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MALADAPTIVE COGNITIVE STRUCTURES Am J Psychiatry 135:5, May 1978
rial, the mechanisms and content of memory and re- Nonetheless, ifthe cognition did not interfere with her
call, and problem-solving attitudes and strategies are emotional well-being and general functioning. it would
all aspects of cognition (16). In short, cognition en- not be considered maladaptive. On the other hand, if
compasses the processes of knowing, as well as the the woman attached a negative value to her opinion of
products of knowing (16, 21). Many of the complex her appearance and considered appearance to be an
processes subsumed under the term ‘‘cognition’ ‘ are important aspect of her desirability as a person. she
still poorly understood. In the absence of a compre- would be likely to progress to inaccurate and dysfunc-
hensive theory of memory that would help to explain tional conclusions. such as ‘Nobody ‘ could love me be-
the consistencies in individual behavior over time, the cause I am ugly’ or ‘ ‘I might
‘ as well give up in life
existence of ‘‘cognitive structures’ ‘ or “schemata” since I don’t have much going for me.”
has been postulated (12. 14, 16, 22, 23).
Cognitive structures are relatively enduring charac-
teristics ofa person’s cognitive organization. They are THE COGNITIVE VIEW OF DEPRESSION
organized representations of prior experience; dif-
ferent aspects ofexperience are organized through dif- Beck (2. 24-27) has provided the most comprehen-
ferent schemata (16, 22). The concept of cognitive sive exposition ofthe cognitive view ofdepression. In
structures or schemata can be used to explain why contradistinction to current emphases that mood alter-
people react differently to similar or identical situa- ation is central in depressive syndromes (28), the cog-
tions, while a particular individual may show the same nitive approach focuses on self-castigation, exaggera-
type of response to apparently dissimilar events. tion of external problems, and hopelessness as the
A schema allows a person to screen, code, and as- most salient symptoms.
sess the full range of internal or external stimuli and to According to Beck (2. 26). the depressed person’s
decide on a subsequent course ofaction. When a per- thinking and preoccupation represent erroneous and
son is confronted with a particular situation, it is as- exaggerated ways of viewing oneself and events. The
sumed that a schema is activated that is relevant to depressed person is overly sensitive to obstacles to
that stimulus configuration (2. 14). The different sche- goal-directed activity. interprets trivial impediments
mata in the cognitive organization may vary in their as substantial. reads disparagement into innocuous
specificity and detail and the range of stimuli or pat- statements by others, and, at the same time, devalues
terns to which they apply. For example, a person may himself or herself. The characteristic depressive pre-
have a complex, multifaceted, and well-developed occupations are stereotypical and are evident in self-
cognitive schema to deal with problems in mathemat- report. fantasy, and dream content. Moreover, the
ics, but a simple, narrow schema to deal with sexual cognitions are frequently irrelevant and inappropriate
encounters. In our use of the term, schemata encom- to the reality of the situation and mirror a consistent
pass systems for classifying stimuli that range from negative bias against oneself (2, 24, 25).
simple perceptual configurations to complex stepwise Profuse negative cognitions inevitably lead to dys-
reasoning processes. phoria, reduced desire to provide for one’s pleasure or
The cognitive approach to behavior and psycho- welfare, passivity, and ultimately to giving up. The
pathology is different in many ways from previous psy- specific cognitive content is “chained” to a particular
chological perspectives. Previous models have used affect (25). Thus concern about an anticipated threat is
motivational or adaptational concepts that are so elabo- connected with feelings of anxiety; thoughts about
rate and remote from clinically observable phenomena being unloved and abandoned are associated with de-
as to preclude empirical validation (2). As we shall pressive feelings. Depressive cognitive content gener-
demonstrate, hypotheses derived from the cognitive ally relates to notions of loss or perceived subtractions
approach to depression are readily testable, and many from what Beck refers to as one’s “personal domain.”
of them have been supported by empirical evidence. The personal domain includes the individual, signifi-
Contrary to common belief among clinicians, the cant others, valued objects and attributes, and ideals,
cognitive approach to depression and psycho- principles, and goals held to be important (25). Thus if
pathology does not assume that a well-adjusted indi- professional accomplishment is a central and cher-
vidual is one who thinks logically and solves problems ished goal, a temporary setback may be magnified out
rationally (2, 13, 14). What is assumed is that to un- of proportion and seen as having devastating implica-
derstand and correct maladaptive behavior, the idio- tions about one’s abilities and one’s prospects for fu-
syncratic meaning people ascribe to their experiences ture achievement. As a consequence of such an over-
must be uncovered. Within this framework, we do not generalized negative interpretation, the depressed per-
try to alter or remove all idiosyncratic evaluations but son is likely to experience increased dysphoria,
only those that are dysfunctional or maladaptive. The dejection. and discouragement.
