TECHNICAL

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C L I C K H E R E

M A I N M E N U H E L P
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Technical Manual, 16th edition

Technical Manual, 15th edition

Technical Manual, 14th edition

Technical Manual, 13th edition

Technical Manual, 12th edition

Standards, 1st-25th editions

Tutorial

About the AABB

M A I N M E N U H E L P
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Introduction/Index

Chapters

Methods/Appendices

Technical Manual, 16th ed. M A I N M E N U H E L P

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1. Quality Systems: Theory and Practice 9. Storage, Monitoring,

Pretransfusion Processing, and
2. Facilities, Work Environment,
Distribution of Blood Components
and Safety
10. Molecular Biology and
3. Regulatory Issues in Blood Banking
Immunology in Transfusion Medicine
4. Disaster Management
11. Blood Group Genetics
5. Allogeneic and Autologous Blood
12. ABO, H, and Lewis Blood Groups
Donor Selection
and Structurally Related Antigens
6. Whole Blood Collection and
13. The Rh System
Component Processing
14. Other Blood Groups
7. Blood Component Collection
by Apheresis 15. Pretransfusion Testing
8. Infectious Disease Screening 16. Identification of Antibodies to Red
Cell Antigens

Chapters 17 - 32

Chapters, 16th ed. M A I N M E N U H E L P

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17. The Positive Direct Antiglobulin 25. Transfusion Support for

Test and Immune-Mediated Hematopoietic Transplant Recipients
Hemolysis
26. Therapeutic Apheresis
18. Platelet and Granulocyte Antigens
27. Noninfectious Complications of
and Antibodies
Blood Transfusion
19. The HLA System
28. Approaches to Blood Utilization
20. Hemotherapy Decisions and Auditing
Their Outcomes
29. Collecting and Processing Marrow
21. Administration of Blood Products for Transplantation
Components
30. Hematopoietic Progenitor Cells
22. Perinatal Issues in Transfusion Collected by Apheresis
Practice
31. Umbilical Cord Blood
23. Neonatal and Pediatric
32. Tissue and Organ Transplantation
Transfusion Practice
and the Hospital Tissue
24. Blood Management Chapters 1 - 16 Transplantation Service
Chapters, 16th ed. M A I N M E N U H E L P
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Methods Appendices
1. General Laboratory Methods APPENDIX 1
Normal Values in Adults
2. Red Cell Typing
APPENDIX 2
3. Antibody Detection, Identifica-
Selected Normal Values in Children
tion, and Compatibility Testing
APPENDIX 3
4. Investigation of a Positive DAT
Typical Normal Values in Tests of He-
5. Hemolytic Disease of the Fetus mostasis and Coagulation (Adults)
and Newborn
APPENDIX 4
6. Blood Collection, Component Coagulation Factor Values in Platelet
Preparation, and Storage Concentrates

7. Transplantation of Cells and Tissue APPENDIX 5

Approximate Normal Values for Red
8. Quality Control
Cell, Plasma, and Blood Volumes
Appendices 6 - 11

Methods/Appendices, 16th ed. M A I N M E N U H E L P

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APPENDIX 6 APPENDIX 9
Blood Group Antigens Assigned to Distribution of ABO/Rh Phenotypes by
Systems Race or Ethnicity
APPENDIX 7 APPENDIX 10
Examples of Gene, Antigen, and Directory of Organizations
Phenotype Symbols in Conventional
APPENDIX 11
and International Society of Blood
Resources for Safety Information
Transfusion Terminology

APPENDIX 8
Examples of Correct and Incorrect
Terminology

Appendices 1 - 5

Appendices, 16th ed. M A I N M E N U H E L P

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Introduction/Index

Chapters

Methods/Appendices

Technical Manual, 15th ed. M A I N M E N U H E L P

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1. Quality Systems 9. Molecular Biology in Transfusion

