MAHARASHTRA UNIVERSITY OF HEALTH SCIENCES,

NASHIK
(For Academic Year 2009-10 batch)

Scheme of Practicals for Final M.D. (Ayurved)

Subject – Bhaishajya Kalpana

Duration: - 2 Years

I) Departmental Practicals :-
Student should prepare following Aushadhi Kalpanas / perform practicals, (Any 100
100 out of 125) under the supervision of Guide and record the same in
Practical Journal (Proforma of journal is attached herewith as Annexure A)
a) Swaras Kalpana - 02
b) Kalka Kalpana – 02
c) Kwath Kalpana – 02
d) Him Kalpana – 02
e) Phant Kalpana – 02
f) Kshir Paka Nirman – 02
g) Panak Nirman – 02
h) Mantha Nirman – 02
i) Shadangodak Nirman – 01
j) Tandulodak Nirman – 01
k) Ghan Nirman – 02
l) Khand Paka Nirman – 02
m) Awaleh Nirman – 03
n) Ghrit Nirman – 02
o) Tail Nirman – 02
p) Bhallatak Tail Patan – 01
q) Laksha Ras Nirman – 01
r) Pramathya Nirman – 01
s) Asav Niraman – 05
t) Arishta Nirman – 05
u) Sidhu Nirman – 01
v) Sura Nirman – 01
w) Waruni Nirman – 01
x) Shukta Nirman – 01
y) Prassana Nirman – 01
z) Jagal Nirman – 01
aa) Medak Nirman – 01
bb)Sura Bij Nirman – 01
cc) Maireyak Nirman – 01
dd)Chukra Nirman – 01
ee) Sandaki Nirman – 01
ff) Guggul Shodhan – 01
gg)Guggul Kalpa Nirman – 08
hh)Gutika Nirman – 10
ii) Churna Nirman – 05
jj) Lavan Nirman – 02
kk) Mashi Nirman – 02
ll) Lepa Nirman – 02
mm)Malhar Nirman – 02
nn)Upanah Nirman – 01
oo)Kshar Nirman – 03
pp) Kshar Sutra Nirman – 03
qq)Basti Dravya Nirman – 05
 rr) Netra Bindu Nirman – 02
ss) Anjan Nirman – 02
tt) Shodhana of Visha, Upvisha and Dravyas – 12
uu)Preparation of Ahar Kalpana – 10
II) Research Project : (other than Dissertation) 1
Student should work on a specific topic related to Bhaishajya Kalpana as
allotted by Guide as per instructions and format provided in the P.G. Log Book
III) Compilations : 8
Student should prepare Compilations on a specific topic related to Ayurvedic
and Modern advances in Pharmacy / Bhaishajya Kalpana as allotted by Guide
as per instructions provided in the P.G. Log Book
IV) Clinical Case Study : (Desirable) 15
Student should study 15 cases and record the case in prescribed format
(attached herewith as Annexure B) as per instructions provided in PG Log
Book.
V) Drug Testing and Drug Standardization L: 10
Student should perform any 10 practicals using available tests at department
from following list, but at least two should be performed from each group.
A) Experiments for chemical analysis
a) Determination of Foreign matter
b) Determination of Moisture %
c) Determination of Ash value, ash analysis
d) Chromatography
B) Oils & Fats testing
a) Specific gravity
b) Refractive index
c) Estimation of Iodine value
C) Tests for preparations like asavas, aristas, tablets etc
a) Determination of pH value
b) Determination of Alcohol content of Asavas and Arista
c) Determination of Sugar content of Asavas and Arista
d) Determination of Viscosity (Oswald’s viscometer)
e) Determination of Specific gravity
f) Determination of Disintigration time for tablets
g) Hardness test for tablets
h) Friability test for tablets
VI) Academic Visits 8
The brief report of each visit should be written by student in a journal (Duly
signed by Guide and HOD)
a) Visit to one Local Ayurvedic Pharmacy (GMP Approved)
b) Visit to one State Ayurvedic Pharmacy (GMP Approved)
c) Visit to one out of State Ayurvedic Pharmacy (GMP Approved)
d) Visit to three R&D Centre of Modern Pharmacy (MNC) such as Glaxo,
Pfizer, FDA Laboratory etc.
e) Visit to Vipashana Centre and Pagoda Gorai, Mumbai (Desirable)
f) Visit to Siddha College and Siddha Pharmacy in Tamilnadu (Desirable)
 Annexure ‘A’
PROFORMA
Practical Journal Proforma

Practical No: _______________ Date: _____________

Practical name: ______________________________________________Time: _____________
Reference: ____________________________________________________________________
______________________________________________________________________________
______________________________________________________________________________
______________________________________________________________________________
______________________________________________________________________________
Equipments: __________________________________________________________________
______________________________________________________________________________
______________________________________________________________________________
Required Drugs:
No Drug Name Quantity Cost No Drug Name Quantity Cost
1 6
2 7
3 8
4 9
5 10

