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Oral and Maxillofacial Surgery/Orthodontics

Ovais H Malik

David T Waring, Richard Lloyd, Sangeeta Misra and Elizabeth Paice

An Overview of the Surgical


Correction of Dentofacial
Deformity
Abstract: The correction of severe dentofacial discrepancies involving a combination of orthodontic and surgical therapies (termed ‘orthognathic
treatment’) is commonplace. There is an abundance of evidence within this field but it is often inconsistent. This article is an evidence-based
overview of such treatments and is aimed at the general dental practitioner. It will cover: the timing of treatment; the indications and risks
associated with different surgical osteotomies; the magnitude of surgical movements that can be achieved with these procedures; and
the importance of mandibular autorotation when planning treatment. Orthognathic treatment is considered to be the gold standard for
comprehensive correction of severe dentofacial discrepancies. It is undertaken by a multidisciplinary team of clinicians involving, but not
exclusive to, consultants in orthodontics and oral and maxillofacial surgery in secondary and tertiary medical centres throughout the United
Kingdom.
CPD/Clinical Relevance: It is imperative that general dental practitioners have a good understanding of orthognathic treatment in order to
recognize when such treatments are indicated, to inform the patient of possible treatment modalities and to be able to discuss associated risks
in order to make appropriate referrals. Since treatment timing and magnitude of surgical movements have a profound effect on stability of the
treatment result, these must be carefully considered by all clinicians involved in patient care to minimize relapse potential.
Dent Update 2016; 43: 550–562

Orthognathic treatment is used worldwide The aim of this article is to give


Ovais H Malik, BDS, MSc(Orth), MFDS to correct severe dentofacial anomalies the general dental practitioner an evidence-
RCS(Ed), MOrth RCS(Eng), MOrth RCS(Ed), with the benefits and risks of these being based overview of the surgical procedures
FDS(Orth) RCS(Eng), Consultant in shown in Table 1. There are a multitude involved in orthognathic treatment using
Orthodontics, University of Manchester of maxillary and mandibular osteotomies classical and contemporary literature.
Dental Hospital and Salford Royal NHS and techniques for repositioning the jaws
Foundation Trust, Stott Lane, Manchester,
M6 8HD (ovaismalik@yahoo.com), David T
in three planes of space (Table 2). Some Timing of treatment
are more commonly indicated than others, Most osteotomies in healthy,
Waring, BChD, MDentSci, MFDS RCS(Eng),
some have been modified and refined over non-syndromic individuals are planned
MOrth RCS(Ed), FDS(Orth) RCS(Ed),
time, yet no standardized techniques are following cessation of active facial
Consultant in Orthodontics, University of
practised internationally on any one given growth,1,2,3 which is generally accepted to
Manchester Dental Hospital, Richard Lloyd,
procedure. Consequently, one could ask be at approximately 19 years of age in boys
BDS, MB ChB, FDS RCS, FRCS, Consultant in
which techniques constitute current ‘best and 17 years in girls, although individual
Oral and Maxillofacial Surgery, Salford Royal
practice’. Much of the available evidence is variation does occur. The timing of surgical
NHS Foundation Trust, Sangeeta Misra, BDS,
based on the studies undertaken in the mid correction also depends upon the type
MFDS RCS(Eng), MOrth RCS(Eng), FDS(Orth)
1990s1,2,3 when routine clinical practices, of malocclusion, particularly for Class III
RCS(Ed), Consultant in Orthodontics, Barnsley
General Hospital and Elizabeth Paice, such as intermaxillary fixation (IMF) were skeletal patterns where surgery is deferred
BDS(Hons), MClinDent, MJDF RCS(Eng), rudimentary and research techniques were until 18−20 years in girls and boys to
MOrth RCS(Eng), FTTA in Orthodontics, often flawed by today’s standards. Studies minimize the likelihood of unfavourable late
University of Manchester Dental Hospital and tended to lack sample size calculations, mandibular growth.3 Assessing a patient
Salford Royal NHS Foundation Trust, Stott randomization processes, homogeneity of after cessation of active growth has the
Lane, Manchester, M6 8HD, UK. the test groups or had retrospective or no following advantages:1
control groups.  The full extent of skeletal discrepancy
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Oral and Maxillofacial Surgery/Orthodontics

a
Benefits No improvement Risks

Aesthetic improvement TMJ GA (Mortality and Morbidity)

Masticatory improvement Speech Nerve damage

Improvement in airway Undesirable soft and hard tissue


patency changes

Wound infection

Relapse

Speech deterioration in cleft cases


Table 1. Benefits and risks of osteotomies.

