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BRAIN
Part of the central nervous system (CNS) that lies within
the cranial vault—the encephalon
Its surface is convoluted and exhibits gyri and sulci
Covered by three connective tissue membranes, the
meninges.
Surrounded by cerebrospinal fluid (CSF)
One of the largest organs in body
Weight
New-born: 350 g
Men: 1,600 g (3.5 lbs)
Women: 1,450 g (3.2 lbs)
One of most metabolically active organs in body
comprises only 2% of total body weight it yet
Gets 15% of blood
Consumes 20% of our oxygen need at rest (more
BRAIN: CEREBRUM/CEREBRAL HEMISPHERES
when mentally active)
Blood flow and O2 increase to active brain areas Largest portion of brain - Constitutes 60% of brain mass
1 – 2 mins interruption of blood flow may impair brain Takes part in: thought, creativity, communication
cells It is formed of two cerebral hemispheres by a median
> 4mins without oxygen permanent brain damage longitudinal fissure, connected to each other by
Corpus callosum
Right and left cerebral peduncles: connected to
DIVISIONS OF BRAIN
upper part of the brain stem
ANATOMICAL DIVISIONS
Anterior, posterior & habenular commissures
I. Cerebrum
Made up mostly of grey matter
Right Hemisphere
Left Hemispheres
FUNCTIONS OF CEREBRAL CORTEX
II. Diencephalon
1. Consciousness: brain stem-reticular formation,
III. Cerebellum
frontal, temporal and deep structures of cerebrum
IV. Brainstem
2. Use of language: speech center present in frontal
Midbrain
and temporal lobes
Pons
3. Emotions: frontal and temporal lobes (limbic
Medulla
system)
4. Memory: frontal and temporal lobes
FUNCTIONAL AREAS
5. Orientation, thinking and intelligence: frontal lobe
I. Motor Areas
II. Sensory Areas
EXTERNAL FEATURES
III. Higher Functions
Each cerebral hemisphere has
Three Surfaces
1. Lateral (superolateral) surface
2. Medial surface
3. Inferior surface
Three Poles
1. Frontal Pole: at the anterior end of the
frontal lobe
2. Temporal Pole: at the anterior end of the
temporal lobe
Lateral Ventricle
The cavity of the cerebral hemisphere
Communicate with the third ventricle via the two
interventricular foramina (of Monro)
INTERNAL CAPSULE
Thick lamina of white matter made up of projection
fibers which pass to and from the cerebral cortex
It is continuous superiorly with the corona radiata,
and inferiorly with pedunculi of midbrain
INTERNAL STRUCTURE/COMPONENTS Parts
Gray Mater (Outer) 1. Anterior limb
Composed of nerve cells (cerebral cortex). The cells 2. Genu
of each area have specific functions 3. Posterior limb
Sulcus Separates
Inferior frontal
gyrus in Motor center of
Area (45)
dominant writing.
hemisphere
Inferior frontal
Brocca's Area gyrus in Motor center of
(44) dominant speech
hemisphere
Higher center of
Prefrontal memory,
FRONTAL LOBE Areas (9, 10, Anterior pole orientation,
Sulci 11 & 12) thinking and
Sulci Location intelligence
Gyri
Important Functional Areas
Gyri Location
Area Site Function
Lies between the lateral sulcus
Superior temporal Posterior medial
and the superior temporal Primary Visual sensory area
gyrus part of occipital
sulcus visual sensory (perception of
Lies between the superior and lobe (surrounds
Middle temporal gyrus area (17) visual impulses)
inferior temporal sulcus calcarine sulcus)
Lies below the inferior Secondary
Inferior temporal gyrus Anterior to area Visual association
temporal sulcus (psychic)
17 in dominant area (Recognition
visual area
Important Functional Areas hemisphere & recall of image)
(18, 19)
Area Site Function
Primary
Superior temporal Auditory sensory
auditory (area
gyrus area
41,42)
Sensory Auditory
Superior temporal
speech area or association area
lobe of dominant
Wernicke's (recognition &
hemisphere
center (area recall of sounds)
HISTOLOGY
1. Molecular or Plexiform
Composed of horizontal cells of Cajal& Golgi
type II
2. Outer / External Granular Layer
Small pyramidal or triangular cells whose BRAIN: DIENCEPHALON
dendrites terminate on the molecular layer Paired structure
3. Outer / External Pyramidal Layer Located between the telencephalon and mesencephalon
Composed of typical well-formed pyramidal and between the interventricular foramina and the
neurons posterior commissure
Two sub layers Continuous with the rostral part of the midbrain
Superficial layer of medium sized Forms the lateral wall of the 3rd ventricle
pyramidal cells: horizontal Myelinated Receives the optic nerve (CN II)
fibers Contains dozens of nuclei of gray matter
Deep layer of large pyramidal cells
4. Internal Granular Layer DIVISIONS
Composed of stellate cells On the medial surface, the diencephalon is
Interspersed within the layer are horizontal subdivided, by hypothalamic sulcus into
myelinated fibers forming external band of I. Dorsal part
Baillarger (thalamo-cortical ramifications) 1. Epithalamus
5. Internal Pyramidal or Ganglion Layer 2. Thalamus
Giant Pyramidal cells of Betz (origin of the II. Ventral part
pyramidal tract) 1. Hypothalamus
2. Subthalamus
1. EPITHALAMUS Functions
Relatively small part, located in most caudal and 1. Autonomic function
dorsal region ANS is regulated by hypothalamic nuclei.
