Sie sind auf Seite 1von 10

R E V I E W

Drug and Alcohol Review (May 2011), 30, 255–263


DOI: 10.1111/j.1465-3362.2011.00324.x

Recent trends in pharmaceutical drug use among frequent injecting


drug users, frequent methamphetamine users and frequent ecstasy
users in New Zealand, 2006–2009 dar_324 255..263

CHRIS WILKINS, PAUL SWEETSUR & RICHARD GRIFFITHS

SHORE and Whariki Research Centre, School of Public Health, Massey University, Auckland, New Zealand

Abstract
Aims. To examine the rates of pharmaceutical drug use, and level of prescription use and injection of pharmaceutical
drugs, by frequent injecting drug users (IDU), frequent methamphetamine users and frequent ecstasy users in New
Zealand for 2006–2009. Design and method. The paper draws on findings from the 2006, 2007, 2008 and 2009
Illicit Drug Monitoring System (IDMS). The IDMS interviews three groups of frequent illegal drug users (i.e. IDU,
methamphetamine users and ecstasy users) from the three main cities of New Zealand using purposive sampling and
‘snowballing’. Results. Pharmaceutical morphine rather than heroin was the principal opioid used by the IDU. Few
of the IDU or frequent methamphetamine users had prescriptions to use morphine. A lower proportion of the IDU
had a prescription to use morphine in 2009 compared to 2008. The injection of methadone by IDU and metham-
phetamine users was common. A higher proportion of the IDU had injected methadone in 2009 compared to
previous years. A higher proportion of the IDU had used oxycodone in 2009 compared to 2008 and prescription use
of oxycodone by IDU was very low. All three groups of frequent drug users were involved in the extra-medical use
of methylphenidate and benzodiazepines. Discussion and conclusion. Extra-medical use of pharmaceuticals
occurred among all three groups of frequent illegal drug users to varying degrees. Differences between the three
groups in the level and type of extra-medical pharmaceutical drug use suggest that different control strategies may
be effective for each group. [Wilkins C, Sweetsur P, Griffiths R. Recent trends in pharmaceutical drug use among
frequent injecting drug users, frequent methamphetamine users and frequent ecstasy users in New Zealand,
2006–2009. Drug Alcohol Rev 2011;30:255–263]

Key words: Pharmaceutical drug use, frequent injecting drug users, frequent methamphetamine users, frequent
ecstasy users, New Zealand.

increasing levels of prescribing by medical professionals


Introduction
and in particular psychiatrists; and greater private
There is growing awareness worldwide of the issue of access to pharmaceutical drugs via the Internet [2–4].
extra-medical use of pharmaceuticals [1]. A number of Much attention has been given to the extra-medical use
factors have contributed to the problem in the past few of pharmaceutical opioids in a number of countries in
decades including: the marketing of pharmaceuticals to recent years, with particular concern about the leakage
medical professionals by the pharmaceutical industry; of diverted pharmaceutical opioids to injecting illegal
marketing campaigns by pharmaceutical companies drug users [5]. Less is known about the extra-medical
raising awareness of disorders and the drugs available to use of pharmaceuticals by other groups of illegal drug
treat them; the involvement of the pharmaceutical users, such as stimulant users and so called party drug
industry in academic research into the efficacy of phar- users.
maceutical products; the introduction of new pharma- In New Zealand, pharmaceutical opioids illicitly
ceutical medications with the potential for abuse; diverted from the medical system have been known to

Chris Wilkins PhD, Senior Researcher, Drugs Team Leader, Paul Sweetsur MSc (Hons), Statistician, Richard Griffiths PhD, Researcher.
Correspondence to Dr Chris Wilkins, SHORE and Whariki Research Centre, School of Public Health, P O Box 6137,Wellesley St, Auckland, New
Zealand. Tel: +64 9 366 6136; Fax: +64 9 366 5149; E-mail: c.wilkins@massey.ac.nz

Received 8 April 2010; accepted for publication 9 April 2011.

