MultipleAlleles and Codominance

Human blood types are detennined by genes that iöllow the CODOMINANCEpattern of inheritance.
There are two dominant alleles (IAand 1B) and one recessive allele (i).

Blood Type Genotype Can donate blood to: Can receive blood from:
Phenot

o ii and O
universaldonor

AB IAIB O, AB and O
universalreceiver

PI A or JAi AB, A

B I BIB or 1Bi AB,B

I. Write the genotype for each person based on the description:

a. Homozygous for the "B" allele

b. Heterozygous for the "A" allele
c. Type O
d. Type "A" and had a type "O" parent
e. Type "AB"
f. Blood can be donated to anybody
g. Can only get blood from a type "O" donor

Sex-Linked Traits/lncomplete
Sex-Linked
The genes for hemophilia are located on the X chromosome. List the possible genotypes
and phenotypes of the children from a and a woman who is a
carrier. (HINT: You have to keep track of what sex the childrenare!)

00 Y
 Dihybrid Crosses
In humans there is a disease called Phenylketonuria(PKU)whichis caused by a recessive allele.
People with this allele have a defective enzyme and cannot break down the amino acid
phenylalanine. This disease can result in mental retardation or death. Let thcv
normalsnzvvme. Also in hutnans in a condition called galactose intolerance or galactosenua,
ISalso caused by a recessive allele. Let "G" represen! the normal allele for galactose
digestion. In both diseases, normal dominates over recessive. If two adults were heterozygous for
both traits €599}), what are the chances of having a child that is completely normal? Hasjust
PKU? Has just galactosemia? Has both diseases?
Use this space to predict the genotypes that can passed on by the parents:

Cze

ratio eæ:l
Genotypic -e

Phenotypic ratio
 Translation
For each of the following sequences, fill in either the DNA, the mRNA sequence, the rRNA
anticodons, or the amino acid sequences that have been left blank. If

DNA

.9

mRNAAUG ACU AGC UGG GGG UAU U AC UUU U AG

tRNA

S WD(D

DNA TAC CGC TCC GCC GTC GAC AAT ACC ACT

mRNA

tRNA cec Age •cc

Czuctne