of growth factors that fight disease and infection and
help the newborn grow healthy and heal quickly. It is so important
to newborn animals, that most simply die without it. In humans, as
in animals, it transmits disease immunity and stimulates normal
healthy growth.
Estimates are that colostrum triggers at least fifty
processes in the newborn that provide lasting benefits, some a
lifetime. Quite simply, it is the most important meal in our life and
the most important food supplement we can get as an adult. It is
the only food supplement with the power to destroy viruses. As we
age or become weakened with illness, our body produces less and
less of the immune and growth factors we need to fight disease
arid heal. Colostrum can replace these life-supporting factors, in
perfect combination, to increase our longevity and enhance our
quality of life.
COLOSTRUM’S HEALING FACTORS
Colostrum is known for it’s powerful healing factors - the
Immune enhancing factors and growth enhancing factors. Many of
the components in these two factors are dependent on each other
to bring about our optimal health, but for the sake of understanding
their complexity, we will write about them separately.

IMMUNE FACTORS Colostrum contains both broad

spectrum and specific factors that help our body fight off all sorts of
viral, bacterial, fungal and allergenic invaders. Colostrum is the
only food that supplements the body with the actual critical immune
factors that the body needs to fight infection (Immunoglobulins,
Leukocytes, Cytokines, Lactoferrin, Interferon and PRP).

PRP (Polyproline-Rich Peptides) is a master regulator of

the thymus gland (in charge of producing T-cells that fight viruses
and antigens). PRP balances an underactive immune system and
an overactive immune system where the body is actually attacking
itself (MS, Rheumatoid Arthritis, Lupus, Sclera Derma and
allergies).

GROWTH FACTORS
Colostrum contains powerful anti aging and healing growth
factors (epithelial growth factor, EgF, insulin-like growth factor -1,
lgF-1, transforming growth factors A & B, TgF A & B and growth
hormone, GH).These growth factors help us build, retain and
repair muscle, bone, nerve and cartilage, balance blood sugars in
hyperglycemia and hypoglycemia, slow catabolism (burning
muscle proteins during times of fast) and stimulate fat utilization
(burning fat).
lgF-1 is believed to cross the blood brain barrier to provide
increased mental acuity and increase Serotonin uptake. The
growth factors in colostrum are the most widely researched and
reported hormonal factors in the world today. Naturally produced
by a young and healthy body but decreasing with age, growth
hormone replacement shows outstanding promise in reversing or
slowing the aging process. Anti-aging clinics around the world
have isolated some of the growth hormones, charging exorbitant
fees, for something found naturally and in PERFECT BALANCE in
colostrum.
COLOSTRUM FROM DAIRY COWS
Colostrum from humans is simply not
realistic. Human mothers are not always
healthy or free of substance abuse and we
do not know many mothers these days who
would give up any of their life giving
colostrum. We must, therefore, look to an
animal source. There are a number of
requirements for animal colostrum to be safe
and viable. The immune and growth factors
must be biologically transferable. The collection must come from a
large pool of animals to provide broad based immune factors and
commercially viable sources that assure a clean, safe gathering
process. Dairy cows are the only animals that meet all of the
criteria.
Bovine (cows) Colostrum can be used to promote passive
interspecies immunity because colostrum from cows is accepted by
virtually all other mammals, including man. For example, in the US
and Japan, researchers verified, in laboratory analysis, that IGF-1
and TgF A and B and the key Immunoglobulins (the body’s most
important immune, growth, healing and anti-aging factors) in cows
are identical in molecular combination to humans and are not
species specific but transferable from one species to another.
Furthermore, In 1979, research by Drs. Sandholm and Honkanen-
Buzalski, demonstrated that colostrum from cows is much richer in
immune factors than that from humans. Dr. C. E. Bruce later
proved that human colostrum contains only 2% IgG (the body’s
most important immunoglobulin) compared to cow’s colostrum
which contains over ten times that amount. Interestingly, the cow
(and no other animal) is able to be a universal donor and have its
immune and growth factors transferable to humans...and to other
animals (for all of you with sick pets).
Unaware of the research that has been done, many might
assume that colostrum, taken orally, would be digested like any
other protein. But, scientists have discovered, in clinical research,
in 1975 and 1994, that cows colostrum contains a special trypsin
13
inhibitor (Glycoprotein) and a protease inhibitor that shuts down
the digestive enzymes and acids that would normally digest
proteins such as immunoglobulins and growth factors, allowing
them to remain active as they pass into the bowel. It is important to
note that the digestive inhibitors are only present in colostrum
during the first 24 hours after birth. So it is critically important that
colostrum only be gathered during this time. It is also probable that
this is one of the major reasons that immune factors found in whey
are not effective in human use (they are digested for fuel).
Colostrum, however, has proven itself. In 1980, Doctor L. B.
Khazenson completed a study on human volunteers in which cow
colostrum was taken orally. Samples taken from their digestive
tracts proved that the important immunoglobulins survived the
passage and were effective in providing protection. This and a
significant number of other human medical trials, from the 1950’s
through present times, have substantiated that the oral route for
immune protection works.
Colostrum from dairy cows can be collected and specially
processed to provide all the life supporting immune and growth
factors for human use. In fact, in 1987, the International Institute of
Nutritional Research stated in a published report that: "bovine
colostrum offered tremendous possibilities for providing
unparalleled support for the immune system that may be the
deciding factor in the body's war against illness and aging."1

THE REDISCOVERY OF COLOSTRUM

Historically, bovine colostrum has played a significant role in
natural healing. It has been used in India for thousands of years.
Ayurvedic physicians and the Rishis’ have documented colostrum’s
physical and spiritual benefits. They make a candy by dropping the
colostrum in boiling water and then coating it with sugar. People in
Scandinavian and northern European countries are very familiar
with the healing benefits of colostrum. They make a delicious
pudding dessert, topped with honey, to celebrate the birth of a calf
and their good health. In the US and throughout the world, bovine
colostrum was used for immune (antibiotic) purposes prior to the
introduction of sulfa drugs and antibiotics. In the early fifties,
colostrum was prescribed extensively for treating Rheumatoid
Arthritis. In 1950, Doctor Albert Sabin, famous for the polio
vaccine, was aware of the possibilities of colostrum. He found that
bovine colostrum contained antibodies for polio (even though cows
don’t get polio). He refining these antibodies, growing them in
a cultured media and produced the first antiviral vaccine.
14
Hundreds of years of human use, thousands of scientific studies and
human clinical trials world-wide have shown bovine colostrum to be
safe and effective. Colostrum’s rediscovery and supporting research
show that we had one of the most important supplements for im­
mune enhancement and tissue repair all along.

EFFECTIVENESS OF COLOSTRUM DEPENDS

ON ITS QUALITY, AND HOW IT IS
PROCESSED
Recent research has shown that colostrum which is water-
soluble is more easily assimilated. If you are taking colostrum which
is only partially soluble, you will not get the full benefits. Colostrum
which has been frozen cannot be made water soluble and it must
be specially micronized in order to be soluble. Simply empty a cap­
sule into a glass of water. It should dissolve quickly.
Tests on several different brands of colostrum have shown
that colostrum processed with excessive heat will lose most of Its
biological activity. This is especially true of colostrum tablets. The
heat generated when tablets are formed is so high that it severely
compromises colostrum’s efficacy.
We also recommend colostrum that comes from cows that
are pesticide, antibiotic and hormone free. Artificial hormones, an­
tibiotics and other toxic chemicals can minimize the effectiveness of
the product, and create unwanted side-effects.
It is also very important that colostrum is standardized by
taking it from large numbers of healthy cows. This insures the max­
imum possible amount of immune factors. Colostrum that is not stan­
dardized is, in our opinion, hardly worth taking.
Some colostrum is manipulated to boost immunoglobulin lev­
els. Recent research, however, has shown that higher percentages
of immunoglobulin actually diminish colostrum’s effectiveness in com­
bating infection. Therefore, our conclusion is that the most effective
colostrum is that which is gently processed, but otherwise left with
the balance of its immune and growth factors as nature intended.
Finally, if possible, see if you can find colostrum that comes
from pasture-fed herds. When a cow eats healthy, green grass it
gets the live enzymes that it is naturally designed to eat, and its
colostrum contains more of these beneficial enzymes that aid in as­
similation. This helps make the many benefits of colostrum more
readily available for humans.
15
BUYER BEWARE Not All Colostrum Is
Processed In Accordance With These
Strict Guidelines
Currently no standards exist for the collection and process­
ing of colostrum. Some colostrum contains inexpensive “filler” prod­
ucts such as whey by-products, which severely reduce its effec­
tiveness. Also, if it isn’t collected during the first 24 hours after the
birth of the calf, it will be missing many of the important growth fac­
tors. To help you assess different brands of colostrum, here is a
summary of the standards you should look for in high quality
colostrum.
1. It should be full water-soluble.
2. If should come only from certified healthy, grade A dairy
cows (after the needs of the calf are met).
3. It should be collected only from the first milking after the
second birth, to ensure maximum biological activity.
4. It should come only from cows which are pasture-fed,
and certified to be hormone, pesticide and antibiotic free.
5. It should be filtered and homogenized to break down the
long-chain proteins (immunoglobulins) for better assimilation.
6. It should be mixed with the colostrum from thousands of
other cows to standardize and maximize the immune factors.
7. It should be processed to remove excess, unwanted fat,
and dried without added heat. This process is significantly
more costly and time-consuming than regular high-
temperature processing.
8. It should be laboratory tested for E.Coli, salmonella, pes­
ticides, heavy metals, antibiotics, other pathogens, a veri­
fication of high platelet count (a sign of active “friendly”
intestinal bacteria) and immunoglobulin content.
There are only a few producers of bovine colostrum which
meet the above standards. Read labels carefully, and investigate the
company. Another way to find a high-quality colostrum is to contact
the Center for Nutritional Research (CNR), an independent, non-profit
research organization. The CNR can provide, free of charge, a list
of manufacturers whose colostrum meets our guidelines. To receive
this list, send a stamped, self addressed envelope to The Center for
Nutritional Research, 4700 South 900 East, Suite #30-257, Salt Lake
City, Utah 84117.
CHAPTER TWO
CONDITIONS THAT ALLOW DISEASE TO
DEVELOP

The onset of almost all infection and degenerative disease

is preceded or accompanied by a lowered immune system
function. Our body’s immune system is designed to recognize and
destroy disease producing agents. There are several factors that
suppress our immune system and thus invite disease.

First, we inherit genetic patterns from our parents, uniquely

coded for each individual in biological strengths and weaknesses.
Our genetic weaknesses allow disease to develop when conditions
are right. Current genetic research can map a genetic
predisposition to a number of diseases. The future will most likely
unveil many more. This knowledge may encourage early detection
and possible preventive treatment.

Second, unhealthy lifestyle choices can wreak havoc

on our immune system. We suppress our immune
system with nutritional deficiencies, a sedentary life,
overwork, stress and exposure to toxins. Fortunately,
we do have some control in this area by making
health-enhancing choices.

The importance of meeting our body’s nutritional requirements has

come to the forefront with the media keeping us abreast of current
research. We are becoming more aware of how important it is to
not only balance the macro-nutrients in our diet (protein,
carbohydrate and fats) but also the micro-nutrients (vitamins and
minerals). Let us examine the effects on the immune system of
taking too much or too little of some nutrients.

Today, we hear a great deal about the importance of

antioxidants in maintaining health. Vitamin A deficiency can
actually shrink the thymus gland, limiting T-cell production (our
major line of defense against microbial attack). Vitamin E and other
antioxidants protect vitamin A from becoming ineffective through
oxidation. Vitamin C is a powerful antioxidant and effective
in fighting infection. Vitamin C protects the water soluble
micro-nutrients from oxidation by being oxidized itself. Recent
studies support the importance of protein in our diet to maintain a
healthy immune system. Essential amino acids, found in animal
proteins, need to be balanced with the nonessential proteins from
plant sources. Protein helps maintain a steady blood glucose level
in the body, that is critical for brain functions. Researchers have
recently discovered that vitamin B-12 can actually double the
body’s immune capabilities. We understand that, because of the
importance of each nutrient and their dependence on each other,
that we should eat a balanced diet. If we choose a diet that lacks
some of the nutrients our body requires, we need to supplement
our diet.

Researchers have found that nutritional deficiencies

depress inherently weak tissue and impair immune function that
can rid the body of toxic wastes that accumulate in this tissue. This
provides an open invitation for the scavengers of nature, bacteria
and viruses, to come along to feed on the dying tissue.

Without adequate aerobic and weight exercise, our body

will not function properly. A sedentary lifestyle accelerates the
aging process, dampens our immune system, slows down our
metabolism, causing us to gain weight, weakens our heart muscle
and decreases our mental acuity. We are the only ones who can
set aside time each day and make this an important priority.

An awareness of the toxins in the environment and their

effect on our health is important so that we can possibly avoid or
minimize our exposure to them. Stress and overwork seem to be
unavoidable today. We need to take an honest look at our
priorities.

The last factor is aging. As we age, our ability to fight

infection and disease decreases. Our society has placed undue
emphasis on the superficial aspects of aging: plastic surgery, hair
implants, wrinkle creams, liposuction, etc. These procedures would
be completely unnecessary if our bodies retained the healthy
immune system, hormonal balance and tissue repair of our youth.
What if there was a supplement that restored the immune system
and made it possible to combat disease, giving us increased
longevity. Since we would live longer, we would value this
supplement even more so if it improved our quality of life by
slowing down or possibly reversing the outward aging signs and
gave us more energy and zest for living. I am sure that we would
all appreciate our bodies burning fat, our muscles toning up, the
elasticity returning to our skin, our body healing faster, a balancing
of our moods and increased energy. Let’s continue. As you learn
more about colostrum, ask yourself, is it possible that there is a
fountain of youth after all?

OUR FIRST LINE OF DEFENSE AGAINST DISEASE

Our body has many mechanisms that defend against
infectious organisms (technically called pathogens). Our skin,
respiratory system and gastrointestinal tract provide the first lines
of defense. If disease organisms get past these barriers, the
immune system takes up the challenge of eliminating the invaders.
The body employs physical and chemical defenses against these
pathogens.
Skin (the tough, two layered outer membrane that protects
the body) acts as a barrier to bacteria, viruses, parasites, toxins
and other pathogens. If the skin is broken, pathogens can enter
the body and start an infection (such as staphylococci). Damp skin,
especially in warm climates, attracts various types of bacteria and
fungus. The skin's acidity along with sebum, from the skin’s oil
glands, discourage many bacteria and microorganisms.
Perspiration contains Lysozyme that destroys bacteria by eating
through the bacterial cell's wall. This enzyme is also found in nasal
moisture, saliva, tears and tissue fluid, where it destroys bacteria
and viruses

Mucus-coated nasal hairs trap germs and pollutants from

the air we breathe. Cilia (hair-like projections) guard the upper
respiratory tract. They move dust and germs that become trapped
in the mucus lining of the bronchioles (branches of the lungs)
toward the throat, where they are swallowed or expelled as
phlegm. Coughing and sneezing also help us get rid of mucus
trapped pathogens.

Mucus membranes line orifices such as the nasal and

respiratory passages, the digestive tract, the colon and the urinary
tract. These membranes, although double layered like the skin, are
not as strong or reliable at keeping out invaders. These interior
orifices are warm and coated with a liquid mucus that keeps them
from drying out but invites pathogens who thrive in warm, moist
conditions. When enough of them gather, they can break through
the membrane. Injury or irritation, sometimes caused by the
microorganisms toxic waste, also allows breakthroughs. Viruses
are so small that they can tunnel through passages meant for food
absorption.

The bowel, the most polluted part of the human body, is

the primary entrance for pathogens and toxins to invade the body.
The mucus lining of the bowel, while functioning as a barrier to
disease, is a breeding ground for harmful bacteria and unhealthy
flora. Gastric juice (hydrochloric acid) is able to destroy most
bacteria and their toxic wastes. However, it allows the friendly
lactobacillus acidophilus (acid loving) bacteria to pass into the
small intestines where they help us process nutrients and protect
our bowel.

ORGANISMS THAT CAUSE INFECTIOUS DISEASE

Disease-causing organisms reside in soil, on plants,

animals and food. They range from microscopic organisms to
larger parasites. Some of these organisms are capable of
producing disease but are kept under control by our immune
system. If our system is weak or we encounter an organism to
which we have not built up a resistance, illness can result.

BACTERIA: Round or rod shaped, microscopic, one cell

organisms that live without the need for other organisms and are
able to multiply by subdivision. When infectious bacteria enter the
body, they multiply and produce powerful chemicals (toxins) that
damage specific cells in the tissue they have invaded and illness
results. A few of the more common groups of bacteria that cause
disease are Staphylococci, Streptococci, Chlamydia, Haemophilus,
Gonococci and Rickettsia.

VIRUSES: A virus cannot reproduce on its own. In its

simplest form, it is a strand of DNA or RNA surrounded by a bit of
protein, too small to be seen even through a light microscope. It’s
presence is detected only from a boiling or bubbling of the cells
that have been invaded. Viruses reproduce and mature within the
cell’s interior cytoplasm. Viruses actually use body cells as
factories to reproduce more of their kind. When they mature, the
viruses explode the cell’s wall, destroying the host cell and
infecting nearby tissue. The cycle is repeated and the infection
spreads. Polio, AIDS, hepatitis, chronic fatigue syndrome, the flu
and the common cold are a few of the viral diseases.
 FUNGI: Molds, yeasts and mushrooms are fungi. Only
certain yeasts and molds are infectious. Candida albicans is one
virulent example. It produces thrush (infection of the mouth and
throat) in people who have received antibiotics or have impaired
immunity. It also infects the bowel, robbing the body of essential
nutrients and can lead to Leaky Gut Syndrome.

