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KIDNEY DISEASE
A research paper
BACHELOR IN NURSING
By
Jonah Anzo
April 2015
Kidney failure or renal failure is a complete loss of kidney functioning and is the
destruction of the glomerular that are responsible for the filtration of the fluids in the body. It
is a major health problem that affects most people and it comes in two forms, the acute are
partially reversible whereas chronic is irreversible and leads to progressive renal tissue
destruction and loss of functioning ( Teixeira Lima, Morais, Coelho, Oliveira Neves, Melo,
& Barbosa, 2012). It is also a public health problem (Gerogianni & Babatsikou, 2014) that
tends to take dimensions of epidemic and has serious impact on the quality of life of patients
undergoing haemodialysis, the social spiritual mental and physical life of a person. According
to (Brunner & Suddarth, 1988), renal failure is the result whit it fails to renew the body
metabolic waste or perform their regulatory functions. The substances normally eliminated in
the urine accumulate in the body as a result of impaired renal excretion and leads to a
disruption in endocrine and metabolic functions as well as fluid, electrolyte, and acid base
disturbance (p.1033).
Chronic renal failure exists when the kidney are no longer capable of maintaining an
internal environment that is consistent with life and damage to the kidney irreversible. It is
different from acute renal failure and it is progressive and irreversible damage to the kidney.
This essay will highlight on kidney (Renal) failure specifically the chronic renal failure. It
will cover the pathophysiology, clinical manifestation, and the complications together with
medical, surgical and nursing care given to a patient considering their cultural, ethical, legal
and professional aspect of care given to them. Not only needs that but also considering their
Chronic renal failure is different from acute renal failure and it is advanced and
essentially through four stages, the diminished renal reserve, renal deficiency and renal
failure. The specific pathophysiologic mechanism depends on the causal disease causing the
destruction to the kidney. During chronic renal failure, some of the nephrons including the
glomeruli and tubules are thought to remain intact while others are devastated (p.1665). As
renal function declines, the end products of protein metabolism, which it plays, are role of
excreting it in urine that is accumulated in the blood. When this occurs it imbalances the body
chemistry and chances the systems of the body like cardiovascular, hematologic,
gastrointestinal, neurologic, and skeletal system. In the research of (Brunner & Suddarth,
1988) they said that the patient with chronic renal failure tents to retain salt and water in the
body were it then leads to oedema formation, congestive heart failure, and hypertension
(p.1037)..
Patients with chronic renal failure may develop more of signs and symptoms at time and it
all begins with one or more symptoms like fatigue and lethargy, headache, general weakness,
gestational symptoms, especially anorexia, vomiting, diarrhoea, the bleeding tendencies, and
mental confusion. There is also decreased salivary flow, thirst, a metallic taste in mouth, loss
of smell and taste, and parotitis or stomatitis. Bartuuct (1995), states that if active treatment is
begun early, the symptoms may dissappear. Otherwise, these symptoms become more
marked, and others appear as the metabolic abnormallities of uremia affect virtually every
body system. The chronic renal failure patient will gradually become more and more drowsy,
the respiration becomes Kussmaul in character, and a deep coma develops, often with
else death will follow soon. The other signs and symptoms include, anaemia, hypertension of
160/100, loss of appetite, nausea and often vomiting with no good reason, wasting of muscles
The patient with chronic renal failure may encounter some complications where it varies
during the sessions. They also often develop infections and bacteraemia due to various
admissions occur due to vascular access dysfunction.1 Patients on peritoneal dialysis often
experience episodes of peritonitis that may lead to dysfunction of the peritoneal membrane
and eventually transfer of the patient to haemodialysis.8-12 On the other hand, transplanted
patients may face rejection episodes and increased rate of infections and cancers ( Tzanakaki
According to (LeMore & Burke, 2008) they said that the aim of management is to help the
diseased kidney to maintain homeostasis for as long as possible. All factors that are
contributing to this problem should be identified and treated, especially the irreversible ones
(p.887). In medical care according to (Bartuuct, 1995), drugs are given to firstly to reduce
and keep the blood pressure down to at least 140/90. Diuretic drugs like frusemide are given
to reduce extra cellular and oedema. Some of the important drugs are given to control the
concentration of sodium and potassium in serum and urine. Aluminium hydroxide antacids
necessary, since, since a protein-restricted diet does not give the necessary complement of
from taking protein diets because unlike carbohydrate and fats, which body can store, excess
protein are then excreted by the kidney through metabolism and becomes nitrogenous waste
in the kidney.
