Jourttttl oj ( tlntnt l)c'veloltttt('ltl & l(t,.

tt,ru r lt )t tt t4

VAGINAL 'I'L]NIOITS [N IJI I'UIIUS

G.N.Purohitr. Arvind Shurnlu:" i\l,Guur-- rrncl Srrnita R:rni{

Department of Aninutl Ilt protlrre tron. . ivrlrr.t.,.rloIr, rrrrrl ( )lrstclt.lcs
College clf Vetr'r'inltr'\/ ilrrtl ,,\nnnill St.rr.rrr'r'. IJik;rrrcr tll;tt.)- ll4 (X)l

n IJS',I't{n C'!

Bitches of various breeds pre seiitcd rvrtlt r't ltistorv ol'lurcrnorr'lurtic vlgirrirl clischargc and or growth
in the va-eina(n=18) w vestigated. Ten of thcsc bitchcs wcrc rn dil'l'crcnt procstrual stagcs whercas,
eight bitches-showed thS p,fdifferent !),pps which were,diagnosed ro bc transmissible venereal
Iumor (TVT. n=5) and ma (n-3). Bitchcs witlr l'VT u,crc trcalcrl wirh vincristinc sulfarc 0.025 ms/
kg ing.ra.uenous or SC. weekly 'for 3-4 rvccks witlr un Lrlrcvcltl'ul rcc6r,cpy. I;it1.9111s wcrc rcnrevcd
" . ,.
... .,.. , sur,sically.

\/u*tnalbleedingisanphysiologicai eventfor included German Shepherd, Pomeranian,

Y bitchesinproestmshowever,manyowners Doberrrarl. Great Dane, Labrador and Non-
'
may be frightened and present their bitches to Descript. Bitches were examined by speculum
., .:the clinician. for examination and therapy. A and those showing growth externally were
prolonged bieeding horyever. warranrs a visualiy inspected. Swabs were made from
:: thorough examinaliron as Iit may occur because anterior vagina from bitches that had no growths
r -:o-f-growths, -uierine problems, problems
of ancl c)/toiogical examination was done to give
vestibulum or.trrinary biadder and growths. advice on breeding and/or to keep the bitches
Vaginai rumors are detected in the bitch incioors to owners that did not inrend breeding
significantly more often than ovarian or uterine and had brought bitches only bec4use of fear of
tumors with qJost. of them being benign like vaginal bleeding. Transmissible Venereal Tumor
leiomyomas, ,fibromas and others (Dreier, (TVT) was diagnosed by typical cauliflower Iike
I 998). Bitches:invdstigated during rhe presenr or nodular appearance and impression smears
study had growths which were treated by revealing typical rbund cells.(Fig.l).
;chemotherapy or surgery. Chemotherapy of TVT comprised of
.' 1-:;t
i: ..' ". '
adnrinistration of vincristine sulfate @ 0.025 mgl
, IVlaterials and methods, kg B. wt. IV or SC, weekly for 3-4 weeks.
'
Sur-qical removal, of tumors was done by
Bitches pres( ,dtt"o, of
hae mo nB1. episiotomy under general anaesthesia using
*-*in 4 ai,ggh$rge{n = I 8 ) be t w e e n
,, u
ketamine .and, xylazi.n employing standard
January 2003 ,lg Apiit i'O0Sio
UJ lg,April2QO5 ro the vererinary
veterinary
.obitetrics an
techniques( ,Fibromaswere
3nd" SVnaec;glogy. eurdoor were diagnosed by histo-pathological examinarion
r',:.iiicluded in thiS study.
1y The"breeds of bitches
and appearance of fibrous bands (Fig. 2).

lAssisrant ')
-Vcterinary Oificer, Madhu Farms, Chomu.
" 3Arriron, Gynaecologisr.
Professor
LRS. Vallabhn agar. Ud ai pu r. "Assistant Profcssor. Deptr. of Vety. Pathology
,''
36

l,

'l
- -Jiiffi-oJCrri*'Dirrlop^enr & Researcit

Fig. l: Microphotograph of a smear,ftqtl q,E3"sg 9f Fig. 2: N{iilophoto-qraph of a fibroma removed from

TVT showing round cells.
bitch tebrous bands are visible

Fig.3: Photograph of a bitch showing a tumor (TVT;. Fi-e. -l: Photoeraph of a bitch shorvin-e a small nodule
of TVT in a Pomeranian bitch.

