Beruflich Dokumente
Kultur Dokumente
11/03/2019
Srivatsa Thumurikota
Karan Jagadeesh Uppin
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Table of Contents
Introduction 2
Case Write-up Question 2
Answer 1 3
Answer 2 20
Answer 3 + Case Study 34
Final Conclusion 72
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Introduction
The following document is a case study on the b iopharmaceutical company,
Biocon India. Different strategies for the expansion of the company are being
discussed in detail and a final solution is being proposed.
Study Questions
1. What are the advantages and disadvantages of starting and operating a
pharmaceutical firm in India?
2. Is the Indian CRO market attractive?
3. What is the best way for Biocon India Group to expand?
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Answer 1
What we already know from the paper-
Clinical research in India was beginning to take off, and was forecast to explode
during the next decade. Contract research organizations (CROs) were emerging as
the key players in this market.Lotus Labs, for instance, was growing at a rate of
100% per year, and one study predicted that Indian CROs would grow from 0.7% of
the global market in 2002 to 20% in 2010. Within India, CROs based in Bangalore
accounted for 2% to 3% of the total CRO activity in India, which was estimated at
Rs. 250 crores in 2000, and were expected to continue to grow over the next few
years.
The Indian pharmaceutical industry had been shaped to a great extent by
economic policies since independence in 1947. Initially, pharmaceutical
multinational corporations (MNCs) from Europe and the United States dominated
the local market. In the 1960s, India’s government established local bulk drug
manufacturers Hindustan Antibiotics Ltd. and India Drug and Pharmaceuticals
Ltd. to compete with the MNCs’ overseas bulk-drug operations for supplying local
formulation plants. In 1970, the government passed two regulations that affected
the pharmaceuticals industry: the India Patent Act (IPA) and the Drug Price
Control Order (DPCO). The India Patent Act prohibited “product patents for any
invention intended for use or capable of being used as a food, medicine, or drug or
relating to substances prepared or produced by chemical processes.” As a result,
any drug on the market could be reproduced without retribution. The Drug Price
Control Order gave the Indian government the authority to set prices for drugs
sold on the local market.
Starting in its earliest days, the industry experienced phenomenal growth. A
combined bulk drug and formulations output of 168 Rs. (crore) in 1965 grew to
19,737 Rs. crore 35 years later, an annual growth rate of 15%. Roughly two-thirds of
the output stayed in the domestic market, which by the year 2001 was also
growing at 15% annually. The remaining one-third – 6,631 Rs. crore – went to the
export market, which had a 21% growth rate. By the beginning of the 21st century,
over 20,000 pharmaceutical companies were operating in India.
What we found through various sources that helped us answer this
question:
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Generics Drug Industry in the U.S. -
What is a generic drug?
A generic drug is a prescription drug which is not manufactured by the originator
of the product; the molecule is off patent and available from multiple sources, and
the product is known by the chemical name, not a trade name.
According to a recent Bank of America report, pharmaceuticals are the
fastest-growing component of health care costs. The U.S. currently spends
approximately $150 billion on prescription drugs and some industry sources
project this number will reach $300 billion by 2010, equivalent to annual growth of
approximately 9%. Due to this increase in cost, managed care and other insurance
providers are seeking to control pharmaceutical expenses through generic
substitution. With continued pressure on cost, the aging demographics of the U.S.
and the continuing rise in co-pay hurdles, the generic drug industry is expected
to grow in coming years.
Indian Pharmaceutical Industries-
Many leading Indian pharmaceutical companies relied heavily on the domestic
market until the mid-1990s. Most recently many Indian pharmaceutical
companies have taken advantage of the lucrative global generics market.
Within this market, one of the stronger forces is the economically competitive
generic drug companies from China and India. India especially is well positioned
in this industry with their product development skills through advance chemistry
capabilities and low-cost manufacturing.
In order for the smaller, new Indian Pharmaceutical companies to take advantage
of this giant market, there are various ways of entering and capturing the market
share. This market is highly competitive as these Indian companies are not only
fighting with the domestic giants who are currently active in the generic drugs
industry, but also with the multinational corporations and many American and
European specialty pharmaceutical companies and generics drug companies in
this space. In order for the smaller Indian Pharmaceutical companies to survive,
it is vital to look for longer term gain instead of focusing on shorter term outlook.
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Some steps are-
1) Long term planning- s maller drug companies may be wise to invest in
having a longer time horizon rather than focusing on the earlier patent
expirations. They need to focus its resources in one or two top priority
drugs rather than broadening their scope with their limited resources
2) Partner up with larger Indian Companies - The larger Indian drug
companies, i.e. Ranbaxy, Dr. Reddy, Cipla, can help the smaller companies
by offering their distribution channels and the smaller pharmaceutical
companies can offer their technology, their current research, etc. Of course,
this is under the assumption that Ranbaxy and Dr. Reddy and likes are
willing to partner up with the smaller Indian companies. If the smaller
companies have a special product to offer, this might be more feasible.
3) Partner with larger U.S. or European drug companies – If the partnerships
with the domestic companies are difficult due to reluctance of the larger
Indian companies, it might be an attractive option to seek international
partnership. Many U.S. and European drug companies, especially mid-size
companies, would welcome the opportunity to gain exposure to and partner
with Indian pharmaceutical companies.