Type of Osteotomy Indication


BSSO Mandibular (Md) advancement Mandibular hypoplasia b

BSSO Md setback Mandibular hyperplasia

Md differential setback and advancement + rotation Mandibular asymmetry


Table 2. Indications for mandibular osteotomies.

can be identified; advancement depends upon the following:


 Treatment planning can be undertaken  The extent of skeletal anterio-posterior
to minimize potential for surgical and discrepancy;
orthodontic relapse;  Whether the surgical correction is
 The patient is more mature and thus desired in the maxilla alone or in both
capable of giving valid consent for the jaws;
treatment.  The limit of correction that can be
obtained surgically;
Le Fort I osteotomies  The likelihood of adverse effects upon
nasal morphology. Figure 1. (a) Le Fort I maxillary osteotomy. (b) Le
Indications The scope of stable maxillary Le Fort I maxillary advancement.
Le Fort I maxillary advancement Fort I advancement remains a contentious
This is mainly indicated for the issue as the published data has various
treatment of maxillary hypoplasia (Table drawbacks,4,5,6 such as grouping of samples months of surgery.6
3, Figure 1), most commonly associated with different osteotomy procedures A second approach that may be
with Class III skeletal bases. The magnitude (Le Fort I maxillary advancement − with used to address a severe AP discrepancy
of the advancement is determined by the or without a simultaneous mandibular between the maxilla and mandible is a
need to place the upper incisors in the procedure), heterogeneous samples (mixing bimaxillary osteotomy.4,5 Depending on
relationship to the rest of the face and the of cleft and non-cleft osteotomy cases), the severity and nature of the discrepancy,
upper lip. This is generally the extent of pooling of data irrespective of direction of this will involve a combination of maxillary
negative overjet plus the desired positive maxillary movement following the Le Fort and mandibular advancement or setback.
overjet of 2−3 mm after single jaw surgical I osteotomy (forward alone, forward and (Figure 3 a−h).
correction of the maxilla alone. This corrects downward or forward with impaction) or
the incisal relationship and builds in a small type of fixation (intermaxillary fixation ‘IMF’
Le Fort I maxillary setback
or rigid internal fixation ‘RIF’).
amount of relapse correction (Figure 2 a−h). This can be achieved by
The range of surgical
The Le Fort I procedure can also be used removing a triangular wedge of tuberosity
anteroposterior (AP) advancement of
for minor midline (1−2 mm) discrepancies sectioned through the third molar region.7
maxilla has been reported from 2−10 mm
by rotating the maxilla sagittally after the The third molar, if present, may have to
with a mean movement of 4.9 mm.6 Most of
down fracture.1 be removed prior to the tuberositectomy.7
the surgical relapse occurred in the first six
The extent of maxillary However, this procedure is rarely indicated.
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Oral and Maxillofacial Surgery/Orthodontics

Type of Osteotomy Indication f

Le Fort I, II and III Maxillary (Mx) advancement Mx hypoplasia

Mx impaction Vertical Mx Excess (VME)

Mx differential impaction Skeletally caused AOB

Mx differential rotation Mx asymmetry

Mx expansion (SARPE) Transverse Mx hypoplasia

Table 3. Indications for maxillary osteotomies.

a
c

d
g

e h

Le Fort I maxillary impaction


This is indicated for the
correction of excessive gingival display (>3
mm) on smiling,8 which is seen with vertical
maxillary excess (VME) when the anterior +
posterior face height is increased7 (Figure
4), and for the surgical correction of anterior
open bite (AOB) of skeletal aetiology7
(Figure 5). The degree of impaction is
determined by the amount of gingival
show at rest and on smiling and the upper
lip length.7 There is no established limit of
maximum maxillary impaction, but up to
Figure 2. (a-d) Extra-oral and intra-oral views of a patient with maxillary deficiency. (e-h) Extra-oral 8 mm of posterior maxillary intrusion has
and intra-oral views of the patient in (a−d) after pre-surgical orthodontic treatment and a Le Fort I
been reported in the literature.8,9
osteotomy with maxillary advancement.
Maxillary impaction tends to
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Oral and Maxillofacial Surgery/Orthodontics

