9 January 2019

Drugs used in Diabetes (A10)

 Insulins and Analogues (A10A)

1. Insulin (human):
a. Biphasic insulin
b. Biphasic Isophane
Human Insulin
c. Human Regular Solution for Injection
Insulin (I.M./S.C./I.V.); Solution
d. Insulin human + 100 I.U./mL for Injection (S.C./I.V.);
Isophane Insulin Solution for Injection
Human (S.C.); Suspension for
e. Neutral Insulin Human Injection (S.C.)
+ Isophane Insulin
Human
f. Recombinant Human
Insulin
2. Insulin aspart
a. Insulin aspart
b. Biphasic Insulin
Aspart
c. Biphasic Insulin 100 Units/mL Solution for Injection (S.C.)
Aspart 30
d. Biphasic Insulin
Aspart 50
3. Insulin degludec 100 Units/mL Solution for Injection (S.C.)
4. Insulin degludec and Insulin 100 Units/mL (70% Insulin
aspart Degludec/30% Insulin Solution for Injection (S.C.)
Aspart)
5. Insulin degludec and
100 Units/3.6 mg per mL Solution for Injection (S.C.)
Liraglutide
6. Insulin detemir 100 Units/mL Solution for Injection (S.C.)
7. Insulin glargine 100 Units/mL
Solution for Injection (S.C.)
300 Units/mL
8. Insulin glargine and 3.64 mg (equivalent to 100
Lixisenatide Units of Insulin glargine/
33 mcg per mL Solution)
Solution for Injection (S.C.)
3.64 mg (equivalent to 100
Units of Insulin glargine/
50 mcg per mL Solution)
9. Insulin glulisine 3.49 mg / mL (equivalent Solution for Injection (S.C.)
to 100 units / mL) Solution for Injection
 (Subcutaneous/Continuous
S.C. Pump
Infusion/Intravenous)
10. Insulin lispro
Solution for Injection
a. rDNA origin
(I.V./S.C./I.M.)
b. 50% Insulin Lispro
and 50% Insulin-
Lispro-Protamine
100 Units/mL (3.5 mg/mL)
Sulfate Suspension for Injection
c. 25% Insulin Lispro (S.C.)
and 75% Insulin-
Lispro-Protamine
Sulfate

 Blood Glucose Lowering Drugs, excluding Insulins (A10B)