evaluations or idiosyncratic views that are pathogenic In the clinical depressions, the patient’s per-
of depression are generally associated with negative ceptions. interpretations, and evaluations are not con-
value judgments. For example, a woman’s belief that sensually validated, and the pervasive, negative bias
she is unattractive may not be consensually validated, against oneself remains relatively immune to conven-
and thus it may reflect an idiosyncratic cognition. tional corrective feedback. This negative view of one-
526
Am J Psychiatry /35:5, Ma 1978 MARIA KOVACS AND AARON T. BECK
self and the future also militates against the reality the most pointed and specific questioning. Lloyd and
testing of one’s ideas, active exploration of problem- Lishman (39. 40) reported empirical data that depres-
solving alternatives, and appropriate use of other sive recall is biased toward negatively toned material;
people as resources. the extent ofnegative recall is related to the severity of
Beck’s approach to depression and its derivative the depression and to depression as a diagnosis. The
treatment, cognitive therapy (2. 26). is targeted on se- characteristically biased recall was also documented
lected aspects of the patient’s thinking and behavior. by the work of Nelson and Craighead (41). who
In a recent review (29) we summarized the content and showed that depressed subjects tend to remember
process peculiarities ofdepressive cognitions and their more experimental punishment and less positive ex-
relationship to affect. perimental reinforcement than nondepressed subjects
do. Other studies (42,43) have indicated that de-
pressed subjects underestimate the amount of positive
DEPRESSIVE COGNITIONS: CONTENT AND experimental reinforcement they receive.
PROC ESS Our clinical observations of depressed patients also
disclose that they have a strong tendency to assign
The content of depressive cognitions is pre- negative global and personalized meanings to events.
dominantly negative in tone and self-referential in di- For example. one of our patients, who repeatedly
rection; the individual is preoccupied with self-deroga- called friends and sought advice when he was in dis-
tory and self-blaming thoughts. Moreover, the de- tress. wrote in his diary. ‘I am despicable
‘ for asking
pressed patient projects into the future his or her opinions. He believed
‘ ‘ that his multiple phone calls to
notions of real or imagined loss. He or she becomes friends reflected his inability to handle his own prob-
pessimistic and hopeless and believes that the current lems. Moreover, he was convinced that this alleged
discomfort is unending and unalterable. Beck (2) has weakness detracted from his ‘worth’ ‘ as a person and
referred to the thematic content of depressive cogni- actually made others think unfavorably of him.
tions as the ‘‘negative cognitive triad,’ ‘ a negative. de- The depressed patient is especially prone to dis-
meaning view of oneself, the world, and the future. A qualify prior positive experiences and to personalize
number of empirical investigations support the com- experiences of failure. The latter are often interpreted
mon clinical observation that depression is associated as indicative of his or her blameworthiness. For ex-
with negative, self-referential cognitive content (30- ample, a patient was not pleased when a short story
33). she had written was accepted for publication because
Much of our knowledge about ourselves and the she attributed the acceptance to sheer luck. However,
world is meaningful only when considered in a time di- she regarded a rejected article as proof of her in-
mension. In addition, most ofour actions implicitly re- competence and felt distraught. A similar phenomenon
flect future goal-orientation (13. 16, 17, 34). It has was reported by Stuart (38), who found that depres-
long been noted that a disturbance in time orientation, sive tendencies correlate with evaluative rather than
such as a constricted time perspective, is indicative of classificatory associations, i.e. . associating the word
psychopathology (13, 34). In the clinical interview the ‘ ‘apple’ with “sweet”
‘ (evaluation) rather than “fruit”
depressed patient’s highly constricted time per- (classification). Empirical work (44, 45) has docu-
spective is evident in statements that he or she has “no mented the fact that depressed subjects personalize
future” or “nothing to look forward to.” In other failure; they ascribe failure in an experimental task to
words, in depression the future loses its meaning as a lack of ability, while they do not attribute success to
portent for prospective solutions (35); in the patient’s internal factors.
