Certain infectious and parasitic diseases

Drug Type of ADR Use of Drugs

voriconazole Metabolism/PK antiinfective (fungal)
ribavirin Efficacy antiviral (hepatitis C, viral hemorrhagic fever)
peginterferon alfa-2a Efficacy Hepatitis C and B medication
peginterferon alfa-2b Efficacy Hepatitis C and B medication
abacavir Toxicity/ADR prevent and treat HIV/AIDS
atazanavir Other prevent and treat HIV/AIDS
efavirenz Metabolism/PK prevent and treat HIV/AIDS
nevirapine Other prevent and treat HIV/AIDS

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
(immune-related drugs)
Drug Type of ADR Use of Drugs
tacrolimus Dosage,Metabolism/PK immunosuppressant
azathioprine Dosage,Toxicity/ADR rheumatoid arthritis medication
azathioprine Dosage,Toxicity/ADR rheumatoid arthritis medication
allopurinol Toxicity/ADR gout medication

Diseases of the gastro & urinary track

Drug Type of ADR Use of Drugs
tolterodine Other antimuscarinic
omeprazole Efficacy reflux and stomach acid medication
rabeprazole Efficacy stomach acid medication
lansoprazole Efficacy ulcer medication

General medicine
Drug Type of ADR Use of Drugs
celecoxib Dosage NSAID
flurbiprofen Toxicity/ADR NSAID
codeine Efficacy,Toxicity/ADR pain medication
methadone Dosage pain medication
oxycodone Efficacy,Toxicity/ADR pain medication
tramadol Dosage,Efficacy,Toxicity/ADR pain medication

Diseases of the nervous system

Drug Type of ADR Use of Drugs
phenytoin Toxicity/ADR,Metabolism/PK anti-epileptic, anticonvulsant
bipolar disorder, epilepsy, and trigeminal
carbamazepine Toxicity/ADR
neuralgia medication

Mental and behavioral disorders

Drug Type of ADR Use of drug
atomoxetine Efficacy,Toxicity/ADR ADHD medication
amitriptyline Efficacy,Toxicity/ADR antidepressant
citalopram Metabolism/PK antidepressant
clomipramine Toxicity/ADR antidepressant
doxepin Efficacy antidepressant
duloxetine Toxicity/ADR antidepressant
escitalopram Efficacy,Toxicity/ADR antidepressant
imipramine Other antidepressant
mirtazapine Efficacy,Toxicity/ADR antidepressant
nortriptyline Efficacy,Toxicity/ADR,Metabolism/PK antidepressant
sertraline Metabolism/PK antidepressant
venlafaxine Efficacy,Toxicity/ADR antidepressant
risperidone Other antipsychotic
clobazam Toxicity/ADR anxiolytic and anticonvulsant
fluvoxamine Efficacy,Toxicity/ADR,Metabolism/PK OCD medication
paroxetine Efficacy,Toxicity/ADR,Metabolism/PK OCD medication

Diseases of the heart and circulatory system

Drug Type of ADR Use of drug
flecainide Other antiarrhythmic
propafenone Dosage antiarrhythmic
metoprolol Efficacy,Metabolism/PK beta blocker
norepinephrine Toxicity/ADR blood pressure
rosuvastatin Other cholesterol-lowering medication
simvastatin Toxicity/ADR cholesterol-lowering medication
warfarin Toxicity/ADR prevent blood clots
clopidogrel Efficacy,Toxicity/ADR prevent heart attack/stroke

Neoplasms (cancer)
Drug Type of ADR Use of drug
capecitabine Toxicity/ADR,Metabolism/PK chemotherapy (breast, gastric, colorectal)
tamoxifen Efficacy,Toxicity/ADR chemotherapy (breast)
chemotherapy (colon, esophageal, stomach,
fluorouracil Toxicity/ADR,Metabolism/PK
pancreatic, breast, cervical)
irinotecan Toxicity/ADR chemotherapy (colon, small cell lung)
rasburicase Toxicity/ADR chemotherapy (combined therapy)
tegafur Toxicity/ADR,Metabolism/PK chemotherapy (gastric)
chemotherapy (leukimia), autoimmune
mercaptopurine Dosage,Toxicity/ADR
diseases (Chron's disease, ulcerative colitis)
megestrol Dosage,Toxicity/ADR Cancer, appetite control