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1/5/2019 Dietary fiber - Wikipedia

Dietary fiber
Dietary fiber or roughage is the portion of plant-derived food that
cannot be completely broken down by digestive enzymes.[1] It has two main
components:[2]

Soluble fiber – which dissolves in water – is readily fermented in the


colon into gases and physiologically active by-products, such as short-
chain fatty acids produced in the colon by gut bacteria;[1] it is viscous,
may be called prebiotic fiber, and delays gastric emptying which, in
humans, can result in an extended feeling of fullness.[1]
Insoluble fiber – which does not dissolve in water – is inert to digestive Foods rich in fibers: fruits,
enzymes in the upper gastrointestinal tract and provides bulking.[1] vegetables and grains.
Some forms of insoluble fiber, such as resistant starches, can be
fermented in the colon.[1][3][4] Bulking fibers absorb water as they
move through the digestive system, easing defecation.
Dietary fiber consists of non-starch polysaccharides and other plant
components such as cellulose, resistant starch, resistant dextrins, inulin,
lignins, chitins, pectins, beta-glucans, and oligosaccharides.[1][2]

Dietary fibers can act by changing the nature of the contents of the
gastrointestinal tract and by changing how other nutrients and chemicals
are absorbed.[5] Some types of soluble fiber absorb water to become a
gelatinous, viscous substance which may or may not be fermented by
Wheat bran has a high content of
bacteria in the digestive tract. Some types of insoluble fiber have bulking
dietary fiber.
action and are not fermented.[6] Lignin, a major dietary insoluble fiber
source, may alter the rate and metabolism of soluble fibers.[2] Other types
of insoluble fiber, notably resistant starch, are fermented to produce short-chain fatty acids, which are physiologically
active and confer health benefits.[1][3][4]

Food sources of dietary fiber have traditionally been divided according to whether they provide soluble or insoluble
fiber. Plant foods contain both types of fiber in varying amounts, according to the plant's characteristics of viscosity
and fermentability.[1][7] Advantages of consuming fiber depend upon which type of fiber is consumed and which
benefits may result in the gastrointestinal system.[8] Bulking fibers – such as cellulose, hemicellulose and psyllium –
absorb and hold water, promoting regularity.[9] Viscous fibers – such as beta-glucan and psyllium – thicken the fecal
mass.[9] Fermentable fibers – such as resistant starch and inulin – feed the bacteria and microbiota of the large
intestine, and are metabolized to yield short-chain fatty acids, which have diverse roles in gastrointestinal
health.[10][11]

Contents
Definition
Types and sources of dietary fiber
Fiber contents in food
Plant sources of fiber
Fiber supplements
Inulins
Vegetable gums

Activity in the gut


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Physicochemical properties
Dietary fiber in the upper gastrointestinal tract
Fiber in the colon
Dietary fiber and cholesterol metabolism
Dietary fiber and fecal weight
Effects of fiber intake
Research
Dietary fiber and obesity
Guidelines on fiber intake
Fiber recommendations
United States
United Kingdom

Fiber and fermentation


Short-chain fatty acids
FDA-approved health claims
See also
References

Definition
Dietary fiber is defined to be plant components that are not broken down by human digestive enzymes.[1] In the late
20th century, only lignin and some polysaccharides were known to satisfy this definition, but in the early 21st century,
resistant starch and oligosaccharides were included as dietary fiber components.[1][6]

Official definition of dietary fiber varies among different institutions:

Organization Definition
Institute of Dietary fiber consists of nondigestible carbohydrates and lignin that are intrinsic and intact in
Medicine[12] plants. "Added Fiber" consists of isolated, nondigestible carbohydrates that have beneficial
(2001) physiological effects in humans.

American Dietary fiber is the edible parts of plants or analogous carbohydrates that are resistant to
Association of digestion and absorption in the human small intestine, with complete or partial fermentation in
Cereal the large intestine. Dietary fiber includes polysaccharides, oligosaccharides, lignin, and
Chemists[13] associated plant substances. Dietary fibers promote beneficial physiologic effects including
(2001) laxation, and/or blood cholesterol attenuation, and/or blood glucose attenuation.

Codex
Alimentarius
Commission[14]
(2014; adopted by Dietary fiber means carbohydrate polymers with more than 10 monomeric units, which are not
the European hydrolyzed by digestive enzymes in the small intestine of humans.
Commission and
10 countries
internationally)

Dietary fibre refers to a group of substances in plant foods which cannot be completely broken
British Nutrition down by human digestive enzymes. This includes waxes, lignin and polysaccharides such as
Foundation[1] cellulose and pectin. Originally it was thought that dietary fibre was completely indigestible and
(2018) did not provide any energy. It is now known that some fibre can be fermented in the large
intestine by gut bacteria, producing short chain fatty acids and gases.

