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Clinical science
cover test; in patients with severe MSF with no movement pos- (Figure 5D) and tightened to bring the bellies of SR and LR
sible in any direction, a corneal light reflex estimation technique together by pulling the two ends in opposite direction
measured with prisms placed in front of both eyes was used to (figure 5E). The ends of the silicone band were cut close to the
estimate the deviation. All subjects underwent MRI with axial edge of the sleeve (figure 5F). The sleeve with the bands was
and coronal T2-weighted spin-echo imaging with a slice thick- further secured by placing a suture through them with 5–0 non-
ness of 3 mm. The images were analysed for any abnormality in absorbable green braided polyester suture (Alcon, Texas, USA).
the orbit and shift in muscle position of SR and LR if any and This extra suture placement was done in the earlier cases, but
the findings were documented. The imaging and analysis were later on it was discontinued. The conjunctiva was closed with
performed according to the protocol published by Krzizok and interrupted sutures using an 8–0 non-absorbable monofilament
Schroeder.7 nylon suture (Aurolab, Tamil Nadu, India). An FDT was
repeated to look for the tightness and a medial rectus (MR)
DATA COLLECTION recession was performed if the MR tightness was thought to be
The parameters studied were patient demography, age at onset significant.
of strabismus, duration of strabismus, refraction as spherical
equivalent (SE), AL, preoperative and postoperative limitation MAIN OUTCOME MEASURES
of movements and horizontal and vertical deviation at The main outcome measures were improvement in alignment
2 months, MRI findings, intraoperative and postoperative forced postoperatively, improvement in extra-ocular motility postopera-
duction test (FDT) findings, intraoperative findings of muscle tively and intraoperative and postoperative complications
path, previous strabismus surgery with dosage if any and dosage including globe perforation, lost muscle, splitting of muscle, sili-
of MR recession when performed. cone band related complications and anterior segment ischae-
mia. A success was defined as postoperative deviation ≤20PD at
OPERATIVE TECHNIQUE the last follow-up.
Under general anaesthesia, an intraoperative FDT was per-
formed to assess the tightness of each of the rectus muscles. A STATISTICAL ANALYSIS
fornix based conjunctival incision was placed in the supero- In patients, a paired t test was used to evaluate changes in
temporal quadrant approximately 10–12 mm from the limbus. maximum angles of abduction and elevation, and ocular devi-
The LR was hooked and isolated using muscle hooks and tenon ation. Statistical analyses were performed using commercial soft-
capsule reflected. The SR was hooked and isolated in a similar ware (Stata V.11; StataCorp, College Station, Texas, USA).
manner from the same incision. The paths of both LR and SR A p value<0.05 was considered statistically significant.
were examined intraoperatively and documented. Care was
taken to avoid superior oblique inclusion while operating on the RESULTS
SR. A scleral tunnel of 3–4 mm length was then constructed 14– A total of 26 eyes of 15 patients (male (9):female (6)=1.5:1)
16 mm from the limbus in between the bellies of SR and LR underwent silicone band loop myopexy during the study period.
using a hockey J stick buckle blade (Sharpedge, Gujarat, India) The mean age at surgery was 27.87±16.4 years (range
(figure 5A). A type 240 silicone band (Figure 5B) (Mira, 7–72 years). The mean age at onset of strabismus was
Uxbridge, Massachusetts, USA) was then passed under the LR 17.8±17.48 years. Mean follow-up duration was 7.93±8.48
and through the scleral tunnel and under SR (figure 5C). The months (range 2–28 months, and median 4 months). Eleven
two ends were then passed through a Watzke sleeve (Mira) patients underwent bilateral loop myopexy whereas four patients
Table 1 Distribution of the demographic and clinical features of all the patients in the series
BCVA Axial Length
(logMar) (mm) Preoperative deviation Deviation at last follow-up
Patient OD OS OD OS Esotropia (PD) Hypotropia (PD) Surgery performed Esotropia (PD) Hypotropia (PD)
Clinical science
Figure 1 Modified silicone band loop myopexy: Box and whisker plot Figure 3 Modified silicone band loop myopexy: Box and whisker plot
showing the distribution of abduction limitation in patients at showing the distribution of mean esotropia at presentation and last
presentation and last follow-up. follow-up.
