Beruflich Dokumente
Kultur Dokumente
1. Patient with carcinoma breast cT2N0M0 underwent mastectomy and sentinel lymph node biopsy.
SLNB was positive on frozen analysis. What is the next line of management
a. Completion ALND + adjuvant chemotherapy
b. Chemotherapy + RT to axilla
c. RT only
d. No further therapy
2.Which of the following is a SERM
a. Raloxifene
b. Exemestane
c. Letrozole
d. Anastrazole
3.Which of the following is a nonsteroidal aromatase inhibitor except?
a. Aminoglutethamide
b. Anastrazole
c. Letrozole
d. Exemestane
4.Glottic cancer with impaired vocal cord extending to either supraglottis or subglottis
a. T1
b T2
c. T3
d. T4
5.Sixty yr old man with locally advanced glottic cancer working at Radio station, treatment of choice is
a. Surgery
b. Radical RT
c. Chemoradiation
d. Surgery + RT
6. A young female with breast cancer. Her mother and grandmother had breast cancers. Her sister had
ovarian cancer. Which gene is implicated?
a. 13
b. 17
c. 21
d. X chromosome
7.Patient with 2cm lung nodule , biopsy proven adenocarcinoma. CT shows hilar lymph node 1.5cm and
left pleural effusion. Pleural fluid cytology is positive for malignant cells. What is the stage?
a. T1N1M0
b. T1N2M0
c. T4N1M0
d. T1N1M1
8. Patient with 3cm lung nodule carcinoma lung with solitary brain metastasis , best managed by
a. Palliative treatment
b. Surgery for both
c. Surgery for primary and RT to brain
d. Palliative chemotherapy
9. 70yr old male with carcinoma lung post treatment , on follow up after 1 yr had pathological fracture of
right neck of femur. No other lesions. Treatment of choice is
a. Palliative treatment
b. Immobilisation followed by RT
c. Hemiarthroplasty followed by RT
d. Immobilisation followed by chemotherapy
10.Post resection partial maxillectomy is reconstructed with
a. Myofascial flap
b. Skin graft + prosthesis
c. Free flap
d. Osteomyocutaneous flap
11.BRAF mutation is seen in which carcinoma of thyroid
a. Papilaary
b. Follicular
c. Anaplastic
d. Medullary
12.Most specific marker for melanoma
a. HMB 45
b. S 100
c. Synaptophysin
d. Melanin
13.Blood supply of ureter is by all except
a. Ovarian / testicular artery
b. Renal artery
c. Inferior vesical artery
d. Superior vesical
14.Thoracic duct crosses from right to left side at which level
a. 4th thoracic vertebera
b. 5th thoracic vertebera
c. 6th thoracic vertebera
d. 7th thoracic vertebera
15.Clavipectoral fascia is pierced by all structures except
a. Lateral pectoral nerve
b. Thoraco acromial vessels
c. Cephalic vein
d. Intercostobrachial nerve
16.Secondary swallowing in barium meal is seen in
a. Achalasia cardia
b. Hiatus hernia
c. Laryngeal diverticulum
d. Pharyngeal pouch
17. Most common site of extra adrenal phaeochromocytoma
a. Para aortic region near diaphragm
b. Para aortic region near aortic bifurcation
c. Carotid body
d. Urinary bladder
18. Drug of choice for cancer induced anorexia
a. Cyproheptadine
b. Dexmethasone
c. Megasterol acetate
d. Diphenhydramine
19. Patient's chest xray showing air fluid level 2 weeks post pneumonectomy is
a. Bronchial blow out
b. Retained air & fluid during surgery
c. Stomach herniation
d. Colonic herniation
20. Multiple skin malignancies, hypopigmented patches , sun burns are seen in syndrome deficiency of
a. Branched chain amino acid
b. Aromatic amino acid
c. Sphingolipids
d. Glycoproteins
21. Radiation therapy is most effective in which phase of cell cycle
a. G2M
b. S
c. M
d. G0
22. All the factors increase the sensitivity of radiation except
a. Hypoxia
b. Concurrent chemotherapy
c.
d.
23. Testicular lymphoma in elderly , all are true except
a. Most common secondary testicular tumor
b. Most common bilateral tumor
c. Good prognosis
d.
24. Treament of extra gondal germ cell tumor
a. Chemotherapy
b. Radiation therapy
'c. Surgery
d. Chemoradiation
25. Twenty eight year old male with hematuria , flank pain , bilateral palpable mass with hypertension
and uremia. Diagnosed as
a. ADPKD
b. Bilateral Renal cell carcinoma
c. Bilateral solitary cyst of kidney
d.