Let’s get down to numbers,facts and models -
India stands among the top 5 pharmaceutical markets in the world. For the past
few years, the awareness regarding health and hygiene has increased, which has
led to increase in the sale of pharmaceutical products in India. The total revenue
generated through exports by pharmaceutical companies in India in the last
financial year was more than $20 Billion and Table 1 captures the region wise
exports done in 2015 and 2016. Indian pharmaceutical industry comprises of 250
to 300 large companies which account for 70% of products in the market with
representation of top 10 firm’s contribution of 30%.
According to IBEF, the domestic Indian pharmaceutical industry is estimated to
be $ 26 billion in 2014 growing at nearly 20% and is expected to reach nearly $50
billion in 2020. It is evident that a lot of internal factors are responsible for the
growing Indian pharmaceutical industry. There are more than 200 companies
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medicines for the largest population in the world which adds to the prevailing
competition on the domestic front. To explore further opportunities of growth, the
Indian pharma players, particularly the large ones have set up their subsidiary
companies, regional offices or taken over local companies in other geographies
and many have even set up their manufacturing plants in developed nations too.
Indian government has rolled out many industry friendly policies to encourage
the innovation and manufacturing to make pharma one of the most sustainable
industry which can help in building country’s economy.
Ministry of commerce and industry, Govt. of India has set up P
harmexcil
(Pharmaceuticals export promotion council of India) to promote and support
small, medium and large Indian pharma companies focusing on exports.
Pharmexcil supports in terms of organizing the buyer seller meetings in India and
overseas, financial support to set up exhibitions to showcase the products and
technologies, reimbursement of part of the regulatory related expenses.
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Pharmexcil also maintains excellent global data of traders, agents, distributors,
marketers, manufacturers, regulators in pharma industry
Having known for knowledge driven sector, it has also contributed to Indian
economy by generating hugs employment in all levels and contributing to Indian
economy. Due to the global presence, pharma sector has helped to strengthen
brand India along with Information technology sector. This is a recipe for young
pharma entrepreneurs.
Economies of scale in Indian Pharma business -
Economies of scale capture the effect of increased production on the average cost
of production of a firm. To get an idea about the extent of the scale economies , An
Overview of the Indian Pharmaceutical Sector Indian pharmaceutical industry the
average cost of production is plotted against the sales volume for a sample of 280
firms for the year 2002. In the presence of scale economies, the average cost of
production exhibits a non linear relationship with the level of output. Ideally, it
initially falls and then rises exhibiting a U–shaped relationship. FG 2.1
The vertical axis measures the average cost of production and the horizontal axis
the total revenue of the firms. The diagram indicates the presence of scale
economies for the industry within a range of about Rs. 10 crore of sales volume,
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beyond which the average cost curve takes a flat shape. This indicates the
industry cost curve to be L shaped which implies that there are no significant
diseconomies of scale for large sized firms. To get a clear idea about the
approximate size of the Minimum Efficient Scale (MES) in the industry the loess
fit is also done separately for firm size up to the sales volume of Rs. 30 crore. This
is illustrated in FG. 2.2. F
igure 2.2 indicates the presence of scale economies at a
Minimum Efficient Scale size (M.E.S) of Rs. 8 crore.
Capital Intensity of the Indian Pharmaceutical Sector-
To understand the extent of capital intensity in the Indian pharmaceutical
industry a cross comparison of capital intensity of pharmaceutical firms reported
in the CMIE database is made with the total manufacturing and chemical firms.
Table 2.4 summarizes the mean capital intensity of the pharmaceutical, chemical
and manufacturing sectors. Table 2.4 suggests that the trend in capital intensity
is rising after 1995. On an average, the capital to sales ratio is around 55 % for the
pharmaceutical sector. This implies that as the market size of the pharmaceutical
industry is increasing due to growth in this sector by about 16 % in recent years,
the capital investment is also rising over the years. However, on the whole the
sector is less capital intensive compared to the manufacturing sector.
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Labor Intensity in the Pharmaceutical Sector -
After measuring capital intensity, the labor intensity in the Indian
pharmaceutical sector is also computed and compared with the chemical and the
manufacturing sector to get an idea about the employment potential of the sector.
Table 2.5 summarizes the mean labor intensity for the pharmaceutical, chemical
and manufacturing sectors
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It is observed from the figures in Table 2.6( below) that the pharmaceutical sector
(on an average) spends more on wages and salaries compared to the chemical and
manufacturing sectors. However, there has been a marginal fall in the potential to
absorb labor in the pharmaceutical sector in the early 1990s though it again
picked up from 1997. Since the industry is growing at an annual rate of 16%, it can
be inferred that the potential to absorb labor and generate employment in the
pharmaceutical sector is also rising over the years.
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Do you need a R/D department? -
The performance of firms on the basis of their R&D, marketing and export related
activities as well as size are compared. Thus, firms that jointly capture 75% of the
sales volume of the industry are classified as large sized firms and the rest as
small-sized firms.(Table 2.6).
It is evident from the figures in the Table that large sized firms have earned
higher profit and also have higher productivity compared to small firms. In the
pharmaceutical industry, the benefits of higher profitability accrue to large sized
firms not because of economies of scale in production but because of other
factors like ability to undertake R&D or do more of marketing activity at large
scale
It is noticed from T able 2.7 that, on an average, firms with R&D units have earned
higher profit compared to firms without any R&D unit. The productivity difference
also reveals similar trends. This indicates that investment in R&D is an effective
action for firms to perform better.
