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TABLE OF CONTENTS
Halaman

TABLE OF CONTENTS ................................................................................. i

CHAPTER 1 INTRODUCTION ..................................................................... 1

CHAPTER 2 LITERATUR REVIEW ........................................................... 3
2.1 HIV ................................................................................................... 3
2.1.1 Definition ............................................................................... 3
2.1.2 Etiology ................................................................................... 3
2.1.3 Pathogenesis ............................................................................. 3
2.1.3.1 HIV life cycle and host immune responses ............... 3
2.1.3.2 Immune dysfunction.................................................. 4
2.1.3.3 Immune activation ..................................................... 4
2.1.4 Mother-to-child Transmission (MTCT) ................................... 5
2.1.5 Factors influencing MTCT of HIV .......................................... 6
2.1.5.1 Viral factors ............................................................... 6
2.1.5.2 Host Factors of MTCT .............................................. 7
2.1.6 WHO clinical staging of HIV .................................................. 8
2.1.7 Diagnosis HIV ......................................................................... 10
2.1.8 Antiretroviral Therapy ............................................................ 13
2.2 Marasmus ......................................................................................... 15
2.2.1 Introduction ............................................................................. 15
2.2.2 Factors and Causes of Marasmus ............................................ 15
2.2.3 Clinical Feature ....................................................................... 16
2.2.4 Treatment ................................................................................ 16
2.2.5 Clinical Management .......................................................... 17
2.2.6 Complication ....................................................................... 17
2.2.7 Prognosis ............................................................................. 17
2.3 Tuberculosis ...................................................................................... 18
2.3.1 Clinical Features of Childhood TB ..................................... 18
2.3.2 Diagnosis .............................................................................. 19
2.3.3 Therapy ................................................................................ 20
2.3.4 Management of HIV-Associated TB Infection in Children . 21
CHAPTER 3 CASE REPORT ......................................................................... 24
3.1 Objective .......................................................................................... 24
3.2 Case ................................................................................................... 24

CHAPTER 4 DISCUSSION ............................................................................ 45

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CHAPTER 5 CONCLUSION ......................................................................... 48

REFERENCES ................................................................................................. 49