Method: _______________________________________________________________________
______________________________________________________________________________
______________________________________________________________________________
Procedure: ____________________________________________________________________
______________________________________________________________________________
______________________________________________________________________________
______________________________________________________________________________
______________________________________________________________________________
______________________________________________________________________________
______________________________________________________________________________
______________________________________________________________________________
______________________________________________________________________________
Observations: __________________________________________________________________
______________________________________________________________________________
______________________________________________________________________________
______________________________________________________________________________
______________________________________________________________________________

Precautions: ___________________________________________________________________
______________________________________________________________________________
______________________________________________________________________________
______________________________________________________________________________
(Diagram if applicable)

Final Processed drug: Weight Before _________________ After__________________

Loss _________________ Gain __________________
Change in weight due to _________________________________________________________
Examination of the Processed Kalpa:
1) Shabda : ____________________________________________________________
2) Sparsha : ____________________________________________________________
3) Rupa : ____________________________________________________________
4) Rasa : ____________________________________________________________
5) Gandha : ____________________________________________________________
Kalpa Siddhi Lakshanas: ________________________________________________________
______________________________________________________________________________
______________________________________________________________________________
______________________________________________________________________________
Standardization as per Modern Technology: ________________________________________
______________________________________________________________________________
______________________________________________________________________________
______________________________________________________________________________
Properties of the final Kalpa: - Quantity : ____________________________________
Observations : ____________________________________
Guna, Karma : _________________________________________________________________
Rogghnata : ___________________________________________________________________
______________________________________________________________________________
______________________________________________________________________________
Matra : ________________________________________________________________________
Anupan : ______________________________________________________________________
Special Applications : ___________________________________________________________
Abstract of Discussion (if any): ___________________________________________________
______________________________________________________________________________
______________________________________________________________________________
Conclusion : ___________________________________________________________________
______________________________________________________________________________

Date Date
Signature of Student Signature of Guide
Annexure ‘B’
 PROFORMA
Clinical Case Study

STUDY TITLE : Assessment of & confirmation of mode of action

SUBJECT NO : ______________________________________________________

SUBJECT NAME :

______________________________________________________

AGE :

______________________________________________________

SEX :

______________________________________________________

OCCUPATION : ______________________________________________________

ADDRESS : ______________________________________________________

___________________________________ TEL_______________

DATE OF FIRST VISIT : ______________________________________________________

INFORM CONSENT FORM :

______________________________________________________

PAST HISTORY/POORVA ROOPA :

________________________________________________

CHIEF COMPLAINTS/ROOPA:_____________________________________________________

INCLUSION CRITERIA :

______________________________________________________

EXCLUSION CRITERIA :

______________________________________________________

VISIT FIRST :

______________________________________________________

DATE OF VISIT : ______________________________________________________

 A) PHYSICAL EXAMINATION

SR. If Abnormal
Body system ND Normal Abnormality in brief
No NCS CS
1 Skin
Head, Eyes, Ears,
2
Nose, Throat
3 Respiratory
4 Cardiovascular
5 Gastrointestinal
6 Neurological
7 Lymphatic
8 Musculoskeletal
9 Urogenital
10 Other (Specify)
ND: Not Done, NCS: Not Clinically Significant, CS: Clinically Significant (If abnormal CS, enter in medical History)

B) SCREENING VISIT
VITAL SIGNS (in supine position after 3 min. rest)

Sr. If abnormal Abnormality

Parameter ND Value Normal
No. NCS CS in brief
1. Blood pressure(mmHg)
2. Heart rate(bpm)
Body temperature(ºF)
3. Oral
Axillary
4. Respiration Rate(/min)
ND: Not Done, NCS: Not Clinically Significant, CS: Clinically Significant (If abnormal CS, enter in medical History)

VYADHI PRAKRITI:____________________________________________________________
RUGNAPRAKRITI : ____________________________________________________________
DOSHA : ____________________________________________________________
DUSHYA : ____________________________________________________________
BALA : ____________________________________________________________
KAAL : ____________________________________________________________
VAYA : ____________________________________________________________
AGNI : ____________________________________________________________
PRAKRITI : ____________________________________________________________
SAAR : ____________________________________________________________
SATVA : ____________________________________________________________
SATMYA : ____________________________________________________________
AHARSHAKTI : ____________________________________________________________
VYAYAMSHAKTI : ____________________________________________________________
NIDAAN : ____________________________________________________________
AAHARJANYA : ____________________________________________________________
VIHARJAYNYA : ____________________________________________________________
VYASANJANYA : ____________________________________________________________
AUSHADHIJANYA: ____________________________________________________________
VYADHIJANYA : ____________________________________________________________
KAALJANYA : ____________________________________________________________
KULAJANYA : ____________________________________________________________
C) 12 LEAD ECG (in supine position after 5 min)
Date of examination
Sr. If abnormal Abnormality
Parameter Value Normal
No. NCS CS in brief
1. Qtc(msec)
2. QTcB(msec)
Overall interpretation
3.
of ECG
ND: Not Done, NCS: Not Clinically Significant, CS: Clinically Significant (If abnormal CS, enter in medical History)