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Real R&D expenditure (Crores and dollars) in the Indian pharmaceutical sector
(Source: Computed from the Bulk Drug Association of India) :-
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Certain other numbers that help you set up your pharma industry-
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SWOT Analysis -
There are many influential factors that could impact the pharma industry in
future. Some of them are intrinsic in nature and some are extrinsic.
In spite of pharma industry’s success and growth, Indian pharma industry
continues to face challenges globally in the area innovation, quality issues, supply
delays, marketing challenges, adoption of latest digital technologies and many
more.
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Area of digital opportunity - for optimization of resources-
There are four main areas where digital developments will drive value for pharma
companies, building on what we see as the key components of digital success—an
ability to deliver more personalized patient care, engage more fully with
physicians and patients, use data to drive superior insight and decision making,
and transform business processes to provide real-time responsiveness.
Companies do not have to become leaders in all four areas across the
enterprise—some will deliver more value than others in relation to any given
disease, depending on market dynamics and their portfolio.
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From the above research we can conclude the following -
There are advantages which are -
● Opportunity for foreign companies : Foreign companies heavily rely
on indian CRO’S to invest in due to it’s very low cost activities.
● Ease of conducting clinical trials : Clinical trials services, in
particular, were emerging as prime targets for outsourcing to India.
Clinical trials represented the most expensive part of the drug
development chain. India has a huge population and the ability to
conduct clinical trials is easier due to people emerging from diverse
backgrounds etc. The trial subject is also mostly always willing to
take part.
● Advent of patents : In the 1970s, the Indian government implemented
the acts Drug Price Control Order (DPCO) and India Patent Act (IPA).
These provided a huge boost to the manufacturing of generic drugs
in India, to the extent that India holds 20% of the global market share
in generic drugs.
● Large established Pharmaceutical market in India: Starting in its
earliest days, the industry experienced phenomenal growth. A
combined bulk drug and formulations output of 168 Rs. (crores) in
1965 grew to 19,737 Rs. crore 35 years later, an annual growth rate of
15%. Roughly two-thirds of the output stayed in the domestic market,
which by the year 2001 was also growing at 15% annually. The
remaining one-third – 6,631 Rs. crore – went to the export market,
which had a 21% growth rate. It now has over 20,000 companies
operating and to set one up and not succeed with the already trial
and tested methodology is not possible.
● Very well Educated workers : India had a large pool of
English-speaking scientists and professionals who were
well-educated and well-trained. They were also cheap: a Ph.D.’s
salary in India averaged approximately $15,000, while the equivalent
in the United States was closer to $100,000. So higher chance of job
creation in the pharma sector.
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T
he disadvantages on the other side which are:
● Market instability : Due to the existence of more than 20,000 pharma based
companies in the country it is difficult to particularly stand out on top.
● Effect of Foreign companies : Many MNC’s entering India due large
availability of workforce, labour and lower investment costs for them
decreases the chance of the company to expand or advance as it is often
taken over by the larger MNC’s
● Effect of patent laws: According to DPCO , the price of the drugs sold
domestically was given by the indian government and this affects the
production company as even though it incurrs losses it cannot change the
price of the drug to breakeven or gain profits.
● Effect of conducting clinical trials : Significant proportion of the population
is uneducated, holding clinical trials on such people may lead to many
ethical questions. Any trial subject can falsely accuse the company and its
motives behind the tests.They can create an ugly image and threaten to sue
the company. In the highly competitive Indian pharmaceutical industry
and the effects of social media, image tarnishing can lead the company to
incur significant losses.
P.S Some actual procedures to set up your pharma business are here :
http://www.fossilremedies.com/start-pharmaceutical-manufacturing-unit-india/
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Answer 2
A contract research organization (CRO) provides support to the pharmaceutical,
biotechnology, and medical device industries for specific services on a contract
basis. The services may be clinical research, product development such as drug
development or process development such as bio analytical assay development.
The sector for CRO in India is estimated to generate revenues worth $1973.82
million as compared to $1000 million in 2016, the industry is also expected to
attain a CAGR of 12.00 per cent in the forecast period.
India is emerging as a top destination for contract research organizations for the
following reasons:
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4) Increased investment from foreign entities as well as local players
either individually or in collaboration-
Increasingly the country of choice for outsourcing of pharmaceutical products,
whether finished or intermediate, is India.
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For example, during summers, temperature may reach up to 50C in some parts of
Rajasthan and western Gujarat, while at the same time the temperature may be
just around 20C in Jammu and Kashmir. Thus allowing stability studies to be
performed with ease in one destination.
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Due to the above stated reasons, the CRO sector in the Indian market is
flourishing.
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For example, Lotus labs was growing at a rate of 100% per year.
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1) Indian CROs were focused primarily on serving the need for BE/BA studies in
the market, which constituted the low-to-medium segment of the value chain.
2) Meanwhile foreign CROs, such as Quintiles, and the in-house data management
centers of big pharmaceutical companies, such as GlaxoSmithKline and Pfizer,
were focusing their efforts on serving higher-value needs of the market,
particularly data management and Phase III clinical trials.
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As observed from the Pie Chart given below, Phase lll counts for 35% of the CRO
market share.
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2) The market is small, the players have increased with similar and relatively
similar services. As the market gets more competitive, the share of each player
comes down. Below are some of the key players in the Indian CRO market.
3) The market constraints are growing concern for security especially data
security and patient security, lack of collaboration between universities and
industry etc. The compromises done by some Indian CROs on ethical and
technical standards are the greatest market threat. Pharmaceutical and biologics
firms need to select reliable partners who will add value to their medical
research.