In surgical care of the Chronic renal failure patient, because the kidney is totally destroyed
and cannot function any more, most of the patient are undergone the process of
haemodialysis or peritoneal dialysis and mostly are kidney transplant were it involves
transplanting a kidney from a donor or human cadaver to a recipient who has end-stage renal
disease. Most patients are on dialysis for months and years prior to transplant. Bartuuct
(1995), transplantation provides the patient with more normal life styleand is less expencive
than dialysis (p.1038). The pateint with kidney malfunctioning may or may not be removed,
and dialysis is instituded untill a kidney from a suitable donor is obtained. The available
treatments for CRF are continuous outpatient peritoneal dialysis, automated peritoneal
technological and therapeutic advances in dialysis are contributing to a greater survival rate
of patients with chronic renal diseases, since these treatments alleviate symptoms of disease,
preserve life and partially replace the renal function, however they do not promote disease
healing. Despite the great scientific advances before the dialysis therapies, the patients with
chronic renal failure have limitations in their daily lives, since they experience multiple
losses, which generates conflicts, feelings of guilt, frustrations and depression, both in the
Bezerra, Onofre, Araujo, & Silva, 2014). Hemodialysis cleans and filters your blood using a
machine to temporarily rid your body of harmful wastes, extra salt, and extra water
Hemodialysis helps control blood pressure and helps your body keep the proper balance of
Dialysis can replace part of the function of your kidneys. Diet, medications, and fluid
limits are often needed as well. Your diet, fluids, and the number of medications you need
will depend on which treatment you choose (National Institute Of Health [NIOH] , 2007).
The patient with chronic renal failure requires astute nursing care to avoid the
complications of reduced renal function and the stresses and anxieties of dealing with a life
threatening ilness. According to (LeMore & Burke, 2008), potential nursing diagnosis for this
patient include alterations in fluid and electrolyte balance related to decreased urine output
and dietary and fluid restriction, alteration in nutrition, lessn then body reqiurements, related
fatigue and altered self-care related to dependency and role changes. Nursing care is directed
at assessing fluid and elctrolyte status and identifying potencial sources of fluid imbalance,
implementing a dietary programe to ensure proper nutritional intake within the limits of the
treatment regimen, providing explaination and informations to the patient family concerning
the renal failure. In the first state of examination, the nursing care is mostly to assess fluid
and elctrolye status on serum electtrolyte, daily weight changes, intake and output balance,
skin tugor and presence of edema, distention of neck veins, bllod pressure and puls rhythm,
haemodialysis, it may affects their quiality of life, especially their spiritual, emotional and
social life. According to (Bartuuct, 1995) “the provision of social support to patients with
chronic renal failure is associated with reduction in depressive symptoms, positive perception
of their illness and their general satisfaction with life”. For patients with chronic diseases,
daily activities and social support are of great importance for maintaining a satisfactory
quality of life. Social support and integration in the community are important factors, which
help patients to be adjusted to a chronic illness. should be noted that support by the family,
friends and caregivers to patients with renal disease plays a very important role, since it helps
patients to have an increased compliance to the treatment regimen. They can not even involve
them selves in any social activivties when they undergone haemodialysis. Most of the patient
with chronic renal failure may not enjoys rest of their life with social eactivities.
In the spiritual need of the patient with chronic renal failure, they really need spiritual
need to enhance them and give the hope to complete their treatment. According to (Ferrer, et
al., 2012), Spiritual well-being was significantly associated with various quality of life
variables, health status, personal happiness, or religiosity in patients on dialysis. There was
or age. Spiritual well-being is relatively low in dialysis patients. Spirituality may play an
important role on psychological well-being, quality of life, and selfrated health for patients on
need in these patients. Spirituality provides the means through which patients can question
the meaning, significance, purpose, and direction of his/her life, disease, or suffering. In some
cases, spirituality becomes one of the primary resources available to the patient for dealing
believe that, in any case, evaluating and prioritising spirituality are essential components of
integrated, holistic therapy for patients with severe health problems or end of life situations.
In many cases, patients on haemodialysis and their families turn to spirituality or religion as a
context, it has been shown that spiritual well-being is related in a systematic and significant
manner with quality of life, social support, level of satisfaction, decreased symptoms of
depression, improved satisfaction with nephrological treatment, and higher survival rates.
