Which of the following provides the best definition of pharmaceutics?

a) It is the study of dosage form design, including associated

manufacturing techniques
b) It is the study of the effect that drugs have on the body
c) It is the study of the effect that the body has on drugs
d) It is the study of how drugs can be chemically synthesised
Question 2

Most medicines are made up of the active pharmaceutical ingredient (API)

and various excipients. Which one of the following is NOT a possible
justification for formulating medicines in this way?

a) The excipients stabilise the API so that it does not degrade

appreciably before administration
b) The excipients reduce the possibility of the API irritating the
body
c) The API and the excipients each exert a pharmacological effect
d) The API is too potent to use undiluted
Question 3

Which one of the following is not a route of administration?

a) Intravenous (IV)
b) Oral
c) Topical
d) Dissolution
Question 4

A rectal suppository is used to treat a fever. This would represent what

type of drug delivery?

a) Parenteral and local

b) Parenteral and systemic
c) Enteral and local
d) Enteral and systemic
Question 5

Which one of the following medicines does not rely on topical drug
delivery?

a) Nasal spray
b) Anti-dandruff shampoo
c) Insulin pen
d) Nicotine patch
Question 6

Which one of the following is not a common dosage form for fentanyl?

a) Vaporizer
b) Lollipop
c) Transdermal patch
d) IV infusion
Question 7

Which one of the following is an example of the chemical modification of

an active pharmaceutical ingredient?

a) Converting a crystalline API into an amorphous form

b) Combining a basic API with citric acid to produce the citrate
salt of the API
c) Mixing a poorly soluble API with water to produce a suspension
d) Mixing a soluble API with water to produce a solution
Question 8

Express 50 mg in kg.

a) 5 x 10 -3
kg
b) 5 x 10 -4
kg
c) 5 x 10 -5
kg
d) 5 x 10 -6
kg
Question 9
A pressure of 1 atm is equivalent to 101325 Pa. Alternatively, this can be
expressed as which one of the following?

a) 1.01325 MPa
b) 0.101325 MPa
c) 1013.25 kPa
d) 10.1325 kPa
Question 10

A volume of 10 dm may also be expressed as which one of the following?

3

a) 1 x 10 L -3

b) 10 L
c) 0.1 m 3

d) 0.001 m 3

Question 1

Of the following oral liquid formulations which would be considered as an

oropharyngeal formulation?

a) Syrup
b) Elixir
c) Mouthwash
d) Linctus
Question 2

Which of the following formulations would not be applicable to ocular

administration?

a) Solution
b) Liniment
c) Suspension
d) Ointment
Question 3

A tablet to treat a headache must first be dissolved in water before

swallowing. Which one of the following best describes this type of tablet?
 a) Modified release
b) Oral disintegrating
c) Effervescent
d) Buccal
Question 4

Capsules normally fall into two main categories. Which are they?

a) Hard gelatin capsules and soft gelatin capsules

b) Hard gelatin capsules and layered capsules
c) Soft gelatin capsules and compressed capsules
d) Compressed and layered capsules
Question 5

Intravenous, intramuscular and subcutaneous are all examples of which

routes of administration?

a) Pulmonary administration
b) Parenteral administration
c) Otic administration
d) Ocular administration

Question 6

Where is the site of administration for a dosage form that uses

transdermal delivery?

a) The eyes
b) The lungs
c) Under the tongue
d) The skin
Question 7
Which of the following dosage forms delivers the API to the GI tract?

a) Rectal suppositories
b) Nasal sprays
c) Vaginal pessaries
d) Eye drops
Question 8

Name two different types of inhaler?

a) MDI & API

b) IV & SC
c) DPI & MDI
d) GIT & ATP
Question 9

Nasal administration is commonly used for the relief of?

a) Headache
b) Cough
c) Sore throat
d) Congestion
Question 10

Ocular administration involves the treatment of which area?

a) The skin
b) The eyes
c) The ears
d) The lungs

Question 1
When some solutes are added to some solvents, the viscosity of the
resultant solution is found to be greater than that of the original solvent.
However, 'raising of viscosity' is not a colligative property. Why is this?

a) The viscosity of the resultant solution depends on the amount

of solute added.
b) The viscosity of the resultant solution depends on the amount
of pure liquid.
c) The viscosity of the resultant solution depends on the nature of
the solute added.
d) The viscosity of the resultant solution depends on the nature of
the pure liquid.
Question 2

At 75 C, the vapour pressure of pure water is 39 kPa. Which one of the

o

following is the most likely vapour pressure for a 1.5 M solution of sucrose
(aq) at the same temperature?
a) 37 kPa
b) 39 kPa
c) 0 kPa
d) 41 kPa
Question 3

Which of the four colligative properties arises in systems where there is

an equilibrium between a liquid solution phase and a second liquid phase?

a) Lowering of vapour pressure

b) Lowering of melting point
c) Raising of boiling point
d) Osmotic pressure
Question 4

Which of the following is the best description of a semipermeable

membrane in the context of osmosis?

a) A membrane that allows neither solute nor solvent particles to

pass through it.
 b) A membrane that allows solute particles, but not solvent
particles, to pass through it.
c) A membrane that allows solvent particles, but not solute
particles, to pass through it.
d) A membrane that allows both solute and solvent particles to
pass through it.

Question 5

State the van't Hoff factor (i) for a dilute aqueous solution of the strong
electrolyte barium hydroxide, Ba(OH) 2

a) 0
b) 1
c) 2
d) 3
Question 6

The van't Hoff equation may be written as P = 1000 i [S] RT, where all
terms have their usual meanings. Calculate the osmotic pressure of a 0.2
M solution of NaCl at 25 C given R =8.314 J K mol .
o -1 -1

a) 990 kPa
b) 500 kPa
c) 83 kPa
d) 42 kPa
Question 7

A cell is bathed is a solution that has a greater osmolarity than that of the
cytosol. This solution is best described as which one of the following?

a) Isotonic
b) Hypertonic
c) Hypotonic
d) None of the above
Question 8

What is the typical osmolarity of physiological fluids?

 a) 300 Mosmol L -1

b) 0.3 mosmol L -1

c) 300 osmol L -1

d) 0.3 osmol L -1

Question 9

Which one of the following is not an essential component of an osmotic

pump drug delivery tablet?

a) Contain an active pharmaceutical ingredient (API)

b) Contain a single chamber
c) Coated with a semipermeable membrane
d) Have a orifice in the tablet coating
Question 10

For ideal systems, the reduction in the chemical potential of solvent

molecules upon the addition of solute depends only on which one of the
following?
a) The melting point of the solute.
b) The solubility of the solute.
c) The number of solute particles.
d) The boiling point of the solute.