26. TB kidney most characteristic feature is
a. Sterile pyuria
b. Frequency
c. Hematuria
d. Flank pain
27. Post Neoadjuvant chemotherapy stage III carcinoma ovary patient undergoes TAH + BSO + para
aortic & pelvic lymphadenectomy with no residual disease ; defined as
a. Primary cytoreduction
b. Interval surgery with optimal cytoreduction
c. Staging laparotomy with optimal cytoreduction
d. Second look laparotomy
28. Carcinoma cervix IIa post radiotherapy with bleeding per rectum, Hb 4gm/dl , sigmoidoscopy
showing diffuse radiation proctitis. Treatment is
a. Conservative
b. Rectal excision
c. Endoscopic electrocautery
d. Endorectal formalin therapy
29. A 45 yr old fit female with carcinoma cervix stage IIb , treament is
a. Chemoradiation
b. Radical radiotherapy
c. Surgery
d. Chemotherapy
30. Commonly available vaccine , use of which has reduced the incidence of which cancer
a. Carcinoma cervix
b. Hepatocellular carcinoma
c.
d.
31. Carcinoma prostate most common site of origin is
a. Peripheral zone
b. Central zone
c. Anterior lobe
d. Transitional zone
32. Most common lymph node involved in carcinoma prostate is
a. Obturator
b. Iliac
c. Periprostatic
d. Perivesical
33. Double lumen cuffed endotracheal tube used for single lung ventilation has
a. one cuff in trachea , other in left bronchus
b. one cuff in trachea , other in right bronchus
c. one cuff in right bronchus , other in left bronchus
d.
34. Which nerve is preserved in Radical neck dissection
a. Accessory nerve
b. Ansa cervicalis
c. Greater auricular nerve
d. Hypoglossal nerve
35. All are true except
a. In DTPA , Tc99m is given intravenously
b. DMSA is for functional imaging of kidney and DTPA for renal parenchyma imaging
c. Less than 20% excretion is precarious
d. DMSA is used for function of kidney as well as pelvicalyceal excretion
36. Drug causing least myelosuppression is
a. Bleomycin
b. Cisplatin
c. Gemcitabine
d. Paclitaxel
37. Drug active in GIST
a. Cyclophosphamide
b. Imanitib
c. Bevacizumab
d. Cetuximab
38. All the following are true of gastro oesophageal tumors except
a. Stewart type III is managed by transhiatal esophagectomy and anastomosis in neck
b. Squamous cell carcinoma is not included
c. Stewart type I is in distal esophagus
d. Neoadjuvant chemotherapy followed by surgery is the treatment of locally advanced tumors
39. Chamberlain procedure is
a. Mediastinoscopy & biopsy
b. Thoracotomy & biopsy
c. Anterolateral parasternal mediastinotomy & biopsy
d. Mediastinotomy & biopsy
40. Following post gastrectomy for carcinoma stomach , absorption of which is not affected
a. Calcium
b. Vit.K
c. Vit.B12
d. Iron
41. Carcinoma gall bladder most important prognostic factor
a. Pericholedochal lymph nodal involvement
b. Liver invasion
c. Perineural invasion
d. Grade
42. In a carcinoma gall bladder with periportal invasion , DJ flexure invasion, peripancreatic &
retroperitoneal lymph nodes and mass invading porta hepatis all can be done except
a. Radical cholecystectomy after staging laparotomy
b. Ultrasound / CT guided biopsy / FNAC from the mass
c. Biliary stenting
d. Neoadjuvant chemotherapy & reassess for surgery
43. A patient operated for carcinoma colon showed stage III on histopathology underwent 6 cycles of
adjuvant FOLFOX. He was asymptomatic and develops a 3cm lesion in right lobe of liver. Patient
refused surgical resection of liver lesion. Which of the following treatments has the most curative
potential ?
a. Intralesional ethanol injection
b. TACE
c. RFA
d. Chemotherapy with irinotecan and bevacizumab
44. A 30 yr old female with 10yr history of OCP usage and alcohol consumption. She has right upper
quadrant abdominal pain and palpable mass in right hypochondrium. Liver biopsy shows positive for
glycogen laden enlarged hepatocytes and lipids. Diagnosis is
a. Focal nodular hyperplasia
b. Hepatocellular carcinoma
c. Hepatic adenoma
d. Metastasis
45. Which of the following has maximum incidence of metastasis ?
a. Glucagonoma
b. Insulinoma
c. Gastrinoma
d. Carcinoid tumor
46. Carcinoma pancreas is not seen in
a. Lynch I syndrome
b. Familial breast and ovarian cancer
c. Adenosis polypi coli
d. Ataxia telangiectasia
47. Most common second malignancy after total colectomy for Adenosis polypi coli is
a. Periampullary carcinoma
b. Small bowel carcinoma
c.
d.
48. AIDS defining malignancy include all except
a. Carcinoma cervix
b. Acute myeloid leukemia
c. Primary CNS lymphomas
d. Kaposi sarcoma
49. In a case of carcinoma rectum, all of the following with respect to preoperative versus
postoperative radiation are true except
a. Improved sphincter preservation
b. Decreases local recurrence
c. Decreases toxicity of radiation therapy
d. No overall survival difference
50. ___ manoeuvre is used in upper gastrointestinal endoscopy to see the fundus of stomach
a. J
b. H
c. I
d. U
51. Masoka staging is for
a. Carcinoid
b. Thymoma
c. Carcinoma gall bladder
d. Carcinoma stomach
52. In a carcinoma colon patient , the risk of developing colon cancer when the odds ratio is 2.4 for high
fat diet and 0.5 for green leafy vegetables is
a. High fat diet increases risk of colon cancer 2.4 times and green leafy vegetables decrease the
risk by 95%
b.
c.
d.