shorten the upper lip length by up to 25%.7 based on the perception of neuromuscular which is replicated on articulators, mastoid
Condylar resorption of 9−12% has been adaptation which takes place as a air cells and on lateral cephalograms.
reported with Le Fort 1 posterior maxillary compensatory phenomenon immediately Another hypothesis is that autorotation is
impaction and mandibular autorotation.10 following surgery.11,12 It is essential a combination of translation and rotation
to establish the extent of MA as this of the mandible with no constant centre
Mandibular autorotation leads to greater anterior prominence of rotation in the condyle. Autorotation of
of the mandible in the aforementioned the mandible has been reported to cause
The concept of mandibular
circumstances.12 Assessment of the incisor condylar resorption in 9−12% of cases.10
autorotation (MA) with maxillary surgical
position of an autorotated mandible
anterior and/or superior repositioning is
determines if further adjustment of the AP SARPE
maxillary position is required in order to
establish a positive overjet and overbite.12 Indications
a
Research to determine the Surgically Assisted Rapid
centre of autorotation (CR) of the mandible Palatal Expansion (SARPE) is used to treat
was controversial two decades ago.12 The a maxillary transverse deficiency in a
assumed CR is at the centre of the condyle, skeletally mature patient where the mid-

c f

Figure 3. (a−d) Extra-oral and intra-oral views of a patient with maxillary deficiency and mandibular excess requiring bimaxillary osteotomy. (e−h) Extra-oral
and intra-oral views of the patient in (a−d) after a bimaxillary osteotomy involving maxillary advancement and mandibular setback.

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Oral and Maxillofacial Surgery/Orthodontics

palatine suture has closed.13,14 There Le Fort II osteotomy


is lack of definitive guidance on the The indication for a Le Fort II
appropriate age for its use,13,14,15 although osteotomy and maxillary advancement is for
one study has recommended ages the treatment of nasomaxillary hypoplasia
according to gender4 (over 25 years of where the deficiency is at the infra-orbital
age in males, 20 years in females). SARPE margins. This osteotomy accentuates the
is indicated:13,14 prominence of nasal bridge.7
 To treat a transverse maxillary
deficiency of >5 mm in a skeletally Le Fort III (Kufner) osteotomy
mature patient; This operation is specified for
 To provide space for a crowded mild to moderate zygomatico-maxillary
maxillary dentition when extractions hypoplasia where the nose is normal.7
Figure 4. Extra-oral view of a patient with VME
are not indicated; Patients with severe hypo-development and excessive gingival show on smiling.
 To increase the maxillary arch of the middle third of the face who exhibit
perimeter and correct posterior flattening of the suborbital area and a
crossbite (unilateral or bilateral); cheekbones are the suitable candidates for
 To widen a narrow, high-arched palate this osteotomy.7
often associated with oral clefts.
The osteotomy should Segmental Le Fort I osteotomy
be 4−5 mm above the apices of the This type of osteotomy is a
maxillary teeth.14 The areas of resistance useful adjunct when managing transverse
to lateral expansion are anterior support and vertical maxillary discrepancies. The
(piriform aperture pillars), lateral support main indications are:1 b
(zygomatic buttresses), posterior support  One-stage correction of transverse
(pterygoid junction) and medial support maxillary deficiency;
(midpalatine synostosed suture).14 Initial  Correction of anterior open bite where
appliance activation of 0.5−2 mm is there is an obvious discrepancy in the
recommended intra-operatively to ensure occlusal planes of the labial and buccal
that the screw is stable and that there segments; and
is no resistance to its movement.14 A  Correction of severe anterior vertical Figure 5. (a, b) Intra-oral view of a patient with
latent period of up to 7 days has been maxillary excess or deficiency. anterior open bite before and after orthodontic
reported before post-operative activation Segmental osteotomy has treatment and a Le Fort I posterior differential
is started.14,15 Post-operative expansion
also been used to correct small anterio- maxillary impaction.
is typically 0.5 mm−1 mm per day for up
posterior maxillary discrepancies17 as a
to 3 weeks, depending upon the type of
solitary procedure or in conjunction with
screw and extent of transverse expansion
mandibular setback or advancement
desired.14 The achieved expansion is
osteotomies.1 When undertaking a
maintained for 3−6 months while bony
segmental maxillary osteotomy, the
infill occurs at the mid-palatine suture
pre-surgical orthodontics must employ
using a transpalatal arch with arms
segmental mechanics.17 Despite its
palatal to the premolars or a quad-helix
versatility, the level of evidence involving
appliance.14,15
this surgical procedure is low and consists
Patients should be warned
of case reports and audits.17,18 The
about the possible presentation of
associated risks include intra-operative
features such as a midline diastema,
bleeding, oronasal fistula, devitalization
alongside further risks such as nose
of teeth and, on rare occasions, segmental
bleeds, headaches, loosening of the
avasular necrosis.
distractor and palatal ulcerations.13,14,15
Relapse depends upon variables such as
the post-expansion retention regimen, Bilateral Sagittal Split
the time-point when relapse was Osteotomy (BSSO) Figure 6. Bilateral sagittal split osteotomy with
assessed and the amount of skeletal and This procedure, in combination mandibular advancement.
dento-alveolar change achieved with with an advancement procedure, is the
SARPE. The achieved skeletal change most common technique used to correct
(47%) is completely stable whereas the a severe Class II skeletal pattern with is used to correct a moderate to severe
dento-alveolar tipping (53%) immediately mandibular retrognathia (Figure 6) and, Class III skeletal pattern with mandibular
after SARPE is prone to relapse.16 when coupled with a mandibular setback, prognathism (Figure 7).1 The extent of
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Oral and Maxillofacial Surgery/Orthodontics