© 2011 Australasian Professional Society on Alcohol and other Drugs


256 C.Wilkins et al.

be a central source of opioids for injecting drug users pharmaceutical opioids in New Zealand for the years
for many decades [6–9]. The regular supply of heroin 2008–2009.
into New Zealand was substantially disrupted in the
late 1970s by the arrest of ‘Mr Asia’, the New Zealand
head of an international heroin trafficking syndicate Method
[6,7]. New Zealand’s geographical isolation, small The paper presents data from the 2006, 2007, 2008
population and effective border control meant the and 2009 Illicit Drug Monitoring System (IDMS).The
international supply of heroin never fully recovered IDMS interviews approximately 300 frequent illegal
[6,7]. Three sources of opioids emerged in the subse- drug users (i.e. 100 frequent methamphetamine users,
quent decades to replace the international supply of 100 frequent injecting drug users and 100 frequent
heroin to New Zealand: (1) pharmaceutical morphine ecstasy users) each year from the three main urban
diverted from the medical system; (2) ‘homebake’ centres of New Zealand (i.e. Auckland, Wellington and
heroin or morphine manufactured in makeshift labora- Christchurch) using purposive sampling and ‘snowball-
tories from codeine base; and, (3) opium extracted on a ing’ [16,17]. Three separate street-level recruitment
seasonal basis from locally grown opium poppies [6–8]. campaigns are undertaken in each site using promo-
Since the early 2000s, there has been an increase in tional material specifically designed to target each fre-
the use of methamphetamine and ecstasy in New quent drug user group. Respondents are screened for
Zealand [10–12]. Frequent users of methamphetamine eligibility for the drug type they contact the interviewer
and ecstasy in New Zealand have been found to have about. An individual can only be interviewed for one of
different demographic profiles as well as different drug the three frequent drug user groups in a given wave (i.e.
use patterns from the traditional frequent injecting the groups are mutually exclusive). Participants are
drug users. This raises the question of whether these required to be 16 years or older, have used the drug
new drug using groups also have different preferences type of interest or injected a drug approximately
for pharmaceutical drugs than injecting drug users. monthly or more often in the past six months, and have
The current understanding of the extent of the extra- resided in the site location for the past 12 months.
medical use of pharmaceutical drugs in New Zealand is Eligible participants are administered a structured face-
fragmented and incomplete [13]. A serious limitation of to-face interview at a public venue of their choosing.
many of the existing official data sources is the inability
to distinguish between the sanctioned and extra-
medical use of pharmaceutical drugs [13]. Measuring Measures
the level of extra-medical use of pharmaceuticals is in Demographics
itself challenging as extra-medical use can occur during
the process of procurement (i.e. pharmaceutical drugs The frequent drug users were asked about their age,
are obtained through deception, fraud or outright primary ethnicity, employment status, marital status
theft), during the process of administration (i.e. phar- and highest educational qualification.
maceutical drugs intended for oral use are injected,
such as with methadone) or even after pharmaceuticals Drug use
have been legitimately obtained (i.e. sanctioned recipi-
ents of pharmaceuticals sell, trade or give away their The frequent drug users were asked whether they had
pharmaceuticals to others who go on to use them in used a range of drug types in the previous six months.
extra medical ways) [13–15]. Having a prescription to Those who had used a drug were asked if they had
use a pharmaceutical drug in the recipient’s own name injected it in the past six months. In 2008 and 2009,
is one measure of legitimate use, albeit incomplete additional pharmaceutical drug types were added to the
given the subsequent opportunities for extra-medical list of drugs asked about and those frequent drug users
administration and sharing and sale. who reported using a pharmaceutical drug type in the
The aim of this paper is to examine the rate of phar- past six months were asked if they had a ‘prescription
maceutical drug use by frequent injecting drug users, for the drug in their own name’.
frequent methamphetamine users and frequent ecstasy
users in New Zealand for the years 2006–2009. Two
Opioid trends
measures of extra-medical use of pharmaceuticals are
presented in the paper for these groups: (1) use without In the 2008 and 2009 IDMS the frequent drug users
a prescription in the recipients own name; and, (2) were asked if they had any knowledge of four types of
injection of a pharmaceutical drug intended for oral use opioids (i.e. ‘street/illicit morphine’, ‘street/illicit
only. The paper also presents frequent illegal drug methadone’, ‘homebake morphine/heroin’ and
users’ perceptions of the availability and use of different ‘heroin’). Those with knowledge of an opioid type were
© 2011 Australasian Professional Society on Alcohol and other Drugs
Pharmaceutical drug use by frequent illegal drug users 257