Lies immediately rostral to superior colliculus o Anterior hypothalamus excitatory
Consists of effect on the parasympathetic nervous
Pineal gland system
Habenular nuclei o Posterior hypothalamus excitatory
effect on the sympathetic nervous
Pineal Gland system
An endocrine organ 2. Temperature regulation
Synthesizes melatonin Anterior hypothalamus
Controls o Helps regulate and maintain body
o Sleep/awake cycle temperature
o Regulation of onset of puberty o Destruction causes hyperthermia
Posterior hypothalamus
Habenular Nuclei o Helps produce and conserve heat
Located in habenular triangle (area in the o Destruction causes the inability to
posterior part of the diencephalon, just anterior thermoregulate
to pineal gland) 3. Water balance regulation
Have connections with limbic system ADH controls water excretion by the
Serves autonomic function and emotional kidneys
drives 4. Food intake regulation
Ventromedial nucleus
2. THALAMUS Lateral hypothalamic nucleus
Egg shaped, large mass of grey matter o Hunger or feeding center
Two large lobes of gray matter (over a dozen o Destruction causes starvation and
nuclei) emaciation
Laterally enclose the 3rd ventricle
Separated from hypothalamus by hypothalamic 4. SUBTHALAMUS
sulcus Most of the subthalamus is just a rostral extension
Gateway to cerebral cortex: every part of brain that of the midbrain
communicates with cerebral cortex relays signals It contains one nucleus, subthalamic nucleus
through a nucleus in the thalamus (e.g. Certain Plays a role in motor control and is interconnected
nucleus for info from retina, another from ears, etc.) with the basal ganglia
Boundaries
Anterior: interventricular foramen BRAIN: CEREBELLUM
Posterior: free pole of the pulvinar Largest part of hind brain
Dorsal: free surface underlying the fornix and Called “silent area”
the lateral ventricle Weight: 150 g
Ventral: plane connecting the hypothalamic Develops from the alar plates (rhombic lips) of the
sulci metencephalon
Medial: third ventricle Located infratentorially within the posterior fossa and
Lateral: posterior limb of the internal capsule lies between the temporal and occipital lobes and the
brainstem
3. HYPOTHALAMUS
Forms inferolateral wall of 3rd ventricle ANATOMICAL DIVISIONS
Many named nuclei Two Hemispheres
Vermis
FUNCTIONS
Fissures 1. Maintenance of posture and balance
1. Primary fissure 2. Maintenance of muscle tone
2. Horizontal fissure (pre-pyramidal fissure) 3. Coordination of voluntary motor activity
3. Posterior fissure (posterolateral fissure)
CEREBERLLAR NUCLEI
Lobes Masses of grey scattered in white matter
1. Anterior lobe Cerebellar
Location Features
2. Posterior lobe Nuclei
3. Flocculo-nodular lobe Most prominent
Fastigial Near the
Largest in primates
nucleus middle line
Notches Nucleus of Neocerebellum
1. Anterior cerebellar notch: Pons and Medulla Lateral to Nucleus of
Globose
2. Posterior cerebellar notch: lodges the Falx cerebelli Fastigial Paleocerebellum
nucleus
nucleus Flexor muscle tone
Below the Oval shaped
Emboliform
Fastigial Nucleus of
nucleus
nucleus paleocerebellum
Nucleus of
Dentate Lateral to all
Archicerebellum
nucleus other nuclei
Extensor muscle tone
HISTOLOGY
Has three layers
1. Molecular layer
Most superficial, underlying the pia mater
Contains stellate cells, basket cells, and the
dendritic arbor of the Purkinje cells
2. Purkinje cell/Ganglionic layer
Lies between the molecular and the
granule cell layers
Conspicuous cell body and their dendrites
are highly developed, assuming the aspect
of a fan
3. Granule layer
Deepest layer overlying the white matter
Contains granule cells, Golgi cells, and Formed by the Cerebral Peduncles (Crus
cerebellar glomeruli Cerebri)
A cerebellar glomerulus consists of a These consist of the converging cerebral crura
mossy fiber rosette, granule cell dendrites, (the most anterior parts of the cerebral
and a Golgi cell axon peduncles), which are separated from each
other by the interpeduncular fossa
Each peduncle consists of three parts - Crus
Cerebri, Substantia Nigra and Tegmentum
Oculomotor (III) nerves emerge from the walls
of the interpeduncular fossa
INTERNAL ANATOMY
CEREBELLAR DYSFUNCTION