anteroposterior mandibular movement The mean surgical threshold for to return the proximal segment to its
depends upon: BSSO mandibular setback is 10 mm with original position, again resulting in relapse.19
 The extent of the skeletal discrepancy; no range given.19 A stable result is more Moreover, the inter-condylar width tends
 The limit of correction that can be likely after mandibular setback than after to decrease after BSSO mandibular setback.
obtained surgically; and mandibular advancement, because the This change in axial inclination involves
 Whether the surgical correction is soft tissues are not extensively stretched either medial or lateral rotation of condylar
necessary in mandible alone or when the condyles are set correctly in the axis, however, rigid internal fixation limits
both jaws. fossae before rigid fixation.19 Relapse can be this type of relapse.19 Finally, remaining
expected if the condyles are not properly growth can contribute to relapse. Its effects
located within the fossae at the time of are more pronounced in males with more
a
surgery. If stretched, the pterygomasseteric anti-clockwise (anterior and downward)
sling reverts to normal function when growth rotation.20 In contrast, women show
mandibular mobility resumes, which tends more clockwise rotation.20

c f

b e

Figure 7. (a−d) Extra-oral and intra-oral views of a patient with mandibular hyperplasia requiring BSSO setback. (e–h) Extra-oral and intra-oral views of the
patient in (a−d) after the BSSO setback. Note this patient also had an AOB and therefore required a simultaneous Le Fort I posterior differential maxillary
impaction.