asked about its current availability, change in availabil- educational qualifications (Table 1). Seventy-seven
ity and change in the number of people using it, and percent of the frequent methamphetamine users were
were read a set of scale answers for each question. male, their average age was 30 years old, 28% were
Maori, 37% were employed and 30% had no educa-
tional qualifications. Seventy percent of the frequent
Analysis ecstasy users were male, their average age was 23 years
To ensure consistent comparisons between years we old, 86% were European, 54% were students and 97%
applied fixed weights to the four annual IDMS samples had an educational qualification. In 2009, the frequent
based on the average distribution of the total sample by injecting drug users were more likely than the frequent
location and average distribution of the total sample by methamphetamine users to be female (37% vs. 23%,
the three frequent drug user groups for 2006–2008. P = 0.0260), older (38 years vs. 30 years, P < 0.0001)
The rate of drug use in the previous six months in 2009 and to be unemployed or on a sickness benefit (79% vs.
was compared to the rate of drug use in 2008, 2007 and 51%, P = 0.0003) (Table 1). The frequent ecstasy users
2006 using logistic regression. We fitted year as a cat- were more likely than the frequent methamphetamine
egorical variable to predict use of a given drug in the users to be younger (23 years vs. 30 years, P < 0.0001),
previous six months. Statistically significant differences European (86% vs. 68%, P = 0.0024), to be students
are noted at the bottom of each table and discussed in (54% vs. 12%, P = 0.0003) and to have an educational
the text. We compared perceptions of current availabil- qualification (97% vs. 70%, P < 0.0001). The frequent
ity, change in availability and change in the number of injecting drug users were older in 2009 compared to
users between the four opioid drug types for 2009. To 2006 (38 years vs. 32 years, P < 0.0001). The frequent
do this for current availability, the categories ‘very easy’ ecstasy users were more likely to be of Maori ethnicity
and ‘easy’ were combined into one easy category and in 2009 compared to 2006 (11% vs. 3%, P = 0.0294).
the ‘difficult’ and ‘very difficult’ categories were com-
bined into one difficult category. The new combined
‘easy’ and combined ‘difficult’ categories were then Drug use
compared between each of the four opioid drug types.
For ‘change in availability’, the ‘more difficult’ category The drug types most commonly used by the frequent
was compared to a combination of the ‘easier’, ‘stable’ injecting drug users in the previous six months in 2009
and ‘fluctuates’ categories. For ‘change in use’, the ‘less’ were tobacco (88%), methadone (73%), cannabis
category was compared to a combination of the ‘same’ (72%), morphine (62%), alcohol (60%) and metham-
and ‘more’ categories. Chi-square analysis was used to phetamine (50%). High proportions of the frequent
test for these differences. If the overall chi-square test injecting drug users had used pharmaceutical drugs
was statistically significant at the alpha = 0.05 level, such as methadone, morphine, benzodiazepines and
chi-square tests between each pair-wise combination of methylphenidate (Ritalin) over the four years of survey-
the four opioid drug types were conducted. The six ing (Table 2). Only approximately one-fifth of the fre-
p-values obtained from the pair-wise tests between the quent injecting drug users had used heroin during these
opioid drug types were adjusted for multiple compari- years. A higher proportion of frequent injecting drug
sons by using the Bonferroni-Holm step-down method. users had used oxycodone in 2009 compared to 2008
We also compared the current availability, change in (18% vs. 9%, P = 0.0341). A higher proportion of the
availability and change in use categories for each opioid frequent injecting drug users who had used methadone
between 2008 to 2009.These tests were also completed had injected it in 2009 compared to 2006 (80% vs.
using Chi-square analysis. Rates of drug use and demo- 65%, P = 0.048) and in 2009 compared to 2007 (80%
graphic variables were produced with 95% confidence vs. 63%, P = 0.0221). Nearly all those frequent inject-
intervals except in cases where the ‘yes’ or ‘no’ results ing drug users who had used methylphenidate over the
were very high or very low and consequently there previous four years had injected it (i.e. 89% in 2006,
insufficient numbers (e.g. only 1% of frequent ecstasy 94% in 2007, 98% in 2008 and 98% in 2009). In 2009,
users used methadone in the previous six months). high proportions of the frequent injecting drug users
reported having ‘prescriptions in their own names’ for
anti-depressants (95% of those who had used them in
Results the previous six months) and methadone (67%). Some
of the frequent injecting drug users had prescriptions
Demographics
for codeine (41%) and benzodiazepines (41%) in 2009.
In 2009, 63% of the frequent injecting drug users were Very few injecting drug users had prescriptions for oxy-
male, their average age was 38 years old, 77% were codone (0%), methylphenidate (2%), and morphine
European, 79% were unemployed and 31% had no (6%) in 2009. A lower proportion of injecting drug
© 2011 Australasian Professional Society on Alcohol and other Drugs
258
C.Wilkins et al.