These patients enjoy spiritual well-being when they have a sense of purpose, coherence, and
personal fulfilment in life, and when they retain the belief that life has value. In this sense,
health professionals must recognise the existence of spiritual needs in their patients when
applying high-quality, integrated health care, and should evaluate patient spiritual well-being
In chronic renal failure patient, they also are in great emotion about their own life and
what they gone achieve in life. All of their emotions are in that state of haemodialysis and
they may expect more of emotional support from their guardian and the family members. A
research study of (Gerogianni & Babatsikou, 2014) reached to the same conclusion, since
married family life is a major contributor of wellness, self-esteem and self-confidence for
patients with chronic renal failure. At the same time, data collection of another research study
about patients’ family satisfaction in the context of chronic renal disease and their spouses
showed that patients were consistently more satisfied with their marriages than their
husbands. Consequently, marital life is very important for patients who are forced to abstain
Chronic renal failure is the progressive and irreversible loss of the kidney functions that
can start with an acute clinical picture, in a slow and gradual manner. This consists of the
final stage of evolution of many kidney diseases and, in some cases, it is identified. Most of
these case are irreversible and it is life threatening. This particular disease mostly affects the
nephrons and glomerulus of the kidney; for that’s where most of the filtration is done, and
when they are destroyed, kidney can no longer function well to filter out the waste from the
body. Chronic renal failure is mainly caused by some of these factors like diabetic
There are few of the signs and symptoms of chronic renal failure can be detected earlier
such as severe anaemia, hypertension of 160/100, nausea and vomiting, loss of appetite,
wasting for no reason, urine like breath smell and bleeding in the skin. Patient with renal
failure are may go through some complication as they are on haemodialysis, often experience
during the sessions. They also often develop infections and bacteraemia due to various
managed through investigation by performing urinalysis, urine culture, blood urine nitrogen,
creatinine, complete blood count, renal ultrasonography, and kidney biopsy were it is done to
identify underlying disease. There are some medications given to chronic renal failure firstly
to reduce the blood pressure to at least 140/90, diuretics like frusemide are given to reduce
extracellular fluids and oedema with good diet control of carbohydrate and fats and enough
Most of the patients are gone through kidney transplant were they replace their kidney
with the kidney form healthy human being, and most of the patient are successfully treated
dialysis. In this case nursing care is highly appreciated to avoid further complications, and
nursing care is to monitor the patient condition and diagnosing them and providing
When the chronic renal failure is undergoing haemodialysis or peritoneal dialysis they
may not enjoy some aspects of life, there spiritual aspects of life may be in greater need and
they need spiritual care to have hope in them self, their guardian and the health workers. They
also need social support from the family members and friends to ensure they are in this
quality of life and may enjoy his or her life. Social need of the patient undergoing
haemodialysis may be affected. However, their emotional need is really important and they
may emotionally affect and may lead to further complication. Therefore, all patients who are
having chronic renal failure must have met all the quality aspects of life.
Brunner, L. S., & Suddarth, D. S. (1988). Renal & Urinary Problem. In L. S. Brunner, & D.
S. Suddarth, Text book of Medical -Surgial Nursing (6th ed., pp. 1033-1044). U.S.A:
J.B. Lippincott Company Ltd.
Ferrer, A. R., Arenas, D., Cascales, R. F., Pascual, F. F., Blazquez, N. A., Gil, T., et al. (2012,
April). Evaluation of spiritual well-being in haemodialysis patients. 32(6), 731-742.
(2008). Nursing care of Client with Kidney dissorder. In P. LeMore, & K. Burke, Medical
Surgical Nursing (4th ed., pp. 882-915). New Jersey, Upper Saddle River: Pearson
Education Inc.
Souza Araujo, R. C., Silva, R. R., Bezerra, M. X., Onofre, M. S., Araujo, A. V., & Silva, K.
P. (2014, June). Therapeutic itinerary of patients with chronic renal failure under
dialytic treatment. Journal of Research Fundermental Care online, 6(2).
Teixeira Lima, F. E., Morais, V. S., Coelho, E. L., Oliveira Neves, F. M., Melo, E. M., &
Barbosa, I. V. (2012, September). IMPLEMENTATION OF NURSING PROCESS
TO PATIENTS WITH CHRONIC RENAL. Journal of Nursing, 9(6), 2167-76.
Tzanakaki , E., Boudouri, V., Stavropoulou, A., Stylianou, K., Rovithis, M., & Zidianakis, Z.
(2014). Causes and complications ofchronic kidney disease inpatients on dialysis.
HEALTH SCIENCE JOURNAL, 8(3).