Medicine
2. Facilities and Safety
10. Blood Group Genetics
3. Blood Utilization Management
11. Immunology
4. Allogeneic Donor Selection
and Blood Collection 12. Red Cell Antigen-Antibody
Reactions and Their Detection
5. Autologous Blood Donation
and Transfusion 13. ABO, H, and Lewis Blood Groups
and Structurally Related Antigens
6. Apheresis
14. The Rh System
7. Blood Component Testing
and Labeling 15. Other Blood Groups
8. Collection, Preparation, Storage, 16. Platelet and Granulocyte Antigens
and Distribution of Components and Antibodies
from Whole Blood Donations

Chapters 17 - 28

Chapters, 15th ed. M A I N M E N U H E L P

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17. The HLA System 23. Perinatal Issues in Transfusion

Practice
18. Pretransfusion Testing
24. Neonatal and Pediatric
19. Initial Detection and
Transfusion Practice
Identification of Alloantibodies
to Red Cell Antigens 25. Cell Therapy and Cellular Product
Transplantation
20. The Positive Direct Antiglobulin
Test and Immune-Mediated Red 26. Tissue and Organ Transplantation
Cell Destruction
27. Noninfectious Complications of
21. Blood Transfusion Practice Blood Transfusion
22. Administration of Blood and 28. Transfusion-Transmitted Diseases
Components

Chapters 1 - 16

Chapters, 15th ed. M A I N M E N U H E L P

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Methods Introduction 5. Hemolytic Disease of the Fetus

and Newborn
1. General Laboratory Methods
6. Blood Collection, Storage, and
2. Red Cell Typing
Component Preparation
3. Antibody Detection, Antibody
7. Quality Control
Identification, and Serologic
Compatibility Testing Appendices
4. Investigation of a Positive Direct
Antiglobulin Test

Methods/Appendices, 15th ed. M A I N M E N U H E L P

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APPENDIX 1 APPENDIX 7
Normal Values in Adults Examples of Gene, Antigen, and
Phenotype Terms
APPENDIX 2
Selected Normal Values in Children APPENDIX 8
Examples of Correct and Incorrect
APPENDIX 3
Terminology
Typical Normal Values in Tests of
Hemostasis and Coagulation APPENDIX 9
Distribution of ABO/Rh Phenotypes
APPENDIX 4
by Race or Ethnicity
Coagulation Factor Values in
Platelet Concentrates APPENDIX 10
Suggested Quality Control
APPENDIX 5
Performance Intervals
Approximate Normal Values for Red
Cell, Plasma, and Blood Volumes APPENDIX 11
Directory of Organizations
APPENDIX 6
Blood Group Antigens Assigned to APPENDIX 12
Systems Resources for Safety Information
Appendices, 15th ed. M A I N M E N U H E L P
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Introduction/Index

Chapters

Methods/Appendices

Technical Manual, 14th ed. M A I N M E N U H E L P

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1. Quality Systems 9. Molecular Biology in Transfusion

Medicine
2. Facilities and Safety
10. Blood Group Genetics
3. Blood Utilization Management
11. Immunology
4. Donor Selection and Blood
Collection 12. Red Cell Antigen-Antibody
Reactions and Their Detection
5. Autologous Blood Donation
and Transfusion 13. ABO, H, and Lewis Blood
Groups and Structurally
6. Apheresis
Related Antigens
7. Blood Components Testing
14. The Rh System
and Labeling
15. Other Blood Groups
8. Preparation, Storage, and
Distribution of Components from 16. Platelets and Granulocyte
Whole Blood Donations Antigens and Antibodies

Chapters 17 - 28

Chapters, 14th ed. M A I N M E N U H E L P

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17. The HLA System 23. Prenatal Issues in Transfusion

Practice
18. Pretransfusion Testing
24. Neonatal and Pediatric
19. Initial Detection and Identification
Transfusion Practice
of Alloantibodies to Red Cell
Antigens 25. Hematopoietic Transplantation
20. The Positive Direct Antiglobulin 26. Tissue and Organ Transplantation
Test and Immune-Mediated Red
27. Noninfectious Complications
Cell Destruction
of Blood Transfusion
21. Blood Transfusion Practice
28. Transfusion-Transmitted Diseases
22. Administration of Blood and
Components