A. Biguanides (A10BA)
1. Metformin Tablet
Film-Coated Tablet
500 mg Extended-Release Tablet
Sustained-Release Capsule
Oral Solution
750 mg Extended-Release Tablet
Tablet
Film-Coated Tablet
850 mg
Extended-Release Tablet
Oral Solution
Tablet
Film-Coated Tablet
1000 mg Extended-Release Tablet
Sustained-Release Capsule
Oral Solution
B. Sulfonylureas (A10BB)
1. Glibenclamide 5 mg Tablet
2. Glipizide Tablet
2.5 mg
Extended-Release Tablet
Tablet
5 mg Extended-Release Tablet
Controlled-Release Tablet
Extended-Release Tablet
10 mg
Controlled-Release Tablet
3. Gliclazide Modified-Release Tablet
30 mg
Prolonged-Release Tablet
60 mg Modified-Release Tablet
 Tablet
80 mg
Modified-Release Tablet
4. Glimepiride 1 mg
2 mg
Tablet; Film-Coated Tablet
3 mg
4 mg
C. Combinations of oral blood glucose lowering drugs (A10BD)
1. Metformin and
Sulfonylureas
a. Metformin and
500 mg + 5 mg Tablet
Glipizide
b. Metformin and 500 mg + 80 mg Film-Coated Tablet
Gliclazide 850 mg + 80 mg
c. Metformin and 500 mg + 1 mg Tablet
Glimepiride Tablet
Film-Coated Tablet
500 mg + 2 mg Sustained-Release Capsule
Extended-Release Tablet
Prolonged-Release Tablet
1 g + 2 mg Tablet
d. Metformin and 250 mg + 1.25 mg
Glibenclamide 500 mg + 2.5 mg Film-Coated Tablet
500 mg + 5 mg
500 mg + 5mg
Tablet
1 g + 5 mg
2. Metformin and Pioglitazone 500 mg + 15 mg
Film-Coated Tablet
850 mg +15 mg
3. Glimepiride and Pioglitazone 15 mg/2 mg
Tablet
30 mg/2 mg
4. Metformin and Sitagliptin Tablet
50 mg + 500 mg
Film-Coated Tablet
50 mg + 850 mg Tablet
50 mg + 1000 mg Tablet
50 mg + 1 g Film-Coated Tablet
100 mg + 1 g Extended-Release Tablet
5. Metformin and Vildagliptin 50 mg + 500 mg
50 mg + 850 mg Film-Coated Tablet
50 mg + 1000 mg
6. Pioglitazone and Alogliptin 12.5 mg/15 mg
12.5 mg/30 mg
Film-Coated Tablet
25 mg/15 mg
25 mg/30 mg
7. Metformin and Saxagliptin 2.5 mg/1 g
Film-Coated Tablet
5 mg/500 mg
 5 mg/1 g
8. Metformin and Linagliptin 2.5 mg + 500 mg
2.5 mg + 850 mg Film-Coated Tablet
2.5 mg + 1000 mg
9. Metformin and Dapagliflozin 5 mg/500 mg
5 mg/1000 mg
Tablet
10 mg/500 mg
10 mg/1000 mg
10. Linagliptin and 10 mg/5 mg
Film-Coated Tablet
Empagliflozin 25 mg/5 mg
11. Metformin and 5 mg/500 mg
Empagliflozin 5 mg/850 mg
5 mg/1 g
Film-Coated Tablet
12.5 mg/500 mg
12.5 mg/850 mg
12.5 mg/1 g
12. Pioglitazone, Metformin and 15 mg/500 mg/1 mg
Film-Coated Tablet
Glimepiride** 15 mg/500 mg/2 mg
13. Saxagliptin and
5 mg/10 mg Film-Coated Tablet
Dapagliflozin
D. Alpha glucosidase inhibitors (A10BF)
Tablet
50 mg
1. Acarbose Film-Coated Tablet
100 mg Tablet
Tablet
200 mcg
Orally Disintegrating Tablet
2. Voglibose
Tablet
300 mcg
Dispersible Tablet
E. Thiazolidinediones (A10BG)
Tablet
15 mg
Film-Coated Tablet
1. Pioglitazone
30 mg Tablet
45 mg Tablet
F. Dipeptidyl peptidase 4 (DPP-4) inhibitors (A10BH)
1. Sitagliptin 25 mg
50 mg Film-Coated Tablet
100 mg
2. Vildagliptin 50 mg Tablet
2.5 mg
3. Saxagliptin Film-Coated Tablet
5 mg
4. Linagliptin 5 mg Tablet
5. Gemigliptin 50 mg Film-Coated Tablet
6. Sitagliptin and Simvastatin 100 mg + 10 mg
Film-Coated Tablet
100 mg + 20 mg
 100 mg + 40 mg
G. Glucagon-like peptide-1 (GLP-1) analogues (A10BJ)
Powder for Suspension for
2 mg
Injection (S.C.)
250 mcg/mL (5 mcg/dose)
1. Exenatide
Solution for Injection (S.C.)
250 mcg/mL (10
mcg/dose)
2. Liraglutide 6 mg/mL Solution for Injection (S.C.)
10 mcg + 0.2 mL
(0.15 mg/3 mL)
3. Lixisenatide Solution for Injection (S.C.)
20 mcg + 0.2 mL

H. Sodium-glucose co-transporter 2 (SGLT2) inhibitors (A10BK)

5 mg
1. Dapagliflozin Tablet
10 mg
100 mg
2. Canagliflozin Film-Coated Tablet
300 mg
10 mg
3. Empagliflozin Film-Coated Tablet
25 mg
I. Other blood glucose lowering drugs, excluding insulins
500 mcg
1. Repaglinide 1 mg Tablet
2 mg
2. Nateglinide 120 mg Film-Coated Tablet