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BAcC, FRCHM, Uk 1
Behandlungsstrategien bei Krebserkrankungen, Rothenburg 2010
A. Aus Sicht der CM kann die Chemotherapie als ein Eindringen von
Toxinen bewertet werden, die zu Beginn die Entwicklung von Hitze im Blut
auslöst und Jing schmälert.
Folgende Strategie einschließl. der 3. Gabe der Chemo z. B. bei
FEC (Fluorouacil, Epirubicin, Cylophosphamid) bei Mamma-Ca2
1
Prozentzahlen reflektieren meinen persönlichen Behandlungsansatz
2
Ge Zhi Yu Lan, by Zhu Dan Xi: If a woman is out of favour with her husband or
brother/sister in law, worry, anger, depression and oppression will accumulate day and night.
Barbara Kirschbaum, B.AC. BAcC, FRCHM, Uk 2
Behandlungsstrategien bei Krebserkrankungen, Rothenburg 2010
o Toxine eliminieren
Bai Hua She She Cao, Shan Dou Gen, Pu Gong Ying, Shan Ci Gu usw
o Blut beleben, kühlen
Hu Zhang, Chi Shao, Mu Dan Pi
o Jing nähren, Blut kräftigen
Huang Jing, Shan Yao, Ji Xue Teng, Gou Ji Zi,
Kräftigung des Zheng-Qi:
Huang Qi, Dang Shen, Shan Yao, Bu Gu Zhi
o Kräuter, die eine antikarzinogene Wirkung haben und die Wirkung der
Chemo optimieren
San Qi (bei Darm-Ca), Zhu Ling, Yi Yi Ren (bei Tumoren des
Verdauungstraktes und Lu-Ca)
o Kräuter, die eine positive Wirkung auf die Bildung der Erythrozyten
und der Leukozyten haben (siehe Dang Gui Ji Xue Tang), Ku Shen
(Huang Qi 30 gr. Ji Xue Teng 30 grFu Linf, 10, Gou Qi Zi 10 gr, Tai Zi
Shen 10, Tu Si Zi 10 gr, Nu Zhen zi 10 gr)
B. Die Wirkung der Chemotherapie steigert sich von mal zu mal, ab ca. der
dritten Gabe zeigen sich neben den toxischen Wirkung nun auch eine
Schwächung des Yin und des Qi ein. In der Regel kommt es zu einer
gefährlichen Abnahme der weißen und roten Blutkörperchen, vermehrt treten
nun Muskelschmerzen, Fatigue und Entzündungen der Schleimhäute auf.
The spleen qi will be dispersed and impeded and the liver qi will counterflow wildly.
As result, a dormant node will develop gradually as big as a chess piece with no pain and
itching. It takes tens of years to develop into a sunken sore, called breast rock, it forms a
depression like a rock cave. This is incurable,. If at the initial stage of its generation one
eliminates the root of the disease by keeping the heart tranquil and the spirit calm and then
carries out a proper treatment method, there is the possibility of healing.
Qing Pi Tang
Barbara Kirschbaum, B.AC. BAcC, FRCHM, Uk 3
Behandlungsstrategien bei Krebserkrankungen, Rothenburg 2010
Aus Sicht der CM führt stellt die Bestrahlung eine extreme Form von Hitze
dar, die sich zu toxischer Hitze umwandeln kann. Sie schädigt nicht nur lokal
sondern auch systemisch die Körperflüssigkeiten, konsumiert Yin, verursacht
lokale Blutstagnation und reduziert die Kraft des Aufrechten Qi.
Wichtig bei Bestrahlung sind Kräuter, die das Entstehen von toxischer Hitze
an der Hautoberfläche reduzieren z.B. Jin Yin Hua, Pu Gong Ying, Lian
Qiao, Ye Ju Hua, Hong Hua. Gleichzeitig muss das Yin unterstützt werden
mit Sha Shen, Bai He oder Mai Men Dong.
Frauen mit ER+ Mammakarzinom werden über ca. 3-5 Jahre mit Tamoxifen
weiterbehandelt. Die meiste Frauen treten dadurch in die Menopause ein und
haben entsprechende Symptome, die mit CM gut behandelbar sind.