Includes the following triad
Hypotonia - loss of the resistance
Dysequilibrium - loss of balance characterized
by gait and trunk dystaxia
Dyssynergia - loss of coordinated muscle
activity
PARTS
An imaginary line passing from side to side
through the Cerebral Aqueduct divides the
midbrain into,
1. Anterior/Ventral Surface (Tegmentum)
2. Posterior/Dorsal Surface (Tectum)
1. Anterior/Ventral Surface
CAUDAL MIDBRAIN AT THE LEVEL OF INFERIOR It has extra-pyramidal motor function, concerned
COLLICULUS with movements
Inferior Colliculus Lesion of pars compacta leads to Parkinson’s
Amass of grey matter which receives ascending disease. It is due to absence of dopamine into basal
auditory pathway, that run in lateral lemniscus to ganglia, this is manifested by a mask face, resting
end in inferior colliculus. Its the centre of hearing tremors, rigidity of muscles and a shuffling gait
reflex
Crus Cerebri
Cerebral Aqueduct Lies ventral to Substantia Nigra
Runs ventral to colliculi, and surrounding by area Consists entirely of descending cortical efferent
of grey matter, the peri-aqueductal (or central grey) fibers
50% of Crus consists of pyramidal tract, consists of
Trochlear Nucleus cortico-bulbar + cortico-spinal fibres which traverse
Lies ventral to peri-aqueductal grey pons, down to medullary pyramid and spinal cord
On either side of corticobulbar & corticospinal
CAUDAL MIDBRAIN AT THE LEVEL OF INFERIOR fibres, crus cerebri contains cortico-pontine,
COLLICULUS temporo-pontine + fronto-pontine fibres
Medial Longitudinal Fasciculus
A well-defined bundle of fibres lies on each side of ROSTRAL MIDBRAIN AT THE LEVEL OF SUPERIOR
median plane in midbrain tegmentum COLLICULUS
It extends throughout the brain stem, and descends Superior Colliculus
into spinal cord Lies in upper part of tectum of midbrain
It helps in control of gaze by coordination of eye, It is a Centre of visual reflexes
head & neck movements
Pretectal Nucleus
Decussation of Superior Cerebellar Peduncles (Brachium Lies close to superio-lateral part of Superior
Conjunctivum) Colliculus
Fibres of each peduncle cross to opposite side, It has connections with parasympathetic nucleus of
forming decussation in the central part of Oculomotor nerve (Edinger-Westphal nucleus) to
tegmentum control smooth muscles of eye (sphincter pupillae)
and to mediate pupillary light reflex
Medial Lemniscus
It is a band of ascending fibers carrying Oculomotor Nucleus
proprioceptive & fine touch sensation from Lies ventral to peri-aqueductal grey
opposite side of body Efferent fibers emerge from the medial surface of
It is the upward continuation of gracile & cuneate Crus Cerebri as Oculomotor nerve to supply
tracts of opposite side extraocular muscles of eye (except SO + LR)
It lies in tegmentum, posterior to substantia nigra
Red Nucleus
Substantia Nigra It is a large mass of grey matter lies in tegmentum
It is a large motor nucleus, lies at the most ventral of rostral midbrain
part of midbrain tegmentum It is involved in motor control
It contains subdivision part, the pars compacta,
which consists of pigmented, melanin-containing
neurons that synthesize dopamine as their BRAIN: PONS
transmitter
Situated between the medulla (below) and midbrain
It projects to caudate nucleus + putamen of basal
(above)
ganglia in the forebrain
Lies in the posterior cranial fossa on the clivus, anterior
to the cerebellum
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NEURO ANATOMY & PHYSIOLOGY 10
Brain and Spinal Cord
Its axons form the motor root of Trigeminal nerve It is a band of ascending fibres carrying hearing
which passes along Mandibular nerve sensation from both ears (mainly from opposite
side)
Lateral in position
It receives afferent touch sensation from face & Spinal Lemniscus
It sends efferent fibres, cross to opposite side to join It is a band of ascending fibers
axons of spinal nucleus of trigeminal, forming Carrying pain, temperature & light touch from
thalamus
Trigeminal Lemniscus
Lies in the rostral part of pons, forming lateral walls It is a band of ascending fibers carrying superficial
BRAIN: MEDULLA
Most inferior part of Brain Stem
Become Spinal cord at the level of Foramen Magnum
