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Variable TK

Classification variable GDS

Sample size 264


Positive group : GDS = 1 46
Negative group : GDS = 0 218

Disease prevalence (%) unknown


Area under the ROC curve (AUC)

Area under the ROC curve (AUC) 0.542


Standard Errora 0.0458
95% Confidence intervalb 0.480 to 0.603
z statistic 0.914
Significance level P (Area=0.5) 0.3609
a
DeLong et al., 1988
b
Binomial exact

Youden index

Youden index J 0.1488


Associated criterion >202
Criterion values and coordinates of the ROC curve [Hide]

Criterion Sensitivity 95% CI Specificity 95% CI +LR -LR


≥100 100.00 92.3 - 100.0 0.00 0.0 - 1.7 1.00
>113 100.00 92.3 - 100.0 3.67 1.6 - 7.1 1.04 0.00
>115 97.83 88.5 - 99.9 4.13 1.9 - 7.7 1.02 0.53
>140 97.83 88.5 - 99.9 11.93 7.9 - 17.0 1.11 0.18
>141 95.65 85.2 - 99.5 12.39 8.3 - 17.5 1.09 0.35
>147 95.65 85.2 - 99.5 12.84 8.7 - 18.0 1.10 0.34
>148 93.48 82.1 - 98.6 13.76 9.5 - 19.1 1.08 0.47
>154 93.48 82.1 - 98.6 16.97 12.2 - 22.6 1.13 0.38
>155 91.30 79.2 - 97.6 17.43 12.6 - 23.1 1.11 0.50
>156 89.13 76.4 - 96.4 17.43 12.6 - 23.1 1.08 0.62
>157 89.13 76.4 - 96.4 17.89 13.0 - 23.6 1.09 0.61
>158 86.96 73.7 - 95.1 17.89 13.0 - 23.6 1.06 0.73
>159 84.78 71.1 - 93.7 18.35 13.4 - 24.1 1.04 0.83
>164 84.78 71.1 - 93.7 20.18 15.1 - 26.1 1.06 0.75
>166 82.61 68.6 - 92.2 20.64 15.5 - 26.6 1.04 0.84
>168 80.43 66.1 - 90.6 21.10 15.9 - 27.1 1.02 0.93
>169 78.26 63.6 - 89.1 22.48 17.1 - 28.6 1.01 0.97
>170 78.26 63.6 - 89.1 23.85 18.4 - 30.1 1.03 0.91
>171 76.09 61.2 - 87.4 24.31 18.8 - 30.6 1.01 0.98
>173 76.09 61.2 - 87.4 26.15 20.4 - 32.5 1.03 0.91
>174 73.91 58.9 - 85.7 27.06 21.3 - 33.5 1.01 0.96
>175 73.91 58.9 - 85.7 28.44 22.6 - 34.9 1.03 0.92
>176 71.74 56.5 - 84.0 28.44 22.6 - 34.9 1.00 0.99
>177 71.74 56.5 - 84.0 28.90 23.0 - 35.4 1.01 0.98
>178 69.57 54.2 - 82.3 30.73 24.7 - 37.3 1.00 0.99
>179 67.39 52.0 - 80.5 31.65 25.5 - 38.3 0.99 1.03
>182 67.39 52.0 - 80.5 36.24 29.9 - 43.0 1.06 0.90
>183 65.22 49.8 - 78.6 36.70 30.3 - 43.5 1.03 0.95
>184 63.04 47.5 - 76.8 37.61 31.2 - 44.4 1.01 0.98
>202 63.04 47.5 - 76.8 51.83 45.0 - 58.6 1.31 0.71
>203 60.87 45.4 - 74.9 53.21 46.4 - 60.0 1.30 0.74
>204 54.35 39.0 - 69.1 53.21 46.4 - 60.0 1.16 0.86
>205 54.35 39.0 - 69.1 55.05 48.2 - 61.8 1.21 0.83
>206 52.17 36.9 - 67.1 55.50 48.6 - 62.2 1.17 0.86
>207 50.00 34.9 - 65.1 55.50 48.6 - 62.2 1.12 0.90
>209 47.83 32.9 - 63.1 56.42 49.6 - 63.1 1.10 0.92
>210 47.83 32.9 - 63.1 57.80 50.9 - 64.4 1.13 0.90
>211 45.65 30.9 - 61.0 59.63 52.8 - 66.2 1.13 0.91
>212 43.48 28.9 - 58.9 60.55 53.7 - 67.1 1.10 0.93
>213 43.48 28.9 - 58.9 61.93 55.1 - 68.4 1.14 0.91
>214 41.30 27.0 - 56.8 63.30 56.5 - 69.7 1.13 0.93
>217 41.30 27.0 - 56.8 66.06 59.4 - 72.3 1.22 0.89
>218 39.13 25.1 - 54.6 66.97 60.3 - 73.2 1.18 0.91
>222 39.13 25.1 - 54.6 69.27 62.7 - 75.3 1.27 0.88
>223 36.96 23.2 - 52.5 69.27 62.7 - 75.3 1.20 0.91
>229 36.96 23.2 - 52.5 72.94 66.5 - 78.7 1.37 0.86
>230 30.43 17.7 - 45.8 73.85 67.5 - 79.6 1.16 0.94
>231 28.26 16.0 - 43.5 74.77 68.5 - 80.4 1.12 0.96
>232 26.09 14.3 - 41.1 75.23 68.9 - 80.8 1.05 0.98
>238 26.09 14.3 - 41.1 78.44 72.4 - 83.7 1.21 0.94
>240 23.91 12.6 - 38.8 79.36 73.4 - 84.5 1.16 0.96
>244 23.91 12.6 - 38.8 81.19 75.4 - 86.2 1.27 0.94
>245 21.74 10.9 - 36.4 81.65 75.9 - 86.6 1.18 0.96
>249 21.74 10.9 - 36.4 83.03 77.4 - 87.8 1.28 0.94
>252 19.57 9.4 - 33.9 84.40 78.9 - 89.0 1.25 0.95
>253 15.22 6.3 - 28.9 85.32 79.9 - 89.7 1.04 0.99
>254 13.04 4.9 - 26.3 85.78 80.4 - 90.1 0.92 1.01
>256 13.04 4.9 - 26.3 86.24 80.9 - 90.5 0.95 1.01
>257 10.87 3.6 - 23.6 86.70 81.5 - 90.9 0.82 1.03
>259 8.70 2.4 - 20.8 86.70 81.5 - 90.9 0.65 1.05
>266 8.70 2.4 - 20.8 89.91 85.1 - 93.6 0.86 1.02
>267 6.52 1.4 - 17.9 90.37 85.7 - 93.9 0.68 1.03
>274 6.52 1.4 - 17.9 92.20 87.8 - 95.4 0.84 1.01
>276 4.35 0.5 - 14.8 92.20 87.8 - 95.4 0.56 1.04
>304 4.35 0.5 - 14.8 97.25 94.1 - 99.0 1.58 0.98
>305 2.17 0.06 - 11.5 97.25 94.1 - 99.0 0.79 1.01
>308 2.17 0.06 - 11.5 97.71 94.7 - 99.3 0.95 1.00
>316 0.00 0.0 - 7.7 98.62 96.0 - 99.7 0.00 1.01
>346 0.00 0.0 - 7.7 100.00 98.3 - 100.0 1.00
Variable TG
Classification variable GDS