53. Young patient has undergone above knee amputation for osteosarcoma of proximal tibia and
adjuvant chemotherapy. On follow up, he develops 3cm solitary lung nodule. Treament is
a. Neoadjuvant chemotherapy followed by surgery
b. Metastatectomy
c. Chemoradiation
d. Radiotherapy
54. Most common causes of death in a case of carcinoma base of tongue
a. Aspiration pneumonitis
b. Cachexia and malnutrition
c. Bleeding
d. Asphyxia
55. Least carcinogenic virus in immunosupressed host is
a. CMV
b. HHV 8
c. EBV
d. HPV
56. Which of the following is a RNA virus
a. HCV
b. HBV
c. EBV
d. HPV
57. All of the following about short bowel syndrome are true except
a. Excision of 70% of intestinal length or more results in short bowel syndrome
b. Retaining the iliocaecal valve is associated with poor outcome
c. Children tolerate better than adults
d.
58. Definition of smoking pack years is
a. no: packs / day X no: years of smoking
b. no: packs / month X no: years of smoking
c.
d.
59. Migratory thrombophlebitis is associated with all except
a. Carcinoma lung
b. Carcinoma pancreas
c. Carcinoma prostate
d. Gastrointestinal malignancy
60. Limiting factor in the resection of colorectal liver metastasis is
a. Metastases in both lobes
b. Residual liver volume after resection
c. Number of metastases
d.
61. The recent increase in oral cancer attributed to HPV infection occurs most commonly in
a. Nasopharynx
b. Larynx
c. Oropharynx
d. Tongue
62. Boundaries of Poirot's triangle to identify thoracic duct are all except
a. Arch of aorta
b. Descending aorta
c. Vertberal column
d. Left subclavian artery
63. In pancreatic cancer, most common oncogene
a. KRAS
b. BRAF
c. p53
d. EGFR
64. All are tumor suppressor genes except
a. bcl 2
b. p53
c. Rb
d. BRCA 1
65. First event in pancreatic cancer
a. Telomere shortening
b. Telomere reactivation
c. p53 activation
d.
66. Young male 28yrs old has a tumor in right lower costochondral junction invading the chest wall with
underlying pleural effusion. Biopsy reveals small round cell cell tumor. IHC positive for mic2(CD 99).
Treatment is
a. Surgery
b. Chemoradiation
c. Neoadjuvant chemotherapy followed by surgery , adjuvant chemotherapy and radiotherapy
d. Surgery followed by chemotherapy
67. Clinical features of choledochal cyst include all except
a. Palpable mass
b. Jaundice
c. Fever
d. Abdominal pain
68. Charles Huggins received Nobel prize for bilateral subcapsular orchidectomy as a treatment of which
disease?
a. Carcinoma prostate
b. Carcinoma penis
c. Carcinoma testis
d. Male breast cancer
69. All of the following about dysgerminoma are true except
a. Comprises of montypic cells
b. Choriocarcinoma/ Yolk sac tumor component in mixed GCT is more sensitive to radiation
therapy as compared to dysgerminoma
c.
d.
70. The sequence of events after disclosure of cancer
a. shock, anger, denial , acceptance
b. acceptance, denial , anger , shock
c. shock , denial , anger , acceptance
d. anger , denial , acceptance , shock
71. A cancer patient with 4cm lung mass in CT scan undergoes neoadjuvant chemotherapy. Following
which the mass size has reduced to 3 cm size and scan shows no disease elsewhere . What type of
response ?
a. Complete response
b. Partial response
c. Stable disease
d. No response
72. Which is the wrong match?
a. Ewing's sarcoma t(11,22)
b. Synvial sarcoma t(x,18)
c. CML t(9,22)
d. Gardener's syndrome p53 mutation
73. Staging after neoadjuvant chemotherapy is depicted by
a. rTNM
b. pTNM
c. yTNM
d. xTNM
74. Resistance to chemotherapeutic agents is due to
a.
b.
c.
d.
75. Nottingham's grading system is used for
a. DCIS
b. LCIS
c. IDC
d. Invasive carcinoma
76. All are true about cholesterosis of gall bladder except
a. Due to defective transport of cholesterol crystals
b. resistance to infection
c. deposition of cholesterol crystals in gall bladder wall
d. is a premalignant condition
77. Prophylactic lymp node dissection is done in
a. Carcinoma tongue
b. Carcinoma buccal mucosa
c. Carcinoma gingivo buccal sulcus
d. Carcinoma lip
78. Extrinsic muscles of tongue are all except
a. Styloglossus
b. Palatoglossus
c. Genioglossus
d. Glossopharyngeus
79. Most common anomaly of hepatic artery noted during liver resection is
a. Accessory right hepatic artery originating from superior mesenteric artery
b. Replaced right hepatic artery originating from superior mesenteric artery
c. Accessory left hepatic artery originating from middle colic artery
d. Replaced left hepatic artery originating from middle colic artery
80.