Contains autonomic centres that regulate respiration,
circulation, and gastrointestinal motility
Extends from the pyramidal decussation to the inferior Another elevation lateral to cuneate tubercle;
pontine sulcus Tuber Cinereum is formed by the spinal nucleus
Gives rise to cranial nerves—CN IX to CN XII of the trigeminal nerve
The nuclei of CN V and CN VIII extend caudally into
the medulla Upper Open Part
Connected to the cerebellum by the inferior cerebellar Forms the lower part of the floor of the 4th
peduncle ventricle
Presents many features - median sulcus,
EXTERNAL FEATURES hypoglossal and vagal triangles, vestibular
Divided into right and left symmetrical halves by areas, area postrema, stria medullaris
the anterior median fissure and posterior median
sulcus INTERNAL STRUCTURE
Studied at three levels
Ventral Part
Pyramids 1. At the Level of Decussation of Pyramids
Are two elongated elevations, one on either Passes through the inferior half of the medulla
side of the anterior median fissure Nucleus Gracilis and Nucleus Cuneatus appear as
Formed by the underlying corticospinal narrow strip-like projections from the posterior
(pyramidal) fibres aspect of the central grey matter
Olives Apex of posterior horn form the nucleus of the
Are oval elevations, posterolateral to the spinal tract of the trigeminal nerve
Pyramids Decussation of Pyramidal tracts
Formed by an underlying mass of grey matter Most important feature of medulla at this level
called Inferior Olivary Nucleus About 75% fibres of pyramidal tract cross the
Inferior Cerebellar Peduncles midline to get to the lateral white column of
Are thick bundles of fibres lying posterolateral the other side of the spinal cord in the place
to the Olive where they run downward as the lateral
Attach the medulla with the cerebellum corticospinal tract. In doing this, the anterior
Rootlets of the Hypoglossal nerve horns are detached from the central grey
Seen between the pyramid and the olive matter
Rootlets of the 9th, 10th and 11th (cranial part) Every detached anterior horn breaks up to
cranial nerves create the spinal nucleus of the accessory nerve
Seen between olive and inferior cerebellar and the supraspinal nucleus of the 1st cervical
peduncle. nerve
Reticular formation - Diffuse zone with a network
Dorsal Part of fibres and scattered nerve cells in the lateral
Divided into two parts white column adjacent to the nucleus of the spinal
1. Lower Closed tract of the trigeminal nerve
2. Upper Open
CONTENTS
1. Epidural space
2. Spinal meninges
3. Spinal cord with its nerve roots
Epidural Space
Lies between the spinal dura and the periosteum
lining the vertebral canal
Filled with loose areolar tissue, semiliquid fat,
BRAIN: RETICULAR FORMATION spinal arteries and a network of veins—the internal
A diffuse ill-defined mass of nerve cell clusters and vertebral venous plexus
interlacing nerve fibres occupying the entire core of the
brainstem Spinal Arteries
Formed by neurons & processes left over after well- These are segmental arteries
defined named nuclei & pathways Arise from ascending cervical and deep
Phylogenetically, old system cervical arteries in the cervical region, from
Located in the brain stem posterior intercostal arteries in the thoracic
Comprises of medullary, pontine & midbrain region, from lumbar arteries in the lumbar
Poly synaptic region, and lateral sacral arteries in the sacral
Has both ascending and descending components region
Extends cranially to the diencephalon and caudally to They enter the vertebral canal through
the spinal cord intervertebral foramina along the spinal nerve
Receives data from most of the sensory systems of the roots
body and relay them to all the levels of the neuraxis They supply spinal cord, its nerve roots,
Has important role in maintenance of sleep–wake cycle, meninges, and the surrounding bones and
level of consciousness, and alertness or mutism ligaments
Has localized cell groups called reticular nuclei in
certain regions Internal Vertebral Venous Plexus
It is a network of veins extends throughout the
Functional Components length of the vertebral canal
1. Ascending Reticular Activating System (ARAS) These veins correspond to the dural venous