Chapters 1 - 16

Chapters, 14th ed. M A I N M E N U H E L P

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Methods Introduction 5. Hemolytic Disease of the Newborn

Methods
1. General Laboratory Methods
6. Blood Collection, Storage, and
2. Red Cell Typing Methods
Component Preparation Methods
3. Antibody Detection, Antibody
7. Processing Hematopoietic
Identification, and Serologic
Progenitor Cells Methods
Compatibility Testing Methods
8. Quality Control Methods
4. I nvestigation of a Positive
Direct Antiglobulin Test Appendices
Methods

Methods/Appendices, 14th ed. M A I N M E N U H E L P

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APPENDIX 1 APPENDIX 6
Normal Values in Adults Blood Group Antigens Assigned
to Systems
APPENDIX 2
Selected Normal Values in Children APPENDIX 7
Suggested Quality Control
APPENDIX 3
Performance Intervals
Typical Normal Values in Tests
of Hemostasis and Coagulation APPENDIX 8
(Adults) Directory of Organizations
APPENDIX 4 APPENDIX 9
Coagulation Factor Values in Platelet Resources for Safety Information
Concentrates
APPENDIX 10
APPENDIX 5 AABB-Accredited Immunohematology
Approximate Normal Values for Red Reference Laboratories
Cell, Plasma, and Blood Volumes
APPENDIX 11
AABB-Accredited Parentage Testing
Laboratories

Appendices, 14th ed. M A I N M E N U H E L P

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Introduction/Index

Chapters

Methods/Appendices

Technical Manual, 13th ed. M A I N M E N U H E L P

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1. Quality Systems 9. Molecular Biology in Transfusion

Medicine
2. Facilities and Safety
10. Blood Group Genetics
3. Blood Utilization Management
11. Immunology
4. Donor Selection and Blood
Collection 12. Red Cell Antigen-Antibody
Reactions and Their Detection
5. Autologous Blood Donation
and Transfusion 13. ABO, H, and Lewis Blood
Groups and Structurally
6. Apheresis
Related Antigens
7. Blood Components Testing
14. The Rh System
and Labeling
15. Other Blood Groups
8. Blood Component Preparation,
Storage, Shipping, and 16. Platelets and Granulocyte
Transportation Antigens and Antibodies

Chapters 17 - 28

Chapters, 13th ed. M A I N M E N U H E L P

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17. The HLA System 23. Perinatal Concerns in Transfusion

Practice
18. Pretransfusion Testing
24. Neonatal and Pediatric
19. Initial Detection and Identification
Transfusion Practice
of Alloantibodies to Red Cell
Antigens 25. Hematopoietic Transplantation
20. The Positive Direct Antiglobulin 26. Tissue Banking and Solid
Test and Immune-Mediated Red Organ Transplantation
Cell Destruction
27. Noninfectious Complications
21. Blood Transfusion Practice of Blood Transfusion
22. Administration of Blood and 28. Infectious Complications of
Components Blood Transfusion

Chapters 1 - 16

Chapters, 13th ed. M A I N M E N U H E L P

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Methods Introduction 5. Hemolytic Disease of the

Newborn Methods
1. General Laboratory Methods
6. Blood Collection, Storage, and
2. Red Cell Typing Methods
Component Preparation Methods
3. Antibody Detection, Antibody
7. Quality Control for Equipment
Identification, and Serologic
Methods
Compatibility Testing Methods
Appendices
4. I nvestigation of a Positive
Direct Antiglobulin Test
Methods

Methods/Appendices, 13th ed. M A I N M E N U H E L P

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Introduction/Index

Chapters

Methods/Appendices

Technical Manual, 12th ed. M A I N M E N U H E L P

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1. Quality Assurance 9. Blood Group Genetics

