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Teguh Triyono

Faculty of Medicine Universitas Gadjah Mada/ Sardjito Hospital


Yogyakarta
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Recruit
Screen Donor Pre-transfusion testing Issue

Infectious Disease Test Medical


Decission to transfuse Monitor & Evaluate
Administer
Collect & Prepare (Bedside)

Product

Process
Recruit
Screen Donor Pre-transfusion testing Issue

Infectious Disease Test Medical


Decission to transfuse Monitor & Evaluate
Administer
Collect & Prepare (Bedside)

Blood Safety

Transfusion Safety
An adverse transfusion reaction
is “an undesirable response or effect” in a
patient temporarily associated with the
administration of blood or blood
component.

NHSN manual: biovigilance component protocol hemovigilance module, June 2011.


Guidelines and procedures for monitoring hemovigilance. http://www.cdc.gov/nhsn/bio.html.
Transfusion Reactions and
Incidents

?
The risks of blood transfusion :

• Immune / serologic reaction


• Blood transmitted infections
• TRALI
• TACO
• GvHD
• Mistransfusion
REPORTED TRANSFUSION REACTIONS

6 3 3
28 1% 63
2% 1% 19%
8%

Febrile
Chill
55
16% Urtika
Dispnoe
Palpitation
Hypotension
181 Others
53%
Reaksi Transfusi vs Komponen Darah

Reaksi Komponen
Transfusi darah
Komponen Darah
Untuk Transfusi
Red Blood Cells
Platelets
Fresh Frozen Plasma (FFP)
Cryoprecipitated Anti-hemophilic
Factor
Granulocytes
A B C
• Berlakukan
Apa jenis SOP Cari
reaksinya • Pasien & faktor
? Komponen
darah kausa

D Database

11
ALERTING SYSTEM

12
http://haemovigilanceindo.com

• National
haemovigilance system
is not yet formally held
in Indonesia,
• There is a start of
website available.
Simpulan

• Reaksi transfusi dapat terjadi oleh karena


faktor pasien maupun komponen darah.
• Konsep A-B-C-D dapat menjadi salah satu
pedoman dalam tahapan mitigasi reaksi
transfusi.
THANK YOU

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