Beruflich Dokumente
Kultur Dokumente
Contents
Experimental Studies
Poor Memory Performance in Aged Cynomolgus Monkeys with Hippocampal Atrophy, Depletion of
Amyloid Beta 1-42 and Accumulation of Tau Proteins in Cerebrospinal Fluid. H. S. DARUSMAN, J.
PANDELAKI, R. MULYADI, D. SAJUTHI, I. A. PUTRI, O. H. KALLIOKOSKI, J. CALL, K. S. P.
ABELSON, S. J. SCHAPIRO, A. GJEDDE, J. HAU (Copenhagen; Aarhus, Denmark; Jakarta; Bogor,
Indonesia; Leipzig, Germany; Bastrop, TX; Baltimore, MD, U.S.A.; Montréal, QC, Canada) ............... 173
Circulating Human Fractalkine is Decreased Post-operatively After Orthopedic and Coronary Bypass
Surgery. T. ÅKERFELDT, J. HELMERSSON-KARLQVIST, T. GORDH, A. LARSSON (Uppsala,
Sweden).................................................................................................................................................. 185
Effects of Mouse Genotype on Bone Wound Healing and Irradiation-induced Delay of Healing. J.
GLOWACKI, S. MIZUNO, J. KUNG, J. GOFF, M. EPPERLY, T. DIXON, H. WANG, J. S.
GREENBERGER (Boston, MA; Pittsburgh, PA, U.S.A.) ........................................................................ 189
The Effect of Dietary Oils on the Development of Aberrant Crypt Foci, Bifidobacteria and Fecal pH.
F. DA SILVA FRANÇA, C. BODACK, A. COSTA, F. C. DESCHAMPS, F. MARTINELLO
(Florianόpolis; Itajaί, Santa Catarina, Brazil) ......................................................................................... 197
p66shc and Gender-specific Dimorphism in Acute Renal Injury. D. K. REED, I. ARANY (Jackson, MS,
U.S.A.) .................................................................................................................................................... 205
Contents continued on the back cover
International Journal of Experimental and Clinical Pathophysiology and Drug Research
ISSN (print): 0258-851X, ISSN (online): 1791-7549
Supported by:
The International Institute of Anticancer Research IIAR
Dates and Venue Special sessions will be devoted to the discussion and arrangement of
international cooperation projects and activities, encompassing the
The 9th International Conference of Anticancer Research will aims of the International Institute of Anticancer Research.
be held at the Porto Carras Grand Resort, Sithonia, Halkidiki, The Conference is organized and supported by the International
Greece, from 6 to 10 October, 2014. Institute of Anticancer Research.
The Scientific Program will comprise of oral (10, 15, 30 or 40
General Policy minutes) and poster presentations. Both overviews and original works
The purpose of the Anticancer Research Conferences is to exchange will be presented. Each oral presentation will be allocated a five-
scientific information worldwide and to discuss recent advances in minute discussion-time. Six conference rooms will be used
both broad and specialized areas of experimental and clinical cancer simultaneously. Posters will be exhibited for 1-2 days. Projection
research. International Scientific and Medical Societies are invited to facilities for PowerPoint presentations will be provided.
participate in the Conference by organizing specialized sessions. This The Conference website (www.iiar-anticancer.org/conference) will
initiative presents a forum for inter-Society communication allowing be consistently updated announcing new titles of accepted abstracts,
the organization and coordination of international activities on cancer. new special symposia and social events.