Sample size 264


Positive group : GDS = 1 46
Negative group : GDS = 0 218

Disease prevalence (%) unknown


Area under the ROC curve (AUC)

Area under the ROC curve (AUC) 0.570


Standard Errora 0.0467
95% Confidence intervalb 0.507 to 0.630
z statistic 1.491
Significance level P (Area=0.5) 0.1358
a
DeLong et al., 1988
b
Binomial exact

Youden index
Youden index J 0.1500
Associated criterion >139
Criterion values and coordinates of the ROC curve [Hide]

Criterion Sensitivity 95% CI Specificity 95% CI +LR -LR


≥49 100.00 92.3 - 100.0 0.00 0.0 - 1.7 1.00
>49 97.83 88.5 - 99.9 0.00 0.0 - 1.7 0.98
>77 97.83 88.5 - 99.9 6.42 3.6 - 10.5 1.05 0.34
>80 95.65 85.2 - 99.5 6.88 3.9 - 11.1 1.03 0.63
>87 95.65 85.2 - 99.5 8.72 5.3 - 13.3 1.05 0.50
>88 91.30 79.2 - 97.6 9.17 5.7 - 13.8 1.01 0.95
>98 91.30 79.2 - 97.6 15.60 11.0 - 21.1 1.08 0.56
>99 89.13 76.4 - 96.4 15.60 11.0 - 21.1 1.06 0.70
>102 89.13 76.4 - 96.4 17.89 13.0 - 23.6 1.09 0.61
>103 84.78 71.1 - 93.7 18.81 13.8 - 24.6 1.04 0.81
>104 84.78 71.1 - 93.7 19.27 14.3 - 25.1 1.05 0.79
>105 82.61 68.6 - 92.2 19.72 14.7 - 25.6 1.03 0.88
>106 80.43 66.1 - 90.6 20.64 15.5 - 26.6 1.01 0.95
>119 80.43 66.1 - 90.6 33.49 27.3 - 40.2 1.21 0.58
>120 78.26 63.6 - 89.1 34.40 28.1 - 41.1 1.19 0.63
>121 78.26 63.6 - 89.1 35.78 29.4 - 42.5 1.22 0.61
>122 76.09 61.2 - 87.4 35.78 29.4 - 42.5 1.18 0.67
>123 73.91 58.9 - 85.7 37.16 30.7 - 43.9 1.18 0.70
>124 73.91 58.9 - 85.7 38.07 31.6 - 44.9 1.19 0.69
>125 71.74 56.5 - 84.0 39.45 32.9 - 46.3 1.18 0.72
>126 71.74 56.5 - 84.0 40.37 33.8 - 47.2 1.20 0.70
>127 69.57 54.2 - 82.3 40.83 34.2 - 47.7 1.18 0.75
>128 67.39 52.0 - 80.5 41.28 34.7 - 48.1 1.15 0.79
>129 67.39 52.0 - 80.5 43.12 36.4 - 50.0 1.18 0.76
>130 63.04 47.5 - 76.8 44.95 38.2 - 51.8 1.15 0.82
>132 63.04 47.5 - 76.8 48.17 41.4 - 55.0 1.22 0.77
>133 60.87 45.4 - 74.9 49.54 42.7 - 56.4 1.21 0.79
>139 60.87 45.4 - 74.9 54.13 47.3 - 60.9 1.33 0.72
>140 56.52 41.1 - 71.1 55.05 48.2 - 61.8 1.26 0.79
>141 54.35 39.0 - 69.1 56.42 49.6 - 63.1 1.25 0.81
>142 52.17 36.9 - 67.1 56.88 50.0 - 63.6 1.21 0.84
>143 50.00 34.9 - 65.1 58.26 51.4 - 64.9 1.20 0.86
>144 47.83 32.9 - 63.1 59.63 52.8 - 66.2 1.18 0.87
>147 47.83 32.9 - 63.1 61.93 55.1 - 68.4 1.26 0.84
>148 45.65 30.9 - 61.0 62.39 55.6 - 68.8 1.21 0.87
>149 43.48 28.9 - 58.9 64.68 57.9 - 71.0 1.23 0.87
>150 41.30 27.0 - 56.8 66.51 59.8 - 72.7 1.23 0.88
>151 39.13 25.1 - 54.6 67.43 60.8 - 73.6 1.20 0.90
>153 39.13 25.1 - 54.6 68.81 62.2 - 74.9 1.25 0.88
>154 34.78 21.4 - 50.2 71.10 64.6 - 77.0 1.20 0.92
>155 32.61 19.5 - 48.0 72.02 65.6 - 77.9 1.17 0.94
>158 32.61 19.5 - 48.0 74.31 68.0 - 80.0 1.27 0.91
>159 30.43 17.7 - 45.8 75.69 69.4 - 81.2 1.25 0.92
>164 30.43 17.7 - 45.8 79.82 73.9 - 84.9 1.51 0.87
>165 28.26 16.0 - 43.5 80.73 74.9 - 85.7 1.47 0.89
>167 28.26 16.0 - 43.5 82.11 76.4 - 87.0 1.58 0.87
>168 26.09 14.3 - 41.1 82.57 76.9 - 87.4 1.50 0.90
>169 26.09 14.3 - 41.1 83.49 77.9 - 88.2 1.58 0.89
>170 21.74 10.9 - 36.4 83.49 77.9 - 88.2 1.32 0.94
>177 21.74 10.9 - 36.4 84.86 79.4 - 89.3 1.44 0.92
>178 17.39 7.8 - 31.4 85.78 80.4 - 90.1 1.22 0.96
>184 17.39 7.8 - 31.4 91.28 86.7 - 94.7 2.00 0.90
>186 15.22 6.3 - 28.9 91.28 86.7 - 94.7 1.75 0.93
>187 13.04 4.9 - 26.3 92.20 87.8 - 95.4 1.67 0.94
>190 10.87 3.6 - 23.6 93.12 88.9 - 96.1 1.58 0.96
>194 8.70 2.4 - 20.8 93.58 89.5 - 96.4 1.35 0.98
>202 8.70 2.4 - 20.8 95.41 91.7 - 97.8 1.90 0.96
>204 6.52 1.4 - 17.9 95.41 91.7 - 97.8 1.42 0.98
>208 6.52 1.4 - 17.9 96.79 93.5 - 98.7 2.03 0.97
>209 4.35 0.5 - 14.8 96.79 93.5 - 98.7 1.35 0.99
>214 4.35 0.5 - 14.8 97.25 94.1 - 99.0 1.58 0.98
>218 2.17 0.06 - 11.5 97.25 94.1 - 99.0 0.79 1.01
>226 2.17 0.06 - 11.5 98.62 96.0 - 99.7 1.58 0.99
>232 0.00 0.0 - 7.7 98.62 96.0 - 99.7 0.00 1.01
>303 0.00 0.0 - 7.7 100.00 98.3 - 100.0 1.00

