Manaku Honey, the Potential Cartilage Repair

Functional Food
By Kyle J. Norton

Scientists may have found a golden liquid for the treatment of cartilage damage
without inducing any side effects, some studies suggested.

Cartilage is an important structural component placed in the joints of bone with

a function to prevent the end of the bone collided from one to another.

Cartilage is a firm tissue but is softer and much more flexible than bone.

Due to the lack of blood vessels connected to the cartilage to supply the
chondrocytes with nutrients, repairing the damage of cartilage are more slowly
than other tissues.

Cartilage repair is an act is to restore the surface of an joint cartilage. However,

how sufficiency of the works is totally depending on the degree of the damage.

In conventional medicine, cartilage damage due to a single injury, or lesion

can be repaired successfully. However, with many lesions in one joint, are less
likely to benefit from the surgery. cartilage, particularly in older population.

In the article "Articular Cartilage Restoration", the American Academy of

Orthopaedic Surgeons wrote, "Many procedures to restore articular cartilage
are done arthroscopically" and "Some procedures require the surgeon to have
more direct access to the affected area. Longer, open incisions are required.
Sometimes it is necessary to address other problems in the joint, such as
meniscal or ligament tears when cartilage surgery is done"

Honey is the miraculous product made by bees using nectar from flowers.

The rich golden liquid It is considered one of healthy sweet food for replacing
the use of white sugar and artificial sweetener by many people.

With an aim to find the natural ingredient or whole food for the cartilage repair
in replacement of that conventional medicine with no side effects, researchers
at a number of institutes conducted a joint study to evaluate the nature-derived
hydrogels, a promising class of scaffolds for cartilage tissue engineering,
mimicking the native cellular microenvironment.

Manuka honey made hydrogels able to inhibit the proliferation of S. aureus and
S. epidermidis clinical isolates and no cytotoxic effects were detected on
human mesenchymal stem cells seeded on the hydrogels.

Manuka honey initiated a consistent expression of collagen II and high

synthesis of
Sulfated glycosaminoglycans (GAGs) and proteoglycans, thus indicating the
formation of the cartilage matrix.

Where Sulfated glycosaminoglycans and proteoglycans are considered

promising artificial extracellular matrix components to improve the
regeneration of tissues, such as cartilage repair.

These results suggested Manuka honey processes a similar action as those of

synthetic substances used for the treatment to improve cartilage regeneration.

In order to understand the effect of Manuka honey in cartilage repair,

researcher launched a differentiation of the research paper "Antibacterial
effectiveness meets improved mechanical properties: Manuka Honey/Gellan
Gum composite hydrogels for cartilage repair", Bonifacio et al.

And suggested that before Manuka honey can be used for the treatment of
cartilage repair, there are some criteria must be met. you can view them at the
sources

Due to the limitation of the study, therefore, further data collection large
example size and multi-centers studies performed with human consumption of
the whole food during the course of the disease will be necessary to complete
the picture of Manuka honey cartilage repair possibilities.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers
have been written and published online, including worldwide health, ezine
articles, article base, health blogs, self-growth, best before it's news, the karate
GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ
by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington
Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as
international journal Pharma ISSN 0975-6299.

(1) Antibacterial effectiveness meets improved mechanical properties: Manuka

honey/gellan gum composite hydrogels for cartilage repair by Bonifacio MA1,
Cometa S2, Cochis A3, Gentile P4, Ferreira AM5, Azzimonti B6, Procino G7,
Ceci E8, Rimondini L9, De Giglio E10. (PubMed)
(2) Data on Manuka Honey/Gellan Gum composite hydrogels for cartilage
repair by Bonifacio MA1, Cometa S2, Cochis A3, Gentile P4, Ferreira AM4,
Azzimonti B3,5, Procino G6, Ceci E7, Rimondini L3,5, De Giglio E1.
(PubMed)