Organizing Committee
P.A. Abrahamsson, Malmö, Sweden J.W. Greiner, Bethesda, MD, USA J. Reichrath, Homburg/Saar, Germany
N. Agnantis, Ioannina, Greece F. Guadagni, Rome, Italy D.A. Ribeiro, Santos, SP, Brazil
F.E. Ahmed, Greenville, NC, USA C. Hastie, Guildford, Surrey, UK M. Rigaud, Limoges, France
C. Alexiou, Erlangen, Germany J. Hau, Copenhagen, Denmark F.M. Robertson, Houston, TX, USA
L. Amaral, Lisbon, Portugal R. Hoffman, San Diego, CA, USA M. Roselli, Rome, Italy
F.L. Ampil, Shreveport, LA, USA S. Holdenrieder, Bonn, Germany G.R. Rutteman, Utrecht, Netherlands
R. Andersson, Lund, Sweden T. Isbir, Istanbul, Turkey C. Sansom, London, UK
S. Arbak, Istanbul, Turkey S. Jhanwar, New York, NY, USA S. Sarkar, Boston, MA, USA
V. Barak, Jerusalem, Israel M. Jhanwar-Uniyal, New York, NY, USA A. Schauer, Göttingen, Germany
D.-T. Bau, Taichung, Taiwan B. Kaina, Mainz, Germany D. Schiffer, Vercelli, Italy
G. Bauer, Freiburg, Germany E. Kandil, New Orleans, LA, USA J. Schneider, Alcorcón (Madrid) Spain
A. Bishayee, Signal Hill, CA, USA D.G. Kieback, Riesa (Dresden), Germany M. Schneider, Wuppertal, Germany
R. Bjerkvig, Bergen, Norway I. Kiss, Pécs, Hungary O.J. Semmes, Norfolk, VA, USA
G. Broich, Monza, Italy R. Klapdor, Hamburg, Germany A. Seth, Toronto, ON, Canada
C. Carlberg, Kuopio, Finland R. Knecht, Hamburg, Germany G. Sica, Rome, Italy
J. Carlsson, Uppsala, Sweden M. Kohonen-Corish, Sydney, NSW, J. Slansky, Denver, CO, USA
D. Characiejus, Vilnius, Lithuania Australia K. Smetana, Prague, Czech Republic
C.J. Chen, Taipei, Taiwan M. Koutsilieris, Athens, Greece S.S. Smith, Duarte, CA, USA
G. Ciarimboli, Münster, Germany K. Kubota, Mibu, Tochigi, Japan R.M. Snapka, Columbus, OH, USA
B.F.C. Clark, Aarhus, Denmark S. Kumar, Manchester, UK J. Sterling, Nashville, TN, USA
R. Clarke, Washington, DC, USA P.M. Kumar, Manchester, UK T. Stigbrand, Umeå, Sweden
P. Collery, Bastia, France O.D. Laerum, Bergen, Norway K. Syrjänen, Helsinki, Finland
H. Cross, Vienna, Austria S.A. Lamprecht, Beer-Sheva, Israel R.T. Todorova, Sofia, Bulgaria
M. De Braekeleer, Brest, France W. Lichtenegger, Berlin, Germany O. Topolcan, Pilsen, Czech Republic
K. De Meirleir, Brussels, Belgium D. Lincoln, Chapel Hill, QLD, Australia G.C. Torre, Finale Ligure (SV), Italy
A.Z. Dudek, Chicago, IL, USA B. Littlefield, Andover, MA, USA V. Treska, Pilsen, Czech Republic
A. Dutour, Lyon, France F. Lumachi, Padova, Italy M. de L.G. Trigo, Porto, Portugal
P. Dziegiel, Wroclaw, Poland S. Mitra, Galveston, TX, USA G. Tsangaris, Athens, Greece
T. Efferth, Mainz, Germany R. Molina, Barcelona, Spain E. Vairaktaris, Athens, Greece
W. Engström, Uppsala, Sweden J. Molnár, Szeged, Hungary D. Vesely, Tampa, FL, USA
M. Eskelinen, Kuopio, Finland N. Motohashi, Tokyo, Japan D. Vetvicka, Prague, Czech Republic
J.A. Fernandez-Pol, Chesterfield, MO, USA R.M. Nagler, Haifa, Israel J.K. Vishwanatha, Fort Worth, TX, USA
A. Fields, Jacksonville, FL, USA N. Nguyen, Tucson, AZ, USA G. Vollmer, Dresden, Germany
M. Friedrich, Krefeld, Germany C. Nicolini, Genova, Italy A. Wani, Columbus, OH, USA
R. Friedrich, Hamburg, Germany C. Pace-Asciak, Toronto, ON, Canada I.P. Witz, Tel Aviv, Israel
H.-J. Gabius, Munich, Germany S. Pathak, Houston, TX, USA Y. Yen, Duarte, CA, USA
R. Ganapathi, Charlotte, NC, USA G.J. Pilkington, Portsmouth, UK C.H. Yip, Petaling Jaya, Malaysia
A.F. Gazdar, Dallas, TX, USA C.D. Platsoucas, Norfolk, VA, USA O. Zoras, Heraklion, Greece
V. Gebbia, Palermo, Italy A. Polliack, Jerusalem, Israel
Scientific Program
Experimental Research Sessions 16. Apoptosis. 31. Radiotherapy.