Variable LDL
Classification variable GDS

Sample size 264


Positive group : GDS = 1 46
Negative group : GDS = 0 218

Disease prevalence (%) unknown


Area under the ROC curve (AUC)

Area under the ROC curve (AUC) 0.543


Standard Errora 0.0460
95% Confidence intervalb 0.481 to 0.605
z statistic 0.941
Significance level P (Area=0.5) 0.3466
a
DeLong et al., 1988
b
Binomial exact

Youden index

Youden index J 0.1316


Associated criterion >135
Criterion values and coordinates of the ROC curve [Hide]
Criterion Sensitivity 95% CI Specificity 95% CI +LR -LR
≥37 100.00 92.3 - 100.0 0.00 0.0 - 1.7 1.00
>73 100.00 92.3 - 100.0 4.13 1.9 - 7.7 1.04 0.00
>74 97.83 88.5 - 99.9 4.13 1.9 - 7.7 1.02 0.53
>84 97.83 88.5 - 99.9 8.72 5.3 - 13.3 1.07 0.25
>87 95.65 85.2 - 99.5 9.17 5.7 - 13.8 1.05 0.47
>92 95.65 85.2 - 99.5 12.84 8.7 - 18.0 1.10 0.34
>93 93.48 82.1 - 98.6 13.30 9.1 - 18.5 1.08 0.49
>94 93.48 82.1 - 98.6 13.76 9.5 - 19.1 1.08 0.47
>98 91.30 79.2 - 97.6 13.76 9.5 - 19.1 1.06 0.63
>99 91.30 79.2 - 97.6 14.68 10.3 - 20.1 1.07 0.59
>100 89.13 76.4 - 96.4 15.60 11.0 - 21.1 1.06 0.70
>102 89.13 76.4 - 96.4 17.89 13.0 - 23.6 1.09 0.61
>104 86.96 73.7 - 95.1 18.35 13.4 - 24.1 1.06 0.71
>106 84.78 71.1 - 93.7 19.72 14.7 - 25.6 1.06 0.77
>108 84.78 71.1 - 93.7 21.10 15.9 - 27.1 1.07 0.72
>109 82.61 68.6 - 92.2 22.02 16.7 - 28.1 1.06 0.79
>111 82.61 68.6 - 92.2 24.77 19.2 - 31.1 1.10 0.70
>112 80.43 66.1 - 90.6 25.69 20.0 - 32.0 1.08 0.76
>113 78.26 63.6 - 89.1 26.61 20.9 - 33.0 1.07 0.82
>114 78.26 63.6 - 89.1 27.06 21.3 - 33.5 1.07 0.80
>115 73.91 58.9 - 85.7 27.98 22.1 - 34.4 1.03 0.93
>117 73.91 58.9 - 85.7 31.19 25.1 - 37.8 1.07 0.84
>118 69.57 54.2 - 82.3 31.65 25.5 - 38.3 1.02 0.96
>119 69.57 54.2 - 82.3 33.94 27.7 - 40.6 1.05 0.90
>120 67.39 52.0 - 80.5 33.94 27.7 - 40.6 1.02 0.96
>121 65.22 49.8 - 78.6 34.86 28.6 - 41.6 1.00 1.00
>122 60.87 45.4 - 74.9 35.78 29.4 - 42.5 0.95 1.09
>135 60.87 45.4 - 74.9 52.29 45.4 - 59.1 1.28 0.75
>136 56.52 41.1 - 71.1 53.21 46.4 - 60.0 1.21 0.82
>137 56.52 41.1 - 71.1 53.67 46.8 - 60.4 1.22 0.81
>138 54.35 39.0 - 69.1 54.59 47.7 - 61.3 1.20 0.84
>139 54.35 39.0 - 69.1 56.42 49.6 - 63.1 1.25 0.81
>140 52.17 36.9 - 67.1 57.80 50.9 - 64.4 1.24 0.83
>141 45.65 30.9 - 61.0 58.72 51.9 - 65.3 1.11 0.93
>142 45.65 30.9 - 61.0 59.63 52.8 - 66.2 1.13 0.91
>143 41.30 27.0 - 56.8 61.01 54.2 - 67.5 1.06 0.96
>147 41.30 27.0 - 56.8 66.51 59.8 - 72.7 1.23 0.88
>148 39.13 25.1 - 54.6 66.97 60.3 - 73.2 1.18 0.91
>150 39.13 25.1 - 54.6 68.35 61.7 - 74.5 1.24 0.89
>151 36.96 23.2 - 52.5 69.72 63.2 - 75.7 1.22 0.90
>153 36.96 23.2 - 52.5 72.94 66.5 - 78.7 1.37 0.86
>154 34.78 21.4 - 50.2 74.31 68.0 - 80.0 1.35 0.88
>155 32.61 19.5 - 48.0 74.77 68.5 - 80.4 1.29 0.90
>156 30.43 17.7 - 45.8 75.23 68.9 - 80.8 1.23 0.92
>157 28.26 16.0 - 43.5 76.61 70.4 - 82.1 1.21 0.94
>159 28.26 16.0 - 43.5 78.44 72.4 - 83.7 1.31 0.91
>160 23.91 12.6 - 38.8 79.36 73.4 - 84.5 1.16 0.96
>162 21.74 10.9 - 36.4 79.36 73.4 - 84.5 1.05 0.99
>163 19.57 9.4 - 33.9 79.82 73.9 - 84.9 0.97 1.01
>165 19.57 9.4 - 33.9 83.03 77.4 - 87.8 1.15 0.97
>167 17.39 7.8 - 31.4 83.94 78.4 - 88.6 1.08 0.98
>171 17.39 7.8 - 31.4 86.70 81.5 - 90.9 1.31 0.95
>172 15.22 6.3 - 28.9 86.70 81.5 - 90.9 1.14 0.98
>173 13.04 4.9 - 26.3 87.16 82.0 - 91.3 1.02 1.00
>175 13.04 4.9 - 26.3 87.61 82.5 - 91.7 1.05 0.99
>177 10.87 3.6 - 23.6 88.07 83.0 - 92.1 0.91 1.01
>178 8.70 2.4 - 20.8 88.07 83.0 - 92.1 0.73 1.04
>183 8.70 2.4 - 20.8 90.37 85.7 - 93.9 0.90 1.01
>185 6.52 1.4 - 17.9 90.37 85.7 - 93.9 0.68 1.03
>187 6.52 1.4 - 17.9 91.74 87.3 - 95.0 0.79 1.02
>188 4.35 0.5 - 14.8 91.74 87.3 - 95.0 0.53 1.04
>216 4.35 0.5 - 14.8 98.62 96.0 - 99.7 3.16 0.97
>225 2.17 0.06 - 11.5 99.08 96.7 - 99.9 2.37 0.99
>231 2.17 0.06 - 11.5 99.54 97.5 - 100.0 4.74 0.98
>277 0.00 0.0 - 7.7 99.54 97.5 - 100.0 0.00 1.00
>348 0.00 0.0 - 7.7 100.00 98.3 - 100.0 1.00