Types and sources of dietary fiber

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Food
Nutrient Source/Comments
additive
water-insoluble dietary fibers
β-glucans (a few of which are water-soluble)
Cellulose E 460 cereals, fruit, vegetables (in all plants in general)
Chitin — in fungi, exoskeleton of insects and crustaceans
Hemicellulose cereals, bran, timber, legumes
Hexoses — wheat, barley
Pentose — rye, oat
Lignin — stones of fruits, vegetables (filaments of the garden bean), cereals
Xanthan gum E 415 production with Xanthomonas-bacteria from sugar substrates
Can be starch protected by seed or shell (type RS1), granular starch (type
Resistant starch
RS2) or retrograded starch (type RS3)[3]
high amylose corn, barley, high amylose wheat, legumes, raw bananas,
Resistant starch —
cooked and cooled pasta and potatoes[3]
water-soluble dietary fibers
Arabinoxylan (a
— psyllium[15]
hemicellulose)
replace or complement in some plant taxa the starch as storage
Fructans
carbohydrate
Inulin — in diverse plants, e.g. topinambour, chicory, etc.
Polyuronide
Pectin E 440 in the fruit skin (mainly apples, quinces), vegetables
Alginic acids E 400–
in Algae
(Alginates) E 407
Sodium alginate E 401
Potassium alginate E 402
Ammonium
E 403
alginate
Calcium alginate E 404
Propylene glycol
E 405
alginate (PGA)
agar E 406
carrageen E 407 red algae
Raffinose — legumes
Xylose — monosacharide, pentose
Polydextrose E 1200 synthetic polymer, ca. 1kcal/g
Lactulose — synthetic disaccharide

Fiber contents in food


Dietary fibers are found in fruits, vegetables and whole grains. The amount of fiber contained in common foods are in
the following table:[16]

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Food group Serving mean Fibermass per serving

Fruit 120 mL (0.5 cup)[17][18] 1.1 g

Dark green vegetables 120 mL (0.5 cup) 6.4 g


Orange vegetables 120 mL (0.5 cup) 2.1 g
Cooked dry beans (legumes) 120 mL (0.5 cup) 8.0 g
Starchy vegetables 120 mL (0.5 cup) 1.7 g
Other vegetables 120 mL (0.5 cup) 1.1 g
Whole grains 28 g (1 oz) 2.4 g
Meat 28 g (1 oz) 0.1 g

Dietary fiber is found in plants, typically eaten whole, raw or cooked, although fiber can be added to make dietary
supplements and fiber-rich processed foods. Grain bran products have the highest fiber contents, such as crude corn
bran (79 g per 100 g) and crude wheat bran (43 g per 100 g), which are ingredients for manufactured foods.[16]
Medical authorities, such as the Mayo Clinic, recommend adding fiber-rich products to the Standard American Diet
(SAD) which is rich in processed and artificially sweetened foods, with minimal intake of vegetables and
legumes.[19][20]

Plant sources of fiber


Some plants contain significant amounts of soluble and insoluble fiber. For example, plums and prunes have a thick
skin covering a juicy pulp. The skin is a source of insoluble fiber, whereas soluble fiber is in the pulp. Grapes also
contain a fair amount of fiber.[21]

Soluble fiber is found in varying quantities in all plant foods, including:

legumes (peas, soybeans, lupins and other beans)


oats, rye, chia, and barley
some fruits (including figs, avocados, plums, prunes, berries, ripe bananas, and the skin of apples, quinces and
pears)
certain vegetables such as broccoli, carrots, and Jerusalem artichokes
root tubers and root vegetables such as sweet potatoes and onions (skins of these are sources of insoluble fiber
also)
psyllium seed husks (a mucilage soluble fiber) and flax seeds
nuts, with almonds being the highest in dietary fiber
Sources of insoluble fiber include:

whole grain foods


wheat and corn bran
legumes such as beans and peas
nuts and seeds
potato skins
lignans
vegetables such as green beans, cauliflower, zucchini (courgette), celery, and nopal
some fruits including avocado, and unripe bananas
the skins of some fruits, including kiwifruit, grapes and tomatoes[22]

Fiber supplements

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These are a few example forms of fiber that have been sold as supplements or food additives. These may be marketed
to consumers for nutritional purposes, treatment of various gastrointestinal disorders, and for such possible health
benefits as lowering cholesterol levels, reducing risk of colon cancer, and losing weight.