eyes the future becomes a singular state of unending The depressed patient’s characteristic stereotypical
pain and despair rather than a multiplicity of experi- conclusions and assessments reflect a combination of
ences and opportunities. negative cognitive themes and certain systematic er-
A number of studies have documented the fact that rors of thinking (2, 26). A characteristic error in de-
distorted construction of temporal experience is in- pressive thinking is drawing conclusions in the ab-
deed one of the characteristics of depressive cogni- sence of or contrary to evidence. This process of arbi-
tions. Compared with both nondepressed “normal” trary inference is illustrated by the following
people and nondepressed psychiatric patients such as cognition: “John didn’t call tonight. . . . He probably
schizophrenic and manic individuals, depressed pa- doesn’t want to see me anymore.” When depressed
tients manifest specific distortions of temporal sche- patients are confronted with a negative event or attri-
mata (35-38). bute they typically magnify its importance; however,
Recall, an additional aspect of cognitive functioning, the implications of a pleasant event or positive attri-
is also characteristically skewed in depression. De- bute are minimized. For instance, a patient evaluated a
pressed individuals selectively recall material with slight increase in her dysphoria to mean that she was
negative content or implication at the expense of neu- “deteriorating.” while she viewed a well-done task as
tral or positively toned material. In the clinical inter- quite insignificant. In clinical work we typically find
view they usually paint the bleakest picture of their that the patient selectively abstracts isolated elements
background; positive material can be elicited only by of a situation that are most consistent with his or her
527
MALADAPTIVE COGNITIVE STRUCTURES Am J Psychiatry 135:5, May 1978
negative and pessimistic world view and ignores other premises can be described in terms ofcommon themes
salient cues. A depressed patient decided that her or leitmotifs. each depressed patient has a distinctly
boss’s failure to say hello was ominous; she complete- personal set of rules or formulas that he or she uses to
ly ignored the fact that he was under considerable integrate experiences. These formulas are generally
pressure and preoccupied. As Beck and Shaw (27) unarticulated. Nevertheless. their content can be in-
have noted, the depressed patient’s invariant method ferred vis-i-vis the patient’s goals, self-evaluations,
of information processing results in overgeneralization and the meanings he or she assigns to the raw data of
and the ignoring of fine discriminations. his or her experiences. In addition, the depressed pa-
Hammen and Krantz (30), Weintraub and associ- tient’s stereotypical and rigid notions and directives
ates (33). and Beck (2) have reported empirical data are often the surface’
‘ ‘ manifestations
‘ of an under-
that document the presence and preponderance of er- lying depressogenic premise.
roneous cognitive processes in depressed college stu- For example, depressed patients tend to make ex-
dents and depressed patients. The depressive tenden- cessive use of the directives should’ ‘ ‘ and “must.” ‘
pressed subjects’ hypersensitivity to experimentally people. the depressed patients’ directives are general-
manipulated failure, compared with the reactions of ly unreasonable. rigid. and unyielding; the goal, which
nondepressed subjects. Loeb and associates (46) and reflects the depressive premise, is usually unattain-
Hammen and Krantz (30) have documented the fact able. One of our patients was preoccupied with how
that such manipulations lead to increased dysphoria she ‘should’
‘ ‘ and ‘must’
‘ study ‘ every day, contact
and pessimism. decreased levels ofaspiration. and less her family regularly. be undemanding of others. and
positive predictions of one’s performance on sub- always present a neat, organized appearance. The pro-
sequent tasks. fuse, content-specific use of ‘should’ ‘ eventually ‘ re-
vealed her underlying premise: ‘I have to be perfect
‘ at
everything. ‘ ‘ Another patient repeatedly and stereo-
DEPRESSOGENIC PREMISES AND SCHEMATA typically concerned herself with themes that reflected
her dependence on other people; one of her basic
It is clear that a concept is needed to integrate the premises concerning herself was I need ‘ ‘the continu-
various cognitive distortions that characterize de- ous presence of others for survival. Depressed “ pa-
pressed thought. This integrative concept should also tients also frequently use premises such as ‘I should ‘
help explain why, given certain internal or external be able to endure any hardship with grace,’ ‘I should ‘ ‘
events, some people develop a clinical depression and always be generous, dignified, and courageous.’ “I ‘
others do not. Two concepts. namely. “premises” and should be smart and capable all the time.”