Variable HDL
Classification variable GDS

Sample size 264


Positive group : GDS = 1 46
Negative group : GDS = 0 218

Disease prevalence (%) unknown


Area under the ROC curve (AUC)

Area under the ROC curve (AUC) 0.543


Standard Errora 0.0428
95% Confidence intervalb 0.481 to 0.605
z statistic 1.011
Significance level P (Area=0.5) 0.3119
a
DeLong et al., 1988
b
Binomial exact

Youden index

Youden index J 0.1434


Associated criterion ≤35
Criterion values and coordinates of the ROC curve [Hide]

Criterion Sensitivity 95% CI Specificity 95% CI +LR -LR


<21 0.00 0.0 - 7.7 100.00 98.3 - 100.0 1.00
≤26 0.00 0.0 - 7.7 97.25 94.1 - 99.0 0.00 1.03
≤27 2.17 0.06 - 11.5 97.25 94.1 - 99.0 0.79 1.01
≤30 2.17 0.06 - 11.5 88.07 83.0 - 92.1 0.18 1.11
≤31 4.35 0.5 - 14.8 84.40 78.9 - 89.0 0.28 1.13
≤32 10.87 3.6 - 23.6 81.65 75.9 - 86.6 0.59 1.09
≤33 15.22 6.3 - 28.9 76.15 69.9 - 81.6 0.64 1.11
≤34 30.43 17.7 - 45.8 73.85 67.5 - 79.6 1.16 0.94
≤35 47.83 32.9 - 63.1 66.51 59.8 - 72.7 1.43 0.78
≤36 52.17 36.9 - 67.1 55.05 48.2 - 61.8 1.16 0.87
≤37 60.87 45.4 - 74.9 48.62 41.8 - 55.5 1.18 0.80
≤38 65.22 49.8 - 78.6 42.20 35.6 - 49.1 1.13 0.82
≤39 73.91 58.9 - 85.7 38.53 32.0 - 45.3 1.20 0.68
≤40 76.09 61.2 - 87.4 33.03 26.8 - 39.7 1.14 0.72
≤41 80.43 66.1 - 90.6 27.98 22.1 - 34.4 1.12 0.70
≤42 84.78 71.1 - 93.7 21.10 15.9 - 27.1 1.07 0.72
≤43 89.13 76.4 - 96.4 17.89 13.0 - 23.6 1.09 0.61
≤44 91.30 79.2 - 97.6 14.22 9.9 - 19.6 1.06 0.61
≤45 93.48 82.1 - 98.6 12.39 8.3 - 17.5 1.07 0.53
≤46 95.65 85.2 - 99.5 11.47 7.6 - 16.5 1.08 0.38
≤48 95.65 85.2 - 99.5 10.55 6.8 - 15.4 1.07 0.41
≤49 97.83 88.5 - 99.9 10.09 6.4 - 14.9 1.09 0.22
≤67 97.83 88.5 - 99.9 5.05 2.5 - 8.8 1.03 0.43
≤69 100.00 92.3 - 100.0 4.59 2.2 - 8.3 1.05 0.00
≤196 100.00 92.3 - 100.0 0.00 0.0 - 1.7 1.00
Variable KT
Classification variable GDS

Sample size 283


Positive group : GDS = 1 65
Negative group : GDS = 0 218

Disease prevalence (%) unknown


Area under the ROC curve (AUC)

Area under the ROC curve (AUC) 0.580


Standard Errora 0.0365
95% Confidence intervalb 0.520 to 0.638
z statistic 2.189
Significance level P (Area=0.5) 0.0286
a
DeLong et al., 1988
b
Binomial exact

Youden index
Youden index J 0.2342
Associated criterion >190
Criterion values and coordinates of the ROC curve [Hide]