Table 1. Demographic profile of frequent drug user groups, 2006–2009

Frequent injecting drug users Frequent methamphetamine users Frequent ecstasy users

(95% Confidence 2006 2007 2008 2009 2006 2007 2008 2009 2006 2007 2008 2009
Interval) (n = 93) (n = 109) (n = 132) (n = 99) (n = 114) (n = 110) (n = 137) (n = 105) (n = 111) (n = 105) (n = 135) (n = 111)

Male (%) 55 63 73 63 71 75 75 77 64 69 62 70
(49,65) (53,72) (65,80) (53,72) 62,79) (67,83) (66,81) (68,84) (55,73) (60,77) (54,70) (61,78)

© 2011 Australasian Professional Society on Alcohol and other Drugs


Mean age (years) 32 36 37 38* 30 31 30 30 23 23 23 23
(30,34) (34,38) (35,39) (36,40) (29,32) (29,33) (28,32) (28,31) (22,24) (22,24) (22,24) (22,23)
European (%) 79 82 70 77 71 67 68 68 96 90 87 86
(69,86) (73,88) (62,78) (68,84) (62,79) (58,76) (59,75) (59,77) (90,98) (83,94) (80,91) (78,91)
Maori (%) 19 16 25 20 22 25 28 28 3 5 8 11*
(12,28) (10,25) (19,34) (14,29) (16,31) (18,34) (21,36) (20,37) (1,8) (2,11) (4,13) (6,18)
Unemployed (%) 68 76 81 79 64 63 51 51 6 17 6 6
(58,77) (68,84) (74,88) (70,87) (54,73) (53,72) (42,60) (42,61) (2,11) (10,25) (2,11) (2,10)
Employed (%) 29 23 15 19 23 31 43 37 49 27 31 40
(20,39) (15,31) (9,22) (11,28) (15,31) (22,40) (34,51) (27,46) (40,59) (19,36) (22,39) (31,50)
Student (%) 3 1 4 2 14 7 6 12 44 55 63 54
(0,7) (0,3) (1,8) (0,5) (7,20) (2,12) (2,10) (6,18) (35,54) (46,65) (55,72) (44,63)
Educational 64 58 64 69 63 67 74 70 97 93 96 97
qualification (%) (53,73) (48,67) (55,73) (59,77) (54,72) (57,75) (65,81) (60,78) (92,99) (86,97) (90,98) (91,99)
Single marital status 39 45 49 47 57 40 57 47 50 66 53 56
(%) (29,49) (36,55) (40,57) (37,57) (48,66) (31,50) (49,65) (38,57) (41,60) (57,75) (45,62) (46,65)

*Statistically significant difference between 2009 and 2006 result at the P < 0.05 level.
Table 2. Selected drug types used by frequent illegal drug users in the past six months (pharmaceutical drug types highlighted), 2006–2009
Frequent injecting drug users Frequent methamphetamine users Frequent ecstasy users

2006 2007 2008 2009 2006 2007 2008 2009 2006 2007 2008 2009
Use in past Use in past Use in past Use in past Use in past Use in past Use in past Use in past Use in past Use in past Use in past Use in past
six months six months six months six months six months six months six months six months six months six months six months six months
Drug type (%) (n = 93) (%) (n = 109) (%) (n = 132) (%) (n = 99) (%) (n = 114) (%) (n = 110) (%) (n = 137) (%) (n = 105) (%) (n = 111) (%) (n = 105) (%) (n = 135) (%) (n = 111)

Opioids
Methadone 74 71 73 73 16 27 22 21 2 3 2 1
(64,82) (62,79) (65,80) (64,81) (10,24) (20,37) (16,30) (14,30)
Morphine NA NA 54 62 NA NA 16 25 NA NA 6 6
(45,62) (52,71) (11,24) (17,34) (3,12) (3,13)
‘Homebake’ NA NA 18 24 NA NA 5 9 NA NA 1 1
heroin/ (12,25) (16,33) (3,11) (5,16)
morphine
Codeine NA NA 27 26 NA NA 21 16 NA NA 24 21
(20,35) (18,35) (15,29) (10,24) (18,32) (15,30)
Oxycodone NA NA 9 18* NA NA 3 5 NA NA 2 4
(5,15) (12,27) (1,8) (2,11)
Heroin 25 11 21 19 8 6 6 10 0 0 1 3
(17,35) (6,17) (15,29) (12,28) (4,15) (3,12) (3,12) (6,17)
Opium poppies NA NA 10 4 NA NA 5 3 NA NA 4 2
(6,17) (1,10) (2,10) (1,9)
Stimulants
Methylphenidate 43 46 37 40 21 26 23 22 13 15 19 19
(Ritalin) (33,53) (37,56) (29,46) (31,50) (15,30) (18,36) (17,31) (15,31) (8,21) (9,23) (13,26) (13,27)
Methamphetamine 40 44 47 50 100 97 100 100 21 23 13 13
(31,50) (35,53) (39,56) (40,60) (15,30) (16,32) (8,20) (8,20)
Ecstasy (MDMA) 30 22 18 13 50 51 47 41 100 100 100 100
(21,40) (15,31) (12,26) (7,21) (40,59) (42,61) (39,56) (32,51)
Cocaine 4 1 8 1 11 8 11 7 9 5 18 9
(6,18) (4,15) (6,17) (4,14) (5,15) (2,12) (13,26) (5,15)
Other drugs
Benzodiazepines 57 54 37 46 25 33 26 25 13 10 10 12
(47,67) (45,63) (29,45) (36,56) (18,34) (25,43) (19,34) (18,34) (8,20) (6,18) (6,16) (7,20)
Anti-depressants 8 9 19 18 5 14 14 12 3 5 7 6
(SSRIs) (4,16) (5,16) (13,27) (11,27) (2,11) (9,22) (9,21) (7,20) (1,9) (2,11) (4,13) (3,13)
Ketamine 5 6 1 7 6 13 8 10 10 11 9 20*
(3,13) (8,21) (4,14) (6,18) (6,17) (6,18) (5,15) (14,29)

