Beruflich Dokumente
Kultur Dokumente
DOI 10.1007/s13555-017-0197-y
CASE REPORT
. . .
Nathalie Krecke´ Sigrun Smola Thomas Vogt Cornelia Sigrid Lissi Mu¨ller
ABSTRACT
S. Smola
Institute of Virology, Saarland University Medical
INTRODUCTION
Fig. 1 Hypopigmented, shiny maculae within a tattoo on the left upper forearm
(Fig. 1). The role of b-HPV types in terms of skin addition to multiple clusters of keratinocytes with
carcinogenesis in the normal population is as yet vacuolar cytoplasm (Fig. 2a, b). Altogether, it appeared
unknown [5, 7–10, 13]. as a viral lesion even though there was no
akanthopapillomatosis. An immuno-histochemical
analysis in order to detect HPV by use of the
monoclonal murin anti-HPV antibody (Clone K1H8)
CASE PRESENTATION was initiated (M3528, dilution of 1:50; Agilent
Technologies/Dako). This aHPV-antibody is
specifically immunore-active on formalin-fixed
paraffin-embedded HPV-infected tissue when HPV
We present the case of a 48-year-old male patient with
subtypes 1, 6, 11, 16, 18, 31, 33, 42, 51, 52, 56 and 58
the diagnosis of plane verrucae vulgares with
are present [1]. This stain distinguished nearly all of
intralesional proof of b1-HPV type 47 on the edge
the corneocytes in the stratum corneum in a nuclear
areas of his tattoos on both forearms (Fig. 1). The
pattern, while a few nuclei showed reactivity in the
tattooing took place 20 years ago, whereas the first
stratum granulosum (Fig. 3). In
cutaneous lesions had been noticed by the patient only
8 years ago. Histologically, a granular hyperparaker-
atosis and hypergranulosis were observed in
Fig. 2 HE stain of lesional skin. a Original magnification 9200. Granular hyperkeratosis and hyperparakeratosis with
cluster of keratinocytes with vacuolar cytoplasm, b original magnification 9400
Dermatol Ther (Heidelb) (2017) 7:549–554 551
DISCUSSION
ACKNOWLEDGEMENTS
anti-oxidative effect of the sinecatechines pre-sent in No funding or sponsorship was received for
the leaves of green tea, while antipro-liferative and publication of this article. The article processing
antiviral actions should also be considered [43, 44]. charges were funded by the authors. All named authors
meet the International Committee of Medical Journal
Editors (ICMJE) criteria for authorship for this
manuscript, take responsi-bility for the integrity of the
work as a whole, and have given final approval for the
version to be published.
CONCLUSIONS
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