D) CHEST X-RAY
Date of investigation:
If abnormal Abnormality
Examination ND Normal
NCS CS in brief
Chest X-ray
ND: Not Done, NCS: Not Clinically Significant, CS: Clinically Significant (If abnormal CS, enter in medical History)

E) HEMATOLOGY:
Date of sample collection:
Sr. If abnormal
Parameter ND Normal
No. NCS CS
1. WBC
2. RBC
3. Haemoglobin
4. MCV
6. MCH
7. MCHC
8. Platelate
9. WBC differential count
9.a Neutrophils
9.b Lymphocytes
9.c Monocytes
9.d Eosinophils
9.e Bosophils
ND: Not Done, NCS: Not Clinically Significant, CS: Clinically Significant (If abnormal CS, enter in medical History)
 F) URINE ANALYSIS:
Date of urine sample collection:
Sr. If abnormal
Parameter ND Normal
No. NCS CS
1. Protien
2. Glucose
3. Ketones
4. Blood
5. Bilirubin
6. Urine Microscopy
6.a Pus cells
6.b RBC
6.c Casts
ND: Not Done, NCS: Not Clinically Significant, CS: Clinically Significant (If abnormal CS, enter in medical History)

G) LIPID PROFILE

Sr. If abnormal
Parameter ND Normal
No. NCS CS
1. Total cholesterol
2. Triglycerides
3. HDL
4. LDL
5. VLDL
ND: Not Done, NCS: Not Clinically Significant, CS: Clinically Significant (If abnormal CS, enter in medical History)

DIAGNOSIS : ______________________________________________________

MEDICATION DETAILS : ______________________________________________________

SOURCES : ______________________________________________________

INGREDIENTS : ______________________________________________________

MANUFACTURING METHOD: _____________________________________________________

TEST DETAILS-Physical/Analytical : _______________________________________________

BATCH NO : ______________________________________________________
 H) MANUFACTURING DATE
Sr. Pharmaceutical
Ingredients Therapeutic value
No. value
1. Mercury
2. Sulphur
3. Copper
4. Iron
5. Aluminium
6. Zinc
7. Arsenic

DRUG/KALPA :______________________________________________________

ETIOPATHOGENESIS/HETU SAMPRAPTI :_________________________________________

BREAK UP OF ETIOPATHOGENESIS/Samprapti Vighatn : _____________________________

*ANCIENT POINT OF VIEW :_____________________________________________________

*MODERN POINT OF VIEW :_____________________________________________________

I) ADVERSE DRUG REACTION IF ANY

SR.N
Mercury Arsenic Lead Copper Zinc Iron Calcium
O
Same as of
Acute G.I arsenic except
Metallic Metallic G.I distur- Reduce
1. distur- diarrhea is Nausea
Taste Taste bance bone mass
bances replaced by
constipation
Throat Metallic Osteoporos
2. Nausea Dry throat Salivation Vomiting
constriction taste is
Burning
Metallic
sensation Burning in Diarr-
3. astringent Thirst Gullet
from mouth G.I tract hoea
taste
to stomach
Severe,
Radiating continous
Burning Constipa-
4. painover and Thirst Vomiting
in stomach tion
Abd. persisting
vomiting
Corrossion Iron
Colicky
of mouth , overload
5. Diarrhoea Nausea abdo- Diarrhoea
tongue , with organ
minal pain
faeces damage
Mucous
membrane Intense
6. Colicy pain Vomitting Collapse
appears thirst
grayish white
7. Nausea Cramps in Vomiting Diarrhoea Destruc-
legs tion
of mucus
membrane
 of mouth
Vomiting
with stringy
Bloody
8. mass of Oligouria Purging Collapse
purging
bloody white
mucous
Profuse Skin Liquid
Offensive
9. bloody eruption in brown
black faeces
purging later stage stool
Inky
Painful appear-
10. Cramps
tenesmus ance
of urine
Cardio-
Headache
11. respiratory Oligouria
drowsiness
arrest.
Severe
12. Paraylsis
headache
Encephalo
13. Dyspnoea
pathy
14. Sleeplessness Jaundice
Halluci- Muscle
15.
Nation cramp
16. Excitement Convulsion
17. Delerium Coma
Tremors of
18. eyes ,mouth
and fingers

WHO Scaling for ADR : ______________________________________________________

Temporal Relationship : ______________________________________________________

Concomittant Disease : ______________________________________________________

Concomittant Drug : ______________________________________________________

Causative Dechallenge : ______________________________________________________

Causative Rechallenge : ______________________________________________________

Comments : ______________________________________________________

Sign. of Student Sign. of Guide

Date :- Date :-