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Serum The test for adrenal cortical hyperfunction that has the
sodium and potassium analyses are done. The results greatest diagnostic sensitivity is measurement of:
would reveal:
Urinary free cortisol
Normal sodium, low potassium levels
Plasma cortisol
Low sodium, low potassium levels
Urinary 17-hydroxycorticosteroids
Low sodium, high potassium levels
Plasma corticosterone
High sodium, low potassium levels Urinary free cortisol
Low sodium, high potassium levels As a screening test for Cushing's syndrome, the
Hyponatremia (low serum sodium level) may be found in physician wishes to see whether a patient exhibits
all of the following conditions EXCEPT: normal diurnal rhythm of his cortisol secretion. At what
time should the specimens be drawn for plasma cortisol
Addison's disease determination? (Assume a daytime work schedule for
Diarrhea the patient.)
Renal tubular disease
6 AM, noon
Conn's syndrome 8 AM, 2 PM
8 AM, 8 PM
Congestive heart failure
Conn's syndrome Noon, 6 PM
A low-salt diet, low blood pressure, and diuretics would
cause the following results: Noon, midnight
8 AM, 8 PM
Increased renin, increased aldosterone, hypernatremia, A patient is suspected of having Addison's disease. His
hypokalemia laboratory tests show low serum sodium and chloride,
elevated serum potassium, and elevated urine sodium
Increased renin, decreased aldosterone, hypernatremia, and chloride levels. The aldosterone cortisol levels are
hypokalemia decreased. To make a definitive diagnosis, the physician
orders an ACTH stimulation test, and the cortisol level is
Decreased renin, decreased aldosterone, hyponatremia, measured again. If the patient has Addison's disease,
hyperkalemia the cortisol level would ________. If the patient has
hypopituitarism, the levels would _______.
Decreased renin, increased aldosterone, hyponatremia,
hyperkalemia Increase; decrease
Increased renin, increased aldosterone, hypernatremia,
hypokalemia Decrease; increase
The FINAL metabolite of epinephrine that is measured in
urine is: Increase; remain the same
Within 3 hours of taking 50 mg of captopril, plasma All of the above may be measured in a 24-hour urine
aldosterone was low. All but one of the above may be measured in a 24-hour
urine
All of the above are characteristic of hypoaldosteronism. All of the above may be measured in a 24-hour urine
All of the above are characteristic of hypoaldosteronism. Cushing's syndrome is characterized by which of the
During a low dose (1 mg) dexamethasone suppres-sion following?
test, total cortisol levels measured in a patient at 8:35
am was 2.8 ug/dL. How is this interpreted? Excess secretion of pituitary ACTH
Aldosterone Progesterone
Human chorionic gonadotropin (HCG)
Cortisol Chronic fetal metabolic distress is demonstrated by: