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Course: Nutrition
1. Introduction
– Human nutrition
– Public health nutrition
– Nutrition and development
– Causes of malnutrition
– Malnutrition and infection
2. Nutritional requirements
– Energy
– Proteins
– Fat
– Carbohydrates
– Vitamins 2
– Minerals
Course content…
3. Nutritional assessment
– Methods of nutritional assessment
– The present nutrition situation
– Nutritional surveillance
3
Course content…
5
Course Organization
6
Examples of topics for Literature
Review and Presentation
• Breast feeding and cognitive development
• Breast feeding and Social
development/family attachment
• Developmental origins of diseases
• HIV/AIDS and infant feeding
• Biofuels and Nutrition security
• Climate change and food security
• Etc.
7
Unit one: Introduction -
Outline:
– Definitions
– Forms of Malnutrition
– Causes/Etiology of Malnutrition
8
Nutrition
10
The science of Nutrition:
• Areas of Study
– Food production
– Diet composition (including non-nutritive
substances)
– Food intake, appetite, food preferences
– Digestion and absorption of nutrients
– Intermediary metabolism, nutritional
biochemistry
11
The Science of Nutrition:
Areas of Study
• Dietetics
– Science/ art of applying the principles of
nutrition in feeding
– Older subject, practiced by Hippocrates 460-
360 BC.
13
Public Health Nutrition
14
Malnutrition
15
Forms of Malnutrition
• Under nutrition
– Pathological state resulting from the consumption of
an inadequate quality/ quantity over an extended
period of time
• Over-nutrition
– Pathological state resulting from the consumption of
an excess quantity of food, and hence an energy
excess, over an extended period of time
16
The Scale of the Problem
17
Global Distribution of Malnutrition
18
Prevalence of chronic undernutrition in
developing regions (1969-1992)
19
Estimated prevalence and number of underweight
children 0−5 years old 1990−2005
20
Trends of malnutrition in Sub-Saharan
Africa (1983-2001)
21
Population at risk of and affected by micronutrient
malnutrition (millions) - 1992
22
23
24
What Is a Healthy Diet?
28
29
Malnutrition - Immediate causes
Immediate causes
31
Inadequate dietary intake/disease cycle
Appetite loss
Nutrient loss
Inadequate dietary intake
Malabsorption
Altered metabolism
32
Malnutrition - Immediate causes…
34
Malnutrition - Underlying causes
(HHFS)…
Household food security (HHFS)
35
Malnutrition - Underlying causes
(HHFS)…
36
Malnutrition - Underlying causes
(HHFS)…
37
Malnutrition - Underlying causes
(Services and sanitation)…
• Health services, safe water and
sanitation
– access to curative and preventive health
services that are affordable and of good
quality
39
Malnutrition - Underlying causes
(caring)…
45
Malnutrition - Underlying causes
(caring)…
• Care and support for mothers:
– As long as the unequal division of labour and
resources in families and communities continues to
favour men, and as long as girls and women face
discrimination in education and employment, the
caring practices vital to the nutritional well-being of
children will suffer
46
Malnutrition - Basic causes
47
Malnutrition - Basic causes…
– These include:
• the degree to which the rights of women and girls
are protected by law and custom;
• the political and economic system that determines
how income and assets are distributed; and
• the ideologies and policies that govern the social
sectors
48
Nutrition Intervention
50
Nutrition Interventions – short routes…
• Food supplementation
• Food stamps
51
Nutrition Interventions – short routes…
Behavior change
• Hygiene education
53
Nutrition Interventions – Long routes…
• Employment creation
54
Nutrition Interventions – Long routes…
Behavior change
58
Daily calorie requirements of
individuals
• Infants 1 - 3 years need 1,000 cal/day
• Children 5 years need 1,500 cal/day
• Children 5 – 8 years need 1,800 cal/day
• Children 10 – 12 years need 2,000 cal/day
• For adolescents and adults calorie
requirements depend on the degree of
physical activities 59
From 13 – 20 years of age
Adults
2,300-cal/day 2,700 cal/day
60
• Very heavy work up to 4,000 cal/day
• For pregnant woman, the daily figure must
be increased by 150 calories for the first
trimester and 350 for the second and third
trimester. For the nursing mother the daily
figure must be increased by 800 calorie.
61
Staple foods
62
Good nutrition enhances your quality of life and
helps you prevent disease. It provides you with the
calories and nutrients your body needs for maximum
energy and wellness.
NUTRITION: THE PROCESS BY WHICH THE BODY TAKES IN
AND USES FOOD.
NUTRIENTS: SUBSTANCES IN FOODS THAT YOUR BODY
NEEDS TO GROW, TO REPAIR, AND TO PROVIDE ENERGY.
CALORIES: UNITS OF HEAT THAT MEASURE THE ENERGY
USED BY THE BODY AND ENERGY SUPPLIED TO THE BODY
BY FOODS.
1. Hunger and Appetite:
Hunger: Natural need to eat and not starve.
Appetite: A desire to eat.
2. Emotions:
•Stress, Anger, Happy, Sad, Boredom, etc,
3. Environment:
•Family and Friends
4. Cultural and Ethnic Background:
•Race, Religion, Heritage
5. Convenience and Cost:
•Where you live, On the go lifestyle, Family income
6. Advertising:
•Health messages, Influence your looks
6 GROUPS OF NUTRIENTS:
•Carbohydrates
•Proteins
•Fats
•Vitamins
•Minerals
•Water
Carbohydrates: are the starches Simple carbohydrates: are
and sugars present in food. sugars. Examples include:
They are classified as either simple •glucose
or complex. •fructose
Complex carbohydrates are •lactose.
starches. Examples include:
•whole grains
•Body’s preferred source of
•seeds energy.
•legumes • Body converts all carbohydrates
to glucose, a simple sugar.
- Fiber is an indigestible complex
carbohydrate that helps move waste • Glucose is not used right away
through the digestive system. and it is stored as glycogen.
• Too many carbohydrates will
cause the body to store the excess
as fat.
carbohydrate
67
carbohydrate
68
carbohydrate
69
carbohydrate
70
CLASSIFICATION OF CARBOHYDRATES
Types of carbohydrates
• Monosaccharides:
• Glucose
• Fructose
• Mannose
• Galactose
72
Classification of carbohydrates
• Disaccharides:
Sucrose (a disaccharide present taste
sugar)
Lactose (a disaccharide present in milk)
Maltose (a disaccharide present in starch)
73
Classification of carbohydrates
cont,,,,
• Sugar alcohol: is found in nature and
also prepared commercially.
• Mannitol and dulcitol are alcohol derived
from mannose and galactose. Both have a
variety of uses in medicine and food
manufacture.
74
Classification of carbohydrates
cont,,,,
• Honey: is a mixture of glucose and fructose.
It is a balanced diet as it contains all the
nutrients in sufficient amount and proper ratio.
Honey has also medicinal effect. The bees first
cover the beehive with antibiotics to prevent the
growth and multiplications of microorganisms.
• If you keep honey for a long time, it will not be
spoiled because of antibiotics.
75
Classification of carbohydrates
cont,,,,
Glycogen:
is the animal equivalent of starch
present in the liver and muscle. In most
foods of animal origin it is a negligible
source of dietary carbohydrate.
• The glycogen in the liver is a reserve fuel
and it serves between meals and over
night. The breakdown of glycogen in the
liver is facilitated by the hormone
glucagons. 76
Classification of carbohydrates
cont,,,,
• Starch: is one form of carbohydrate
that is stored in granules in the roots
and seeds of plants.
77
How does fiber prevent different health
problems?
81
Carbohydrate digestion
a. Digestion of starch and disaccharides
-Chemical Starch, Lactose
salivary Amylase Dextrin, Lactase Sucrose
Mouth and
(Ptyalin) &
small
Pancreatic
intestine Sucrase
amylase Glucose
-Mechanical;- + Glucose
biting action of +
Galactose
the teeth Fructose
From the small
Maltoseintestine
Maltase
Glucose + Glucose
Absorbed by simple
diffusion
Production of
gases likes co2, Production of
methane and short chain fatty Increased faecal Biomass
hydrogen acids (SCFA) resulting in increased
sulphide Acetate peristalsis
Propionate
Abdiwahab H 83
Butyrate
Metabolism of Carbohydrates
Glucose –6-Phosphate
Glycolysis Fructose-6-phosphate
Fructose1, 6-diphosphate
Crebs Cycle
CO2+ Energy+H2O
84
• In Health and with normal diet, the available
carbohydrate is digested and absorbed completely
in the small intestine.
• If an excess of unabsorbed carbohydrate arise due
to a disorder of the absorption mechanisms or
occasionally to excessive intake, the osmotic
pressure (effects) leads to retention of fluids in the
lumen and as the result there will be watery
diarrhoea. This diarrhoea is known as osmotic
diarrhoea.
85
• The tissues use as fuel a mixture
of glucose and fatty acids. But the
brain normally uses only glucose
and requires around 80g daily.
86
• In starvation glucose may be provided by
gluconeogenesis from the amino acids in
tissues proteins, mainly from muscle
proteins, but fats cannot be converted into
glucose. With prolonged starvation the
brain adapts and can then utilize fatty
acids and ketone.
87
• The two hormones, which control the
metabolisms of carbohydrates,are insulin
and glucagons
Insulin is secreted by the beta cells of the
islets of Langerhans and the secretion is
stimulated by:
– Hyperglycemias
– Parasympathetic nervous activity
88
Function of insulin
89
• Glucagons is secreted by the alpha cells
of the islet of Langerhans and the
secretion is stimulated by
Hypoglycaemia
Sympathetic nervous activity
90
Function of glucagons
91
Proteins are nutrients that help build and maintain body cells and tissues.
NH2
Those amino acids that cannot be synthesized in the body and need
to be taken from food are essential (indispensable) amino
acids. 93
Cont..
• Absence Essential a.a.from the diet leads to poor growth
performance by a growing animal. Essential amino acids are
labelled by (**) sign in the following table .
94
WHY DO WE NEED PROTEIN TO SURVIVE ?
95
Classification of proteins
I. Based on chemical composition.
a)Simple protein - yield amino-acids upon
complete hydrolysis
E.g.: - albumin - in eggs, zein of corn
b.Compound/conjugated proteins
Protein + Non protein
E.g.: - Hgb (Protein + hem) - Blood
96
Cont..
II. Based on Nutritional Value:- This classification
depends on the essential amino acids content of the
protein.
a. Complete proteins: Contain all the essential amino
acids in the proportion that is required to support growth
and maintain tissues. E.g. Almost all animal proteins
except gelatine (lack two essential A.As.). They are
denoted as complete because they resemble body
protein (Egg & Milk).
b. Incomplete Proteins: This refers to proteins that do
not contain all essential amino acids in the proportion
that is required to maintain growth and tissue repair.
97
III. Based on Conformation of the Protein: This refers
to the three dimensional shape of the protein in its natural state.
Based on this proteins are classified as:
a.Globular proteins
-Tightly folded poly peptide chain - spherical or globular shape
-Mostly soluble in water
E.g.: - Enzymes, antibodies, and many hormones, Hgb
b. Fibrous proteins
-Polypeptide chains arranged in parallel manner along an axis
-Tough & in soluble in water
E.g.: - Collagen of tendons & bone matrix
- Keratin of hair, skin, nails and
- Elastin of blood vessels
98
IV. Based on their Chemical Structure
a. Primary structure : refers to the sequence of amino acids in
the polypeptide chain of proteins held by peptide bond.
Eg. Ala---gyc---Phenala---histd---tyr---trp
2. B-Pleated Sheath
99
c. Tertiary Structure: - This refers to the three dimensional arrangement of the protein
structure (whether it is folded upon itself giving rise to globular proteins or whether its
straight chain of poly peptides resulting in fibrous protein). This structure is maintained by the
sulfide bond.
d. Quaternary Structure:- This refers to the aggregation of individual poly peptide chains by
electrostatic bonding. Hemoglobin is a typical example of the quaternary structure of protein.
Hemoglobin A1 A2
B1 B2
100
Proteins
101
Proteins
102
Source of proteins
103
Source of proteins
104
Digestion and absorption of protein
105
Types of enzymes
106
Summary of protein digestion
107
The Amino Acid Pool
109
Danger of the Weaning period cont;;;;;
110
Danger of the Weaning period
cont;;;;;
• They also think that the baby in the womb is
jealous of the older sibling on the breast. It is
therefore considered urgent that the child should
be taken off the breast immediately
111
Danger of the Weaning period
cont;;;;;
• The mother may • The child has very
apply potions (bitter close relationship with
material) to the the mother, the
nipples so that when mother takes him/her
the child takes the back wherever and
breast the sharp bitter whenever she goes to
taste makes him/her fetch water or to bring
give up suckling.. firewood, the child
has also access to
breast milk on
demand.
112
Danger of the Weaning period
cont;;;;;
• The child sleeps on • This is a psychological
her back, but this blow for the child and
intimacy will be causes poor appetite
interrupted when the and as the result the
mother knows that child can develop
she is pregnant for protein energy
the subsequent child. malnutrition.
113
Protein energy malnutrition (PEM)
114
PEM:
117
PEM:
These include: Š
Seasonal food shortage Š
Unfavorable family condition, Š
Inadequate water supply and sanitary facilities,
Š Certain traditional attitudes during pregnancy, prenatal
period, breast-feeding and weaning periods, and
All infectious diseases, which generally reduce immunity.
118
PEM:
Other diseases may sometime play an important role
in precipitating the onset of kwashiorkor in already
malnourished child.
E.g. ƒ Gastrointestinal tract infection
ƒDiarrhea
Intestinal worms share the diet and cause other ill-
health and
poor appetite ƒ
Constipation ƒ
Childhood diseases such as measles, whooping
cough, etc, 119
Signs and symptoms of kwashiorkor
120
Skin changes
121
Hair changes
122
Physiological functions of the various
systems are markedly disturbed with:
• ƒ Diarrhea ƒ
• Electrolyte disturbance ƒ
• Circulatory insufficiency ƒ
• Metabolic imbalance ƒ
• Poor renal functions
• Hence the child with kwashiorkor should be
thought of as an emergency in need of referral to
the nearest health facility.
123
Nutritional Marasmus
125
Criteria for referral to the nearest health
facility
• Substantial weight def.<60%WAF or <70%
HFA
• Severe generalized edema and any of the
following:
– Anorexia
– Diarrhea and vomiting
– Dehydration
– Loss of consciousness and convulsion
126
Criteria for referral ……….
127
After discharge management of PEM:
128
Child status after discharge from
hospital
• ƒ Mental state has improved as shown by
smiling, response to stimuli, awareness, and
interest in the surroundings ƒ
• Appetite has returned and he/she is eating well ƒ
• Shows physical activity ƒ
• Temperature is normal ƒ
• No vomiting or diarrhea
• ƒ No edema ƒ
• Starting to gain weight.
129
Protein energy malnutrition
Possible causes
Check frequency of feeding, mechanics of feeding
Abnormal mother infant bonding
Objective
Atthe end of this lecture the students
should be able to describe the def.,
pathogenesis, clinical feature and
management of severe acute malnutrition
Outline
Introduction
Epidemiology
Cause
Classification
Pathogenesis
Clinicalfeature
Diagnosis
Complications
Principles of management
Prognosis and mortality
HUMAN NUTRITION
Nutrients are substances that are crucial
for human life, growth & well-being.
Macronutrients (carbohydrates, lipids,
proteins & water) are needed for
energy and
cell multiplication & repair.
development.
Assessment of Nutritional status
Clinical
Anthropometric
Dietary
Laboratory
Clinical Assessment
ADVANTAGES
Fast & Easy to perform
Inexpensive
Non-invasive
LIMITATIONS
Did not detect early cases
Trained staff needed
ANTHROPOMETRY
LIMITATIONS
Inter-observers’ errors in
measurement
Limited nutritional diagnosis
W F H
>90% ≤90%
% of reference standard
normal mild moderate
severe
Ht for age 95 90-95 85-90 85
(stunting)
Wt for age 90 80-90 70-80 70
(wasting)
Continued…
Biochemical
Serum proteins,
creatinine/hydroxyproline
Hematological
CBC, iron, vitamin levels
Microbiology
Parasites/infection
4. Biochemical Examination
Marsmus Kwash
Serum protein (alb)- Nl/mod ↓ ↓
Hgb/hct- ↓ ↓↓
Non ess to ess AA ratio- Nl ↑
Serum FFA- Nl ↑
Blood glu- Nl/low Nl/low
Total body protein- ↓ ↓↓
Transaminases- Nl/high High
DIETARY ASSESSMENT
malnutrition infection
Worsening of malnutrition
PEM in Sub-Saharan Africa
Poverty
End result –
reduced nutrient intake,
reduced nutrient absorption,
nutrient loss,
increased nutrient requirement
Environmental factors
Overcowded or unsanitary living
conditions
Agricultural patterns, drought, floods,
wars and forced migration lead to
cyclic, sudden or prolonged food
scarcities
Pathogenesis
1) Dietary theory –believed in 1960’s
Kwashiorkor-is primary protein malnutrition
accompanied by a relatively excess of
energy
Marasmus is under nutrition with lack of
predominantly energy
Marasmic kwashiorkor is a combination of
chronic energy deficiency and chronic or
acute protein deficit.
Early weaning and prolonged BF without
weaning
2) Maladaptation theory –
• kwashiorkor is essentially failure of
adaptation where the body utilized
proteins and conserve S/C fat
• marasmus is due to the elevated plasma
glucocorticoid concentration which are
associated with an increased rate of muscle
protein catabolism which provided
• energy for the body’s needs and
• released amino acids for the hepatic synthesis
of protein.
Continued…
Aflatoxin theory –
kwashiorkor results from aflatoxin
poisoning but
there is no difference in the
amount of aflatoxin in both
marasmus and kwashiorkor
Free radicals theory – Michael Golden
Imbalance between the
production of toxic free radicals
(superoxide,peroxidase) and their
safe disposal
The factors that increase free
radicals are
infections,
toxins,
sunlight,
trauma, and catalysts such as iron
Formation of free radicals is
decreased by the antioxidant function
of vitamin A, C, and E, by ceruplasmin
and transfferin
The toxic effect of free radicals would
be responsible for cell damage leading
to alteration seen in kwashiorkor, such
as edema, fatty liver, skin changes.
more comprehensive and include all
other theories
Summary
Low nutrient intake
Dysadapted Reductive
adaptation
marasmus
Small bowel
bacterial overgrowth Vitamin A, C, E
Infection Mn, Zn, Se
Aflatoxin Essential fatty acids
Fe Sulfur containing
amino acids
kwashiorkor
Birth / breast feeding
kwashiorkor Marasmic
kwashiorkor
Pathophysiology
Develops gradually allowing the body
to adapt for the low food intake,
enabling survival in a compensated manner.
The adaptive mechanisms:
1. functional limitation & ↓ interaction
with the physical & social environment.
↓Energy expenditure- Body fat mobilizn
↓ energy intake ↓ activity = wt loss
↑ muscle pro
↓ dietary amino acids ↓Protein synt in viscera
Catabolism=↑
& muscles
AA for visceral
Synt of alb, LP
2. hormonal changes in metabolism of
proteins, CHO, &fats.
- Marked recycling of aminoacids (AA),
- ↓ urea synth & excretion,
- t ½ of serum proteins ↑,
- rate of albumin synth ↓ , shift of
extracellular alb to intravascular space
(failure of this ↓ serum alb ↓ oncotic
pressure edema).
Cont…
Hormonal changes
Low plasma ↓insulin & somatomedin
Glu & AA ↑ epinephrine & GH
Infection, DHN
Reverse T3 ? ↓ T3 & T4
Cont…
membrane)
PSYCHOMOTOR CHANGES(Apathetic
GROWTH RETARDATION
USUALLY PRESENT
SIGNS
MOON FACE
HAIR CHANGES
SKIN DEPIGMENTATION
ANAEMIA
OCCASIONALLY PRESENT
SIGNS
HEPATOMEGALY
SIGNS OF INFECTIONS
Continued…
Kwashiorkor –
soft, pitting, painless edema, usually in
the feet and leg
Subcutaneous fat is preserved
Weight deficit is not as severe as
marasmus
Height may be normal or retarded
Continued…
The hair is dry, brittle, easily
pulled out without pain, pigment
changed to brown, red, or
even yellow white
‘Flag sign’ – due to alternating
period of poor and good protein
intake
Anorexic and diarrhea is common
Hepatomegaly
Protuberant abdomen and peristalsis is
slow
Muscle tone and strength is reduced
Marasmic kwashiorkor
Wellcome’s Classification:
Wt for Age edema no edema
(WFA)
W F H
>90% ≤90%
Solution Glu Na K Cl
g/dl mEq/L meq/L meq/L
WHO 2.0 90 20 80
Rehydralyt 2.5 75 20 65
e
Pedialyte 2.5 45 20 35
Infalyte 2.0 50 20 40
257
particular renal problem that makes the
children sensitive to sodium overload.
Dehydration:
Malaria
Measlesvaccine on the 4th week of treatment
Deworming – at the start of phase II
worm medicine is only given children who can walk
Albendazole 400mg PO STAT
mebendazole 100mg TWICE DAILY FOR 3 DAYS
Cont…
- add gentamicin, or
- change to amoxicillin/clavulinic acid.
4. Iron: given in phase II.
Phase I:
- pts with inadequate appetite and/or a
major medical cxn,
- formula used in this phase is F-75,
- promotes recovery of normal metabolic
fn & nutrition-ele balance,
- rapid wt gain is dangerous (F-75
ensures that).
Phase I
Diet– F75 (one sachet mixed
with 2 liters of water)
provides 75 kcal per 100 ml
8 feeds per day –larger volume
feeding can result in osmotic
diarrhea
Naso-gastric feeding is used if
the child takes less than 75% of the prescribed
diet
pneumonia with fast breathing
painful lesions of the mouth
cleft palate or other physical deformity
disturbance of consciousness
Diet – F100
Have unlimited intake
5 feeds of F100 are given
One porridge may be given
Always offer plenty of clean water while eating
Children must never be forced fed
Provide additional quantity of diet after feeding
Phase II: amount increased to ~180-
225ml/kg/day of F-100,
iron is added here
.
- criteria to move back to phase I:
Development of edema,
refeeding diarrhea with wt loss,
Wt loss of >5% of body wt at any visit
Wt loss for 2 consecutive weighing,
Static wt for 3 consecutive weighing.
Criteria for failure to respond
Primary failure to respond (phase I)
Failure to regain appetite (Day 4)
Failure to start to loss edema (Day 4)
Edema still present (Day 10)
Failure to enter phase II and gain 5g/kg/d (Day 10)
Secondary failure to respond
Failure to gain more than 5g/kg/d for three
consecutive days (during phase II)
Measure to take
Extensive history and examination or lab. Test
Look for hidden infection
Cont…
Discharge criteria:
Age • W/L (W/H) ≥85% on
6mo-18 more than one occasion,&
yr No edema for 10 days.
• target wt gain reached &
no edema for 10 days.
Prognosis
Upon treatment the acute signs of the disease
are corrected
Catch-up growth in height may take long or
might never be achieved
Mortality rate can be as high as 40%
Immediate cause of death are comp’n
particularly infections, hypoglycemia, and
dehydration
Mortality rates can be reduced to < 10% by
prevention and treatment of comp’n
• Fats are a type of lipid, a fatty
substance that do not dissolve in water.
• The building blocks of fats are called
fatty acids
• Fatty Acids are classified as two types
• Saturated:
– Animal fats and tropical oils
– High intake is associated with an
increased risk of heart disease
• Fatty acids that the body needs, but is
• Unsaturated:
unable to make are called essential fatty
– Vegetable fats acids
– Associated with a reduced risk of • Transport vitamins A, D, E, and K
heart disease
• Sources of linoleic acid- essential fatty acid
that is needed for growth and healthy skin
• High intake of saturated fats is linked to
increased cholesterol production
• Excess cholesterol can lead to an increased
risk of heart disease
Lipids
295
Lipids:
• ƒ Are the form of stored energy in animals
• Have high energy value 9 kcal/gm of fat ƒ
• Act as carriers for fat soluble vitamins ƒ
• Are palatable giving good taste and satiety ƒ
• Serve as insulator preventing heat loss from the
body ƒ
• Lubricate the gastrointestinal tract ƒ
• Protect the delicate organs such as Kidney,
Eyes, heart and the like.
296
Classification of lipids
297
• ƒHuman beings cannot synthesize the Poly
Unsaturated Fatty Acids (PUFA), hence they are
termed as essential FA. ƒ
• Saturated fatty acids tend to raise blood
cholesterol level. ƒ
• Polyunsaturated Fatty Acids lowers blood
cholesterol and large amounts of unsaturated
Fatty Acids are of vegetable origin and have
lower melting point.
298
Phospholipids, sterols and lipoproteins
299
Sterols
• These are precursors of vitamin D, which are
found both in plants and animals. Cholesterol in
animal’s tissues, egg yolk butter. Ergosterol in
plants
• Lipids are transported in the blood in the form of
lipoprotein (soluble fat protein complexes).
• They are 25-30% proteins and the remaining as
lipids
300
Lipoprotein
301
• Low-density lipoprotein (LDL) This is composed
mainly of cholesterol.
• LDL. Transports cholesterol from the liver to the
tissues. High serum level of LDL greatly increases
the risk of atherosclerosis ” is a disease in which
fatty deposits collect along the inside walls of
large or medium - sized arteries. These deposits
clog or narrow the passageway. If blood clots
become lodged in the narrowed vessels, the
blood flow to the heart or brain many be partially
or completely blocked, resulting in a heart attach
or stroke”. Diets that are high in saturated fatty
acids are associated with elevation in LDL
302
cholesterol.
Cholesterol
• Cholesterol is found • It is a major part of
only in animal brain and nerve
products. Plant foods, tissues. Cholesterol is
regardless of their fat necessary for normal
content, do not body functioning as
contain cholesterol. structural material in
Cholesterol is a fatlike the body cells, and in
lipid that normally the production of bile,
occurs in the blood vitamin D and a
and all cell number of hormones
membranes. including cortisone
and sex hormone. 303
• Hereditary, diet, exercise, and other conditions
affect blood cholesterol levels. Persons with high
blood cholesterol levels appear to be more likely
than those with normal levels to develop
atherosclerosis.
• No recommended dietary allowance has been
established for total fat or essential fatty acids;
however, the reduction in total fat is
recommended.
304
The essential fatty acids are: Š
• Linoleic acid Š
• Linolnic acid Š
•Arachidonic acid
305
The essential fatty acids are:
• Essential Fatty Acids are needed for the normal
functioning of all tissues
• Essential Fatty Acids form a part of the structure
of each cell membrane.
• Essential Fatty Acids help transport nutrients
and metabolites across the cell membrane
• Essential Fatty Acids are also involved in brain
development
• Essential Fatty Acids are needed for the
synthesis of prostaglandin
306
Linoleic acid:
307
Digestion of fats:
308
Digestion of fats:
309
Vitamins are compounds that help regulate many vital body
processes that include:
1. Digestion 2. Absorption 3. Metabolism 4. Circulation
• Š Vitamin D (Cholecalciferol)
• Š Vitamin E (Tocopherol) Š
• Vitamin K (Antihemorrhagic vitamin)
313
Function of vitamins:
314
Groups of vitamins:
315
Characteristics of water soluble
vitamins
• ƒ They are widely distributed in natural foods ƒ
• B 12 is found only in animal products ƒ
• Soluble in water and absorbed in the intestine ƒ
• Excess will be excreted, thus not toxic. ƒ
• Most functions of these vitamins are as co-
enzymes ƒ
• They are important for energy production ƒ
• They are heat labile
316
Characteristics of fat - soluble
vitamins
• ƒ Metabolize along with fats ƒ
• Resistance to heat ƒ
• Stored in the liver and adipose tissue ƒ
• Slow to develop deficiency syndrome ƒ
• Present only in certain foods, mostly in animal
products, oily foods, yellow and green vegetable
ƒ
• Excess can be toxic to the body.
317
Function of vitamin A
It controls the general state of the epithelial cells
and reduces the risk of infection. ƒ
It is required for the regeneration of two pigments,
visual purple in the rods of retina and visual violet
in the cones of the retina.
These two pigments are responsible for vision in
dim and bright light ƒ
It aids growth and development during childhood
ƒ
It helps to keep the cornea of the eye in healthy
condition.
318
Function of vitamin A
320
Vitamin A deficiency
324
The common symptoms of vitamin A
deficiency
• Š Night blindness: • Š Conjuctival xerosis:
The child cannot see The conjuctival
in the dark. He/she covering the white
has to go in to the surface of the
house early in the eyeballs become dry
evening. and rough instead of
being moist, smooth
and shining. The child
cannot open and
close his/her eyes
because it is painful.
325
The common symptoms of vitamin
A deficiency
• Bitot’s spots: A foamy or cheesy accumulation,
which forms in the inner quadrant of the cornea in
the eyes.
• The cornea the central transparent part of the eye
becomes cloudy.
• It reflects more advanced vitamin A deficiency,
but tends to be reversible with treatment.
326
The common symptoms of vitamin
A deficiency
• ŠCorneal ulceration: an ulcer on the cornea may
leave scar, which can affect vision. Š
• Keratomalacia: The eyeballs become opaque and
soft, jelly like substance; hereafter there will be a
rapid destruction of the eyeball and no hope of
recovery after the condition reached the stage of
keratomalacia.
327
• Diagnostic criteria for vitamin A deficiency at the
community level, WHO identifies a vitamin A
deficiency as a major public health problem if
prevalence of any one of the following in children
below six years of age exceeds the prescribed
levels.
328
Identifications of vitamin A deficiency at
the community level
Who cut - off level for identifying a
Vitamin A deficiency sign/symptoms public health problem
Conjuctival >0.01%
Xerosis/ulceration/keratomalacia
329
Prevention of vitamin A deficiency
332
Universal supplementation of vitamin a
capsules (short term strategy)
333
Fortification of foods
334
Fortification of foods
336
Vitamin B1 (Thiamine)
337
Vitamin B1 deficiency
338
Vitamin B1 (Thiamine) deficiency
2. Wet Beriberi
Symptoms: ƒ
•Gradual onset ƒ
•Loss of power of limbs ƒ
•Gradually develops edema and ascitis
339
Vitamin B1 (Thiamine) deficiency
3. Chronic Beriberi
•Symptoms: ƒ
•Paralysis of the lower extremities ƒ
•Cramping of the calf muscle ƒ
•Coldness of the feet ƒ
•Stabbing pain on walking ƒ
•Absence of knee and ankle jerks
340
Vitamin B2 (Riboflavin)
341
Deficiency of vitamin B2 is characterized by:
342
Vitamin B6 (Pyridoxine)
343
Deficiency of Vitamin B6
344
Vitamin B12 (Cobalamin)
345
Deficiency of vitamin B12:
346
Note:
347
Source of Niacin
348
Functions of Niacin
349
Deficiency of Niacin
350
Early signs and symptoms of Niacin
deficiency
• ƒFatigue,
• poor appetite, ƒ
• Weakness,
• mild digestive disturbance, ƒ
• Anxiety, irritability, ƒ
• Pellagra (a prolonged niacin deficiency), which is
characterized by the 4Ds which are:
Diarrhea
Dermatitis
Dementia
Death if the disorder is untreated. The skin is dry, scaly,
and cracked and the condition is aggravated by exposure 351
to heat or light.
Vitamin C (Ascorbic Acid)
352
Functions of vitamin C
353
Vitamin C
356
Vitamin D (cholecalciferol)
357
• Vitamin D is stored in the liver mainly; some is
stored in the brain, bones and skin as well.
• It undergoes changes in the liver, and in the
kidneys that convert it to active, hormone like
form.
358
Functions of vitamin D
359
Source of vitamin D
360
Deficiency of vitamin D
• It leads to rickets, which is characterized by
weakness and deformity of bones.
• Rickets generally occurs between the six months
to the second year of life, during the weaning
period.
361
On examination the skull bone of rachitic child, we will
find the following characteristics:
362
On examination the skull bone of rachitic child,
we will find the following characteristics:
• The chest is narrow and deformed
• The long limbs curve and may take the shape of a
bow and the sufferers are referred as bowlegs or it
may take the opposite shape i.e. the knees may
knock together and the sufferers may be described
as knock-knees.
• The vertebral column may curve, causing Kyphosis.
• Rickets in adults is known as osteomalacia, the
bones become soft and very painful.
• In women it causes difficult labor, as the pelvis
becomes contracted, thus narrowing the birth canal.
363
Vitamin k (Antihemorrhagic vitamin)
364
Deficiency of vitamin K
365
Minerals
• Minerals: are inorganic elements occurring in
nature. They are inorganic because they do not
originate in animal or plant life but rather from the
earth’s crust.
• Although minerals make up only a small portion of
body tissues, they are essential for growth and
normal functioning of the body.
• The body can make most of the things it needs
from energy foods and the amino acids in proteins
but it cannot make vitamins and minerals.
366
Benefits of minerals
• Minerals are essentials both as structural
components and in many vital processes,
• Some form hard tissues such as bones and teeth
• Some are in fluids and soft tissues.
• For normal muscular activity the ratio between
potassium and calcium in the extra cellular fluid is
important.
• Electrolytes, sodium and potassium are the most
important factors in the osmotic control of water
metabolism.
367
Benefits of minerals
• Some minerals may act as catalysts in the enzyme
system, or as integral parts of organic compounds
in the body such as:
�Iron in hemoglobin
�Iodine in thyroxin
�Cobalt in vitamin B12.
�Zinc in insulin and
�Sulfur in thiamine.
Plants, animals, bacteria, and other one celled
organisms all require proper concentration of
certain minerals to make life possible. 368
Benefits of minerals
• The principal minerals, which the body requires.
Calcium Chlorine Iron
369
Minerals cont,,,,
• Animals, in trace quantities, use minerals and these
are: Copper, Manganese, Cobalt, Zinc, and Fluorine.
• Other trace elements are present in animal tissues,
but their functions are uncertain and these are
Aluminum, Arsenic, Boron, Cadmium, and Silicon.
370
Minerals
371
Minerals
373
Causes of Iron Deficiency
374
Causes of anemia
375
Consequences of anemia
• Delayed psychomotor
development and • In adults, anemia with
cognitive performance in hemoglobin concentration
children and reduces work
adolescence.
• capacity, mental
• Neurological performance and
manifestation in children tolerance to infections.
and adolescents.
376
Consequences of anemia
379
Who needs more iron?
380
• Therefore, it is important that pregnant women
routinely receive iron supplements. In places
where anemia prevalence is high,
supplementation should continue into the
postpartum period, to enable them acquire
adequate stores of iron.
381
Iodine
383
Functions of Iodine
384
Iodine
385
Iodine
387
Why salt is iodized?
388
How long do we need to use iodized salt?
389
The benefits of iodized salt
390
The major consequences of iodine
deficiency
• Mental retardation • Decreased average
• Defects in the intelligence
development of • Loss of memory
nervous system • Inability to produce
• Goiter enough milk for
• Physical sluggishness offspring
• Reduced work • Lower birth weight
capacity • Growth retardation
• Impaired work
performance
391
The major consequences of iodine
deficiency
• � Dwarfism
• � Deaf-mutism
• � Cretinism
• � Reproductive failures (abortion, prematurity,
stillbirth)
• � Increased childhood morbidity and mortality
• � Economic stagnation and
• � Impotency.
392
Water helps to maintain many bodily
functions.
• Lubricates your joints and mucous
membranes.
- Enables you to swallow and digest foods.
- Absorb other nutrients, and eliminate
wastes.
- Perspiration helps maintain normal body
temperature.
• Water makes up around 65% of the body.
• It’s important to drink at least 8 cups of
water a day to maintain health.
Importance of water
398
Body water
399
Water in relation to body function.
400
Water in relation to body function
401
Water in relation to body function
402
Table. 7. Body water components in the reference man
403
Normal loss of water
404
Abnormally
405
Dehydration
407
Basal Metabolism
409
Factors affecting basal metabolism
• Sex:
Sex probably has little effect on metabolism.
Women have a lower metabolism than
men. Women usually have a less fat and
less
muscular development than men.
412
Factors affecting basal metabolism
• Climate:
Climate has little effect on BMR, which is
always measured in a room temperature.
413
Factors affecting basal metabolism
• Racial:
Differences in metabolism have been noted.
Eskimos have been reported to have a
BMR above accepted standards.
414
Factors affecting basal metabolism
• State of nutrition:
In starvation or under nutrition the BMR is
lower.
415
Factors affecting basal metabolism
• Diseases:
Diseases such as infection or fevers raise
the BMR in proportion to the elevation of
the body temperature.
The internal secretion of certain glands such
as the thyroid and the adrenal, affect
metabolism. Hyperthyroidism accelerates
metabolism by increasing production of
thyroxin.
416
Factors affecting basal metabolism
• Sleep:
Sleep varies depending on individuals,
some are restless and others are quiet.
417
Factors affecting basal metabolism
• Pregnancy:
After four months of gestation the BMR will
increase.
418
Are You Eating A Balanced Diet?
Product labeling advertise a food’s nutritious value. Some
common used terms are light, less, free, more, rich, rich in, lean, or excellent
source of. Many food products have open dates on their label. Examples are
expiration date, freshness date, pack date, and sell-by date.
1. Food Allergy - a condition in which the body’s immune
system reacts to substances in some foods.
•Allergies to peanuts, tree nuts, eggs, wheat, soy, fish,
and shellfish.
•A simple blood test can can indicate whether a person
is allergic to a specific food.
•These reactions may include rash, hives, or itchiness
of the skin; vomiting, diarrhea or abdominal pain; or
itchy eyes and sneezing.
2. Food Intolerance - a negative reaction to a food or part of
a food caused by a metabolic problem.
•The inability to digest parts of certain foods or food
components.
•May be associated with certain foods such as milk or
wheat, or even with some food additives.
•Common symptoms include nausea, vomiting,
diarrhea, and fever.
3. Food borne Illness – A term that means a person has food
poisoning.
423
Components of weight gain during pregnancy.
424
Causes for low weight gain during pregnancy
425
Causes for low weight gain during pregnancy
426
There are two main reasons for L.B.W:
427
Causes of premature delivery
428
Causes of retarded fetal growth
429
NB:
430
Proper care of children
• Appropriate hygiene and sanitation
• Safe food preparation and storage
• Successful breast feeding and adequate
weaning practice
• Psychosocial care such as attention,
affection and encouragement
• Equitable health services and a healthy
environment,
• Spacing of child birth.
431
Children at risk
434
435
Unit: Three
Assessment of nutritional status
• Nutritional assessment is the process of
estimating the nutritional position of an
individual or groups, at a given point in
time, by using proxy measurement of
nutritional adequacy.
• It provides an indication of the adequacy
of the balance between dietary intake and
metabolic requirement.
436
Uses of Nutritional Assessment
437
Diagnostic tool; (individual and group)
438
Monitoring tool (individuals and group)
439
Evaluation tool (individual or group).
440
Anthropometrics assessment
441
Anthropometrics assessment of growth
442
Indices derived from growth measurements;
• – Weight-for-height,
• – Height-for-age,
• – Body Mass Index (BMI) = Weight in Kg
divided by Height in metre square that is
Wt/(Ht)2
443
The Waterlow Classification
• Waterlow pointed out two different types of
deficit: a deficit in WEIGHT-FOR-HEIGHT
(wasting) and a deficit in HEIGHT-FOR-AGE
('stunting').
• 1. Waterlow has suggested classification
based on wasting (current malnutrition) or
stunting (chronic malnutrition)
• WFH = 80% of the Reference standard or
• –2.5D below the median
• HFA = 90% or – 2.5D below the median 444
Table: 8. Waterlow classification
Weight
Above Below
Height
• � Edema
• � Dyspigmentation of the hair
• � Angular Stomatits
• � Corneal lesions
• � Swelling (enlargement) of glands
447
Nutritional Surveillance
450
Objectives of nutritional surveillance
451
Potential users of Nutritional Surveillance
Information (N.S.I)
• � Ministry of health
• � Ministry of agriculture,
• � Government and nongovernmental
organizations.
452
Nutritional outcome indicators
50
Stunting
Underweight
25
0
0 12 24 36 48 60
Age (months)
Undernutrition in early childhood has serious
consequences;
More severe illness (diarrhea, pneumonia, etc.)
Strong exponential association between severity
of underweight and mortality,
Malnutrition
53%
Malaria 20%
Pneumonia
28%
22
School-age Children
Health-nutrition received attention recently,
Assumed to have passed critical stage, and
no longer vulnerable ?
Little data on health-nutrition (school children)
Many infections affecting preschool children
persist into the school years,
Malnutrition widespread in school children,
Adversely affect
school attendance,
performance, learning
Determinants of physical growth
Environmental + genetic factors
Poor food consumption pattern,
Illness,
Lack of sanitation,
Poor health and hygienic practices,
Potential for catch-up growth among stunted
children is limited after age two,
Particularly when children remain in poor environment,
Stunting at age two years associated with later
deficits in cognitive ability, regardless of catch-up,
School feeding (breakfast, lunch)
Improves school performance (hunger alleviation),
Malnourished children benefited most,
Cost-effective interventions
Mass application of antihelminthics,
Micronutrient supplementation (iron, iodine),
Treatment of injuries and routine health problems,
Blood pressure,
Noninsulindependent diabetes,
Coronary heart disease,
Cancer
Barker’s foetal origins of disease
hypethesis, …. Cont’d
• Iron Anemia
• Iodine Iodine Deficiency
Disorders (IDD)
• Vitamin A Xeropthalmia
• Zinc Multiple disorders
Anemia
• Blood loss
Anemia- Signs & Symptoms
• Tiredness and
fatigue
• Headache and
breathlessness
• Pallor: pale
conjunctivae,
palms, tongue, lips
and skin
Anemia- Assessment
• Blood can be tested for anaemia using different methods which
look at the colour of the blood, the number of blood cells, or use
a chemical which reacts with the haemoglobin.
– Hemoglogin (Hemocue)
– Hematocrit
• Defined by WHO as:
– Hb <11.0 g/dL – children
– Hb <12.0 g/dL – women
– Hb <12.0 g/dL - Men
Indicators of Iron Status
Lab
• Ferritin (FER)
• Fortification
• Iron supplements
Iodine Deficiency Disorders (IDD)
• Significant cause of preventable brain damage in children
• Health effects:
– Increased perinatal mortality
– Mental retardation
– Growth retardation
• Preventable by consumption of adequately iodized salt
Iodine Deficiency Affects
the Brain
Cretinism
Goiter
Reduced
intellectual
performance
Salt Iodine Measurement
Titration Lab
Rapid Kit
Qualitatively measures iodine content in salt
Highly sensitive but not specific
Field
Inexpensive
Vitamin A Deficiency (VAD)
1N Night blindness
2B Bitot’s spots
X3 Corneal xerosis
2B X3
X4 Corneal
ulcerations
-Keratomalacia
X5 Corneal scars
- permanent X4 X5
blindness
VAD- Risk Factors
• Low availability of
vitamin A-rich foods
• Lack of breastfeeding
• High rates of infection
(measles, diarrhoea)
• Malnutrition
VAD - Assessment
• Clinical assessment for night blindness
• Biochemical assessment
– Retinol
• Serum analyzed by HPLC
• Cutoff: < 0.7 µmol/L
• Reduced prevalence of
malaria in children in Papua
New Guinea
Zinc Deficiency
Hair loss
Skin lesions
Diarrhea
Poor growth
Acrodermatitis enteropathica
Death
Zinc Deficiency- Assessment
Deficiencies of:
• Vitamin C scurvy
• Niacin (vitamin B3) pellagra
• Thiamin (vitamin B1) beriberi
544
Methods of nutrition intervention
• � Food fortification
• � Food for work
• � Price subsidization
• � Supplementation
• � Family planning
• � Integration of nutrition with health
• � Price policy
545
Mechanisms of nutrition interventions
546
1) Availability of food at local or regional
level. Making the required foods more
available with the respect to place and
time.
547
2) Accessibility to food and availability of
foodstuff at the household level. Making the
required foods more accessible and
available to the households
548
3) Food utilization at household level.
Making better use of available foods. Food
processing such as fermentation, preparing
weaning food.
549
4) Distribution within the household.
• Intra household distribution of food
• Supplementation
• Education
550
5) Physiological utilization
•Health service activities and environmental
sanitation
•Primary health care
•Environmental health
551
Criteria used for successful interventions
554
There are seven action areas:
1. Promotion of Breastfeeding:
Key messages
• Timely initiation of breastfeeding (1 hour of birth)
• Exclusive breastfeeding until six months
• Breastfeed day and night at least 10 times
• Correct positioning & attachment
• Empty one breast before switching to the other
•Estimated decrease of child mortality is 13% if the
child is optimally breastfed
555
There are seven action areas:
556
There are seven action areas:
557
There are seven action areas:
558
There are seven action areas:
4. Women's nutrition:
Key messages:
•During pregnancy and lactation Increase
feeding
Iron/folic Acid Supplementations
Treatment and prevention of malaria
• De-worming during pregnancy
• Vitamin A Capsule after delivery 559
There are seven action areas:
6. Control of Anemia
Key messages:
• Supplementation of women and children
(IMCI)
• De-worming for pregnant women and
children (Twice/year)
• Malaria control
• Iron rich foods
• Fortifications 561
There are seven action areas:
562
There are six critical contact points in the lifecycle
564
There are six critical contact points
in the lifecycle
3. Postnatal and Family Planning:
•• EBF, Diet, Iron/Folic Acid
•• FP, STI prevention
•• Child's vaccination
565
There are six critical contact points
in the lifecycle
4. Immunizations:
•• Vaccination, Vitamin A
•• De-worming
•• Assess and treat infant's anemia
•• FP, STI, Referral
566
There are six critical contact points
in the lifecycle
5. Well child and GMP:
•• Monitor growth
•• Assess and counsel on feeding
•• Iodized salt
•• Check and complete vaccination
•• Vitamin A/de-worming
567
There are six critical contact points
in the lifecycle
6. Sick child:
•• Monitor Growth
•• Assess and treat per IMCI
•• Counsel on feeding
•• Assess and treat for anemia,
•• Check and complete vitamin A
•• Immunization/de-worming
568
Need to integrate ENA into other
health programme
1. a) Child survival EPI+
•b) Community IMCI
•c) Health facilities IMCI
2. a) Reproductive Health
•b) Women's Nutrition
•c) Lactational Amenorrhea Method
569
Need to integrate ENA into other
health programme
3. a) National immunization Days Polio and
Measles
4. a) Nutrition programme positive deviance
community GMP
5. a) Infectious Diseases, Control of Malaria,
Tuberculoses HIV/AIDS (PMTCT)
•How the Essential Nutrition Actions expand
coverage outside the health sector?
570
Need to integrate ENA into other sectors
571
Need to integrate ENA into other sectors
572
Need to integrate ENA into other sectors
573
NB:
• The most visible evidence of good
nutrition is a taller, stronger, healthier child
who learns more in school and become
productive, happy adults who participate in
society.
• Malnutrition dose not need to be severe to
pose a threat to survival.
574
NB:
• Worldwide, fewer than 20% of deaths
associated with childhood malnutrition
involve severe malnutrition; more
than 80% involve only mild or
moderate malnutrition.
575
Unit: Seven
Nutrition and Development
Why invest on
nutrition?
576
Nutrition and
Development
75
50
% stunted
25
0
1980 1990 1995 2000
60
40
%
20
40
20
0
1980 1990 2000
581
De Onis et al, 2000 - WHO Global Databank
%
G
10
20
30
40
50
60
0
ab
on
N
am
ib
ia
G
ha
na
Be
ni
n
K
en
C
am ya
er
M oo
n
au
rit
a
Ta n i a
nz
an
ia
E
rit
re
a
M
a
N li
Bu ige
rk ria
in
a
Fa
so
U
M g an
oz
am da
bi
qu
e
C
ha
R d
wa
nd
Et a
hi
op
i
Za a
M m
years, in selected east African countries
47
ad b
ag ia
as
ca
M r
Prevalence of stunting in children under five
al
aw
i
582
The Global conceptual framework for the causes of
malnutrition Reduced educability, lost
Functional
productivity, mortality, morbidity consequences
Immediate
Diet Health Causes
Majority (80%)
mild & moderate
UNICEF/94-1173 Pirozzi
Victims not aware
584
Child Malnutrition by Age Group
Percentage
75
50
Stunting
Underweight
25
0
0 12 24 36 48 60
Age (months)
585
Source:: EDHS 2005
What are the developmental
consequences quantitatively?
Profiles Model
UN Medium Population Projection
Mortality
Illness
Intelligence loss
Reduced productivity
588
Malnutrition
and
•
Child Survival
589
Child Mortality (2006-2015)
UNICEF/C-56-19/Murray-Lee
1.3 million child deaths 590
Breastfeeding Practices
100
75 Exclusive Complementary
Breastfeeding Feeding
49 50
% 50
UNICEF/93-COU-0173/Lemoyne
25
0
0-6 months 6-9 months
591
Infant Deaths due to Poor
Breastfeeding Practices
18%
592
Poor Breastfeeding Practices
50,000
infant deaths
UNICEF/93-COU-0173/Lemoyne
every year
593
Vitamin A Deficiency
Night blindness
Permanent blindness
594
Children with Vitamin A
Deficiency (VAD)
Permanent blindness
Xerophthalmia
Night blindness
Sub-clinical
Vitamin A deficiency
595
Low Birth Weight
13.5%
UNICEF/C-56-19/Murray-Lee
• 2006-2015: 0ver 600,000 infant
deaths
596
The Intergenerational
Cycle of Malnutrition
597
ACC/SCN, 1992
Key Actions
to Improve
Maternal Nutrition
598
Control of iodine deficiency
disorders
Ensure access to
and consumption of
UNICEF/90-058/Goodsmith
in every household
599
Control of vitamin A
deficiency
Distribute a
high-dose of
vitamin A within
UNICEF/C-56-19/Murray-Lee
six weeks after
delivery
600
Control of iron
deficiency anemia
Distribute
iron
supplements
during the
UNICEF/C-56-19/Murray-Lee
last six
months
601
Improve access to
family planning services
Delay
first pregnancy,
UNICEF/C-56-19/Murray-Lee
Increase birth
intervals
602
Increase food intake
lactation:
Pr e gnancy (at least 1
additional meal /
UNICEF/C-56-19/Murray-Lee
200kcal)
lactation (at least
2 additional 603
Decrease energy expenditure
in the mother
UNICEF/93-COU-0931/Ethiopia/Thomas
Access to labor saving devices 604
Care in emergencies
• Promote proper
caring practices
UNICEF/90-008/Lemoyne
during emergency
situations
including
HIV/AIDS
605
Integrate food security &
nutrition
•
Implement food
security activities
along with
LINKAGES Ethiopia
nutritional
interventions
606
Key Actions to Improve
Child Survival, Growth, and
Development (0-24 Months)
607
Breast Feeding
Promote
exclusive,
on-demand
breastfeeding
UNICEF/D0192-0060/Johnson
until 6 months
608
Complementary Feeding
Promote
appropriate
feeding
practices
from 6
to 24
months
609
Sick Child Feeding
Promote appropriate child feeding practices
during and after illness
610
Prevention of vitamin A
defciency
Distribute vitamin
A supplements
to children
6-59 months
611
Improve access to
preventive health
interventions
Immunization
Malaria
nets)
Safe water
Sanitation 612
Unit: Eight
Nutrition in emergencies
By
Saad Ahmed Abdiwali
Overview
• Of all the deaths that occur in major humanitarian
emergencies about 33 - 50% are associated with
malnutrition.
• in emergencies, the mortality rate is closely associated
with the severity of malnutrition.
• Malnutrition is already the highest risk factor for
illness and death in Africa.
• Four to five million children die in Africa each year
from malnutrition-related problems 620
Overview…
• These deaths are because of a
combination of factors, such as
• gross poverty
• gross under-development in the form
of
-high illiteracy,
-unclean water, and
-inadequate health facilities
621
Food security
means all people having access at all
times to the food needed for an active and
healthy life.
• Three things are required for overall food
security:
1. Adequate and stable food availability or a
consistent food supply in the affected area.
2. Food access, or the ability of the displaced
population to get to the food and be able to
afford it. 622
3. Bio-utilization
Food security…
Food insecurity, may exist at any level:
national, community, or household level.
• When a large number of people experience food
insecurity, a food emergency may occur.
• is not common during natural disasters that occur
suddenly
• Decreased rainfall ,,,,,,the early signs of a food
emergency……decline in food supply and an
increase in food prices.
623
Food security…
624
Food Security in Famine, Drought,
and Conflicts
themselves.
627
drought
• is any unusual, prolonged dry period that is severe
enough to reduce soil moisture and water supplies
below the minimum level necessary for sustaining
plant, animal, and human life.
Effects of drought
• Immediate — occurs due to overtaxing and drying
up of water supplies; this results in loss of crops,
livestock, and other animals and no water for
628
washing, bathing, and drinking
Drought…
631
Malnutrition
A condition in which health is impaired
due to a lack , imbalance, or excessive
intake of one or more nutrients.
For the sake of this presentation
• Malnutrition encompasses a range of
conditions, including acute malnutrition,
chronic malnutrition and micronutrient
deficiencies.
632
The impact of an emergency on nutrition
TRIGGERS
IMPACT ON POPULATION
Destruction of
Large-scale Breakdown of Loss of property Social
infrastructure
migration essential services and business disruption
(roads, markets
(health, water, (houses, land,
etc.)
sanitation etc.) animals, stock
etc.)
IMPACT ON HOUSEHOLDS
Reduced Residence in Lack of Loss of earnings Families
access to food overcrowded water, and access to split
settlements hygiene, health services
sanitation
IMPACT ON INDIVIDUALS
Malnutrition Disease
DEATH
633
637
Micronutrient Deficiency
Disorders
• lack of certain vitamins and minerals.
• lead to severe disability or even death.
• They often co-exist with acute malnutrition
• but emerge only during treatment of or
recovery from severe malnutrition
638
micronutrient deficiency disorders can
occur among displaced populations
Iron deficiency anemia:
Vitamin A deficiency
Zinc deficiency
Niacin deficiency, or pellagra
Thiamin (vitamin B1) deficiency
Vitamin C deficiency, or scurvy
Iodine deficiency
639
Nutritional Assessment in
emergencies
Definition: - Nutritional assessment is an
interpretation of anthropometric, biochemical
(laboratory), clinical and dietary survey data to
tell whether a person/ group of people is well
nourished or malnourished (Over nourished or
under nourished).
640
Anthropometric Assessments
Anthropometry
is the measurement of human growth and
body size to obtain information about an
individual’s health status in terms of his
intake of nutrients and past illness.
641
Anthropometric indicators of
Malnutrition
• Median WFH less than 80% indicates wasting
• Median HFA less than 90% indicates stunting
• Median WFA less than 80% median indicates underweight
• MUAC less than 12.5 cm indicates wasting
• BMI less than 17 indicates wasting in adults
• Malnutrition rate is the proportion of children aged 6 months to
5 years who are below –2 Z-scores or the median 80% of the
reference value.
642
Clinical Assessments
Anthropometric measurements do not
reveal all the signs of nutritional
deficiencies that affect mortality or
productivity.
a. Presence of nutritional oedema
b.Signs of vitamin deficiencies
c. Signs of mineral deficiencies
d.Signs of infectious diseases
643
Food Security Assessments
• Food Security indicators — markets,
food production, livestock, household
assets, employment, food gathering,
sufficiency of food and fuel, food
preparation and consumption,
breastfeeding, endemic micronutrient
deficiencies, etc.
644
Food Security Assessments...
• Public Health indicators — disease
patterns, access to health services and
feeding centres, nutrition education,
environmental risk factors, hygiene
measures, traditional medicinal practices,
etc.
645
Food Security Assessments...
• Social and Care Environment indicators
— especially with respect to vulnerable
populations (such as minority or separated
groups, pregnant women, breastfeeding
mothers), infant and young child feeding
practices, shelter and overcrowding, and
social support systems.
646
NUTRITIONAL SURVEILLANCE
647
The Early warning signs(EWS)
This includes data on :
– Crop assessments
– Epidemic diseases
– Nutritional status of vulnerable groups
– livestock conditions
– Impact of precipitation on crops and
livestock
– Market situation
– Magnitude of food shortages and measures
taken for mitigation.
648
Early warning signs(EWS)
Food crises
Production patterns
Market prices
Food stocks(food balance sheets)
Rainfall pattern
649
EWS cont…
Prevalence of malnutrition(PEM)
Wt/age, wt/ht,
BMI
Children’s growth
Infectious disease rates
Food intake relative to need
650
EWS cont…
Household food security
Employment levels
Market prices
Changes in real income and
purchasing power
Dietary energy supply
651
EWS cont…
Caring capacity
Maternal education
Literacy rates
Maternal employment
Public expenditure
Breast feeding(duration and percentage
652
EWS cont…
Malnutrition-infection complex
Incidence of diarrhea
EPI coverage
availability of clean water
Children’s wt for age
653
EWS cont…
Micronutrient deficiencies
Iron deficiency(rates of anemia
Vitamin A Deficiency (Night blindness) in
children
IDD(goiter, cretinism)
654
Source of data
1. Agricultural data food balance sheet
2. Socio-economic data(marketing, distribution
& storing
3. Food consumption pattern(Antropocultural )
4. ABCD studies
5. Vital and health statistics
655
The TRIPLe A’ CyCLe
• Surveillance should be followed by intervention
action in a cyclic manner
Assessment
of the nutrition
Situation of
A country or
A region
657
1. General Rations
• This is the distribution of food
commodities in sufficient quantities to
meet a family’s basic nutritional
requirements.
• The general ration usually consists of
– basic foods
– Complementary foods
658
GFD if 1>
660
Based on this nutrient composition, the
recommendation in Ethiopia is for the complete
ration/full basket:
661
2. Selective Feeding Programs
662
Selective Feeding Programs…
• Two types of selective FP
1. supplementary feeding and
2. therapeutic feeding.
• When the GR being provided is not
adequate, leading to an increase in
malnutrition
1.Targeted
2.Blanket
663
1. supplementary feeding
programme
1.1 Blanket SFP
For vulnerable group(U5,pregnant &
lactating mothers, elderly and those with
chronic disease.
1.2 Targeted SFP
For moderately malnourished group
664
SFP carried out
665
Nutrient Composition
666
Nutrient Composition…
667
Nutrient Composition…
668
Nutrient Composition…
669
670
Aggravating Factors
• poor household food availability and accessibility, GFR
below mean energy requirement
• CMR >1 per 10,000 per day
• epidemic of measles, whooping cough (pertussis), cholera,
shigella and other important communicable diseases
• high prevalence of respiratory or diarrhoeal disases
• high prevalence of HIV/AIDS
• outbreaks of diseases (malaria, etc.)
• low levels of measles vaccination and vitamin A
supplementation
• inadequate safe water supplies and sanitation
• inadequate shelter
• war and conflict, civil strife, migration and displacement 671
2. Therapeutic Feeding Programs
(TFP)
Provide a rehabilitative diet together with
medical Rx for diseases and complications
associated with the presence of SAM.
676
M&E FOOD AND NUTRITION
PROGRAMS
677
Indicators for which data should
be collected:
• Monthly attendance
• Proportion of exits – recovery rate, death
rate, defaulter rate, transfer rate
• Mean length of stay
• Average rate of weight gain
678
679
Evaluating Food and Nutrition
Programs
• Evaluating food and nutrition programs is
important because it measures their
effectiveness, identifies lessons for future
preparedness, mitigation, and assistance,
and promotes accountability.
11/21/15 683
Outline
What is food security?
Dimensions
11/21/15 684
What is food security?
11/21/15 685
food security
Food security exists when all people, at all
times, have access to sufficient, safe and
nutritious food to meet their dietary
needs and food preferences for an active
and healthy life (FAO)
11/21/15 686
Dimensions
11/21/15 687
Food sovereignty
is the right of peoples
to define their own food preferences and agriculture/food
production system;
11/21/15 688
Rosset (2003) argues that "Food sovereignty goes beyond the
concept of food security… [Food security] means that…
[everyone] must have the certainty of having enough to eat each
day[,] … but says nothing about where that food comes from or
how it is produced."
11/21/15 689
Food sovereignty” “right of peoples to define their
own food, agriculture, livestock and fisheries systems”,
in contrast to having food largely subject to
international market forces.
Source:
http://www.food first.org /pubs/ backgrdrs/ 1998/ s98v5n3.htm
)
11/21/15 691
Myth 1: Not Enough Food to Go Around
Reality
Enough food is available to provide at least
2.15 kg of food per person a day worldwide.
11/21/15 692
Myth 2: Nature's to Blame for Famine
Reality
It's easy to blame nature.
11/21/15 693
Myth 3: Too Many People
Reality
Although rapid population growth remains a
serious concern in many countries, nowhere does
population density explain hunger.
11/21/15 694
Myth 4: The Environment vs. More Food?
Reality
Efforts to feed the hungry are not causing the
environmental crisis.
Large corporations are mainly responsible for deforestation-
creating and profiting from developed-country consumer
demand for tropical hardwoods and exotic or out-of-season
food items.
Most pesticides used in the Third World are applied to
export crops, playing little role in feeding the hungry.
11/21/15 695
Myth 5: The Green Revolution is the Answer
Reality
production advances of the Green Revolution
are no myth
Great production increases were achieved
through the green revolution but hunger has
persisted
Increasing production alone cannot alleviate
hunger.
Fails to alter the distribution of economic
power that determines who can buy the
additional food.
11/21/15 696
Myth 6: We Need Large Farms
Reality
Small farmers typically achieve at least four to
five times greater output per acre than large-
scale farmers, in part because they work their
land more intensively and use integrated, and
often more sustainable, production systems.
Secure land tenure is needed, to give farmers
incentives to invest in land improvements, to
rotate crops, or to leave land fallow for the
sake of long-term soil fertility.
11/21/15 697
Myth 7 The Free Market Can End Hunger
Reality
The trade promotion formula has proven an
abject failure at alleviating hunger
Export crop production squeezes out basic
food production
11/21/15 698
Myth 9
Reality
Bombarded with images of poor people as
weak and hungry, we lose sight of the
obvious: for those with few resources, mere
survival requires tremendous effort
11/21/15 699
Myth 10 More U.S. Aid Will Help the Hungry
Reality
Foreign aid can only reinforce, not change, the
status quo.
Our aid is used to impose free trade and free
market policies, to promote exports at the
expense of food production
11/21/15 700
Myth 11 -We Benefit From Their Poverty
Reality
Low wages-both abroad and in inner cities at
home-may mean cheaper bananas, shirts,
computers and fast food for most Americans
Enforced poverty in the Third World
jeopardizes U.S. jobs, wages and working
conditions as corporations seek cheaper labor
abroad.
11/21/15 701
Myth 12: Curtail Freedom to End Hunger?
Reality
we see no correlation between hunger and
civil liberty ??
freedom taken as the right to unlimited
accumulation of wealth-producing property
and the right to use that property however
one sees fit-is in fundamental conflict with
ending hunger
11/21/15 702
Steps proved to be most effective at achieving
food security? seven pro-poor action areas
11/21/15 703
Unit: TEN
Infant and young child feeding
in emergencies situation
By
SAAD AHMED ABDIWALI
704
“Breast feeding is the most precious gift
a mother can give her infant. When there
is illness or malnutrition, it may be life
saving gift; when there is poverty, it may
be the only gift.” Ruth Lawrence, MD
705
PRACTICAL STEPS
on how to ensure appropriate infant and
young child feeding in emergencies.
1. Endorse or Develop Policies
• Each agency should, at central level, endorse or develop a
policy
• Policies should be widely disseminated and procedures at all
levels adapted accordingly.
2. Train Staff.
• ensure basic orientation for all relevant staff (at national and
international level) to support appropriate IYCF
• health and nutrition program staff and
• Specific expertise on breastfeeding counseling and support will
require technical training
706
Cont…
3. Co-ordinate Operations
an agency or group of agencies should responsible for:
• Policy co-ordination:
• Intersect oral co-ordination:
• Development of an action plan for the emergency operation
• Dissemination of the policy and action plan to operational
and non-operational agencies including donors
4. Assess and Monitor
determine the priorities for action and response
Obtain key information through RA & by informed observation
and discussion includes :
• Demographic profile: women, infants and young children,
pregnant women, un accompanied children
• predominant feeding practices
707
Cont…
5. Protect, Promote and Support Optimal IYCF with
Integrated Multi-Sectoral Interventions
• Ensure demographic breakdown at registration of children under five
with specific age categories:
0-<12months, 12-<24 months, 24-59 months to identify the size of
potential beneficiary groups
• Establish registration of new-borns within two weeks of delivery to
ensure timely access to additional household ration entitlement
6. Minimizes the Risks of Artificial Feeding as much as
possible.
• Procurement, management, distribution, targeting and use of breast
milk substitutes, other milks, bottles and teats should be strictly
controlled and comply with the International Code.
708
Introduction
• In emergencies, children under five are more
likely to become ill and die from malnutrition
and disease than anyone else.
• In general, the younger they are, the more
vulnerable they are.
• Inappropriate feeding increases their risks.
• Malnutrition during the early years of life has
a negative impact on cognitive, motor-skill,
physical, social and emotional development.
709
Risks of death highest for the youngest
Around the world, in non-emergency situations
• two thirds of under-five deaths occur during
the first 12 months of life.
• Whether this proportion changes in an
emergency depends in part on how infants
are fed.
• up to 10%of the malnourished children
admitted were under six months old, most
deaths were among younger children.
710
Increased illness (morbidity)
Lack of food, adequate water and shelter,
overcrowding,
inadequate sanitation,
separation of parents and children, and
trauma
are characteristic of emergencies.
Many of these increase child illness
711
Risks of death higher for
malnourished children
• Malnourished infants are much more likely to
die than are well-nourished infants.
• An underweight child who falls ill is much
more likely to die.
• Anemia and other micronutrient deficiencies
make children even more vulnerable.
• Low birth weight due to malnutrition of
pregnant mothers also is associated with
higher infant mortality
712
10.5 million deaths among children under 5
years old in all developing countries, 1999
• About 51% of deaths of children under five years
old are due to pneumonia, diarrhoea, measles
and malaria.
• over half of the deaths, about 54%, are
connected with underlying malnutrition.
• For that reason, a major part of both prevention
and treatment is to improve infant and young
child feeding as well as maternal nutrition.
713
714
Breast feeding protects infants in famine
• In the early 1980s, several years of drought
and crop failures triggered famine in the
Darfur region of Sudan during 1984-85.
• A survey in eight villages showed deaths
were closely related to age.
• Children of one to four years were six times
as likely to die as adults.
• But they were also three times as likely to die
as the infants under one year, a difference
that might be correlated with the almost
universal breastfeeding.
715
Recommendations
There is consensus on recommendations for
the best, the optimal infant feeding for
ordinary conditions. These are not changed
for emergencies.
Start breast feeding within one hour of birth.
Breast feed exclusively for six months.
From six months,add adequate
complementary foods.
Continue breastfeeding up to two years or
beyond.
716
Infant feeding
• Breastfeeding is the best way to feed an infant
• It the best quality food for infants, in emergencies or
non-emergencies
• BF has many Advantages to infant, mother & society
These include health, nutritional, immunologic,
developmental, psychological, social, economic, and
environmental benefits.
• Substitutes are inferior to breast milk
• The infant under six months benefits most from
exclusive breastfeeding.
717
Protection by BF is greatest for the youngest
infants even in non-emergency settings
• Not to breastfeed increases the risk of dying
by six times in infants less than two months
old, and
• even between 9 and 11 months the risk is
increased by 40%.
• Breastfeeding continues to provide the best
quality of food during the second year, and to
reduce the impact of illness.
718
Challenges to infant feeding in
emergencies
• In both ordinary life and emergencies, women
may sometimes have difficulties with
breastfeeding.
• These may have physical or social causes, or
simply be due to lack of confidence.
• These difficulties can in most cases be prevented
and overcome.
• If alternatives are unavoidable, it is important to
reduce the risks of using them as much as
possible.
719
Common concerns about BF
“Malnourished mothers cannot breastfeed.”
“The mother thinks she is not producing
enough milk to feed her baby.”
“Stress prevents mothers from producing
milk.”
“The mothers may have HIV and transmit it
through breastfeeding.”
720
Main tasks to do:
721
Alternatives to breast milk
and their problems
For use of alternatives to mother’s milk
wet-nursing
milk banks
infant formula
animal milk
powdered full cream milk
If artificial feeding is given, use of feeding
bottles should be avoided.Cup feeding is
possible from birth and a safer option.
722
For use of alternatives to mother’s milk
Mother has died or is unavoidably
absent.
Mother is very ill.
Mother is relactating.
Mother tests HIV positive and chooses
to use a breast milk substitute.
Mother rejects infant.
Infant dependent on artificial feeding
723
Problems in artificial feeding in emergency
• lack of water
• poor sanitation
• inadequate cooking utensils
• shortage of fuel
• daily survival activities take more time and
energy
• uncertain, unsustainable supplies of breast
milk substitutes
• lack of knowledge on preparation and use of
artificial feeding
724
Conditions to reduce dangers of
artificial feeding
Infant formula with directions in users’
language
Alternatively, ingredients and knowledge
for home-prepared formula
Supply of breast milk substitutes until at
least six months or until relactation
achieved.
Milk and other ingredients used within
expiry date
725
Additional requirements
• Easily cleaned cups, and soap for cleaning them
• A clean surface and safe storage for home
preparation
• Means of measuring water and milk powder (not
a feeding bottle)
• Adequate fuel and water
• Home visits to lessen difficulties preparing feeds
• Follow-up with extra health care and supportive
counseling
• Monitoring and correction of spillover
726
Some important points from International Code of
Marketing of Breast milk Substitutes
728
References:
1. Interagency working group on Infant and young child feeding in emergency.
Operational Guidance for emergency Relief staff and programe manager:
Nov.2001.
729