PREPARATION 19: ELIXIR

ELIXIR

 A clear, sweetened hydro alcoholic liquid 0.15mL

intended for oral use containing flavoring 1.5mL
substance or active medicinal agent. 3mL
 Their primary solvents are alcohol and 4.8mL
water
 Glycerin, sorbitol and syrup are additional
0.06mL
solvent and/or sweetening agents 0.05mL
 Alcohol solvent 3mL
 10-12% self-preserving
 5-40% (limit)
 used as vehicle or for their therapeutic Procedure: LOW ALCOHOLIC
effect 1. Mix alcohol, glycerin and 7.5 mL of purified
2 GROUPS water thoroughly
2. Add compound orange spirit and agitate.
 flavored 3. Cover and let it stand for 24 hours
 medicated 4. Filter until a clear solution is obtained
5. Dissolve sucrose by agitation in the filtrate
Propylene Glycol- can be used as substitute for 6. Add enough water to complete the volume
glycerin and alcohol
Procedure: HIGH ALCOHOLIC
Alcohol- excellent solvent for drugs but it
accentuate the saline taste of bromides and similar 1. Mix compound orange spirit and saccharin
salts in 7.5 mL alcohol
2. Add glycerin and stir
METHODS OF PREPARATION
3. Add sufficient amount of alcohol to make
 Simple solution with agitation the required volume
 Admixture of 2 or more liquids Procedure: ISO-ALCOHOLIC
PREPARATION 19: ISO ALCOHOLIC ELIXIR
 Mix 15 mL of Low Alcoholic Elixir and 15 mL
Category: Non medicated elixir of High Alcoholic Elixir

Synonym: Iso-Elixir High to Low - manner of addition

Description of Final Product: A clear, colorless, Label: White Label

hydro alcoholic solution
Use/s: Intended as general vehicle for various
preparation that requires solvent of different
alcoholic strength
Container: 30mL amber bottle
Remarks
 When Iso-alcoholic elixir is specified in a
prescription, the proportion of its 2
ingredients to be used is that which
produce a solution of the required alcohol
strength.
 The method – admixture of two or more
liquid ingredients

Compute for the alcoholic strength (%v/v) of the

prepared alcoholic elixir.

Reviewer prepared by the cute auditor of 1EPH: Ulangco, Milani Joy R.

HIGH ALCOHOLIC ELIXIR 0.255mL
13.95mL
0.3mL
0.00075mL
6mL
1.5mL

Procedure

1. Triturate terpin hydrate

2. Dissolve terpin hydrate in alcohol
3. Add successively orange peel tincture,
benzaldehyde, glycerin and syrup. Stir
after every addition
4. Add sufficient amount of water
5. If it becomes turbid, filter until clear

Label: White label

Container: 15mL amber bottle

Remarks

Method of preparation- simple solution with

PREPARATION 20: TERPIN HYDRATE ELIXIR agitation
Category: Medicated Elixir Orange peel tincture- flavoring agent
Each 100ml of THE contains nlt 1.53 g and nmt Benzaldehyde- preservatives
1.87 g of TH. The preparation has 1.7 g of TH per
100 mL of elixir. Glycerin & Syrup- thickening agent and
sweetening agent
Synonyms:
Dilution of this elixir with water causes
Elixir Terpin Hydrate precipitation of TH
Terpinol Elixir

Elixir Terpin Hydrate PREPARATION 21: SPIRIT

Terpin Hydrate Oral Solution (former official name
of THE)
Description of Final Product: It is a colorless with
striations and it contains 43% alcohol
Use: Expectorant
SPIRIT
 A clear, saturated, alcoholic (over 60%
alcoholic content) or hydro alcoholic
solution of volatile oil or aromatic
substances
 The active ingredient in spirit like aromatic
water may be solid, liquid or gas
 Used internally for their medicinal value
 Flavoring agent
 Stored in tight light resistant container and
in a cool place, preventing evaporation and
volatilization of either the alcohol or the
active principles


Reviewer prepared by the cute auditor of 1EPH: Ulangco, Milani Joy R.

PREPARATION Synonyms:

 Simple Solution- 65 mL volatile oil/1000 Essence of Peppermint

mL preparation
 Solution with Maceration- macerates Spiritus Menthos Piperitas
leaves in water to extract water soluble Description of Final Product: A clear brilliant, green
components solution with odor and taste of peppermint
 Distillation
Brandy – fermented juice of ripe grapes Use/s:
Whisky – fermented mash of wholly
germinated malted cereal grain  used as carminative
 for nausea and vomiting
PREPARATION 21: COMPOUND ORANGE
SPIRIT

Category: Non-Medicated Spirit

1.5mL
0.15mL
Synonym: Spiritus Auranti Compositus

Description of Final Product: It is alcoholic solution

with the odor of
Procedure
Orange between 65.0% - 70.0% of C2H5OH
1. Macerate peppermint leaves in 20 mL of
Use: Flavoring agent purified water for 1 hour with agitation
2. Strongly express through filter paper to dry
the leaves and add 20 mL of alcohol to
6mL macerate leaves and allow to stand for 2
1.5mL hours with frequent agitation
0.6mL 3. Filter through muslin cloth or filter paper
0.15mL 4. Add peppermint oil to filtrate and complete
to complete the required volume with
alcohol

Label: White Label

Container: 30 mL amber bottle

Procedure
Remarks
1. Measure 21.75 mL alcohol
2. Add orange oil, lemon oil, coriander oil and
anise oil, stirring after each addition until
the oil is mixed or dissolved thoroughly
3. Filter until clear, add sufficient amount of
alcohol to make 30 mL
Label: White Label
 Method of preparation- maceration method
 Macerate the leaves thoroughly with water
to exhaust the leaves of water soluble
extractives.
 Traces of water in the apparatus- make the
solution turbid

Container: 30 mL amber bottle

PREPARATION 23: AROMATIC AMMONIA
Remarks SPIRIT
 Method of preparation- simple solution Category: Spirit
method
 Container- tight and light resistant Synonyms:
 Storage- cold place
Smelling salts

PREPARATION 22: PEPPERMINT SPIRIT Sal volatile

Category: Medicated Spirit Salt of hartshorn

Reviewer prepared by the cute auditor of 1EPH: Ulangco, Milani Joy R.

Description of Final Product: A clear yellow
solution with a strong ammonia odor

Use: used to treat and prevent syncope (fainting)

1.02g
1.08mL
0.3mL
0.03mL
0.03mL
21mL
30mL
Procedure

1. Dissolve Ammonium carbonate in strong

ammonia solution and 6 mL of purified
water (Mixture 1)
2. Stir. Stand for 24 hours
3. In another container, dissolve all the
volatile oils in alcohol (Mixture 2)
4. Slowly add the mixtures (1 & 2)
5. Add enough water to make 30 mL
6. Stand for 24 hours. Agitating occasionally
7. It turbidity occurs, filter it.

Label: Red Label

Container: 30 mL amber bottle

Remarks

 Preserve in tight, light resistant container

at temperature not exceeding 300C
 During inhalation, place a small amount of
the solution between your fingers
approximately 4 inches away from nostrils,
inhale the spirit

Reviewer prepared by the cute auditor of 1EPH: Ulangco, Milani Joy R.