*Statistically significant difference between 2009 and 2008 result at the P < 0.05 level.
Confidence intervals were not produced for rates of drug use that were extremely high or extremely low due to low numbers in either the ‘yes’ or ‘no’ category.
Pharmaceutical drug use by frequent illegal drug users
259

© 2011 Australasian Professional Society on Alcohol and other Drugs


260 C.Wilkins et al.

Table 3. Perceptions of availability and use of the four different opioid categories by combined frequent illegal drug users, 2009

Street/illicit Street/illicit ‘Homebake’ morphine/


morphine methadone heroin Heroin

2008 2009 2008 2009 2008 2009 2008 2009

Current availability
of opioids (%)
Number with (n = 110) (n = 108) (n = 86) (n = 78) (n = 27) (n = 45) (n = 38) (n = 40)
knowledge
Very easy [4] 40% 50% 32% 30% 19% 6% 20% 27%
Easy [3] 52% 40% 55% 47% 30% 43% 23% 22%
Difficult [2] 7% 9% 12% 21% 44% 43% 27% 22%
Very difficult [1] 1% 1% 1% 2% 7% 8% 30% 29%
Change in availability
of opioids (%)
Number with (n = 110) (n = 109) (n = 85) (n = 75) (n = 26) (n = 45) (n = 37) (n = 40)
knowledge
Easier [3] 13% 16% 7% 13% 11% 4% 17% 7%
Stable [2] 62% 60% 74% 67% 38% 46% 62% 55%
Fluctuates [2] 14% 7% 8% 5% 9% 9% 7% 7%
More difficult [1] 11% 17% 11% 14% 42% 41% 14% 30%
Number of people
using opioids (%)
Number with (n = 109) (n = 108) (n = 82) (n = 77) (n = 26) (n = 46) (n = 32) (n = 41)
knowledge
More [3] 22% 18% 31% 25% 32% 15% 22% 7%
Same [2] 59% 62% 65% 60% 46% 53% 45% 59%
Less [1] 19% 19% 4% 15%* 22% 31% 33% 34%

*Statistically significant difference between 2009 and 2008 result at the P < 0.05 level.

users had a prescription to use morphine in 2009 com- ecstasy (100%), alcohol (95%), cannabis (89%),
pared to 2008 (6% vs. 19%, P = 0.0362). tobacco (68%) and LSD (47%). Very low proportions
The drug types most commonly used by the frequent of the frequent ecstasy users reported using methadone
methamphetamine users in the past six months in 2009 and morphine over the four years of surveying
were methamphetamine (100%), cannabis (85%), (Table 2). Substantial minorities of the frequent ecstasy
tobacco (84%), alcohol (83%), crystal methamphet- users had used methylphenidate and ketamine in recent
amine (53%) and ecstasy (41%). Substantial minorities years. A higher proportion of the frequent ecstasy users
of the frequent methamphetamine users reported using had used ketamine in 2009 compared to 2006 (20% vs.
benzodiazepines, methylphenidate, morphine and 10%, P = 0.0334) and in 2009 compared to 2008 (20%
methadone over the past four years of surveying vs. 9%, P = 0.0142). Low proportions of the frequent
(Table 2). Most of the frequent methamphetamine ecstasy users had prescriptions for benzodiazepines
users who had used methadone had injected it (i.e. 70% (13% of those who had used them in the previous six
in 2006, 58% in 2007, 65% in 2008, 78% in 2009) and months) and methylphenidate (0%) in 2009.
about half who had used methylphenidate had also
injected it (i.e. 55% in 2006, 62% in 2007, 56% in
Current trends in availability and use of illicit opioids
2008, 54% in 2009). High proportions of the frequent
methamphetamine users reported having prescriptions High numbers of the frequent drug users reported they
for anti-depressants (85% of those who had used them had knowledge of ‘street/illicit morphine’ trends while
in the previous six months) and methadone (74%), but more modest numbers had knowledge of ‘heroin’ and
low proportions of frequent methamphetamine users ‘homebake’ morphine trends (Table 3). In 2009, 50% of
had prescriptions for oxycodone (0%), methylpheni- those with knowledge of street/illicit morphine
date (8%) and morphine (8%) in 2009. Only some of described the currently availability of street morphine as
the frequent methamphetamine users had prescriptions ‘very easy’ with a further 40% describing the availability
for codeine (42%) and benzodiazepines (34%) in 2009. of street morphine as ‘easy’. In contrast, 29% of those
The drug types most commonly used by the frequent who had knowledge of heroin described the current
ecstasy users in the past six months in 2009 were availability of heroin as ‘very difficult’ and a further 22%
© 2011 Australasian Professional Society on Alcohol and other Drugs
Pharmaceutical drug use by frequent illegal drug users 261