Soluble fiber supplements may be beneficial for alleviating symptoms of irritable bowel syndrome, such as diarrhea or
constipation and abdominal discomfort.[23] Prebiotic soluble fiber products, like those containing inulin or
oligosaccharides, may contribute to relief from inflammatory bowel disease,[24] as in Crohn's disease,[25] ulcerative
colitis,[26][27] and Clostridium difficile,[28] due in part to the short-chain fatty acids produced with subsequent anti-
inflammatory actions upon the bowel.[29][30] Fiber supplements may be effective in an overall dietary plan for
managing irritable bowel syndrome by modification of food choices.[31]

One insoluble fiber, resistant starch from high-amylose corn, has been used as a supplement and may contribute to
improving insulin sensitivity and glycemic management[32][33][34] as well as promoting regularity[35] and possibly relief
of diarrhea.[36][37][38] One preliminary finding indicates that resistant corn starch may reduce symptoms of ulcerative
colitis.[39]

Inulins
Chemically defined as oligosaccharides occurring naturally in most plants, inulins have nutritional value as
carbohydrates, or more specifically as fructans, a polymer of the natural plant sugar, fructose. Inulin is typically
extracted by manufacturers from enriched plant sources such as chicory roots or Jerusalem artichokes for use in
prepared foods.[40] Subtly sweet, it can be used to replace sugar, fat, and flour, is often used to improve the flow and
mixing qualities of powdered nutritional supplements, and has significant potential health value as a prebiotic
fermentable fiber.[41]

Inulin is advantageous because it contains 25–30% the food energy of sugar or other carbohydrates and 10–15% the
food energy of fat. As a prebiotic fermentable fiber, its metabolism by gut flora yields short-chain fatty acids (see
below) which increase absorption of calcium,[42] magnesium,[43] and iron,[44] resulting from upregulation of mineral-
transporting genes and their membrane transport proteins within the colon wall. Among other potential beneficial
effects noted above, inulin promotes an increase in the mass and health of intestinal Lactobacillus and
Bifidobacterium populations.

Inulin's primary disadvantage is its tolerance. As a soluble fermentable fiber, it is quickly and easily fermented within
the intestinal tract, which may cause gas and digestive distress at doses higher than 15 grams/day in most people.[45]
Individuals with digestive diseases have benefited from removing fructose and inulin from their diet.[46] While clinical
studies have shown changes in the microbiota at lower levels of inulin intake, some of the health effects require higher
than 15 grams per day to achieve the benefits.[47]

Vegetable gums
Vegetable gum fiber supplements are relatively new to the market. Often sold as a powder, vegetable gum fibers
dissolve easily with no aftertaste. In preliminary clinical trials, they have proven effective for the treatment of irritable
bowel syndrome.[48] Examples of vegetable gum fibers are guar gum and gum arabic.

Activity in the gut


Many molecules that are considered to be "dietary fiber" are so because humans lack the necessary enzymes to split
the glycosidic bond and they reach the large intestine. Many foods contain varying types of dietary fibers, all of which
contribute to health in different ways.

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Dietary fibers make three primary contributions: bulking, viscosity and fermentation.[49] Different fibers have
different effects, suggesting that a variety of dietary fibers contribute to overall health. Some fibers contribute through
one primary mechanism. For instance, cellulose and wheat bran provide excellent bulking effects, but are minimally
fermented. Alternatively, many dietary fibers can contribute to health through more than one of these mechanisms.
For instance, psyllium provides bulking as well as viscosity.

Bulking fibers can be soluble (i.e., psyllium) or insoluble (i.e., cellulose and hemicellulose). They absorb water and can
significantly increase stool weight and regularity. Most bulking fibers are not fermented or are minimally fermented
throughout the intestinal tract.[49]

Viscous fibers thicken the contents of the intestinal tract and may attenuate the absorption of sugar, reduce sugar
response after eating, and reduce lipid absorption (notably shown with cholesterol absorption). Their use in food
formulations is often limited to low levels, due to their viscosity and thickening effects. Some viscous fibers may also
be partially or fully fermented within the intestinal tract (guar gum, beta-glucan, glucomannan and pectins), but some
viscous fibers are minimally or not fermented (modified cellulose such as methylcellulose and psyllium).[49]

Fermentable fibers are consumed by the microbiota within the large intestines, mildly increasing fecal bulk and
producing short-chain fatty acids as byproducts with wide-ranging physiological activities (discussion below).
Resistant starch, inulin, fructooligosaccharide and galactooligosaccharide are dietary fibers which are fully fermented.
These include insoluble as well as soluble fibers. This fermentation influences the expression of many genes within the
large intestine,[50] which affect digestive function and lipid and glucose metabolism, as well as the immune system,
inflammation and more.[51]

Dietary fibers can change the nature of the contents of the gastrointestinal tract and can change how other nutrients
and chemicals are absorbed through bulking and viscosity.[2][5] Some types of soluble fibers bind to bile acids in the
small intestine, making them less likely to re-enter the body; this in turn lowers cholesterol levels in the blood from
the actions of cytochrome P450-mediated oxidation of cholesterol.[6]