1. Oncogenes; tumor suppressor genes; 17. Tumor microenvironment; cell–cell 32. Hyperthermia.
growth factors; signal transduction. interactions; adhesion; stroma; cancer- 33. Personalized medicine in cancer.
2. Molecular and cellular biology of cancer. associated fibroblasts. 34. Advances in breast cancer.
3. Cancer stem cells. 18. Carcinogenesis. Viral oncogenesis. 35. Advances in gynecological cancer.
4. Cancer cell differentiation. 19. New anticancer agents. 36. Advances in prostate cancer.
5. Cancer genomics. Microarray technology. 20. Natural products in cancer drug 37. Advances in neurooncology.
6. Cancer proteomics. Metabolomics. development. 38. Advances in colorectal cancer.
7. Cancer systems biology and signaling. 21. Experimental chemotherapy. 39. Advances in head and neck cancer.
8. Cancer metabolism and autophagy. 22. Immunobiology of cancer. 40. Advances in stomach and esophageal
9. Reactive oxygen/nitrogen species and 23. Gene therapy. cancer.
cancer. 24. Aging and cancer. 41. Advances in hemato-oncology.
10. MicroRNAs in cancer. 42. Melanoma: New therapies and
11. Invasion and metastasis. Clinical Research Sessions biomarkers.
12. Cytogenetics and genetics. 25. Diagnosis and prognosis of cancer. 43. Chemoprevention. Enviromental
13. Epigenetics. 26. Cancer surgery. exposure and cancer risk.
14. Tumor angiogenesis and anti- 27. Serum markers in diagnosis and therapy. 44. Epidemiology.
angiogenesis. 28. Clinical chemotherapy. 45. Nutrition and cancer. Nutritional aspects
15. Multi-drug and drug resistance. 29. Immunotherapy; biotherapy; vaccines. of cancer prevention.
Mechanisms and reversal. 30. Hormone therapy.
Special Symposia
1. PKC signaling in cancer. Organized by 8. Image-guided radiotherapy. Organized 17. Vitamin D and Cancer. Organized by
A.P. Fields (Jacksonville, FL, USA) by Nam Nguyen (Tucson, AZ, USA) M. Friedrich (Krefeld, Germany),
2. Hepatocellular carcinoma. Organized by 9. Circulating tumor cells. Organized by J. Reichrath (Homburg/Saar, Germany)
Keichi Kubota (Mibu, Tochigi, Japan) - M. Rigaud (Limoges, France) 18. Biobanks: A research infrastructure for
(Wednesday, 8 October 2014) 10. Cancer stem cells. Organized by the future of translational and clinical
3. Cancer Prevention in Asia Pacific M. Jhanwar-Uniyal (New York, NY, research. Organized by F. Guadagni
Countries. Organized by C.H. Yip USA), F. Guadagni (Rome, Italy) (Rome, Italy), M. Roselli (Rome, Italy)
(Petaling Jaya, Malaysia), C.J. Chen 11. Regulation of efflux pumps of mdr cancer 19. New insight into brain tumors. Organized
(Taipei, Taiwan) (APOCP) – (Thursday, 9 by phenothiazine derivatives and natural by G. Sica (Rome, Italy), M. Jhanwar-
October 2014) products. Organized by L. Amaral (Lisbon, Uniyal (New York, NY, USA)
4. Invasion and carcinomas of the GI tract. Portugal), J. Molnár (Szeged, Hungary) 20. Micro RNAs in cancer. Organized by
Organized by O.D. Laerum (Bergen, 12. Drug delivery. Organized by D. Vetvicka A. Seth (Toronto, ON, Canada)