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As observed from the above Pie chart, the selection criteria for Pharmaceutical
companies while selecting CROs is the reputation and the quality of the service
they provide. Hence some pharmaceutical MNCs are wary of outsourcing such
critical and sensitive tasks to a largely unproven Indian industry.
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Clinigene’s main aim was to offer a broad range of clinical trial services,
recognizing that drug development could span two different areas that
consequently required different types of clinical studies. Generally, generic drugs
required bio-equivalence and bio-availability (BE/BA) clinical studies to prove
that the generic drug worked as well as the off-patent original drug. But for new
drugs, much more elaborate clinical trials had to be conducted.
In the few years since its launch, Clinigene had focused not on organizing trials
but on clinical lab services, BE/BA studies, and partnership coordination with
hospitals. This lead to a dilemma on how it’s capabilities would work for Biocon
as a whole in the long run.
➔ There are a couple of solutions to this problem that we would like to share
by putting ourselves in Kiran’s shoes. The problem diverges into three
‘paths’ as we would like to call it each with its own fortunes and
misfortunes.
As of events in the paper, Biocon India was still several years away from
developing its own drug molecules. So till it develops its own drug formulation, it
could lend its hand in helping various organizations (as a CRO)in conducting
studies and setting up their game in clinical trials. This would in turn help Biocon
for when it does develop that drug molecule and still keep making profits which
are small.
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➔ Any company which enters into the market with its new product or just
expands in general has to perform market analysis which is a crucial
element in determining A-Z about the market conditions, customers,
competitors, suppliers etc.
● SWOT analysis is done every year to analyse the company’s growth.
● PEST analysis can be done to find out the surrounding environment which
govern the market
● Igor Ansoff’s growth matrix can be used to determine the growth of the
product via penetration and development.
● BCG matrix can also be used to evaluate the strategic position of the
business brand portfolio and its potential.
● Porter’s five forces model.
➔ There are also certain growth strategies a company considers while
expanding (determined by the above analyses). These are :-
1) Vertical Integration
2) Concentration
3) Diversification
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Path 1: The Vertical Integration approach
➔ Vertical integration is when a company controls more than one stage of the
supply chain. That's the process businesses use to turn raw material into a
product and get it to the consumer. There are four phases of the supply
chain: c
ommodities, manufacturing, distribution, and retail. A company
vertically integrates when it controls two or more of these stages.
Backward integration is when customer enters into your domain and
Forward Integration is when supplier enters your domain.
Now back to the case study,
Clinigene being a part of Biocon India Group can step it’s domain of activities and
can match up the demands in the global markets by providing complete clinical
trials.
This further leads to investment of capital and resources like time to make sure
that Clinigene reaches that stage.
“Clinigene’s current capabilities positioned it in the low- to medium-value
segment of the value chain. Moving up the value chain might be more profitable
in the long run but would entail significant costs, both financial and cultural.”
The pharmaceutical industry is moving at a fast rate and Clinigene has still been
doing small studies and finding out developmental procedures rather than
stepping out of its shadow to bring in real value to the company.
This transition however could affect the core values and cultures of the company
and how they run things. But at the same time sabotaging those ethics so that
Clinigene can make heavy profits in this rapid growing sector feels like the
correct thing for them to do.
Clinigene was already set up and was not adhering to its aim. What Biocon should
do is shift focus from conducting BE/BA studies to tasks and activities that focus
mainly on clinical trials. If clinigene does succeed in fulfilling its aim, then it does
truly add value to the company as it will be ready for phase 3 and phase 4 trials
and these are the opportunities that have to be capitalized upon. With that said,
Biocon will then be a fully vertical integrated company with having its own R/D
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unit, its own clinical trials unit and its own manufacturing unit. Competitors like
GSK who lead the market in data management and phase 3 trials are threats to
the growth of Clinigene and they have to be looked out for.
Cinigene’s success is the only thing preventing Biocon from being vertically
integrated. To tackle that, they could take expertise from senior staff of other
companies on how they have gone about establishing their ground in clinical
trials. The new recruits need to be introduced to clinical trials and animal testing
techniques(if they have the tools for that) as part of their training. This could help
benefit the whole team as they would discuss amongst themselves ,since the
trials being something they haven’t ventured into & the subject is new to them. So
their open culture isn’t completely fading away.
Moreover, in the process of converting from a subsidiary stuck in its shell to a
leader in clinical trials, it can invent/ develop technologies that can make Biocon
a sustainable company in the market ( by launching their own drug formula). It
can merge with big companies and entrepreneurs to work towards a common
goal(more chance for learning). It can also set up factories across India and not
just in Karnataka. It can carry out different marketing activities to improve its
brand name and value.(sponsoring any event in a biotechnological institutes or
any bio-based event in the country ,hiring graduates in campus selections etc.)
With time and experience in the area of clinical trials, they would be able to take
on any major client.
And once the market knows Biocon is vertically integrated, this would
automatically attract more clients even those overseas and it then has a shot of
competing with big pharma giants like GSK
With this they can shoot up from low-medium segment to a high value segment.
It does pertain certain risks but at the same time to keep up with the global world,
it’s demands and trends, one needs to take such risks to expand further.