Insoluble fiber is associated with reduced risk of diabetes, but the mechanism by which this is achieved is unknown.[52]
One type of insoluble dietary fiber, resistant starch, may increase insulin sensitivity in healthy people,[53][54] in type 2
diabetics,[55] and in individuals with insulin resistance, possibly contributing to reduced risk of type 2
diabetes.[56][57][58]

Not yet formally proposed as an essential macronutrient, dietary fiber has importance in the diet, with regulatory
authorities in many developed countries recommending increases in fiber intake.[2][5][59][60]

Physicochemical properties
Dietary fiber has distinct physicochemical properties. Most semi-solid foods, fiber and fat are a combination of gel
matrices which are hydrated or collapsed with microstructural elements, globules, solutions or encapsulating walls.
Fresh fruit and vegetables are cellular materials.[61][62][63]

The cells of cooked potatoes and legumes are gels filled with gelatinized starch granules. The cellular structures
of fruits and vegetables are foams with a closed cell geometry filled with a gel, surrounded by cell walls which are
composites with an amorphous matrix strengthened by complex carbohydrate fibers.
Particle size and interfacial interactions with adjacent matrices affect the mechanical properties of food
composites.
Food polymers may be soluble in and/or plasticized by water. Water is the most important plasticizer, particularly
in biological systems thereby changing mechanical properties.
The variables include chemical structure, polymer concentration, molecular weight, degree of chain branching, the
extent of ionization (for electrolytes), solution pH, ionic strength and temperature.
Cross-linking of different polymers, protein and polysaccharides, either through chemical covalent bonds or cross-
links through molecular entanglement or hydrogen or ionic bond cross-linking.
Cooking and chewing food alters these physicochemical properties and hence absorption and movement through
the stomach and along the intestine[64]
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Dietary fiber in the upper gastrointestinal tract


Following a meal, the stomach and upper gastrointestinal contents consist of

food compounds
complex lipids/micellar/aqueous/hydrocolloid and hydrophobic phases
hydrophilic phases
solid, liquid, colloidal and gas bubble phases.[65]
Micelles are colloid-sized clusters of molecules which form in conditions as those above, similar to the critical micelle
concentration of detergents.[66] In the upper gastrointestinal tract, these compounds consist of bile acids and di- and
monoacyl glycerols which solubilize triacylglycerols and cholesterol.[66]

Two mechanisms bring nutrients into contact with the epithelium:

1. intestinal contractions create turbulence; and


2. convection currents direct contents from the lumen to the epithelial surface.[67]
The multiple physical phases in the intestinal tract slow the rate of absorption compared to that of the suspension
solvent alone.

1. Nutrients diffuse through the thin, relatively unstirred layer of fluid adjacent to the epithelium.
2. Immobilizing of nutrients and other chemicals within complex polysaccharide molecules affects their release and
subsequent absorption from the small intestine, an effect influential on the glycemic index.[67]
3. Molecules begin to interact as their concentration increases. During absorption, water must be absorbed at a rate
commensurate with the absorption of solutes. The transport of actively and passively absorbed nutrients across
epithelium is affected by the unstirred water layer covering the microvillus membrane.[67]
4. The presence of mucus or fiber, e.g., pectin or guar, in the unstirred layer may alter the viscosity and solute
diffusion coefficient.[65]
Adding viscous polysaccharides to carbohydrate meals can reduce post-prandial blood glucose concentrations. Wheat
and maize but not oats modify glucose absorption, the rate being dependent upon the particle size. The reduction in
absorption rate with guar gum may be due to the increased resistance by viscous solutions to the convective flows
created by intestinal contractions.

Dietary fiber interacts with pancreatic and enteric enzymes and their substrates. Human pancreatic enzyme activity is
reduced when incubated with most fiber sources. Fiber may affect amylase activity and hence the rate of hydrolysis of
starch. The more viscous polysaccharides extend the mouth-to-cecum transit time; guar, tragacanth and pectin being
slower than wheat bran.[68]

Fiber in the colon


The colon may be regarded as two organs,

1. the right side (cecum and ascending colon), a fermenter.[69] The right side of the colon is involved in nutrient
salvage so that dietary fiber, resistant starch, fat and protein are utilized by bacteria and the end-products
absorbed for use by the body
2. the left side (transverse, descending, and sigmoid colon), affecting continence.
The presence of bacteria in the colon produces an ‘organ’ of intense, mainly reductive, metabolic activity, whereas the
liver is oxidative. The substrates utilized by the cecum have either passed along the entire intestine or are biliary
excretion products. The effects of dietary fiber in the colon are on

