Case No.

1
Test Patient’s value Normal values Units
Hgb 6.6 11.5 – 15.5 g/dl
Hct 23% 41 – 47%
RBCs/eritrocite 3.4 x 10⁶/mm³ 4.1 – 4.6 x 10⁶/mm³
MCV/VEM 68 80 - 100 fl
MCHC/CHEM 28.7 32 - 34 g/dl erythrocytes
RDW 21.5% 11 – 15%
Reticulocyte count/reticulocite 7‰ 5 - 15‰
WBC/Leucocite 8,100/mm³ 4,000 – 10,000/mm³
Platelets/trombocite 480.000/mm³ 150,000 – 400,000/mm³
Total serum proteins/proteine 7.1 6.5 - 8 g/dl
serice totale
Fibrinogen 440 200 - 400 mg/dl
Bleeding Time/Timp de sângerare 11.5 6 - 10 minutes
LTA ADP/test de agregare la ADP Normal
LTA Ristocetin/test de aglutinare la ↓
ristocetină
Ristocetin Cofactor 12% 65 – 120%
Assay/Activitatea cofactorului
ristocetinic
APTT 55 27 - 35 seconds
Prothrombin Time/TQ 14.5 13 – 15.5 seconds
dRVVT 34 25 - 35 seconds
Thrombin Time/TT 14 10 - 15 seconds
ALT 33 10 - 40 U/l
AST 25 10 - 35 U/l
LDH 212 115 - 220 U/l
Total bilirubin 1.1 0.3 – 1.2 mg/dl
Unconjugated (indirect) bilirubin 0.9 0.2 – 1 mg/dl
Direct bilirubin 0.2 0 – 0.2 mg/dl
Total serum iron/sideremie 20 50 – 150 μg/dl
TIBC/CTLF 400 300 - 400 μg/dl
Transferrin saturation/saturația 5% 20 – 50%
transferinei
Serum ferritin/feritina serică 12 30 - 300 ng/ml
Serum folate/folați serici 6.9 >5,5 ng/dl
Serum vitamin B12/vit. B12 serică 560 220 - 850 pg/dl

Case No. 2
Test Patient’s value Normal values Units
Hgb 5.4 11.5 – 15.5 g/dl
Hct 18 41 – 47%
RBCs/eritrocite 2.9 x 10⁶/ mm³ 4.1 – 4.6 x 10⁶/ mm³
MCV/VEM 62 80 - 100 fl
MCHC/CHEM 30 32 - 34 g/dl erythrocytes
Reticulocyte count/reticulocite 1‰ 5 - 15‰
WBC/Leucocite 8.900 4,000 – 10,000/ mm³
Platelets/trombocite 500.000 150,000 – 400,000/ mm³
Total serum iron/sideremie 172 50 – 150 μg/dl
TIBC/CTLF 258 300 - 400 μg/dl
Transferrin saturation/saturația 66.6% 20 – 50%
transferinei
Serum ferritin/feritina serică 391 30 - 300 ng/ml
Hb electrophoresis = normal
Bone marrow (MOH): 60% ringed sideroblasts (sideroblaști inelari)
Case No. 3
Test Patient’s value Normal values Units
Hgb 6.7 11.5 – 15.5 g/dl
Hct 20.9% 41 – 47%
RBCs/eritrocite 1.77 x 10⁶/ mm³ 4.1 – 4.6 x 10⁶/ mm³
MCV/VEM 118 80 - 100 fl
MCHC/CHEM 32 32 - 34 g/dl erythrocytes
Reticulocyte count/reticulocite 25‰ 5 - 15‰
WBC/Leucocite 2,800/ mm³ 4,000 – 10,000/ mm³
Platelets/trombocite 96,000/ mm³ 150,000 – 400,000/ mm³
Total serum proteins/proteine 6.5 6.5 - 8 g/dl
serice totale
Fibrinogen 378 200 - 400 mg/dl
APTT 35 27 - 35 seconds
Prothrombin Time/TQ 15.5 13 – 15.5 seconds
ALT 29 10 - 40 U/l
AST 25 10 - 35 U/l
GGT 41 10 - 55 U/l
LDH 1,354 115 - 220 U/l
ALP 62 35 - 96 U/l
Amylase 20 20 - 96 U/l
CK-MB 2.1 0 – 5.5 μg/l
Total bilirubin 2.6 0.3 – 1.2 mg/dl
Unconjugated (indirect) bilirubin 2.2 0.2 – 1 mg/dl
Direct bilirubin 0.4 0 – 0.2 mg/dl
Total cholesterol 220 120 - 200 mg/dl
Triglycerides 290 45 - 150 mg/dl
Glucose 145 70 - 120 mg/dl
Total serum iron/sideremie 145 50 – 150 μg/dl
Serum folate/folați serici 6.1 >5,5 ng/dl
Serum vitamin B12/vit. B12 serică 115 220 – 850 pg/dl