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Supporting Material - APPLE INC.-
Apple was the first company to reach a trillion-dollar evaluation, showcasing its
dominance in the electronics industry. Apple is also one of the most significant
vertical integration examples. Apple not only sells computers, iPhones and iPads,
but it also designs the software that powers these products.
The company manufactures its custom A-series chips for its iPhones and iPads. It
also manufactures its custom touch ID fingerprint sensor. Apple opened up a
laboratory in Taiwan for developing LCD and OLED screen technologies in 2015. It
also paid $18.2 million for a 70,000-square-foot manufacturing facility in North
San Jose in 2015. These investments allow Apple to move along the supply chain
in a backward integration, giving it flexibility and freedom in its manufacturing
capabilities.
The company has also integrated forward as much as backward. The Apple retail
model, one where the company's products are almost exclusively sold at
company-owned locations, excluding Best Buy and other carefully selected
retailers, allows the business to control its distribution and sale to the end
consumer.
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Supply Chain Planning at Apple Inc
Supply Chain Map of Apple Inc
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Apple’s sales revenue has annually increased through the years and the cost of
manufacturing has been reduced since the company itself manufactures its own
raw materials instead of a third party supplier providing them to the company. it
produces everything in China because of the low manufacturing cost and labour
cost.
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From the above graph it is clear that since the release of the iPhone, Apple’s sales
revenue has skyrocketed. The whole process of production of the iPhones, right
from the manufacturing of raw materials to the assembling of parts to the
distribution of the iPhones to the consumers, has been done by the company.
Through this methodology, Apple has successfully vertically integrated itself.
Another byproduct of vertical integration is customer satisfaction and increased
brand value.
Biocon can use a similar strategy to expand their growth in the pharmaceutical
industry as mentioned in the solution given above.
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Factors to consider:
1) Outsourcing choice:
Increasingly the country of choice for outsourcing of pharmaceutical products,
whether finished or intermediate, is India. Clinical trials services, in particular,
were emerging as prime targets for outsourcing to India. Clinical trials
represented the most expensive part of the drug development chain: nearly 60% of
total development costs, of which nearly 70% went to patient recruitment and
medical personnel. This high growth potential could represent significant
opportunity for Clinigene to reap revenues as a CRO player. The choice for
outsourcing would change in a couple of years to other countries which provide
cheaper labour. Hence the best time to utilize the foreign investment is the
present.
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2) Environmental:
The laws towards the disposal of pharmaceutical waste could become more
stringent in the future which would lead to more problems for disposal such as
increased cost and measure taken for the safe disposal of waste.
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3) Workforce:
The minimum wages in India is cheaper than most countries. This trend could
change in the future. The government could implement laws to increase the
minimum wages of labourers and provide more facilities and benefits to the
workers. Hence the present is the best time to utilize the cheap Indian workforce.
4) Public image and ethical issues:
In the media, Biocon India Group had enjoyed coverage ranging from quiet
approval to fawning praise. Pharma by its inherent nature raises quite a few
moral and ethical questions in its operations. Through careful positioning in the
public eye by targeted image enhancing campaigns, highlighting the Indian-ness
of the company and its focus on sustainable value, and corporate social
responsibility initiatives, Biocon should strength its public perception and hence
provide a cushion in case Clinigene bombed. Biocon should also take care of its
positioning as a drug producer, and not a service provider, through strategic
public marketing. There is a risk of failure or embarrassment if Clinigene were to
collaborate with a Pharma company which uses unethical methods of working.
5) Organizational culture:
Expansion of Clinigene poses questions on whether Biocon’s carefully nurtured
work culture faces any threats. A large influx of new employees and little time to
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inculcate the Biocon culture would lead to the company losing its prided culture
of openness, trust, and collaboration.
6) Financial factor :
A major company like Biocon has to be considerate about where it is putting its
money in. It has to carry out financial analysis to better analyse its risks and
returns.
Putting more money into something that might not yield anything is considered a
waste. But investing can be a boon if it yields a secure future. In this case, a large
amount of money would be required for a rapid growth of Clinigene.
7) Clinigene’s big success :
it could end up dwarfing the rest of the company and sapping the core culture.
The growth could even sidetrack Mazumdar-Shaw and Biocon’s directors into
pursuing a possibly futile dream of creating one of the only fully integrated drug
discovery and development companies in India.
8) Availability of largest pool of patients and large hospitals:
The Indian healthcare sector is expected to reach US$ 280 billion by 2020. Rising
income level, greater health awareness, increased precedence of lifestyle diseases
and improved access to insurance would be the key contributors to growth. The
sector is expected to generate 40 million jobs in India by 2030.
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9) Presence of diverse ethnic pool-
India has more than two thousand ethnic groups, and every major religion is
represented, as are four major families of languages (Indo-European, Dravidian,
Austroasiatic and Sino-Tibetan languages). This enables diverse sample for
clinical trials
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10) Presence of diverse types of climatic conditions -
For example, during summers, temperature may reach up to 500C in some parts of
Rajasthan and western Gujarat, while at the same time the temperature may be
just around 200C in Jammu and Kashmir. Thus allowing stability studies to be
performed with ease in one destination.
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Path 2: The concentration approach -
➔ A concentrated growth strategy involves focusing on increasing market
share in existing markets. This strategy is also sometimes called a
concentration or market dominance strategy. In a stable environment
where demand is growing, concentrated growth is a low risk strategy.
Concentration may involve increasing the rate of use of a product by
current customers; attracting competitor's customers; and/or attracting
nonusers/ new customers.