PROTOZOA: Single-cell organisms that live within the

body, usually in the intestinal tract as a parasite. Most are
harmless, although some may cause disease (malaria).
HELMINTHS: Large parasites that take up residence in
the intestinal tract, lungs, liver, skin and even the brain. The most
common Helminths are tapeworms and roundworms.
2 2
CHAPTER THREE
THE IMMUNE RESPONSE
The field of immunology is ever expanding. In its earlier
history, immunology mainly dealt with antibodies and vaccines.
The science later broadened to studies of antigen/antibody
reactions. More recently, cellular immunity is recognized to have
important implications in aging, heredity, growth, transplantation of
organs, cancer and infectious disease. The world in which we live
contains a myriad of foreign substances that confront our immune
system and trigger it into action. Infectious agents attack the body.
As they try to gain control of vital cells, tissues and organs, life
threatening conditions may result. At such times, our bodies set up
defenses to protect vulnerable locations. This protection is known
as the immune response.
When an infectious organism enters the body, whether it is
a bacterium, virus or toxin, it quickly comes across one of the
defenders of the body, called leukocytes (white blood cells). There
are many different types of white blood cells which can multiply
very quickly in times of infection. An elevated white blood cell
count usually indicates that we have an infection present. The
intricate networks of the lymphatic and circulatory systems carry all
of these leukocytes and many chemical messages throughout
every part of our body to sites of infection.
There are two categories of immune response: Humoral
immunity and cell-mediated immunity.

HUMORAL IMMUNITY
Humoral immunity is based on certain long chain proteins called
antibodies (immunoglobulins), which are found in blood and other
body fluids. These antibodies are made by plasma cells, which are
derived from certain white blood cells called B lymphocytes (B
cells). The antibodies are produced in response to exposure to a
foreign substance. Any foreign substance that enters the body
through our digestive system, by injection or through a wound,
causing the manufacture of antibodies, is called an antigen. The
antibody produced will fit the antigen much like a key fits a lock
and neutralize that foreign substance or render it harmless. The
antibody is a small bit of protein, smaller than bacteria, that sticks
to the antigen like glue and cannot be shaken off.
2 3
After the antibody locks onto the antigen, it changes shape to
attract complement (protein found in blood serum), which releases
a chemical that penetrates the antigen’s cellular wall and kills it.
Antibodies are specific in that each is effective against the antigen
that caused its creation.
A good example of how antigens create antibodies to
protect our bodies is immunization. A toxoid (toxin that has been
rendered harmless to your body but is still capable of producing
immunity) in a carefully determined amount is injected into the
body. The body recognizes the toxoid and responds by creating
antibodies that will neutralize the toxic substances produced by it.
Within a few weeks, these antibodies begin to circulate in the
body’s fluids and will usually persist for many years. Once the
body has learned to produce a particular antibody, it can resume
production of that antibody quite rapidly. Sometimes a booster shot
is recommended in later years to stimulate the production of
protective amounts of these antibodies. Antibodies also bind
several viruses together into antigen/antibody complexes that
make it easier for phagocytes (scavenger cells that ingest
antigens) to find and consume them. Antibodies help phagocytes
and killer cells destroy infected cells by attaching themselves to
the surface of the antigen.

CELL- MEDIATED IMMUNITY

Cells of the immune system are specialized white blood
cells called leukocytes. One type of leukocyte matures in the
thymus, so it is called a T lymphocyte (T-cell). T-cells acquire
specialized functions and become killer cells, helper cells and
suppressor cells. Natural killer lymphocytes (NK cells) and
phagocytes (scavenger cells) originate in the bone marrow. Other
types of cells originating from the bone marrow amplify immune
effects. These are the mediator cells. These different cells, along
with chemical protein defenders (Complement, Properdin and
Interferon) and antibody play vital roles in our immune defense.
They all interact to protect cells that are under attack from
infectious agents such as viruses, fungi, cancer cells and other
pathogens.
T-cells are white blood cells that are involved in cellular
defense, derived from the thymus gland (master control of the
immune system). There are three kinds of T-cells, each with
a specific function: killer T-cells, helper T-cells and suppressor
T-cells.
 Killer T-cells seek, lock onto and destroy body cells that
are infected by releasing a chemical poison.
Helper T-cells (macrophages) increase the number of
cells that can engulf or dissolve foreign particles in response to an
infection. They also facilitate the production of antibodies by
stimulating growth and activity of B cells.
Suppressor T-cells regulate the B-cells’ production of
antibodies.
Natural Killer Lymphocytes (NK) are specialized green
beret like forces that survey many areas of the body, killing virus
infected cells. These natural killers also play a major role in
surveying and destroying cancer cells. Small numbers of cancer
cells are continually being destroyed in the body and it is only
when conditions are unfavorable for defense that they increase.

Phagocytes are divided into two classes: macrophages

that ingest bacteria and macrophages (scavengers) that ingest
foreign particles (in response to infection), dead tissue and
degenerative cells.
Mediator cells carry biologically active molecules that
slow blood flow and widen pores in blood vessels to help the
fighters leave the blood stream and move into battle.
Lymphocytes are aggressive cells that have two key
strategies. They directly kill infected cells or they resort to chemical
warfare, releasing substances called Lymphokines, that mediate
immune responses and Lymphotoxin, a toxic substance which
poisons and kills infected cells. Lymphocytes are found in the bone
marrow, in the spleen, circulating in the blood and in the lymph
nodes. The lymph nodes are collections of lymphocytes, held
together by connective, fibrous tissue. Lymph nodes are located in
the neck, groin and armpits, where they can be felt if they become
firm and enlarged in the course of a disease or infection. Other
lymph nodes are found in the abdomen and at the center of the
lungs. Lymph is a colorless fluid that runs in channels in all parts of
the body to and through the lymph nodes and ultimately into the
bloodstream. The lymph nodes constitute a partial barrier to
organisms that may be traveling in the lymph. These cells grab and
destroy antigens as they pass by. Some lymphocytes energetically
hunt for virus infected cells in the blood and lymph circulatory
systems. They puncture holes in the cell’s membrane which
causes the cytoplasm to leak out and eventually kills the cell.
The active lymphocytes select and kill only target cells that are
infected by viruses, leaving normal, healthy cells intact.
The immune system is a complex defense system for
suppressing and eliminating infections. At the same time,
infectious organisms have complex offensive systems. The result
is a constant battle between your body and infection,
a battle your body usually wins, but not always.
CHAPTER FOUR
COMPONENTS OF COLOSTRUM
Major drug companies and research centers,
world-wide, are looking seriously at the

O
natural process of immunity, with their focus
on colostrum. Research is continually
discovering new important components in
colostrum. We will see a great deal of
publicity (Medical press), as information
expands. Robert Haley, MD, head of the
Epidemiology and Preventative Medicine Unit
at the University of Texas, in Dallas, stated in a published letter in
August, 1995, “the very technology that saves peoples lives, sets
them up for infection". Antibiotic resistant organisms are an
integral risk of any infection. About the time that the price of an
antibiotic comes down, the bacterium’s resistance to it goes up.”2
After forty years of aggressive antibiotic abuse, physicians are now
confronting bacteria that have mutated defenses against drugs,
causing deaths of patients who succumb to once treatable
infections. Even with the thirty or so antibiotics that the drug
companies claim to be working on, there are no more potent
antibiotics left to treat these drug resistant bacteria. Jeffrey Fisher,
in his book, 'The Plague Makers,’ (Simon and Schuster, NY),
suggested that antibiotics, taken in successive and prolonged
doses, may suppress the immune system enough to allow unusual
forms of Mycoplasma bacteria to develop. He warned that these
bacteria have been shown to interact with the Human
Immunodeficiency Virus (HIV) to form (develop) AIDS. Further,
antibiotic abuse is not just a human phenomenon. Animals are
constantly being fed antibiotic laced feeds and are undergoing
injections in an effort, by commercial producers, to ensure the
animal’s growth and survival until it reaches market. Without
antibiotics, the chicken, beef, pork and lamb that you eat would not
be so plentiful, and therefore, would probably be much more
expensive. The problem is, when we consume these meats, we get
residuals of the antibiotics and pesticides that the animal
consumed and our bodies become desensitized to their constant
presence. When we really need an antibiotic, we’ll need more and
more powerful varieties to do the job.
 It’s coming down to the fact that there may be only one
viable solution to protect ourselves against these super mutants -
colostrum’s natural immune factors - that stimulate and increase
the capability of our immune system. Recently, scientists
discovered that colostrum’s primary benefit is in building the
immune system so it can function, with strength, on its own. Doctor
Julius McGill, in Montreal, reported, in 1994, that colostrum speeds
the growth and production of our body’s own B Lymphocytes (white
blood cells) and primes them for production of antibodies.
Furthermore, it activates macrophages in our blood that work with
killer T-cells in identifying and destroying viruses.

IMPORTANT COMPONENTS IN COLOSTRUM

Immunoglobulins (antibodies) are powerful specific

and broad spectrum antiviral and antibacterial defenders. Their
use in the treatment of disease is not new. Immunoglobulins (also
called Immunoglobins and Gammaglobulins, depending on the
source) are currently being used in hospitals, throughout the world,
to treat hospital acquired infections and other disease. In fact, in
1992, The New England Journal of Medicine reported that this
fighter (immunoglobulins IgG) is so important that its use has been
extended to treat a wide variety of infections and immune disorders
including hepatitis A, Chickenpox, Cytomegalovirus, Rheumatoid
Arthritis, Multiple Sclerosis, Anemia, Thrombocytopenia,
Neutropenia, Myasthenia Gravis, Guillain Barre Syndrome,
Systemic Lupus, Bullous Pamphigoid, Kawasaki’s Syndrome,
Chronic Fatigue Syndrome and Crohn’s’ disease, among others.

Immunoglobulins are the most important and abundant

immune factors found in colostrum. They are large protein
molecules, made of amino acids, that are soluble in saline
solutions but not in pure water (powdered colostrum will not
dissolve in water). Immunoglobulins normally make up about 45%
of the proteins in our blood serum. There are five classes of
immunoglobulins found in all mammals, including humans. They
begin with the abbreviation Ig and are distinguished from one
another by a following capital letters (A, D, E, G, and M). Each has
its own unique structure and job to do in the body. These
immunoglobulins are protein chains that are make up of hundreds
of amino acids. One of the most important linking and active
components of immunoglobulins is sulfur (a mineral that is very
important to our metabolism) that is also highly antibiotic.
 Colostrum contains all of the immunoglobulins. IgG (the
most abundant immunoglobulin found in colostrum) is carried in
the lymph and circulatory systems where it is effective in
neutralizing toxins and other invaders. We find secretory IgA (S-
IgA) in saliva, tears and Mucus membranes. A second type of IgA
operates in the blood serum. IgM is known to destroy bacteria. IgE
and IgD are highly antiviral.

Immunoglobulins are found separately and in innumerable

combinations. Each type and combination is able to attach to,
penetrate, destroy or immobilize a specific antigen. The mucus
membranes of the body are coated with Immunoglobulins that help
provide a barrier to invading organisms. If antigens get past the
Ig’s on the mucal surfaces, they have to face IgM and IgG
immunoglobulins in the body. Immunoglubulins that circulate in the
lymph and blood are particularly effective at destroying bacteria
and viruses.

After a human or a cow has successfully overcome a

disease, it carries an immunity for that disease for many years,
even a lifetime. Immunity is passed on to the offspring through the
placenta and the colostrum. Humans pass on most of this immunity
through the placenta, whereas, cow immunity is not passed
through the placenta but through the colostrum. This is why cow’s
colostrum has 10-20 times more immune factors than human
colostrum and why the calf probably would not survive without it.

The majority of immunoglobulins are found and produced

in the bowel. In 1994, clinical research on adult human subjects
showed that IgG not only stays in the bowel but penetrates the
small intestine and enters the blood stream. Immunoglobulins are
not only an essential part of the body's Humoral immunity but once
inside the body, they provide internal immunity.

Lactoferrin is one of the most powerful antiviral,

antibacterial substances, found naturally, only in bovine colostrum
(not species specific)

Lactoferrin is an iron-binding protein found on the

mucosal surfaces and in the blood serum, where it is needed to
work. It has been shown to play a major role in our body’s defense
against disease, infection, cancerous tumors and HIV, (Cancer
Biotech Weekly, March, 1995). One of the most important
functions of Lactoferrin is its iron binding and releasing capability.
Bacteria require iron to reproduce. Lactoferrin locks onto the iron
ingested, depriving the bacteria of the iron needed to reproduce. It
then releases this iron to the red blood cells, where it acts as a
vital catalyst in providing oxygen to all cells in the body.

Lactoferrin binds directly to bacteria, inactivating them and

increasing bacterial membrane permeability so that they can be
neutralized by the body’s natural immune functions. High affinity
Lactoferrin receptors have been identified on most immune cells
(Lymphocytes, Monocytes, Macrophages, and Platelets). It is also
involved in the regulation of Cytokine release. Lactoferrin is highly
resistant to digestion, passing nearly intact to the intestine where it
works. Lactoferrin has actually been shown, in numerous clinical
studies, to be more powerful than immunoglobulins in it’s
bacteriostatic and antiviral actions.

Doctor Harmsen’s clinical research (in-vitro), conducted

in 1995, emphasizes that the source of Lactoferrin is very
important. His studies showed Lactoferrin to have potent activity
against human HIV and Cytomegalovirus. His report further states
that, “Only native and intact Lactoferrin from bovine colostrum or
human milk could completely block a Cytomegalovirus infection."
Native (not synthetic) Lactoferrin also inhibited the growth of the
Human Immunodeficiency Virus (HIV). The study showed that
Lactoferrin exerts its effect at the viral absorption level, preventing
the penetration of the cell and reducing further viral migration.

Lactoferrin contains antibodies against a wide range of

bacterial, fungal, viral and protozoal pathogens. Lactoferrin, also,
is a super antioxidant that inhibits free radicals. Current studies
have shown that Lactoferrin contains an anti-inflammatory
molecule that plays a role in lessening ocular disturbances, acts as
a potent antimicrobial agent against Candida albicans, possesses
a potent antiviral activity useful in preventing and treating herpes,
HIV, Chronic Fatigue Syndrome and other viral disease and shows
promising results with the autistic and brain-injured.

Proline-rich Polypeptide (PRP), is the regulating

hormone for the thymus gland. It is one of the most important
immunological peptides in colostrum. It is critical for those with
autoimmune disease and allergies. It balances an overactive
immune system (where the body attacks itself or is producing too
many antibodies) and stimulates an underactive immune system.
 Insulin-Like Growth Factors and Transforming Growth
Factors. Studies completed in 1995 show that the biological
activities of lgF-1 include direct stimulation of T-cell production.
lgF-1 also accelerates healing, balances blood sugars
(hypoglycemia and hyperglycemia), reduces insulin needs,
stimulates muscle growth and regeneration, stops or slows
catabolism (the body metabolizing its own muscle protein in times
of fast) and increases the metabolism of fat for fuel.

Leukocytes. Leukocytes stimulate the production of

interferon (slows viral reproduction) and inhibit the viruses
penetration of the cellular wall.

Lactoperoxidase-thiocyanate, plus Peroxidase and

Xanthine Oxidase Enzymes. Discovered by Dr. Moldoveanu, in
1983, that they oxidize (burn up) bacteria by generating the
release of hydrogen peroxide.

Lysozyme. A powerful hydrolyzing agent, resistant to

acids, that destroys bacteria and viruses on contact. It is found in
perspiration, saliva and tears. In recent years, it has been added to
infant formula to boost immune capability.

Cytokines. Cytokines are composed of Interlukins that

regulate the intensity and duration of immune responses and are
responsible for cell to cell communications. They boost T-cell
activity, regulate lymph activity, stimulate production of
immunoglobulins and are highly antiviral and anti-tumorous.

lnterlukin-10 (one of the Cytokines) is a powerful

inflammation inhibitor that significantly reduces inflammation in
arthritic joints and infected or injured (surgical or trauma) areas of
the body.

Glycoproteins and Trypsin Inhibitors. Their primary role

is to keep the immune and growth factors, found in colostrum, from
being digested in their passage through the stomach and the
beginning areas of the small intestine. They also prevent
Helicobactor Pylo’ri Bacteria (shown to be the cause of stomach
ulcers) from attaching to the stomach wall.

Lymphokines. Lymphokines (released by activated

lymphocytes) are hormone-like peptides that mediate immune
response.
 Oligo Polysaccharides and Glycoconjugates. In 1983,
Dr. L. A. Hanson demonstrated that there are saccharides (sugars)
in colostrum that attract and bind to pathogenic bacterial invaders
and prevent them from attaching to or entering the body’s
(intestinal) mucus membranes. They, along with the other
components of colostrum, are very effective in blocking attachment
of Streptococcus Pneumococci, a major cause of lung
inflammations and middle ear infections and pathogens associated
with Leaky Gut Syndrome: E. coli (the infamous hamburger
pathogen), Salmonella, Cryptosporidia, Giardia and Entamoeba
(cause traveler’s diarrhea), Shigella, Clostridium Difficile Toxins A
& B, and even the super toxic bacteria that causes diarrhea in
Cholera.

Orotic Acid. Orotic Acid, an important mediator, that has

been shown to stop the formation of Pyrimidine Nucleotides, thus
preventing the onset of hemolytic anemia (degeneration of the
blood).

