DRUG STUDY

DRUG NAME ACTION INDICATION CONTRAINDICATION ADVERSE NURSING

EFFECT CONSIDERATION

Aspirin >Thought to >Rheumatoid arthritis >Hypersensitivity to drug >GI: GI bleeding >Inflammatory

produce analgesia osteoarthritis, or other and in those with dyspepsia, GI condition, rheumatic
Acetylsalicsylic by inhibiting polyarthritic or NSAIDS-induced distress, Occult fever and thrombosis,
acid prostaglandin and inflammatory sensitivity reactions bleeding give aspirin in
other substances that conditions. deficiency or bleeding >Hematology: schedule rather than
>80mg, P.O, OD sensitize pain >Juvenile rheumatoid disorders such as Prolonged bleeding as needed.
after lunch receptors. Drug my arthritis. hemophilia, von time, leucopenia, >For patient
relieve fever by >Mild pain or fever willebtrand disease or thrombocytopenia. swallowing
acting on the >To prevent thrombosis telangiectasia. >Hepatic: Hepatitis difficulties, crush
hypothalamic heat- >To reduce risk of MI or >GI lesions, impaired >Skin: rash non-enteric-coated
regulating center unstable angina renal function, >Other: Angoiedema, aspirin and dissolve
and may exert it >Kawasaki syndrome hypoprothrombonemia, Reye symdrome, in soft food or liquid.
anti-inflammatory ( mucocutaneous lymph thrombotic hypersensititvy Give liquid
effect by inhibiting node syndrome ) h thrombocytopenic reaction. immediately after
prostaglandin and >Acute rheumatic fever purpura, or severe hepatic mixing because drug
other substances. In >To reduce risk impairment. will break down
10 doses, drug also recurrent transient rapidly.
appears to interfere ischemic attacks and >Febrile, dehydrated
with clotting by stroke or death in patient children can be
keeping a platelet at risk. developing toxicity
aggregating rapidly.
substance from >Monitor elderly
forming. patients closely
because that may is
more susceptible to
aspirin toxic effect.
>Monitor salicylate
Level.
Potassium chloride >Replace potassium >To prevent >Contraindicated in >CNS: Paresthesia of >Make surre powders
and maintains hypokalemia and sever patients with severe renal limbs. Listlessness, are completely
Kalium Durule potassium level. hypokalemia impairment with oliguria, confusion, weakness dissolve before
>Acute Mi anuria or azotemia; with or heaviness of limb, giving.
>P.O every 8 hr x 2 acute dehydration, heat flaccid paralysis. >Monitor renal
doses cramps, hyperkalemia, >CV: Postinfusion functions. After sh
hyperkalamic form of phlebitis, susurgery, don’t give
familial periodic paralisis, arrhythmias, heart drug until urine flow
or other conditions linked block, cardiac arrest, is established.
to extensive tissue ECG changes, >Many adverse
breakdown. hypotension. reactions may reflect
>Use cautiously in >GI: nausea and hyperkalemia.
patients with cardiac vomiting, abdominal >patients may be
disease or renal pain, diarrhea. sensitive to tarrazine
impairment. >Metabolic: in some of these
hyperkamemia products.
>Respiratory: >Don’t crush
respiratory paralysis. sustained-release
potassium products.

Omeprazole >Inhibits activity of >Symptomatic >Contraindicated in >CNS: asthenia, >dosage adjustment

acid (proton) pump gastroesophageal reflux patients htypersensitivity dizziness, headache. for those patient with
>20mg, P.O, OD and binds to disease. (GERD) to drug of its components. >GI: abdominal pain, hepatic impairment.
hydrogen-potassium without esophageal >Contraindicated in constipation, diarrh >drug increase its
adenosine lesions. patients with metabolic vomitinea, flatulence, own bioavailability
trophosphate at >Erosive esophangitis alkalosis and nausea and vomiting. with repeated doses.
secretory surface of and accompanying hypocalcemia. >Musculoskeletal: >Drug is unstable in
gastric parietal cells symptoms caused by >patients with barter Back pain gastric acid less drug
to block formation GERD. syndrome, hypokalemia >Respiratory: Cough, is lost to hydrolysis
of gastric acid. > Maintenance of and respiratory alkalosis. URTI. because drug
healing erosive >Long-term >Skin: rash increases gastric PH.
esophangitis. administration of
>Pathologic secretion. bicarbonate with calcium
>Duodenal Ulcer or milk can cause milk
>helicobacter pylori alkali syndrome.
infection and duodenal
 ulcer disease, to
eradicate H.pylori with
clarithromycin (dual
therapy)
>Short-term treatment of
active benign gastric
ulcer.
>Frequent heartburn.