1. bacterial fermentation of some dietary fibers


2. thereby an increase in bacterial mass
3. an increase in bacterial enzyme activity
4. changes in the water-holding capacity of the fiber residue after fermentation
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Enlargement of the cecum is a common finding when some dietary fibers are fed and this is now believed to be normal
physiological adjustment. Such an increase may be due to a number of factors, prolonged cecal residence of the fiber,
increased bacterial mass, or increased bacterial end-products. Some non-absorbed carbohydrates, e.g. pectin, gum
arabic, oligosaccharides and resistant starch, are fermented to short-chain fatty acids (chiefly acetic, propionic and n-
butyric), and carbon dioxide, hydrogen and methane. Almost all of these short-chain fatty acids will be absorbed from
the colon. This means that fecal short-chain fatty acid estimations do not reflect cecal and colonic fermentation, only
the efficiency of absorption, the ability of the fiber residue to sequestrate short-chain fatty acids, and the continued
fermentation of fiber around the colon, which presumably will continue until the substrate is exhausted. The
production of short-chain fatty acids has several possible actions on the gut mucosa. All of the short-chain fatty acids
are readily absorbed by the colonic mucosa, but only acetic acid reaches the systemic circulation in appreciable
amounts. Butyric acid appears to be used as a fuel by the colonic mucosa as the preferred energy source for colonic
cells.

Dietary fiber and cholesterol metabolism


Dietary fiber may act on each phase of ingestion, digestion, absorption and excretion to affect cholesterol
metabolism,[70] such as the following:

1. Caloric energy of foods through a bulking effect


2. Slowing of gastric emptying time
3. A glycemic index type of action on absorption
4. A slowing of bile acid absorption in the ileum so bile acids escape through to the cecum
5. Altered or increased bile acid metabolism in the cecum
6. Indirectly by absorbed short-chain fatty acids, especially propionic acid, resulting from fiber fermentation affecting
the cholesterol metabolism in the liver.
7. Binding of bile acids to fiber or bacteria in the cecum with increased fecal loss from the entero-hepatic circulation.
An important action of some fibers is to reduce the reabsorption of bile acids in the ileum and hence the amount and
type of bile acid and fats reaching the colon. A reduction in the reabsorption of bile acid from the ileum has several
direct effects.

1. Bile acids may be trapped within the lumen of the ileum either because of a high luminal viscosity or because of
binding to a dietary fiber.[71]
2. Lignin in fiber adsorbs bile acids, but the unconjugated form of the bile acids are adsorbed more than the
conjugated form. In the ileum where bile acids are primarily absorbed the bile acids are predominantly
conjugated.
3. The enterohepatic circulation of bile acids may be altered and there is an increased flow of bile acids to the
cecum, where they are deconjugated and 7alpha-dehydroxylated.
4. These water-soluble form, bile acids e.g., deoxycholic and lithocholic are adsorbed to dietary fiber and an
increased fecal loss of sterols, dependent in part on the amount and type of fiber.
5. A further factor is an increase in the bacterial mass and activity of the ileum as some fibers e.g., pectin are
digested by bacteria. The bacterial mass increases and cecal bacterial activity increases.
6. The enteric loss of bile acids results in increased synthesis of bile acids from cholesterol which in turn reduces
body cholesterol.
The fibers that are most effective in influencing sterol metabolism (e.g. pectin) are fermented in the colon. It is
therefore unlikely that the reduction in body cholesterol is due to adsorption to this fermented fiber in the colon.

1. There might be alterations in the end-products of bile acid bacterial metabolism or the release of short chain fatty
acids which are absorbed from the colon, return to the liver in the portal vein and modulate either the synthesis of
cholesterol or its catabolism to bile acids.
2. The prime mechanism whereby fiber influences cholesterol metabolism is through bacteria binding bile acids in
the colon after the initial deconjugation and dehydroxylation. The sequestered bile acids are then excreted in
feces.[72]
3. Fermentable fibers e.g., pectin will increase the bacterial mass in the colon by virtue of their providing a medium
for bacterial growth.
4. Other fibers, e.g., gum arabic, act as stabilizers and cause a significant decrease in serum cholesterol without
increasing fecal bile acid excretion.
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Dietary fiber and fecal weight


Feces consist of a plasticine-like material, made up of water, bacteria,
lipids, sterols, mucus and fiber.

1. Feces are 75% water; bacteria make a large contribution to the dry
weight, the residue being unfermented fiber and excreted compounds.
Kids eating dietary fiber food
2. Fecal output may vary over a range of between 20 and 280 g over 24
hours. The amount of feces egested a day varies for any one
individual over a period of time.
3. Of dietary constituents, only dietary fiber increases fecal weight.
Water is distributed in the colon in three ways:

1. Free water which can be absorbed from the colon.


2. Water that is incorporated into bacterial mass.
3. Water that is bound by fiber.
Fecal weight is dictated by:

1. the holding of water by the residual dietary fiber after fermentation.