Criterion Sensitivity 95% CI Specificity 95% CI +LR -LR


≥100 100.00 94.5 - 100.0 0.00 0.0 - 1.7 1.00
>141 100.00 94.5 - 100.0 12.39 8.3 - 17.5 1.14 0.00
>145 95.38 87.1 - 99.0 12.39 8.3 - 17.5 1.09 0.37
>147 93.85 85.0 - 98.3 12.84 8.7 - 18.0 1.08 0.48
>150 93.85 85.0 - 98.3 15.14 10.7 - 20.6 1.11 0.41
>152 92.31 83.0 - 97.5 16.06 11.4 - 21.6 1.10 0.48
>155 92.31 83.0 - 97.5 17.43 12.6 - 23.1 1.12 0.44
>156 90.77 81.0 - 96.5 17.43 12.6 - 23.1 1.10 0.53
>160 90.77 81.0 - 96.5 18.81 13.8 - 24.6 1.12 0.49
>161 89.23 79.1 - 95.6 18.81 13.8 - 24.6 1.10 0.57
>164 89.23 79.1 - 95.6 20.18 15.1 - 26.1 1.12 0.53
>166 87.69 77.2 - 94.5 20.64 15.5 - 26.6 1.11 0.60
>173 87.69 77.2 - 94.5 26.15 20.4 - 32.5 1.19 0.47
>174 86.15 75.3 - 93.5 27.06 21.3 - 33.5 1.18 0.51
>175 86.15 75.3 - 93.5 28.44 22.6 - 34.9 1.20 0.49
>176 84.62 73.5 - 92.4 28.44 22.6 - 34.9 1.18 0.54
>177 84.62 73.5 - 92.4 28.90 23.0 - 35.4 1.19 0.53
>178 83.08 71.7 - 91.2 30.73 24.7 - 37.3 1.20 0.55
>182 83.08 71.7 - 91.2 36.24 29.9 - 43.0 1.30 0.47
>183 81.54 70.0 - 90.1 36.70 30.3 - 43.5 1.29 0.50
>184 80.00 68.2 - 88.9 37.61 31.2 - 44.4 1.28 0.53
>188 80.00 68.2 - 88.9 41.28 34.7 - 48.1 1.36 0.48
>189 78.46 66.5 - 87.7 43.58 36.9 - 50.4 1.39 0.49
>190 78.46 66.5 - 87.7 44.95 38.2 - 51.8 1.43 0.48
>191 76.92 64.8 - 86.5 45.41 38.7 - 52.3 1.41 0.51
>192 75.38 63.1 - 85.2 45.87 39.1 - 52.7 1.39 0.54
>195 75.38 63.1 - 85.2 47.25 40.5 - 54.1 1.43 0.52
>196 73.85 61.5 - 84.0 48.62 41.8 - 55.5 1.44 0.54
>199 72.31 59.8 - 82.7 49.08 42.3 - 55.9 1.42 0.56
>200 67.69 54.9 - 78.8 50.46 43.6 - 57.3 1.37 0.64
>202 67.69 54.9 - 78.8 51.83 45.0 - 58.6 1.41 0.62
>203 63.08 50.2 - 74.7 53.21 46.4 - 60.0 1.35 0.69
>205 63.08 50.2 - 74.7 55.05 48.2 - 61.8 1.40 0.67
>206 61.54 48.6 - 73.3 55.50 48.6 - 62.2 1.38 0.69
>208 52.31 39.5 - 64.9 55.50 48.6 - 62.2 1.18 0.86
>209 50.77 38.1 - 63.4 56.42 49.6 - 63.1 1.17 0.87
>212 50.77 38.1 - 63.4 60.55 53.7 - 67.1 1.29 0.81
>213 49.23 36.6 - 61.9 61.93 55.1 - 68.4 1.29 0.82
>214 46.15 33.7 - 59.0 63.30 56.5 - 69.7 1.26 0.85
>217 46.15 33.7 - 59.0 66.06 59.4 - 72.3 1.36 0.82
>218 44.62 32.3 - 57.5 66.97 60.3 - 73.2 1.35 0.83
>219 43.08 30.8 - 56.0 66.97 60.3 - 73.2 1.30 0.85
>220 41.54 29.4 - 54.4 67.43 60.8 - 73.6 1.28 0.87
>221 35.38 23.9 - 48.2 68.35 61.7 - 74.5 1.12 0.95
>222 35.38 23.9 - 48.2 69.27 62.7 - 75.3 1.15 0.93
>224 30.77 19.9 - 43.4 69.72 63.2 - 75.7 1.02 0.99
>226 30.77 19.9 - 43.4 71.56 65.1 - 77.4 1.08 0.97
>228 27.69 17.3 - 40.2 72.48 66.0 - 78.3 1.01 1.00
>232 27.69 17.3 - 40.2 75.23 68.9 - 80.8 1.12 0.96
>234 23.08 13.5 - 35.2 75.23 68.9 - 80.8 0.93 1.02
>235 20.00 11.1 - 31.8 76.15 69.9 - 81.6 0.84 1.05
>236 18.46 9.9 - 30.0 77.98 71.9 - 83.3 0.84 1.05
>238 18.46 9.9 - 30.0 78.44 72.4 - 83.7 0.86 1.04
>239 16.92 8.8 - 28.3 78.44 72.4 - 83.7 0.78 1.06
>241 16.92 8.8 - 28.3 80.73 74.9 - 85.7 0.88 1.03
>242 15.38 7.6 - 26.5 80.73 74.9 - 85.7 0.80 1.05
>244 15.38 7.6 - 26.5 81.19 75.4 - 86.2 0.82 1.04
>245 13.85 6.5 - 24.7 81.65 75.9 - 86.6 0.75 1.06
>246 12.31 5.5 - 22.8 82.11 76.4 - 87.0 0.69 1.07
>249 12.31 5.5 - 22.8 83.03 77.4 - 87.8 0.73 1.06
>251 10.77 4.4 - 20.9 83.03 77.4 - 87.8 0.63 1.07
>257 10.77 4.4 - 20.9 86.70 81.5 - 90.9 0.81 1.03
>260 9.23 3.5 - 19.0 87.61 82.5 - 91.7 0.75 1.04
>263 9.23 3.5 - 19.0 88.53 83.5 - 92.4 0.80 1.03
>264 7.69 2.5 - 17.0 88.53 83.5 - 92.4 0.67 1.04
>265 7.69 2.5 - 17.0 88.99 84.1 - 92.8 0.70 1.04
>266 6.15 1.7 - 15.0 89.91 85.1 - 93.6 0.61 1.04
>267 4.62 1.0 - 12.9 90.37 85.7 - 93.9 0.48 1.06
>268 3.08 0.4 - 10.7 90.37 85.7 - 93.9 0.32 1.07
>278 3.08 0.4 - 10.7 92.66 88.4 - 95.7 0.42 1.05
>281 1.54 0.04 - 8.3 92.66 88.4 - 95.7 0.21 1.06
>316 1.54 0.04 - 8.3 98.62 96.0 - 99.7 1.12 1.00
>319 0.00 0.0 - 5.5 98.62 96.0 - 99.7 0.00 1.01
>346 0.00 0.0 - 5.5 100.00 98.3 - 100.0 1.00