underwent unilateral loop myopexy (table 1). Additional MR Mean esotropia at presentation was 79.3±32.3PD (range 30–
recession was performed in 10 patients (16 eyes) (four unilateral 130), which improved to 16.9±17.4PD (range 0–50),
and six bilateral) (table 1). The range of MR recession performed p=0.0000 (figure 3) and success (deviation within 20PD) was
was 5–7.5 mm. In one patient, a bilateral loop myopexy was per- achieved in 73% (95% CI 48 to 89%) at the last follow-up.
formed 1 month following the bilateral MR recession recession. Mean hypotropia at presentation was 8.9±10.1PD (range 0–
One eye had undergone an LR resection of 5.5 mm and MR 25PD), which improved to 0.64±1.33PD (range 0–4PD),
recession of 7 mm in addition to a unilateral loop myopexy. p=0.0069. Two patients had foreign body sensation due to sili-
Four patients had horizontal binocular diplopia at presenta- cone band which necessitated removal of two eyes. There was
tion. At the last follow-up, only one patient had minimal persist- no incidence of anterior segment ischaemia or other adverse
ing diplopia. In all, 24 eyes had nasalisation of SR and inferior events due to silicone band in any of the patients.
displacement of LR on MRI orbit. The remaining two eyes were
not found to have the an anomalous path of LR and SR on the DISCUSSION
MRI but found to have an anomalous downshift of the insertion The management of MSF has undergone a paradigm shift in the
of MR and LR intraoperatively in addition to the altered paths past decade.1 6 9 12 This advancement has been possible largely
of LR and SR, which were not seen on MRI orbit. The mean SE due to better understanding of the pathogenesis of this condi-
refraction was −16.3±6.3 dioptres (range −6 to −27, n=14) tion.1 2 7 Herzau and Loannakis13 for the first time observed
and mean best corrected visual acuity was 1.6±0.93 (range 0.3 intraoperatively an abnormal path of the LR in MSF. However,
to 3) logMar at presentation. Mean AL was 31.98±3.02 mm it was Krzizok and Schroeder7 who for the first time identified a
(range 26.8–36.46, n=24). shift in LR which was also seen on MRI as a pathogenesis of
Mean abduction limitation at presentation was −2.9±1.2 (−6 this condition. This study put to rest various older theories like
to −1) which improved to −1.5±1.3 (−5 to 0), p=0.0000 at myositis theory by Hugonnier and Magnard,14 LR paralysis
the last follow-up (figure 1). Mean elevation limitation at pres- theory of Paufique and others, theory of myopathic paralysis of
entation was −2.8±1.1 (−6 to −1) which improved to −1.2 the LR by pressure from the lateral orbital wall by Bagolini
±0.9 (−3 to 0), p=0.0000 at the last follow-up (figure 2). et al3 and so on. Herzau and Loannakis13 and Krzizok and
Schroeder7 recommended upshifting of the LR in order to
correct its path and thereby normalising the vector forces as the
treatment of MSF based on their findings. However, both the
author groups could not explain the limitation of elevation seen
in patients with MSF. Yokoyama et al2 reported abnormalities in
the path of both LR and SR secondary to supertemporal disloca-
tion of the posterior portion of the elongated globe out from
the muscle cone as seen in MSF and thereby successfully
explained the cause for eye being fixed in esotropic and hypo-
tropic position in MSF. The shifts in position of LR and SR
have been further studied by various authors using MRI and
have reiterated the findings of Yokoyama et al.1 2 7 8 Based on
their observation, Yokoyama et al2 15 recommended muscle
belly union of SR and LR by means of loop myopexy as the
treatment for MSF. Currently, suture loop myopexy with or
without scleral fixation and with or without MR recession is the
procedure of choice for MSF and its effectiveness is well
Figure 2 Modified silicone band loop myopexy: Box and whisker plot established.6 11 12 15
showing the distribution of limitation of elevation in patients at The potential disadvantages of suture loop myopexy are
presentation and last follow-up. muscle cheese wiring, strangulation of anterior ciliary circulation
38 Shenoy BH, et al. Br J Ophthalmol 2015;99:36–40. doi:10.1136/bjophthalmol-2014-305166
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Clinical science
Figure 4 Patient 12 with myopic strabismus fixus. (Left) Preoperative 9-gaze photograph showing 70 prism dioptres esotropia with restriction of
abduction and elevation. (Right) 9-Gaze photograph of the patient at last follow-up showing improved extra-ocular movements with orthotropia.
