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Creamino -

The source of
creatine for
animal nutrition
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AlzChem is an INTERNATIONAL CHEMICAL COMPANY. Innovative, competent and reliable, AlzChem
successfully positions itself with proven and new products in known and future markets in the world of
specialty chemicals.

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ALZCHEM MARKETS

AGRICULTURE NUTRITION FINE CHEMISTRY RENEWABLE METALLURGY


ENERGY
With our specialty The Nutrition segment Based on coal, lime Today's hope carrier in AlzChem offers
products, we comprises of the and air, we build a renewable energies - reliability, quality,
contribute to efficient manufacture and widely branched wind energy and flexibility and
and sustainable marketing of high-quality product family tree photovoltaics - are innovation in key areas
agricultural production products in the field of using calcium carbide important markets for of the steel industry.
worldwide. food supplements, and calcium our products.
pharmaceutical cyanamide.
applications and the
manufacture of
cosmetics.

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ALZCHEM‘S NUTRITION BRANDS

SPECIAL SOLUTIONS FOR NUTRITION

Creapure® Alipure® Crenipure® Livadur®

For fitness, Antioxidans, Additive for Creatine


medical and source for cosmetics formulation for
dietary enzymes in the best agers
supplement body

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CREATINE

• is an essential biomolecule in the organism of vertebrates

• is endogenously produced from amino acids (Gly, Arg, Met)

• stored where energy is needed (muscle, heart, sperm, macrophages)

• protects and stabilizes cells

• associated with meat and meat quality (kreas = meat)

• DIRECT source of energy in the body (via PCr)

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APPROVED HEALTH CLAIMS IN HUMAN NUTRITION

CREATINE CREATINE
HEALTH CLAIMS SUPPLEMENTATION

Average adult Only ~50% of the 3 g of Creapure per


has around 80 - daily creatine day help to increase
130 g of creatine requirement is met body strength &
in the body. through food intake. muscle recovery

• Creatine increases physical Recognized in sports nutrition and beyond


performance with a daily intake of 3g of
creatine (Regulation (EU) No 432/2012) • increase physical performance

• Creatine enhances resistance in • Increase muscle strength


muscle training in adults over the age • Increase lean body mass
of 55 (Regulation (EU) No 672/2017)

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CREAMINO - COMPETENCE

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CREAMINO - THE DIRECT WAY TO CREATINE

• is granulated guanidinoacetic acid (GAA)

• is fuel for the body‘s own energy reserves

• is the natural precursor of creatine with

FULL CREATINE EFFICIENCY

• is stable throughout the feed manufacturing process

• is the only authorized creatine source for animals (as nutritional additive)

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ENDOGENOUS CREATINE SYNTHESIS

• The endogenous synthesis of guanidinoacetic acid requires


amino acids and an enzymatic multi-step synthesis.
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CREATINE IS DIRECT ENERGY

Phospho
ATP
creatine

Creatine
kinase
Creatine ADP + H+

• Creatine as ‚battery pack‘ supplies, recycles and buffers


energy and makes it readily available whenever needed.
https://www.wasistwas.de/details-wissenschaft/was-ist-ein-solarauto.html 10
Creatine recovery after extrusion at 130°C is 85%
Van der Poel et al., JAPAN, accepted

Creatine recovery after extrusion in a basal dog


food diet (dry) supplemented with CMH
2900 2850
2800
2700
2600
2500
2410
2400
2300
2200
2100
Creatine (mg/kg)

Basal dry dog food including supplemented CMH


Basal dry dog food including CMH after extrusion

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GAA recovery after extrusion at 130°C is 99%
Van der Poel et al., JAPAN, accepted

GAA recovery after extrusion in a basal dog food


diet (dry) supplemented with Creamino
2600
2550
2500
2450
2400
2350
2350 2310
2300
2250
2200
2150
2100
GAA (mg/kg)
Basal dry dog food including supplemented Creamino
Basal dry dog food including Creamino after extrusion

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CREATINE IS SCARCE

Feed ingredient Creatine content (mg/kg) Samples (n)


Mean CV Range
Grain n.d. n.a. n.a. 39
Blood meal 67 87 9-152 8
Fish meal 1146 19 776 - 1410 7
Meat meal 885 160 103 - 4376 20
Meat & bone meal 199 43 106 - 342 6
Whey powder 848 32 0 - 1100 7
Milk powder 1206 59 731 - 2030 3

• Creatine is nearly absent in animal feed


• Animals have to produce all their creatine endogenously

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CREAMINO - APPROVED AS A SOURCE OF CREATINE

• EU: First authorized in 2009 for broilers - and recently extended for pigs

• US: Approved in 2016 for broilers and turkeys (21 CFR § 573.496)

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