2. Descending Reticular System (DRS) sinus within the cranial cavity and are
continuous with them through the foramen
Cauda Equina
Leash of lumbar (except L1), sacral, and coccygeal
nerve roots around the filum terminale in the pool
of CSF
It is so named because the lower end of the spinal
cord along with the afore mentioned structures
resembles the tail of a horse (cauda = tail, equina =
SPINAL CORD horse)
EXTERNAL FEATURES
Fissures and Sulci
1. Anterior Median Fissure
Deep anterior midline groove in which the
anterior spinal artery is found superficially
Anterior median fissure and posterior median Divided into symmetrical right and left comma
septum divide the entire mass of white matter into shaped masses, which are connected across the
two lateral halves midline by a transverse grey commissure
The band of white matter lying in front of anterior Divided into cytoarchitectural areas called Rexed
gray commissure is called Anterior White laminae, expressed with Roman numerals
Commissure Divided into three horns or cell columns on each
Each half of the white matter is divided by the side
fibers of anterior and posterior nerve roots into 1. Anterior horn
three white columns or funiculi 2. Lateral horn
Lies between the anterior 3. Posterior horn
Anterior or Ventral median fissure on one side Part of grey matter anterior to spinal canal
White Column / Anterior and anterior nerve root and Anterior grey commissure
or Ventral Funiculus anterior gray horn on the Part to grey matter posterior to spinal canal
other side Posterior grey commissure.
Lies between the anterior Part of white matter between the anterior median
nerve root and anterior gray sulcus and the anterior grey commissure
Lateral White Column / horn on one side and Anterior white commissure
Lateral Funiculus posterior nerve root and
posterior gray horn on the
other side
Posterior or Dorsal Lies between the posterior
White Column / nerve root and posterior gray
Posterior or Dorsal horn on one side and
Funiculus posterior median septum on
the other side
Gray Matter
Found toward the center of the spinal cord
Butterfly or H-shaped that varies according to spinal
cord level
Contains a central spinal canal
ANATOMICAL ORGANIZATION
Ascending pathway consists of 3 neurons
Neuron Origin Supply
2. Descending/Motor/Efferent
Deliver information to the periphery
1. Fasiculus gracilis
Posterior
2. Fasiculus cuneatus
funiculus
3. Comma Tract of Schultze
Types
Type Tract
Pyramidal tracts
First tracts to be
found in man 1. Anterior corticospinal tract
Concerned with 2. Lateral corticospinal tract
voluntary motor
activities
Pyramidal Tracts
Extrapyramidal tracts
Ans: B .Projection
Ref: Gray’s Anatomy 38/e, p. 1176
Ans: B. Vertical
Ans: C. Inferior frontal lobe
8. Lesion of medial temporal lobe is associated with
A. Auditory amnesia 13. Auditory area is situated in
B. Agnosia A. Middle frontal gyrus
C. Visual amnesia B. Inferior frontal gurus
D. Alexia C. Superior parietal lobule
D. Superior temporal gyrus
Ref: Gray’s Anatomy 38/e, p. 1164 - Medial temporal lobe lesion is a/w auditory
amnesia
- Broca’s area is localized in inferior frontal lobe,
17. Visual area (are 17) lies in the frontal eye motor field is 6,8,9, pre or
A. Temporal lobe secondary motor area is 4
B. Occipital lobe
C. Parietal lobe 22. Following is true about hippocampus except
D. Frontal lobe A. It forms a projection in the inferior horn of lateral
ventricle of brain
Ans: B. Occipital lobe B. Its ventricular surface is covered by a layer of nerve
Ref: Essentials of Human Anatomy, 3/e, A.K Datta vol fibres called as alvenus
4, p.59-61 fig 6.11 C. Microscopically hippocampal cortex is made up of
six layers
18. Wernicke’s speech area is present in the D. Efferent fibres of hippocampus are called as
A. Superior temporal gyrus formnix
B. Middle frontal gyrus
C. Inferior frontal gyrus
D. Superior parietal lobule Ans: C. Microscopically hippocampal cortex is made up
of six layers
Ans: A. Superior temporal gyrus Ref: Essentials of Human Anatomy, 3/e, A.K Datta vol 4,
Pulvinar nuclei, Intralaminar nuclei, Anterior D. Fibres leaving the stria terminalis and reaching
