Beruflich Dokumente
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1. Discuss how AIS use the immune system as metaphor. Consider the pattern
recognition, memory, learning capability and anomaly in your answer.
Artificial Immune Systems (AIS) include algorithms and systems that use the human
immune system as inspiration. The human immune system is a robust, decentralised,
error tolerant and adaptive system. Such properties are highly desirable for the
development of novel computer systems. It also can characterize complex systems
and contribute to the growth of complexity science. The main features of the AIS
include pattern recognition, anomaly, learning capability, memory, and its distributive
nature gives rich metaphors for its artificial counterpart.
SOLUTION
ALGORITHM
AFFINITY
REPRESENTATION
APPLICATION
AFFINITY
Computationally, the degree of interaction of an antibody-antigen or antibody-
antibody can be evaluated by a distance or affinity measure.
REPRESENTATION
Representation affects affinity measure.
Shape space (binary, integer, real-valued, symbolic)
used for modelling antibody and antigen
determine a measure to calculate affinity
ALGORITHM
Bone Marrow Model
Clonal Selection
Negative Selection
Network Models
APPLICATION
Robotics
Behaviour Arbitration
Collective Behaviour
3. Briefly explain how negative selection algorithm diagnose the cancer disease. You
can refer to article/youtube.
Negative selection is a mechanism that protects the body against the autoreactive
lymphocytes. It uses the ability of the immune system to detect unknown antigens
without affecting the self cells. There are two processes which are the recognition of
the shape of the antigen and selecting the antibody specific to it. The idea is that only
antibodies capable of recognizing the antigen are activated for proliferation (cloning
+ mutation).