2. Safety 10. Immunology
3. Blood Utilization Management 11. Red Cell Antigen-Antibody
Reactions and Their Detection
4. Donor Selection and Blood
Collection 12. ABO, H, and Lewis Blood
Groups and Structurally
5. Autologous Blood Collection
Related Antigens
and Transfusion
13. The Rh System
6. Hemapheresis
14. Other Blood Groups
7. Blood and Components
15. The HLA System
8. Molecular Biology in
Transfusion Medicine 16. Pretransfusion Testing

Chapters 17 - 26

Chapters, 12th ed. M A I N M E N U H E L P

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17. Identification of Alloantibodies to 22. Neonatal and Pediatric

Red Cell Antigens Transfusion Practice
18. The Positive DAT and Immune- 23. Hematopoietic Stem and
Mediated Red Cell Destruction Progenitor Cells
19. Blood Transfusion Practice 24. Tissue Banking and Organ
Transplantation
20. Administration of Blood and
Components 25. Noninfectious Complications
of Blood Transfusion
21. Obstetric & Perinatal
Transfusion Practice 26. Infectious Complications of
Blood Transfusion

Chapters 1 - 16

Chapters, 12th ed. M A I N M E N U H E L P

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1. General Laboratory Methods 6. Immune Hemolysis,

Autoantibodies, and Drugs
2. Red Cell Typing
7. Hemolytic Disease of the Newborn
3. Antibody Detection and
Compatibility Testing 8. Testing Donor Blood
4. Use of Antibody Titration, 9. Blood Collection, Storage, and
Alloantibody Identification, and Component Preparation
the Rare Donor File
10. Quality Control
5. Elution
Appendices

Methods/Appendices, 12th ed. M A I N M E N U H E L P

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1st Edition (1958) 9th Edition (1978) 18th Edition (1997)

2nd Edition (1960) 10th Edition (1981) 19th Edition (1999)

3rd Edition (1962) 11th Edition (1984) 20th Edition (2000)

4th Edition (1963) 12th Edition (1987) 21st Edition (2002)

5th Edition (1970) 13th Edition (1989) 22nd Edition (2003)

6th Edition (1972) 14th Edition (1991) 23rd Edition (2005)

7th Edition (1974) 15th Edition (1993) 24th Edition (2006)

8th Edition (1976) 16th Edition (1994) 25th Edition (2008)

17th Edition (1996)

Standards M A I N M E N U H E L P
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Tutorial M A I N M E N U H E L P
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Established in 1947, AABB is an international, not-for-profit association dedicated to the

advancement of science and the practice of transfusion medicine and related biological therapies.
It is committed to improving health by developing and delivering standards, accreditation, and
educational programs and services that optimize patient and donor care and safety.
For more detailed information, visit AABB’s Web site at www.aabb.org.
Other related publications from AABB:
Technical Manual, 16th Edition (print) Blood Transfusion Therapy:
Edited by John D. Roback, MD; Martha Rae Combs, A Physician’s Handbook, 9th Edition
MT(ASCP)SBB; Brenda J. Grossman, MD; Edited by Karen King, MD, and
and Christopher D. Hillyer, MD Jerome L. Gottschall, MD

Transfusion Therapy: Clinical Principles Practical Guide to Transfusion Medicine, 2nd Edition
and Practice, 2nd Edition By Marian Petrides, MD; Gary Stack, MD, PhD;
Edited by Paul D. Mintz, MD Laura Cooling, MD, MS; and Lanne Y. Maes, MD

Transfusion Medicine Self-Assessment and Review Transfusion Medicine Interactive:

By Pam S. Helekar, MD; Douglas P. Blackall,MD; A Case Study Approach CD-ROM
Jeffrey L. Winters, MD; and Darrell J.Triulzi, MD By Marian Petrides, MD; Roby Rogers, MD;
and Nora Ratcliffe, MD

About the AABB M A I N M E N U H E L P

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