“schemata.” nicely fulfill the integrative function we ‘ ‘ Either-or’ assumptions
‘ that treat two separate
seek. premises as having equivalent meanings are also com-
Premises are implicit or explicit statements of fact mon among depressed individuals, for example. Ei- ‘ ‘
that form the basis or cornerstone of an argument. ther I am one hundred percent successful in everything
conclusion, evaluation, or problem-solving strategy. or I am a failure.’ ‘If I am not a success,
‘ ‘ life has no
Wason and Johnson-Laird (18) have suggested that meaning,” “If I am not loved by everyone, I cannot go
everyday problem solving is best understood as a func- on living.” In collaboration with us. Weissman con-
tion of “emotional decisions to accept or reject prem- structed the Dysfunctional Attitude Scale (DAS).
ises.” We have already noted the patient who eval- which contains statements reflecting a variety of both
uated the missed phone call from her boyfriend as a adaptive and maladaptive attitudes and beliefs. The
rejection and pointed out her arbitrary inference and maladaptive statements had been found to be charac-
personalized, negatively referential meaning. From a teristic of depressed patients in therapy but generally
clinical viewpoint, her conclusion that her boyfriend uncharacteristic of nondepressed patients. A high
did not want to see her any more was erroneous be- DAS score indicates endorsement of a large number of
cause it was not based on any evidence. The con- items that reflect depressogenic attitudes. In a pilot
clusion was also maladaptive because it led to in- study with 35 depressed psychiatric outpatients,
creased dysphoria. lack of activity for the duration of Weissman found a correlation coefficient of .58 be-
the evening, and continued rumination about her alleg- tween the DAS score and level of depression. Weiss-
edly poor interpersonal skills. Nevertheless, the inter- man is currently analyzing the reliability and validity
pretation was a natural function of the patient’s basic of the DAS using large samples of college students and
premise, namely. “If I am not important to everyone, I psychiatric patients.’
can’t go on living.” This patient defined being “impor- Silent assumptions or premises. bits of information,
tant to others” as other people attending to her, wor- and conclusions provide the content of a cognitive
rying about her, and always following through with schema. A schema is a relatively enduring structure
promises and commitments. that functions like a template; it actively screens,
We use the terms “silent assumptions,” “for-
‘For further information and copies of the DAS. write to Arlene
mulas,” and “basic equations” to refer to the prem- Weissman, American Board of Internal Medicine. 3930 Chestnut
ises that are crucial in depression. While depressive St., Philadelphia. Pa. 19104.
528
Am J Psychiatry /35:5, May 1978 MARIA KOVACS AND AARON T. BECK
codes, categorizes. and evaluates information. By def- pressed. One defining characteristic is inflexible or ab-
inition, it also represents some relevant prior experi- solute rules of conduct and evaluation that become
ence (16). manifest in the patient’s language as rigid quantifiers
(e.g. ,‘all,’ ‘ ‘always,”
‘ ‘ ‘never’ ‘), categorical
‘ impera-
tives (“must,’ ‘ought,” ‘ ‘have
‘ to’ ‘), and preemptive
‘
529
MALADAPTIVE COGNITIVE STRUCTURES Am J Ps chiatrv 135:5, May 1978
cable loss, such as the disruption of an interpersonal which show that depressed patients more often experi-
relationship. enced childhood bereavement than comparison groups
In repeated episodes of depression the same nega- did may lend some credence to this assumption (2).
tive cognitive schemata can be discerned in the pro- However, since these findings describe only a small
fusion of distorted cognitions and in blatant ex- number of all depressed patients. it is obvious that oth-
pressions of regret over unattainable goals or ex- er predisposing factors need to be explored.
pectations. When the patient is confronted with a Other factors important in the development of
perceived anticipated rejection. failure, or loss, the re- depressogenic schemata may include a parent whose
activation of the depressogenic schemata gradually own belief system revolves around personal in-
leads to the other classic symptoms of depression (2). adequacy or a parent whose constructive system en-
Insofar as these schemata appear to be long-term psy- compasses inflexible and rigid rules ofconduct. Thus a
chological templates associated with fairly stereo- young person may learn and develop some maladap-
typical attitudinal and behavioral responses under cer- tive schemata on the basis of modeling and social iden-
tam stimulus conditions, they may well constitute a tification. Such social processes can be reinforced by
cognitive dimension of the depression-prone individ- the parent or parenting one. For example. in family
ual’s personality. The central assumption ofthe cogni- therapy sessions it is not uncommon to observe a par-
tive approach to depression, namely, that cognition ent who derogates herself or himself for self-perceived
can determine affect, is supported by a growing body inadequacies and later expresses love for the child by
ofliterature. The literature documents that even in lab- saying, “He isjust like me.”