Schilling test Testul Schilling

 1st phase = 1.2 % (N>7%)  Prima etapă = 1.2 % (N>7%)
 2nd phase = 12.4 % (N>7%)  A II- a etapă = 12.4 % (N>7%)
Antibodies anti FI (+) Anticorpi anti FI (+)

Case No. 4
Test Patient’s value Normal values Units
Hgb 7.9 11.5 – 15.5 g/dl
Hct 24.5% 41 – 47%
RBCs/eritrocite 2.3 x 10⁶/ mm³ 4.1 – 4.6 x 10⁶/ mm³
MCV/VEM 106.5 80 - 100 fl
MCHC/CHEM 32.2 32 - 34 g/dl erythrocytes
Reticulocyte count/reticulocite 34% 0.5 – 1.5%
RDW 19% 11 – 15%
WBC/Leucocite 11,410 4,000 – 10,000/ mm³
Platelets/trombocite 358,000 150,000 – 400,000/ mm³
Total serum proteins/proteine 6.7 6.5 - 8 g/dl
serice totale
Fibrinogen 470 200 - 400 mg/dl
APTT 32 27 - 35 seconds
Prothrombin Time/TQ 14 13 – 15.5 seconds
ALT 38 10 - 40 U/l
AST 21 10 - 35 U/l
LDH 557 115 - 220 U/l
Total bilirubin 2.4 0.3 – 1.2 mg/dl
Unconjugated (indirect) bilirubin 2.2 0.2 – 1 mg/dl
Direct bilirubin 0.2 0 – 0.2 mg/dl
Haptoglobin <20 40 - 200 mg/dl
Glucose 142 70 - 120 mg/dl

Coombs’ direct test (+) for antibodies Test Coombs direct (+) pt. anticorpi

Case No. 5 (42ys, 42 ani)

Test Patient’s value Normal values Units
Hgb 6.81 11.5 – 15.5 g/dl
Hct 23.5% 41 – 47%
RBCs/eritrocite 3.59 x 10⁶/ mm³ 4.1 – 4.6 x 10⁶/ mm³
MCV/VEM 65.3 80 - 100 fl
MCHC/CHEM 29 32 - 34 g/dl erythrocytes
Reticulocyte count/reticulocite 27‰ 5 - 15‰
RDW 17% 11 – 15%
WBC/Leucocite 3,700/ mm³ 4,000 – 10,000/ mm³
Platelets/trombocite 289,000/ mm³ 150,000 – 400,000/ mm³
Fibrinogen 278 200 - 400 mg/dl
APTT 37 27 - 35 seconds
Prothrombin Time/TQ 16.5 13 – 15.5 seconds
ALT 98 10 - 40 U/l
AST 81 10 - 35 U/l
GGT 101 10 - 55 U/l
LDH 450 115 - 220 U/l
ALP 112 35 - 96 U/l
Amylase 78 20 - 96 U/l
CK-MB 4.1 0 – 5.5 μg/l
Total bilirubin 4.5 0.3 – 1.2 mg/dl
Unconjugated (indirect) bilirubin 3.7 0.2 – 1 mg/dl
Direct bilirubin 0.8 0 – 0.2 mg/dl
Total cholesterol 225 120 - 200 mg/dl
Triglycerides 197 45 - 150 mg/dl
Glucose 134 70 - 120 mg/dl
Total serum iron/sideremie 185 50 – 150 μg/dl
TIBC/CTLF 280 300 - 400 μg/dl
Transferrin saturation/saturația 66% 20 – 50%
transferinei
Serum ferritin/feritina serică 345 30 - 300 ng/ml
Serum folate/folați serici 5.6 >5,5 ng/dl
Serum vitamin B12/vit. B12 serică 310 220 - 850 pg/dl
Haptoglobin 35 40 - 200 mg/dl
Total serum proteins/proteine 6.1 6.5 - 8 g/dl
serice totale
Serum proteins electrophoresis/electroforeza proteinelor serice
Albumin 47% 60%
α1 - globulins 4% 4 – 6%
α2 - globulins 6% 6 – 9%
β - globulins 12% 9 – 12%
γ - globulins 31% (polyclonal) 12 – 20%
Hemoglobin electrophoresis: HbA1 =81.5%, HbA2 = 6.5% , HbF = 12%
Case No. 6
Test Patient’s value Normal values Units
Hgb 13.2 11.5 – 15.5 g/dl
Hct 41% 41 – 47%
RBCs/eritrocite 4.55 4.1 – 4.6 x 10⁶/ mm³
MCV/VEM 90 80 - 100 fl
MCHC/CHEM 32 32 - 34 g/dl erythrocytes
Reticulocyte count/reticulocite 11‰ 5 - 15‰
RDW 13.5% 11 – 15%
WBC/Leucocite 7,800 4,000 – 10,000/ mm³
Platelets/trombocite 346,800 150,000 – 400,000/ mm³
Fibrinogen 332 200 - 400 mg/dl
Bleeding Time/Timp de sângerare 8.7 6 – 10 minutes
LTA ADP/test de agregare la ADP normal
LTA Ristocetin/test de aglutinare normal
la ristocetină
APTT 76 27 - 35 seconds
Prothrombin Time/TQ 14 13 – 15.5 seconds
dRVVT 32 25 - 35 seconds