2. the bacterial mass.
3. There may also be an added osmotic effect of products of bacterial fermentation on fecal mass.
Wheat bran is minimally fermented and binds water and when added to the diet increases fecal weight in a predictable
linear manner and decreases intestinal transit time. The particle size of the fiber is all-important, coarse wheat bran
being more effective than fine wheat bran. The greater the water-holding capacity of the bran, the greater the effect on
fecal weight. For most healthy individuals, an increase in wet fecal weight, depending on the particle size of the bran,
is generally of the order of 3–5 g/g fiber. The fermentation of some fibers results in an increase in the bacterial content
and possibly fecal weight. Other fibers, e.g. pectin, are fermented and have no effect on stool weight.

Effects of fiber intake


Research has shown that fiber may benefit health in several different ways. Lignin and probably related materials that
are resistant to enzymatic degradation, diminish the nutritional value of foods.[73]

Color coding of table entries:

Both Applies to both soluble and insoluble fiber


Soluble Applies to soluble fiber only
Insoluble Applies to insoluble fiber only

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Effects[1][74]
Increases food volume without increasing caloric content to the same extent as digestible
carbohydrates, providing satiety which may reduce appetite.
Attracts water and forms a viscous gel during digestion, slowing the emptying of the
stomach and intestinal transit, shielding carbohydrates from enzymes, and delaying
absorption of glucose,[1][75] which lowers variance in blood sugar levels

Lowers total and LDL cholesterol, which may reduce the risk of cardiovascular disease[1]
Regulates blood sugar, which may reduce glucose and insulin levels in diabetic patients
and may lower risk of diabetes[1][76]
Speeds the passage of foods through the digestive system, which facilitates regular
defecation
Adds bulk to the stool, which alleviates constipation

Balances intestinal pH[77] and stimulates intestinal fermentation production of short-chain


fatty acids[1]

Fiber does not bind to minerals and vitamins and therefore does not restrict their absorption, but rather evidence
exists that fermentable fiber sources improve absorption of minerals, especially calcium.[78][79][80] Some plant foods
can reduce the absorption of minerals and vitamins like calcium, zinc, vitamin C, and magnesium, but this is caused by
the presence of phytate (which is also thought to have important health benefits), not by fiber.[81]

Research
A study of 388,000 adults ages 50 to 71 for nine years found that the highest consumers of fiber were 22% less likely to
die over this period.[82] In addition to lower risk of death from heart disease, adequate consumption of fiber-
containing foods, especially grains, was also associated with reduced incidence of infectious and respiratory illnesses,
and, particularly among males, reduced risk of cancer-related death.

An experiment designed with a large sample and conducted by NIH-AARP Diet and Health Study studied the
correlation between fiber intake and colorectal cancer. The analytic cohort consisted of 291,988 men and 197,623
women aged 50–71 years. Diet was assessed with a self-administered food-frequency questionnaire at baseline in
1995–1996; 2,974 incident colorectal cancer cases were identified during five years of follow-up. The result was that
total fiber intake was not associated with colorectal cancer.[83]

Although many researchers believe that dietary fiber intake reduces risk of colon cancer, one study conducted by
researchers at the Harvard School of Medicine of over 88,000 women did not show a statistically significant
relationship between higher fiber consumption and lower rates of colorectal cancer or adenomas.[84] Similarly, a 2010
study of 58,279 men found no relationship between dietary fiber and colorectal cancer.[85]

Dietary fiber and obesity


Dietary fiber has many functions in diet, one of which may be to aid in energy intake control and reduced risk for
development of obesity. The role of dietary fiber in energy intake regulation and obesity development is related to its
unique physical and chemical properties that aid in early signals of satiation and enhanced or prolonged signals of
satiety. Early signals of satiation may be induced through cephalic- and gastric-phase responses related to the bulking
effects of dietary fiber on energy density and palatability, whereas the viscosity-producing effects of certain fibers may
enhance satiety through intestinal-phase events related to modified gastrointestinal function and subsequent delay in
fat absorption. In general, fiber-rich diets, whether achieved through fiber supplementation or incorporation of high
fiber foods into meals, have a reduced energy density compared with high fat diets. This is related to fiber’s ability to

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add bulk and weight to the diet. There are also indications that women may be more sensitive to dietary manipulation
with fiber than men. The relationship of body weight status and fiber effect on energy intake suggests that obese
individuals may be more likely to reduce food intake with dietary fiber inclusion.[86]

Guidelines on fiber intake


Current recommendations from the United States National Academy of Sciences, Institute of Medicine, state that for
Adequate Intake, adult men ages 14–50 consume 38 grams of dietary fiber per day, men 51 and older 30 grams,
women ages 19–50 to consume 25 grams per day, women 51 and older 21 grams.[2][81]

The AND (Academy of Nutrition and Dietetics, previously ADA) recommends a minimum of 20–35 g/day for a healthy
adult depending on calorie intake (e.g., a 2000 Cal/8400 kJ diet should include 25 g of fiber per day). The AND's
recommendation for children is that intake should equal age in years plus 5 g/day (e.g., a 4 year old should consume 9
g/day). No guidelines have yet been established for the elderly or very ill. Patients with current constipation, vomiting,
and abdominal pain should see a physician. Certain bulking agents are not commonly recommended with the
prescription of opioids because the slow transit time mixed with larger stools may lead to severe constipation, pain, or
obstruction.