According to EXHIBIT 3, we can see that Clinigene is leading in the department of
lab services and it is in the top six in the BE/BA studies department. The high
value segments like data management and phase three type trials are dominated
more or less by the foreign markets. So it is safe to assume that they will be the
leaders in this game for a long time to come. Knowing this, it is worth it to really
spend ‘x’ units of capital , labour, time and venture into a segment that Biocon
itself is new to?
This could be one way of seeing the situation. We know Syngene as a subsidiary
is doing exceptional in its field of serving international clients via a R/D
approach. But Clinigene being it’s other subsidiary isn’t serving its intended
function. We may think its a con but at the same time its leading in it’s prevailing
studies & lab services.
So we could very well say that there is nothing wrong for Clinigene to continue
doing what it is and do less value work for companies. It still earns this way and
exponentially contributes to the revenue margins of Biocon.
They can continue to hire young talents , take them under their wing and nurture
them so they grow into the Biocon family. They can be educated with new
advents in the company and can be exposed to the Biocon culture and practices.
In the coming years, they can develop expertise in low-medium segments of the
value chain (BE/BA testing, animal testing, legal expertise in approval and
launch) by taking on as many projects as possible without compromising on
quality.
As it’s continuing to do so , it can follow the highly acclaimed “earn as you learn”
mantra. When there comes a time when Clinigene takes its own time to create a
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breakthrough in it’s studies , it can be ready for more high value work from the
long term client organization who trust Biocon to do their work.
Due to this approach a lot of capital investments that may or may not result in
fruit can be avoided in the first place(low risk) . And due to this approach, the
company’s long yearned for core competencies and values can survive , providing
the company with a sense of satisfaction.
But at the same time, the global pharmaceutical market is rapidly expanding and
growing and the opportunity for Biocon to expand further decreases. The market
can be exploited via Clinigene and this is their chance. So that is the con here.
In addition to this, while still being a small scale subsidiary, they can still plan for
the future by creating a plan of action on how to expand and preparing all the
necessary documentation required to carry it out. Also with continuous work they
can even lead the low-medium segment and show that they are ready for the next
challenges.
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Supporting material - Starbucks -
Starbucks has relied heavily on concentration strategies to become dominant
player in the coffeehouse sector.
The benefits of the strategy is to build a strong reputation within a market and
generate loyalty among the customers. But it has disadvantages because of the
nature of shift of the demand of customers due to innovations in technology. This
may led to the product becoming obsolete, and also a sudden economic turndown
could lead to its failure.
Four concentration strategy options:
Products
Current New
Customers
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As observed from the above statistics, Starbucks spends a large amount of their
capital on the raw materials and finished goods. This implies that there is not
much innovation occurring in the supply chain, that is, there is no backward
integration with the suppliers, instead the innovation happens with the final
products. This shows that their main focus is on the distribution of the finished
products which is their concentration strategy.
The same products are being sold under the same brand name in various stores.
These stores stick to a template design which is followed by Starbucks all around
the world. This indicates the risk factor in this company is low to none. Hence
there is no fear of losing revenue and the growth is consistent since the demand
is ubiquitous.
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Starbucks is a low risk company. It is a mature company which pays dividends to
its shareholders and it is a slow growing company looking for long term goals and
profits rather than quick and short term gains. Over the years Starbucks has
grown a lot in terms of market capitalization and this growth can be attributed to
the concentration strategy of growth. At the time of its i nitial public offering (IPO)
on the stock market in June 1992, Starbucks had 140 outlets, with a revenue of
US$73.5 million, up from US$1.3 million in 1987. The company's market value was
US$271 million by this time. The 12% portion of the company that was sold raised
around US$25 million for the company, which facilitated a doubling of the
number of stores over the next two years. By September 1992, Starbucks' share
price had risen by 70% to over 100 times the e arnings per share of the previous
year
In July 2013, over 10% of in-store purchases were made on customer's mobile
devices using the S tarbucks app.
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Factors to consider:
1) Outsourcing choice:
Increasingly the country of choice for outsourcing of pharmaceutical products,
whether finished or intermediate, is India. Clinical trials services, in particular,
were emerging as prime targets for outsourcing to India. Clinical trials
represented the most expensive part of the drug development chain: nearly 60% of
total development costs, of which nearly 70% went to patient recruitment and
medical personnel. This high growth potential could represent significant
opportunity for Clinigene to reap revenues as a CRO player. The choice for
outsourcing would change in a couple of years to other countries which provide
cheaper labour. Hence the best time to utilize the foreign investment is the
present. If Biocon were to take low risks and not push Clinigene to get all the
business it could, they might end up missing up on a big opportunity to utilize the
outsourcing being done by big pharmaceutical companies.
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2) Environmental:
The laws towards the disposal of pharmaceutical waste could become more
stringent in the future which would lead to more problems such as increased cost
and measure taken for the safe disposal of waste. Hence delaying the progress of
Clinigene could lead to increased costs and lesser profits.
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3) Workforce:
The minimum wages in India is cheaper than most countries. This trend could
change in the future. The government could implement laws to increase the
minimum wages of labourers and provide more facilities and benefits to the
workers. Hence the cost of hiring labourers would increase in the future.
