DRUG STUDY

GENERIC NAME: Atropine Sulfate

Brand name: Atropair , Atropisol,Isopto Atropine
Drug Classification: ANS agent; Anticholinergic

DOSAGE, ROUTE, SIDE EFFECTS and

FREQUENCY (prescribed and INDICATION MECHANISM OF ADVERSE REACTIONS
recommended) ACTION (by system)
indicated when excessive Acts by selectively blocking Side effects: Dizziness,
Systemic administration: 0.4–0.6 (or sometime normal) all muscarinic responses to Headache, palpitations,
mg PO, IM, IV, or subcutaneously. muscarinic effects are acetylcholine anxiety, restlessness, nausea
judged to be life threatening
Ophthalmic solution: For (ACh),whether excitatory or and vomiting
or are producing symptoms
refraction: Instill 1–2 drops into inhibitor; Selective
sever enough to call of
eye 1 hr before refracting. depression of CNS Adverse effects: angina,
temporary, reversible
For uveitis: Instill 1–2 drops into muscarinic blockade ventricular ectopy,
eye qid. ventricular fibrillation

NURSING RESPONSIBILITIES
CONTRAINDICATION/S (at least 10)
Hypersensitivity, Angle-closure
glaucoma, obstructive uropathy,
obstructive diseases of GI tract

Drug –drug interactions: The

following may react with AtSO4:
antiarrhythmic drugs (e.g.,
quinidine, procainamide),
antihistamines (e.g.,
diphenhydramine, meclizine),
antispasmodics (e.g.,
dicyclomine), certain drugs for
Parkinson's disease (e.g.,
anticholinergics such as
benztropine, trihexyphenidyl),
MAO inhibitors (isocarboxazid,
linezolid, methylene blue,
moclobemide, phenelzine,
procarbazine, rasagiline,
selegiline, tranylcypromine),
other eye medications, tricyclic
antidepressants (e.g.,
amitriptyline).

Patient’s Name / Room No.