Cell-Based Assays Global Market

–Forecast to 2025

Cell-Based Assays Global Market estimated to be worth $20.1 billion by 2025

IQ4I Research & Consultancy published a new report on “Cell-Based Assays Global
Market – Forecast To 2025” This report analyzes and studies the overall market, major
Drivers & Opportunities, Restraints & Threats in North America, Europe, Asia-Pacific and
Rest of the World.

IQ4I’s Report Contains 111 market data tables and 102 figures spread through 467
pages and an exhaustive TOC on “Cell-Based Assays Global Market”, [PRODUCTS
{Consumables (Assay kits, cells, microplates, reagents and others), Instruments
(microplate readers, liquid handling systems, automated cell counters, microfluidic chips
and cell microarrays, high throughput screening, high content screening, microscopes,
others), Software and Services); APPLICATIONS (Pharma and Biotech {(Drug Discovery,
Drug Development, Manufacturing)}, Basic Research, Diagnostic and medical Devices,
Agro and Environmental, Cosmetics Testing, Food & Beverages, Chemical & Materials and
Others); REGION (North America (U.S., & Rest of North America, Europe (Germany, U.K.,
France, Rest of Europe), Asia-Pacific (China, Japan, India & Rest of APAC) and Rest of the
World (Brazil, Rest of Latam, Middle East & Others)]

Over the past few years, there has been a trend of adopting cell-based assays when
compared to biochemical assays, ligand binding assays and animal experiments as they
mimic real-life models in drug discovery, development, manufacturing of small molecules
and biologics to reduce developmental time and operational cost. The necessity for the
robust cell-based assays is growing with the increase in the approvals of biologics,
biosimilars and the need to meet the regulatory requirements. Thus, the demand for robust
target specific bioassays is the need of the hour to accelerate, shorten development and
manufacturing timelines of drug products. With several blockbuster biologics going off-patent
such as Herceptin (Trastuzumab) and Avastin (Bevacizumab) 2019, and Aranesp
(Darbepoetin Alfa) and Enbrel (Etanercept) in 2024 and 2028 respectively, there is a huge
opportunity for the development of off-the-shelf and custom cell-based potency assays. The
cell-based assays also plays an important role in basic research, cosmetics testing, medical
device, chemical, materials, agriculture products, food & beverages, and environmental
testing through various assays such as reporter gene assays, second messenger assay, cell
growth assays, cell death and motility assays.

According to IQ4I analysis, the cell-based assays global market is estimated to grow at
CAGR of 8.0% to reach $20.1 billion by 2025. The factors driving the market are rising use
of the cell-based assay in drug discovery and development, increasing focus on biologics,
technological advancements favoring the adoption of cell-based assays, the growing

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Cell-Based Assays Global Market

–Forecast to 2025

availability of funds for research. Whereas, factors such as lack of skilled professionals,
ethical concerns over the use of raw materials from animal sources, high cost of instruments,
lack of standardization, consistency and reproducibility issues are restraining the market
growth.

The cell-based assays market is segmented based on products, applications, and

geography. The products market includes consumables, instruments, software and services,
among them, consumables segment commanded the largest share in 2018 and is projected
to grow at the high single digit CAGR from 2018 to 2025. According to IQ4I analysis, among
consumables about 21.1 million microplates were consumed during 2018, this number is
expected to reach XX million by 2025 growing at mid single digit CAGR from 2018 to 2025.
Reporter gene assays are employed to study gene regulations, transcriptional regulation of
cells, promoter activity, cell signaling, gene expression in diagnostics, cancer research and
environmental testing is driving the assay kits market in consumables segment. Similarly,
reagents market which includes, media sera, dyes, stains and specialty chemicals occupies
the largest share in consumables.

In the applications market, the Pharma and Biotech commanded the largest revenue 2018
and is expected to grow at a high single digit CAGR to reach $12.1 billion by 2025. Rise of
discovery, development and manufacturing activity in biologics and biosimilar is driving the
growth of the pharma and biotech segment. Drug discovery market is expected to grow at a
high single digit CAGR. Increasing collaboration of basic research institutes with companies
and CROs for the development of disease models such as cancer, cardiovascular diseases,
neurodegenerative diseases (Alzheimer’s, dementia, Parkinson’s, Huntington’s, Bipolar
disorder, multiple sclerosis etc.), drug development, manufacturing, diagnostic, medical
devices testing, cosmetic testing and eco-toxicity study where cell-based assays are utilized
is driving the growth of cell-based assay applications market.