said the availability of heroin was ‘difficult’.There was a We found the injecting drug users had high levels of
statistically significant difference in the reported current use of pharmaceutical morphine rather than interna-
availability of the different opioids in 2009 (c2 = 40.03, tionally sourced heroin, supporting the understanding
d.f. = 3, P < 0.0001). Street/illicit morphine was consid- of the weakness of the heroin market in New Zealand.
ered to be currently more easily available than street/ A similar situation is found in the Northern Territory
illicit methadone (90% vs. 77%, P = 0.0440), heroin and Tasmania, which like New Zealand are geographi-
(90% vs. 49%, P < 0.0001) and ‘homebake’ heroin cally isolated and have smaller populations compared
(90% vs. 49%, P < 0.0001). Street/illicit methadone was to the larger states of Australia [19]. Oxycodone
also currently more available than heroin (77% vs. 49%, appears to be emerging as an opioid of abuse in New
P = 0.0072) and ‘homebake’ heroin (77% vs. 49%, Zealand and this appears to be directly related to its
P = 0.0072). There was also a statistically significant wider use following the granting of a government
difference in the reported change in availability of the subsidy [14]. The frequent injecting drug users also
different opioids in the past six months in 2009 had high levels of use and injection of methylpheni-
(c2 = 15.46, d.f. = 3, P = 0.0015). A higher proportion date. Methylphenidate is largely used to treat
of knowledgeable respondents thought ‘homebake’ Attention-Deficit Hyperactivity Disorder (ADHD) in
heroin had become ‘more difficult’ to obtain compared children and the number of prescriptions for meth-
to street/illicit morphine (41% vs. 17%, P = 0.0060) and ylphenidate in New Zealand has increased consider-
methadone (41% vs. 14%, P = 0.0054). A higher pro- ably over the past few decades in response to the
portion of those with knowledge of street methadone increase in the diagnoses of ADHD [6]. Methylpheni-
trends thought ‘less’ people were using street methadone date has similar effects to amphetamine among adult
in 2009 compared to 2008 (15% vs. 4%, P = 0.0227). users and there have been anecdotal reports in New
Zealand of drug users using methylphenidate as a
substitute for methamphetamine in areas where meth-
Discussion
amphetamine is less available [13]. Parents of children
This paper has examined the rate of pharmaceutical receiving methylphenidate and the children them-
drug use, levels of prescription use and levels of injec- selves have been reported to sell or trade methylpheni-
tion of pharmaceutical drugs by frequent injecting drug date to drug seekers in New Zealand [13]. A survey of
users, frequent methamphetamine users and frequent students in the United States found 23% of those
ecstasy users in New Zealand for the years 2006–2009. receiving prescription stimulants for ADHD (such as
An important contribution of our paper is to provide an methylphenidate) reported being approached to sell,
indication of the types of pharmaceutical drugs likely to give, or trade their prescription drugs [20].
be used in an extra-medical manner by the newly The frequent methamphetamine users had also
emerging groups of frequent drug users in New used methadone and morphine in an extra-medical
Zealand (i.e. frequent methamphetamine users and fre- manner, as well as methylphenidate and benzodiaz-
quent ecstasy users). epines. The frequent ecstasy users had low levels of
High proportions of the frequent injecting drug users use of morphine, methadone and ‘homebake’ mor-
had a prescription to use methadone but a high pro- phine use but sizable minorities were involved in the
portion had also injected methadone. The injection of extra-medical use of codeine, methylphenidate and
methadone is associated with increased health prob- benzodiazepines. The differences in the extra-medical
lems due to the difficulties of injecting methadone in a use of pharmaceuticals between the frequent drug
highly diluted form [18]. There are many benefits from user groups suggest that effective control strategies for
having injecting drug users enrolled in methadone each group may differ. For example, regulations
maintenance programmes and these benefits have been restricting the non-prescription retail sale of codeine
found to increase with the length of time the patient is products were tightening up in New Zealand in late
on the programme [18]. These findings suggests that 2010 (i.e. requiring codeine-based pain killers to be
the focus in these circumstances should be on keeping sold by qualified pharmacists only and to be stored
patients in methadone programmes rather than taking a behind the counter of pharmacies) and these moves
punitive approach to continued injection of methadone may be sufficient to discourage codeine use by fre-
[18]. It has been suggested that an open and empathetic quent ecstasy users who are largely occasional illegal
relationship between the patient and clinician, as well as drug users [see 21]. Frequent methamphetamine
the provision of harm minimisation information con- users in New Zealand appear to largely use meth-
cerning safe injection, can work toward reducing the ylphenidate as a substitute for methamphetamine in
underlying reasons for continued injection of metha- circumstances where the availability of methamphet-
done and also reduce the immediate health risks of such amine is difficult [13]. Consequently, steps to impose
behaviour [18]. greater controls over methylphenidate may be fairly
© 2011 Australasian Professional Society on Alcohol and other Drugs
262 C.Wilkins et al.