Variable TG
Classification variable GDS

Sample size 283


Positive group : GDS = 1 65
Negative group : GDS = 0 218

Disease prevalence (%) unknown


Area under the ROC curve (AUC)

Area under the ROC curve (AUC) 0.574


Standard Errora 0.0383
95% Confidence intervalb 0.514 to 0.632
z statistic 1.922
Significance level P (Area=0.5) 0.0546
a
DeLong et al., 1988
b
Binomial exact

Youden index
Youden index J 0.1880
Associated criterion >130
Criterion values and coordinates of the ROC curve [Hide]

Criterion Sensitivity 95% CI Specificity 95% CI +LR -LR


≥53 100.00 94.5 - 100.0 0.00 0.0 - 1.7 1.00
>71 100.00 94.5 - 100.0 3.67 1.6 - 7.1 1.04 0.00
>72 96.92 89.3 - 99.6 3.67 1.6 - 7.1 1.01 0.84
>83 96.92 89.3 - 99.6 7.34 4.3 - 11.6 1.05 0.42
>86 95.38 87.1 - 99.0 8.26 5.0 - 12.7 1.04 0.56
>87 93.85 85.0 - 98.3 8.72 5.3 - 13.3 1.03 0.71
>98 93.85 85.0 - 98.3 15.60 11.0 - 21.1 1.11 0.39
>99 92.31 83.0 - 97.5 15.60 11.0 - 21.1 1.09 0.49
>100 92.31 83.0 - 97.5 16.06 11.4 - 21.6 1.10 0.48
>101 90.77 81.0 - 96.5 16.51 11.8 - 22.1 1.09 0.56
>103 90.77 81.0 - 96.5 18.81 13.8 - 24.6 1.12 0.49
>104 89.23 79.1 - 95.6 19.27 14.3 - 25.1 1.11 0.56
>105 89.23 79.1 - 95.6 19.72 14.7 - 25.6 1.11 0.55
>106 87.69 77.2 - 94.5 20.64 15.5 - 26.6 1.11 0.60
>107 86.15 75.3 - 93.5 22.02 16.7 - 28.1 1.10 0.63
>110 86.15 75.3 - 93.5 24.31 18.8 - 30.6 1.14 0.57
>111 84.62 73.5 - 92.4 24.31 18.8 - 30.6 1.12 0.63
>115 84.62 73.5 - 92.4 28.90 23.0 - 35.4 1.19 0.53
>116 83.08 71.7 - 91.2 31.19 25.1 - 37.8 1.21 0.54
>118 83.08 71.7 - 91.2 32.11 26.0 - 38.7 1.22 0.53
>119 81.54 70.0 - 90.1 33.49 27.3 - 40.2 1.23 0.55
>121 81.54 70.0 - 90.1 35.78 29.4 - 42.5 1.27 0.52
>122 80.00 68.2 - 88.9 35.78 29.4 - 42.5 1.25 0.56
>123 78.46 66.5 - 87.7 37.16 30.7 - 43.9 1.25 0.58
>125 78.46 66.5 - 87.7 39.45 32.9 - 46.3 1.30 0.55
>126 75.38 63.1 - 85.2 40.37 33.8 - 47.2 1.26 0.61
>128 75.38 63.1 - 85.2 41.28 34.7 - 48.1 1.28 0.60
>129 73.85 61.5 - 84.0 43.12 36.4 - 50.0 1.30 0.61
>130 73.85 61.5 - 84.0 44.95 38.2 - 51.8 1.34 0.58
>131 70.77 58.2 - 81.4 45.87 39.1 - 52.7 1.31 0.64
>132 67.69 54.9 - 78.8 48.17 41.4 - 55.0 1.31 0.67
>133 66.15 53.4 - 77.4 49.54 42.7 - 56.4 1.31 0.68
>134 63.08 50.2 - 74.7 50.92 44.1 - 57.7 1.29 0.73
>135 58.46 45.6 - 70.6 52.29 45.4 - 59.1 1.23 0.79
>136 56.92 44.0 - 69.2 53.21 46.4 - 60.0 1.22 0.81
>137 56.92 44.0 - 69.2 53.67 46.8 - 60.4 1.23 0.80
>138 53.85 41.0 - 66.3 53.67 46.8 - 60.4 1.16 0.86
>139 52.31 39.5 - 64.9 54.13 47.3 - 60.9 1.14 0.88
>142 52.31 39.5 - 64.9 56.88 50.0 - 63.6 1.21 0.84
>143 50.77 38.1 - 63.4 58.26 51.4 - 64.9 1.22 0.85
>144 47.69 35.1 - 60.5 59.63 52.8 - 66.2 1.18 0.88
>146 43.08 30.8 - 56.0 61.47 54.7 - 68.0 1.12 0.93
>147 41.54 29.4 - 54.4 61.93 55.1 - 68.4 1.09 0.94
>148 40.00 28.0 - 52.9 62.39 55.6 - 68.8 1.06 0.96
>153 40.00 28.0 - 52.9 68.81 62.2 - 74.9 1.28 0.87
>154 35.38 23.9 - 48.2 71.10 64.6 - 77.0 1.22 0.91
>157 35.38 23.9 - 48.2 73.85 67.5 - 79.6 1.35 0.87
>158 32.31 21.2 - 45.1 74.31 68.0 - 80.0 1.26 0.91
>159 29.23 18.6 - 41.8 75.69 69.4 - 81.2 1.20 0.94
>160 26.15 16.0 - 38.5 75.69 69.4 - 81.2 1.08 0.98
>161 24.62 14.8 - 36.9 76.15 69.9 - 81.6 1.03 0.99
>163 24.62 14.8 - 36.9 78.44 72.4 - 83.7 1.14 0.96
>164 23.08 13.5 - 35.2 79.82 73.9 - 84.9 1.14 0.96
>165 21.54 12.3 - 33.5 80.73 74.9 - 85.7 1.12 0.97
>166 20.00 11.1 - 31.8 81.19 75.4 - 86.2 1.06 0.99
>169 20.00 11.1 - 31.8 83.49 77.9 - 88.2 1.21 0.96
>171 16.92 8.8 - 28.3 83.49 77.9 - 88.2 1.02 1.00
>174 16.92 8.8 - 28.3 84.40 78.9 - 89.0 1.09 0.98
>176 13.85 6.5 - 24.7 84.40 78.9 - 89.0 0.89 1.02
>181 13.85 6.5 - 24.7 88.99 84.1 - 92.8 1.26 0.97
>182 10.77 4.4 - 20.9 89.91 85.1 - 93.6 1.07 0.99
>183 10.77 4.4 - 20.9 90.37 85.7 - 93.9 1.12 0.99
>184 9.23 3.5 - 19.0 91.28 86.7 - 94.7 1.06 0.99
>186 7.69 2.5 - 17.0 91.28 86.7 - 94.7 0.88 1.01
>187 7.69 2.5 - 17.0 92.20 87.8 - 95.4 0.99 1.00
>189 6.15 1.7 - 15.0 92.20 87.8 - 95.4 0.79 1.02
>190 4.62 1.0 - 12.9 93.12 88.9 - 96.1 0.67 1.02
>202 4.62 1.0 - 12.9 95.41 91.7 - 97.8 1.01 1.00
>204 3.08 0.4 - 10.7 95.41 91.7 - 97.8 0.67 1.02
>208 3.08 0.4 - 10.7 96.79 93.5 - 98.7 0.96 1.00
>210 1.54 0.04 - 8.3 96.79 93.5 - 98.7 0.48 1.02
>214 1.54 0.04 - 8.3 97.25 94.1 - 99.0 0.56 1.01
>217 0.00 0.0 - 5.5 97.25 94.1 - 99.0 0.00 1.03
>303 0.00 0.0 - 5.5 100.00 98.3 - 100.0 1.00