Atorvastatin >Inhibits HMG-coA >Alone or as an adjunct >Contraindicated for >CNS: headache, >Use only after diet
Calcium reductase and rate- to lipid lowering those patients with active asthenia, insomnia. and other nondrug
limiting step in treatments such as LDL lover disease or >CV: peripheral therapies prove
>10mg, P.O, OD cholesterol aphresis, to reduce total unexplained persistent edema. ineffective. Patients
biosynthesis. and LDL cholesterol in elevation of transaminase >EENT: pharingitis, should follow a
patients with level. rhinitis, sinusitis. standard low-
homozygenous familial >History of liver disease >GI: abdominal pain, cholesterol diet
hypercholesterolemia. or heavy alcohol use. constipation, before and during
>To reduce the risk of >With hold or stop drug diarrhea, dyspepsia, therapy.
MI, Stroke, angina or in patients at risk for renal flatulence, nausea. >Single dose at any
revascularization failure cuased by >GU: UTI. time of day.
procedures in patients rhabdomyolysis resulting >Musculoskeletal: >Watch for signs of
with multiple risk factors from trauma, acute rhabdomyolysis, myositis.
for CAD but who don;t conditions that suggest arthritis, arthralgia,
yet have the disease. myopathy, and in major myalgia.
surgery, sever infections, >Respiratory:
hypotension, uncontrolled bronchitis
seizures, severe metabolic >Skin: rash
endocrine or electrolyte >Other: allergic
disorder. reaction, flulike
syndrome, infections.

Laxative >Intramural that >Chronic constipation; >Contraindicated in >CNS: dizziness, >Give drug at times
increases peristalsis preparation for patients hypersensitive to faintness, muscle that don’t interfere
Lilac by direct effect on childbirth, surgery or drug or its components weakness with with scheduled
smooth muscle of rectal bowel and in those with rectal excessive use. activities or sleep.
>30cc, P.O, OD, HS the stimulating the examination. bleeding, gastroenteritis, >GI: abdominal Soft, formed stools
 colonic intramural intestinal obstruction, cramps, sensation in are usually produced
plexus. Drug also abdominal pain, nausea rectum with 15-60 minutes after
promotes fluid and vomiting or other suppositories, nausea rectal use.
accumulation in symptoms of appendicitis and vomiting, >For patients
colon and small or acute surgical diarrhea, protein- suffered from
intestine. abdomen. losing enteropathy constipation
with excessive use. determine it first if
>Metabolic: patients has adequate
Alkalosis, fluid and fluid intake, exercise
electrolyte and diet.
imbalance, >Bisco-lax may
hypokalemia. contain tartrazine.
>Musculoskeletal:
Tetany

Plavix >Inhibits platelet >Treatment of patients at >Contraindicated with >CNS: headache, >Allergy to
aggregation by risk for ischemic events- allergy clopidogrel, active dizziness, weakness, clopidogrel, bleeding
Clopidogrel blocking ADP recent MI, recent pathological bleeding syncope, flushing. disorders, recent
receptors on ischemic stroke, such as peptic ulcer or >CV: hypertension, surgery, hepatic
>75mg, P.O, OD platelets, preventing peripheral artery te intracranial edema impairment, peptic
clumping of coronary disease. hemorrhage,lactation. >Dermatologic: rash, ulcer.
platelets. >Treatment of patients >Use cautiously with pruritis >Skin color, lesions,
with acute coronary bleeding disorders, recent >GI: Nausea, GI reflexes, orthostatic
syndrome. surgery, hepatic distress, constipation, BP, peripheral
impairment. diarrhea, GI bleed perfusion.
>Other: Increased
bleeding risk.