4) Public image and ethical issues:
In the media, Biocon India Group had enjoyed coverage ranging from quiet
approval to fawning praise. Pharma by its inherent nature raises quite a few
moral and ethical questions in its operations. Through careful positioning in the
public eye by targeted image enhancing campaigns, highlighting the Indian-ness
of the company and its focus on sustainable value, and corporate social
responsibility initiatives, Biocon should strength its public perception and hence
provide a cushion in case Clinigene bombed. If Clinigene only took business for
services that were relatively safe, the image of the company would be at safe
hands too.
5) Organizational culture:
Expansion of Clinigene poses questions on whether Biocon’s carefully nurtured
work culture faces any threats. A large influx of new employees and little time to
inculcate the Biocon culture would lead to the company losing its prided culture
of openness, trust, and collaboration. Hence Clinigene could first s tart with
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recruitment of people who fit in the work culture, with a goal of 2 years to allow
the new recruits to acclimatize. This provides enough time for the employees to
inculcate Biocon’s work culture.
6) Financial factor :
A major company like Biocon has to be considerate about where it is putting its
money in. It has to carry out financial analysis to better analyse its risks and
returns.
Putting more money into a venture that might not yield desirable profits is
considered a waste. But investing can be a boon if it yields a secure future. In this
case, since it is a low risk strategy, the money involved in the initial growth of
Clinigene is minimal.
7) Expertise divergence to Clinigene :
If the expansion is done at a steady pace, the other operations of Biocon would not
be overshadowed by Clinigene. Instead of the diverging the focus of Biocon’s
directors and experts into Clinigene, a small team of executives should be
assigned exclusively to Clinigene. Clinigene would continue working for safe
businesses in the low-medium segments of the value chain, that is, Phase I and
Phase II, while an expansion plan is drafted and required manpower and projects
were scouted. Within 2 years, Clinigene operations would be sustainable enough
and organically growing to run on their own without significant attention of the
senior executives being diverted from other major operations.
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8) Availability of largest pool of patients and large hospitals-
The Indian healthcare sector is expected to reach US$ 280 billion by 2020. Rising
income level, greater health awareness, increased precedence of lifestyle diseases
and improved access to insurance would be the key contributors to growth. The
sector is expected to generate 40 million jobs in India by 2030.
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9) Presence of diverse ethnic pool-
India has more than two thousand ethnic groups, and every major religion is
represented, as are four major families of languages (Indo-European, Dravidian,
Austroasiatic and Sino-Tibetan languages). This enables diverse sample for
clinical trials.
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10) Presence of diverse types of climatic conditions-
For example, during summers, temperature may reach up to 500C in some parts of
Rajasthan and western Gujarat, while at the same time the temperature may be
just around 200C in Jammu and Kashmir. Thus allowing stability studies to be
performed with ease in one destination.
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Path 3: The Diversification approach -
➔ Diversification is a corporate strategy to enter into a new market or
industry in which the business doesn't currently operate, while also
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creating a new product for that new market. Apart from this they can also
gain huge chunks of revenues adding to their growth.
Over the years we have seen many companies who have taken this approach and
turned themselves into global leaders.
To name a few there is ITC which transitioned from manufacturing & selling
tobacco to selling confectionaires and notebooks & stationery etc.
There is G
SK itself, a pharma giant ,which apart from manufacturing drugs have
diversified into consumer goods like Horlicks, ENO, Iodex etc.
We also have IKEA w hich follows a different diversifying approach. IKEA
identifies itself with a mission to provide well-designed products at a lower price
than anyone else can offer. And now it’s selling televisions. Is this the typical
adjacencies thinking? “Hey, if our customers are buying furniture, they might also
be in the market for TVs. Why not capture that business while they’re already in
our stores?” Well, no, I KEA does not see itself as entering the TV market at all.
Instead, the company aims to solve a furniture challenge that many of its
customers complain about: how to fit the TV—and all the components, gadgets,
and tangles of wires that come with it—more seamlessly into the living room. So
IKEA has integrated the television into a furniture solution. IKEA is not trying to
enter a new business (retailing electronics); rather, it’s enhancing the value
proposition of its current business (functional home furnishings).
Biocon can also be expected to diversify into nearby biological and chemical
sectors of manufacturing since they possess the technical know hows.They can
produce anything that is related to modifying their plant processes,parameters,
equipments into a combination that produces another product or gives the initial
molecule for those products.
With this said , they can diversify into nutritional products for different age
groups in the society.
They can indulge into making protein powders for the youth or milk powder for
newly born babies. They could also make energy drinks for the sports industry.
They could diversify into making pesticides and fertilizers to help the farming
sector of the country. Insect control sprays could be used in household as well.
They could move into the beauty products industry providing high values
cosmetics and low valued products like face creams, sanitizers, face washes,
soaps and even detergents.
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Supporting Material- ITC LTD -
ITC was established by UK-based tobacco major BAT( British American Tobacco).
It initially set up the Peninsular Tobacco Company (Peninsular), a cigarette
manufacturing, tobacco procurement and processing unit. In 1910, it set up a
full-fledged sales organization named the Imperial Tobacco Company of India
Limited (Imperial). To cope with increasing demand, BAT set up another cigarette
manufacturing unit (in Bangalore) in 1912.
ITC has been constantly making efforts to de-emphasize its tobacco business. Its
corporate strategy aimed at creating multiple avenues of growth based on its core
competencies. In line with this strategy, ITC's diverse strengths were being
leveraged across three product groups - Lifestyle Retailing, Greeting Cards & Gifts
and Branded Packaged Foods. The company aimed at generating 40 percent of its
total revenues from such diversified businesses. To achieve this, it planned to
invest around Rs. 26 billion to Rs. 28 billion in various ventures by 2006. Analysts
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felt that ITC's diversification, especially into areas such as branded garments,
aimed at improving its brand image, which, in turn, may help it grow its core
business.