effective by making it more difficult to obtain relative


Acknowledgements
to methamphetamine. However, if tighter controls of
methylphenidate push more people back to using We would like to thank the anonymous referees for a
methamphetamine this may not result in better out- number of valuable comments and suggestions on our
comes for users and their dependents. paper. The IDMS is conducted as part of the New
Injecting drug users are likely to be the most difficult Zealand National Drug Policy. We gratefully acknowl-
to deter due to a combination of opioid dependency edge the support of a number of government agencies
and level of experience with pharmaceutical diversion including the New Zealand Police, New Zealand Min-
strategies. Efforts may be better focused on encourag- istry of Health and New Zealand Customs Service. We
ing injecting drug users to enter therapeutic relation- would like to thank researchers at the National Drug
ships where harm minimisation information can be and Alcohol Research Centre (NDARC) for sharing
conveyed and underlying issues related to drug use materials with us during the early development of the
explored. It might also be worth exploring whether the IDMS. We also acknowledge the New Zealand Needle
diversion of methadone was occurring because there Exchange who assisted us with the recruitment of fre-
were real or perceived barriers to entering drug treat- quent drug users for the project.
ment and receiving methadone as part of a legitimate
treatment programme. References
We acknowledge a number of limitations to our [1] International Narcotics Control Board. Report of the Inter-
study. Firstly, our frequent drug user sample is a pur- national Narcotics Control Board for 2006. Vienna: United
posive one and hence not representative of frequent Nations, 2007.
drug users in the site locations. Secondly, our sample is [2] Inciardi J, Surratt H, Kurtz S, Ciciero T. Mechanisms of
limited to the three main urban centres of New prescription drug diversion among drug-involved club and
street based populations. Pain Med 2007;8(2):171–83.
Zealand; frequent drug users in rural areas may have [3] St George B, Emmanuel J, Middleton K. Overseas-based
different patterns of pharmaceutical drug use. Thirdly, online pharmacies: a source of supply for illicit drug users?
our one-off questions concerning whether a drug user Med J Aust 2004;180(3):118–9.
had a ‘prescription in their own name’ or had injected a [4] Carlet D. Unhinged: the trouble with psychiatry—a doctor’s
pharmaceutical in the previous six months were not revelations about a profession in crisis. NewYork: Free Press,
2010.
detailed enough to provide precise estimates of the [5] Cicero T, Inciardi J, Munoz A. Trends in abuse of OxyCon-
extent of extra-medical use. Those with a legitimate tin® and other opioid analgesics in the United States: 2002–
prescription to use a pharmaceutical drug may still use 2004. J Pain 2005;6:662–72.
pharmaceuticals in an extra-medical manner and it is [6] Newbold G. Crime in New Zealand. Palmerston North:
not clear from our injection question how much of the Dunmore Press, 2000.
[7] New Zealand Customs Service. Review of Customs Drug
pharmaceutical drug was injected and hence used Enforcement Strategies 2002. Project Horizon Outcome
extra-medically. Report. Wellington, New Zealand Customs Service, 2002.
Our findings broadly support recommendations to [8] Adamson S, Sellman D. The pattern of intravenous drug
tighten the control of prescription drug use in New use and associated criminal activity in patients on a metha-
Zealand [13]. Extra-medical use of pharmaceuticals done waiting list. Drug Alcohol Rev 1998;17:159–66.
[9] Sheridan J, Butler R. Prescription drug misuse in New
extended beyond injecting drug users to include fre- Zealand: Challenges for primary health care professionals.
quent methamphetamine users and even frequent Research in Social and Administrative Pharmacy 2010;
ecstasy users. Increasing control over pharmaceutical Available online 16 October 2010: doi:10.1016/
drugs involves a delicate balance between reducing the j.sapharm.2010.06.005.
extra-medical use of pharmaceuticals while at the [10] Wilkins C, Bhatta K, Casswell S. The emergence of
amphetamine use in New Zealand: findings from the 1998
same time not denying access to pharmaceuticals to and 2001 national drug surveys. N Z Med J 2002;115
those with legitimate medical needs [13–15,22]. Also, (1166):256–63.
as noted in our discussion, there is a risk that tighter [11] Wilkins C, Bhatta K, Pledger M, Casswell S. Ecstasy use in
restrictions of pharmaceuticals will drive some users New Zealand: findings from the 1998 and 2001 National
to obtain similar drugs from the illegal drugs market Drug Surveys. N Z Med J 2003;116:383–93.
[12] Wilkins C, Sweetsur P. Trends in population drug use in
or may drive them away from potentially helpful New Zealand: Findings from national household surveying
therapeutic relationships. Policy changes which seek to of drug use in 1998, 2001, 2003 and 2006. N Z Med J
tighten the supply of pharmaceuticals need to con- 2008;121:61–71.
sider these unintended consequences. The differences [13] Sheridan J, Butler R. Prescription Drug Misuse: Issues for
found in the patterns of pharmaceutical drug use Primary Care – Final Report of Findings. Auckland: School
of Pharmacy, University of Auckland, 2008.
between the different frequent drug user groups [14] Babor T, Caulkins J, Edwards G, Fischer B, Foxcroft D,
suggest that a ‘one size fits all’ response will not be Humphreys K, et al. Drug Policy and the Public Good.
effective for all types of drug users. Oxford: Oxford University Press, 2010.

