December 4th, 2016.

Dear sir:

Please answer in English.

If it is still good time and you are interested in the position we want to fill in, please
answer the following:

In a pharmaceutical loop where water is treated, stored and distributed, elaborate about
the following subjects: what is it the meaning of the words and numbers? Or, what is the
spec used for such concept? Or, in other words, tell us in a few words what you know
about each item.
1. SS316L
2. ASME BPE SF1
3. A269, A270
4. Ra
5. TIG
6. ORBITAL WELDING
7. PASSIVATION and ELECTROPOLISHING.
8. 2WC y L2S ELBOWS
9. 88° ELBOWS
10. DIAPHRAGM VALVES.
11. NEUMATIC ACTUATORS
12. FRISTAM PUMPS vs. TRADITIONAL CENTRIFUGAL PUMPS
13. SPEC TO FOLLOW FOR FABRICATING TANKS.
14. AND FOR HEAT EXCHANGERS.
15. WHEN DESIGNING A HEAT EXCHANGER, WHAT IS THE MEANING OF
“FOULING FACTOR”?
16. COFEPRIS
17. NOM 059
18. INSULATION FOR CLEAN ROOMS

Please send your answers to the undersigned and copy to your agent.
1. SS 316L is an austenitic Chromium-Nickel stainless steel with superior corrosion
resistance. The low carbon content reduces susceptibility to carbide precipitation
during welding.
2. ASME BPE (Bioprocessing Equipment) is leading standard on how to desing and
build equipment and systems used in the production of biopharmaceuticals, which
includes bioprocessing, pharmaceutical and personal care products.
3. A269. This specification covers nominal-wall-thickness, seamless and welded
austenitic steel tubing for general corrosion-resisting and low- or high-temperature
service. All material shall be furnished in the heat-treated condition. The steel shall
conform to the chemical composition requirements. Different mechanical test
requirements that includes, flaring test, flange test, hardness test, and reverse
flattening test are presented. A270. This specification covers grades of seamless,
welded, and heavily cold worked austenitic and ferritic/austenitic stainless steel
sanitary tubing. Seamless tubes shall be manufactured by a process that does not
involve welding at any stage. Welded tubes shall be made using an automated
welding process with no addition of filler metal during the welding process. It refers
the surface finished like mill finish, mechanically polished and electropolished.
4. Ra is the average of a set of individual measurements of a surfaces peaks and
valleys.
5. The TIG (Tungsten Inert Gas) process is used Widely and is very suitable for
welding steel stainless. An inert gas (usually argon) is used To protect the molten
metal from welding from the air. Yes Is needed, addition metal is added in the form
of Wire inside the bow, either manually or automatically.
6. In the orbital welding process,tubes/pipes are clamped in place, and an orbital
weldhead rotates an electrode and electric arc around the weld joint to make the
required weld. An orbital welding system consists of a power supply and an orbital
weldhead.
7. Passivation is a non-electrolytic process which removes iron from the surface,
rendering stainless steel more rust proof. Electropolishing is an electrolytic process
which dissolves the asperities to leave an ultra smooth surface for such reasons as
cleanliness and to prevent materials from sticking. Both are traditionally done with
very strong and concentrated acids.
8. 2WC Short. Butt welding sanitary connection are applied in process piping systems.
L2S. It’s tangent and has one end or both ends of the elbow has extra length added.
9. Used in pharmacy, beer, food, dairy, beverage, cosmetic, chemical industry.
10. Diaphragm Valves are used in the pharmaceutical industry avoiding a point of
contamination on the line. These Valves are also called as “membrane type valves”
since the diaphragm or membrane is the central mechanism through which liquids
will pass.
11. A pneumatic actuator is a device that is capable of converting energy from a
pressurized gas into motion.
12. No external cooling devices are required for seals or other components. In fact, most
Fristam pumps can be used with condensed steam as a seal rinse fluid.
13. For storage tanks. API 620, API 650, API 653. For Vessel on pressure. ASME VIII
14. Code ASME Seccion VIII
15. The fouling factors to be used in the design of heat exchangers are normally
specified by the client based on his experience of running his plant or process to
simulate dirt accumulation on the heat transfer surfaces.
16. The Federal Commission for Protection against Sanitary Risks (Cofepris) is a
federal agency (a decentralized body) of the Mexican government, linked to the
Department of Regulation and Health Promotion of the Ministry of Health.
17. This Standard provides de minimum requirements for the manufacturing process of
medicines for human use and research purposes.
18. The insulation in the process lines is critical in clean environments. The insulation
can be support low and high temperature. The insulation usually made with foam
and it is compliant with FM Standard for cleanroom materials.