Other immune factors. Colostrum’s immune factors

include many other components. In 1994, a group of doctors
researching colostrum’s immune capabilities reported that
colostrum contains a powerful mixture of immune factors
(Immunoglobulins IgG, IgM, IgA and IgE, large amounts of
secretory IgA, IgA Specific Helper which induces IgA synthesis, B
Lactoglobulin, Lactalbumin, Lactoferrin, Albumin, Prealbumin,
Alpha 1-Antitripsin, Alpha 1-Fetoprotein, Alpha 2-Macroglobulin,
Haemopexin, Haptoglobin, Beta 2-Microglobulin, Alpha 2-AP
Glycoprotein, C3, C4, and Orosomucoids).This incredible list of
powerful immune factors, in perfect combination, is solely unique
to colostrum and cannot be duplicated as a drug.
CHAPTER FIVE
COLOSTRUM AND DISEASE

Colostrum provides its most powerful benefits where

almost 80% of all disease and infections enter the body, the
mucosal surfaces. Researchers at West Virginia University Of
Medicine and Pharmacy confirmed that most infectious disease
enters the body through or remains localized on mucosal surfaces.
The largest mucus membrane of the body is the intestinal tract.
Peyer’s Patches, located in the bowel and lungs, produce
antibodies to stop disease on the mucus membranes and in our
circulatory system. Over 70% of our antibodies are produced by
the Peyer’s Patches in the bowel. Historically, we’ve virtually
ignored the bowel. It is obvious that we must focus on this area if
we are serious about preventing disease.

Disease or infections in the bowel are a direct link to

infections in the lungs and bronchioles. Immunoglobulins, in
colostrum, stimulate the production of antibodies at the Peyer’s
Patches in the intestines and lungs, where they coat and protect
tissue and destroy pathogens, toxins and allergens. It is interesting
to note that in 1980, Dr. David Tyrell, while conducting research on
colostrum at the Clinical Research Center in England, discovered
that most of the antibodies in colostrum are not absorbed but
remain in the intestinal tract after being swallowed. There they
attack disease causing organisms, toxins and chemical irritants
and destroy them before they can enter the body.

In recent years, the flood of antibiotics, antihistamines and

sulfa drugs have virtually destroyed the beneficial bacteria in the
bowel. This has hampered their specialized immune systems,
making them less effective and allowing highly virulent bacteria life
to take over. With each antibiotic use, immune function is lowered.
When antibiotics are stopped, the immune system is weak and
vulnerable until it builds up again. There is only so much toxicity
and germ life the bowel can handle before the lungs and
bronchioles are affected. The toxic overload today is so great that
normal defenses and acidophilus bacteria are at the point of being
overwhelmed.
Colostrum has the proven ability to fight disease, promote healthy
intestinal microflora, increase nutrient absorption, reduce gas and
bloating and stop Leaky Gut Syndrome.

LEAKY GUT SYNDROME

The contents of the gut contain
DANGER a toxic antigenic mixture from which the body
needs to be protected. Protection is provided by
CONTAMINATED a mucosal epithelium barrier and Secretory IgA
4.4 AREA 4 .4 (Immunoglobulins) Leukocytes. All substances
4 4 that by-pass this barrier must pass through the
liver, where they are filtered out of the body’s
circulation. Any that enter through penetrations in the gut wall are
removed by phagocytosis, oxidation and the conjugative actions of
Glycine and Glutathione, excreted in the bile. The cost of
detoxification is high. It consumes reactive intermediates and
antioxidants. The excretion of oxidation by-products into bile and
its recirculation into pancreatic ducts is considered to be the major
cause of pancreatic disease.

Leaky gut means increased intestinal permeability.

A compromised intestinal barrier causes diarrhea and other
diseases. It also creates allergies to food substances and normal
bowel flora. In experiments with animals, it has been shown to
produce autoimmune disorders. Diseases associated with
increased intestinal permeability include: Crohn’s disease, Irritable
Bowel Syndrome, Diarrhea, Cholera, Inflammatory Bowel Disease,
Salmonella and E. coli infections, AIDS, Chronic Arthritis, Chronic
Fatigue Syndrome, Hepatitis, Cystic Fibrosis, Pancreatitis, Autism,
Hyperactivity, Chemical Sensitivities, Environmental Illness,
Alcoholism, Infectious Enterocolitis, to name a few, plus, skin
diseases such as Acne, Dermatitis and Psoriasis. Gut permeability
not only plays a primary role in the evolution of disease but has a
secondary consequence, impaired immune function that leads to
additional infections and disease.

Leaky Gut Syndrome is usually caused by exposure to

infectious agents such as viruses (HIV, rotavirus), bacteria (E.
coli), yeasts (Candida), protozoa and various toxins. Additional
causes are ethanol (alcoholic beverages), anti-inflammatory
drugs,
elevated levels of oxygen metabolites (food borne or produced by
inflammatory cells), cytoxic drugs, increased intra (para) cellular
permeability, plus, reactions from heart attack, surgeries and
shock.

The relationship of leaky gut to food allergies can begin

early, with ingestion of allergens in food as infants. Indications are
that colostrum and continued breast feeding mitigates (prevents)
intestinal permeability and can prevent the onset of allergies,
diabetes and Leaky Gut Syndrome.

Intestinal cellular wall disturbances disrupt normal

transference of nutritional absorption. Malnutrition then occurs,
aggravating cellular repair and immune functions. The metabolic
demands of healing must be met or infections, disease and bowel
permeability exacerbates.

Leaky Gut Syndrome often goes unrecognized. Today

there are several safe, noninvasive means to test intestinal
permeability and monitor treatments.

Colostrum can stop Leaky Gut Syndrome. Its combination

of components are unique and unsurpassed. Colostrum’s
immunoglobulins (IgA, IgG and IgM), Lactoferrin and other immune
factors stop the reproduction and penetration of antigenic invaders
and toxins. Its epithelial growth factors stimulate cellular repair of
the intestinal barrier and its anti-inflammatory action reduces
cellular spacing, stopping hyperpermeability. We also need to
address and correct nutritional deficiencies with a nutrient rich diet,
the addition of fiber for proper bowel passage, the elimination of
allergenic foods, enterotoxic drugs and antibiotics if we are to aid
and rebuild proper immune functions.

BACTERIA
The University of Texas Medical School conducted studies
that showed colostrum was able to neutralize not only bacteria and
viruses but their toxins. In human clinical trials, it was shown that
toxins from the deadly bacteria, Clostridium (a bacterial family that
includes tetanus and botulism), were neutralized with bovine
colostrum.
 There are several varieties of the common bacteria
E. coli, found in the bowel, some of which are very dangerous.
E. Coli causes diarrhea and is highly irritating to the bowel
because of its toxic metabolic wastes. Researchers at the
University of Alabama showed that IgA, Lactoferrin and
Peroxidase, found in colostrum, were very effective against the E.
Coli. bacteria. Additional research showed that colostrum’s IgG
and other proteins prevented the growth of E. Coli and neutralized
its highly toxic wastes, preventing infection and diarrhea.

Both IgA and IgG provide demonstrable protection against

cholera (acute epidemic, infectious disease causing
gastrointestinal disturbances). At Ohio State Children’s Hospital,
colostrum from cows, exposed to cholera, protected children
against contracting the disease.

Doctors at New York State University, Buffalo, NY, have

listed a number of dangerous bacteria commonly found in the
intestine that are controlled by colostrum (E. Coli (the infamous
hamburger pathogen), Salmonella (food poisoning), Shigella,
V. Cholera, Bacteriodes Fragilis, Streptococcus Pneumo’niae,
Bordetella Pertussis, Clostridium Diphtheria, Clostridium Tet’ani
and Streptococcus mutans)

CANDIDA ALBICANS
Candida albicans (yeast) infections usually

Â
occur after the use of antibiotics. When this
infection invades the digestive system, healthy
microflora are overcome, nutrient absorption
becomes restricted and the immune system is
severely weakened. According to a study from
the University of Hong Kong, published in
Pediatrics in 1978, colostrum showed a
presence of leukocytes that were effective in controlling the yeast
infection Candida albicans. In 1987, doctors reported in the New
York Annals of Medicine that colostrum was quite effective against
Candida albicans. Lactobacillus Acidophilus and Lactoferrin,
which are present in colostrum, are also powerful agents against
this destructive intruder.
ALLERGIES AND AUTO-IMMUNE DISEASES (MS,
RHEUMATOID ARTHRITIS, A.L.S., LUPUS,
PERNICIOUS ANEMIA, MYASTHENIA GRAVIS)

Autoimmune diseases and allergies are caused by an over

reaction of the immune system, producing too many antibodies in
response to an antigen. Autoimmune diseases are a medical
dilemma, as are allergies. This immune response can be toned
down with one of the most powerful components in colostrum, PRP
(Proline-rich Polypeptide).

In Warsaw, Poland, 1993, research on colostrum led to

the discovery of a new immune regulatory peptide, PRP. The
research showed that PRP was non species specific (PRP in cow’s
colostrum can benefit humans). It is able to transform cortisone-
resistant thymocytes (T-cell precursors) into cortisone-sensitive
and vice versa. It increases permeability of skin vessels and
causes differentiation of murine thymocytes into functionally active
T cells. It can simultaneously change surface markers and
functions of cells, producing results in auto-immune disorders and
sarcoma (cancer). The researchers reported that the regulatory
substance PRP-3b offers enormous possibilities to support the
body’s thymus gland in balancing the immune system, especially in
those cases where the immune system is overactive and attacking
the person’s own body, as is believed to be the case in rheumatoid
arthritis, MS, A.L.S., Lupus, Sclera Derma, etc. Abnormal T-cells,
in this out of control response, can create tremendous
inflammation and debilitating pain as it destroys the body’s
connective and peripheral tissues. PRP inhibits overproduction of
T-cells and lymphocytes, stimulated by antigens and mitogens,
stops the progress of the attack and thereby reduces the
associated pain and swelling. The doctors further stated that here
at last was an all natural source of nutritional factors which may be
able to stop this over reaction (allergic and autoimmune) and
return the balance back to normal.

The two types of growth factors in colostrum should help

repair the damage of auto-immune diseases. Epithelial growth
factor should help reverse the destruction of skin cells, that can
occur with lupus. Transforming growth factor, found in two forms in
colostrum, can help reverse protein breakdown and stimulate
tissue repair.
VIRUSES
Colostrum is the only supplement that will destroy
viruses, something no other food supplement or drug can yet
do. Bovine Colostrum has been shown to be effective in its
ability to stop colds, herpes, cold sores, flu viruses, viral
bronchitis, viral pneumonia, RSV and chronic fatigue
syndrome.
What is a virus? Viruses are nothing more than little pieces
of RNA, that move about the world, looking for a place to hide and
grow. They are practically indestructible and can sometimes retain
their capabilities to reproduce for days or even years in
environmental conditions that would kill bacteria. Viruses, each
unique in its ability and needs, have one thing in common - they
need animal or human cells to replicate. Therefore, in order to
combat them, we must either stop them before they enter the
cellular structure (humoral immunity) or after they have entered, by
destroying the cell in which they live and multiply (cellular
immunity). Colostrum has a wide range of antiviral factors
(Immunoglobulins, Lactoferrin, Cytokines, etc.) that are very
effective and work at both levels.
HIV VIRUS (AIDS)
Antibodies and leukocytes kill viruses but they can’t stop
the virus that attacks the immune system itself, HIV (AIDS). This
virus mutates so quickly that the immune system is unable to
produce antibodies and T-cells fast enough to cope and is
eventually overcome. The final result is that the AIDS patients
come down with opportunistic infections that they are no longer
capable of handling, because the immune system is so weakened
from fighting the HIV. Components in colostrum have shown their
unique ability to help, even with this rapacious killer. Colostrum
has been proven in numerous clinical and human trials to be
effective with the opportunistic infections, even when virtually all
other treatments failed. We now believe that colostrum will benefit
the AIDS patient by prolonging life, if started early and taken
consistently after diagnosis.

When AIDS is contracted, immune functions in the bowel

are severely reduced and one of the earliest symptoms is chronic
diarrhea. Diarrhea is a major reason why AIDS patients become
immune compromised. Chronic diarrhea not only reduces our
ability to fight infections (70-80% of our body’s antibodies are
produced by the Intestinal Immune System) but drains our body of
vital nutrients, electrolytes and body fluids. The body, without
proper nutrition, produces cortisol which causes catabolization
(eating its own muscle for energy). The terrible downside to this is
that cortisol is highly immunosuppresive, so that an already
severely weakened immune system is even further suppressed.
The effects of this process can be seen in the gross weight loss
(wasting) that is so evident with this terrible disease. The only way
to stop this process is to remove the pathogen and heal the
intestinal penetrations they cause. Colostrum contains all of the
natural components to not only stop this pernicious process but
prevent it in the first place. This is not true of some potentially
toxic, anti-diarrheal remedies. Self medication with brand name,
over-the counter treatments containing bismuth compounds
( heavy metal agents) can stop the flow of fluids both ways across
the intestinal wall, reducing nutritional uptake. These treatments
do not remove or kill the pathogen and with prolonged used can
cause brain damage. Other remedies like Loperamide simply
reduce the flow of water, do nothing to heal the ulcerated intestinal
wall and may even increase the duration of the disease. Colostrum
is the key to keeping the gut pathogen free and functioning
optimally.

Hospital use and clinical tests have shown bovine

colostrum’s effectiveness in treating opportunistic infections
associated with AIDS. Tests with regular (non-hyperimmune) and
hyperimmune colostrum( where the cow is injected with a specific
pathogenic virus or bacteria, producing specific immune factors for
that invader) have shown both to be highly successful.
Interestingly, studies using double blind human trials for treatment
of (diarrhea causing) Cryptosporidia and rotavirus showed that
hyper-immune colostrum was only 15% more effective than regular
cow colostrum (67% versus 82%). Hyper-immune colostrum is in
short supply and only available under hospital supervision.

Additional benefits come from one of colostrum’s major

components: Lactoferrin. The HIV-infected immune system
displays elevated levels of a powerful immune suppressant
(Isoferratin) that is also encountered in the maternal serum and
uterine environment during pregnancy. Isoferritin down-regulates
the immune system so that the fetus (which contains foreign
antigens to the mother’s system) won’t be aborted. Lactoferrin
(a natural component in colostrum) suppresses and reverses the
effects of Isoferratin and turns on the immune system with the birth
of the baby (it does the same thing for the adult AIDS patient).
Lactoferrin also inhibits the growth of HIV by preventing viral
penetration of the cell. Elevated levels of isoferritin are also found
in patients with certain lymphomas, leukemia, renal and celiac
disease, and those who have endured radiation and cancer
therapy for cancer.
HEART DISEASE
s The New England Journal Of Medicine, in its
April 21 issue, 1995, reported that many
cardiac diseases are the result of immune
sensitization to cardiac antigens (damaged
heart muscle), leading to myocarditis
(inflammation of the muscular walls of the
heart). Heart muscle tissue dies after it is damaged in myocardial
infarctions. The body then produces antibodies for these new
antigens (dead heart muscle), producing a condition similar to an
autoimmune response. PRP, with its ability to balance overactive
immune functions, and the other anti-inflammatory components in
colostrum can lower the risk of additional heart attack by lessening
the body’s response (attack) to this damaged tissue and the
associated inflammation of surrounding heart muscle.

Cellular immunity, rather than Humoral, has been the focus

for most of the research conducted on immune related heart
disease, with lymphocytes and macrophages being the
predominant infiltrating cells. Cardiac disease associated immune
mechanisms include (giant cell associated) cardiomyopathy and
primary idiopathic myocarditis. Recent research reported in the
Journal of the American College of Cardiology reported that a
common type of Chlamydia bacteria was linked to the formation of
arterial plaque in over 79 percent of patients with heart disease.
Other research aimed at discovering the mechanisms of how
myocardial infarction (heart attack) affects muscle cell functions
and rearranges myocardial (heart muscle) cell architecture is
leading to more and more emphasis on immune functions
relationship with heart disease.

lgf-1 and GH, in colostrum, have been shown to lower cholesterol

levels by lowering LDL concentrations (sign of high heart attack
risk) and increasing HDL concentrations (unique in reducing heart
attack risk). Growth factors have the unique ability to promote the
healing and regeneration of (heart) muscle tissue and have been
shown to stimulate the regenerate of new blood vessels. These
factors can be significant in the acceleration of recovery.
CANCER
Cancer, the causes of which are many, is in great part due
to cellular damage from genetic predisposition or toxic build-up.
Viruses seek out damaged cells to enter for reproduction. The
older we get, the more damaged cells we have. Most cancers are
caused by thousands of different viruses that can either, with
enough damaged cells, replicate too quickly for our immune
system to control or have the ability to shut down the normal
immune response that destroys these invaded cells. Colostrum can
boost this immune response and provide components that work
against these viruses at both the cellular and the humoral level.

In 1985, Steven Rosenberg made quite a splash with his

sensational book, ‘Quiet Strides in the War on Cancer’, with
emphasis on the benefits of Cytokines in the treatment of cancer.
Colstrum, quite uniquely, contains many of these natural
Cytokines: Interlukins 1, 6 and 10, Interferon G and Lymphokines.
Currently, The Cytokines are the single most researched protocol
in our search for cancer's cure(s). Colostrum provides an
incredible mix of immune and growth factors that limit and inhibit
the growth of cancer cells, prohibiting initial infections and possibly
destroying (infected) tumorous cells.

Additional components provide help in other ways. In

August, 1995, doctors in Sweden reported results from a research
study that mother’s milk and colostrum contains Lactalbumin
(Multimeric a), found to have the unique ability to cause cellular
apitosis (suicide) of cancerous cells, leaving the surrounding
tissues untouched. Colostrum also contains growth factor TgF-B,
that shows cytoxic effects (kills them) on anchorage dependent
human Osteosarcoma (cancer) cells and lgF-1, necessary for the
growth of all cells in the body, including cancer and immune cells.
Recent experiments show that the presence of cancer cells
stimulates a reaction of growth hormone that mobilizes large
numbers of Polymorphonuclear Leukocytes to come and engulf the
cancer cells.
Also, Lactoferrin (a major component of colostrum) has
unique abilities to fight cancer and other disease. Reports in
Cancer biotech Weekly (March 1995) reported that initial studies
were over; the jury was in: clinical and laboratory tests validated
the use of Lactoferrin in the treatment of cancer.
 Chemotherapy and radiation severely compromise the
immune system, putting patients in grave jeopardy from infection,
especially in the bowel. One of the most devastating symptoms of
gastrointestinal infections is chronic diarrhea, depleting the body of
water, electrolytes and life-supporting nutrients. Cortisol is then
produced to signal the body to live off stored nutrients at the cost
of being highly immunosuppressive. Colostrum stops this process,
restoring nutritional absorption and rebuilding resistance and
strength, so desperately needed to survive the treatments and
protocols prescribed for cancer today.