© 2011 Australasian Professional Society on Alcohol and other Drugs


Pharmaceutical drug use by frequent illegal drug users 263

[15] Royal Australasian College of Physicians. Chronic Non- National Drug and Alcohol Research Centre, University of
malignant Pain: Improving Management and Prevention of New South Wales, 2009.
Problematic Opioid Use. Sydney, 2008. [20] McCabe S, Teter C, Boyd C, Guthrie S. Prevalence and
[16] Biernacki P, Waldorf D. Snowball sampling: problems and correlates of illicit methylphenidate use among 8th, 10th,
techniques of chain referral sampling. Sociol Methods Res and 12th grade students in the United States, 2001. J
1981;10:141–63. Adolesc Health 2004;35:501–4.
[17] Watters J, Biernacki P. Targeted sampling: options for the [21] Wilkins C, Griffiths R, Sweetsur P. Recent Trends in Illegal
study of hidden populations. Soc Probs 1989;36:416–30. Drug Use in New Zealand, 2006–2009: Findings from the
[18] Judson G, Bird R, O’Connor P, Bevin T, Loan R, Schroder 2006, 2007, 2008 and 2009 Illicit Drug Monitoring System
M, et al. Drug injecting in patients in New Zealand Metha- (IDMS). Auckland: Social and Health Outcomes Research
done Maintenance Treatment programs: An anonymous and Evaluation, School of Public Health, Massey Univer-
survey. Drug Alcohol Rev 2010;29(1):41–6. sity, 2010.
[19] Stafford J, Sindicich N, Burns L. Australian Drug Trends [22] United Nations Office on Drugs and Crime (UNODC).
2008 – Findings from the Illicit Drug Reporting System 2010 World Drug Report. Vienna: UNODC, 2010.
(IDRS). Australian Drug Trends Series No. 19. Sydney:

© 2011 Australasian Professional Society on Alcohol and other Drugs


Copyright of Drug & Alcohol Review is the property of Wiley-Blackwell and its content may not be copied or
emailed to multiple sites or posted to a listserv without the copyright holder's express written permission.
However, users may print, download, or email articles for individual use.

Das könnte Ihnen auch gefallen