Beruflich Dokumente
Kultur Dokumente
Recessive Lethality
Agouti yellow is not an example of recessive lethality in real life
Manx mutation: manx allele is a loss of funciton allele and wt cats are homozygous for an
allele, heterozygous make half the amount of functional product, and homozgyous for the
mutation don't make the product at all
Semidominant mutation
Little m is semidominant to the wildtype in the heterozygous
Recessive lethality: homozygosity in a single locus instead of being a double mutant
Different from synthetic lethality which involves two different genes
Manx phenotype is similar to what we see in snap dragon (red flower, pink flower, white
flower), same idea of semidominance