DIABETES AND HYPERGLYCEMIA

Juvenile Diabetes is currently thought to result from an

allergic reaction to the protein GAD, found mostly in cow’s milk.
This reaction has been shown to occur in children who did not
receive human colostrum and a long enough course of breast
feeding (colostrum and mother’s milk contains factors that can
offset an allergy to GAD). In 1995, mice treated in clinical trials
with a monoclonal anti-CD3 antibody, have been able to resume
normal regulation of their blood sugar. Whether this will work in
humans is hopeful, but not conclusive at this time.

Colostrum helps offset all allergic reactions in our body.

Colostrum contains the growth hormone (GH) and insulin like
growth factor-1 (lgF-1). GH has been shown to inhibit insulin
stimulated glucose disposal by 27%. Also, when present, it raises
nonprotein energy expenditures (fat oxidation) from 48% (without)
to 71.7% . Colostrum contains natural insulin and insulin like
growth factor (lgF-1) that both bond with the insulin and lgF-1
receptors found on all cellular structures in the body. In 1990,
Doctor Elton Dohm reported that, based on human trials, lgF-1
stimulates glucose utilization and provides effective treatment for
acute hyperglycemia. Blood plasma levels of lgf-1 in diabetic
patients were shown to be lower than in non-diabetic groups. After
administrating lgF-1 to diabetic patients, he reported that lgF-1 is
an effective alternative to insulin in stimulating glucose transport in
diabetic muscle (clinical trials have shown a two-fold increase).
CHAPTER SIX

HEALING, WEIGHT LOSS AND ATHLETIC

ENDURANCE

Thanks to the advances in biochemistry in

the last decade, bovine colostrum has been re­
introduced to the world as a potent growth
supplement and immune modulator. With culture
produced Insulin-like Growth Factor (lgF-1) currently
selling in the open market for as much as $800 per
50cc vial, it is little wonder that biotechnology companies are
searching for a means to clone and produce large quantities of the
factors found naturally, only in colostrum. Colostrum contains lgF-1
(insulin-like Growth Factor 1) and TgF-A & B (Transforming Growth
Factor, alpha and beta), and Epithelial Growth Factor (EgF) whose
muscle, nerve, bone, skin, and cartilage repair characteristics are
essential. The many regenerative effects of lgF-1, coupled with
TgF-B, extend to nearly all structural cells of the body. Each new
published study documents the enhancement of DNA and nutrient
uptake mediated by these colostral growth factors, particularly in
muscle and cartilage. Furthermore, lgF-1 promotes the building of
lean muscle tissue, increases protein synthesis and burns fat for
energy.

Without the presence of lgf-1 in the body, our bodies will

not burn fat. lgf-1 is essential in processing fat for energy (the
Krebbs cycle). Without it, the body simply catabolizes (bums) its
own protein during times of fast (diet). It has also been proven that
the number of Fast-glycolic muscle fibers increase in
circumstances of lowered physical activity, decreased protein
intake and lowered lgF-1 levels. This means that our body uses
blood glucose as the primary fuel and will not burn fat.
 It is important that aerobic and weight resistant exercise,
lgF-1 levels and proper nutritional intake all be maintained if we
expect to achieve weight reduction and improved body condition. It
is also important to note that all three are directly related (in
human studies) to increased occurrences of Type II diabetes,
Hyperglycemia, high cholesterol, increased risk of heart disease
and stroke. Normally, our body will produce the needed lgF-1 (if
we are taking care of it or are pre-puberty). There will be
significant reductions in the amount of lgf-1 and other growth
factors brought on by lack of exercise, improper nutrient intake,
toxic exposure and aging. We can replace lgf-1 in our body
naturally, only with Bovine Colostrum.

ATHLETES ARE MORE SUSCEPTIBLE TO

INFECTIOUS ILLNESS

Studies show that a single exhaustive workout is followed

by a temporary immune depression, with a pronounced decrease
in the number of infection fighting lymphocytes (T and NK cells).
These changes can last for several hours. Some athletes develop
chronic debilitating conditions resembling post viral fatigue
syndrome. Studies with animals also prove that exhaustive
exercise increases both susceptibility to and severity of infections.
Colostrum’s many immune factors demonstrate a significant
reduction in the occurrence and severity of numerous types of
infections caused by physical and emotional stress.

TgF AND lg-F-1 FOR HEALING

In 1983, Dr. Sporn and Associates
discovered that bovine colostrum contained a
protein substance that stimulated wound
healing. This substance was broken down
and found to consist of Epithelial Growth
Factor (EgF) which stimulates normal skin
growth, Transforming Growth Factors (TgF), alpha and beta and
Insulin -Like Growth Factor (lgF-1) which stimulates cellular growth
and repair. In 1990, at the University of Arizona, in Tucson,
researchers demonstrated that when growth factors are
administered in combination, they stimulate normal growth and
repair cellular tissue. Cells, so stimulated, will fuse with one
44
another or adjacent muscle fiber, increasing the number of muscle
cells for growth and repair. In 1984, Japanese researchers
discovered that TgF is involved in normal cellular activities such as
embryonic development, cell proliferation and tissue repair. They
also found that it promoted the synthesis and repair of DNA - the
master code of the cell. In 1981, Drs. Gil and Sanchez-Madina
found that bovine colostrum is a rich source of this whole family of
nucleotides, which are so important for normal cell function and
repair. Studies have shown that without the presence of lgF-1, GF
and TgF growth hormones, cells cannot perform their function.
Further studies, at the University of Japan’s Immunology and
Cancer Research Institute, in 1993, found that TgF exerts positive
regulatory effects on the accumulation of our body’s extracellular
matrix proteins. It suppresses production of cytoxic monocytes
(abnormal blood cells) and has a potent inhibiting effect on the
generation of cytoxic T Lymphocytes, NK and LAK cells (abnormal
and toxic immune factors). It also inhibits anchorage dependent
cellular growth of human Osteosarcoma (cancer) cells (a 75%
demonstrated inhibition), is highly anti-inflammatory, is a mediator
of fibrosis (repair tissue formation) and angiogenesis (development
of new blood cells) and promotes healing of wounds and formation
of bones.

lgF-1 can promote muscle growth by itself, something

growth hormone is unable to do. Besides lgF-1, bovine colostrum
also contains a truncated lgF-1 (Des 1-3 lgF-1). This truncated
lgF-1 has been found to be ten times more potent than regular
lgF-1 and is a powerful growth stimulant, even in the absence of
GH.
lgF-1, Insulin and GH increase the uptake of blood
glucose. This ability, demonstrated in vitro years ago, was
confirmed last year by researchers at East Carolina University.
The results, published in the Journal of Diabetes, demonstrate that
lgF-1 can stimulate glucose transport in human muscle.
lgF-1 is an effective treatment for hyperglycemia, slowing the rate
of catabolism following a work out, even under conditions of caloric
deficiency and protein deprivation. Both lgF-1 and GH shift fuel
utilization from carbohydrate to fat.
This means that your body will burn more fat, including fat from
carbohydrate and protein and produce fuel more efficiently. lgF-1
speeds protein synthesis and slows protein catabolism, leading to
an increase in lean muscle mass without a corresponding rise in
adipose (fat) tissue. A prominent researcher, Daniel Shawn, BS,
reported in an article, published in Ironman Magazine, in 1992, :
"there is no other compound in the universe, to date, which can
help you better than lgF-1, not steroids, not biotechnology and it’s
genetically engineered GH, not releasing factors, not even a strict
diet of pure amino acid and glycogen. Plain and simple, lgF-1 is
the end all and the be-all of anabolic peptide growth factors” 3
Other factors found in bovine colostrum are: Epithelial
Growth Factors (EgF) that stimulate skin growth and regeneration,
Fibroblast Growth Factor (FgF) that increase lgF-1 binding by 60-
70%, Gonadotropin-releasing hormone (GnRH) and its associated
peptide (GAP), which stimulate sexual response, Prolactin, Insulin,
and Glycoproteins, which inhibit the digestion of hormonal and
immune factors in the stomach.
Colostrum’s growth factors stimulate rapid healing of
tissues damaged by ulcers, trauma, surgery or disease. These
healing powers benefit muscle, cartilage, bone, epithelial (skin)
cells, nerve cells and immune factors. Colostrum is an excellent
applicant for topical healing. It can be applied directly to minor
cuts, abrasions and burns that have first been cleaned and
disinfected. EGF and other factors, found in colostrum, promise
rejuvenating possibilities in skin cream preparations. Powdered
colostrum can be applied directly to gums in cases of gingivitis,
sensitive teeth and mouth sores with excellent results. Internally
and externally, colostrum heals, protects and builds.
A WORD OF CAUTION
Colostrum is the only natural source of these vital growth
and healing factors. Bovine colostrum has been shown, through
hundreds of years of human use and clinical studies, to be
completely safe, with no drug interactions or side effects at any
level of ingestion.

Growth factors, IgF and GH, are two of the most researched
hormones, with thousands of published reports. Isolated and
reproduced lgF-1 and GH, currently available, outside the US, in anti­
aging clinics and sold underground to athletes, pose a danger of
serious illness and life threatening side-effects. The public outcry
against giving growth hormones to dairy cows, to increase milk
production, comes from evidence supported by clinical research that
has shown that isolated forms of GH and lgF-1 stimulate abnormal
growth of cellular structures and are considered possible carcinogens.
Colostrum, nature's perfect first food for life, cannot be laboratory
reproduced and is the natural, safe source of essential growth
factors and immune factors necessary for our survival.
4 8
CHAPTER SEVEN
FOUNTAIN OF YOUTH
The New England Journal of Medicine (the
most prestigious medical journal in the world) reported
that the most effective means to stop or slow the aging
process would be to replace the hormonal factors that
cause us to grow normal cellular structures in the body.
After maturity (between the ages of 16-20), the level of
growth hormone that our body naturally produces
dwindles. We notice this as gravity, unmercifully, takes
its toll. Our bodies lose muscle tone and elasticity of
the skin, causing us to sag and wrinkle. We lose bone mass and
shrink, while our hands, feet, nose and ears get larger. We’d all do
almost anything to stop this aging process but we may want to
think twice before we consider isolated hormone replacement
therapy. Most hormonal replacements are synthesized from plant
sources and are not identical to the hormones made by the body.
Synthesized and isolated hormones can produce body imbalances
and side effects that can be life threatening!
There is another answer. A natural answer. Colostrum’s
perfectly balanced combination of immune and growth factors,
administered in human clinical trials with aged subjects, safely
increases lgF-1 to pre-puberty levels, producing increased muscle
weight and strength. lgF-1 and GH in colostrum also has been
shown to tone muscles, melt body fat, return elasticity to the skin
and increase bone density. Colostrum, life’s first food, has given
those of us that are growing older, real hope that there may be a
Fountain of Youth after all!
Everything in life springs forth from DNA - flesh, bones,
hormones, nervous system, a baby's first word, the euphoria that
comes with first love, the ability to learn to speak a foreign
language. All of this originates from DNA. This silent intelligence of
life, DNA, attracts the chemicals it needs to form new DNA which is
an essential part of cell division. DNA is also able to manufacture
RNA, which is nearly identical to DNA and participates as its
active counterpart. RNA (the active intelligence) is the traveler sent
to produce the proteins needed to build and repair the body. Dr.
Benjamin Frank, whose research on youth and aging, showed RNA
to be one of our most critical anti-aging factors. His research
showed that lgF-1 (found naturally in colostrum) is one of the only
substances known to stimulate the growth and repair of these key
nucleic acids, DNA and RNA.
Colostrum has been shown to help maintain blood glucose
levels to serve the brain. Also, lgF-1 and GF, some of the smallest
particles known, have been shown to cross the blood brain barrier
to help with nerve synapses in the brain, enhancing mental acuity
and increasing serotonin levels, to brighten our moods. And just
possibly, as we age, this might be one of the most important
reasons to take a serious look at colostrum.
The aging process is accelerated as our natural immune
system is depleted. Colostrum can help reverse this by
strengthening our immune system and replacing the actual immune
factors that our immune system needs to keep us disease free.
Colostrum is unique, in all the world, for its ability to support our body’s
basic intelligence, DNA and RNA, in promoting normal cell growth and
tissue repair. We can now understand why colostrum has been
heralded as the ultimate anti-aging food supplement.

50
EFFECTIVE USE
COLOSTRUM IS A FOOD, NOT A DRUG OR MEDICINE
COLOSTRUM IS SAFE, NON TOXIC, NON ALLERGENIC
AND NO SIDE EFFECTS

Bovine Colostrum is safe, non-toxic and can be consumed

in any quantity without side-effects or drug interactions. It contains
special enzymes that prevent its immune and growth factors from
being digested. A recent article written by Robert Preston, ND,
president of the International Institute of Nutritional Research,
states, “Bovine colostrum is safe. Colostrum contains an
unprecedented combination of nutritional factors with which to
fortify the immune system. It is so harmless, it has been prepared
by Nature as the first food for infants, intended as their total diet for
the first 24 hours.” He further states, "it would be hard to imagine
any nutritional substance more natural or beneficial than
colostrum. It is safe for internal consumption by children, adults
and animals.“ 4
How much should be taken and how often? You should
take enough colostrum to obtain results. If you’re not seeing
results with colostrum, you are not taking enough. I have
found that adults should begin with a minimum of 3,000 mg. per
day. It can then be lessened to a maintenance level as long as it
continues to produce results. Colostrum has a sixteen hour half
life. It should be taken twice a day on an empty stomach with a full
glass of water. Colostrum’s benefits are cumulative. The longer
and more consistent the use, the greater the benefits.

Most people feel better right away; some go through a

rough "healing crisis” reporting flu-like symptoms such as fatigue,
nausea, diarrhea, headache, coughing up phlegm, skin rashes and
low grade fever. This usually lasts only a couple of days. The body
is ridding itself of long-accumulated toxins, locked in the body’s
tissues and fat deposits that have suppressed the immune system
and encouraged disease. Do no decrease use at this time.
In fact, this might be a good time to temporarily increase the
dose. Most people with disease are felling so bad anyway that the
knowledge that their body is healing can pull them through the
hard times.
Colostrum is not just for adults. I’ve seen remarkable
results with babies and children. Colostrum’s test is in the
undeniable health of children who received colostrum and breast
milk from their mothers. These children experience less illness,
increased mental acuity and have stronger, more vibrant growth.
Yet, even today, children face circumstances where it has not been
possible to provide them with this wonderful natural healer.
Premature babies and newborns, who did not get colostrum, can
greatly benefit from the symbiotic bovine source.
Children’s age and weight need to be considered when
administering colostrum. Continual use of colostrum for children is
unnecessary since they naturally produce (within their bodies)
many of colostrum’s components. Its use with children should be
held for those times that colds, flu, viral or bacterial invasion or
disease may be mitigated with it’s use or when antibiotics or drugs
have compromised their body’s immune functions.
We can't forget our pets. Veterinary use of bovine
colostrum with aging and/or ailing animals (mammals) has proven
to be very beneficial. Its ability to stop disease is well documented
and may even be more effective than with humans.
I feel that it is important for each one of us to take
responsibility for our own health. If you are convinced by
claims, testimonials or even research that a product will stop
disease, you must make certain that there is also supporting
research that the product does not destroy body tissue,
interact with other drugs or supplements or create harmful
side-effects in the process.
CONCLUSION
Colostrum, known for its powerful healing factors, gives us
a natural and safe answer for optimal health. Medical research
reports, presented by doctors and scientists from major research
centers, hospitals and universities around the world, state that the
presence of such a wide spectrum of immunoglobulins, antibodies
and accessory immune factors, found in colostrum, offer
tremendous possibilities in the prevention of and recovery from
illness. Colostrum’s immune factors not only boost the underactive
immune system but work toward regulating the overactive immune
system (allergies and auto-immune disease). Colostrum’s growth
factors favor tissue repair bringing many regenerative anti-aging
benefits. These growth factors help build lean muscle tissue, bum
fat for energy, increase protein synthesis, build and repair RNA
and DNA, increase uptake of glucose and regenerate nerve, skin,
bone and cartilage tissue.
Colostrum’s timely rediscovery, with its great potential to
fight disease, improve quality of life and increase longevity is
unprecedented. It can not be duplicated in a scientific laboratory.
Its unique combination of immune and growth factors are only
possible from nature. Colostrum is life’s first food and it is perfect.

5 3
54
TESTIMONIALS
Reports from people using bovine
colostrum range from weight loss,
feelings of wonderful well-being, dramatic
reductions and elimination of pain and
symptoms of disease, accelerated
healing with surgeries, wounds and
broken bones, elimination of colds and
flu, accelerated physical strength and endurance to near
miraculous cures. The following are just a few excerpts from some
of the heartfelt stories that keep pouring in.

