Pathophysiology is the study of the disturbance of normal mechanical, physical, and biochemical functions, either

caused by a disease, or resulting from a disease or abnormal syndrome or condition that may not qualify to be called a
disease. An alternate definition is "the study of the biological and physical manifestations of disease as they correlate
with the underlying abnormalities and physiological disturbances.”

Pathophysiology Clinical diagnosis w/ risk factors

1. Clinical diagnosis heading as figured in a schematic or flowchart form
- What system got involved/ affected?
2. Risk factors / predisposing factors
3. Main etiology involved / possible etiologies (CAUSE)
4. Examine further all the system in terms of gross /structural àmolecular activities or cellular level
(EFFECT))
5. Show all affected pertinent laboratory
6. Always end in the clinical signs and symptoms of the client

RISK FACTORS à ETIOLOGY (CAUSE) à PATHOLOGIC MANIFESTATIONS

(EFFECT ON ANATOMICAL-MOLECULAR LEVEL)
à PHYSIOLOGIC MANIFESTATIONS (EFFECT ON BODILY FINCTIONS)
à PERTINENT LABORATORY RESULTS à SIGNS & SYMPTOMS SEEN ON THE CLIENT

Pathophysiology Clinical diagnosis w/o risk factors

1. Clinical diagnosis as heading as figured in a schematic or flowchart form
- What system got involved/ affected?
2. Main etiology involved / possible etiologies (CAUSE)
3. Examine further all the system in terms of gross /structural àmolecular activities or cellular level (EFFECT)
4. Show all affected pertinent laboratory
5. Always end in the clinical signs and symptoms of the client
ETIOLOGY (CAUSE)à PATHOLOGIC MANIFESTATIONS
(EFFECT ON ANATOMICAL-MOLECULAR LEVEL)
à PHYSIOLOGIC MANIFESTATIONS (EFFECT ON BODILY FINCTIONS)
à PERTINENT LABORATORY RESULTS à SIGNS & SYMPTOMS SEEN ON THE CLIENT

Pathophysiology : Causative organism

1. Start with primary etiology: causative organism (CAUSE)
2. Mode of transmission
3. Anatomical and molecular consequences: (EFFECT) -abnormal bodily function (pathologic and physiologic)
4. Pertinent signs & symptoms of the client

CAUSATIVE ORGANISM à MODE OF TRANSMISSION à PATHOLOGIC MANIFESTATIONS

(EFFECT ON ANATOMICAL-MOLECULAR LEVEL)
à PHYSIOLOGIC MANIFESTATIONS (EFFECT ON BODILY FINCTIONS)
à SIGNS & SYMPTOMS SEEN ON THE CLIENT

Pathophysiology: Main etiology

1. Start with main etiology (CAUSE)
2. Consequences: Pathologic/ Physiologic (EFFECT)
- organ/s involved.
- blood vessels/ nerves affected
3. Pertinent signs & symptoms of the client

ETIOLOGY (CAUSE)à PATHOLOGIC MANIFESTATIONS

(EFFECT ON ANATOMICAL-MOLECULAR LEVEL)
à PHYSIOLOGIC MANIFESTATIONS (EFFECT ON BODILY FINCTIONS) à SIGNS & SYMPTOMS SEEN
ON THE CLIENT