oratory settings. mood and behavior changes can be As already noted, according to our clinical experi-
induced through cognitive manipulations (47-5 1). ence the negative schemata that are dramatically oper-
Patients’ self-reports appear to support the clinical ative in the depressive episode seem to have been re-
observation that depressogenic schemata are probably fractory to ordinary change and reality testing. Thus
long-term . characteristic attitudes and problem-solv- what makes these schemata remarkable is probably
ing approaches. More to the point is a recent study by not their uniqueness in the depression-prone person’s
Hauri (52), supporting earlier work by Beck (2), both development, but the individual’s lack of opportunity
of which document that the content of depressed pa- or lack of experience in submitting them to examina-
tients’ dreams is consistent with their waking cogni- tion.
tions, i.e. , the dreams are dominated by themes of Since depressogenic cognitive structures generally
being rejected. thwarted. abandoned, ill, punished, un- relate to interpersonal conduct and evaluation, a num-
desirable, and ugly. Using a dream laboratory to col- ber of factors can militate against reality-testing them.
lect dreams from normal subjects and remitted de- A deficit in the child’s or young person’s social skills
pressed patients, Hauri (52) also found that, compared or negative interactions with peers or siblings may mil-
with the dreams of control subjects, even the dreams itate against social testing and reassessment of early
of remitted patients showed a preponderance of nega- interpretations. A young person’s self-construction of
tive themes. Moreover, remitted depressed patients “differentness.” derived from an actual or imagined
dreamed more about the past than normal controls did, physical defect, childhood obesity, natural shyness, or
which reflects the depressive tendency for selective fo- the like, may also hinder the testing or modification of
cus on past events. socially and interpersonally oriented schemata.
Thus certain cognitive processes seem chronically
atypical among depressed patients and may represent
a stable characteristic of their personality. This hy- CLINICAL MODIFICATION OF MALADAPTIVE
pothesis is partly supported by data on the relative sta- COGNITIVE SCHEMATA
bility of cognitive factors compared with affective fac-
tors. These data were reported by Weintraub and asso- Although cognitive structures appear to have some
ciates (33), who investigated cognition and affect over of the characteristics of personality traits, they can be
a two-month period. Cognitive content that was as- modified. In fact, since normal maturation encompass-
sessed through multiple-choice responses to a story es increasing knowledge and awareness of oneself and
completion task was found to be significantly inter- the milieu, the modification of cognitive schemata and
correlated over five testings. On the other hand, affect modulation of behavior are probably the norm rather
(assessed through the Multiple Affect Adjective Check than the exception.
List) was considerably less consistent over time. Fur- We have effectively used short-term cognitive thera-
thermore, changes in cognitive content appeared to py (2. 26) to treat outpatients with both minor and ma-
precede changes in affect. jor (nonpsychotic) unipolar depression. Cognitive
What factors and situations potentiate the develop- therapy is structured and directive, yet requires the
ment of depressogenic schemata? It has been sug- patient’s active collaboration. It encompasses the use
gested that the loss of a parent during one’s childhood of both verbal and behavioral techniques to alleviate
may have etiological significance (2). A set of premises depressive symptoms. In the initial treatment sessions
may evolve to guide the person’s eventual inter- we often employ behavioral techniques such as list-
pretation of losses as irreversible and traumatic. Data keeping, planning productive activities, and sched-
530
Am J Psvchiatiy 135:5, May /978 MARIA KOVACS AND AARON T. BECK
depression. confirmed by high scores on both self- and clini- ings. The possibility
‘ ‘ of being called upon at a meeting acti-
cal-rating scales of depression. Diagnostically. he satisfied vated Mr. D. ‘5 interpersonal schema concerned with dis-
the criteria for primary depression of the major unipolar approval. which led, in turn, to the cognition that if he did
(nonpsychotic) type. Mr. D. had a 10-year history of chronic speak up. he would make a fool of himself. Subsequent to
depression with periodic exacerbations. His current depres- the uncovering of Mr. D. s ‘ depressogenic schemata. treat-
sive episode coincided with a promotion and was reinforced ment focused on questioning their relevance and plausibility
by long-standing marital problems. and having Mr. D. test out new, alternative behaviors and
In the first phase of treatment the patient learned to mon- interpretations.