“I feel like I have truly found a miracle in my life. I have

suffered from multiple sclerosis for seven years. After taking
colostrum for only a couple of months (three teaspoons a day), all
MS symptoms have left my body (dizziness, weakness and fatigue,
eye problems, burning sensation in my feet). I am able to walk
without a limp and climb stairs without the aid of a railing. I cannot
say enough good things about this miraculous food.”
Bonnie; Ogden, Utah

“My doctor’s diagnosis was that I had Epstein Barr Virus

and he recommended a six month disability. After taking colostrum
for a month, I found a notable improvement in my energy level, an
ability to sleep, relief from muscle aches and pains and I was able
to begin exercising. I am recommending colostrum to all of my
friends and family.”
Natalie; Salt Lake City, Utah

“I severely burned my wrist on an engine block. I was told

that it would take at least a month to heal and would probably
leave an ugly scar. With colostrum, it was completely healed,
without scarring, in one week.” Howard; Bethesda, Maryland

“I was diagnosed with Polymyalgia Rheumatica (disease

where inflamed blood vessels affect the joints and muscles).
Colostrum has not only helped me physically but also mentally and
spiritually. I am no longer depressed because I am getting better
and better. My husband appreciates the “new me”. I would
recommend colostrum very highly for those who want the finest
quality of life.”
Rhoda; Clearwater, Florida
 "I am a seventy year old man who, this last year, has gone
through a devastating personal experience that led to severe
depression. For ten months, my doctor prescribed numerous
antidepressant drugs that didn’t help at all. After taking colostrum
for two months, my depression lifted. I also had a total knee
replacement two weeks ago. I had the other knee replaced a year
ago and it took forever to heal. To everyone’s disbelief, ten days
after my surgery, I was out dancing. My muscles are more defined
and my stomach is noticeably flatter. My blood pressure has
dropped from 145/85 to 120/70 and my pulse has gone from 83 to
7 0 .1have been able to come off heart medication.”
Bill; Holladay, Utah

"I have had hives internally and externally that even the
strongest medication hasn’t helped. Within days of taking
colostrum, 95% of my symptoms were gone. For the first time in
years, I am able to wear clothes comfortably, sleep, go to work, eat
normal foods, and cuddle with my wife. I have more energy and I’m
less moody. My wife thinks she married a new man. I have my life
back - plain and simple. There are no words to express how
incredible this is and what it means to me.”
Warren; Murray, Utah

“I have been troubled with very painful bursitis in both of

my hips for the last three years. Nighttime was the worst because
any movement would waken me to pain. I have had physical
therapy treatments regularly to obtain some relief. Because I was
so miserable, I decided to try the colostrum. At first, I didn’t think
that it was helping me but after three weeks, I was pain free.
I have always been quite a skeptic, so I was truly surprised and
very happy."
Janet; Cottonwood, Utah

“Years ago, I broke my right shoulder twice and my left

shoulder once. With any lifting, I would dislocate my shoulders.
Colostrum has given me noticeable upper muscular strength and I
no longer have a problem with lifting. I had orthoscopic knee
surgery shortly after I started taking colostrum. They had to smooth
the knee cap and repair cartilage. I was back at work and climbing
stairs two hours after surgery. My work brings me in close contact
with over forty men on a daily basis. I am the only one that hasn't
been sick this winter. I’ve never felt better and I guess it shows
because everyone tells me that I look better than I have for year."
Ken; Salt Lake City, Utah
 “Since having breast cancer in 1991, I've had a difficult
time losing weight. After only one month of taking colostrum, I lost
seven pounds, 3 1/2 inches off my waist and an inch off my bust
and hips.” Georgia; Fairbanks, Alaska

“I was getting worried because my eyes wouldn’t focus for

distance (everything was blurry) after reading the newspaper. Day
by day, this problem seemed to get worse. Thank God for
colostrum. It cleared up the problem in one week.”
Judy; Sandy, Utah

“I was diagnosed with Blepharitis (inflammation of the

eyelids). Areas on my face became red, swollen and itched.
Steroid creams did not help but with colostrum, my problem has
completely cleared up.” Pat; Salt Lake City, Utah

"I've taken colostrum for just one month and my stomach

and intestinal tract has never felt better (no more bloating and
indigestion). Now I can eat anything I dam well please. I've noticed
that the flu bug that everyone is getting is passing me by.”
Robert; Salt Lake City, Utah

“Because of colostrum, my vision has improved, my

memory seems better, my gums have stopped bleeding, I have
more energy and my muscles are firmer. It’s as though I’ve been
working out at the gym for months. For the first time, my allergies
are 90% better. I just can’t believe it when I look in the mirror. I
look like I’ve had a facelift. Incredible! My fingernails and hair are
healthy (thicker and grows faster). Colostrum is truly a miracle in
my life. I am so grateful!” Deanna; Palmer, Alaska

“Nothing would touch my warts. If they were removed,

more would come back in their place. After taking colostrum, I have
no more warts.” lim ko; Germany (age 11)

“I’ve taken two inches off my waist and increased my chest

1 1/2” after a couple of months of taking colostrum. My skin is
softer with less noticeable wrinkles. My age spots have
disappeared. If I feel a cold or flu coming on, I take a big spoonful
of colostrum and the symptoms are gone in an hour."
Alan; Holladay, Utah
 “I suffer from Multiple Sclerosis. On the regular dose of
colostrum, I noticed that I felt stronger and my fatigue was easing
up. I increased my dose and after one month, 95% of my
symptoms are gone. Incredible difference.”

Lisa; Ashley, Pennsylvania

"For the last three years, I have suffered from sinus pain.
Colostrum cleared my sinuses. I ran out and the problem was
back. I started the colostrum again and will not go off of it again.
Besides relief from sinus pain, colostrum keeps me from going into
the doldrums, gives me constant energy and an overall sense of
well-being. My brother thought that he was coming down with a
cold on two occasions. A couple of hours after taking colostrum, he
felt great.”
Kirk; Holladay, Utah

“I am a non insulin diabetic. I’ve been taking colostrum for

just over a month. I went to my doctor for my routine tests. My
blood sugar levels had dramatically improved for the first time. This
colostrum really works.”
Pete; Holladay, Utah

“I haven’t been able to eat solid foods for three years

because I have advanced Sclera Derma (one of the most
debilitating of the autoimmune diseases). All nourishment had to
be taken in liquid form. After just one week of taking colostrum, I
was able to go out to dinner with my family and eat a whole
hamburger. There are no words to express what colostrum means
for myself and my family.”
Sydney; Concord, California
 BIBLIOGRAPHY
IMMUNE FACTORS: RESEARCH RELATED TO

Sabin, Albert B. 1950, Journal of Diseases of Children, 80, p.866;

'Antipoliomylitic Substance in milk from Human Beings and Certain
Cows’; As early as 1950 Dr. Albert Sabin, a discoverer of polio
vaccine, reported an antipolio substance in the milk of cows,
despite the fact that cows do not get poliomyelitis.

Sabin, Albert B. et. al. 1962, Pediatrics, 29, pp. 105-115.

'Antipoliomylitic activity of human and bovine Colostrum and milk’;
Dr. Sabin isolated antipolio antibodies in bovine colostrum.
(Bovine colostrum was used in oral administration
successfully. Antibodies were isolated and a successful
vaccine prepared.

Samson, R. R. et. al., Immunology, 1975,Vol 38, No 2, 291-296.

Dr. Samson and associates found colostrum was 21 times richer in
Vitamin B-12 than milk. Research in 1975 confirmed that adequate
B 12 in body doubles body’s immune systems ability to fight
disease.

Ho, Lawton, 1978 Human Colostral Cells, Journal, of Pediatrics

Vol. 93, No. 6 pp 910-15 in hospital use showed that colostrum
Leukocytes are effective against E. Coli and the yeast Candida
albicans.
Lawton, et. al., 1979, Archives of Disease in Childhood, 54,
pp. 127-130; ‘Interferon Synthesis by Human Colostral Leukocytes’;
Exposure of Colostrum leukocytes to certain mitogens
stimulated production of interferon, the substance that slows
or prevents viral growth.

Bouda et. al.,1980, Acta Veterinaria Brno. Vol. 49 No’s 1-2 pp 53-
58. ‘Vitamins E and C in the blood plasma of Cows’; Vitamin E is
2.5 times greater in bovine colostrum than in milk. It helps protect
the Vitamin A and other ingredients from oxidation. 'Vitamin A and
Carotene Metabolism in Cows’ pp 45-52; Vitamin A in bovine
colostrum is ten times the amount in serum. Vitamin A shown to
restore and revitalize the thymus gland the master gland of the
immune system.
Palmer, E. L. et. al., 1980, Journal of Medical Virology. 5 pp 123-
129. ‘Antiviral Activity of Colostrum and Serum Immunoglobulins A
and G.’; Colostrum has an enteric secretory virus antibody that
acts against viral invaders. A wide range of antiviral factors were
acknowledged to be present in colostrum. This research was done
at the US Government’s Center for Disease Control in Atlanta,
Georgia.

Dluholucky, S. et. al.,1980, Archives of Disease in Childhood, 55,

pp 458-460; 1980; ‘Antimicrobial activity of colostrum after the
administration of inactive Escherichia Coli oral vaccine to
expectant mothers’; Mothers developed immune factors that
develop on mucosal sources that enter blood serum and
concentrate in expectant mothers’ mammary glands. Describes
how colostrum may develop immunities.

Morris, J. A. et. al., 1980, Journal of Medical Microbiology Vol. 13

No 2 pp 265-271. ‘Passive Protection of Lambs Against
Enteropathogenic Escherichia Coli’; Mother sheep and cows given
doses of E. coli orally developed antibodies for E. coli in their
colostrum. When nursing offspring were then dosed with E. coli,
immune factors from the mothers’ colostrum prevented the E. coli
from attaching to the bowel wall and protection resulted.

Majundar et. al., 1982, Infection and Immunology, Vol. 36 No 3 pp.

962-965;: ‘Protective Properties of Anticholera Antibodies in
Human Colostrum’; Mothers in India exposed to cholera passed
on protective antibodies to their newborn which prevented them
from getting the disease.
McClead, Richard, Et. Al., 1982, Pediatric Research, Vol. 6 No 4 p
227, 'Resistance of Bovine Anti-Cholera Toxin IgG I (Anti-CT) to in
Vitro and In-Vivo Proteolysis’; Colostrum from cows exposed to
cholera contained IgG antibodies which protected against that
type of cholera.

Theodore, Christine, Et. Al., 1982, Raven Press, NY: ‘Immunologic

Aspects of Colostrum and Milk: Development of Antibody
Response to Respiratory Syncytial Virus (RSV) and Bovine
Serum Albumin in the Human and Rabbit mammary Gland’;
People and animals exposed to RSV virus, often responsible for
Bronchitis and Pneumonia, developed IgA and IgG
(Immunoglobulin) antibodies against this virus in their
colostrum.
Cruz, et. al., 1983, Annals of NY Academy of Sciences, 409 pp.
808-809: 'Specific Immune Response in Human Milk To Oral
Immunization With Food Protein’; Immune factors from the mothers
blood serum are added to mammary secretions.

Ebina, et. al., 1983, The Lancet, Vol. 29 No 2 pp. 1029-1030:

'Prevention of Rotavirus Infection By Cow Colostrum Containing
Antibody Against Human Rotavirus’; Japanese researchers
exposed cattle to oral doses of rotavirus which causes severe
diarrhea and bowel inflammation in humans. Colostrum from
these cows contained antibodies which, when fed to humans,
prevented them from getting Rotavirus.

Ogra, Lesonsky, Fishout, Research, 1983, State University of NY

at Buffalo: Colostrum provided specific antibody reactivity to the
bacteria, viruses and yeasts responsible for the following
conditions: Appendicitis, Aseptic or Viral Meningitis, Bronchitis,
Bronchia or Viral Pneumonia, Candida Albicans, Chicken Pox,
Cholera, Diarrhea, Dysentery, Diphtheria, Gastroenteritis,
Japanese B Encephalitis, Mucus Membrane Infections,
Parathyroidism, Pneumonia, Polio, Septicemia (blood poisoning),
Tetanus, Typhoid, Viral Myelitis, and Whooping cough.”

Kim, et. al., 1985, Journal of Infectious Diseases, Vol. 150, No 1

pp. 57-61: ‘In Vitro and In-Vivo Neutralizing Activity of Human
Colostrum and milk Against Purified Toxins A & B of Clostridium
Difficile’; substances from colostrum neutralized the two main
toxins of the infectious Clostridium bacteria which cause
illness.

Lie, Syed, Animal Genetics, 1986, V. 17 pp 47-59: Some

properties of the lysozymes in colostrum from cows: “High
bacteriolytic activity, fully expressed in colostrum, heat stable
in acidic pH.

Acosta-Altamirano, et. al., 1987, Advances in Experimental

Medicine and Biology, 216B pp. 1347-52: 'Anti-amebic Properties
of Human Colostrum’; Colostrum effective against amebic
invaders.

Buescher, Mcllheran, 1988, Pediatric Research, Vol. 24 No 1 pp.

14-19: ‘Antioxidant Properties of Colostrum’; Colostrum found to
contain numerous powerful, naturally occurring, antioxidants.
Zhang, Iguchi, Mochizuki, et. al, 1990, Proc. Soc. Exp. Biol. Med.
Jul.; 194(3): 270-3. Gonadotropin-releasing hormone (GnRH)
and it’s associated peptide (GAP) found in bovine colostrum
plays an important role in the release of Cytokines (Immune
messengers used to elevate immune activity, they also serve
both ANTI-VIRAL AND ANTI-TUMOR functions).

Shortridge, Lawton, Choi, 1990, Journal of Trop. Pediatric. APR;

36(2): 94-5 Reported: A. Incidence of infection and gastrointestinal
illness markedly reduced in breast fed babies. B. Colostrum
contains Non Specific Inhibitors (NSI’s): factors that are inhibitory
for a wide range of respiratory illness notably influenza viruses.
C. Colostrum specifically cited for its unique effectiveness
against potential deadly outbreaks of (new) Asian flu viruses
that emerge from animal/human mutations.

Tacket, Binion, Bostwick, et. al. ,Amer. Jour of Trop Med Hyg,
Sept. 1992 V47(3) p276-83: ‘Efficacy of Bovine immunoglobulin
concentrate in preventing illness’; Human trial with hyper immune
immunoglobulin administered orally with sodium bicarbonate.
Conclusion: Orally administered bovine immunoglobulin
protects against shigellosis and may be useful in preventing
shigellosis among travelers”.

Science, Vol. 257 Jul. 10, 1992: Transferred immune cells help
fight viral infections’; Cytomegalovirus (CMV) cause of fatal
pneumonia in bone morrow patients reduced with introduction of
specific immune cells via administration of bovine colostrum.

Watson, Fransis, Ballard, 1992, Journal of Diary Research Aug.

59(3): 369-80 'Bovine Colostrum cell-growth factors as well as
immunomodulatory factors are able to regulate IgE response in
heterologous species’; Immune regulatory factors are
transferable to human and other species

Applegate, Runners World, June 1992, V27 p22 Protein Power:

“Protein depletion weakens the immune system and causes
irritability.’’

Berl, Munch, etal. 1992 Jul. 1; 105(7) pp219-24 ’Bovine colostrum

and protection of young animals’; Calves without colostrum died in
90% of cases. Feeding commercially prepared colostrum can
provide immediate compensation. The application of vaccine(s)
directly into the mammary gland at ablactation provokes
6 2
specific IgA and IgM antibodies which are normally not
channeled from the blood system of the mother into the
colostrum. This kind of immunization may become more and
more important”.

Hernell, Olle At the University of Ulmea, Sweden 1995, Science,

Apr. pp 231 reported findings that Glycoproteins in bovine
colostrum inhibited attachment of the Helicobactor Pylori
bacteria believed that causes stomach ulcers, and that
colostrum contains significant amounts of interlukin-10, a
strong inflammation inhibitory agent significant in reducing
inflammation in arthritic joints and injury areas.

COLOSTRUM’S SURVIVES ADULT HUMAN DIGESTIVE TRACT

AND WORKS ON MUCOSAL SURFACES:

Pineo, A. et. al. 1975 Biochemical Biophysiology Acta

(Amsterdam.) 379: 201-206. Research by Drs. Pineo, Ortego,
and Uriel in 1975 discovered a special Glycoprotein in cow
colostrum. They found it had “Protease Inhibitor Activity” that
was extremely effective at protecting the immune and growth
factors in colostrum from destruction by digestive acids
pancreatic enzymes in the adult human stomach.

Sandholm et. al., Acta Veterinaria Scandinavica, 1980, Vol. 20 No

4 pp 469-476. ‘Colostral Trypsin-Inhibitor Capacity in Different
Animal Species’; Bovine colostrum was found to contain a
powerful trypsin-inhibitor which protects colostrum
immunoglobulins from digestion. Demonstrated that
colostrum from cows richer in immune factors and inhibitor
than colostrum from humans.

Von Fellenberg, R. and Hoeber, 1980, Schweiz. Arch. Tierheilkd.

Vol. 122 No 3 pp 159-168. ‘Multiple Protease Inhibitors in
Colostrum and In Bovine Udder Tissue and their Possible
Significance’; Protease inhibitors in colostrum shut down the
digestive enzymes that would normally digest proteins such
as the immunoglobulins, allowing them to remain active as
they pass into the bowel.

The Immunology of Infant Feeding, 1980, Plenum Press, NY, pp

13-20, Swarbrick, E. T. et. al.,. The Handling of Ingested
Antigens': Dr. Swarbrick discovered that during the first 24-36
hours of a newborn’s life the bowel wall has a number of large
open pores through which big immunoactive molecules from
colostrum enter the system. Pages 55-61; Dr. David Tyrell; ‘Breast
Feeding and Virus Infections’; “The major benefit of immune
factors from colostrum was shown to be their protective
activity in the intestine on the walls of the bowel, and
bronchioles, (mucosal surfaces). Conclusion: People of all
ages may benefit from colostrum”.

Hanson, et. al., Annals of NY Academy of Sciences, 409,

15ff: ‘Mucosal Immunity’: The immune system produces
immunoglobulins, antibodies, leukocytes, macrophages, interferon
and other factors for defending the body. Immune factors from
specialized cell groups in the bronchioles and bowel travel away
from their sources to coat the passages of the lungs and bowels
and destroy antigens, allergens and pathogens. Immune factors
from colostrum other than immunoglobulins blocked
attachment of many types of bacteria to Mucus membranes.
Oligosaccharides (big sugar molecules) from colostrum
blocked attachment of Streptococcus pneumonococci, a
major cause of lung inflammations and middle ear infections.