Variable HDL
Classification variable GDS
Sample size 283
Positive group : GDS = 1 65
Negative group : GDS = 0 218

Disease prevalence (%) unknown


Area under the ROC curve (AUC)

Area under the ROC curve (AUC) 0.511


Standard Errora 0.0398
95% Confidence intervalb 0.451 to 0.571
z statistic 0.276
Significance level P (Area=0.5) 0.7827
a
DeLong et al., 1988
b
Binomial exact

Youden index

Youden index J 0.09174


Associated criterion >29
Criterion values and coordinates of the ROC curve [Hide]

Criterion Sensitivity 95% CI Specificity 95% CI +LR -LR


≥21 100.00 94.5 - 100.0 0.00 0.0 - 1.7 1.00
>29 100.00 94.5 - 100.0 9.17 5.7 - 13.8 1.10 0.00
>30 95.38 87.1 - 99.0 11.93 7.9 - 17.0 1.08 0.39
>31 92.31 83.0 - 97.5 15.60 11.0 - 21.1 1.09 0.49
>32 84.62 73.5 - 92.4 18.35 13.4 - 24.1 1.04 0.84
>33 70.77 58.2 - 81.4 23.85 18.4 - 30.1 0.93 1.23
>34 69.23 56.6 - 80.1 26.15 20.4 - 32.5 0.94 1.18
>35 63.08 50.2 - 74.7 33.49 27.3 - 40.2 0.95 1.10
>36 60.00 47.1 - 72.0 44.95 38.2 - 51.8 1.09 0.89
>37 52.31 39.5 - 64.9 51.38 44.5 - 58.2 1.08 0.93
>38 49.23 36.6 - 61.9 57.80 50.9 - 64.4 1.17 0.88
>39 41.54 29.4 - 54.4 61.47 54.7 - 68.0 1.08 0.95
>40 32.31 21.2 - 45.1 66.97 60.3 - 73.2 0.98 1.01
>41 27.69 17.3 - 40.2 72.02 65.6 - 77.9 0.99 1.00
>42 21.54 12.3 - 33.5 78.90 72.9 - 84.1 1.02 0.99
>43 16.92 8.8 - 28.3 82.11 76.4 - 87.0 0.95 1.01
>44 15.38 7.6 - 26.5 85.78 80.4 - 90.1 1.08 0.99
>45 7.69 2.5 - 17.0 87.61 82.5 - 91.7 0.62 1.05
>46 7.69 2.5 - 17.0 88.53 83.5 - 92.4 0.67 1.04
>47 4.62 1.0 - 12.9 88.99 84.1 - 92.8 0.42 1.07
>49 4.62 1.0 - 12.9 89.91 85.1 - 93.6 0.46 1.06
>50 3.08 0.4 - 10.7 91.28 86.7 - 94.7 0.35 1.06
>65 3.08 0.4 - 10.7 94.04 90.0 - 96.8 0.52 1.03
>66 1.54 0.04 - 8.3 94.50 90.6 - 97.1 0.28 1.04
>140 1.54 0.04 - 8.3 99.54 97.5 - 100.0 3.35 0.99
>141 0.00 0.0 - 5.5 99.54 97.5 - 100.0 0.00 1.00
>196 0.00 0.0 - 5.5 100.00 98.3 - 100.0 1.00
Variable LDL
Classification variable GDS

Sample size 283


Positive group : GDS = 1 65
Negative group : GDS = 0 218

Disease prevalence (%) unknown


Area under the ROC curve (AUC)

Area under the ROC curve (AUC) 0.567


Standard Errora 0.0383
95% Confidence intervalb 0.507 to 0.626
z statistic 1.752
Significance level P (Area=0.5) 0.0798
a
DeLong et al., 1988
b
Binomial exact

Youden index

Youden index J 0.2247


Associated criterion >130
Criterion values and coordinates of the ROC curve [Hide]