and the procedure being potentially non-reversible.12 16 ≤20PD. This was achieved in 73% patients (95% CI 48 to 89%).
Different materials have been used to perform a loop myopexy In all, 53.3% of the patients had a final deviation of ≤10PD.
in order to overcome the disadvantages of the suture loop Figure 4 shows a collage of preoperative and postoperative
myopexy.12 16 We have been using a modified loop myopexy photographs of patient 12 who had 70PD esotropia preopera-
with the help of a type 240 silicone band with scleral fixation tively and underwent bilateral silicone band loop myopexy. The
by constructing a scleral tunnel in treatment of MSF. Wong patient was orthotropic at the last follow-up.
et al12 reported favourable outcomes in an isolated case treated Five patients underwent silicone band loop myopexy without
with silicone band loop myopexy without scleral fixation MR recession. Even in patients who underwent bilateral loop
14 months postoperatively. The authors believe that silicone myopexy, a unilateral MR recession was performed in three
band loop myopexy without scleral fixation has an increased eyes. The decision to perform an additional MR recession was
risk of migration of the band especially in eyes with large AL. taken based on the intraoperative FDT before and after per-
Hence we modified the procedure with scleral fixation. forming a silicone band loop myopexy and based on the sur-
The mean AL in the present cohort was 31.98±3.02 mm, geon’s (RK) assessment of the tightness of MR. The total
which was comparable with previous studies on MSF.6 9 11 12 16 cumulative esotropia in five patients (seven eyes) who under-
The mean age of the patient in the present study was 27.87 went isolated loop myopexy without MR recession was 330PD.
±16.4 years which was lower than that reported in previous At the last follow-up, the cumulative esotropia in these patients
studies.6 11 12 The present study found that silicone band loop postoperatively was 40PD. Hence, it can be inferred that sili-
myopexy significantly improved ocular alignment and cone band loop myopexy alone effectively corrects approxi-
extra-ocular motility (figures 1–3). This was consistent with the mately 40PD of esotropia (330/7=47).
previous reports on effectiveness of suture loop myopexy6 9 11 12 The potential complications with our technique are intrao-
thereby implying that silicone band loop myopexy was as effect- perative scleral perforation and postoperative foreign body sen-
ive as suture loop myopexy. We defined success as a deviation sation due to the presence of the band-sleeve complex. We did
Figure 5 (A–F) Intraoperative photographs showing modified silicone band loop myopexy. (A) Making a scleral tunnel using a hockey J stick knife
about 12 mm posterior to the limbus in the superotemporal quadrant between superior rectus and lateral rectus muscles. (B) Passing the type 240
scleral band below the superior rectus and the scleral tunnel. (C) Passing the type 240 scleral band around the lateral rectus muscle. (D) Passing the
two ends of type 240 scleral band through the Watzke sleeve. (E) Tightening the scleral band through the scleral buckle. (F) Final appearance after
tightening the scleral band showing the close apposition of the superior and lateral rectus muscles using the band.
Shenoy BH, et al. Br J Ophthalmol 2015;99:36–40. doi:10.1136/bjophthalmol-2014-305166 39
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Clinical science
not have a scleral perforation in any of the eyes. Foreign body Patient consent Obtained.
sensation was reported by two patients (three eyes) and a sili- Data Sharing Data available on request. Requests to be directed to the
cone band removal was performed in two eyes of one patient corresponding author.
5 months postoperatively. The patient is maintaining alignment
24 months postoperatively. The other patient was lost to
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Notes