As of 2018, the British Nutrition Foundation has recommended a minimum fiber intake of 30 grams per day for
healthy adults.[87]

Fiber recommendations

United States
On average, North Americans consume less than 50% of the dietary fiber levels recommended for good health. In the
preferred food choices of today's youth, this value may be as low as 20%, a factor considered by experts as contributing
to the obesity levels seen in many developed countries.[88] Recognizing the growing scientific evidence for
physiological benefits of increased fiber intake, regulatory agencies such as the Food and Drug Administration (FDA)
of the United States have given approvals to food products making health claims for fiber. The FDA classifies which
ingredients qualify as being "fiber", and requires for product labeling that a physiological benefit is gained by adding
the fiber ingredient.[89] As of 2008, the FDA approved health claims for qualified fiber products to display labeling
that regular consumption may reduce blood cholesterol levels – which can lower the risk of coronary heart disease[90]
– and also reduce the risk of some types of cancer.[91]

Viscous fiber sources gaining FDA approval are:

Psyllium seed husk (7 grams per day)


Beta-glucan from oat bran, whole oats, oatrim, or rolled oats (3 grams per day)
Beta-glucan from whole grain or dry-milled barley (3 grams per day)
Other examples of bulking fiber sources used in functional foods and supplements include cellulose, guar gum and
xanthan gum. Other examples of fermentable fiber sources (from plant foods or biotechnology) used in functional
foods and supplements include resistant starch, inulin, fructans, fructooligosaccharides, oligo- or polysaccharides, and
resistant dextrins, which may be partially or fully fermented.

Consistent intake of fermentable fiber may reduce the risk of chronic diseases.[92][93][94] Insufficient fiber in the diet
can lead to constipation.[95]

United Kingdom

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In 2018, the British Nutrition Foundation issued a statement to define dietary fiber more concisely and list the
potential health benefits established to date, while increasing its recommended daily intake to 30 grams for healthy
adults.[1] Statement: 'Dietary fibre' has been used as a collective term for a complex mixture of substances with
different chemical and physical properties which exert different types of physiological effects.

The use of certain analytical methods to quantify dietary fiber by nature of its indigestibility results in many other
indigestible components being isolated along with the carbohydrate components of dietary fiber. These components
include resistant starches and oligosaccharides along with other substances that exist within the plant cell structure
and contribute to the material that passes through the digestive tract. Such components are likely to have
physiological effects.

Diets naturally high in fiber can be considered to bring about several main physiological consequences:[1]

increases fecal bulk and helps prevent constipation by decreasing fecal transit time in the large intestine
improves gastrointestinal health
improves glucose tolerance and the insulin response following a meal
increases colonic fermentation and short-chain fatty acid production
positively modulates colonic microflora
reduces hyperlipidemia, hypertension, and other coronary heart disease risk factors
increases satiety and hence may contribute to weight management
Fiber is defined by its physiological impact, with many heterogenous types of fibers. Some fibers may primarily impact
one of these benefits (i.e., cellulose increases fecal bulking and prevents constipation), but many fibers impact more
than one of these benefits (i.e., resistant starch increases bulking, increases colonic fermentation, positively modulates
colonic microflora and increases satiety and insulin sensitivity).[3][4] The beneficial effects of high fiber diets are the
summation of the effects of the different types of fiber present in the diet and also other components of such diets.

Defining fiber physiologically allows recognition of indigestible carbohydrates with structures and physiological
properties similar to those of naturally occurring dietary fibers.[1]

Fiber and fermentation


The American Association of Cereal Chemists has defined soluble fiber this way: "the edible parts of plants or similar
carbohydrates resistant to digestion and absorption in the human small intestine with complete or partial
fermentation in the large intestine."[96] In this definition:

Edible parts of plants


indicates that some parts of a plant we eat—skin, pulp, seeds, stems, leaves, roots—contain
fiber. Both insoluble and soluble sources are in those plant components.
Carbohydrates
complex carbohydrates, such as long-chained sugars also called starch, oligosaccharides,
or polysaccharides, are sources of soluble fermentable fiber.
Resistant to digestion and absorption in the human small intestine
foods providing nutrients are digested by gastric acid and digestive enzymes in the stomach
and small intestine where the nutrients are released then absorbed through the intestinal
wall for transport via the blood throughout the body. A food resistant to this process is
undigested, as insoluble and soluble fibers are. They pass to the large intestine only affected
by their absorption of water (insoluble fiber) or dissolution in water (soluble fiber).
Complete or partial fermentation in the large intestine
the large intestine comprises a segment called the colon within which additional nutrient
absorption occurs through the process of fermentation. Fermentation occurs by the action of
colonic bacteria on the food mass, producing gases and short-chain fatty acids. It is these
short-chain fatty acids—butyric, acetic (ethanoic), propionic, and valeric acids—that scientific
evidence is revealing to have significant health properties.[97]