Criterion Sensitivity 95% CI Specificity 95% CI +LR -LR


≥37 100.00 94.5 - 100.0 0.00 0.0 - 1.7 1.00
>77 100.00 94.5 - 100.0 5.05 2.5 - 8.8 1.05 0.00
>78 98.46 91.7 - 100.0 5.05 2.5 - 8.8 1.04 0.30
>87 98.46 91.7 - 100.0 9.17 5.7 - 13.8 1.08 0.17
>89 95.38 87.1 - 99.0 9.63 6.1 - 14.3 1.06 0.48
>90 95.38 87.1 - 99.0 10.09 6.4 - 14.9 1.06 0.46
>91 93.85 85.0 - 98.3 12.39 8.3 - 17.5 1.07 0.50
>92 93.85 85.0 - 98.3 12.84 8.7 - 18.0 1.08 0.48
>93 92.31 83.0 - 97.5 13.30 9.1 - 18.5 1.06 0.58
>94 92.31 83.0 - 97.5 13.76 9.5 - 19.1 1.07 0.56
>96 89.23 79.1 - 95.6 13.76 9.5 - 19.1 1.03 0.78
>101 89.23 79.1 - 95.6 16.97 12.2 - 22.6 1.07 0.63
>102 87.69 77.2 - 94.5 17.89 13.0 - 23.6 1.07 0.69
>104 86.15 75.3 - 93.5 18.35 13.4 - 24.1 1.06 0.75
>105 84.62 73.5 - 92.4 18.35 13.4 - 24.1 1.04 0.84
>107 84.62 73.5 - 92.4 20.18 15.1 - 26.1 1.06 0.76
>108 83.08 71.7 - 91.2 21.10 15.9 - 27.1 1.05 0.80
>110 83.08 71.7 - 91.2 23.39 17.9 - 29.6 1.08 0.72
>111 81.54 70.0 - 90.1 24.77 19.2 - 31.1 1.08 0.75
>115 81.54 70.0 - 90.1 27.98 22.1 - 34.4 1.13 0.66
>116 80.00 68.2 - 88.9 28.44 22.6 - 34.9 1.12 0.70
>117 80.00 68.2 - 88.9 31.19 25.1 - 37.8 1.16 0.64
>118 78.46 66.5 - 87.7 31.65 25.5 - 38.3 1.15 0.68
>119 78.46 66.5 - 87.7 33.94 27.7 - 40.6 1.19 0.63
>121 75.38 63.1 - 85.2 34.86 28.6 - 41.6 1.16 0.71
>122 73.85 61.5 - 84.0 35.78 29.4 - 42.5 1.15 0.73
>130 73.85 61.5 - 84.0 48.62 41.8 - 55.5 1.44 0.54
>131 72.31 59.8 - 82.7 49.08 42.3 - 55.9 1.42 0.56
>132 70.77 58.2 - 81.4 49.54 42.7 - 56.4 1.40 0.59
>134 70.77 58.2 - 81.4 50.00 43.2 - 56.8 1.42 0.58
>135 66.15 53.4 - 77.4 52.29 45.4 - 59.1 1.39 0.65
>136 64.62 51.8 - 76.1 53.21 46.4 - 60.0 1.38 0.66
>137 63.08 50.2 - 74.7 53.67 46.8 - 60.4 1.36 0.69
>138 56.92 44.0 - 69.2 54.59 47.7 - 61.3 1.25 0.79
>139 56.92 44.0 - 69.2 56.42 49.6 - 63.1 1.31 0.76
>140 53.85 41.0 - 66.3 57.80 50.9 - 64.4 1.28 0.80
>142 53.85 41.0 - 66.3 59.63 52.8 - 66.2 1.33 0.77
>143 49.23 36.6 - 61.9 61.01 54.2 - 67.5 1.26 0.83
>144 47.69 35.1 - 60.5 61.01 54.2 - 67.5 1.22 0.86
>146 47.69 35.1 - 60.5 64.68 57.9 - 71.0 1.35 0.81
>147 46.15 33.7 - 59.0 66.51 59.8 - 72.7 1.38 0.81
>148 44.62 32.3 - 57.5 66.97 60.3 - 73.2 1.35 0.83
>149 43.08 30.8 - 56.0 67.43 60.8 - 73.6 1.32 0.84
>150 41.54 29.4 - 54.4 68.35 61.7 - 74.5 1.31 0.86
>151 38.46 26.7 - 51.4 69.72 63.2 - 75.7 1.27 0.88
>152 36.92 25.3 - 49.8 70.64 64.1 - 76.6 1.26 0.89
>153 35.38 23.9 - 48.2 72.94 66.5 - 78.7 1.31 0.89
>154 27.69 17.3 - 40.2 74.31 68.0 - 80.0 1.08 0.97
>155 26.15 16.0 - 38.5 74.77 68.5 - 80.4 1.04 0.99
>156 24.62 14.8 - 36.9 75.23 68.9 - 80.8 0.99 1.00
>157 24.62 14.8 - 36.9 76.61 70.4 - 82.1 1.05 0.98
>158 21.54 12.3 - 33.5 77.98 71.9 - 83.3 0.98 1.01
>159 18.46 9.9 - 30.0 78.44 72.4 - 83.7 0.86 1.04
>160 18.46 9.9 - 30.0 79.36 73.4 - 84.5 0.89 1.03
>163 15.38 7.6 - 26.5 79.82 73.9 - 84.9 0.76 1.06
>164 13.85 6.5 - 24.7 81.19 75.4 - 86.2 0.74 1.06
>165 13.85 6.5 - 24.7 83.03 77.4 - 87.8 0.82 1.04
>167 12.31 5.5 - 22.8 83.94 78.4 - 88.6 0.77 1.04
>168 12.31 5.5 - 22.8 85.32 79.9 - 89.7 0.84 1.03
>169 10.77 4.4 - 20.9 86.24 80.9 - 90.5 0.78 1.03
>171 9.23 3.5 - 19.0 86.70 81.5 - 90.9 0.69 1.05
>173 7.69 2.5 - 17.0 87.16 82.0 - 91.3 0.60 1.06
>174 6.15 1.7 - 15.0 87.16 82.0 - 91.3 0.48 1.08
>181 6.15 1.7 - 15.0 88.99 84.1 - 92.8 0.56 1.05
>183 4.62 1.0 - 12.9 90.37 85.7 - 93.9 0.48 1.06
>187 4.62 1.0 - 12.9 91.74 87.3 - 95.0 0.56 1.04
>189 1.54 0.04 - 8.3 91.74 87.3 - 95.0 0.19 1.07
>225 1.54 0.04 - 8.3 99.08 96.7 - 99.9 1.68 0.99
>228 0.00 0.0 - 5.5 99.08 96.7 - 99.9 0.00 1.01
>348 0.00 0.0 - 5.5 100.00 98.3 - 100.0 1.00

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