Beruflich Dokumente
Kultur Dokumente
A) Match the provided generic names with the penicillins shown below in the
provided space
Benzyl penicillin Ampicillin Amoxicillin Methicillin Naficillin Cloxacillin
Oxacillin Piperacillin Carbenicillin Sultamicillin Sulbactam Bacampicillin
OEt O CH3 H
H2N H
H N H N
N N S
S S CH3
CH3 CH3
O CH3 O N CH3
O N CH3 N O
O O HO
COOH COOH COOH
Due to…………………………………………………………………………………………………………
Due to ……………………………………………………………………………………………………….
Due to
………………………………………………………………………………………………………………………………………
How would the duration of action of the penicillin (f) could be prolonged
Mention the generic name of the modified analogue and draw its chemical structure
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B) Complete the missed portions of the chemical structures in each of the following
cephalosporins
(5.5
Marks)
H3C HN
H
O H H S
S HN S
HN
N O N
O O NH2 O
S O O NH2 O O O
O O C CH3 O OH
O O O
O H2C COOH
O
b) Cefuroxime axetil
a) Cefoxitin c) Ceftazidime
S H3C
H2N H H H
N S HO
N H 4
N S
N O O 7
N 3
OCH3 O 2
COOH COOH
d) Cefepime e) Imipenem
Cephalosporoic acid
H+, - H2O