itor and record his negative automatic thoughts associated By testing and modifying the dysfunctional premises. the
with dysphoria. The following three self-observations were patient was helped to process. in a more realistic way. infor-
typical: “I’m unable to respond to my wife emotionally,” mation regarding other people’s reactions to him. One tech-
“I’m alienated from my family.” “I’m responsible for my nique that demonstrated the inappropriateness of his system
wife’s depression.” In the next phase of treatment these of assumptions consisted of Mr. D. ‘s adopting behaviors that
kinds of negative thoughts were grouped in order to abstract were contrary to his dysfunctional beliefs, for example, be-
general cognitive themes. As the cognitions cited above re- having as if the assumption that he needed the approval of
flect, one theme concerned Mr. D.’s self-perceived in- other people were untrue. The consequences of such “new”
adequacy in the roles of husband and father. As therapy behaviors led to an increase in more reality-oriented adapt-
progressed the therapist sought to elicit the meaning of Mr. ive cognitions.2
D. ‘s presumed inadequate performance in the family. Ac-
cording to the patient, the above observations indicated that
he was “emotionally empty” and a miserable person who
EFFICACY OF COGNITIVE THERAPY
had “nothing to give.” The theme of interpersonal self-dero-
gation was subsequently also abstracted from his distorted
A recent empirical study by Rush and associ-
cognitive responses to his relationships with other people in
various settings. To be interpersonally incompetent meant ates (53) assessed the efficacy of cognitive therapy,
that he was “unworthy.” Underlying all of the patient’s de- compared with pharmacotherapy, in the treatment of
pressive cognitions was the basic formula that if he did not depressed outpatients. Forty-one unipolar depressed
live up to his own idiosyncratic expectations of perfection outpatients randomly assigned to either cognitive ther-
(which he unquestioningly believed everyone shared), other apy (N= 19) or imipramine treatment (N =22) were
people “would not approve” of him.
After considerable questioning and trial-and-error “fit-
2Other techniques are described in detail in a new manual on the
ting,” the therapist and patient were able to derive a mean- cognitive therapy of depression by Beck and associates. The un-
ingful chain of assumptions and premises (see figure 1). published manual is available from Dr. Beck: his address is 133
The patient’s underlying belief that he did not have “the South 36th St.. Room 602, Philadelphia, Pa. 19104.
531
MALADAPTIVE COGNITIVE STRUCTURES Am J Psychiatry 135:5, May 1978
532
Am J Psychiatry 135:5, May 1978 MARIA KOVACS AND AARON T. BECK
Dis 152:106-114, 1971 the initial interview. J Consult Clin Psychol 45:45-52, 1977
47. Coleman RE: Manipulation of self-esteem as a determinant of 51. Velten E: A laboratory task for induction of mood states. Behav
mood of elated and depressed women. J Abnorm Psychol Res Then 6:473-482, 1968
84:693-700, 1975 52. Hauni P: Dreams in patients remitted from reactive depression.
48. Ludwig LD: Elation-depression and skill as determinants of de- J Abnorm Psychol 85: 1-10, 1976
sire for excitement. J Pens 43:1-22, 1975 53. Rush AJ, Beck AT. Kovacs M. et al: Comparative efficacy of
49. Moore BS, Underwood B, Rosenhan DL: Affect and altruism. cognitive therapy and pharmacothenapy in the treatment of de-
Developmental Psychology 8:99-104. 1973 pressed outpatients. Cognitive Therapy and Research 1:17-37,
50. Natale M: Effects of induced elation-depression on speech in 1977
This issue of the Journal introduces a greatly expanded “Information for Contributors.”
which contains important information for authors and Journal readers. The section clari-
fies many Journal policies and style points, and includes some important changes. such as
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scripts. 2) the option of early submission of annual meeting papers. and 3) specific guide-
lines for writing, typing. and arranging the paper. Failure to fulfill the stated criteria can
result in delays in the review process. Contributors a1e also urged to read the sections
regarding accepted manuscripts, which contain important information regarding the publi-
cation process. reprints, etc.
533