Correction tests for APTT Teste de corecție pt. APTT

APTT is corrected with old serum and normal fresh plasma APTT se corectează cu ser vechi și plamă proapătă normală
APTT is NOT corrected by fresh plama adsorbed on BaSO₄ (integrală)
APTT NU se corectează cu plasmă adsorbită pe BaSO₄

Case No.7
Test Patient’s value Normal values Units
Hgb 6.5 11.5 – 15.5 g/dl
Hct 19.1% 41 – 47%
RBCs/eritrocite 1.94 x 10⁶/ mm³ 4.1 – 4.6 x 10⁶/ mm³
MCV/VEM 98.4 80 - 100 fl
MCHC/CHEM 34 32 - 34 g/dl erythrocytes
Reticulocyte count/reticulocite 2.2‰ 5 - 15‰
RDW 15% 11 – 15%
WBC/Leucocite 2,200 4,000 – 10,000/ mm³
Platelets/trombocite 10,500 150,000 – 400,000/ mm³
Fibrinogen 118 200 - 400 mg/dl
Bleeding Time/Timp de sângerare 14.5 6 - 10 minutes
APTT 43 27 - 35 seconds
Prothrombin Time/TQ 17.5 13 – 15.5 seconds
D-dimer 7.8 <0.5 μg/ml
LDH 670 115 - 220 U/l
ALP 376 35 - 96 U/l

Bone marrow MOH

Hypercellular bone marrow due to abnormal immature Măduvă hipercelulară – datorită unor celule anormale și
cells – acute mieloid leukemia imature – leucemie acută mielocitară

Case No.8
Test Patient’s value Normal values Units
Hgb 10.1 11.5 – 15.5 g/dl
Hct 30.6% 41 – 47%
RBCs/eritrocite 3.15 x 10⁶/ mm³ 4.1 – 4.6 x 10⁶/ mm³
MCV/VEM 97 80 - 100 fl
MCHC/CHEM 33 32 - 34 g/dl erythrocytes
Reticulocyte count/reticulocite 15‰ 5 - 15‰
RDW 16% 11 – 15%
WBC/Leucocite 11,300 4,000 – 10,000/ mm³
Platelets/trombocite 58,000 150,000 – 400,000/ mm³
Fibrinogen 157 200 - 400 mg/dl
APTT 89 27 - 35 seconds
Prothrombin Time/TQ 19.8 13 – 15 seconds
FDP/PDF 67 <5 pg/ml
D-dimer 4.7 <0.5 μg/ml
ALT 62 10 - 40 U/l
AST 72 10 - 35 U/l
GGT 34 10 - 55 U/l
LDH 1,890 115 - 220 U/l
ALP 158 35 - 96 U/l
Amylase 249 20 - 96 U/l
Total bilirubin 2.5 0.3 – 1.2 mg/dl
Unconjugated (indirect) bilirubin 2.1 0.2 – 1 mg/dl
Direct bilirubin 0.4 0 – 0.2 mg/dl
Glucose 55 70 - 120 mg/dl
Creatinine 3.6 0.6 – 1.2 mg/dl
Haptoglobin <5 40 - 200 mg/dl
K 4.8 3.5 - 5 mmol/l
Na 134 136 - 146 mmol/l

WBC differentiated count: Ne = 87% (52% immature Formula leucocitară: Ne = 87% (52% neutrofile tinere)
forms)