Klapper, D. G., et. al., 1983, Endocrinology, 112 (6) 2215-7. pp.
13-18: Oiigo and polysaccharides in colostrum bind many
types of bacteria and prevent them from attaching to or
entering the body though the mucal membranes.

Eldrige, et. al. 1983, Annals of NY Academy of Sciences, 409 pp.

819-821. ‘Peyer’s Patches accessory Cells Bear 1-1’; Groups of
cells in the mucosal of the intestinal tract, known as Peyer’s
patches produce and absorb immune factors.

Bouda, et. al., 1987, Vetehnari Medicina, Vol. 32 No 3 pp. 135-44:

‘Trypsin Inhibitor Activity in the Colostrum of Cows’: Greatest
Trypsin Activity was in the colostrum of the first milking after
calving, (inhibitor effective in neutralizing digestive acids and
enzymes in human digestive system to allow colostrum to
reach intestinal area)

Preston, R., 1987, International Institute of Nutritional Research:

‘Bovine Colostrum: Human consumption: Efficacy and
effects’: Found to be safe, effective via oral administration, no
known contradictions or overdoses.
Ogram, Pearay, et. al., 1983, Annals of NY Academy of Sciences,
409, pp 82-92: ‘Colostrum Derived Immunity and Maternal
Neonatal Interaction’; Peyer’s patches are found throughout the
intestinal tract and groups of immunoactive cells like them are
found in the bronchial mucosal. Both the intestinal and bronchial
immunoactive cell groups respond to allergens, antigens and
pathogens by neutralizing or destroying them. In newborns, these
special cell groups are not immediately operative but protection is
provided by a variety of immune factors from the mother's
colostrum. Antibodies found in colostrum protect against E. coli,
Salmonella, Shigella, V. cholera, Bacteriodes Fragilis,
Streptococcus Pneumoniae, Bordtella Petussis, Clostridium
diphtheria, Clostridium Tetani, Streptococcus mutans and Candida
Albicans.

Waldman, et. al., 1983, Annals of NY Academic Science, Vol. 409,

510-515: Reported the intestinal tract is lined with mucus
membranes. Researchers at West Virginia University School of
Medicine and Pharmacy stated: “ Most infectious diseases enter
the body through or remain localized on mucosal surfaces."
Waldman stated: “that this means in order to be healthy, we must
be able to combat disease causing organisms where most of them
attack us; which is on the mucus membranes of the intestinal
tract.” (this is where colostrum does most of its work).

Sandholm, et al., Acta Vet. Scand. 1979, V 20 p 469-476 Colostral

Trypsin-inhibitor capacity in cows colostrum’; Colostrum of cows
showed high antitrypsic activity at parturition, decreasing to
1/100th in one week. The role of antitrypsin in protecting
immunoglobulins from proteolytic damage during passive transfer
of immunity is obvious. Trypsin inhibitor in cows colostrum is a
Glycoprotein. Human colostrum does not contain an antitrypsis
inhibitor because most immunities are passed through the placenta
prior to birth.

Ulcova-Gallova, Fialova, Krauz, 1994, Clinical Study: Cas Lek.

Cesk. May 2, Vol. 133(9) pp. 275-6. Reported that: A.
Immunofactors present in bovine colostrum are: IgG, IgM, IgA,
SlgA, C3, C4, Orosormucoid, Prealbumin, Alpha 1- antitrypsin,
Alpha-1 fetoprotein, Alpha-2-Macroglobulin, Alpha 2- AP
Glycoprotein, and, IgE. B. An important immunological liquid
with proven bacteriostatic and viral inhibitory activity
preventing penetration of pathogenic microorganisms and
absorption of potential allergens into the digestive tract.
6 5
Service, Science, Sept. 9, 1994 v 265 p 1522-4: Research News:
'Triggering the First line of Defense’; Vaccines that activate the
mucosal immunity, the bodies first chance to ward off infection, are
hard to come by. Situation changing, new vaccines are needle
free. Mucosal surfaces turn out 70% of our body’s antibodies.
Has been virtually ignored. Mucosal system most important
area to concentrate attention in prevention of disease. New
vaccines developed to be delivered orally. IgA very effective in
picking up invaders before they gain entry. Studies prove that
vaccines made with similar bugs that infects animal can
confer protection to humans against challenges.

Science News: Vol. 133 pp. 196, 1994; ‘Colostrum and breast
milk (from cows, sheep and humans) stimulates babies own
immune systems’; as yet unidentified proteins speed the
maturation of cultured B lymphocytes (a type of white blood
cell) and prime them for production of antibodies says:
Michael Julius Of McGill University, Montreal.

IMMUNOGLOBULINS: ANTI-VIRAL, ANTI-BACTERIAL, ANTI­

YEAST, ANTI-TOXIN

Bruce, C. E. 1969 Natural History, , Feb.; Dr. C. E. Bruce

demonstrates that human colostrum contains only 2% IgG (the
body’s most important immunoglobulin) while cow colostrum
contained a phenomenal up to 40 times that amount.

Brandtzaeg, Per, 1983, Annals of New York Academy of Sciences,

Vol. 409 pp. 353-378; The Secretory Immune System of Lactating
Human Mammary Glands Compared with other Exocrine Organs’;
Immune factors present in the mother are transmitted to the infant
in colostrum and breast milk until its immune system is operative,
Immunoglobulins are able to neutralize the most harmful
bacteria, viruses, and yeasts.
Harper, H. A. et. al., 1977, Review of Physiology Chemistry (Lang
Medical Pub. Los Gatos, Ca.). ‘Analysis of immunoglobulins and
how they work in the defense of disease’; Showed the bodies
key immunoglobulins: IgG, IgM, IgA, and Secretory IgA contain “Y”
shaped proteins with special adaptive sites on the ends of their
arms. These sites are very effective at neutralizing different types
of bacteria, viruses, and yeast. When the arms, or the FAB portion,
are released by pepsin or trypsin, they are freely assimilated by
the tissues and become an important part of the body’s immune
system. Sic: (In 1983 it was discovered that (bovine) colostrum
contained all four key immunoglobulins and that they were not
species specific).

McClead, R. et. al, 1979, Pediatrics Research, Vol., 13 No 4 2 of 2,

464. Human clinical study completed using immunoglobulins
and antibodies from cow colostrum proving its effectiveness
against disease-causing bacteria. Presented in 1979 by and
Dr. R. McClead and associates at the 89th annual meeting of
the American Pediatric Society. It was demonstrated that
immune factors in cow colostrum, when taken orally, are
effective against disease-causing organisms in the intestinal
tract. Their report concludes, “Ingestion of bovine Colostrum
immunoglobulins may be a new method of providing passive
immunoprotection against a host of gut-associated antigens.”

Khazenson, L. B., 1980, Microbial & Epidemial Immunobiology No

9 101-106; In 1980 Dr. L. B. Khazenson and assoc.’s
completed a study on human volunteers in which cow
colostrum was taken orally. Samples of their digestive tract
demonstrated that the immune factors were effective in
providing protection. They concluded: “ The Preservation of
the biological activity of IgG (immunoglobulin) in the digestive
secretions of adults receiving bovine immune colostrum orally
indicates passive enteral (intestinal) immunization for the
prevention and treatment of acute intestinal diseases.”

Ushijima et. al., Dept, of Enteroviruses, Japanese National Health

Institute, Mar, 1990 V64(3)p 274-9; ‘Immunoglobulin components
and anti viral activities in bovine colostrum’; IgG, IgM, IgA were
found in bovine colostrum, anti-human adenovirus antibody was
not found. Oral treatment rotavirus gastroenteritis found to be
effective. (Rotavirus is the leading cause of diarrhea in world)
Heaton, Arch of Disease in Childhood, 1990; 65:813;
'Cryptosporidiosis and acute Leukemia: Paper at 6th annual Asian
Pediatric Conference’; Treatment of 3 year old with acute
Cryptosporidia caused diarrhea. Bovine colostrum 100 ml 3 x daily
in form of milkshake. Within two weeks symptoms alleviated.
Cryptosporidia tests negative. Bovine colostrum very rich source of
immunoglobulins. Pooled colostrum from nonimmunized cows
provides an effective method of controlling symptoms in
immunodeficient patients. Immunoglobulin concentrated may
provide an effective, convenient method by which immunology
can be administered.

Bocci, Bremen, Corradeschi, Luzzi and Paulesu, 1991, Journal

Biology Regul. Homeost. Agents Oct-Dec 5(4): 121-4.
REPORTED: A. Immunoglobulins cannot be received through
the placenta. B. Colostrum has a well acknowledged crucial
value for the survival of animal species. C. Presence of 4
Cytokines verified in bovine colostrum: Interlukin 1 & 6, tumor
necrosis factor, and interferon gamma. D. Exert an Important
immunostimulatory role particularly on the oropharyngeal-
associated lymphoid tissue. E. Administration can provide
benefits in aged or immunodeficient people. F. Nature has
used the oral route for the development of the immune system
since the origin of mammals (safe and effective). G. Oral
administration of Immunofactors is very simple, inexpensive,
free of side effects and may vastly beneficial in veterinary and
HUMAN medicine to correct Immunodeficiency.

Jage, Kampmann, Kolb, et. al., 1992, Clin. Investigation Jul.;

70(7): 588-94 Reported: A. Immunoglobulins from bovine
colostrum (lactobin biotest, Dreieich, FRG) contain high titers
of antibodies against a wide range of bacterial, viral and
protozoa pathogens, as well as against various bacterial
toxins. B. Lactobin quite resistant to gastric acids. C.
Effective in the treatment of intestinal opportunistic infections
associated with HIV and other immunosuppressed disease.

Kaufman, American Health, May 1992, p33; 'Virus Hunter’ (Paul

Cheney) : “Paul Cheney known as Dr. Chronic Fatigue says
CFS is an immune system disease caused by a retrovirus”.
’Immnoglobin to Prevent Nosocomial Infections’; New England
Journal of Medicine, July 23, 1992, Vol. 327 No 4 p 269.
Immunoglobulin from bovine colostrum effective in reducing
and preventing (viral and bacterial) infections in immune
deficient subjects: bone marrow recipients, premature babies,
AIDS, etc. Problem: obtaining high and consistent levels of
functional antibodies though donor selection. Could improve
through pooled selection, selective donor immunization, and
addition of monoclonal antibodies.

Jochims, Kaup and Drommer, 1994, Res. Vet. Science Sept. Vol.
57(2) pp. 146-151 Reports the absorption of colostral IgG
(immunoglobulin) by small intestine enterocytes in adult
human subjects.

Quigley, Martin, et. al., J Diary Sci., Jan 1994;Vol77(1):264-9

Immunoglobulin concentration in cows colostrum: IgG 65.8 IgM 2.4
and IgA 1.7 g/l.

Science News 1994, vol. 133 p 196; 'Breast Milk stimulates

immunity’; Researchers reporting evidence that colostrum
stimulates babies own immune systems. Speeds maturation of
B Lymphocytes (a type of white blood cell) and primes them
for production of antibodies, according to M. Julius of McGill
University, Montreal. March 1 Journal of Immunology reported
sheep’s colostrum enhances growth and differentiation of
cultured white blood cells. Similar activity in cow and human
colostrum can also activate macrophages.

Petschow and Talbott, 1994, Journal of Pediatric

Gastroenterologic Nutrition. Aug.; 19(2) pp. 228-235, ‘Bovine
colostrum immunoglobulin concentrates proposed for
incurring passive immunity against various enteric
pathogens’; Reports on specific bovine colostrum viral
immunofactors for rotavirus partially reduced by gastric acid.
Suggest reduction of gastric acid and pancreatic trypsin would
enhance immunoprophylaxis (effectiveness).

Dwyer, New England journal of Medicine, Jan 9, 1992, V326

p107(10); ‘Manipulating the immune System with Immunoglobulin’;
Reports that: Immunoglobulin has been used to successfully
treat: Thrombocytopenia, Anemia, Neutropenia, Myasthenia
Gravis, Guillain Barre Syndrome, Multiple Sclerosis,
Systemic Lupus, Rheumatoid Arthritis, Bullous Pamphigoid,
Kawasaki’s Syndrome, Chronic Fatigue Syndrome, and
Crohn’s disease, among others.

LACTOFERRINS: ANTIBACTERIAL, IRON BINDING, IRON

TRANSPORTER
Walker, Townsend Letter for Doctors, Aug. 1995, p 42-45;
'Infectious bugs are back but there’s a remedy’; The very
technology that saves people’s lives sets them up for infection,
says Robert Haley, MD Head of the epideimology and Preventative
Medicine unit at University of Texas in Dallas. Antibiotic resistant
organisms are an integral risk of any infection. After forty years of
aggressive antibiotic abuse physicians are now confronting
bacteria that have mutated defenses against drugs causing deaths
of patients who succumb to once treatable invasions. Even with the
thirty or so antibiotics the drug companies claim to be working on
there are no more potent antibiotics left to treat these drug
resistant bacteria. The only viable answer are natural remedies
comprised of antimicrobial cationic proteins that stimulate the
immune system, to be capable to defend against the supper
mutants and others. Lactoferrin is one of the strongest and most
active. (Lactoferrin is an abundant protein in colostrum) that works
at the mucosal surface. Lactoferrin is: 1) iron binding that deprives
bacteria of this essential growth mineral (nearly all bacteria cannot
grow without iron); 2) it is also directly antibacterial through
systemic immune responses, 3) has a high affinity N-terminus for
binding directly and inactivating bacteria by increasing bacterial
membrane permeability so that it can be neutralized by the body’s
natural immune functions. High affinity Lactoferrin receptors have
been identified on most immune cells: Lymphocytes, monocytes,
macrophages, and platelets. It is thought to regulate Cytokine
release. Lactoferrin is highly resistant to digestion and passes
intact to intestine where it does its work.

Spik, G. et. al., Immunology, Vol. 35 No 4, 663-671. (Bovine)

Colostrum contains a special iron binding protein called
Lactoferrin which was demonstrated at the Clinical Research
Center, Harrow, England to be highly antibacterial.

Spik, Genevive, et. al. 1983, Immunology, Vol. 35 No 4 pp. 663-

670: ‘Bacteriostasis of a milk-sensitive Strain of E. coli by
Immunoglobulins and Iron-binding Proteins in Association’; French
doctors showed that a combination of IgG and Lactoferrin in
colostrum was bacteriostatic for E. coli.
7 0
Moldoveanu, Zina, et. al., 1983, Annals of NY Academy of
Sciences, 409, pp. 848-850: ‘Antibacterial Properties of Milk: IgA,
Peroxidase and Lactoferrin Interactions’; Combination of
Peroxidase, Lactoferrin and IgA in (bovine) Colostrum
produces strong combined antibacterial effect. Peroxidase
enzymes oxidize bacteria by generating the release of
Hydrogen peroxide which bums up (hydrolyses) harmful
bacteria.

Hamilton, Whitney and Sizer, 1985, Nutrition: ‘Concepts and

Controversies’, West Pub. (nutritional textbook); (Bovine)
Colostrum contains a bifidus factor that favors the growth of
friendly intestinal bacteria. Also contains huge counts of
active Lactobacillus Bifidus. Also reported that Lactoferrin in
Colostrum keeps invading bacteria from getting iron needed
to reproduce.

Sanchez, et al, 1988, Biological Chemistry, Hoppe-Seyler, Vol.

369(9) pp. 1005-1008; ‘Concentration of Lactoferrin and
Transferrin (necessary to transport iron into blood) throughout
Lactation in Cow’s Colostrum and Milk’; Highest Concentrations
of both substances was found in the first milking, decreasing
sharply throughout the colostral period (48Hrs), then decreasing
more slowly.

Ushijima et. al., Dept, of Enteroviruses, Japanese National Health

Institute, Jan, 1991 V65(1) p54-60; 'Bacteriostatic activity of bovine
colostrum’; Immunoglobulin, Lactoferrin and Lactoferrin-Fe tested
using the automated antimicrobial susceptibility testing system.
Lactoferrin was found to be an even more effective antibacterial
than immunoglobulin. (Immunoglobulin is more effective against
viruses) The results indicated that all three had significant
bacteriostatic action.”

Brodie, Ainscough, et. al., Adv. Exp. Med. Biol.,1994 V 357 pp 33-
44; ‘Synergism and substitution in the lactoferrins: The anion
binding properties of human Lactoferrin Oxalate and hybrid
complexes exist in the human body’; Oxalate can displace
carbonate from either on or both anion sites depending on the
oxalate concentration, but no such displacement occurs for Fe2
although it does for bovine Lactoferrin.
LEAKY GUT SYNDROME AND THEIR RELATIONSHIP TO
DISEASE: HIV, AUTOIMMUNE AND OTHERS:

Galland, L. , 1995, Townsend Letter for Doctors, v 145(6) p 63-68;

Leaky Gut Syndrome: Breaking the viscious cycle’.

Crinsinger, K. D., et al, 1990, J Intern Med., Vol. 732: p145-54;

‘Pathophysiology of gastrointestinal mucosal permeability’

Deitch, E. A., 1990, Arch Surgery: Vol. 125: p403-4; The role of
intestinal barrier failure and bacterial translocation in the
development of systemic infection and multiple organ failure.’

Hazenburg, M. P. et al, 1992, Review Article Apmis, Vol. 100(1) p

1-9; ‘Are intestinal bacteria involved in the etiology of rheumatoid
arthritis?’

Rooney, P. L. et al, 1990, Clin Exp. Rheumatol, Vol8(1) p 75-83; ‘A

short review of the relationship between intestinal permeability and
inflammatory joint disease.’

Walker, W. A., 1975, Pediatr Clin. North Am., Vol. 22(4) p 731-46;
’Antigen absorption from the small intestine and gastrointestinal
disease’.

Bloembergen, P. et al, 1990, Arch Allergy Appl Immol., Vol. 92(2) p

124-30; ‘Endotoxin induced autoimmunity in mice’.