Norway) (Prague, Czech Republic) 21. Next generation sequencing for cancer
5. Toxicology and cancer aetiology. 13. Genomics and clinical management of drug development and diagnostics.
Organized by C.H. Yip (Petaling Jaya, ovarian cancer. Organized by R. Ganapathi Organized by A. Seth (Toronto, ON,
Malaysia), C.J. Chen (Taipei, Taiwan) (Charlotte, NC, USA) Canada)
(APOCP) – (Thursday, 9 October 2014) 14. New insights in prostate cancer. Organized 22. Transporters as mediators of uptake of
6. Genomic instability and cancer (DNA by C. Aukim-Hastie (Guildford, Surrey, UK) chemotherapeutic drugs in target and non-
repair). Organized by A. Wani (Columbus, 15. Hox genes in cancer. Organized by target cells. Organized by G. Ciarimboli
OH, USA) C. Aukim-Hastie (Guildford, Surrey, UK) (Münster, Germany)
7. Drug resistance in cancer and targeting 16. Application of RT-qPCR in Biomedicine. 23. Metal-based drugs and cancer.
DNA repair pathways. Organized by Organized by F.E. Ahmed (Greenville, Organized by P. Collery (Bastia,
S. Mitra (Galveston, TX, USA) NC, USA) France)
Publications Accommodation
Abstracts of all contributed papers will be published in a special issue Hotel reservation requests should be submitted directly to the
of ANTICANCER RESEARCH, which will be distributed to Editorial Office of Anticancer Research. Porto Carras Grand Resort
registrants during the Conference, as well as to all subscribing (HHHHH) is located in a beautiful, peaceful setting by the sea and
libraries and indexing services (print and online through the Stanford will provide excellent service and quality half-board accommodation
University HighWire Press). After recommendation by the Organizing for all participants.
Committee, selected contributions will be invited as complete original l Accommodation fees:
papers or reviews to be submitted for publication in ANTICANCER – Double room: EURO 132.00 for 2 persons, per night.
RESEARCH. Paper submissions will also be welcome during the – Single room: EURO 98.00 per person, per night.
Conference. – Children 2-12 years old as 3rd person in double room: EURO
Abstracts (titles and authors) will be announced in www.iiar- 35.00.
anticancer.org/conference upon acceptance. The final conference – Triple room: EURO 180.00 for 3 persons, per night.
program will be publicised on September 10, 2014. The fee covers: accommodation in A (HHHHH) type rooms (bath,
balcony, radio, TV, telephone), breakfast, dinner and transportation
from and to the Airport of Thessaloniki on October 5 and October
Registration 11, 2014, respectively.
– Registration is required of all participants. l Service hours: Breakfast (buffet): 7.30 – 10.00 a.m.; Dinner
– Registration deadline: 26 September, 2014. (formal club style) 19.00 – 22.30 p.m.; Self-service restaurant for
– Deadline for submission of abstracts: 10 August, 2014. lunch: 12.30 – 14.00 p.m.
– Registration fee: EURO 260.00; Students, EURO 100.00; l Accommodation requests are valid if made through the official
accompanying person, EURO 100.00 (each); Children, no fee. conference Registration Form. For accommodation & registration
– The registration fee for the Conference participants partially covers: to be secured all fees need to have been paid in advance.
attendance at the scientific sessions; all Conference material and l Cancellations: Abstract and registration plus accommodation fees
documentation (final program, list of participants, book of will be returned if participation is cancelled before August 10,
Abstracts, Conference folder, Certificate of attendance and 2014. No refunds will be offered past this date.
registration badge) from the Conference Secretariat; participation
in all social events (social dinners, music recital, coffee breaks, Travel Arrangements
closing gala dinner), and conference gifts.