Fig. 5: Photograph of Porttc'ritrtilttt [ritch slrorr ittr rt t]brtrtttlt.

 Journal of Canine Dbvelop.ntent & fle;;ectrt.lt J0t)J
: '"
.;.,'j

Results and discussion

l;rbrorlrs rc;l,r'(cd rrr tlrrs study rcspondecl wcll
Io sr-ir-eicai excision. studies by Thacher and
lJ.lrrlict. i ()g.l l.t.l't, l)t.cvi.usly .showrt thltr
L'.\ecl)r lor' !'\z'l'nr()sr. tLrrror'.s in bitcltcs arc ()l'
srrrotlrli nrrrscle- or fihrou.s tissue origin
(lci,r'r))/or)u. t'i[lr'orr,) which r.cspond well tcr
surgrcai excision.

It was concludccl thut bitchcs with prolonged

week but it died due to eitreme weakness.
Surgical ..rno'u"l of fibromas showed uneventful
recoverv
Vaginal and vestibular masses have been
known
to ber neoplasia,'prbiapse, clitoral enlargement.
urerine prolapsg. abscessation and haematoma
(Manothaiudom and Johnsron, l99l The
). mosr
j , ,. .,., ,,colTlTon clinicai sign with vaginal or vui.var
'.,
'irsrnal bleedin-e o. discharge must be examined
thorou_eirly for- rhc like ly presence of tumors.
Reflerences
Boscos. CM and Vcrvcr.iclis. HN.(2004). Canine TVT:
Clinical findings, diagnosis and treatment.
Sci.Proc WSVA-FECAVA_HVMS World
Con_eress. Rhodes. Greece. (2):7 5g_7 6l .
Brocie;,. R.S and Roszel, J,F ( 1967).Neoplasms of
the
canlne uterus. vagina and vulva. A clinico_
pathologic survey of 90
i.Amer.Vet.Med.Assoc. l5l:1294.
cases

. , "',',. ,ngoplasia_._is
' ':
,vulvar disch4rge gI sudden
'.; :a i :':q.,ii.oa?^n^^ Cal'er cA. Leifer CE, McEwen EG.(r gg2).vincristine
; ,,;'
' ,' , "i.'.l..
apptqrance
.
":1'' -- - r
of a mas-s. from the vulva and occLrs
^"^- ,r
for the treatment of Transmissible Venereal
,' ' |:.fmolly iil qL$, ?gb rsexually intact dogs Tumor in the dog. J Amer. Vet. Med. Assoc.
, , ( r nacner and B'radleJ, j.l9.g-3). ,Neoplasia of l8l(2):163-t6+.
Chaudhary,C and Rao, tvt.R. K( I 9g2). Cerrain canine
',':,1s^'l:,1i1 :'rY" *llrpifi!3.*;, ;; neoplasmb encounrered in Andhra pradesh.
Indian.Ver.J, 59: I ilO- t OZ.
Dreier, H.K.( 1998)Va_einal discharge. In: Gorman,N.T.
Ecj, Canine Medicine and Therapeutics.
Blackwell Science U.K.
Gandotra,V.K.. Chauhan,F.S and Sharma,R.D( I 993).
Occurrence of canine transmissible venereal
tumor anci evaluation of two treatments.
Indian Ver.J.70: 8 54-g5i .
Manothaiudom,K and Johnsron, S.D( l99l ). Clinical
(Tell a er al., 2004). Most of the birches approach ro vaginal/vestibular masses in the
lresponded fivourably to the rrearment bitch. Ver. Clin. North Amer. Small Anim.
although
they showed varying degrees of gasrointestirial Prac.2l(3):509-21.
Tc'lla.M.A., Ajala. O.O anci 'Iaiwo. V.O(2004).Complere
problems including vomiting, similar to previous regrcssion of transmissible venereal
repons( Boscos and Ververidis. 2004: Calver rumor(TVT) in Ni_eerian mongrel dogs wirh
et al.. 1982). Subcutaneous injections of vincrisrine sulfate chemotherapy.
vincristine were given to bitches with small Afr.J.B io.Med.Rcs.7(3): I 33- I 39.
sized Thacher'. C and Bradley. R.L.( l9g3). Vulvar ancl, vaginal
TVT but due to intense local reaction. rulnors in thc do-s: a rctrospective study.
intravenous route wa.s opted in subsequent Arrr. Vcr. Mcd. Assoc. lti3(6): 690_92.
J

'
[reatmen6.'

38