Pironi, L., et al, 1990, Dig Dis Sci, Vol. 35(50 p 582-8; ‘Relationship
between intestinal permeability and inflammatory activity in
asymptomatic patients with Crohn’s disease.’

Jenkins, R. T., et al, 1987, Br J Rheumatol, Vol. 26(2) p10-3-7;

‘Increased intestinal permeability in patients with rheumatoid
arthritis: a side effect of oral non-steroidal anti-inflammatory drug
therapy.’

Mielants, H., 1990, Clin Exp. Rheumatol, Vol. 8(5) p 523-4;

‘Reflections on the link between intestinal permeability and
inflammatory joint disease.’

Hamilton, I. et al, 1985, Q J Med., Vol. 55(221) p 559-67 ‘Small

intestinal permeability in dermatological disease’.
Jackson, P. G., et al, 1981, Lancet, Vol. 1(8233) p 1285-6;
‘Intestinal permeability in patients with eczema and food allergy.’

Batash, S., et al , 1992, Am J Gastro Vol. 87(5) p 680;‘ Intestinal

permeability in HIV infection: proper controls are necessary’.

Lim, S. G. Et al, 1993, Scand J Gastro, Vol. 28(7) p 573-80;

‘Intestinal Permeability and functioning patients infected with HIV’.
Bjarnason, I. Et al, 1984, Lancet, Vol. I p 79-82' The leaky gut of
alcoholism: the route of entry for toxic compounds’.

Ohri, S. K., et al, 1993, Ann Thorac Surg, v 55(5) p 1080-6;

‘Cardiopulmonary bypass impairs small intestine transport and
increases gut permeability’.

Grisham, M. B., et al, 1990, Inflammation, v 14(5) p 531-42;

‘Effects of neutrophil-derived oxidants on intestinal permeability,
electrolyte transport and epithelial cell viability’.

Doe, W. F., 1979, Am J Med., v 67(6) p 1077-84; ‘An overview of

intestinal immunity and malabsorbtion’.

Galland, L. Et al, 1993, J Adv. Med., v 6 p 67-82; ‘Intestinal

dysbiosis and the causes of disease’.

Katz, K. D. Et al, 1989, Baillieres Clin Rheum, v 3(2) p 271-84;

‘Intestinal mucosal permeability and rheumatological diseases’.

Wood, N. C., et al, 1987, Br J Psychiatry, v 150 p 853-6; ’Abnormal

intestinal permeability. An etiological factor in chronic psychiatric
disorders’.

Dohan, F. C. ,Et al, 1984, Biol Psychiatry, v 19(3) p 385-99;

‘Schizophrenia is rare if grain is rare; a study on gluten and gut
permeability’.

Klimberg, V. S., et al, 1990, Arch Surg, v 125(8) p 1040-5; ‘Oral

Glutamine accelerates healing of the small intestine and improves
outcome after abdominal radiation’.

Van der Hulst, R. R„ et al, 1993, Lancet, v 341(8857) p 1363-5;

‘Glutamine and the preservation of gut integrity’.
IMMUNE RELATIONSHIPS: ALLERGIC, DIABETIC
and AUTO-IMMUNE

Tortora, Funke, Cast, 1982, Microbiology, Published by

Benjamin/Cumming pp. 403-405. 'Specific defenses of the host:
Immunology’; B-cells of the immune system produce
immunoglobulins/antibodies. The IgE (immunoglobulin) thought
to be responsible for regulating allergic response. IgE found in
Bovine colostrum.

Crago, Mestecky, 1983, Survey of Immunology. Res., Vol. 2 No 2

pp. 164-169: ‘Immunoinhibitory Elements in Human Colostrum’; (A
protein substance was found in colostrum which inhibits the
overproduction of lymphocytes stimulated by antigens and
mitogens and may reduce symptoms associated with allergic
reactions.)

Staroscik, et. al., 1983, Molecular Immunology, Vol. 20 No 12 pp.

1277-82: Dr. Starosik and associates at the Institute of
Immunology at Wroclaw, Poland, discovered a small protein chain
Polyprotein-rich Peptide (PRP) of 9 amino acids in colostrum. This
chain has the same ability to regulate the activity of the immune
system as the hormones of the thymus gland. It activates an
underactive immune system, helping it move into action against
disease-causing organisms. PRP also suppresses an overactive
immune system such as is often seen in the autoimmune
diseases. PRP is highly anti-inflammatory and also appears to
act on T-cell precursors to produce helper T-cells and
suppresser T-cells. The effect is similar to that of thymus
hormones.

Julius, Janusz, Lisowski, Journal of Immunology, 1988 Vol. 140,p

1366-71 Dept, of Microbiology and immunology, Mcgill University,
Montreal, Quebec, Canada A Colostral protein (PRP) that induces
the growth and differentiation of resting B lymphocytes. “PRP
(Proline-rich Polypeptide) is the first protein of mammalian origin
that induces the growth and differentiation of reacting B
lymphocytes. PRP has been isolated from sheep and (cows)
colostrum. PRP is not species specific. Spleenocytes from
neonatal mice responded robustly to PRP with the growth and
differentiation of contained B cells to plaque formation. PRP did
not induce detectable Ig isotype switching”.
Newsweek, Nov. 15, 1993, p 73; A new way to fight Diabetes:
Researchers at UCLA and Stanford have diabetes cause by an
allergic reaction to a protein called GAD, immune systems in
diabetics turn against other antigens as well. A single injection
produced tolerance to GAD in mice eliminating the diseases
process."

Janusz, Lisowski, 1993, Arch. Immunol. Ther. Exp. Warz. Vol.

41(5-6): 275-9 Report on clinical study:
A. New immunomodulatory peptide found in bovine
colostrum: Proline-Rich Polypeptide (PRP)
B. Not Species specific (transferable to human use).
C. PRP increases permeability of skin vessels.
D. Causes differentiation of murine thymocytes into
functionally active T cells.
E. Simultaneously changes surface markers and function of
cells.
F. Results shown in treatment of auto-immune disorders and
sarcoma S-180 (cancer).
G. Important Immune modulator: stimulates underactive
immune system, tones down an overactive one.

Dohm, Elton, et al. Diabetes, Sept. 30, 1990 pp 1028-32: ‘lgF-1

Stimulated Glucose Transport’; lgF-1 stimulates glucose utilization.
lgf-1 found in bovine colostrum (identical to human) can
provide an effective acute treatment for Hyperglycemia, lgf-1
can be an effective alternative to insulin in stimulating transport in
diabetic muscle. Plasma levels of lgF-1 in diabetic patients is lower
than in nondiabetic groups. lgF-1 receptors present in human
muscles. IgF binding is 24% that of insulinlgF-1 stimulated glucose
transport twofold. Did not stimulate transport in obese subjects.”

Pennisi, Jan 15, 1995, Science News, Vol. 145, p37(1) Immune
therapy stems diabetes progress: “Researchers report that mice
treated with the anti-CD3 monoclonal antibody have been able to
resume normal regulation of their blood sugar. The results of
treatment are the first known to induce remission of the
development of diabetes and have kept the mice free of the
disease.”
CANCER: RESEARCH RELATED TO

Tokuyama, et. al., 1990, Dept, of Molecular Immunology, Cancer

Research Institute and Dept, of Nuclear Medicine, Kananawa
University, Kanaawa, Japan. Harwood Academic Publishers, UK:
Reported two new Proteins discovered in Bovine Colostrum:
BC-1 and BC-2. Belong to a new class of mitogenic inhibitors.
Reported that through biological activities resemble TgF-B.
Showed inhibitory effect on some sarcoma (cancer) tumor
cell lines in -sutro.

Paulik, et. al., 1985, Veterinari Medicina, Poland, Vol. 30 No 1 pp.

21-28: ‘Lysozyme in the Colostrum and Blood of Calves of Diary
Cows’; Lysoszyme in bovine (and human) colostrum is the
enzyme present in egg white, tears, saliva and other body
fluids that kills bacteria by dissolving their cell walls.

Toluyama and Tokuyama, 1989, Dept, of Molecular Immunology,

Cancer Research Institute and Dept, of Nuclear Medicine,
Kananawa University, Kanaawa, Japan. Harwood Academic
Publishers, UK. Cellular Biology Report 13, 251-258; “Bovine
Colostric Transforming Growth Factor-B-Like peptide induces
growth inhibition and changes morphology of human osteogenic
sarcoma (cancer) cells”: TgF B produced cell destruction in
certain human cancer (sarcoma) cells in cell culture growth
experiments in Japan.

Tokuyama and Tokuyama, 1993, Jour.Dairy Res. Vol. 60: 99-109

(Printed in Great Britain) Dept, of Nuclear Medicine, Fac. Med.
dept. Mol. Imm. Cancer Research Inst. Kanazawa Univ. Japan
Reported: A. Bovine Colostrum contains TgF-B. B. Excerpts
positive regulatory effects on accumulation of extracellular
matrix proteins. C. Suppressive effect on cytoxic monocytes.
D. Potent inhibiting effect on the generation of cytoxic
T Lymphocytes, NK and LAK cells. E. ANTI INFLAMMATORY.
F. Inhibits anchorage dependent cell growth of human
Osteosarcoma (cancer) cells (75% inhibition). G. Mediator of
fibrosis and angiogenisis ( Roberts et al., 1986), wound
healing (Sporn et al.., 1983) and bone formation (Centrella et
al., 1987).
Wada et. al., 1980, Infection and Immunity, 29, pp 545-550.
‘Neutralizing Activity Against Clostridium Difficile Toxins in the
Supernatants of Cultured Colostral Cells’; Colostrum immune
factors neutralize crude toxins

Hakansson, et. al., Proceedings, the Nation Academy of the

Sciences, Vol. 92, pp. 8064-8068 Aug. 1995, Research Study:
Lund University, Stockholm, Sweden. Study showed in vitro effect
of ingredient in human milk and colostrum: Multimeric a-
Lactalbumin caused lung cancer (transformed epithelial cells) to
create selective suicide, (apatosis). Normal surrounding cells
unaffected. Conclusion: Multimeric a- Lactalbumin is a potent
Ca2+ -elevating and apoptosis-inducing agent with broad, yet
selective, cytoxic activity.

Moro, et. al., 1985, Cellular Immunology, 93(2) pp. 467-74: 'Natural
Killer Cells in Human Colostrum’; Approximately 0.5% of colostral
cells were identified as natural killer cells of two morphological
types.

Business Week, Feb. 6, 1995: 'Quiet Strides in the War on

Cancer’; “National Cancer Institute researcher Steven A.
Rosenberg became a media sensation when he achieved success
with cancer patients in 1985 using an experimental technique
called immunotherapy. Since cancers can invade the immune
system, why not load the body with killer immune cells, along with
special chemical messengers called Cytokines that give the body
an extra kick.” Treatments partially successful. More trials ongoing.
Cytokine for cancer vaccines is the largest single protocol under
study today.

HEART DISEASE:

Lange, Schreiner, Apr.21, 1994, New England Journal Of

Medicine, Vol330 p1129(7) ‘Immune Mechanisms of cardiac
disease’; “Many cardiac diseases are the result of immune
sensitization to cardiac antigens. Such immune mediated injury
results in the presence of inflammatory cells within the
myocardium, leading to myocarditis. Cellular, rather than humoral
(antibody based), immunity has been the target of most of the
research conducted on immune-related heart disease, with
lymphocytes and macrophages being the predominant infiltrating
cells. Cardiac disease associated with immune mechanisms
include giant-cell-associated cardiomyopathy and primary
77
idiopathic myocarditis. Research aimed at discovering the
mechanisms by which myocardium, affect muscle cell functions
and rearrange myocardial cell architecture has greatly increased
the medical community’s knowledge of the immune mechanisms of
heart disease. The development of successful drug therapy for
such conditions is now considered possible.”

HERPES: RELATED RESEARCH

Rouse, B. T. et. al., 1976, Infection and Immunity, 13, pp. 1433.
'Antibody-dependent Cell-Mediated Cytoxtoxicity in Cows:
Comparison of Effector Cell Activity Against Heterologous
Erythrocyte and Herpes-Virus-Infected Bovine Target Cells’;
“ Bovine leukocytes have antibody dependent cell-mediated
cytoxciity against bovine herpes virus.” Bovine Colostral cells
with antibody were able to kill cells infected with herpes
simplex in vivo.

Kohl, S. et. al., 1978, Journal of Clinical Laboratory Immunology, 1,

pp. 221-224. ‘Human Colostral Cytotoxicity: Antibody-Dependent
Cellular Cytotoxicity Against Herpes Simplex-Infected Cells
Mediated by Colostral Cells'; Colostral cells along with antibody
were found to destroy herpes simplex-infected cells.

Raloff, Science News, Apr. 15, 1995 Vol. 147 p231(1) More Ways
Mother’s milk fights disease: Contains Retinoic Acid which helps
baby fight herpes virus. The Glycoprotein kappa casein protects
against bacteria that causes stomach ulcers, (Retinoic acid and
kappa casein found in colostrum also).

Isaacs, et. al., 1995, Science, April p.p. 231: Reporting in

Experimental Biology 95: teams confirmed colostrum delivers
not just antibodies but a battery of infection fighting agents.
Among them, retinoic acids a Vitamin A derivative. Dr. Charles
E. Isaacs et. al. at New York State Institute for Basic Research
on Staten Island, NY, infected culture cells with herpes virus,
his findings were that only retinoic acids conferred protection
and reduced colonization. He concluded that while retinoic
acids were not a cure, it effectively reduced the herpes virus
to levels ( 1/100 to 1/10,000 viruses remained active after
treatment) where the bodies immune system could fight off an
outbreak.
AIDS: TREATMENT OF (AND RELATED HOST
INFECTIONS)

Immunoglobulin to Prevent Nosocomial Infections, New

England Journal of Medicine, July 23, 1992, Vol. 327 No 4 p 269.
Immunoglobulin from bovine colostrum effective in reducing
and preventing (viral and bacterial) infections in immune
deficient subject: bone marrow recipients, premature babies,
AIDS, etc. Problem: obtaining high and consistent levels of
functional antibodies though donor selection. Could improve
through pooled selection, selective donor immunization.

Ebina, et. al„ 1983, The Lancet, Vol. 29 No 2 pp. 1029-1030:

‘Prevention of Rotavirus Infection By Cow Colostrum Containing
Antibody Against Human Rotavirus’; Japanese researchers
exposed cattle to oral doses of rotavirus which causes severe
diarrhea and bowel inflammation in humans. Colostrum from
these cows contained antibodies which, when fed to humans,
prevented them from getting rotavirus.

Stephan, Dichtelmuller and Lissner, 1989, Journal of Clinical

Chem. and Clinical Biochem., Vol. 28, 1990, no 1: ‘Antibodies from
Colostrum in Oral Immunotherapy'; Spray dried concentration of
immunoglobin preparation for oral use from pooled source of
100 cows was found to be highly effective in treatment of
severe diarrhea e.g. in AIDS patients. After treatment no
Cryptosporidia were found in stools where it had been
previously detected.

Foothill, Oak and Mott, 1990, Archives of Disease in Childhood,

Vol. 65 p.p. 813-14. Case Report: Favorable treatment of
Cryptosporidiosis with pooled bovine colostrum via oral
administration was reported

Nord, DiJohn, Tripori, Tacket, 1990, AIDS, Vol. 4(6) pp. 581-4:
'Treatment with bovine hyperimmune colostrum of cryptosporidial
diarrhea in AIDS patients’; Double Blind, controlled pilot study
of hyperimmune colostrum in five aids patients by nastric
infusion. Conclusion that treatment was effective.
Ungar, Ward, Fayer and Quinn, 1990, Gastroenterology, Vol. 98
pp. 486-89: ‘Cessation of Cyptosporidium-Associated Diarrhea
in an AIDS Patient after oral treatment with Hyperimmune
Bovine Colostrum’; Cryptosporidium absent after treatment.

Flanigan, Marshall, Redman, Kaetzel, Ungar, 1991) Journal.

Protozool Nov-Dec, Vol. 38(6): 225s-227s A. Diarrhea producing
Cryptosporidium parvum infection treated effectively with oral
ingestion of bovine colostrum. B. Also effective in treatment
of prophylaxis and rotavirus gastroenteritis

Desert News, Salt Lake City, Utah June 19, 1991 Mentioned Study
by protozoologist Ron Fayer US Dept, of Agric.: two AIDS
patients with Cryptosporidium caused diarrhea were relived of
symptoms in treatment with hyperimmune colostrum. A larger
study to continue at Johns Hopkins Hospital. Dr. Bruce
Anderson a veterinary pathologist at the University of Idaho
stated: “There have been over SO drugs tried to relive AIDS
patients diarrhea, they didn’t work. But this hyper immune
colostrum does.” Anderson is credited with suggesting this
form of therapy because he noticed that a number of
veterinary students would come down with cryptosporidiosis
after contact with cattle who had disease. He theorized that
immune capability could be transferred to humans.

Flanigan, Marshall, Redman, Kaetzel, Ungar, 1991) Journal.

Protozool Nov-Dec, Vol. 38(6): 225s-227s
A. Diarrhea producing Cryptosporidium parvum infection
treated effectively with oral ingestion of bovine colostrum. B.
Also effective in treatment of prophylaxis and rotavirus
gastroenteritis C. Hyper immune cows colostrum and regular
cows colostrum compared: Parasite reduction of 82% with
administration of hyperimmune colostrum and 67% with
administration of regular pooled bovine colostrum.