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As an example of fermentation, shorter-chain carbohydrates (a type of fiber found in legumes) cannot be digested, but
are changed via fermentation in the colon into short-chain fatty acids and gases (which are typically expelled as
flatulence).

According to a 2002 journal article,[92] fiber compounds with partial or low fermentability include:

cellulose, a polysaccharide
hemicellulose, a polysaccharide
lignans, a group of phytoestrogens
plant waxes
fiber compounds with high fermentability include:

resistant starches
beta-glucans, a group of polysaccharides
pectins, a group of heteropolysaccharides
natural gums, a group of polysaccharides
inulins, a group of polysaccharides
oligosaccharides

Short-chain fatty acids


When fermentable fiber is fermented, short-chain fatty acids (SCFA) are produced. SCFAs are involved in numerous
physiological processes promoting health, including:[97]

stabilize blood glucose levels by acting on pancreatic insulin release and liver control of glycogen breakdown
stimulate gene expression of glucose transporters in the intestinal mucosa, regulating glucose absorption[98]
provide nourishment of colonocytes, particularly by the SCFA butyrate
suppress cholesterol synthesis by the liver and reduce blood levels of LDL cholesterol and triglycerides
responsible for atherosclerosis
lower colonic pH (i.e., raises the acidity level in the colon) which protects the lining from formation of colonic
polyps and increases absorption of dietary minerals
stimulate production of T helper cells, antibodies, leukocytes, cytokines, and lymph mechanisms having crucial
roles in immune protection
improve barrier properties of the colonic mucosal layer, inhibiting inflammatory and adhesion irritants, contributing
to immune functions
SCFAs that are absorbed by the colonic mucosa pass through the colonic wall into the portal circulation (supplying the
liver), and the liver transports them into the general circulatory system.

Overall, SCFAs affect major regulatory systems, such as blood glucose and lipid levels, the colonic environment, and
intestinal immune functions.[99][100]

The major SCFAs in humans are butyrate, propionate, and acetate, where butyrate is the major energy source for
colonocytes, propionate is destined for uptake by the liver, and acetate enters the peripheral circulation to be
metabolized by peripheral tissues.

FDA-approved health claims


The United States FDA allows manufacturers of foods containing 1.7 g per serving of psyllium husk soluble fiber or
0.75 g of oat or barley soluble fiber as beta-glucans to claim that regular consumption may reduce the risk of heart
disease.[101]

The FDA statement template for making this claim is: Soluble fiber from foods such as [name of soluble fiber source,
and, if desired, name of food product], as part of a diet low in saturated fat and cholesterol, may reduce the risk of
heart disease. A serving of [name of food product] supplies __ grams of the [necessary daily dietary intake for the

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benefit] soluble fiber from [name of soluble fiber source] necessary per day to have this effect.[101]

Eligible sources of soluble fiber providing beta-glucan include:

Oat bran
Rolled oats
Whole oat flour
Oatrim
Whole grain barley and dry milled barley
Soluble fiber from psyllium husk with purity of no less than 95%
The allowed label may state that diets low in saturated fat and cholesterol and that include soluble fiber from certain of
the above foods "may" or "might" reduce the risk of heart disease.

As discussed in FDA regulation 21 CFR 101.81, the daily dietary intake levels of soluble fiber from sources listed above
associated with reduced risk of coronary heart disease are:

3 g or more per day of beta-glucan soluble fiber from either whole oats or barley, or a combination of whole oats
and barley
7 g or more per day of soluble fiber from psyllium seed husk.[102]
Soluble fiber from consuming grains is included in other allowed health claims for lowering risk of some types of
cancer and heart disease by consuming fruit and vegetables (21 CFR 101.76, 101.77, and 101.78).[101]

In December 2016, FDA approved a qualified health claim that consuming resistant starch from high-amylose corn
may reduce the risk of type 2 diabetes due to its effect of increasing insulin sensitivity. The allowed claim specified:
"High-amylose maize resistant starch may reduce the risk of type 2 diabetes. FDA has concluded that there is limited
scientific evidence for this claim." [103]

See also
Essential nutrient
List of diets
List of macronutrients
List of micronutrients
List of phytochemicals in food
Underweight
Low-fiber/low-residue diet
Methyl cellulose

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