Barbara Kirschbaum, B.AC. BAcC, FRCHM, Uk 4
Behandlungsstrategien bei Krebserkrankungen, Rothenburg 2010
Auswirkungen der Chemotherapie aus Sicht der chinesichen Medizin
Jing Xu
tox. Hitze
Chemotherapie
schädigt direkt Qi,Blut und Yin von
-Toxin
(Hand-Fuß-Syndrom)
Anämie, Leukopenie
* Schädigt Qi schädigt Blood Wind
Herz Thrombozytopenie
Lungen
Nieren Neuropathie
Leber
gegenläufiges Ma Qi Milz und Magen Qi xu Feuchtigkeit,
Schleim
Übelkeit und Erbrechen,
Verstopfung
Anorexie, Fatigue Durchfall,
Kardiotoxicity, Beinschwere
erhöhte Lebertransaminasen
Niereninsuffizienz
Barbara Kirschbaum, B.AC. BAcC, FRCHM, Uk 5
Behandlungsstrategien bei Krebserkrankungen, Rothenburg 2010
Antikarzinogene Kräuter
K.Chan1 Pan Mingji 2 Researchauswahl Pub Med
Bai Hua She She Cao Bai Hua She She Cao
Bai Jiang Cao
Bai Zhu Ban Zhi Lian
Ban Xia,
Bu Gu Zhi Chuan Lian Zi Dang Shen
Da Huang Chi Shao Dang Gui
Dan Shen Dan Shen Gui Sui Bu
Fu Ling Dang Gui E Zhu
Gan Cao Fu Zi
Gua Luo Hong Hua Huang Qi
Huang Lian Huang Jing Huang Lian
Jin Yin Hua Jiang Can Ji Xue Teng
Ku Shen Mo Yao Ling Zhi
Long Kui Mu Dan Pi
Nu Zhen Zi Quan Xie
Ren Shen Ru Xiang
Shi Chang Pu, San Qi San Qi
Sheng Ma San Leng Shan Zhu Yu
Tian Hua Fen
Wu Mei
Xia Ku Cao
Xian He Cao Yi Mu Cao
Xing Ren Wu Gong Yi Yi Ren
Yi Yi Ren Yan Hu Suo Yan Hu Suo
Yu Xing Cao Yu Jin Zao Xiu
Zhu Ling Zhu Ling
1
Kelvin Chan: Interactions between Chinese herbal products and orthodox drugs, harwood academic
publishers
2
Pan Mingji, Cancer treatment with Fu Zheng Pei Ben Principle, Fujian Science and Technology Pub.House,
Beijing1987
McCulloch M, See C, Shu XJ, Broffman M, Kramer A, Fan WY, Gao J, Lieb W,.
J Clin Oncol. 2006 Jul 1;24(19):3215-6; author reply 3216-7. University of California,
Berkeley School of Public Health, Division of Epidemiology, Berkeley, CA 94720, USA.
PURPOSE: Systemic treatments for advanced non-small-cell lung cancer have low efficacy and
high toxicity. Some Chinese herbal medicines have been reported to increase chemotherapy
efficacy and reduce toxicity. In particular, Astragalus has been shown to have immunologic
benefits by stimulating macrophage and natural killer cell activity and inhibiting T-helper cell
type 2 cytokines. Many published studies have assessed the use of Astragalus and other Chinese
herbal medicines in combination with chemotherapy. We sought to evaluate evidence from
randomized trials that Astragalus-based Chinese herbal medicine combined with platinum-based
chemotherapy (versus platinum-based chemotherapy alone) improves survival, increases tumor
response, improves performance status, or reduces chemotherapy toxicity. METHODS: We
searched CBM, MEDLINE, TCMLARS, EMBASE, Cochrane Library, and CCRCT databases for
studies in any language. We grouped studies using the same herbal combinations for random-
effects meta-analysis. RESULTS: Of 1,305 potentially relevant publications, 34 randomized
studies representing 2,815 patients met inclusion criteria. Twelve studies (n = 940 patients)
reported reduced risk of death at 12 months (risk ratio [RR] = 0.67; 95% CI, 0.52 to 0.87).