Technological advancements in a cell-based assay such as platforms for High Throughput

Screening (HTS), High-content screening (HCS), novel microscopy-based technologies,
increased automation in liquid handling instruments, and advanced software for automation
and data acquisition and analysis have proven to be valuable in drug discovery efforts. In
addition, advancements such as predictive toxicology, virtual screening, 3D bio-printing,
gene editing tools, are favoring the adoption of cell-based assays. Improvements in cellular
models, such as cell lines, primary cells, stem cells are being used as models for basic
research and drug discovery. Advancement in label-free technology such as dynamic mass

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Cell-Based Assays Global Market

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redistribution (DMR)-based on optical biosensors, and cellular dielectric spectroscopy

(CDS)- based on impedance biosensors are supporting the implementation of cell-based
assay in basic research.

The growing concern on the use of animals for toxicology and efficacy studies and
advantage of the cell-based assay in reducing time, cost and increasing accuracy,
reproducibility are fueling the adoption of in-vitro (animal-free) testing for regulatory
toxicology and to address efficacy concerns in the cosmetics, chemical, pharmaceutical and
household product industries. Several companies offer in-vitro tissue models and different
tissue specific testing services. For instance, Mattek Corp. offers various tissue models
derived from human primary cells for researcher to evaluate raw materials and final product
formulations. They also offer GLP and non-GLP toxicity testing services such as skin
irritation, corrosion, eye irritation, and phototoxicity.

Companies in this market are employing organic strategies such as new product launches,
approvals, collaborations and partnerships. For instance, in November 2018, Eurofins
Scientific, a global leader in biopharmaceutical products testing services, signed an
outsourcing agreement with Astellas to outsource one of its internal testing laboratories,
expanding its geographic presence in Japan. An inorganic strategy such as acquisition
expands product offering or help in gaining access to new markets. On April 2019, Charles
River Laboratories acquisition of Citoxlab, a CRO specialized in regulated safety
assessment services, non-regulated discovery services, and medical device testing with
operations in Europe and North America.

The cell-based assay geographical market consists of North America, Europe, Asia-Pacific
and RoW, where, North America dominates the market with largest share in 2018 due to
high R&D funding and presence of major pharma and biotech companies. The Asia-Pacific
market is expected to show strong growth from 2018 to 2025 due to increase in outsourcing
of drug development research and the emergence of this region as the manufacturing of hub
for biologics drugs.

Some of the key players in Cell-based assays market are Danaher (U.S.), ThermoFisher
Scientific (U.S.), Merck KGaA (Germany.), Becton, Dickinson and Company (U.S.), Perkin
Elmer, Inc. (U.S.), Lonza (Switzerland), Corning, Inc. (U.S.), Tecan (Switzerland), Bio-Rad
Laboratories, Inc. (U.S.), Biotek (U.S.), Promega Corporation (U.S.) and GE Healthcare
(U.S.)

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Reasons for buying this report:

 Cell-Based Assays Global Market is expected to grow at a CAGR of 8.0% from 2018
to 2025 to reach $20.1 billion by 2025.
 Identification and analysis of the cell-based assays global market by identifying
various segments: products, applications, and geography.
 Revenue forecast of the cell-based assays market and strategic analysis of each
sub-segment with respect to segmental growth trends.
 Identification of major market trends, Porter’s model, and factors driving, restraining,
threatening and providing opportunities for the cell-based assays market growth.
 Test kits cost, instruments cost and cell line cost details, acquisitions, collaborations,
expansions, drug discovery, development, and manufacturing services capabilities
matrix.
 Cell-based assays global market share analysis of major players.
 Revenue forecast of the cell-based assays market with respect to North America
(U.S., Rest of North America), Europe (Germany, U.K., France, and Rest of Europe),
Asia-pacific (China, Japan, India and Rest of Asia-Pacific) and Rest of the World
(Brazil, Rest of Latin America, Middle East and Others).
 Analysis of the opportunities for stakeholders by identifying the high-growth
segments of the market.
 Profiles of major players in cell-based assays global market and analysis of their
financial revenue, business strategies, SWOTs and market shares.

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Cell-Based Assays Global Market

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FIGURE 1

CELL-BASED ASSAYS GLOBAL MARKET SEGMENTATION

Cell-Based Assays Global Market

Products
Applications
Pharma &
Biotech
Software &
Consumables Instruments
Basic
Services
Drug Discovery
Research
Microfluidic
Assay kits chip & Cell Microplate
Drug Diagnostics & readers
Development Medical Microarray
Devices High Content
Cells Liquid
Manufacturing Screening Handling
Agro & Envtl
Testing High
Microplates Throughput Flow
Screening Cytometer
Cosmetics
Reagents Microscopes Automated
Food & Cell Counting
Beverage
Others Other
Chemical & Instruments
Material

Others

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