According to a report in 2010, though cigarettes continue to contribute more than
70% of total net revenues, the operating profit earned from this business has
sequentially dropped from 83% of the total profit in the quarter ended June 2010 to
77.5% in the September quarter this fiscal. The cigarette business contributed 62%
of revenues and 88% of the operating profits.
In the latest September quarter( 2009) , the y-on-y growth in net sales stood at
16.3% with all the businesses giving a handsome growth while the net profit grew
by 23.5%. Logging a growth of 22%, the non-cigarette FMCG business has been the
fastest growing business revenue-wise. This was closely followed by the
agri-business that grew by 21.5%.
Comparison of earnings across segments showed that paper & packaging
business had achieved the highest growth of 32% followed by the hotel business
which had been dented due to recessionary pressures, is now on its path of steady
recovery. The only loss-making business in ITC’s portfolio continues to be the
non-cigarette FMCG business. It includes packaged foods, garments, stationary
products and personal care products.
The earnings still remain negative because of the high costs involved in the
business development, brand building and gestation costs of other packaged
foods and personal care products. However, the good news for investors is that
this fast-growing segment has been steadily reporting declining losses quarter
after quarter.
Though ITC continues to invest and grow in its traditional business of cigarettes,
it is well-equipped to beat the intense competition in the non-cigarette consumer
and agri space due to its large distribution network and the vast experience in
handling cigarette brands. Investors shall continue to benefit as the company’s
strategy of de-risking its portfolio is executed successfully.
According to a report in 2016, the growth pattern is shown as below-
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Also ITC monitors its risk vs returns as in diversification there are a lot of risks
involved upto and they should make sure they don’t run into losses.
Diversifying is very ticky. But ITC proved to be a strong company taking
leadership by investing in the required resources. Diversifying isn’t a short term
process. It is in fact time consuming and your new products might not succeed
immediately. Over time as they are recognized by more and more people, they will
be remembered as a brand that is there in many sectors compelling people to
think it is a successful brand.
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Biocon can follow close patterns followed by ITC in becoming who they are today
but it is a time consuming process of patience and slow growth. In a few years ,
Biocon may pick up the brand value
But for that it has to direct a lot of resources into diversification and its expansion
in that direction.
Factors to consider:
1) Financial factor:
A major company like Biocon has to be considerate about where it is putting its
money in. It has to carry out financial analysis to better analyse its risks and
returns.
Putting more money into a venture that might not yield desirable profits is
considered a waste. But investing can be a boon if it yields a secure future. In this
case, manufacturing and distribution of chosen product/service should be
financially viable for Biocon.
2) Product Identification:
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When choosing a product to diversify into, which products yields the most
revenue for Biocon should be considered.
3) Location factor:
There should be a demand for the product in India.
4) Technical Feasibility:
The product must be technology feasible by Biocon.
5) Profitability:
How well is the product going to do in the market and if the product is able to
make a substantial profit for Biocon
6) Raw materials:
Are the required raw materials available at an economic price to Biocon?
7) Availability of Experts:
Personnel who have prior experience on working with the product should be
available. These experts should be hired and should help develop the product.
Final Conclusion
Now that we have seen the three solutions to our case study problem, we’re at a
stage where we have to go with one of the solutions as its growth strategy. The
company obviously cannot expand via all the 3 strategies given above. It has to
pick the right one considering all the factors mentioned above.
We have gone through each of them and decided that Biocon India Group should
take the Path 1 mentioned. It is the best way for them to expand given the
advantages and disadvantages :
➔ The Vertical Integration approach does have risks associated with it, but
given the current market situation where pharma industries are growing at
a rapid pace, it seems like the most viable option. The Concentration
method leaves them behind in this race and the company’s future would be
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affected as clients or media might target & question their innovative
abilities and their their boldness to take on challenges. Losing their so
called ‘’cultural values’’ is in no way comparable to the leap they would take
in the market being vertically integrated. So it is logical for them to lose
their ‘culture’ to secure good future prospects. But the risks are high. It is
advisable for Biocon to visit a consultant and plan the steps needed to
move forward in this direction.
➔ The third path which is diversification can also be used but in the case of
Biocon it is not advisable. Biocon is pharmaceutical company which deals
primarily in generic drugs. They have the knowledge of the biological or
biochemical processes happening in their sector. Expanding into new
territories and products in which they have little knowledge about seems
pointless. It is highly time consuming and they still have a long ladder to
climb if their products are not in niche markets. They have to invent new
techniques , learn new techniques and spend money on all of this.They
would have to spend a lot on external agents to help with the market
survey, to know the competitors etc.
➔ There is also no guarantee that once Biocon launches its new products ,
they will succeed. They could very well lead to losses. To be on the safe
side, the vertical integration approach implements what they are
knowledgeable about making it easier for them to tackle problems here.
➔ To gain more insight we will take a look at the following models of
Pharmaceutical industries which can be used or applied to Biocon India
Group for its products or for picking a suitable growth strategy for
long/short term (based on the market conditions) -
1) SWOT Analysis model :
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2) PESTLE Analysis model :
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3) BCG MATRIX model for various products :
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4) Porter’s five forces model :
5) Igor Ansoff growth matrix model :
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