Thirty studies (n = 2,472) reported improved tumor response data (RR = 1.34; 95% CI, 1.24 to
1.46). In subgroup analyses, Jin Fu Kang in two studies (n = 221 patients) reduced risk of death
at 24 months (RR = 0.58; 95% CI, 0.49 to 0.68) and in three studies (n = 411) increased
tumor response (RR = 1.76; 95% CI, 1.23 to 2.53). Ai Di injection (four studies; n = 257)
stabilized or improved Karnofsky performance status (RR = 1.28; 95% CI, 1.12 to 1.46).
CONCLUSION: Astragalus-based Chinese herbal medicine may increase effectiveness of
platinum-based chemotherapy when combined with chemotherapy. These results
require confirmation with rigorously controlled trials.
Effect of citronellol and the Chinese medical herb complex on cellular immunity of cancer
patients receiving chemotherapy/radiotherapy.
Zhuang SR, Chen SL, Tsai JH, Huang CC, Wu TC, Liu WS, Tseng HC, Lee HS, Huang MC,
Shane GT, Yang CH, Shen YC, Yan YY, Wang CK.
Graduate Institute of Nutritional Science, College of Health Care and Management, Chung Shan Medical
University, Taichung, Taiwan.
Leukopenia and immunity impairment usually occur during cancer therapy. Citronellol, an oil
soluble compound derived from the geranium, has anticancer and antiinflammatory properties,
as well as promoting wound healing. Ganoderma lucidum, Codonopsis pilosula and Angelicae
sinensis are traditional Chinese herbs, all of which have proven immunomodulatory functions in
laboratory-based research. This randomized, double-blind, placebo-controlled study examined
whether the Chinese medicinal herb complex (CCMH; a mixture of citronellol and extracts of G.
lucidum, C. pilosula and A. sinensis) improves the immune cell counts of cancer patients
receiving chemotherapy and/or radiotherapy. A total of 105 cancer patients receiving
chemotherapy or radiotherapy were enrolled. The quantities of immune cells in the blood of the
subjects were determined before and after 6 weeks of cancer treatment, with either CCMH or a
placebo. CCMH significantly reduced the depletion of leukocytes (14.2% compared with 28.2%)
and neutrophils (11.0% compared with 29.1%). Analysis of the lymphocyte phenotype revealed
that the patients receiving the placebo had reduced CD4 lymphocytes and natural killer (NK)
cells than the CCMH-treated patients. Treatment with CCMH for patients receiving
chemotherapy and/or radiotherapy may improve their immune function, improving their ability
to fight off the cancer, as well as any secondary infections that could compromise their
treatment and their health. (c) 2009 John Wiley & Sons, Ltd.
Department of Pharmacy & Administrative Sciences, College of Pharmacy & Allied Health Professions, St.
John's University, Jamaica, NY., USA.
OBJECTIVES: To investigate the anticancer activities of a Chinese herb, Oldenlandia diffusa (Bai
Hua She She Cao). METHODS: The water extract of the raw herb Oldenlandia diffusa was used
in this study. The in vitro anti-proliferative activities of the extract were tested against eight
cancer cell lines and one normal cell line. Microscopic examination and DNA ladder analysis were
carried out to determine the pro-apoptotic effect of the extract. In vivo studies were carried out
to examine the anticancer activities of the extract using C57BL/6j mice bearing B16-F10 lung
metastasis. Oldenlandia diffusa extract was given at the dose level of 5 g raw material/kg on
Days 3-12 by oral gavage and the extent of lung metastases were examined on Day 14.
RESULTS: The extract exhibited a strong antiproliferative activity against all cancer cell lines
tested. The concentrations of growth inhibition at 50% (IC(50)) ranged from 7 to 25 mg raw
material/ml after 48-hour treatment. The extract had a very limited cytotoxicity (10%
inhibition) on the normal pancreatic cells even at the concentration of 50 mg/mL. Apoptosis in
B16-F10 cells after treatment with the extract was observed by microscopic examination and
DNA ladder assays. Oral administration of the herbal extract effectively reduced B16-F10 cell
growth in the lungs of C57Bl/j mice with a 70% reduction in lung metastases (p < 0.001).