(Rostral) nuclei. habenular nuclei are called as stria medullaris
- Ventral posterior nucleus of thalamus include thalami
medial (not lateral) lemniscus,
spino/solitario/& trigemino - thalamic tracts. Ans: C. Throughout the course, it is related lateral to the
caudate nucleus
Ref: Essentials of Human Anatomy, 3/e, A.K Datta vol
7. Hippocampal formation includes all except 4, p.88-89
A. Dentate gyrus
B. Subicular complex
C. Amygdaloid nucleus 10. Cavity of diencephalon is
D. Entorhinal cortex A. Lateral ventricle
B. Fourth ventricle
C. Cerebral aqueduct
Ans: C. Amygdaloid nucleus
D. Third ventricle
Ref: Gray’s 40/e p 349-51
Ans: D. Third ventricle
Explanation:
Ref: Essentials of Human Anatomy, 3/e, A.K Datta vol
- Hippocampal formation includes 4, 3/e, p.98
parahippocampal gyrus, hippocampus, dentate
gyrus, subicular complex and entorhinal cortex
mn- Phd in subject ENT
11. Thalamus is the largest relay centre for all sensory
- Alveus, fimbria & fornix, mammilo thalamic
inputs EXCEPT
tract body and anterior nuclear group of
A. Touch
thalamus and stria terminalis form the
B. Olfaction
connecting pathays of limbic system.
C. Hearing
D. Pressure
8. Following is true about Amygdaloid body except
A. It belongs to archistriatum
B. It is situated near the temporal pole of cerebrum Ans: B. Olfaction
C. It is anterior to hippocampus and in close proximity Ref: Snell’s Clinical Neuroanatomy, 5/e, p. 375
with the tail of caudate nucleus
D. Inferiorly it is related to anterior part of lentiform
nucleus 12. Followings is true about medial geniculate body
EXCEPT
A. It is situated posteriorly on the ventrolateral surface
Ans: D. Inferiorly it is related to anterior part of of thalamus
lentiform nucleus B. It receives fibres from medial lemniscus
Ref: Essentials of Human Anatomy, 3/e, A.K Datta vol C. It has a relay station on the auditory pathway
4, p.88,79 D. Fibres arising in it form acoustic radiations, which
pass through sublentiform part of internal capsule
of brain.
Ans: D. Efferent from its form the optic radiations, 17. Following nucleus of hypothalamus is mainly
which pass through posterior limb of internal capsule of responsible for secretion of antidiuretic hormone
brain to reach the parietal cortex A. Preoptic
Ref: Essentials of Human Anatomy, 3/e, A.K Datta vol B. Supraoptic
4, p.68 C. Posterior
D. Lateral
- Purkinje cells axon are the only output from the A. Vestibule cerebellar
cerebellar cortex, generally pass to deep nuclei. B. Oliver cerebellar
C. Spino cerebellar
D. Ponto cerebellar
3. Following part of vermis of cerebellum belongs to
neocerebellum
A. Lingual Ans: D. Pontocerebellar
B. Central lobule 8. Middle cerebellar penducle transmits…fibres
C. Culmen A. Ponto cerebellar pathway
D. Declive B. Tectospinal pathway
C. Spino cerebellar pathway
Ans: D. Declive D. Middle cerebellar pathway
Ref: Essentials of Human Anatomy, 3/e, A.K Datta vol
4, p. 161 fig 8.3
Ans: A. Pontocerebellar
6. Structures not passing through inferior cerebellar 10. Vestibulocerebellar tract terminates in the… of
peduncle cerebellum
A. Pontocerebellar A. Flocculus
B. Cuneocerebellar B. Lingual
C. Anterior spinocerebellar C. Nodulus
D. Posterior spinocerebellar D. Uvula
E. A& C E. A, C & D
Ans: A. Culmen
Ref: Essentials of Human Anatomy, 3/e, A.K Datta vol Ans: A. Olivocerebellar
4, p. 162 Ref: Essentials of Human Anatomy, 3/e, A.K Datta vol
4, p. 164
Ans: A. Olivocerebellar
Ref: Essentials of Human Anatomy, 3/e, A.K Datta vol Ans: B. Cerebello – vestibular
4, p. 164 Ref: Essentials of Human Anatomy, 3/e, A.K Datta vol
4, p. 169
13. Following tracts pass through the superior cerebellar
peduncle EXCEPT
A. Hypothalamocerebellar 17. Following is true about substantia nigra except
B. Dorsal spinocerebellar A. It is a neuromelanin containing pigmented
C. Ventral spinocerebellar substance present in midbrain
D. Tectocerebellar B. It is connected with cerebral cortex spinal cord and
hypothalamus
C. It has connections with ventral posterior nucleus of
Ans: B. Dorsal spinocerebellar
thalamus
Ref: Essentials of Human Anatomy, 3/e, A.K Datta vol
D. Lesions of dopaminergic nigro-striated fibres cause
4, p. 167-69
Parkinson’s disease.