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The widely accepted limit of Figure 8 demonstrates an example of a of 80−100%, although this tends to be
BSSO mandibular advancement is 10 mm21 BSSO with mandibular advancement for temporary rather than permanent.23 Ow
(Figure 8). The risk of horizontal surgical the correction of mandibular retrognathia and Cheung22 reported, in a prospective
relapse increases when the mandible is associated with an increased overjet. randomized clinical trial, that all 23
advanced beyond 7mm.21 The mandibular Condylar resorption associated patients in the test group experienced
plane angle also has an influence on the with BSSO mandibular advancement NSD during the six-week post-operative
horizontal and vertical relapse. High angle has been reported, where one study has period when assessed subjectively (using
cases tend to relapse in the horizontal suggested an incidence of 10%.10 The risk a questionnaire based on visual analogue
plane, whereas low angle cases have a increases with the extent of mandibular scale) and objectively (with light touch,
tendency for vertical relapse.21 There is no advancement, the use of IMF, an increased 2-point discrimination and pain detection
gender predilection to surgical relapse mandibular plane angle and a low facial threshold). The prevalence of long lasting
although it is more frequently seen in height ratio.10 NSD 1 year after surgery is found in 8−10%
female patients that have undergone BSSO The most common complication of the cases.23 This large range of NSD
mandibular advancement procedures. This of BSSO mandibular procedures is incidence exists due to the lack of standard
is thought to be due to a greater proportion neurosensory disturbance (NSD).22,23 methods of neurosensory evaluation
of females than males seeking surgical Whether this iatrogenic effect occurs along and differences in follow-up periods.22,23
correction of their Class II profiles.21 the mandibular canal or at the mental However, long-term satisfaction rates in the
Other factors that contribute foramen, the symptoms are usually varying patients undergoing orthognathic surgery
to relapse include the experience of the degrees of anaesthesia or paraesthesia are high (87−100%) despite these reports
surgeon and patient-related factors such as (numbness) to the lower lip and chin.22,23 of NSD.23
growth and compliance with post-surgical There is a large variation in the reported
orthodontics during the healing process. incidence of iatrogenic NSD with reports
Genioplasty
A genioplasty may be used to
a c correct abnormal chin prominence.21 It may
be undertaken in combination with other
surgical procedures or in isolation. If part
of an orthognathic treatment plan, the
genioplasty may be completed at the same
time as the other osteotomies or postponed
by six months and undertaken separately.24
This delay permits resolution of the facial
swelling and facilitates reassessment of the
facial profile following the primary surgery.
An abnormal chin prominence
can present as:24,25
 An anterio-posterior chin deficiency
(retrogenia);
 Pseudoretrogenia, as seen in Class II
mandibular retrognathia, where the chin
is normal;
 A large or small chin in all three planes of
space (macrogenia or microgenia);
 A midline asymmetry of chin.
b d The horizontal osteotomy
must run 4−5 mm below the apices of
the canines and 3 mm below the mentalis
nerve.24 An isolated genioplasty is effective
for managing mild anterio-posterior
mandibular deficiency of <5 mm.25
The chin can be moved in
all three planes of space using various
procedures:24,25
 Sliding/advancement genioplasty which is
Figure 8. (a, b) Extra-oral and intra-oral views of a patient with Class II malocclusion on a Class II
used for correction of retrogenia without
skeletal base with mandibular hypoplasia. (c, d) Extra-oral and intra-oral views of the patient in (a, b)
any vertical change in the height of the
after BSSO mandibular advancement.
chin;
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Oral and Maxillofacial Surgery/Orthodontics

 Two-tier/stepladder genioplasty which is day.26,28 The distractor is usually activated 4. Hoffman GR, Brennan PA. The
used for large AP correction as the lower by 1 mm at the time of placement followed skeletal stability of one-piece Le Fort
segment is advanced sagittally over an by a latent period which is 7 ± 2 days I osteotomy to advance the maxilla.
already advanced proximal segment; between surgical placement of a distractor Part 1. Stability resulting from non-
 Vertical lengthening genioplasty with and commencement of distraction.26,28 bone grafted rigid fixation. Br J Oral
interpositional bone graft to increase the The rhythm of distraction ranges between Maxillofac Surg 2004; 42: 221−225.
vertical height of the chin; 1−4 times/day.28 The average distraction 5. Hoffman GR, Brennan PA. The
 Vertical reduction/wedge genioplasty achieved in mandible and midface are skeletal stability of one-piece Le Fort
where a segment of bone is removed 16−17 mm and 14 mm, respectively,27 I osteotomy to advance the maxilla.
to reduce the height of the lower facial whereas that for alveolar distraction Part 2. The influence of uncontrollable
third; and osteogenesis was 6.8 ± 2.5 mm (range 3−15 clinical variables. Br J Oral Maxillofac
 Centring/cuneiform genioplasty and mm).28 Some overcorrection is undertaken Surg 2004; 42: 226−230.
hemigenioplasty which are used to compensate for probable relapse 6. Dowling P, Espeland L, Sandvik L,
to correct vertical and horizontal (3 mm).27 Mobarak KA, Hogevold HE. Le Fort
asymmetries. Depending upon the The distraction device is left I maxillary advancement: 3−4 years
extent and location of the asymmetry, in situ after the active distraction period stability and risk factors for relapse.
bone can be resected on the affected for 6−12 weeks to allow the consolidation Am J Orthod Dentofacial Orthop 2005;
side. phase to occur.26,27,28 This is the period 128: 560−567.
A pressure dressing is applied to during which maturation and corticalization 7. Harris M, Hunt N. Fundamentals of
the chin for the support of the soft tissues, of the callus occurs.28 Complications Orthognathic Surgery 2nd edn. London:
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to reduce swelling and achieve definition of dehiscence, transient paraesthesia, inferior 8. Moloney F, West RA, McNeill W. Surgical
labiomental fold.24 dental and facial nerve injuries, haematoma, correction of vertical maxillary excess:
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Distraction Osteogenesis (DO)
and relapse.26,27,28 following superior repositioning of the
is a bone-lengthening process by gradual
maxilla by Le Fort I osteotomy. Am J
mechanical separation of iatrogenically
separated bony fragments. This procedure Summary Orthod Dentofacial Orthop 1987; 92:
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10. Papadaki ME, Tayebaty F, Kaban LB,
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Torulis MJ. Condylar resorption. Oral
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11. Wessberg G, Washburn MC, LaBanc
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JP, Epker BN. Autorotation of the
Distraction osteogenesis may available for the correction of severe
mandible: effect of surgical superior
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mandibular resting posture. Am J
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Oral and Maxillofacial Surgery/Orthodontics

