Beruflich Dokumente
Kultur Dokumente
a) tachycardia
b) palpitation
c) shock
d) fatigue
e) absent
b) megaloblastic anemia
e) aplastic anemia
d) the patient has also a disorder of the gastrointestinal tract ( eg. Ulcerative colitis )
e) megaloblastic anemia
5) Characteristic for megaloblastic anemia is :
a) MCV > 100..^3
c) Hypersegmented neutrophils
e) Leucopenia
b) blood loss
d) immune destruction of the acid and pepsin secreting cells of the stomach
b) reticulocytosis
d) hemosiderinuria
c) glucocorticoids
b) gallstones
c) pulmonary fibrosis
d) leg ulcers
e) cerebral hemorrhage
b) iron deficiency
e) hepatitis C virus
11) In the differential diagnosis between iron deficiency anemia versus anemia of chronic disease
which of the following are in favor of the latter :
a) low serum total iron-binding capacity
b) hemolysis
d) iron deficiency
b) intravenous immunoglobulins
c) plasma exchange
d) platelet transfusions
e) immune suppression
15) Acute disseminated intravascular coagulation ( DIC ) arises in some clinical circumstances
like :
a) acute promyelocytic leukemia
b) infection
d) Hodgkin´s disease
16) The appropriate level of anticoagulation independent of laboratory reagents for chronic oral
anticoagulants is obtained using :
a) APTT
b) bleeding time
c) PT
d) INR
e) D-dimer level
17) Adverse prognostic factors which influence outcome of therapy in AML are :
a) increased age at diagnosis
b) thrombocytopenia
d) hyperuricemia
e) neutropenia
a) TdT positive
b) PAS negative
c) myloperoxidase negative
b) age
c) immunephenotype
b) anemia
d) basophilia
b) megaloblastic anemia
c) polycythemia Vera
d) Idiopathic myelofibrosis
e) primary throbcytemia
b) thrombotic events
d) lymphadenopathy
b) Cyclophosphamide
c) Phlebotomy
d) Hydroxyreea
e) Aspirin
25) Poor prognostic signs in Idiopathic Myelofibrosis are :
a) unexplained fever
b) thrombocytopenia
c) anemia
d) severe hemolysis
e) hepatomegaly
b) severe thrombocytopenia
d) failure of glucocorticoids
e) refractory hemolysis
27) Differential diagnosis of Essential ( Primary ) Thrombocythemia is made by exlusion and the
following should be demonstrated :
a) the patient is not iron deficient and has normal to low red cell mass when iron sufficient or iron
repleted
b) Hydroxyureea
c) Interferon-a
d) Anagrelide
e) Vincristin
29) A 36 year old male patient recently diagnosed with Hodgkin´s disease with the following
findings after procedures for staging completed, has cervical lymph nodes, inguinal lymph node
enlargement, grade 1 splenomegaly, abdominal lymph node mass with a maximum diamter of 8
cm; he also complains of drenching night sweats, and a weight loss of 5 kg ( his initial weight was
80kg), bone marrow biopsy is normal. He is staged
a) 2 BX
b) 3 AX
c) 3 B
d) 4 BX
e) 3 BX
30) Diagnosis of Hodgkin´s disease is made on :
a) the symptom complex of lymph node enlargement and mediastinal adenopathy and fever
32) Which of the following statements is/are correct in regard to non-Hodkin´s Lymphoma :
a) NHL are usually disseminated at diagnosis
b) metastatic carcinoma
d) pseudolymphoma
e) Hodgkin´s disease
d) Hb < 11g/dl
b) Chromambucil
c) Hydrocyureea
d) Fludarabine
e) Cytosine- arabinoside
37) Diagnosis of Wladenstroms Macroglobulinemia is sustained by :
a) very high ESR
38) In which of the following situations can a diagnosis of multiple myeloma be made :
a) monoclonal serum lgG= 6.0 g/dl; lgA= 0.03 mg/dl
b) marrow plasmacytosis=17%, monoclonal lgA=1,6 g/dl, lgM= 0.06g/dl, lgG= 0.8 g/dl
39) Which of the following statements is/are true in regard to multiple myeloma ?
a) serum level of ß2-microglobulin correlates with myeloma cell mass
c) hypercalcemia
d) thrombocytopenia
e) anemia
41) Which of the following diseases are frequently associated with spleen enlargement :
a) immunologic thrombocytopenic purpura
d) thalassemia
e) idiopathic myelofibrosis