The Conference will officially commence on the morning of October 6,
– The registration fee for accompanying persons covers: participation 2014. Therefore, participants should preferably arrive on October 5,
in all social events; eligibility for special accommodation fees (the 2014. The conference will conclude with the closing gala dinner on
same offer applies to Conference participants). October 10, 2014. Participants are advised to finalize their travel plans
– The registration fee for the Members of the auspicious societies is at the earliest possible date. Details of date, flight number and time of
waived. arrival at Thessaloniki Airport should be given to the Editorial Office
– Registration will be regarded as final only after all forms and not later than September 26, 2014.
registration plus accommodation fees have been received by the Aegean Airlines: www.aegeanair.com
Editorial Office of Anticancer Research. Olympic Airways: www.olympicairlines.com
Airport – Hotel Transportation Social Program
Shuttle buses will provide transportation from Thessaloniki l Opera Evening.
Airport to the Hotel only on Sunday, October 5, 2014, and from DIMITRA THEODOSSIOU, soprano.
the Hotel to the airport only on Saturday, October 11, 2014. DIMITRIS YAKAS, piano.
Participants will be welcomed at the airport by a conference Arias by Verdi, Puccini, Mascagni.
representative. Participants arriving on days other than October No fee (date to be announced).
5 or departing on days other than October 11 will have to hire
l Classical Guitar Recital. No fee (date to be announced).
a taxi (50 min, Euro ~120) at their own expense.
l Greek songs recital. No fee (date to be announced).
l Greek traditional dances. No fee (date to be announced).
Instructions for Submitting an Abstract
l Closing ceremony and Gala Dinner on Friday, October 10,
1. Only abstracts containing new results (original research work 2014. No fee.
or overviews) will be accepted. Abstracts should clearly and
l A special program of visits to archaeological sites, visits to museums,
adequately describe the objectives and results of the research.
excursions, and tours will also be available.
All abstracts must be submitted in English.
The program includes: The Holy Monasteries of Mount Athos
2. All abstracts need to be accompanied by a completed (excursion and cruise); Alexander the Great tour (Pella, Vergina,
Conference Registration Form made out in the name of the
Veroia); Dion; Amphipolis, Filippoi, Kavala; Thessaloniki tour,
Author presenting the paper.
Byzantine and Archaelogical Museums, etc. Tickets can be ordered
a. Each abstract should include a title (in capital letters), at the desk of the Conference Secretariat.
names of all authors (with the name of the author who will
be presenting the paper underlined), as well as complete
address(es). Sithonia
b. Two types of abstracts may be submitted:
Sithonia, the central peninsula of Chalkidiki, is varnished with
l Short abstract, not exceeding 300 words. unique, virgin bays and plenty of serene and natural beaches.
l Long abstracts not exceeding 1500 words, with 1-2 The place that hosted both Aristotle and Alexander the Great
figures or tables (max size 8 cm width x 12 cm height), has succeeded in keeping a low profile in mass tourism
including abstract, introduction, materials and methods, campaigns and maintaining its cultural uniqueness and natural
results, discussion, acknowledgements, references. beauty. Situated right next to Thessaloniki, voted best of the
Color figures will be charged 180.00 EURO per page. world places by National Geographic, it dazzles the
c. Careful typing and proof-reading are essential. international traveler with an interminable list of archaeological
d. Abstract forms will not be provided. sights of great magnitude. The museum of Vergina hosts
3. Abstracts and a completed Conference Registration Form immaculate gold treasuries from the burial site of King Philip II,
should be sent to: Dr. John G. Delinasios, International Institute Alexander the Great’s father. The ancient Kavala aqueduct, the
of Anticancer Research, 1st km Kapandritiou-Kalamou Rd, P.O. ancient theatre of Filippoi, the archaelogical areas of Vergina,
Box 22, Kapandriti 19014, Greece. E-mail: conference@iiar- Dion and Pella, and countless byzantine monuments and
anticancer.org. churches are only a few of the nearby sites that inspire a great
historical time travel experience.
Abstracts must arrive at our offices
by August 10, 2014, at the latest.
Weather
4. A reply (regarding decision, acceptance or revision) will reach
October is a very pleasant month in Sithonia, Greece. The
the author within 5-12 days from submission.
average temperature is 24˚C (range 20-30˚C).
Title: ........................................................................................................................................................
Name: ..................................................................................................... Sex: male n or female n
Institution (or Company): ..........................................................................................................................
Address: .................................................................................................................................................
Tel: .......................................... Fax: .......................................... E-mail: ..........................................