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Craniofacial Growth Series. McNamara Treatment of Dentofacial Anomalies. 1−7.

Book Review evaluation. been considered to be highly suitable


Geoffrey Knight, again from for use in children, so chapter 6 by David
Glass-Ionomers in Dentistry. Dr Sharanbir
Australia, provides chapter 3 and gives Manton from Melbourne and Katie Bach
Sidhu (ed). Switzerland: Springer International
readers a beautifully illustrated look at from Auckland is highly relevant, with a
Publishing, 2016 (151pp, £86.00 h/b) ISBN:
contemporary uses of glass-ionomer well-worded warning – ‘due to the apparent
978-3-319-22623-5.
materials, including interproximal slot and simplicity of the use of these materials, they
tunnel restorations (although this reviewer are also prone to misuse’! The final chapter,
Glass-ionomer materials, first
had considered the latter as being history!) by Joshua Cheetham of Bayswater, Australia,
introduced in the 1970s, play an important and the co-cure method of bonding gives the reader a glimpse toward the future
role in restorative dentistry today, in a wide auto-cure glass-ionomer cements to resin of glass-ionomer materials, with details of the
variety of applications. In order to provide an composite. possible methods which might be employed
in-depth review of this subject, the editor of Our very own Avi Banerjee has in order to improve their physical properties
this book, Dr Sharanbir Sidhu, has brought written an interesting chapter on the use – such as spherical particles and/or glass
together eight experts in the field from across of glass-ionomer materials in minimum fibre reinforcement, and discusses possible
the world. intervention (MI) caries management and avenues for improvement in properties
The book follows a logical order, ART, central to this being the potential for such as wear resistance. Surprisingly, there
starting with the history of glass-ionomer remineralization of demineralized carious appears to be no mention of the idea of heat
materials and their development at the dentine and the associated role of these curing glass-ionomers, a concept designed
Laboratory of the Government Chemist in cements in MI management of deep caries. to improve the physical properties of glass-
London as part of work on the setting of Chapter 5, written by Josette ionomers and which seems to be the subject
dental silicate cements. Camilleri from Malta, deals with the uses of increasing research.
Chapter 2, by Michael Burrow of glass-ionomer materials in endodontics, There is no question that the
from Melbourne, provides details of the perhaps not something that these materials book fulfils the objective of the author,
physical properties of glass-ionomer materials are famed for. Examples are given of root- namely to describe the continuing and new
before moving on to the clinically-relevant end fillings and perforation repairs using roles of glass-ionomer cements in restorative
aspect of restoration longevity. This chapter glass-ionomer, although the chapter ends dentistry. It provides a useful and detailed
includes a large table on the performance of somewhat negatively in a statement that evaluation of the current status of these
glass-ionomers in non-carious cervical lesions research has indicated that ‘they have been materials and will be of value to academics
(perhaps their most common use in the UK?), outperformed by other materials that have been and practitioners alike.
with the data indicating annual loss rates of developed over the years’… F J Trevor Burke
2.7% in a 13-year study and 2.4% in a 10-year Glass-ionomer materials have Editorial Director, Dental Update
562 DentalUpdate July/August 2016
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