Beruflich Dokumente
Kultur Dokumente
Chris Griggy
Simon Moattar
Izzy Cozier
Today’s Reflection:
Today, we were able to look up possible diseases. We settled on Type 2 Diabetes and came up
with tasks
● Type 2 Diabetes is a chronic condition that affects the way your body metabolizes sugar.
● It affects the heart, blood vessels, nerves, eyes, and kidneys.
● Diabetes is a problem with your body that causes blood glucose (sugar) levels to rise
higher than normal
● Type 2 diabetes affects the way the body processes blood sugar.
● Type 2 diabetes is characterized by excessive sugar (glucose) in the blood due
to the development of resistance to insulin
● Diabetes is a problem with your body that causes blood glucose (sugar) levels to rise
higher than normal
● People are more likely to develop type 2 diabetes due to genetics or eating habits/weight
problems.
● Signs of Diabetes: Increased thirst and frequent urination, increased hunger, weight
loss, fatigue, blurred vision slow-healing sores or frequent infections, areas of darkened
skin.
● Your risk of type 2 diabetes typically increases when you are:
● Older
● Less active
● Overweight or obese
● Some common treatments of type 2 diabetes are regular exercise, healthy eating, blood
sugar monitoring, or diabetes medication/treatment.
● Other risk factors are:
● Family history of diabetes in close relatives
● Being of African, Asian, Native American, Latino, or Pacific Islander ancestry
● High blood levels of fats, known as triglycerides, coupled with low levels of
● In women, a history of giving birth to large babies (over 9 lbs) and/or diabetes during
pregnancy
● Common side effects: frequent urination, blurred vision, or poor wound healing
● If type 2 diabetes goes untreated, the high blood sugar can affect various cells and
organs in the body
● Complications include kidney damage, often leading to dialysis, eye damage, which
could result in blindness, or an increased risk for heart disease or stroke
● Type 2 diabetes is 90-95% diabetics in America
● In the past 20 years the number of adults with diabetes has tripled.
What is it? Itś a disease that changes the way that the body uses insulin resulting in high blood
sugar levels.
What part of the body does it affect? It affects the way the pancreas produces insulin. High
blood sugar can cause, kidney damage, eye damage, or an increased risk of heart disease or
stroke.
Who is likely to get it? People with family history of diabetes. High blood pressure, high blood
fat levels, pre-diabetes, or common side effects(frequent urination, blurred vision, or poor wound
healing). People who live a sedentary lifestyle are more likely to be affected by diabetes.
What are the treatments? Cure? Treatments include, regular exercise, healthy eating, blood
sugar monitoring and insulin medication.
What are the barriers to curing it? Diabetes can be managed to a point where the body shows no
symptoms but it cannot go away/be cured.
Any interesting research going on? Many foundations are trying to find a cure but none of them
are close. Some new findings may point to stress leading to diabetes in older people, there has
also been very recent developments that will help speed up the treatment and developments of
diabetes.
Protein synthesis:
Sequence:
dna:
mrna+trna
C A A A T G C C C C G C A G C C C A T T T
G U U U A C G G G G C G U C G G G U A A A
http://www.diabetes.org/diabetes-basics/type-2/
https://www.mayoclinic.org/diseases-conditions/type-2-diabetes/symptoms-causes/syc-2035119
3
https://invisiverse.wonderhowto.com/news/defective-infectious-proteins-linked-type-2-diabetes-0
179122/
https://www.niddk.nih.gov/health-information/diabetes/overview/risk-factors-type-2-diabetes
https://www.mayoclinic.org/diseases-conditions/type-2-diabetes/diagnosis-treatment/drc-203511
99
https://www.cdc.gov/diabetes/statistics/slides/maps_diabetes_trends.pdf
End product:
You will give an explanation in any way you choose besides slides to show your
understanding of the disease, the protein and the synthesis of proteins.
● What are the treatments? Cure? End with a 3D model of the protein
f. Ribosomes composed of
rRNA
B. Translation
a. tRNA (transfer RNA) found
in the cytoplasm carry an
amino acid which makes
up protein
b. mRNA dictates what
amino acids from tRNA
are utilized
c. tRNA attaches to
complementary bases on
mRNA
d. Reads bases in triplets
(codons)
e. Different codons apply to
A. Transcription different amino acids
a. Takes place in the nucleus f. Amino acids link together
b. DNA is decoded into in a peptide bond
mRNA C. Folding
c. RNA polymerase (an a. Folding give the protein
enzyme) connects shape and the ability to
complementary RNA actually function
bases to the DNA b. There are 4 parts
d. RNA bases create mRNA i. Primary
e. mRNA leaves nucleus, ii. Secondary
goes to cytoplasm and iii. Tertiary
travels to a ribosome iv. Quaternary
c. Primary
i. Just the chain of ii. Because type 2
amino acids in diabetes has a
cytoplasm problem with insulin
d. Secondary being secreted from
i. Begins to fold in the the pancreas, this is
rough ER where the problem
ii. Forms the takes place
secondary DNA
structures of a helix G T T T A C G G G G C G T C G G G T A A
A
and b sheets
C A A A T G C C C C G C A G C C C A T T
e. Tertiary T
mRNA:
i. More folding takes
C A A A T G C C C C G C A G C C C A T T
place, based on the T
hydrophobic and mRNA+tRNA
C A A A T G C C C C G C A G C C C A T T
hydrophilic parts of T
the protein G U U U A C G G G G C G U C G G G U A A
A
ii. Takes place in ER Amino Acids:
and golgi Valine, tyrosine, valine, alanine, serine,
glycine, lysine
f. Quaternary
i. From golgi,
transferred where
needed
Hold up, let me get it started
‘Betes with the sugar, lookin' disregarded
Insulin saggin', pancreas lackin
This ain’t a trick 'cause my blood sugar trashin