Jage, Kampmann, Kolb, et. al., 1992, Clin. Investigation Jul.;

70(7): 588-94 Reported: A. Immunoglobulins from bovine
colostrum (lactobin biotest) contain high titers of antibodies against
a wide range of bacterial, viral and protozoa pathogens, as well as
against various bacterial toxins. B. Lactobin quite resistant to
gastric acids. C. Effective in the treatment of opportunistic
infections that cause diarrhea. Treatment and effectiveness in
AIDS patients verified, where no other treatment was effective.
Rump, et. al., 1992, Clinical Investigator, Vol. 70 pp. 588-94:
Treatment of Diarrhea in AIDS and bone marrow transplant
patients with Bovine Colostrum: Reported colostrum quite
resistant to gastric juice. Oral treatments very effective. No
side effects.

New Scientist, Jan 8, 1994: Reported an Australian Co. has

been involved in successful human trials with an oral
administration of over 500 patients in hospitals in India, Hong
Kong and Australia with hyperimmune colostrum specific for
rotavirus a diarrhea causing virus rampant in third world
countries but common in developed countries also.

Fisher, Jeffery, 1994, Futurist Nov-Dec: “Book Review; 'The

Plague Makers’; Simon And Schuster, NY; “Antibiotics taken in
successive and prolonged doses may suppress the immune
system enough to allow unusual forms of mycroplasma bacteria to
develop. These bacteria interact with HIV to form AIDS. Antibiotics
act as catalyst for the process.” Warns against the reliance on
antibiotics. Suggests alternative means to stimulate immune
response.

Deseret News, SLC, Utah, Apr. 6, 1995: Component of Human

Milk Blocks HIV infection: Research reported in the March issue
of the Journal Of Nutrition by David Newburg of the Harvard
Medical School, reported a component called chondroitin sulfate
blocks the binding of HIV to its host cell receptor. This could limit
the postnatal transmission of HIV in breast fed infants of HIV
infected mothers.

Nowa, McMichael, Scientific American Aug. 1995 p58-65. ‘How HIV

defeats the immune System'; Continuous and dangerous evolution
of HIV virus underlies body and medical sciences inability to find
means to defeat. Vaccines not effective, virus mutates too quickly
and there are too many mutant variations. Reducing viral levels
in the body and stimulating natural immune capabilities have
the most promise to help natural immune system contain the
virus.

Harmsen, et al., Jour. Infectious Disease 1995 V. 172 p 380-8

Antiviral effects of plasma and milk proteins; Lactoferrin shows
potent activity against both Human Immunodeficiency Virus
(HIV) and Human Cytomegalovirus (HCMV) in vitro:
8 1
“Only native and conformationally intact Lactoferrin from
bovine colostrum or human milk could completely block
Cytomegalovirus infection. Moreover, native Lactoferrin also
inhibited the HIV-1 induced cytopathic effect. When negatively
charged groups were added to Lactoferrin by succinylation
there was a 4-fold increased anti-viral effect on HIV.
Lactoferrin likely exerts its effect at the level of virus
absorption or penetration (or both), because after
cytomegavirus penetrated cellular tissue the ongoing infection
could not be further inhibited”.

GROWTH FACTORS: IMPLICATIONS IN

HEALING AND PHYSIOLOGY
Klagsbrun, 1978, Proceedings of the National Academy of
Sciences, 75, pp.; 5057-5061. 'Human Milk Stimulates DNA
Synthesis and Cellular Proliferation in Cultured Fibroblasts’;
Growth Factors in milk showed 100 times the potency of serum
when tested on fibroblasts.

Gil, Angel, Sanchez-Medina, 1981, Journal of Dairy Research, Vol.

48 Vol. pp 35-44. 'Acid Soluble Nucleotides of Cow’s, etc.’; Bovine
Colostrum was found to contain seven different nucleotides
which are important for normal cell function and repair.

Ballard, Neild, Francis et. al., 1982, Journal of Cellular Physiology,

110 pp 249-254. The Relationship Between the Insulin Content
and Inhibitory Effects of Bovine Colostrum on Protean Breakdown’;
Insulin-like ingredient in bovine colostrum (lgF-1) slows
protein breakdown. Protein breakdown was also slowed by
addition of colostrum to a cell line known to be unresponsive
to insulin, indicating the presence of non-insulin growth
factors in bovine colostrum.

Sporn, et. al., 1983, Science, 219 pp. 1329-31: 'Polypeptide

Transforming Growth Factors (TGF A & B) and Epithelial Growth
Factor Isolated from Bovine Colostrum Used for Wound Healing in
Vivo’; Growth factors in bovine colostrum were found to be
very effective in promoting wound healing. Implications for
trauma, and surgical healing. External and internal
applications implied.
Ballard et. al„ Biochem J. 1983 V 210, 243-249: Effects of
anabolic agents on protein breakdown’; “Protein degradation is
inhibited by bovine colostrum. Anabolic agents such as
trenbolone, diethylstilbestrol, and testosterone do not alter rates of
intercellular protein breakdown."

Shimizu, Webster, Morgan, Blau and Roth, 1986, American

Physiological Society, Dept, of Pharmacology, Stanford University,
School of Medicine: A. Presence of IGF-1 Receptors in human
muscle cells confirmed.

Noda, et. al., 1984, Gann, Vol. 75, 109-112. Japanese

researchers discovered that Transforming Growth Factors A
and B (TGF A & B) in bovine colostrum were involved in
normal cellular activities such as embryonic development, cell
proliferation, and tissue repair. They also reported it promoted
the synthesis and repair of DNA • the master code of the cell.

Francis, 1986, Biochemical Journal, 233(1) pp. 207-213;

‘Purification and Partial Sequence Analysis of Insulin-like Growth
Factor 1 from Bovine Colostrum’; Showed Bovine lgF-1 to be
identical to human lgF-1. Described purification process for
extraction of lgF-1 from colostrum.

Roberts, Sporn, Assoian, et. al., 1986, Procedures of the National

Academy o f Sciences, Vol..83, pp. 4167-71: Transforming Growth
Factor Type B: Rapid Induction of Fibrosis and Angiogenesis in
Vivo and Stimulation of Collagen Formation in Vitro’; Ristow, et
al., pp. 5531-5533 Reports BSC-1 growth inhibitor type B
transforming factor is a strong inhibitor of thymocyte (T-lymphocyte
precursor) proliferation ( presence in bovine colostrum confirmed:
Noda, 1984)

Seyedin, Thompson, Bentz, et. al., 1986, Journal of Biol.

Chemistry, Vol. 261, pp. 5693-95: Reported Cartilage Inducing
Factor-A in colostrum and its apparent affinity to
Transforming Growth Factor B (in human and bovine
colostrum), and its relationship to cartilage repair.

Ballard, Francis, Geoffry, 1983, Journal of Biochemistry, Vol. 210

pp. 243-249: ‘Effects of Anabolic Agents on Protein Breakdown in
L6 Myoblasts'; Describes how protein breakdown in tissue due
to injury is inhibited by several anabolic agents especially an
insulin-like substance (lgF-1) found in bovine colostrum.
8 3
Francis, Upton, Ballard, McNeil, 1988, Journal of Biochemistry,
Vol. 251: 95-103 (printed in Great Britain): ‘Insulin-Like Growth
Factors 1 & 2 in Bovine Colostrum’; Two growth factors similar to
insulin were purified from bovine colostrum lgF-1 found to be
identical to the corresponding human growth factor. In this
experiment protein synthesis was increased and protein
breakdown was reduced by administration of the bovine
colostrum extracts.

Oda, Shinnichi, et. al., 1989, Comparative Biochemical Physiology,

A: Comparative Physiology, Vol. 94A No 4 pp. 805-808: ‘Insulin-
Like Growth Factor 1, GH, Insulin and Glycogen Concentration in
Bovine Colostrum and in Plasma of Dairy cows’; Bovine
colostrum contains high levels of growth factors that promote
normal cell growth and DNA synthesis.

Tollefsen, Lajara, McCusker, Clemmons, 1989, Journal of

Biological Chemistry, Vol. 264 No 23, Aug. 15: ‘Insulin-Like Growth
Factors (IgF) in muscle Development’; IgF’s role in differentiation,
repair, synthesis, and their interplay with other necessary growth
factors. lgF-1 only factor that can stimulate muscle growth and
repair by itself. Eliminates catabolism and stimulates
anabolism at the cellular level.

Allen and Rankin, 1990, PSEBM Vol. 194, Muscle Biology Group,
Dept, of Animal Sciences and Physiology, Univ. of Arizona,
Tucson, AZ. Reported: A. Fibroblast growth factor (FGF)
stimulates proliferation but depresses differentiation of
muscle cell growth. B. Insulin Like Growth Factor (IGF-1)
stimulates both. C. Transforming Growth Factor (TGF-b)
slightly depresses proliferation and inhibits differentiation.
Conclusion: When administered in combination these factors
induce satellite cells to grow, regenerate and proliferate.
Following, these cells will fuse with one another or the
adjacent muscle fiber thereby increasing myonucles numbers
for growth and repair. All three Factors found in Bovine
Colostrum

Marcotty et. al., Growth Regulation 1991 Longman Group UK: ‘IgF-
1 from cow colostrum: Characterization’; lgF-1 potent stimulator of
growth and differentiation of numerous cell types. Bovine
sequence identical to Human lgF-1
Ullman, et al. Acta Physiol Scand. 1990 v 140 p 521-5. ‘Effects of
Growth Hormone on muscle regeneration and lgf-1 concentration
in old rats’; “High age is associated with reduced levels of GH
and lgF-1. Administration of growth hormone raises level of
lgF-1 to that of young rats. With increased lgF-1 the reduced
protein synthesis of old rats is restored, caused increased
muscle tissue in normal and regenerating muscle tissue, and
increased maximum contraction force.”

Patureau- Mirand, Posone, Levieux, Attaix, et. al, 1990, Biol.

Neonate Vol. 57(1): 30-6; Reported that Colostrum stimulated
intestinal protein synthesis.

Skottner, Arrhenius-Nyberg, Kanje and Fryklund, 1990, Acta

Paediatric Scand. (suppl) 367: 63-66, A. lgF-1 resulted in
significant body weight gain and significant bone growth.
B. Topical administration to wounds resulted in more effective
healing. C. Stimulated nerve regeneration

Dohm, Elton, Raju, Mooney, Pories, Flicklinger, Atkinson, 1990,

Diabetes 39: 1028-32, Reported that: A. lgF-1 Stimulates
glucose utilization. B. lgF-1 receptors in muscle tissue is
normally occurring in humans. C. lgF-1 effective treatment for
Hyperglycemia

Tomas, Knowles, Owens, Read, Chani, Gargosky and Ballard,

1991, Biochem Journal Vol. 276. pp. 547-554. Reported: A. Igf-
1 peptides stimulate muscle protein synthesis and improve
nitrogen balance. B. Des (1-3) IGF-1 is at least as potent as the
full length lgF-1. C. Bovine Colostrum is natural source of both
factors

Thissen, et. al. Endocrinology, 1991 V 129 p 429-35: Evidence that

pretranslational and translational defects decrease serum IGF-1
concentrations during dietary protein restriction: “ Dietary protein
restriction causes GH (growth hormone) resistance and
decreases lgF-1 serum levels.” (Implications in loss of muscle
mass related to protein depravation).

Shawn, D. 1992, Ironman, Aug. Article on positive effects of growth

factors in bovine colostrum with weight lifting and athletic
endurance.
Lundeberg, et. al. W. B. Saunders Co. 1991: 'Growth Hormone
improves Muscle Protein Metabolism'; Human Study indicated. GH
prevented catabolism in muscle and improved whole body
nitrogen economy. Investigations of the possible beneficial
effects of GH to prevent skeletal muscle deterioration after
surgical trauma are advocated.”

Resnicoff, Sell, et al. Jour. Biol. Chem. 1993, v 268 p 21777-82:

‘Ethanol inhibits autophosphorylation of IGF-1 receptor and IGF-1
mediated proliferation'; “Findings demonstrate that ethanol at
low concentrations markedly inhibits IGF-1 receptor
autophosphorylation and IGF-1 mediated cell growth.”

Breese, et. al., Jour. Gerontology (aging) 1991 V 46 p B180-7:

'Influence of age and long term dietary restriction on IGF-1’;
“Study of relationship of IGF-1 and life-span: Demonstrated a
decrease in relative IGF-1 concentration with age , as well as
dietary restriction. Indicates aging associated with reduced
levels in plasma IGF-1 and other GH levels.” Implications as
anti-aging.

Resnicoff, et al., Lab Invest 1994, v 71 p 6557-62. Dept, of

Pathology Jefferson Medical College Philadelphia, Penn: 'Ethanol
inhibits IGF-1 mediated signaling and proliferation’; “Ethanol
at physiologically tolerated levels markedly inhibited growth
of cells in response to presence of IGF-1.”
(Conclusion: that relatively low levels of ethanol inhibits cell
mediation and differentiation i.e.: growth

Chaumeil, Liolet, Kogbe, 1994, Adv. Exp. Med. Biol. Report of

clinical study Vol. 350 pp. 595-599; Reported effective treatment
of eye infections with bovine colostrum lactoserum i.e.:
reduction in glaucoma, scaring after injury or surgery,
reduction in eye lesions.

Xu, Mardell et. al., Immunology 1995 vol 85 p 394-9: Expression of

functional lgF-1 receptor on lymphoid cells: “Our studies suggest
that biological activities of lgF-1 include direct stimulation of
immune cells and that expression of lgF-1 receptor may
have a role in the regulation of T-cell function.”
Bhora, et. al. Jour. Surg. Res. 1995 V 59 p 236-44: 'Effect of
growth factors on cell proliferation in human skin’; “The failure of
chronic wounds to heal is a major medical problem. Studies
suggest an important role for growth factors in promoting
wound healing. Conclusion: Fibroblast growth factor IGF-1
and epithelial growth factor are important for wound healing.”
Treatment implications for trauma and surgical wounds,
accelerated healing possible.

Bak, Moller, Schmitz, Medical Endocrinological Dept. Ill, University

Clinic of Internal Medicine, Aahus Kommunehospital, Aarhus,
Denmark: GH inhibited the insulin stimulated glucose disposal by
27% and raised non-protein energy expenditures Fat Oxidation
contributed 71.7% of Energy expenditures during GH
administration as compared with 48% without. Conclusion GH
increases energy expenditures and inhibits glucose oxidation
in favor of increased lipid (fat) oxidation (burning).”

Gluckman, Breir and O’Sullivan, Dept, of Pediatrics, Univ. of

Auckland, New Zealand: A. IGF-1 inhibits malnutrition induced
catabolism. (If actively present IGF-1 stops the burning of
body proteins, {muscle} for energy)

Ullman, Sommerland, Skottner, Dept, of Pathology and

Pharmacology, Univ. of Gothenburg, Sahlgren Hospital &
HabiVitrum AB, Stockholm, Sweden: A. High age associated with
reduced levels of GH and lgF-1. B. Induction of GH and lgF-1
increase body weight through muscle growth of aged subjects

‘ Rosenthal, Brown, Brunetti and Goldfine, Dept, of Pediatrics,

Univ. of California, SF Div. of Diabetes and Endocrine Research,
Mount Zion Medical Center, Univ. of Ca., SF
A. Presence of FGF (Fibroblast Growth Factor) (in bovine
colostrum) inhibits IgF-ll’s ability to decrease lgF-1 receptors
in muscle tissue resulting in a 60-70% increase in lgF-1
binding.

1 Preston, Robert, N.D. International Institute of Nutritional

Research, 1987
2 Haley, Robert, M.D. Director Epidemiology and Preventative
Medicine Unit at the University of Texas Health Science Center,
Dallas, Texas
3 Shawn, Daniel, B.S. Ironman Magazine, Aug 1992
4 Preston, Robert, see 1
8 7
 The medical and health information in this book are based
on the training and research of the authors. Because each person
and situation is unique, the publisher/authors urge the reader to
check with their own health professional before making any use
decisions. The publisher/authors are not responsible for any
adverse effects or consequences from the use of the suggestions
or procedures presented in this book.

There is one thing that needs to be stressed at this point.

Colostrum is not a cure for cancer or any other debilitating
disease. This book is not about cure but mitigation, delay, natural
defense and care. Colostrum provides a means to assist, and quite
significantly, make a difference in the promotion of good health!
ABOUT THE AUTHORS
DANIEL G. CLARK, M.D.

Doctor Clark resides in Indialantic, Florida, with his wife

Carolyn and their five children. He received his Doctorate of
Medicine from the Medical College of Georgia and completed his
residency (OB-GYN) at University Hospital, Jacksonville, Florida.
He has had a very impressive career. In 1988, Doctor Clark
received the ‘Physician of the Year Award’, in Broward County,
Florida, and in April, 1984, he was awarded the prestigious
‘Academic Award for Scientific Research in Cancer’ (Academia
Internationale Di Pontzen) in Rome, Italy. Presently, he is the
Managing Director of his company, Bio Active Nutritional, Inc., and
is actively involved with numerous professional associations and
teaching centers. Doctor Clark sponsors educational seminars for
physicians worldwide, providing lectures on quantum and molecular
medicine. His special interests are chelation therapy for
Arteriosclerosis, alternative treatments for cancer and homeopathy
and herbology for the prevention and treatment of chronic disease.

KAYE WYATT

Kaye Wyatt is a retired teacher who has currently dedicated

herself to informing people everywhere of the benefits of colostrum.
This commitment arose out of her own healing experience with this
amazing superfood. Kaye’s new career as a writer is a direct
outgrowth of her commitment to spread the word about colostrum,
and has led to appearances on national radio, television, and at
health-oriented expositions. She lives in Sedona, Arizona with her
husband, Doug.
 X 0 yjiTX G O lO G liü J M
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Colostrum, life’s first food, is produced by the mother’s mammary

glands during the first 24-48 hours after birth. This special non-milk
fluid contains powerful immune and growth factors to insure the
survival and healthy growth of the newborn. Our body’s growth and
immune factors decline after puberty or with illness. Colostrum has
been shown to be the only supplement that can replace these vital
components of life and only bovine colostrum, from dairy cows, has
been shown to be safe and biologically transferable for human use.

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