Why was Tirupati temple not invaded or destroyed

by any invader unlike the temples Kashi, Ram

Janmabhoomi or Mathura?

It is Other way:

It would be interesting, if I say, because other temples were invaded (Sri Rangam, Madurai
Meeanakshi in 1323) Tirumala Tirupati becomes famous.

Sri Rangam was very famous in those days. When Malik Kafur invaded Sri Rangam in 1323.
The temple was defended and according to the Tamil tradition some 13,000 Sri Vaishnavas
devotees of Srirangam, died in the fierce battle.

Everyone looked for Safety:

They found Sri Rangam or Kanchi or Madurai were no longer safe. The idol of
Sriranganathar was taken through villages of Tamil Nadu, Kerala and Karnataka. They
finally went to the hills of Tirumala Tirupati, where they remained until the temple was
rebuilt in 1371.

Power of Balaji:

This is the power of Thiruvengadam Hills that it fulfilled the wishes of Gods and
redeveloped their temples (of Sri Ranganathar, Meenakshi, Sudareswar) within 48 years.
That is the reason, his devotees believe their wishes will be manifested within 48 days.

Journey through Seven Hills:

Earlier Tirumala Tirupati was inaccessible in the past due to its location in the Eastern
Ghatts. Early kings of Chola, Pallava, Pandya were liberal in providing grants and free
comforts to pilgrims as they have to negotiate hardship in travelling.

Political Importance & Formation of Hindu Kingdom:

Because of Ranganathar idol kept in Tirumala Tirupati for 48 years (It is called Ranga
Mandapam -now, without Ranganathar, at South West Corner of the Temple), this tiny
temple of Tamil country, become political importance. Till then the pilgrims were from
Tamil country. Now Tamils could meet Telugu and Kannada speaking Pallavas, Chalukyas
and Hoysalas because of Ranganathar.

Hoysalas try to liberate Maduarai but their king Ballala was killed in a battle. Finally
Vijayanagara Emperors liberated, Kanchi, Sri Rangam and Madurai. They (Bukkaraya’s Son
Kumara Kampanna and Saluva Narasimharaya’s grand father) used to frequent Tirupati in
those 48 years of Sri Rangnathar’s stay in Tirupati. (It took 200 years to rebulid the present
day Sri Rangam by Vijayanagara Kings, Maduari and Thanjavur Naickers.)Later Krishna
Devaraya and his successors patronised this temple with lot of Jewels, Gifts and Grants and
endowment of villages.
This too will pass:

After the destruction of Hampi in 1565 in Talikota war, its importance deteriorated.
However Vijayanagar Kings of Arvaitu Dyanasty patronised the temple for another 95 years
till 1660. No one dared to venture.

Low Profile:

It is sad to write here that, this country was ruled by many, region by region, part by part in
those days and they had vested interests.

After the extinct of Vijayanagara Empires, the invaders of Shaivite faith (Hindus),
administrators of Muslim Sulatns and East India Company (Christans) even negotiated the
Ghatts in a hard way to take away the treasures. They demanded two lakh rupees every year
for not destructing it. Even the documents of village endownments donated by the noble
kings were destroyed and thrown in the river. East India Company also did not want to
loose the Golden Goose by extracting two lakh rupess revenue every year.

That was the first time, after 1660, temple started charging money (to stay live) from
devotees for doing archanas, gifting vastras, offering hairs etc.

To sum up:

Tirupati is a very very small temple, but over 2000 years old. It was inaccessible in the past
due to its location in the Eastern Ghatts. Temples, have their life cycle, become famous in
certain points in time.It has earlier become centre of attraction from 14th to 17th century
and again gone unnoticed. Since a century earlier, now it has again become popular.