Ans: B. Pons
Ans: A. Rhomboid fossa forms the floor
Ref: Essentials of Human Anatomy, 3/e, A.K Datta vol
Ref: Gray's Anatomy 39/e p. 291
4, p. 131
Explanation:
2. Following is true about cerebello medullary cistern C. There is contralateral limb paralysis
D. There is ipsilateral paralysis of tongue muscles
EXCEPT
because of involvement of hypoglossal nerve
A. It lies between clivus and anterior surface of
medulla oblongata
B. It contains posterior inferior cerebellar artery
Ans: A. It is caused because of thrombosis of
C. It can be tapped by a needle passing through the
medullary branches of AICA
posterior atlanto – occipital membrane
Ref: Essentials of Human Anatomy, 3/e, A.K Datta vol
D. Foramen of Magendie communicates with it
4, p. 156
Ans: A. It lies between clivus and anterior surface of 6. Following is true about ‘lateral medullary syndrome’
medulla oblongata EXCEPT
Ref: Essentials of Human Anatomy, 3/e, A.K Datta vol A. It is caused by thrombosis of medullary branches of
4, p. 193 posterior inferior cerebellar artery
B. Lateral and dorsal parts of medulla oblongata are
involved
3. Following white matter fibres are present in the C. Loss of function of nucleus ambiguous causes
paramedian area in medulla oblongata at the level of ipsilateral paralysis of vocal folds as well as palatal
inferior olivary nucleus EXCEPT and pharyngeal muscles
A. Medial lemniscus D. Lesion of spinal lemniscus causes ipsilateral loss of
B. Tectospinal tracts pain and temperature sensations
C. Olivocerebellar tracts
D. Medial longitudinal fasciculus
Ans: D. Lesion of spinal lemniscus causes ipsilateral
loss of pain and temperature sensations
Ans: C. Olivocerebellar tracts Ref: Essentials of Human Anatomy, 3/e, A.K Datta vol
Ref: Essentials of Human Anatomy, 3/e, A.K Datta vol 4, p. 155
4, p. 127
A. Nucleus pulposus is a remnant of notochord Ref: Essentials of Human Anatomy, 3/e, A.K Datta vol
B. Rich vascular supply 4, p. 203
C. Prolapsed is most common in lumbosacral region
D. None of the above 4. Spinal cord is composed off
A. Grey matter in the centre
B. White matter in the centre
Ans: B. Rich vascular supply
C. Grey matter in the periphery
Ref: Gray's 38th/e P-512-513
D. B and C
Explanation:
Ans: A. Grey matter in the centre
Except for the periphery, the intervertebral disc is
Ref: Gray’s Anatomy 38/e, p. 977
avascular structure.
A. Motor tracts
B. Sensory tracts
1. Following tract carries pain sensation C. Mixed tracts
A. Posterior spinocerebellar D. Sympathetic
B. Anterior spinocerebellar
C. Lateral spinothalamic
D. Vestibulospinal Ans: A. Motor tracts
Ref: Gray’s Anatomy 39/e, p. 320
Explanation:
CLASSIFICATION OF TRACTS