CONCLUSIONS: Oldenlandia diffusa extract effectively inhibited the growth of all the eight
cancer cell lines and induced significant increase of apoptosis. The extract exhibited minimum
toxic effect on normal pancreatic cells. Furthermore, there was a significant inhibition of lung
metastases in the animal model with no noticeable adverse effects. The herb extract could be a
potential anticancer agent.
In vitro anticancer activity of twelve Chinese medicinal herbs.
Findings also show there were additional benefits to acupuncture treatment for breast cancer
patients, such as an increased sense of well being, more energy, and in some cases, a higher sex
drive, that were not experienced in those patients who underwent drug treatment for their hot
flashes.
"Our study shows that physicians and patients have an additional therapy for something that affects
the majority of breast cancer survivors and actually has benefits, as opposed to more side effects.
The effect is more durable than a drug commonly used to treat these vasomotor symptoms and,
ultimately, is more cost-effective for insurance companies," Eleanor Walker, M.D., lead author of
the study and a radiation oncologist at the Henry Ford Hospital Department of Radiation Oncology
in Detroit, said.
The reduction in hot flashes lasted longer for those breast cancer patients after completing their
acupuncture treatment, compared to patients after stopping their drug therapy plan.
Eighty percent of women treated for breast cancer suffer from hot flashes after being treated with
chemotherapy and/or anti-estrogen hormones, such as Tamoxifen and Arimidex. Although hormone
replacement therapy is typically used to relieve these symptoms, breast cancer patients cannot use
this therapy because it may increase the risk of the cancer coming back.
As a treatment alternative, patients are generally treated with steroids and/or antidepressant drugs.
These drugs, however, have additional side effects, such as weight gain, nausea, constipation and
fatigue. The antidepressant, venlafaxine (Effexor), a selective serotonin reuptake inhibitor, is one of
the most common drugs used to treat these hot flashes. However, many women decide against this
treatment choice because of potential side effects, including decreased libido, insomnia, dizziness
and nausea, or because they simply do not want to take any more medications.
The randomized clinical trial compared acupuncture treatment to venlafixine for 12 weeks to find
out if acupuncture reduced vasomotor symptoms in breast cancer patients receiving hormonal
therapy and produced fewer side effects than venlafaxine. The study involved 47 breast cancer
patients who received either Tamoxifen or Arimidex and had at least 14 hot flashes per week.
Results show that acupuncture reduces hot flashes as effectively as venlafaxine, with no side
effects, and also provides additional health benefits to patients.
Vorgeschichte:
Seit Beginn 2009 sehr erschöpft durch Überbelastung
gleichzeitig häufige Erkältungen und Sinusitiden ( 3x Antibiose)
-ruhte sich nicht aus und ging weiter arbeiten
Zustand zu Behandlungsbeginn:
steht vor Beginn der Chemotherapie: 3 x FEC und 3 x Doxetaxel
akute Candidasinfektion im Mund- Medikation Nystatin
schwere Erschöpfung
Adipositas: 85 Kg /170 cm
Schlaf: gut, keine Nachtschweiße, aber generell eher warm
Emotionen: hat Angst vor der Chemotherapie, glaubt an ihre Heilung, lässt keine
negativen Gedanken zu
Menstruation:
nimmt seit 3 Jahren die Pille (jetzt abgesetzt), keine Probleme
Labor nach 4. Chemo: Leuko: 5.5, Ery: 4.2, Hb 12,6, Thrombo 205
extreme Erschöpfung, antriebslos, bewegt sich nie, sitzt gerne, fühlt sich oft kalt
Labor nach der 2. Chemo: Leuko: 4.4, Ery: 4.5, Hb 12.4, Thrombo 407
Patientin fühlt sich sehr gut, kaum Nebenwirkungen, treibt Sport und hat ihre
Ernährung umgestellt, Blut stabil auch nach der 3. Chemo.
Nach Verabreichung der 4. Chemotherapie (Taxane): extreme Fatigue, Zittern am
ganzen Körper, geschwollener Zungenkörper, Magenschmerzen
Leuko: 1.8. Chemo wurde abgebrochen. In den nächsten Wochen beginnt die
Bestrahlung.